Publications
Selected publications
- Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina (Journal article - 2018)
- Incidence and progression of diabetic retinopathy in Sub-Saharan Africa: A five year cohort study (Journal article - 2017)
- Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine (Journal article - 2017)
- Individualised variable-interval risk-based screening in diabetic retinopathy: the ISDR research programme including RCT (Journal article - 2023)
- How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria? (Journal article - 2022)
- Incidence of sight-threatening diabetic retinopathy in an established urban screening programme: An 11-year cohort study (Journal article - 2021)
- Localised release of matrix metallopeptidase 8 in fatal cerebral malaria (Journal article - 2021)
- Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT (Journal article - 2021)
- Long-term Visual Outcomes after Release from Protocol in Patients who Participated in the Inhibition of VEGF in Age-related Choroidal Neovascularisation (IVAN) Trial (Conference Paper - 2020)
- Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial (Journal article - 2014)
2024
Effect of Fenofibrate on Progression of Diabetic Retinopathy.
Preiss, D., Logue, J., Sammons, E., Zayed, M., Emberson, J., Wade, R., . . . Armitage, J. (2024). Effect of Fenofibrate on Progression of Diabetic Retinopathy.. NEJM evidence, 3(8), EVIDoa2400179. doi:10.1056/evidoa2400179
The future of academic integrity in the age of artificial intelligence.
Wong, D., Harding, S., & Johnson, M. (2024). The future of academic integrity in the age of artificial intelligence.. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 262(5), 1375-1376. doi:10.1007/s00417-024-06385-1
Convolutional neural network-based classification of glaucoma using optic radiation tissue properties.
Kruper, J., Richie-Halford, A., Benson, N. C., Caffarra, S., Owen, J., Wu, Y., . . . UK Biobank Eye and Vision Consortium. (2024). Convolutional neural network-based classification of glaucoma using optic radiation tissue properties.. Communications medicine, 4(1), 72. doi:10.1038/s43856-024-00496-w
Design, recruitment and baseline characteristics of the LENS trial.
LENS Collaborative Group. (2024). Design, recruitment and baseline characteristics of the LENS trial.. Diabetic medicine : a journal of the British Diabetic Association, e15310. doi:10.1111/dme.15310
2023
A foundation model for generalizable disease detection from retinal images.
Zhou, Y., Chia, M. A., Wagner, S. K., Ayhan, M. S., Williamson, D. J., Struyven, R. R., . . . Keane, P. A. (2023). A foundation model for generalizable disease detection from retinal images.. Nature, 622(7981), 156-163. doi:10.1038/s41586-023-06555-x
Individualised variable-interval risk-based screening in diabetic retinopathy: the ISDR research programme including RCT
Harding, S., Alshukri, A., Appelbe, D., Broadbent, D., Burgess, P., Byrne, P., . . . Williamson, P. (2023). Individualised variable-interval risk-based screening in diabetic retinopathy: the ISDR research programme including RCT.
Predicting Acute and Post-Recovery Outcomes in Cerebral Malaria and Other Comas by Optical Coherence Tomography (OCT in CM) – A protocol for an observational cohort study of Malawian children
Wilson, K., Tu, Z., Mbale, E., Mhango, P., Kayange, P., Gladstone, M., . . . Beare, N. A. V. (2023). Predicting Acute and Post-Recovery Outcomes in Cerebral Malaria and Other Comas by Optical Coherence Tomography (OCT in CM) – A protocol for an observational cohort study of Malawian children. Wellcome Open Research. doi:10.12688/wellcomeopenres.19166.1
Serum glial fibrillary acidic protein and neurofilament light chain as biomarkers of retinal neurodysfunction in early diabetic retinopathy: results of the EUROCONDOR study
Hernandez, C., Simo-Servat, O., Porta, M., Grauslund, J. P., Harding, S., Frydkjaer-Olsen, U., . . . Simo, R. (2023). Serum glial fibrillary acidic protein and neurofilament light chain as biomarkers of retinal neurodysfunction in early diabetic retinopathy: results of the EUROCONDOR study. ACTA DIABETOLOGICA, 60(6), 837-844. doi:10.1007/s00592-023-02076-1
2022
Long-term Retinal Morphology and Functional Associations in Treated Neovascular Age-Related Macular Degeneration
Peto, T., Evans, R. N., Reeves, B. C., Harding, S., Madhusudhan, S., Lotery, A., . . . Chakravarthy, U. (2022). Long-term Retinal Morphology and Functional Associations in Treated Neovascular Age-Related Macular Degeneration. OPHTHALMOLOGY RETINA, 6(8), 664-675. doi:10.1016/j.oret.2022.03.010
How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?
