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Dr Ingeborg Welters
Prof (apl.) Dr. med.

Publications

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2024

Statistical analysis plan for the biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2) study: An international randomised controlled multicentre trial.

von Groote, T., Danzer, M. F., Meersch, M., Zarbock, A., Gerß, J., & BigpAK-2 study group. (2024). Statistical analysis plan for the biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2) study: An international randomised controlled multicentre trial.. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 26(2), 80-86. doi:10.1016/j.ccrj.2024.03.001

DOI
10.1016/j.ccrj.2024.03.001
Journal article

Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).

Pickkers, P., Angus, D. C., Bass, K., Bellomo, R., van den Berg, E., Bernholz, J., . . . REVIVAL investigators. (2024). Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).. Intensive care medicine, 50(4), 614-615. doi:10.1007/s00134-024-07357-z

DOI
10.1007/s00134-024-07357-z
Journal article

Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.

Vaara, S. T., Serpa Neto, A., Bellomo, R., Adhikari, N. K. J., Dreyfuss, D., Gallagher, M., . . . STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Investigators . (2024). Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.. Critical care explorations, 6(2), e1053. doi:10.1097/cce.0000000000001053

DOI
10.1097/cce.0000000000001053
Journal article

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

RECOVERY Collaborative Group., Horby, P. W., Peto, L., Staplin, N., Campbell, M., Pessoa-Amorim, G., . . . Landray, M. J. (2024). Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.. Nature communications, 15(1), 924. doi:10.1038/s41467-023-43644-x

DOI
10.1038/s41467-023-43644-x
Journal article

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.

RECOVERY Collaborative Group. (2024). Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.. The Lancet. Child & adolescent health, S2352-4642(23)00316-4. doi:10.1016/s2352-4642(23)00316-4

DOI
10.1016/s2352-4642(23)00316-4
Journal article

2023

Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial.

Whitehouse, T., Hossain, A., Perkins, G. D., Gordon, A. C., Bion, J., Young, D., . . . STRESS-L Collaborators. (2023). Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial.. JAMA, 330(17), 1641-1652. doi:10.1001/jama.2023.20134

DOI
10.1001/jama.2023.20134
Journal article

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial.

Wald, R., Gaudry, S., da Costa, B. R., Adhikari, N. K. J., Bellomo, R., Du, B., . . . STARRT-AKI Investigators. (2023). Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial.. Intensive care medicine, 49(11), 1305-1316. doi:10.1007/s00134-023-07211-8

DOI
10.1007/s00134-023-07211-8
Journal article

PIM-COVID study: protocol for a multicentre, longitudinal study measuring the psychological impact of surviving an intensive care admission due to COVID-19 on patients in the UK

Waite, A. A. C., Johnston, B. W., Boyle, A. J., Cherry, M. G., Fisher, P., Brown, S. L., . . . Welters, I. D. (2023). PIM-COVID study: protocol for a multicentre, longitudinal study measuring the psychological impact of surviving an intensive care admission due to COVID-19 on patients in the UK. BMJ OPEN, 13(9). doi:10.1136/bmjopen-2023-071730

DOI
10.1136/bmjopen-2023-071730
Journal article

Metabolomic analysis of exhaled breath can rule out ventilator-associated pneumonia (VAP) in critically ill patients

Ahmed, W., White, I., Van Oort, P., Rattray, N., Docherty, C., Bannard-Smith, J., . . . Fowler, S. (2023). Metabolomic analysis of exhaled breath can rule out ventilator-associated pneumonia (VAP) in critically ill patients. In Molecular pathology and functional genomics (pp. PA2963). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa2963

DOI
10.1183/13993003.congress-2023.pa2963
Conference Paper

Metabolomics of blood plasma from critically ill patients with suspected ventilator-associated pneumonia

Ahmed, W., Burke, A., Gotts, N., Van Oort, P., Bannard-Smith, J., Morton, B., . . . Fowler, S. (2023). Metabolomics of blood plasma from critically ill patients with suspected ventilator-associated pneumonia. In Molecular pathology and functional genomics (pp. PA2962). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa2962

DOI
10.1183/13993003.congress-2023.pa2962
Conference Paper

Study protocol: A systematic review and meta-analysis regarding the influence of coagulopathy and immune activation on new onset atrial fibrillation in patients with sepsis.

Downes, M., Welters, I. D., & Johnston, B. W. (2023). Study protocol: A systematic review and meta-analysis regarding the influence of coagulopathy and immune activation on new onset atrial fibrillation in patients with sepsis.. PloS one, 18(9), e0290963. doi:10.1371/journal.pone.0290963

DOI
10.1371/journal.pone.0290963
Journal article

Who to escalate during a pandemic? A retrospective observational study about decision-making during the COVID-19 pandemic in the UK.

Beresford, S., Tandon, A., Farina, S., Johnston, B., Crews, M., & Welters, I. D. (2023). Who to escalate during a pandemic? A retrospective observational study about decision-making during the COVID-19 pandemic in the UK.. Emergency medicine journal : EMJ, emermed-2022-212505. doi:10.1136/emermed-2022-212505

DOI
10.1136/emermed-2022-212505
Journal article

Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicentre, Randomised, Controlled Trial.

Gorman, E. A., Rynne, J., Gardiner, H. J., Rostron, A. J., Bannard-Smith, J., Bentley, A. M., . . . O'Kane, C. M. (2023). Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicentre, Randomised, Controlled Trial.. American journal of respiratory and critical care medicine. doi:10.1164/rccm.202302-0297oc

DOI
10.1164/rccm.202302-0297oc
Journal article

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Horby, P. W., Emberson, J. R., Basnyat, B., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2023). Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 401(10387), 1499-1507. doi:10.1016/S0140-6736(23)00510-X

DOI
10.1016/S0140-6736(23)00510-X
Journal article

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study.

Pham, T., Heunks, L., Bellani, G., Madotto, F., Aragao, I., Beduneau, G., . . . WEAN SAFE Investigators. (2023). Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study.. The Lancet. Respiratory medicine, 11(5), 465-476. doi:10.1016/s2213-2600(22)00449-0

DOI
10.1016/s2213-2600(22)00449-0
Journal article

Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial.

Bagshaw, S. M., Neto, A. S., Smith, O., Weir, M., Qiu, H., Du, B., . . . STARRT-AKI Investigators. (2023). Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial.. Intensive care medicine, 49(3), 381-383. doi:10.1007/s00134-023-06976-2

DOI
10.1007/s00134-023-06976-2
Journal article

2022

REPAIR OF ACUTE RESPIRATORY DISTRESS SYNDROME IN COVID-19 BY STROMAL CELLS (REALIST-COVID TRIAL): 1 YEAR FOLLOW UP FOR SAFETY AND PULMONARY DYSFUNCTION

Gardiner, H. J., Gorman, E. A., Rostron, A. J., Shankar-Hari, M., Bannard-Smith, J., Bentley, A. M., . . . O'Kane, C. M. (2022). REPAIR OF ACUTE RESPIRATORY DISTRESS SYNDROME IN COVID-19 BY STROMAL CELLS (REALIST-COVID TRIAL): 1 YEAR FOLLOW UP FOR SAFETY AND PULMONARY DYSFUNCTION. In THORAX Vol. 77 (pp. A30). doi:10.1136/thorax-2022-BTSabstracts.50

DOI
10.1136/thorax-2022-BTSabstracts.50
Conference Paper

Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study

Vink, E., Davis, C., MacLean, A., Pascall, D., McDonald, S. E., Gunson, R., . . . Ho, A. (2022). Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study. OPEN FORUM INFECTIOUS DISEASES, 9(11). doi:10.1093/ofid/ofac531

DOI
10.1093/ofid/ofac531
Journal article

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

Horby, P. W., Emberson, J. R., Mafham, M., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2022). Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. LANCET, 400(10349), 359-368. Retrieved from https://www.webofscience.com/

Journal article

PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO protocol for a multicentre, open-label, randomised controlled trial

Euden, J., Thomas-Jones, E., Aston, S., Brookes-Howell, L., Carman, J., Carrol, E., . . . French, N. (2022). PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO protocol for a multicentre, open-label, randomised controlled trial. BMJ OPEN, 12(6). doi:10.1136/bmjopen-2022-063424

DOI
10.1136/bmjopen-2022-063424
Journal article

Development of a Risk Prediction Model for New Episodes of Atrial Fibrillation in Medical-Surgical Critically Ill Patients Using the AmsterdamUMCdb.

Ortega-Martorell, S., Pieroni, M., Johnston, B. W., Olier, I., & Welters, I. D. (2022). Development of a Risk Prediction Model for New Episodes of Atrial Fibrillation in Medical-Surgical Critically Ill Patients Using the AmsterdamUMCdb.. Frontiers in cardiovascular medicine, 9, 897709. doi:10.3389/fcvm.2022.897709

DOI
10.3389/fcvm.2022.897709
Journal article

Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cell Administration (REALIST-COVID) Phase 2 Randomised Controlled Trial

Gorman, E., McAuley, D. F., Rostron, A. J., Shankar-Hari, M., Bannard-Smith, J., Bentley, A. M., . . . O'Kane, C. M. (2022). Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cell Administration (REALIST-COVID) Phase 2 Randomised Controlled Trial. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 205. Retrieved from https://www.webofscience.com/

Conference Paper

A Retrospective Observational Study of Anticoagulation Practices in Critically ill Patients with Atrial Fibrillation Admitted to the Intensive Care Unit

Johnston, B., Miller, N., Welters, I., Waite, A., Hampden-Martin, A., & Waugh, V. (2022). A Retrospective Observational Study of Anticoagulation Practices in Critically ill Patients with Atrial Fibrillation Admitted to the Intensive Care Unit. Journal of Intensive Care Medicine. doi:10.1177/08850666221092997

DOI
10.1177/08850666221092997
Journal article

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial

Bradbury, C. A., Lawler, P. R., Stanworth, S. J., McVerry, B. J., McQuilten, Z., Higgins, A. M., . . . Gordon, A. C. (2022). Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 327(13), 1247-1259. doi:10.1001/jama.2022.2910

DOI
10.1001/jama.2022.2910
Journal article

Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.

Maddali, M. V., Churpek, M., Pham, T., Rezoagli, E., Zhuo, H., Zhao, W., . . . LUNG SAFE Investigators and the ESICM Trials Group. (2022). Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.. The Lancet. Respiratory medicine, 10(4), 367-377. doi:10.1016/s2213-2600(21)00461-6

DOI
10.1016/s2213-2600(21)00461-6
Journal article

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19 The RECOVERY-RS Randomized Clinical Trial

Perkins, G. D., Ji, C., Connolly, B. A., Couper, K., Lall, R., Baillie, J. K., . . . McAuley, D. F. (2022). Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19 The RECOVERY-RS Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 327(6), 546-558. doi:10.1001/jama.2022.0028

DOI
10.1001/jama.2022.0028
Journal article

Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies.

