Stereoselective Aldol reactions - Li enolates Z and E Propionaldehyde enolate and acetaldehyde. Play the animation. Zoom in and take a closer look
Play the animation to observe the aldol reactions. The transition states resemble a chair conformation in which the aldehyde R3 group shown in blue is equatorial. Using the frame next button, manipulate the model to see the various stages. Can you arrange the model to mimic the orientation of the transition states depicted below?
Can you convince yourself that the stereochemistry of the product is as shown?
Control the animation