MacCormick, I. J. C., Barrera, V., Beare, N. A. V., Czanner, G., Potchen, M., Kampondeni, S., . . . Harding, S. P. (2022). How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?. JOURNAL OF INFECTIOUS DISEASES, 225(6), 1070-1080. doi:10.1093/infdis/jiaa541
Visual risk factors for falls in older adults: a case-control study
Mehta, J., Czanner, G., Harding, S., Newsham, D., & Robinson, J. (2022). Visual risk factors for falls in older adults: a case-control study. BMC GERIATRICS, 22(1). doi:10.1186/s12877-022-02784-3
Early Worsening of Retinopathy in People with Diabetes after Rapid Improvement in Glycaemic Control: A Systematic Review
Akil, H., Burgess, J. B., Nevitt, S. N., Harding, S. H., Alam, U. A., & Burgess, P. B. (2021). Early Worsening of Retinopathy in People with Diabetes after Rapid Improvement in Glycaemic Control: A Systematic Review. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 31 (pp. 10). Retrieved from https://www.webofscience.com/
Early Worsening of Retinopathy in Type 1 and Type 2 Diabetes After Rapid Improvement in Glycaemic Control: A Systematic Review
Akil, H., Burgess, J., Nevitt, S., Harding, S. P., Alam, U., & Burgess, P. (2022). Early Worsening of Retinopathy in Type 1 and Type 2 Diabetes After Rapid Improvement in Glycaemic Control: A Systematic Review. DIABETES THERAPY, 13(1), 1-23. doi:10.1007/s13300-021-01190-z
Measuring the Impact of Malaria on the Living Human Retina.
MacCormick, I. J. C., Lewallen, S., Beare, N., & Harding, S. P. (2022). Measuring the Impact of Malaria on the Living Human Retina.. In Unknown Book (Vol. 2470, pp. 731-748). doi:10.1007/978-1-0716-2189-9_54
2021
Incidence of sight-threatening diabetic retinopathy in an established urban screening programme: An 11-year cohort study
Cheyne, C. P., Burgess, P. I., Broadbent, D. M., Garcia-Finana, M., Stratton, I. M., Criddle, T., . . . Harding, S. P. (2021). Incidence of sight-threatening diabetic retinopathy in an established urban screening programme: An 11-year cohort study. DIABETIC MEDICINE, 38(9). doi:10.1111/dme.14583
Visual Risk Factors for Falls in Older Adults: A Case-Control Study
Cerebral malaria: insight into pathology from optical coherence tomography
Tu, Z., Gormley, J., Sheth, V., Seydel, K. B., Taylor, T., Beare, N., . . . Gottlob, I. (2021). Cerebral malaria: insight into pathology from optical coherence tomography. Scientific Reports, 11(1). doi:10.1038/s41598-021-94495-9
Cerebral Malaria: Insight into Pathology from Optical Coherence Tomography
Tu, Z., Gormley, J., Sheth, V., Seydel, K., Taylor, T., Beare, N., . . . Gottlob, I. (2021). Cerebral Malaria: Insight into Pathology from Optical Coherence Tomography. doi:10.21203/rs.3.rs-117786/v2
Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT
Hykin, P., Prevost, A. T., Sivaprasad, S., Vasconcelos, J. C., Murphy, C., Kelly, J., . . . Brazier, J. (2021). Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT. HEALTH TECHNOLOGY ASSESSMENT, 25(38), 1-+. doi:10.3310/hta25380
Metformin, A Potential Role in Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
Romdhoniyyah, D. F., Harding, S. P., Cheyne, C. P., & Beare, N. A. V. (2021). Metformin, A Potential Role in Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis. OPHTHALMOLOGY AND THERAPY, 10(2), 245-260. doi:10.1007/s40123-021-00344-3
Localised release of matrix metallopeptidase 8 in fatal cerebral malaria
Georgiadou, A., Naidu, P., Walsh, S., Kamiza, S., Barrera, V., Harding, S. P., . . . Cunnington, A. J. (2021). Localised release of matrix metallopeptidase 8 in fatal cerebral malaria. CLINICAL & TRANSLATIONAL IMMUNOLOGY, 10(4). doi:10.1002/cti2.1263
End-to-End Deep Learning Vector Autoregressive Prognostic Models to Predict Disease Progression with Uneven Time Intervals
Bridge, J., Harding, S., & Zheng, Y. (2021). End-to-End Deep Learning Vector Autoregressive Prognostic Models to Predict Disease Progression with Uneven Time Intervals. In Unknown Conference (pp. 517-531). Springer International Publishing. doi:10.1007/978-3-030-80432-9_38