Pisani, L., Algera, A. G., Neto, A. S., Azevedo, L., Pham, T., Paulus, F., . . . PRoVENT-iMiC study investigators. (2022). Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies.. The Lancet. Global health, 10(2), e227-e235. doi:10.1016/s2214-109x(21)00485-x

DOI
10.1016/s2214-109x(21)00485-x
Journal article

Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study.

Enne, V. I., Aydin, A., Baldan, R., Owen, D. R., Richardson, H., Ricciardi, F., . . . INHALE WP1 Study Group. (2022). Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study.. Thorax, 77(12), 1220-1228. doi:10.1136/thoraxjnl-2021-216990

DOI
10.1136/thoraxjnl-2021-216990
Journal article

Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol

Knight, S. R., Gupta, R. K., Ho, A., Pius, R., Buchan, I., Carson, G., . . . Harrison, E. M. (2022). Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. THORAX, 77(6), 606-615. doi:10.1136/thoraxjnl-2021-217629

DOI
10.1136/thoraxjnl-2021-217629
Journal article

2021

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.

Fallerini, C., Picchiotti, N., Baldassarri, M., Zguro, K., Daga, S., Fava, F., . . . Furini, S. (2021). Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.. Human genetics, 141(1), 147-173. doi:10.1007/s00439-021-02397-7

DOI
10.1007/s00439-021-02397-7
Journal article

Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial

Estcourt, L. J., Turgeon, A. F., McQuilten, Z. K., McVerry, B. J., Al-Beidh, F., Annane, D., . . . Shankar-Hari, M. (2021). Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(17), 1690-1702. doi:10.1001/jama.2021.18178

DOI
10.1001/jama.2021.18178
Journal article

Strategies to enhance recruitment and consent to intensive care studies: a qualitative study with researchers and patient-public involvement contributors

Paddock, K., Woolfall, K., Frith, L., Watkins, M., Gamble, C., Welters, I., & Young, B. (2021). Strategies to enhance recruitment and consent to intensive care studies: a qualitative study with researchers and patient-public involvement contributors. BMJ OPEN, 11(9). doi:10.1136/bmjopen-2020-048193

DOI
10.1136/bmjopen-2020-048193
Journal article

Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure The REST Randomized Clinical Trial

McNamee, J. J., Gillies, M. A., Barrett, N. A., Perkins, G. D., Tunnicliffe, W., Young, D., . . . McAuley, D. F. (2021). Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure The REST Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(11), 1013-1023. doi:10.1001/jama.2021.13374

DOI
10.1001/jama.2021.13374
Journal article

Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs

Haas, L. E. M., Boumendil, A., Flaatten, H., Guidet, B., Ibarz, M., Jung, C., . . . de Lange, D. W. (2021). Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs. AGE AND AGEING, 50(5), 1719-1727. doi:10.1093/ageing/afab036

DOI
10.1093/ageing/afab036
Journal article

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

Russell, C. D., Fairfield, C. J., Drake, T. M., Turtle, L., Seaton, R. A., Wootton, D. G., . . . Ho, A. (2021). Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study. LANCET MICROBE, 2(8), E354-E365. doi:10.1016/S2666-5247(21)00090-2

DOI
10.1016/S2666-5247(21)00090-2
Journal article

Pressure injury prediction models for critically-ill patients should consider both the case-mix and local factors.

Deschepper, M., Labeau, S. O., Waegeman, W., Blot, S. I., DecubICUs study Team., & European Society of Intensive Care Medicine (ESICM) Trials Group collaborators. (2021). Pressure injury prediction models for critically-ill patients should consider both the case-mix and local factors.. Intensive & critical care nursing, 65, 103033. doi:10.1016/j.iccn.2021.103033

DOI
10.1016/j.iccn.2021.103033
Journal article

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Semple, M. G. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. LANCET, 398(10296), 223-237. Retrieved from https://www.webofscience.com/

Journal article

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2

DOI
10.1016/S2213-2600(21)00175-2
Journal article

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.

Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., . . . ISARIC4C Investigators. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.. The Lancet. Rheumatology, 3(7), e498-e506. doi:10.1016/s2665-9913(21)00104-1

DOI
10.1016/s2665-9913(21)00104-1
Journal article

Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort

Yates, T., Zaccardi, F., Islam, N., Razieh, C., Gillies, C. L., Lawson, C. A., . . . Khunti, K. (2021). Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort. OBESITY, 29(7), 1223-1230. doi:10.1002/oby.23178

DOI
10.1002/oby.23178
Journal article

Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

Fronczek, J., Polok, K., de Lange, D. W., Jung, C., Beil, M., Rhodes, A., . . . Szczeklik, W. (2021). Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study. CRITICAL CARE, 25(1). doi:10.1186/s13054-021-03632-3

DOI
10.1186/s13054-021-03632-3
Journal article

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

Bloom, C. I., Drake, T. M., Docherty, A. B., Lipworth, B. J., Johnston, S. L., Nguyen-Van-Tam, J. S., . . . Openshaw, P. J. M. (2021). Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 699-711. doi:10.1016/S2213-2600(21)00013-8

DOI
10.1016/S2213-2600(21)00013-8
Journal article

Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study

Pham, T., Pesenti, A., Bellani, G., Rubenfeld, G., Fan, E., Bugedo, G., . . . Laffey, J. G. (2021). Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study. EUROPEAN RESPIRATORY JOURNAL, 57(6). doi:10.1183/13993003.03317-2020

DOI
10.1183/13993003.03317-2020
Journal article

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.

Labeau, S. O., Afonso, E., Benbenishty, J., Blackwood, B., Boulanger, C., Brett, S. J., . . . European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators. (2021). Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.. Intensive care medicine, 47(4), 503-520. doi:10.1007/s00134-020-06327-5

DOI
10.1007/s00134-020-06327-5
Journal article

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Noursadeghi, M. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. LANCET RESPIRATORY MEDICINE, 9(4), 349-359. doi:10.1016/S2213-2600(20)30559-2

DOI
10.1016/S2213-2600(20)30559-2
Journal article

Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial

Shehabi, Y., Neto, A. S., Howe, B. D., Bellomo, R., Arabi, Y. M., Bailey, M., . . . Webb, S. A. (2021). Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial. INTENSIVE CARE MEDICINE, 47(4), 455-466. doi:10.1007/s00134-021-06356-8

DOI
10.1007/s00134-021-06356-8
Journal article

Retraction notice to “Normothermic versus hypothermic cardiopulmonary bypass: do changes in coagulation differ?” [ 62 (1996) 130-135]

Boldt, J., Knothe, C., Welters, I., Dapper, F. L., & Hempelmann, G. (2021). Retraction notice to “Normothermic versus hypothermic cardiopulmonary bypass: do changes in coagulation differ?” [ 62 (1996) 130-135]. The Annals of Thoracic Surgery, 111(3), e229. doi:10.1016/j.athoracsur.2021.01.004

DOI
10.1016/j.athoracsur.2021.01.004
Journal article

Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.

Sakr, Y., François, B., Solé-Violan, J., Kotfis, K., Jaschinski, U., Estella, A., . . . SOAP and ICON Investigators. (2021). Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.. Critical care (London, England), 25(1), 87. doi:10.1186/s13054-020-03455-8

DOI
10.1186/s13054-020-03455-8
Journal article

Point of care ultrasound in acutely breathless patients-A qualitative study of the enablers and challenges in a teaching hospital in Kenya

Kagima, J. W., Masheti, S. A., Mbaiyani, C. W., Munubi, A. Z., Ringwald, B., Meme, H. K., . . . Rylance, J. (n.d.). Point of care ultrasound in acutely breathless patients-A qualitative study of the enablers and challenges in a teaching hospital in Kenya. Journal of the Pan African Thoracic Society, 2, 130-139. doi:10.25259/jpats_24_2021

DOI
10.25259/jpats_24_2021
Journal article

Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill peoble aged 65 and over; the 65 RCT

Mouncey, P. R., Richards-Belle, A., Thomas, K., Harrison, D. A., Sadique, M. Z., Grieve, R. D., . . . Rowan, K. M. (2021). Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill peoble aged 65 and over; the 65 RCT. HEALTH TECHNOLOGY ASSESSMENT, 25(14), I-+. doi:10.3310/hta25140

DOI
10.3310/hta25140
Journal article

2020

Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom

DOI
10.1101/2020.11.10.20226688
Preprint

Letter by Hamilton et al Regarding Article, "Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients"

Hamilton, D. O., Waite, A. A. C., & Welters, I. D. (2020). Letter by Hamilton et al Regarding Article, "Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients". ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 40(11), E309-E310. doi:10.1161/ATVBAHA.120.315235

DOI
10.1161/ATVBAHA.120.315235
Journal article

Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020

Thompson, C. P., Grayson, N. E., Paton, R. S., Bolton, J. S., Lourenco, J., Penman, B. S., . . . Simmonds, P. (2020). Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020. EUROSURVEILLANCE, 25(42), 33-41. doi:10.2807/1560-7917.ES.2020.25.42.2000685

DOI
10.2807/1560-7917.ES.2020.25.42.2000685
Journal article

Does the type of volume therapy influence endothelial-related coagulation in the critically ill? (Retraction of Vol 75, Pg 740, 1995)

Boldt, J., Heesen, M., Welters, I., Padberg, W., Martin, K., & Hempelmann, G. (2020). Does the type of volume therapy influence endothelial-related coagulation in the critically ill? (Retraction of Vol 75, Pg 740, 1995). BRITISH JOURNAL OF ANAESTHESIA, 125(3), 415. doi:10.1016/j.bja.2020.07.034

DOI
10.1016/j.bja.2020.07.034
Journal article

More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia

Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N., Morris, A. C., Singh, S., . . . Simpson, A. J. (2020). More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia. ANNALS OF TRANSLATIONAL MEDICINE, 8(13). doi:10.21037/atm-20-3701

DOI
10.21037/atm-20-3701
Journal article

Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study

Ackland, G. L., Abbott, T. E. F., Jones, T. F., Leuwer, M., & Pearse, R. M. (2020). Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study. BRITISH JOURNAL OF ANAESTHESIA, 124(5), 535-543. doi:10.1016/j.bja.2020.02.003

DOI
10.1016/j.bja.2020.02.003
Journal article

Multiple organ dysfunction after trauma

Cole, E., Gillespie, S., Vulliamy, P., Brohi, K., Akkad, H., Apostolidou, K., . . . Welters, I. (2020). Multiple organ dysfunction after trauma. BRITISH JOURNAL OF SURGERY, 107(4), 402-412. doi:10.1002/bjs.11361

DOI
10.1002/bjs.11361
Journal article

A novel assay of neutrophil extracellular trap (NET) formation identifies anti-IL-8 therapies to reduce disseminated intravascular coagulation and mortality in the intensive care unit.

