2005

Metabolic labelling in proteomics

Beynon RJ, Pratt J.M. (2005) Metabolic labelling of proteins for proteomics. Mol Cell Proteomics. 4, 857-872 [PUBMED] [PDF] [Abstract...]

Proteome dynamics review

Beynon RJ.(2005) The dynamics of the proteome: strategies for measuring protein turnover on a proteome-wide scale. Brief Funct Genomic Proteomic. 3, 382-390 [PUBMED] [PDF] [Abstract...]

First paper on dynamic SILAC in intact animals

Doherty, M.K., Whitehead, C., McCormack, H., Gaskell, S.J. & Beynon, R.J. (2005) Proteome dynamics in complex organisms: using stable isotopes to monitor individual protein turnover rates. Proteomics 5, 522-533 [PUBMED] [PDF] [Abstract...]

Identification of an atypical male-specific MUP in mouse urine

Armstrong, S.D., Robertson, D.H.L., Cheetham, S.A., Hurst, J.L. & Beynon, R.J. (2005) Structural and functional differences in isoforms of Major Urinary Proteins: a male specific protein that preferentially binds a male pheromone. Biochem. J. 391, 343-350 [PUBMED] [PDF] [Abstract...]

Copper toxicity in sheep

Haywood, S. Simpson, D.M, Ross, G. & Beynon, R.J. (2005) The unique response of North Ronaldsay sheep to copper challenge compared with Cambridge sheep: oxidative stress, mitochondrial damage and hepatic stellate cell activation. J. Comp. Path.133, 114-127 [PUBMED] [PDF] [Abstract...]

Characterising proteins in scent marks

Robertson, D.H.L., Cheetham, S.A., Armstrong, S.D., Hurst, J.L. & Beynon, R.J. (2005) Characterisation of proteins in scent marks: proteomics meets semiochemistry. In Chemical Signals in Vertebrates 10 (Ed. R.T. Mason, M.P. LeMaster & D. Muller-Schwarze), pp.183-198 Springer, New York. [Abstract...]

MHC in scent communication

Thom, M.D., Beynon, R.J. & Hurst, J.L. (2005) The role of the major histocompatibility complex in scent communication. In: Chemical Signals in Vertebrates 10 (Ed. R.T. Mason, M.P. LeMaster & D. Muller-Schwarze), pp.173-182. Springer, New York. [Abstract...]

MHC is not involved in individual recognition

Hurst J. L., Thom M. D., Nevison C. M., Humphries R. E., Beynon R. J (2005) MHC odours are not required or sufficient for recognition of individual scent owners. Proc Biol Sci. 272, 715-724 [PUBMED] [PDF] [Abstract...]

Peptide map drawing tool

Beynon, R.J. (2005) A simple tool for drawing proteolytic peptide maps. Bioinformatics 21, 674-675 [PUBMED] [PDF] [Abstract...]

Proteasome proteolysis

Hayter JR, Doherty MK, Whitehead C, McCormack H, Gaskell SJ & Beynon RJ. (2005) The subunit structure and dynamics of the 20S proteasome in chicken skeletal muscle. Mol. Cell. Proteomics. 4, 1370-1381 [PUBMED] [PDF] [Abstract...]

First paper describing QconCAT

Beynon, R.J., Doherty, M.K., Pratt, J.M. & Gaskell, S.J. (2005) Multiplexed absolute quantification in proteomics using artificial QCAT proteins of concatenated signature peptides rates. Nature Methods 2, 587-589 [PUBMED] [PDF [Abstract...]

Scent marks signal competitive ability

Malone, N., Armstrong, S.D., Humphries, R.E., Beynon, R.J. & Hurst, J.L. (2005) The signalling of competitive ability by male house mice. In: Chemical Signals in Vertebrates 10 (Ed. R.T. Mason, M.P. LeMaster & D. Muller-Schwarze), pp.77-88. Springer, New York. [Abstract...]

Lysine acetylation of histones

Fraga, Mario F., Ballestar, Esteban, Villar-Garea, Ana, Boix-Chornet, Manuel, Espada, Jesus, Schotta, Gunnar, Bonaldi, Tiziana, Haydon, Claire, Ropero, Santiago, Petrie, Kevin. 2005. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nature genetics 37: 391-400. [PUBMED] [Abstract...]

CaZIP phosphorylation

Eyers, Claire E., McNeill, Helen, Knebel, Axel, Morrice, Nick, Arthur, Simon J. C., Cuenda, Ana, Cohen, Philip. 2005. The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. Biochemical Journal 389: 127. [PUBMED] [Abstract...]