Five-Year Incidence and Progression of Age-Related Macular Degeneration in People with Diabetes
Romdhoniyyah, D., Cheyne, C. P., Alshukri, A., Parry, D. G., Finana, M. G., Harding, S. P., & Beare, N. A. V. (2021). Five-Year Incidence and Progression of Age-Related Macular Degeneration in People with Diabetes. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 31 (pp. 4). Retrieved from https://www.webofscience.com/
Macular Function and Structure in Early Diabetic Retinopathy
Ku, J. Y., Harding, S. P., Czanner, G., Zhu, W., & Knox, P. C. (2021). Macular Function and Structure in Early Diabetic Retinopathy. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 31 (pp. 9-10). Retrieved from https://www.webofscience.com/
Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT
Broadbent, D., Wang, A., Cheyne, C., James, M., Lathe, J., Stratton, I., . . . Harding, S. (2021). Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT. Diabetologia, 64(1), 56-69. doi:10.1007/s00125-020-05313-2
2020
Cerebral Malaria: Insight into Pathology from Optical Coherence Tomography
Development and validation of a novel prognostic model for predicting AMD progression using longitudinal fundus images
Bridge, J., Harding, S., & Zheng, Y. (2020). Development and validation of a novel prognostic model for predicting AMD progression using longitudinal fundus images. BMJ Open Ophthalmology, 5(1), e000569. doi:10.1136/bmjophth-2020-000569
Long-term Visual Outcomes after Release from Protocol in Patients who Participated in the Inhibition of VEGF in Age-related Choroidal Neovascularisation (IVAN) Trial
Evans, R. N., Reeves, B. C., Phillips, D., Muldrew, K. A., Rogers, C., Harding, S. P., & Chakravarthy, U. (2020). Long-term Visual Outcomes after Release from Protocol in Patients who Participated in the Inhibition of VEGF in Age-related Choroidal Neovascularisation (IVAN) Trial. In OPHTHALMOLOGY Vol. 127 (pp. 1191-1200). doi:10.1016/j.ophtha.2020.03.020
Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation
Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation
Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation
Byrne, P., Thetford, C., Gabbay, M., Clarke, P., Doncaster, E., Harding, S. P., & Grp, I. S. D. R. S. (2020). Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation. BMC PUBLIC HEALTH, 20(1). doi:10.1186/s12889-020-08974-1
The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial
Hernandez, C., Porta, M., Bandello, F., Grauslund, J., Harding, S. P., Aldington, S. J., . . . Simo, R. (2020). The Usefulness of Serum Biomarkers in the Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial. JOURNAL OF CLINICAL MEDICINE, 9(4). doi:10.3390/jcm9041233
Evolving Longitudinal Retinal Observations in a Cohort of Survivors of Ebola Virus Disease
Steptoe, P. J., Momorie, F., Fornah, A. D., Komba, P., Emsley, E., Scott, J. T., . . . Semple, M. G. (n.d.). Evolving Longitudinal Retinal Observations in a Cohort of Survivors of Ebola Virus Disease. JAMA Ophthalmology. doi:10.1001/jamaophthalmol.2020.0173
Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation
Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation
Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial
Lotery, A., Sivaprasad, S., O'Connell, A., Harris, R. A., Culliford, L., Ellis, L., . . . Reeves, B. C. (2020). Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial. LANCET, 395(10220), 294-303. Retrieved from https://www.webofscience.com/
DAISY Descriptors Combined with Deep Learning to Diagnose Retinal Disease from High Resolution 2D OCT Images
Bridge, J., Harding, S. P., & Zheng, Y. (2020). DAISY Descriptors Combined with Deep Learning to Diagnose Retinal Disease from High Resolution 2D OCT Images. In Unknown Conference (pp. 489-496). Springer International Publishing. doi:10.1007/978-3-030-39343-4_42
AI-Based Method for Detecting Retinal Haemorrhage in Eyes with Malarial Retinopathy