Abrams, S., Morton, B., Alhamdi, Y., Alsabani, M., Cheng, Z., Lane, S., . . . Toh, C. -H. (2020). A novel assay of neutrophil extracellular trap (NET) formation identifies anti-IL-8 therapies to reduce disseminated intravascular coagulation and mortality in the intensive care unit.. Clinical medicine (London, England), 20(Suppl 2), s114-s115. doi:10.7861/clinmed.20-2-s114

DOI
10.7861/clinmed.20-2-s114
Journal article

The whole blood phagocytosis assay: a clinically relevant test of neutrophil function and dysfunction in community-acquired pneumonia

DOI
10.21203/rs.2.24645/v1
Preprint

Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

Hellyer, T. P., McAuley, D. F., Walsh, T. S., Anderson, N., Morris, A. C., Singh, S., . . . Simpson, A. J. (2020). Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation. LANCET RESPIRATORY MEDICINE, 8(2), 182-191. doi:10.1016/S2213-2600(19)30367-4

DOI
10.1016/S2213-2600(19)30367-4
Journal article

The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study

Guidet, B., de Lange, D. W., Boumendil, A., Leaver, S., Watson, X., Boulanger, C., . . . Flaatten, H. (2020). The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. INTENSIVE CARE MEDICINE, 46(1), 57-69. doi:10.1007/s00134-019-05853-1

DOI
10.1007/s00134-019-05853-1
Journal article

2019

A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies

Abrams, S. T., Morton, B., Alhamdi, Y., Alsabani, M., Cheng, Z., Lane, S., . . . Toh, C. -H. (2019). A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies. In BLOOD Vol. 134. Retrieved from https://www.webofscience.com/

Conference Paper

Protocol for a systematic review and network meta-analysis of the management of new onset atrial fibrillation in critically unwell adult patients

Johnston, B. W., Hill, R., Duarte, R., Chean, C. S., McAuley, D. F., Blackwood, B., . . . Welters, I. D. (2019). Protocol for a systematic review and network meta-analysis of the management of new onset atrial fibrillation in critically unwell adult patients. SYSTEMATIC REVIEWS, 8(1). doi:10.1186/s13643-019-1149-7

DOI
10.1186/s13643-019-1149-7
Journal article

A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients

Abrams, S. T., Morton, B., Alhamdi, Y., Alsabani, M., Lane, S., Welters, I. D., . . . Toh, C. -H. (2019). A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients. American journal of respiratory and critical care medicine, 200(07), 869-880. doi:10.1164/rccm.201811-2111oc

DOI
10.1164/rccm.201811-2111oc
Journal article

Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study

McNicholas, B. A., Rezoagli, E., Pham, T., Madotto, F., Guiard, E., Fanelli, V., . . . Laffey, J. G. (2019). Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study. CRITICAL CARE MEDICINE, 47(9), 1216-1225. doi:10.1097/CCM.0000000000003832

DOI
10.1097/CCM.0000000000003832
Journal article

Early Sedation with Dexmedetomidine in Critically Ill Patients

Shehabi, Y., Howe, B. D., Bellomo, R., Arabi, Y. M., Bailey, M., Bass, F. E., . . . Webb, S. A. (2019). Early Sedation with Dexmedetomidine in Critically Ill Patients. NEW ENGLAND JOURNAL OF MEDICINE, 380(26), 2506-2517. doi:10.1056/NEJMoa1904710

DOI
10.1056/NEJMoa1904710
Journal article

Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial

Peden, C. J., Stephens, T., Martin, G., Kahan, B. C., Thomson, A., Rivett, K., . . . Pearse, R. M. (2019). Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial. LANCET, 393(10187), 2213-2221. doi:10.1016/S0140-6736(18)32521-2

DOI
10.1016/S0140-6736(18)32521-2
Journal article

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET Randomized Clinical Trial

Vincent, J. -L., Francois, B., Zabolotskikh, I., Daga, M. K., Lascarrou, J. -B., Kirov, M. Y., . . . Kayanoki, T. (2019). Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 321(20), 1993-2002. doi:10.1001/jama.2019.5358

DOI
10.1001/jama.2019.5358
Journal article

The influence of acute preoperative plasmapheresis on coagulation tests, fibrinolysis, blood loss and transfusion requirements in cardiac surgery (Retraction of Vol 11, Pg 557, 1997)

Menges, T., Welters, I., Wagner, R. -M., Boldt, J., Dapper, F., & Hempelmann, G. (2019). The influence of acute preoperative plasmapheresis on coagulation tests, fibrinolysis, blood loss and transfusion requirements in cardiac surgery (Retraction of Vol 11, Pg 557, 1997). EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 55(5), 1024. doi:10.1093/ejcts/ezz079

DOI
10.1093/ejcts/ezz079
Journal article

Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome Insights from the LUNG SAFE Study

Tai, P., Neto, A. S., Pelosi, P., Laffey, J. G., De Haro, C., Angel Lorente, J., . . . Veljovic, M. (2019). Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome Insights from the LUNG SAFE Study. ANESTHESIOLOGY, 130(2), 263-283. doi:10.1097/ALN.0000000000002508

DOI
10.1097/ALN.0000000000002508
Journal article

Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study*

van Haren, F., Pham, T., Brochard, L., Bellani, G., Laffey, J., Dres, M., . . . McAuley, D. (2019). Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study*. CRITICAL CARE MEDICINE, 47(2), 229-238. doi:10.1097/CCM.0000000000003519

DOI
10.1097/CCM.0000000000003519
Journal article

2018

A survey of current attitudes to diaphragm ultrasound in the prediction of successful respiratory weaning.

Turton, P., & Welters, I. D. M. (2018). A survey of current attitudes to diaphragm ultrasound in the prediction of successful respiratory weaning.. Poster session presented at the meeting of Unknown Conference.

Poster

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Boyle, A. J., Madotto, F., Laffey, J. G., Bellani, G., Tai, P., Pesenti, A., . . . McAuley, D. F. (2018). Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database. CRITICAL CARE, 22. doi:10.1186/s13054-018-2158-y

DOI
10.1186/s13054-018-2158-y
Journal article

Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

Calfee, C. S., Delucchi, K. L., Sinha, P., Matthay, M. A., Hackett, J., Shankar-Hari, M., . . . McAuley, D. F. (2018). Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. LANCET RESPIRATORY MEDICINE, 6(9), 691-698. doi:10.1016/S2213-2600(18)30177-2

DOI
10.1016/S2213-2600(18)30177-2
Journal article

Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

Madotto, F., Tai, P., Bellani, G., Bos, L. D., Simonis, F. D., Fan, E., . . . Laffey, J. G. (2018). Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study. INTENSIVE CARE MEDICINE, 44(5), 564-577. doi:10.1007/s00134-018-5152-6

DOI
10.1007/s00134-018-5152-6
Journal article

Angiotensin II for the Treatment of Vasodilatory Shock

Hemmy, D. (2018). Angiotensin II for the Treatment of Vasodilatory Shock. The Journal of Emergency Medicine, 54(1), 138-139. doi:10.1016/j.jemermed.2017.11.005

DOI
10.1016/j.jemermed.2017.11.005
Journal article

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (vol 42, pg 1865, 2016)

Laffey, J. G., Bellani, G., Pham, T., Fan, E., Madotto, F., Bajwa, E. K., . . . Pesenti, A. (2018). Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (vol 42, pg 1865, 2016). INTENSIVE CARE MEDICINE, 44(1), 157-165. doi:10.1007/s00134-017-4981-z

DOI
10.1007/s00134-017-4981-z
Journal article

2017

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study

Laffey, J. G., Madotto, F., Bellani, G., Pham, T., Fan, E., Brochard, L., . . . Pesenti, A. (2017). Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study. LANCET RESPIRATORY MEDICINE, 5(8), 627-638. doi:10.1016/S2213-2600(17)30213-8

DOI
10.1016/S2213-2600(17)30213-8
Journal article

37th International Symposium on Intensive Care and Emergency Medicine (part 2 of 3)

Rob, D., Špunda, R., Lindner, J., Šmalcová, J., Šmíd, O., Kovárník, T., . . . Doyle, B. (2017). 37th International Symposium on Intensive Care and Emergency Medicine (part 2 of 3). Critical Care, 21(S1). doi:10.1186/s13054-017-1630-4

DOI
10.1186/s13054-017-1630-4
Journal article

37th International Symposium on Intensive Care and Emergency Medicine (part 3 of 3)

Von Seth, M., Hillered, L., Otterbeck, A., Hanslin, K., Larsson, A., Sjölin, J., . . . O’Flynn, J. (2017). 37th International Symposium on Intensive Care and Emergency Medicine (part 3 of 3). Critical Care, 21(S1). doi:10.1186/s13054-017-1629-x

DOI
10.1186/s13054-017-1629-x
Journal article

Elevated Circulating Histones Associate With Multiple Organ Dysfunction Syndromes in Acute Pancreatitis

Liu, T., Huang, W., Abrams, S., Wang, L., Szatmary, P., Alhamdi, Y., . . . Sutton, R. (2016). Elevated Circulating Histones Associate With Multiple Organ Dysfunction Syndromes in Acute Pancreatitis. PANCREAS, 45(10), 1520. Retrieved from https://www.webofscience.com/

Journal article

Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit

Sakr, Y., Birri, P. N. R., Kotfis, K., Nanchal, R., Shah, B., Kluge, S., . . . Vincent, J. -L. (2017). Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit. CRITICAL CARE MEDICINE, 45(3), 386-394. doi:10.1097/CCM.0000000000002189

DOI
10.1097/CCM.0000000000002189
Journal article

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome Insights from the LUNG SAFE Study

Bellani, G., Laffey, J. G., Tai, P., Madotto, F., Fan, E., Brochard, L., . . . Pesenti, A. (2017). Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome Insights from the LUNG SAFE Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195(1), 67-77. doi:10.1164/rccm.201606-1306OC

DOI
10.1164/rccm.201606-1306OC
Journal article

2016

Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care - an observational study using ultrasound

Turton, P., Hay, R., Taylor, J., McPhee, J., & Welters, I. (2016). Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care - an observational study using ultrasound. BMC ANESTHESIOLOGY, 16. doi:10.1186/s12871-016-0269-z

DOI
10.1186/s12871-016-0269-z
Journal article

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study.

Neto, A. S., Barbas, C. S. V., Simonis, F. D., Artigas-Raventós, A., Canet, J., Determann, R. M., . . . PROVE Network investigators. (2016). Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study.. The Lancet. Respiratory medicine, 4(11), 882-893. doi:10.1016/s2213-2600(16)30305-8

DOI
10.1016/s2213-2600(16)30305-8
Journal article

ESICM LIVES 2016: part one: Milan, Italy. 1-5 October 2016.

