2011
Oxidative stress and MUPs
Garratt, M., McArdle, F., Stockely, P., Vasilaki, A., Beynon, R.J. Jackson, M.J. & Hurst, J.L. (2011) Tissue dependent changes in oxidative damage with male reproductive effort in house mice. Functional Ecology (in press) [Abstract...]
Asymetric equalisation with combinatorial beads
Jenny Rivers, Chris Hughes, Thérèse McKenna, Yvonne Woolerton, Johannes P. C. Vissers, James I. Langridge and Robert J. Beynon (2011) Asymmetric proteome equalization of the skeletal muscle proteome using a combinatorial hexapeptide library PLOS One (in press)
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Positional proteomics and MetAP-2 substrates
Thomas B. Sundberg, Nicole Darricarrere, Pasquale Cirone, Xia Li, Lucy McDonald, Xue Mei, Christopher J. Westlake, Diane C. Slusarski, Robert J. Beynon, and Craig M. Crews (2011) Disruption of Wnt Planar Cell Polarity Signaling by Aberrant Accumulation of the MetAP-2 Substrate Rab37. (2011)Chemistry & Biology, 18, 1300-1311. doi:10.1016/j.chembiol.2011.07.020 [PUBMED][PDF] [Abstract...]
Enzyme turnover and metabolic regulation
Arden, C, Petrie, J.L., Tudhope, S.J., Al-Oanzi, Z., Claydon, A.J., Beynon, R.J., Towle, H.C. & Agius, L. (2011) Diabetes Journal (in press) Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis [PUBMED][PDF] [Abstract...]
Quantification of a metabolic pathway
Carroll KM, Simpson DM, Eyers CE, Knight CG, Brownridge P, Dunn W, Winder CL, Lanthaler K, Pir P, Malys N, Kell DB, Oliver SG, Gaskell SJ, Beynon RJ. (2011) Absolute quantification of a metabolic pathway in yeast: deployment of a complete QconCAT approach. Mol Cell Proteomics. 2011 Sep 19. [PUBMED][PDF] [Abstract...]
Scent of sensecence
Garratt, .M, Stockely, P., Armstrong, S.D., Beynon, R/J. & Hurst, J.L. (2011) The scent of senescence: sexual signalling and female preference in house mice. J. Evol. Biol [PDF] doi: 10.111111/j.1420-9101.2011.02367.x [Abstract...]
Yeast complex proteomics
Drummond, S., Hildyard, J., Firczuk, H., Reamtong, O., Li, N.,Kannambath, S., Claydon, A., Beynon, R., Eyers, C.E. McCarthy, J.E.G (2011) Diauxic shift-dependent relocalization of decapping activators Dhh1 and Pat1 to polysomal complexes. Nucl Acid Res. [PUBMED][PDF] [Abstract...]
Schistosome parasite QconCAT
Castro-Borgesa, W., Simpson, D.M., Dowlea, A., Curwen, R.S., Thomas-Oates, J., Beynon, R.J. & Wilson, A. R. (2011) Abundance of tegument surface proteins in the human blood fluke Schistosoma mansoni determined by QconCAT proteomics. J Proteomics [PUBMED][PDF] [Abstract...]
Strategies for dynamic SILAC
Claydon, A & Beynon R (2011) Methods Mol Biol. 759, 179-195. Protein Turnover Methods in Single-Celled Organisms: Dynamic SILAC [Abstract...]
The end of proteomics
Davidson GR, Armstrong SD, Beynon R (2011) Methods Mol Biol. 753:229-242. Positional proteomics at the N-terminus as a means of proteome simplification. [PUBMED][PDF]
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Unkind cuts - proteolysis and proteomics
Brownridge, P. & Beynon, R.J. (2011) The importance of the digest: proteolysis and absolute quantification in proteomics. Methods, [PUBMED] [PDF] [Abstract...]
Global proteome quantification: dreams or reality?
Brownridge, P., Holman, S.W., Gaskell, S.J., Grant, C., Harman, V.M., Lanthaler, K., Lawless, C., O’cualain, R., Sims, P., Watkins, R & Beynon, R.J. (2011) Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy. Proteomics, 11, 2957-2970 [PUBMED][PDF] [Abstract...]