Chen, X., Leak, M., Harding, S. P., & Zheng, Y. (2020). AI-Based Method for Detecting Retinal Haemorrhage in Eyes with Malarial Retinopathy. In Unknown Conference (pp. 439-449). Springer International Publishing. doi:10.1007/978-3-030-39343-4_37
Artificial Intelligence (AI)-based Low-cost System for Automated Screening of Malarial Retinopathy
Joshi, V. S., Kurup, A., Nemeth, S. C., Zamora, G., Soliz, P., Lewallen, S., . . . Taylor, T. (2020). Artificial Intelligence (AI)-based Low-cost System for Automated Screening of Malarial Retinopathy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 61. Retrieved from https://www.webofscience.com/
Safety, Efficacy and Cost Effectiveness of Individualised Screening for Diabetic Retinopathy: The Individualised Screening for Diabetic Retinopathy (ISDR) Single Centre, Open Label, Equivalence Randomised Controlled Trial
Broadbent, D. M., Harding, S. P., Garcia-Finana, M., James, M., Stratton, I. M., Vora, J. P., & Gabbay, M. (2020). Safety, Efficacy and Cost Effectiveness of Individualised Screening for Diabetic Retinopathy: The Individualised Screening for Diabetic Retinopathy (ISDR) Single Centre, Open Label, Equivalence Randomised Controlled Trial. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 30 (pp. 6-7). Retrieved from https://www.webofscience.com/
Spatial Modelling of Retinal Thickness in Images from Patients with Diabetic Macular Oedema
Zhu, W., Ku, J. Y., Zheng, Y., Knox, P., Harding, S. P., Kolamunnage-Dona, R., & Czanner, G. (2020). Spatial Modelling of Retinal Thickness in Images from Patients with Diabetic Macular Oedema. In MEDICAL IMAGE UNDERSTANDING AND ANALYSIS, MIUA 2019 Vol. 1065 (pp. 114-126). doi:10.1007/978-3-030-39343-4_10
Spatial and spatio-temporal statistical analyses of retinal images: a review of methods and applications
Zhu, W., Kolamunnage-Dona, R., Zheng, Y., Harding, S., & Czanner, G. (2020). Spatial and spatio-temporal statistical analyses of retinal images: a review of methods and applications. BMJ OPEN OPHTHALMOLOGY, 5(1). doi:10.1136/bmjophth-2020-000479
2019
Neutrophil extracellular traps drive inflammatory pathogenesis in malaria
Knackstedt, S. L., Georgiadou, A., Apel, F., Abu-Abed, U., Moxon, C. A., Cunnington, A. J., . . . Amulic, B. (2019). Neutrophil extracellular traps drive inflammatory pathogenesis in malaria. SCIENCE IMMUNOLOGY, 4(40). doi:10.1126/sciimmunol.aaw0336
Dictionary Learning Informed Deep Neural Network with Application to OCT Images
Bridge, J., Harding, S. P., Zhao, Y., & Zheng, Y. (2019). Dictionary Learning Informed Deep Neural Network with Application to OCT Images. In Unknown Conference (pp. 1-8). Springer International Publishing. doi:10.1007/978-3-030-32956-3_1
Relationships between handheld Radial Shape Discrimination (hRSD) and Contour Integration Macular Perimetry (CIMP) testing
Alrumizan, M., Harding, S. P., & Knox, P. (2019). Relationships between handheld Radial Shape Discrimination (hRSD) and Contour Integration Macular Perimetry (CIMP) testing. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening
Broadbent, D. M., Sampson, C. J., Wang, A., Howard, L., Williams, A. E., Howlin, S. U., . . . Harding, S. P. (2019). Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening. BMJ OPEN, 9(6). doi:10.1136/bmjopen-2018-025788
Individualised Screening for Diabetic Retinopathy: The ISDR Study-A Randomised Controlled Trial of Safety, Efficacy, and Cost-Effectiveness
Broadbent, D. M., Wang, A., Cheyne, C. P., Lathe, J. G., Stratton, I. M., Vora, J., . . . Harding, S. P. (2019). Individualised Screening for Diabetic Retinopathy: The ISDR Study-A Randomised Controlled Trial of Safety, Efficacy, and Cost-Effectiveness. In DIABETES Vol. 68. doi:10.2337/db19-39-LB
Safety, Efficacy and Cost Effectiveness of Individualised Screening for Diabetic Retinopathy: The ISDR Randomised Controlled Trial
Broadbent, D., Wang, A., Cheyne, C. P., James, M., Lathe, J. G., Stratton, I. M., . . . Harding, S. P. (2019). Safety, Efficacy and Cost Effectiveness of Individualised Screening for Diabetic Retinopathy: The ISDR Randomised Controlled Trial.