Bos, L., Schouten, L., van Vught, L., Wiewel, M., Ong, D., Cremer, O., . . . Weber, V. (2016). ESICM LIVES 2016: part one: Milan, Italy. 1-5 October 2016.. Intensive care medicine experimental, 4(Suppl 1), 1-203. doi:10.1186/s40635-016-0098-x

DOI
10.1186/s40635-016-0098-x
Journal article

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

Bellani, G., Laffey, J. G., Pham, T., Fan, E., Brochard, L., Esteban, A., . . . Pesenti, A. (2016). Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA: Journal of the American Medical Association, 315(8), 788-800. doi:10.1001/jama.2016.0291

DOI
10.1001/jama.2016.0291
Journal article

Early prediction of major clinical outcomes of patients with acute pancreatitis by circulating histones

Liu, T., Huang, W., Szatmary, P., Abrams, S. T., Greenhalf, W., Welters, I., . . . Toh, C. H. (2016). Early prediction of major clinical outcomes of patients with acute pancreatitis by circulating histones. Pancreatology, 16(1), S34. doi:10.1016/j.pan.2015.12.107

DOI
10.1016/j.pan.2015.12.107
Journal article

2015

Lipopolysaccharide induces a downregulation of adiponectin receptors in-vitro and in-vivo

Hall, A., Leuwer, M., Trayhurn, P., & Welters, I. D. (2015). Lipopolysaccharide induces a downregulation of adiponectin receptors in-vitro and in-vivo. PEERJ, 3. doi:10.7717/peerj.1428

DOI
10.7717/peerj.1428
Journal article

Exploring the translational disconnect between the murine and human inflammatory response: analysis of LPS dose-response relationship in murine versus human cell lines and implications for translation into murine models of sepsis.

McCarron, E. P., Williams, D. P., Antoine, D. J., Kipar, A., Lemm, J., Stehr, S., & Welters, I. D. (2015). Exploring the translational disconnect between the murine and human inflammatory response: analysis of LPS dose-response relationship in murine versus human cell lines and implications for translation into murine models of sepsis.. Journal of Inflammation Research, 8, 201-209. doi:10.2147/JIR.S89097

DOI
10.2147/JIR.S89097
Journal article

The effect of the anticoagulation regimen on endothelial-related coagulation in cardiac surgery patients (Retraction of vol 50, pg 954, 1995)

Boldt, J., Schindler, E., Welters, I., Wittstock, M., Stertmann, W. A., & Hempelmann, G. (2015). The effect of the anticoagulation regimen on endothelial-related coagulation in cardiac surgery patients (Retraction of vol 50, pg 954, 1995). ANAESTHESIA, 70(9), 1104. doi:10.1111/anae.13188

DOI
10.1111/anae.13188
Journal article

CONFOCAL ENDOMICROSCOPY DEMONSTRATES INCREASED INTESTINAL PERMEABILITY AND GUT DYSFUNCTION IN PATIENTS WITH ACUTE AND CHRONIC PANCREATITIS

Bharucha, S., Geraghty, J., Duckworth, C., Armstrong, J., Szatmary, P., Winn, S., . . . Sutton, R. (2015). CONFOCAL ENDOMICROSCOPY DEMONSTRATES INCREASED INTESTINAL PERMEABILITY AND GUT DYSFUNCTION IN PATIENTS WITH ACUTE AND CHRONIC PANCREATITIS. In GUT Vol. 64 (pp. A307). doi:10.1136/gutjnl-2015-309861.663

DOI
10.1136/gutjnl-2015-309861.663
Conference Paper

Circulating histones contribute to acute respiratory distress syndrome in acute pancreatitis

Liu, T., Abrams, S., Szatmary, P., Cheng, Z., Huang, W., Ou, X., . . . Toh, C. -H. (2015). Circulating histones contribute to acute respiratory distress syndrome in acute pancreatitis. Pancreatology, 15(3), S63. doi:10.1016/j.pan.2015.05.242

DOI
10.1016/j.pan.2015.05.242
Journal article

Performance of influenza-specific triage tools in an H1N1-positive cohort: P/F ratio better predicts the need for mechanical ventilation and critical care admission

Morton, B., Tang, L., Gale, R., Kelly, M., Robertson, H., Mogk, M., . . . Welters, I. (2015). Performance of influenza-specific triage tools in an H1N1-positive cohort: P/F ratio better predicts the need for mechanical ventilation and critical care admission. British Journal of Anaesthesia, 114(6), 927-933. doi:10.1093/bja/aev042

DOI
10.1093/bja/aev042
Journal article

760 Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis

Bharucha, S., Geraghty, J., Duckworth, C. A., Armstrong, J., Szatmary, P., Winn, S. A., . . . Sutton, R. (2015). 760 Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis. Gastroenterology, 148(4), S-145. doi:10.1016/s0016-5085(15)30495-9

DOI
10.1016/s0016-5085(15)30495-9
Journal article

Equipment-related critical incidents in a general intensive care unit

King, A. T., Wenstone, R., Morrison, J., Cloherty, L., & Welters, I. D. (2015). Equipment-related critical incidents in a general intensive care unit. Intensive Care Medicine Experimental, 3(S1). doi:10.1186/2197-425x-3-s1-a70

DOI
10.1186/2197-425x-3-s1-a70
Journal article

Low serum phosphate is not diagnostic for refeeding syndrome in critical care

Venugopal, N., Turner, P., Kolamunnage-Dono, R., Downey, C., & Welters, I. D. (2015). Low serum phosphate is not diagnostic for refeeding syndrome in critical care. Intensive Care Medicine Experimental, 3(S1). doi:10.1186/2197-425x-3-s1-a282

DOI
10.1186/2197-425x-3-s1-a282
Journal article

2014

Myocardial Injury after Noncardiac Surgery A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes

Botto, F., Alonso-Coello, P., Chan, M. T. V., Carlos Villar, J., Xavier, D., Srinathan, S., . . . Wildes, T. (2014). Myocardial Injury after Noncardiac Surgery A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes. ANESTHESIOLOGY, 120(3), 564-578. doi:10.1097/ALN.0000000000000113

DOI
10.1097/ALN.0000000000000113
Journal article

Circulating anti-inflammatory adipokines High Molecular Weight Adiponectin and Zinc-α2-glycoprotein (ZAG) are inhibited in early sepsis, but increase with clinical recovery: a pilot study

Welters, I. D., Bing, C., Ding, C., Leuwer, M., & Hall, A. M. (2014). Circulating anti-inflammatory adipokines High Molecular Weight Adiponectin and Zinc-α2-glycoprotein (ZAG) are inhibited in early sepsis, but increase with clinical recovery: a pilot study. BMC ANESTHESIOLOGY, 14. doi:10.1186/1471-2253-14-124

DOI
10.1186/1471-2253-14-124
Journal article

Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients: Validation of a specific anti-M6G antibody for clinical and basic research

Laux-Biehlmann, A., Chung, H., Mouheiche, J., Veriepe, J., Delalande, F., Lamshoeft, M., . . . Garnero, P. (2014). Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients: Validation of a specific anti-M6G antibody for clinical and basic research. BIOFACTORS, 40(1), 113-120. doi:10.1002/biof.1107

DOI
10.1002/biof.1107
Journal article

2013

Assessment and clinical course of hypocalcemia in critical illness

Steele, T., Kolamunnage-Dona, R., Downey, C., Toh, C. -H., & Welters, I. (2013). Assessment and clinical course of hypocalcemia in critical illness. CRITICAL CARE, 17(3). doi:10.1186/cc12756

DOI
10.1186/cc12756
Journal article

Intensive care admission after cardiac arrest: cardiac versus noncardiac causes and consequences for treatment

Hargreaves, T., Kingston, H., Crews, M., Mogk, M., & Welters, I. (2013). Intensive care admission after cardiac arrest: cardiac versus noncardiac causes and consequences for treatment. Critical Care, 17(S2). doi:10.1186/cc12245

DOI
10.1186/cc12245
Journal article

Correspondence Regarding: BIS Monitoring in Intensive Care

Hampshire, P. A., Guha, A. K., Poole, L. A., Welters, I. D., & Murphy, J. (2013). Correspondence Regarding: BIS Monitoring in Intensive Care. Journal of the Intensive Care Society, 14(4), 366-367. doi:10.1177/175114371301400428

DOI
10.1177/175114371301400428
Journal article

Exploring the translational disconnect between the murine and human inflammatory response: analysis of the dose-response relationship of LPS and NFκB activation in murine and human immune cells.

McCarron, E. P., Welters, I., Williams, D., Antoine, D., & Kipar, A. (2013). Exploring the translational disconnect between the murine and human inflammatory response: analysis of the dose-response relationship of LPS and NFκB activation in murine and human immune cells.. Critical care (London, England), 17(Suppl 2), P18. doi:10.1186/cc11956

DOI
10.1186/cc11956
Journal article

2012

Comparison of serum and lithium-heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations

Laux-Biehlmann, A., Graefe, N., Mouheiche, J., Stuber, D., Welters, I. D., Delalande, F., . . . Goumon, Y. (2012). Comparison of serum and lithium-heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 74(2), 381-383. doi:10.1111/j.1365-2125.2012.04199.x

DOI
10.1111/j.1365-2125.2012.04199.x
Journal article

Association Between Postoperative Troponin Levels and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery (vol 307, pg 2295, 2012)

Devereaux, P. J. (2012). Association Between Postoperative Troponin Levels and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery (vol 307, pg 2295, 2012). JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 307(24), 2590. doi:10.1001/jama.2012.6889

DOI
10.1001/jama.2012.6889
Journal article

Error in Viewpoint in: Statin Therapy for Healthy Men Identified as ‘Increased Risk,’

Error in Viewpoint in: Statin Therapy for Healthy Men Identified as ‘Increased Risk,’ (2012). JAMA, 307(24), 2590. doi:10.1001/jama.2012.6832

DOI
10.1001/jama.2012.6832
Journal article

Outcome of faecal peritonitis in the ICU

Sayer, J., Simpson, G., Mccrossan, L., & Welters, I. (2012). Outcome of faecal peritonitis in the ICU. Critical Care, 16(S1). doi:10.1186/cc11005

DOI
10.1186/cc11005
Journal article

Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.

Vascular Events In Noncardiac Surgery Patients Cohort Evaluation., Devereaux, P. J., Chan, M. T., Alonso-Coello, P., Walsh, M., Berwanger, O., . . . Yusuf, S. (2012). Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.. JAMA, 307(21), 2295-2304.

