Emmott
New preprint on the nuts and bolts of SCOPE2
Aleksandra A Petelski, Edward Emmott, Andrew Leduc, R. Gray Huffman, Harrison Specht, David H Perlman, Nikolai Slavov (2021) Multiplexed single-cell proteomics using SCoPE2 doi: https://doi.org/10.1101/2021.03.12.435034
This article is a preprint and has not been certified by peer review [PDF] [DOI] [Abstract...]
This article is a preprint and has not been certified by peer review [PDF] [DOI] [Abstract...]
Single cell proteomics on macrophages
Harrison Specht, Edward Emmott, Aleksandra A. Petelski, R. Gray Huffman, David H. Perlman, Marco Serra, Peter Kharchenko, Antonius Koller and Nikolai Slavov (2021) Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 Genome Biol 22(1):50. doi: 10.1186/s13059-021-02267-5. [PDF] [PUBMED] [DOI] [Abstract...]
Regulation of norovirus infection by Ifit1
Harriet V Mears, Edward Emmott, Yasmin Chaudhry, Myra Hosmillo, Ian G Goodfellow, Trevor R Sweeney (2019) Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells. [PDF] [PUBMED] [DOI] [Abstract...]
Norovirus mode of action
Myra Hosmillo , Jia Lu, Michael R McAllaster, James B Eaglesham, Xinjie Wang, Edward Emmott, Patricia Domingues, Yasmin Chaudhry, Tim J Fitzmaurice, Matthew Kh Tung, Marc Dominik Panas, Gerald McInerney, Nicolas Locker, Craig B Wilen, Ian G Goodfellow (2020) Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation [PDF] [PUBMED] [DOI] [Abstract...]
Novel proteolytic events in SARS-Cov-2 infection
Bjoern Meyer, Jeanne Chiaravalli, Philip Brownridge, Dominic P. Byrne, Leonard A. Daly, Fabrice Agou, Claire E. Eyers, Patrick A. Eyers, Marco Vignuzzi, Edward Emmott (2020) Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing [DOI] [PDF] [Abstract...]
The COVID-19 MS coalition
Weston Struwe, Edward Emmott, Melanie Bailey, Michal Sharon, Andrea Sinz, Fernando J Corrales, Kostas Thalassinos, Julian Braybrook, Clare Mills, Perdita Barran, COVID-19 MS Coalition (2020) The COVID-19 MS Coalition-accelerating diagnostics, prognostics, and treatment. [PDF] [PUBMED] [DOI] [Abstract...]
Temporal proteomics of herpes virus infection
Timothy K Soh, Colin T R Davies, Julia Muenzner, Leah M Hunter, Henry G Barrow, Viv Connor, Clément R Bouton, Cameron Smith, Edward Emmott, Robin Antrobus, Stephen C Graham, Michael P Weekes, Colin M Crump(2020) Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation. [PDF] [PUBMED] [DOI] [Abstract...]