Ophthalmology research in the UK's National Health Service: the structure and performance of the NIHR's Ophthalmology research portfolio
Dawson, S. R., Linton, E., Beicher, K., Gale, R., Patel, P., Ghanchi, F., . . . Barry, R. (2019). Ophthalmology research in the UK's National Health Service: the structure and performance of the NIHR's Ophthalmology research portfolio. EYE, 33(4), 610-618. doi:10.1038/s41433-018-0251-8
Personalized risk‐based screening for diabetic retinopathy: A multivariate approach versus the use of stratification rules
Garcia-Finana, M., Hughes, D., Cheyne, C. P., Broadbent, D. M., wang., Wang, A., . . . Harding, S. (2019). Personalized risk‐based screening for diabetic retinopathy: A multivariate approach versus the use of stratification rules. Diabetes, Obesity and Metabolism, 21(3), 560-568. doi:10.1111/dom.13552
Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial
Simo, R., Hernandez, C., Porta, M., Bandello, F., Grauslund, J., Harding, S. P., . . . Riera, L. (2019). Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial. DIABETES, 68(2), 457-463. doi:10.2337/db18-0682
Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα
Sharif, U., Mahmud, N. M., Kay, P., Yang, Y. C., Harding, S., Grierson, I., . . . Paraoan, L. (2019). Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα. Journal of Cellular and Molecular Medicine, 23(1), 405-416. doi:10.1111/jcmm.13944
Clinical implementation of malarial retinopathy screening system for improved diagnosis of cerebral malaria
Joshi, V. S., Wigdahl, J. C., Nemeth, S. C., Zamora, G., Soliz, P., Lewallen, S., . . . Taylor, T. (2019). Clinical implementation of malarial retinopathy screening system for improved diagnosis of cerebral malaria. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
Deep learning for diabetic retinopathy diagnosis & analysis
Pratt, H. (2019). Deep learning for diabetic retinopathy diagnosis & analysis.
Feature visualisation of classification of diabetic retinopathy using a convolutional neural network
Pratt, H., Coenen, F., Harding, S. P., Broadbent, D. M., & Zheng, Y. (2019). Feature visualisation of classification of diabetic retinopathy using a convolutional neural network. In CEUR Workshop Proceedings Vol. 2429 (pp. 23-29).