Journal article

Liver failure secondary to alcoholic liver disease carries a worse prognosis than other aetiologies of liver failure: retrospective analysis of routine biochemical markers in critically ill patients with liver failure

McCarron, E., & Welters, I. (2012). Liver failure secondary to alcoholic liver disease carries a worse prognosis than other aetiologies of liver failure: retrospective analysis of routine biochemical markers in critically ill patients with liver failure. Critical care (London, England), 16(Suppl 1), P391. doi:10.1186/cc10998

DOI
10.1186/cc10998
Journal article

Outcome of faecal peritonitis in the ICU

Sayer, J., Simpson, G., Mccrossan, L., & Welters, I. (2012). Outcome of faecal peritonitis in the ICU. Critical care (London, England), 16(Suppl 1), P398.

Journal article

2011

Major sources of critical incidents in intensive care

Welters, I. D., Gibson, J., Mogk, M., & Wenstone, R. (2011). Major sources of critical incidents in intensive care. CRITICAL CARE, 15(5). doi:10.1186/cc10474

DOI
10.1186/cc10474
Journal article

The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

Perez-Casal, M., Thompson, V., Downey, C., Welters, I., Wyncoll, D., Thachil, J., & Toh, C. H. (2011). The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis. CRITICAL CARE, 15(4). doi:10.1186/cc10356

DOI
10.1186/cc10356
Journal article

Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production

Mathioudakis, D., Engel, J., Welters, I. D., Dehne, M. G., Matejec, R., Harbach, H., . . . Muhling, J. (2011). Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production. AMINO ACIDS, 40(4), 1077-1090. doi:10.1007/s00726-010-0731-z

DOI
10.1007/s00726-010-0731-z
Journal article

Continuous <i>S</i>-(+)- ketamine administration during elective coronary artery bypass graft surgery attenuates pro-inflammatory cytokine response during and after cardiopulmonary bypass

Welters, I. D., Feurer, M. -K., Preiss, V., Mueller, M., Scholz, S., Kwapisz, M., . . . Neuhaeuser, C. (2011). Continuous <i>S</i>-(+)- ketamine administration during elective coronary artery bypass graft surgery attenuates pro-inflammatory cytokine response during and after cardiopulmonary bypass. BRITISH JOURNAL OF ANAESTHESIA, 106(2), 172-179. doi:10.1093/bja/aeq341

DOI
10.1093/bja/aeq341
Journal article

Hemodynamic Actions of Corticotropin-Releasing Hormone and Proopiomelanocortin Derivatives in Septic Patients

Matejec, R., Loecke, G., Kayser, F., Lichtenstern, C., Weigand, M. A., Welters, I. D., . . . Harbach, H. -W. (2011). Hemodynamic Actions of Corticotropin-Releasing Hormone and Proopiomelanocortin Derivatives in Septic Patients. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 57(1), 94-102. doi:10.1097/FJC.0b013e3181fffe00

DOI
10.1097/FJC.0b013e3181fffe00
Journal article

Reply from the authors

Welters, I. D., & Neuhäuser, C. (2011). Reply from the authors. British Journal of Anaesthesia, 107(5), 813-814. doi:10.1093/bja/aer321

DOI
10.1093/bja/aer321
Journal article

The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

Pérez-Casal, M., Thompson, V., Downey, C., Welters, I., Wyncoll, D., Thachil, J., & Toh, C. H. (n.d.). The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis. Critical Care, 15(4). doi:10.1186/cc10356

DOI
10.1186/cc10356
Journal article

2010

Ketamine Inhibits Transcription Factors Activator Protein 1 and Nuclear Factor-κB, Interleukin-8 Production, as well as CD11b and CD16 Expression: Studies in Human Leukocytes and Leukocytic Cell Lines

Welters, I. D., Hafer, G., Menzebach, A., Muehling, J., Neuhaeuser, C., Browning, P., & Goumon, Y. (2010). Ketamine Inhibits Transcription Factors Activator Protein 1 and Nuclear Factor-κB, Interleukin-8 Production, as well as CD11b and CD16 Expression: Studies in Human Leukocytes and Leukocytic Cell Lines. ANESTHESIA AND ANALGESIA, 110(3), 934-941. doi:10.1213/ANE.0b013e3181c95cfa

DOI
10.1213/ANE.0b013e3181c95cfa
Journal article

Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils

Glattard, E., Welters, I. D., Lavaux, T., Muller, A. H., Laux, A., Zhang, D., . . . Goumon, Y. (2010). Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils. PLOS ONE, 5(1). doi:10.1371/journal.pone.0008791

DOI
10.1371/journal.pone.0008791
Journal article

Effects of α-ketoglutarate on neutrophil intracellular amino and α-keto acid profiles and ROS production

Muehling, J., Tussing, F., Nickolaus, K. A., Matejec, R., Henrich, M., Harbach, H., . . . Heidt, M. C. (2010). Effects of α-ketoglutarate on neutrophil intracellular amino and α-keto acid profiles and ROS production. AMINO ACIDS, 38(1), 167-177. doi:10.1007/s00726-008-0224-5

DOI
10.1007/s00726-008-0224-5
Journal article

LB035 NUTRITION AND TRACE ELEMENTS IN INTENSIVE CARE UNIT ACQUIRED WEAKNESS

Strang, R., Turner, P., Shenkin, A., Mogk, M., & Welters, I. (2010). LB035 NUTRITION AND TRACE ELEMENTS IN INTENSIVE CARE UNIT ACQUIRED WEAKNESS. Clinical Nutrition Supplements, 5(2), 208-209. doi:10.1016/s1744-1161(10)70547-0

DOI
10.1016/s1744-1161(10)70547-0
Journal article

2009

Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery*

Kwapisz, M. M., Neuhaeuser, C., Scholz, S., Welters, I. D., Loehr, T., Koch, T., . . . Mueller, M. (2009). Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery*. PEDIATRIC ANESTHESIA, 19(9), 862-871. doi:10.1111/j.1460-9592.2009.03101.x

DOI
10.1111/j.1460-9592.2009.03101.x
Journal article

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice

Leuwer, M., Welters, I., Marx, G., Rushton, A., Bao, H., Hunter, L., & Trayhurn, P. (2009). Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice. Pflügers Archiv - European Journal of Physiology, 457(4), 731-741. doi:10.1007/s00424-008-0564-8

DOI
10.1007/s00424-008-0564-8
Journal article

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice

Leuwer, M., Welters, I., Marx, G., Rushton, A., Bao, H., Hunter, L., & Trayhurn, P. (2009). Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 457(4), 731-741. doi:10.1007/s00424-008-0564-8

DOI
10.1007/s00424-008-0564-8
Journal article

Chapter 10 General anesthetics and therapeutic gases

Welters, I. D., & Leuwer, M. (2009). Chapter 10 General anesthetics and therapeutic gases. In Unknown Book (Vol. 31, pp. 217-229). Elsevier. doi:10.1016/s0378-6080(09)03110-9

DOI
10.1016/s0378-6080(09)03110-9
Chapter

General anesthetics and therapeutic gases

Welters, I. D., & Leuwer, M. (2009). General anesthetics and therapeutic gases. In SIDE EFFECTS OF DRUGS ANNUAL: A WORLDWIDE YEARLY SURVEY OF NEW DATA AND TRENDS IN ADVERSE DRUG REACTIONS (Vol. 31, pp. 217-229). doi:10.1016/S0378-6080(09)03110-9

DOI
10.1016/S0378-6080(09)03110-9
Chapter

Intracellular alpha-keto acid quantification by fluorescence-HPLC

Fuchs, M., Engel, J., Campos, M., Matejec, R., Henrich, M., Harbach, H., . . . Muehling, J. (2009). Intracellular alpha-keto acid quantification by fluorescence-HPLC. AMINO ACIDS, 36(1), 1-11. doi:10.1007/s00726-008-0033-x

DOI
10.1007/s00726-008-0033-x
Journal article

2008

Can biochemical markers be used to predict the rate of achieving tight glycaemic control in critically ill adults?

Turner, P., Sanusi, A., Perry, B., Shenkin, A., & Welters, I. (2008). Can biochemical markers be used to predict the rate of achieving tight glycaemic control in critically ill adults?. Proceedings of the Nutrition Society, 67(OCE3). doi:10.1017/s0029665100591356

DOI
10.1017/s0029665100591356
Journal article

Can biochemical markers be used to predict the rate of achieving tight glycaemic control in critically ill adults?

Turner, P., Sanusi, A., Perry, B., Shenkin, A., & Welters, I. (2008). Can biochemical markers be used to predict the rate of achieving tight glycaemic control in critically ill adults?. Proceedings of the Nutrition Society, 67(OCE3). doi:10.1017/s0029665108007829

DOI
10.1017/s0029665108007829
Journal article

Which mechanisms are involved in taurine-dependent granulocytic immune response or amino- and α-keto acid homeostasis?

Muelling, J., Nickolaus, K. A., Matejec, R., Langefeld, T. W., Harbach, H., Engel, J., . . . Hempelmann, G. (2008). Which mechanisms are involved in taurine-dependent granulocytic immune response or amino- and α-keto acid homeostasis?. AMINO ACIDS, 34(2), 257-270. doi:10.1007/s00726-007-0497-0

DOI
10.1007/s00726-007-0497-0
Journal article

10 General anesthetics and therapeutic gases

Welters, I. D., & Leuwer, M. (2008). 10 General anesthetics and therapeutic gases. In Side Effects of Drugs Annual (Vol. 30, pp. 137-151). doi:10.1016/S0378-6080(08)00010-X

DOI
10.1016/S0378-6080(08)00010-X
Chapter

Comparison of S-(+)-ketamine- with sufentanil-based anaesthesia for elective coronary artery bypass graft surgery:: effect on troponin T levels

Neuhaeuser, C., Preiss, V., Feurer, M. -K., Mueller, M., Scholz, S., Kwapisz, M., . . . Welters, I. D. (2008). Comparison of S-(+)-ketamine- with sufentanil-based anaesthesia for elective coronary artery bypass graft surgery:: effect on troponin T levels. BRITISH JOURNAL OF ANAESTHESIA, 100(6), 765-771. doi:10.1093/bja/aen095

DOI
10.1093/bja/aen095
Journal article

General anesthetics and therapeutic gases

Welters, I. D., & Leuwer, M. (2008). General anesthetics and therapeutic gases. In SIDE EFFECTS OF DRUGS ANNUAL 30: A WORLDWIDE YEARLY SURVEY OF NEW DATA AND TRENDS IN ADVERSE DRUG REACTIONS AND INTERACTIONS (Vol. 30, pp. 137-151). doi:10.1016/S0378-6080(08)00010-X

DOI
10.1016/S0378-6080(08)00010-X
Chapter

Response of proopiomelanocortin and gonado- or lactotroph systems to in-vitro fertilisation procedures stress

Harbach, H., Antrecht, K., Boedeker, R. -H., Brenck, F., Gips, H., Hempelmann, G., . . . Zygmunt, M. (2008). Response of proopiomelanocortin and gonado- or lactotroph systems to in-vitro fertilisation procedures stress. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 141(2), 137-142. doi:10.1016/j.ejogrb.2008.08.001

DOI
10.1016/j.ejogrb.2008.08.001
Journal article

Response to delivery stress is not mediated by beta-endorphin (1-31)

Harbach, H., Antrecht, K., Boedeker, R. -H., Hempelmann, G., Markart, P., Matejec, R., . . . Zygmunt, M. (2008). Response to delivery stress is not mediated by beta-endorphin (1-31). EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 136(1), 39-45. doi:10.1016/j.ejogrb.2007.02.004

DOI
10.1016/j.ejogrb.2007.02.004
Journal article

2007

Functional significance of ACTH and β-endorphin for the proopiomelanocortin and immune response to stress

Harbach, H., Hempelmann, G., Matejec, R., Langefeld, T. W., Menzebach, A., & Welters, I. D. (2007). Functional significance of ACTH and β-endorphin for the proopiomelanocortin and immune response to stress. Anasthesiologie und Intensivmedizin, 48(11), 592-603.

Journal article

Morphine inhibits AP-1 activity and CD 14 expression in leukocytes by a nitric oxide and opioid receptor-dependent mechanism

Welters, I. D., Menzebach, A., Goumon, Y., Langefeld, T. W., Harbach, H., Muehling, J., . . . Stefano, G. B. (2007). Morphine inhibits AP-1 activity and CD 14 expression in leukocytes by a nitric oxide and opioid receptor-dependent mechanism. EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 24(11), 958-965. doi:10.1017/S026502150700083X

DOI
10.1017/S026502150700083X
Journal article

Pathways involved in alanyl-glutamine-induced changes in neutrophil amino- and α-keto acid homeostasis or immunocompetence

Muehling, J., Burchert, D., Langefeld, T. W., Matejec, R., Harbach, H., Engel, J., . . . Hempelmann, G. (2007). Pathways involved in alanyl-glutamine-induced changes in neutrophil amino- and α-keto acid homeostasis or immunocompetence. AMINO ACIDS, 33(3), 511-524. doi:10.1007/s00726-006-0395-x

DOI
10.1007/s00726-006-0395-x
Journal article

2006

Effect of Isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease

Neuhaeuser, C., Mueller, M., Welters, I., Scholz, S., & Kwapisz, M. M. (2006). Effect of Isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 20(4), 509-514. doi:10.1053/j.jvca.2006.01.018

DOI
10.1053/j.jvca.2006.01.018
Journal article

Nitric oxide and polyamine pathway-dependent modulation of neutrophil free amino- and α-keto acid profiles or host defense capability

Muehling, J., Engel, J., Halabi, M., Mueller, M., Fuchs, M., Kruell, M., . . . Hempelmann, G. (2006). Nitric oxide and polyamine pathway-dependent modulation of neutrophil free amino- and α-keto acid profiles or host defense capability. AMINO ACIDS, 31(1), 11-26. doi:10.1007/s00726-006-0273-6

DOI
10.1007/s00726-006-0273-6
Journal article

Performance and customization of 4 prognostic models for postoperative onset of nausea and vomiting in ear, nose, and throat surgery

Engel, J. M., Junger, A., Hartmann, B., Little, S., Schnoebel, R., Mann, V., . . . Hempelmann, G. (2006). Performance and customization of 4 prognostic models for postoperative onset of nausea and vomiting in ear, nose, and throat surgery. JOURNAL OF CLINICAL ANESTHESIA, 18(4), 256-263. doi:10.1016/j.jclinane.2005.10.003

DOI
10.1016/j.jclinane.2005.10.003
Journal article

Thiopentone reduces neutrophil receptor expression

Welters, I., Hafer, G., Muehling, J., Engel, J., & Hempelmann, G. (2006). Thiopentone reduces neutrophil receptor expression. European Journal of Anaesthesiology, 23(Supplement 37), 150-151. doi:10.1097/00003643-200606001-00540

DOI
10.1097/00003643-200606001-00540
Journal article

Identification of morphine-6-glucuronide in chromaffin cell secretory granules

Goumon, Y., Muller, A., Glattard, E., Marban, C., Gasnier, C., Strub, J. M., . . . Metz-Boutigue, M. H. (2006). Identification of morphine-6-glucuronide in chromaffin cell secretory granules. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(12), 8082-8089. doi:10.1074/jbc.M502298200

DOI
10.1074/jbc.M502298200
Journal article

Comparison of three scoring systems in medical intensive care patients

Welters, I. D., Röhrig, R., Sander, O., Mogk, M., & Sparenborg, H. (2006). Comparison of three scoring systems in medical intensive care patients. Intensive Care Med, 32(Suppl.), S59.

Journal article

2005

Alterations in neutrophil (PMN) free intracellular alpha-keto acid profiles and immune functions induced by L-alanyl-L-glutamine, arginine or taurine

Mühling, J., Nickolaus, K. A., Halabi, M., Fuchs, M., Krüll, M., Engel, J., . . . Hempelmann, G. (2005). Alterations in neutrophil (PMN) free intracellular alpha-keto acid profiles and immune functions induced by L-alanyl-L-glutamine, arginine or taurine. AMINO ACIDS, 29(3), 289-300. doi:10.1007/s00726-005-0223-8

DOI
10.1007/s00726-005-0223-8
Journal article

Activation of Granulocytes and Antiproteases in open heart surgery

Welters, I. D., Hirsch, J., Menzebach, A., Hempelmann, G., & Müller, M. (2005). Activation of Granulocytes and Antiproteases in open heart surgery. ANASTHESIOLOGIE INTENSIVMEDIZIN NOTFALLMEDIZIN SCHMERZTHERAPIE, 40(3), 164-172. doi:10.1055/s-2005-861042

DOI
10.1055/s-2005-861042
Journal article

Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and α-keto acid profiles or immune functions

Mühling, J., Gonter, J., Nickolaus, K. A., Matejec, R., Welters, I. D., Wolff, M., . . . Hempelmann, G. (2005). Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and α-keto acid profiles or immune functions. AMINO ACIDS, 28(1), 85-98. doi:10.1007/s00726-004-0136-y

DOI
10.1007/s00726-004-0136-y
Journal article

Impact of prolonged elevated heart rate on incidence of major cardiac events in critically ill patients with a high risk of cardiac complications

Sander, O., Welters, I. D., Foëk, P., & Sear, J. W. (2005). Impact of prolonged elevated heart rate on incidence of major cardiac events in critically ill patients with a high risk of cardiac complications. CRITICAL CARE MEDICINE, 33(1), 81-88. doi:10.1097/01.CCM.0000150028.64264.14

DOI
10.1097/01.CCM.0000150028.64264.14
Journal article

Morphine inhibits AP-1 nuclear binding in human leukocytes

Welters, I. D., Menzebach, A., Engel, J., Mühling, J., & Hempelmann, G. (2005). Morphine inhibits AP-1 nuclear binding in human leukocytes. Intensive Care Med, 31, S72.

Journal article

2004

Effects of ornithine on neutrophil (PMN) free amino acid and α-keto acid profiles and immune functions <i>in vitro</i>

Mühling, J., Fuchs, M., Campos, M., Gonter, J., Sablotzki, A., Engel, J., . . . Hempelmann, G. (2004). Effects of ornithine on neutrophil (PMN) free amino acid and α-keto acid profiles and immune functions <i>in vitro</i>. AMINO ACIDS, 27(3-4), 313-319. doi:10.1007/s00726-004-0126-0

DOI
10.1007/s00726-004-0126-0
Journal article

ACE inhibitors enalaprilat and quinaprilat inhibit monocyte surface receptor expression

Welters, I. D., Reyher, C., Hafer, G., Hempelmann, G., Menzebach, A., Müller, M., & Heidt, M. C. (2004). ACE inhibitors enalaprilat and quinaprilat inhibit monocyte surface receptor expression. European Journal of Anaesthesiology, 21(Supplement 33), 7. doi:10.1097/00003643-200406001-00017

DOI
10.1097/00003643-200406001-00017
Journal article

Inhaled iloprost in the management of pulmonary hypertension in infants undergoing congenital heart surgery

Mueller, M., Neuhaeuser, C., Noest, R., Akintuerk, H., Welters, I., & Hempelmann, G. (2004). Inhaled iloprost in the management of pulmonary hypertension in infants undergoing congenital heart surgery. European Journal of Anaesthesiology, 21(Supplement 33), 3. doi:10.1097/00003643-200406001-00006

DOI
10.1097/00003643-200406001-00006
Journal article

Morphine inhibits complement receptor expression, phagocytosis and oxidative burst by a nitric oxide dependant mechanism

Menzebach, A., Hirsch, J., Nöst, R., Mogk, M., Hempelmann, G., & Welters, I. D. (2004). Morphine inhibits complement receptor expression, phagocytosis and oxidative burst by a nitric oxide dependant mechanism. ANASTHESIOLOGIE INTENSIVMEDIZIN NOTFALLMEDIZIN SCHMERZTHERAPIE, 39(4), 204-211. doi:10.1055/s-2004-814389

DOI
10.1055/s-2004-814389
Journal article

The hippocampal cholinergic neurostimulating peptide, the N-terminal fragment of the secreted phosphatidylethanolamine-binding protein, possesses a new biological activity on cardiac physiology

Goumon, Y., Angelone, T., Schoentgen, F. O., Chasserot-Golaz, S., Almas, B., Fukami, M. M., . . . Metz-Boutigue, M. H. (2004). The hippocampal cholinergic neurostimulating peptide, the N-terminal fragment of the secreted phosphatidylethanolamine-binding protein, possesses a new biological activity on cardiac physiology. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(13), 13054-13064. doi:10.1074/jbc.M308533200

DOI
10.1074/jbc.M308533200
Journal article

2003

Effects of endogenous and synthetic opioid peptides on neutrophil function <i>in vitro</i>

Menzebach, A., Hirsch, J., Hempelmann, G., & Welters, I. D. (2003). Effects of endogenous and synthetic opioid peptides on neutrophil function <i>in vitro</i>. BRITISH JOURNAL OF ANAESTHESIA, 91(4), 546-550. doi:10.1093/bja/aeg219

DOI
10.1093/bja/aeg219
Journal article

Is immunomodulation by opioid drugs of clinical relevance?

Welters, I. D. (2003). Is immunomodulation by opioid drugs of clinical relevance?. CURRENT OPINION IN ANESTHESIOLOGY, 16(5), 509-513. doi:10.1097/00001503-200310000-00011

DOI
10.1097/00001503-200310000-00011
Journal article

Indicators of erythrocyte damage after microwave warming of packed red blood cells

Hirsch, J., Menzebach, A., Welters, I. D., Dietrich, G. V., Katz, N., & Hempelmann, G. (2003). Indicators of erythrocyte damage after microwave warming of packed red blood cells. CLINICAL CHEMISTRY, 49(5), 792-799. doi:10.1373/49.5.792

DOI
10.1373/49.5.792
Journal article

Opioids and immunosuppression. Clinical relevance?