Intralesional Macular Atrophy in Anti–Vascular Endothelial Growth Factor Therapy for Age-Related Macular Degeneration in the IVAN Trial
Bailey, C., Scott, L. J., Rogers, C. A., Reeves, B. C., Hamill, B., Peto, T., . . . IVAN Study Group. (2019). Intralesional Macular Atrophy in Anti–Vascular Endothelial Growth Factor Therapy for Age-Related Macular Degeneration in the IVAN Trial. OPHTHALMOLOGY, 126(1), 75-86. doi:10.1016/j.ophtha.2018.07.013
LEARNING THE FEATURES OF DIABETIC RETINOPATHY WITH CONVOLUTIONAL NEURAL NETWORKS
Pratt, H., Williams, B. M., Broadbent, D., Harding, S. P., Coenen, F., & Zheng, Y. (2019). LEARNING THE FEATURES OF DIABETIC RETINOPATHY WITH CONVOLUTIONAL NEURAL NETWORKS. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 29 (pp. NP15-NP16). Retrieved from https://www.webofscience.com/
Long-term clinical management of neovascular AMD and visual acuity outcome in IVAN trial participants
Reeves, B., Evans, R., Harding, S. P., Lotery, A., & Chakravarthy, U. (2019). Long-term clinical management of neovascular AMD and visual acuity outcome in IVAN trial participants. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
Longitudinal Changes of Malarial Retinopathy on Hand-held Optical Coherence Tomography
Tu, Z., Gormley, J., Sheth, V., Seydel, K., Taylor, T., Manda, C., . . . Gottlob, I. (2019). Longitudinal Changes of Malarial Retinopathy on Hand-held Optical Coherence Tomography. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
Retinal morphology and risk factors for the development of macular atrophy during extended follow up in the IVAN trial
Chakravarthy, U., Peto, T., Evans, R., Harding, S. P., & Reeves, B. (2019). Retinal morphology and risk factors for the development of macular atrophy during extended follow up in the IVAN trial. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
The costs of screening for sight-threatening diabetic retinopathy
Harding, S. P., Sampson, C. J., Criddle, T. M., Broadbent, D. M., & James, M. (2019). The costs of screening for sight-threatening diabetic retinopathy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from https://www.webofscience.com/
2018
Radial shape discrimination testing for new-onset neovascular age-related macular degeneration in at-risk eyes
Vazquez, N. P., Harding, S. P., Heimann, H., Czanner, G., & Knox, P. C. (2018). Radial shape discrimination testing for new-onset neovascular age-related macular degeneration in at-risk eyes. PLOS ONE, 13(11). doi:10.1371/journal.pone.0207342
Intralesional macular atrophy in antiVEGF therapy for age-related macular degeneration in the IVAN trial
Harding, S. P., Bailey, C., Scott, L., Rogers, C., Reeves, B., Hamill, B., . . . Chakravarthy, U. (2018). Intralesional macular atrophy in antiVEGF therapy for age-related macular degeneration in the IVAN trial. Ophthalmology, 126(1), 75-86. doi:10.1016/j.ophtha.2018.07.013
High mortality in subjects with both diabetes and HIV in sub-Saharan Africa
Burgess, P. I., Harding, S. P., Kayange, P. C., van Oosterhout, J., Garcia-Finana, M., Msukwa, G., & Allain, T. J. (2018). High mortality in subjects with both diabetes and HIV in sub-Saharan Africa. AIDS, 32(14), 2083-2084. doi:10.1097/QAD.0000000000001929
Automated Detection of Malarial Retinopathy in Retinal Fundus Images obtained in Clinical Settings.
Joshi, V., Wigdahl, J., Nemeth, S., Manda, C., Lewallen, S., Taylor, T., . . . Soliz, P. (2018). Automated Detection of Malarial Retinopathy in Retinal Fundus Images obtained in Clinical Settings.. In Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Vol. 2018 (pp. 5950-5953). doi:10.1109/embc.2018.8513603
Multimodal Imaging and Spatial Analysis of Ebola Retinal Lesions in 14 Survivors of Ebola Virus Disease
Steptoe, P. J., Momorie, F., Fornah, A. D., Komba, S. P., Emsley, E., Scott, J. T., . . . Semple, M. G. (2018). Multimodal Imaging and Spatial Analysis of Ebola Retinal Lesions in 14 Survivors of Ebola Virus Disease. JAMA Ophthalmology, 136(6), 689-693. doi:10.1001/jamaophthalmol.2018.1248
Automated Diagnosis of Fundus Camera Images for Diabetic Retinopathy for Treatment Referral
Coenen, F. P., Pratt, H., Zheng, Y., Harding, S., Williams, B., & Broadbent, D. (2018). Automated Diagnosis of Fundus Camera Images for Diabetic Retinopathy for Treatment Referral. European Journal of Ophthalmology.
Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina
Barrera, V., MacCormick, I. J. C., Czanner, G., Hiscott, P. S., White, V. A., Craig, A. G., . . . Harding, S. P. (2018). Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina. eLife, 7. doi:10.7554/eLife.32208
Incremental cost-effectiveness of screening and laser treatment for diabetic retinopathy and macular edema in Malawi
Vetrini, D., Kiire, C. A., Burgess, P. I., Harding, S. P., Kayange, P. C., Kalua, K., . . . Madan, J. (2018). Incremental cost-effectiveness of screening and laser treatment for diabetic retinopathy and macular edema in Malawi. PLOS ONE, 13(1). doi:10.1371/journal.pone.0190742
Automated Diagnosis of Fundus Camera Images for Diabetic Retinopathy for Treatment Referral
Pratt, H., Zheng, Y., Harding, S. P., Williams, B., Coenen, F., & Broadbent, D. (2018). Automated Diagnosis of Fundus Camera Images for Diabetic Retinopathy for Treatment Referral. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 28 (pp. 7). Retrieved from https://www.webofscience.com/
Hand-held Optical Coherence Tomography - A New Biomarker of Brain Swelling in Cerebral Malaria
Tu, Z., Sheth, V., Gormley, J., Manda, C., Proudlock, F. A., Seydel, K., . . . Gottlob, I. (2018). Hand-held Optical Coherence Tomography - A New Biomarker of Brain Swelling in Cerebral Malaria. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 59. Retrieved from https://www.webofscience.com/
OP60 Optimising Risk-Based Screening: The Case Of Diabetic Eye Disease
Sampson, C., James, M., Whynes, D., Eleuteri, A., & Harding, S. (2018). OP60 Optimising Risk-Based Screening: The Case Of Diabetic Eye Disease. International Journal of Technology Assessment in Health Care, 34(S1), 21. doi:10.1017/s0266462318001046
Putting Patients' Eyes Back into their Bodies: Implications of a Social Science Study of Screening and Diabetes Eye Care
Byrne, P., Broadbent, D. M., Thetford, C., Gabbay, M., Clark, P., Wang, A., & Harding, S. P. (2018). Putting Patients' Eyes Back into their Bodies: Implications of a Social Science Study of Screening and Diabetes Eye Care. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 28 (pp. 11). Retrieved from https://www.webofscience.com/
Visual Impairment in a Population Based Evaluation of People with Diabetes
Vazquez-Arango, P., Wang, A., Broadbent, D. M., Criddle, T., Stratton, I. M., Vora, J. P., & Harding, S. P. (2018). Visual Impairment in a Population Based Evaluation of People with Diabetes. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 28 (pp. 30). Retrieved from https://www.webofscience.com/
2017
Deformation velocity imaging using optical coherence tomography and its applications to the cornea
Lawman, S., Madden, P. W., Romano, V., Dong, Y., Mason, S., Williams, B., . . . Zheng, Y. (2017). Deformation velocity imaging using optical coherence tomography and its applications to the cornea. Biomedical Optics Express, 8(12), 5579-5593. doi:10.1364/BOE.8.005579
Spatial statistical modelling of capillary non-perfusion in the retina
MacCormick, I., Zheng, Y., Czanner, S., Zhao, Y., Diggle, P., Harding, S., & Czanner, G. (2017). Spatial statistical modelling of capillary non-perfusion in the retina. Scientific Reports, 7. doi:10.1038/s41598-017-16620-x
Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine
Harding, S. P., Eleuteri, A., Fisher, A. C., Broadbent, D. M., Garcia-Finana, M., Cheyne, C. P., . . . Seddon, D. (2017). Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine. Diabetologia, 60(11), 2174-2182. doi:10.1007/s00125-017-4386-0
Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy: Cross-sectional Analyses of Baseline Data of the EUROCONDOR Project
Santos, A. R., Ribeiro, L., Bandello, F., Lattanzio, R., Egan, C., Frydkjaer-Olsen, U., . . . Simo, R. (2017). Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy: Cross-sectional Analyses of Baseline Data of the EUROCONDOR Project. DIABETES, 66(9), 2503-2510. doi:10.2337/db16-1453
Ocular Complications in Survivors of the Ebola Outbreak in Guinea
Steptoe, P. J., Scott, J. T., Harding, S. P., Beare, N. A. V., Semple, M. G., Vandy, M. J., & Sahr, F. (2017). Ocular Complications in Survivors of the Ebola Outbreak in Guinea. AMERICAN JOURNAL OF OPHTHALMOLOGY, 181, 180. doi:10.1016/j.ajo.2017.05.029
Incidence and progression of diabetic retinopathy in Sub-Saharan Africa: A five year cohort study
Burgess, P. I., Harding, S. P., Garcia-Finana, M., Beare, N. A. V., Glover, S., Cohen, D. B., . . . Allain, T. J. (2017). Incidence and progression of diabetic retinopathy in Sub-Saharan Africa: A five year cohort study. PLoS One, 12(8). doi:10.1371/journal.pone.0181359
Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial.