Welters, I. (2003). Opioids and immunosuppression. Clinical relevance?. ANAESTHESIST, 52(5), 442-452. doi:10.1007/s00101-003-0506-y

DOI
10.1007/s00101-003-0506-y
Journal article

Temperature course and distribution during plasma heating with a microwave device

Hirsch, J., Bach, R., Menzebach, A., Welters, I. D., Dietrich, G. V., & Hempelmann, G. (2003). Temperature course and distribution during plasma heating with a microwave device. ANAESTHESIA, 58(5), 444-447. doi:10.1046/j.1365-2044.2003.03086.x

DOI
10.1046/j.1365-2044.2003.03086.x
Journal article

2001

Inhibitory effects of S-(-) and R-(+) bupivacaine on neutrophil function

Welters, I. D., Menzebach, A., Langefeld, T. W., Menzebach, M., & Hempelmann, G. (2001). Inhibitory effects of S-(-) and R-(+) bupivacaine on neutrophil function. ACTA ANAESTHESIOLOGICA SCANDINAVICA, 45(5), 570-575. doi:10.1034/j.1399-6576.2001.045005570.x

DOI
10.1034/j.1399-6576.2001.045005570.x
Journal article

Influence of colloid fluids on polymorphonuclear granulocyte function <i>in vivo</i>

Engel, J. M., Welters, I., Rupp, M., Langefeld, T., Ruwoldt, R., Menges, T., & Hempelmann, G. (2001). Influence of colloid fluids on polymorphonuclear granulocyte function <i>in vivo</i>. ACTA ANAESTHESIOLOGICA SCANDINAVICA, 45(3), 385-389. doi:10.1034/j.1399-6576.2001.045003385.x

DOI
10.1034/j.1399-6576.2001.045003385.x
Journal article

2000

Processing of proenkephalin-A in bovine chromaffin cells - Identification of natural derived fragments by N-terminal sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry

Goumon, Y., Lugardon, K., Gadroy, P., Strub, J. M., Welters, I. D., Stefano, G. B., . . . Metz-Boutigue, M. H. (2000). Processing of proenkephalin-A in bovine chromaffin cells - Identification of natural derived fragments by N-terminal sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(49), 38355-38362. doi:10.1074/jbc.M007557200

DOI
10.1074/jbc.M007557200
Journal article

Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and μ<sub>3</sub> opiate receptor-dependent mechanism

Welters, I. D., Menzebach, A., Goumon, Y., Langefeld, T. W., Teschemacher, H., Hempelmann, G., & Stefano, G. B. (2000). Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and μ<sub>3</sub> opiate receptor-dependent mechanism. JOURNAL OF NEUROIMMUNOLOGY, 111(1-2), 139-145. doi:10.1016/S0165-5728(00)00401-X

DOI
10.1016/S0165-5728(00)00401-X
Journal article

Endogenous morphine

Stefano, G. B., Goumon, Y., Casares, F., Cadet, P., Fricchione, G. L., Rialas, C., . . . Bianchi, E. (2000). Endogenous morphine. TRENDS IN NEUROSCIENCES, 23(9), 436-442. doi:10.1016/S0166-2236(00)01611-8

DOI
10.1016/S0166-2236(00)01611-8
Journal article

<i>Ascaris suum</i>, an intestinal parasite, produces morphine

Goumon, Y., Casares, F., Pryor, S., Ferguson, L., Brownawell, B., Cadet, P., . . . Stefano, G. B. (2000). <i>Ascaris suum</i>, an intestinal parasite, produces morphine. JOURNAL OF IMMUNOLOGY, 165(1), 339-343. doi:10.4049/jimmunol.165.1.339

DOI
10.4049/jimmunol.165.1.339
Journal article

Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor.

Stefano, G. B., Cadet, P., Breton, C., Goumon, Y., Prevot, V., Dessaint, J. P., . . . Salzet, M. (2000). Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor.. Blood, 95(12), 3951-3958.

Journal article

Morphine inbibits NF-κB nuclear binding in human neutrophils and monocytes by a nitric oxide-dependent mechanism

Welters, I. D., Menzebach, A., Goumon, Y., Cadet, P., Menges, T., Hughes, T. K., . . . Stefano, G. B. (2000). Morphine inbibits NF-κB nuclear binding in human neutrophils and monocytes by a nitric oxide-dependent mechanism. ANESTHESIOLOGY, 92(6), 1677-1684. doi:10.1097/00000542-200006000-00027

DOI
10.1097/00000542-200006000-00027
Journal article

Antagonism of LPS and IFN-γ induced iNOS expression in human atrial endothelia by morphine, anandamide, and estrogen

Fimiani, C., Magazine, H., Welters, I. D., Bilfinger, T. V., Salsano, F., Tonnesen, E., & Stefano, G. B. (2000). Antagonism of LPS and IFN-γ induced iNOS expression in human atrial endothelia by morphine, anandamide, and estrogen. ACTA PHARMACOLOGICA SINICA, 21(5), 405-409. Retrieved from https://www.webofscience.com/

Journal article

Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia

Stefano, G. B., Prevot, V., Beauvillain, J. C., Cadet, P., Fimiani, C., Welters, I., . . . Bilfinger, T. V. (2000). Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia. CIRCULATION, 101(13), 1594-1597. doi:10.1161/01.CIR.101.13.1594

DOI
10.1161/01.CIR.101.13.1594
Journal article

Basal nitric oxide limits immune, nervous and cardiovascular excitation: human endothelia express a mu opiate receptor

Stefano, G. B., Goumon, Y., Bilfinger, T. V., Welters, I. D., & Cadet, P. (2000). Basal nitric oxide limits immune, nervous and cardiovascular excitation: human endothelia express a mu opiate receptor. PROGRESS IN NEUROBIOLOGY, 60(6), 513-530. doi:10.1016/S0301-0082(99)00038-6

DOI
10.1016/S0301-0082(99)00038-6
Journal article

Reduction of Postoperative Nausea and Vomiting by Dimenhydrinate Suppositories after Strabismus Surgery in Children

Welters, I. D., Menges, T., Gräf, M., Beikirch, C., Menzebach, A., & Hempelmann, G. (2000). Reduction of Postoperative Nausea and Vomiting by Dimenhydrinate Suppositories after Strabismus Surgery in Children. Anesthesia &amp; Analgesia, 90(2), 311-314. doi:10.1213/00000539-200002000-00013

DOI
10.1213/00000539-200002000-00013
Journal article

Postoperative nausea and vomiting after Faden operation

Welters, I. D., Graef, M., Menges, T., Beikirch, C., Kaufmann, H., & Hempelmann, G. (2000). Postoperative nausea and vomiting after Faden operation. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 238(1), 59-63. doi:10.1007/s004170050010

DOI
10.1007/s004170050010
Journal article

Influence of kolloids on neutrophil function

Welters, I. D., Spangenberg, U., Menzebach, A., Engel, J., Menges, T., Langefeld, T. W., & Hempelmann, G. (2000). Influence of kolloids on neutrophil function. ANAESTHESIST, 49(3), 196-201. doi:10.1007/s001010050814

DOI
10.1007/s001010050814
Journal article

NF-κB, nitric oxide and opiate signaling

Welters, I. D., Fimiani, C., Bilfinger, T. V., & Stefano, G. B. (2000). NF-κB, nitric oxide and opiate signaling. MEDICAL HYPOTHESES, 54(2), 263-268. doi:10.1054/mehy.1999.0032

DOI
10.1054/mehy.1999.0032
Journal article

Reduction of postoperative nausea and vomiting by dimenhydrinate suppositories after strabismus surgery in children

Welters, I. D., Menges, T., Gräf, M., Beikirch, C., Menzebach, A., & Hempelmann, G. (2000). Reduction of postoperative nausea and vomiting by dimenhydrinate suppositories after strabismus surgery in children. ANESTHESIA AND ANALGESIA, 90(2), 311-314. doi:10.1097/00000539-200002000-00013

DOI
10.1097/00000539-200002000-00013
Journal article

1999

Estradiol coupling to human monocyte nitric oxide release is dependent on intracellular calcium transients: Evidence for an estrogen surface receptor

Stefano, G. B., Prevot, V., Beauvillain, J. C., Fimiani, C., Welters, I., Cadet, P., . . . Bilfinger, T. V. (1999). Estradiol coupling to human monocyte nitric oxide release is dependent on intracellular calcium transients: Evidence for an estrogen surface receptor. JOURNAL OF IMMUNOLOGY, 163(7), 3758-3763. Retrieved from https://www.webofscience.com/

Journal article

Changes in blood lymphocyte populations after multiple trauma: Association with posttraumatic complications

Menges, T., Engel, J., Welters, I., Wagner, R. M., Little, S., Ruwoldt, R., . . . Hempelmann, G. (1999). Changes in blood lymphocyte populations after multiple trauma: Association with posttraumatic complications. CRITICAL CARE MEDICINE, 27(4), 733-740. doi:10.1097/00003246-199904000-00026

DOI
10.1097/00003246-199904000-00026
Journal article

1998

Thrombin generation and activation of the thrombomodulin protein C system in open heart surgery depend on the underlying cardiac disease

Welters, I., Menges, T., Ballesteros, M., Knothe, C., Ruwoldt, R., Görlach, G., & Hempelmann, G. (1998). Thrombin generation and activation of the thrombomodulin protein C system in open heart surgery depend on the underlying cardiac disease. THROMBOSIS RESEARCH, 92(1), 1-9. doi:10.1016/S0049-3848(98)00095-4

DOI
10.1016/S0049-3848(98)00095-4
Journal article

Acute phase and opsonin response in cardiac surgery patients: influence of underlying cardiac disease

Welters, I., Menges, T., Ballesteros, M., Sablotzki, A., Goerlach, G., & Hempelmann, G. (1998). Acute phase and opsonin response in cardiac surgery patients: influence of underlying cardiac disease. PERFUSION-UK, 13(6), 447-454. doi:10.1177/026765919801300608

DOI
10.1177/026765919801300608
Journal article

1997

Development of an algorithm for optimising plasmapheresis filters

Dietrich, G. V., Heinbuch, G., Welters, I., Menges, T., & Hempelmann, G. (1997). Development of an algorithm for optimising plasmapheresis filters. Infusionstherapie und Transfusionsmedizin, 24(4), 307.

Journal article

Effect of intravascular volume load after induction of anaesthesia on oxygen consumption in cardiac surgery patients

Ballesteros, M., Welters, I., Boldt, J., Zickmann, B., Knothe, C., & Hempelmann, G. (1997). Effect of intravascular volume load after induction of anaesthesia on oxygen consumption in cardiac surgery patients. In British Journal of Anaesthesia Vol. 79 (pp. 10).

Conference Paper

Plasma levels of immunoinhibitory cytokines interleukin-10 and transforming growth factor-beta in patients undergoing coronary artery bypass grafting

Sablotzki, A., Welters, I., Lehmann, N., Menges, T., Gorlach, G., Dehne, M., & Hempelmann, G. (1997). Plasma levels of immunoinhibitory cytokines interleukin-10 and transforming growth factor-beta in patients undergoing coronary artery bypass grafting. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 11(4), 763-768. doi:10.1016/S1010-7940(97)01154-8

DOI
10.1016/S1010-7940(97)01154-8
Journal article

ASSOCIATION OF A BI-ALLELIC NCOI POLYMORPHISM WITHIN THE TNF LOCUS WITH THE PROGNOSIS AND OUTCOME OF SEVERELY INJURED TRAUMA PATIENTS

Menges, T., Gronau, S., Kostrezewa, M., Welters, I., Little, S. G., Wagner, R. M., . . . Hempelmann, G. (1997). ASSOCIATION OF A BI-ALLELIC NCOI POLYMORPHISM WITHIN THE TNF LOCUS WITH THE PROGNOSIS AND OUTCOME OF SEVERELY INJURED TRAUMA PATIENTS. Shock, 7(Supplement), 17. doi:10.1097/00024382-199703001-00070

DOI
10.1097/00024382-199703001-00070
Journal article

The influence of acute preoperative plasmapheresis on coagulation tests, fibrinolysis, blood loss and transfusion requirements in cardiac surgery (Retracted article. See vol. 55, pg. 1024, 2019)

Menges, T., Welters, I., Wagner, R. M., Boldt, J., Dapper, F., & Hempelmann, G. (1997). The influence of acute preoperative plasmapheresis on coagulation tests, fibrinolysis, blood loss and transfusion requirements in cardiac surgery (Retracted article. See vol. 55, pg. 1024, 2019). EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 11(3), 557-563. doi:10.1016/S1010-7940(96)01093-7

DOI
10.1016/S1010-7940(96)01093-7
Journal article

Alterations of the cytokine network in patients undergoing cardiopulmonary bypass

Sablotzki, A., Dehne, M., Welters, I., Menges, T., Lehmann, N., Goerlach, G., . . . Hempelmann, G. (1997). Alterations of the cytokine network in patients undergoing cardiopulmonary bypass. PERFUSION-UK, 12(6), 393-403. doi:10.1177/026765919701200608

DOI
10.1177/026765919701200608
Journal article

Can albumin reduce platelet damage during extracorporeal circulation?

Welters, I., Menges, T., Zickmann, B., Knothe, C., & Hempelmann, G. (1997). Can albumin reduce platelet damage during extracorporeal circulation?. In British Journal of Anaesthesia Vol. 79 (pp. 36).

Conference Paper

Concentration of cefamandole in plasma and tissues of patients undergoing cardiac surgery: The influence of different cefamandole dosage

Menges, T., Sablotzki, A., Welters, I., Wagner, R. M., Zickmann, B., Gronau, S., . . . Hempelmann, G. (1997). Concentration of cefamandole in plasma and tissues of patients undergoing cardiac surgery: The influence of different cefamandole dosage. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 11(5), 565-570. doi:10.1016/S1053-0770(97)90005-7

DOI
10.1016/S1053-0770(97)90005-7
Journal article

Thrombin generation and protein C activation in cardiac surgery patients

Welters, I., Menges, T., Knothe, C., Ballesteros, M., & Hempelmann, G. (1997). Thrombin generation and protein C activation in cardiac surgery patients. In British Journal of Anaesthesia Vol. 79 (pp. 11).

Conference Paper

1996

Free Papers

Emmanuel, G., Carranza, S., Vettichira, S., Paradis, M., Lie, T., Kessler, P., . . . Vanderkelen, A. (1996). Free Papers. Intensive Care Medicine, 22(S3), S339-S344. doi:10.1007/bf03216428

DOI
10.1007/bf03216428
Journal article

Changes of neopterin, soluble interleukin-2 receptor, interleukin-2 and interleukin-6 in patients undergoing coronary artery bypass grafting

Sablotzki, A., Welters, I., Menges, T., Lehmann, N., Gorlach, G., Hehrlein, F. W., & Hempelmann, G. (1996). Changes of neopterin, soluble interleukin-2 receptor, interleukin-2 and interleukin-6 in patients undergoing coronary artery bypass grafting. Cor Europaeum - European Journal of Cardiac Interventions, 5(3), 106-109.

Journal article

Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients

Boldt, J., Muller, M., Heyn, S., Welters, I., & Hempelmann, G. (1996). Influence of long-term continuous intravenous administration of pentoxifylline on endothelial-related coagulation in critically ill patients. CRITICAL CARE MEDICINE, 24(6), 940-946. doi:10.1097/00003246-199606000-00011

DOI
10.1097/00003246-199606000-00011
Journal article

Normothermic versus hypothermic cardiopulmonary bypass: Do changes in coagulation differ? (Retracted article. See vol. 111, 2021)

Boldt, J., Knothe, C., Welters, I., Dapper, F. L., & Hempelmann, G. (1996). Normothermic versus hypothermic cardiopulmonary bypass: Do changes in coagulation differ? (Retracted article. See vol. 111, 2021). ANNALS OF THORACIC SURGERY, 62(1), 130-135. doi:10.1016/0003-4975(96)00239-1

DOI
10.1016/0003-4975(96)00239-1
Journal article

The role the protein C-thrombomodulin system and fibrinolysis during cardiovascular surgery: Influence of acute preoperative plasmapheresis

Menges, T., Wagner, R. M., Welters, I., Ruwoldt, R., Boldt, J., & Hempelmann, G. (1996). The role the protein C-thrombomodulin system and fibrinolysis during cardiovascular surgery: Influence of acute preoperative plasmapheresis. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 10(4), 482-489. doi:10.1016/S1053-0770(05)80009-6

DOI
10.1016/S1053-0770(05)80009-6
Journal article

1995

[Effect of controlled hypotension using sodium nitroprusside on platelet aggregation].

Heesen, M., Dietrich, G. V., Wirth, R., Ballesteros, M., Welters, I., & Hempelmann, G. (1995). [Effect of controlled hypotension using sodium nitroprusside on platelet aggregation].. Revista espanola de anestesiologia y reanimacion, 42(8), 320-323.

Journal article

DOES THE TYPE OF VOLUME THERAPY INFLUENCE ENDOTHELIAL-RELATED COAGULATION IN THE CRITICALLY ILL (Retracted article. See vol. 125, pg. 415, 2020)

BOLDT, J., HEESEN, M., WELTERS, I., PADBERG, W., MARTIN, K., & HEMPELMANN, G. (1995). DOES THE TYPE OF VOLUME THERAPY INFLUENCE ENDOTHELIAL-RELATED COAGULATION IN THE CRITICALLY ILL (Retracted article. See vol. 125, pg. 415, 2020). BRITISH JOURNAL OF ANAESTHESIA, 75(6), 740-746. doi:10.1093/bja/75.6.740

DOI
10.1093/bja/75.6.740
Journal article

ENDOTHELIAL-RELATED COAGULATION IN CARDIAC-SURGERY (Retracted article. See vol. 125, pg. 415, 2020)

BOLDT, J., SCHINDLER, E., KNOTHE, C., WELTERS, I., STERTMANN, W. A., & HEMPELMANN, G. (1995). ENDOTHELIAL-RELATED COAGULATION IN CARDIAC-SURGERY (Retracted article. See vol. 125, pg. 415, 2020). BRITISH JOURNAL OF ANAESTHESIA, 74(2), 174-179. doi:10.1093/bja/74.2.174

DOI
10.1093/bja/74.2.174
Journal article

THE EFFECT OF THE ANTICOAGULATION REGIMEN ON ENDOTHELIAL-RELATED COAGULATION IN CARDIAC-SURGERY PATIENTS (Retracted article. See vol. 70, pg. 1104, 2015)

BOLDT, J., SCHINDLER, E., WELTERS, I., WITTSTOCK, M., STERTMANN, W. A., & HEMPELMANN, G. (1995). THE EFFECT OF THE ANTICOAGULATION REGIMEN ON ENDOTHELIAL-RELATED COAGULATION IN CARDIAC-SURGERY PATIENTS (Retracted article. See vol. 70, pg. 1104, 2015). ANAESTHESIA, 50(11), 954-960. doi:10.1111/j.1365-2044.1995.tb05927.x

DOI
10.1111/j.1365-2044.1995.tb05927.x
Journal article

1994

Intracranial bleeding and hemostasis. Improved management of patients with intracranial bleeding by measurements of activation products of coagulation and its control

Menges, T., Lessen, V. A., Welters, I., Wagner, R. M., Ruwoldt, R., Boldt, J., & Hempelmann, G. (1994). Intracranial bleeding and hemostasis. Improved management of patients with intracranial bleeding by measurements of activation products of coagulation and its control. Infusionstherapie und Transfusionsmedizin, 21(4), 244-250.

Journal article

INTRACRANIAL BLEEDING AND HEMOSTASIS - IMPROVED MANAGEMENT OF PATIENTS WITH INTRACRANIAL BLEEDING BY MEASUREMENTS OF ACTIVATION PRODUCTS OF COAGULATION AND ITS CONTROL

MENGES, T., VONLESSEN, A., WELTERS, I., WAGNER, R. M., RUWOLDT, R., BOLDT, J., & HEMPELMANN, G. (1994). INTRACRANIAL BLEEDING AND HEMOSTASIS - IMPROVED MANAGEMENT OF PATIENTS WITH INTRACRANIAL BLEEDING BY MEASUREMENTS OF ACTIVATION PRODUCTS OF COAGULATION AND ITS CONTROL. INFUSIONSTHERAPIE UND TRANSFUSIONSMEDIZIN, 21(4), 244-250. Retrieved from https://www.webofscience.com/

Journal article

1993

THE INFLUENCE OF DIFFERENT METHODS OF AUTOLOGOUS BLOOD-TRANSFUSION ON PLASMA-LEVELS OF ANTIBIOTICS - STUDY OF THE CEPHALOSPORINE CEFAMANDOLE

MENGES, T., BOLDT, J., SCHOLZ, K., WAGNER, R. M., RUWOLDT, R., WELTERS, I., & HEMPELMANN, G. (1993). THE INFLUENCE OF DIFFERENT METHODS OF AUTOLOGOUS BLOOD-TRANSFUSION ON PLASMA-LEVELS OF ANTIBIOTICS - STUDY OF THE CEPHALOSPORINE CEFAMANDOLE. ANAESTHESIST, 42(8), 509-515. Retrieved from https://www.webofscience.com/

Journal article