Sivaprasad, S., Prevost, A. T., Vasconcelos, J. C., Riddell, A., Murphy, C., Kelly, J., . . . CLARITY Study Group. (2017). Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial.. Lancet (London, England), 389(10085), 2193-2203. doi:10.1016/s0140-6736(17)31193-5
Diagnostic performance of the handheld Radial Shape Discrimination test for detecting recent onset neovascular age-related macular degeneration
Knox, P. C., Vazquez, N. P., Harding, S. P., Heimann, H., & Czanner, G. (2017). Diagnostic performance of the handheld Radial Shape Discrimination test for detecting recent onset neovascular age-related macular degeneration. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Longitudinal Changes of Geographic Retinal Darkening in a Cohort of Ebola Survivors
Steptoe, P. J., Beare, N. V., Scott, J. T., Vandy, M. J., Harrison-Williams, L., Momorie, F., . . . Semple, M. G. (2017). Longitudinal Changes of Geographic Retinal Darkening in a Cohort of Ebola Survivors. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Performance of the handheld Radial Shape Discrimination test in Diabetic Macular Oedema suspects
Ku, J. Y., Harding, S. P., Broadbent, D. M., Stylianides, A., Criddle, T., & Knox, P. C. (2017). Performance of the handheld Radial Shape Discrimination test in Diabetic Macular Oedema suspects. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Automated Detection of Malarial Retinopathy in Digital Fundus Images for Improved Diagnosis in Malawian Children with Clinically Defined Cerebral Malaria
Joshi, V., Agurto, C., Barriga, S., Nemeth, S., Soliz, P., MacCormick, I. J., . . . Harding, S. P. (2017). Automated Detection of Malarial Retinopathy in Digital Fundus Images for Improved Diagnosis in Malawian Children with Clinically Defined Cerebral Malaria. Scientific Reports, 7. doi:10.1038/srep42703
A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study
Garcia-Finana, M., Hughes, D. M., Cheyne, C. P., Broadbent, D. M., Wang, A., Mobayen-Rahni, M., . . . Harding, S. P. (2017). A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Assessing lesion activity in neovascular AMD from colour images and optical coherence tomograms
Reeves, B. C., Harding, S. P., Peto, T., Muldrew, A., Scott, L., Rogers, C., & Chakravarthy, U. (2017). Assessing lesion activity in neovascular AMD from colour images and optical coherence tomograms. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Focal breakdown of the blood retinal barrier is associated with fatal brain swelling in paediatric cerebral malaria
MacCormick, I. J., Seydel, K., Potchen, M., Kampondeni, S., Heyderman, R., Molyneux, M., . . . Harding, S. P. (2017). Focal breakdown of the blood retinal barrier is associated with fatal brain swelling in paediatric cerebral malaria. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
In Reply.
Huang, A. J., Ganz, P., Grady, D., & Cummings, S. R. (2017). In Reply.. Menopause (New York, N.Y.), 24(1), 120. doi:10.1097/gme.0000000000000820
New insights into malaria retinopathy using optical coherence tomography
Gormley, J., Tu, Z., Sheth, V., Proudlock, F. A., Seydel, K., Taylor, T., . . . Gottlob, I. (2017). New insights into malaria retinopathy using optical coherence tomography. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Retinal Layer Location of Increased Retinal Thickness and Retinal Thinning on the cohort of the EUROCONDOR clinical trial
Costa, M. A., Ribeiro, L., Garcia-Arumi, J., Scanlon, P., Grauslund, J., Bandello, F., . . . Simo, R. (2017). Retinal Layer Location of Increased Retinal Thickness and Retinal Thinning on the cohort of the EUROCONDOR clinical trial. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY
Harding, S. P., Cheyne, C. P., Broadbent, D. M., Appelbe, D., Wang, A., Rahni, M., . . . Finana, M. G. (2017). SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 27 (pp. E126). Retrieved from https://www.webofscience.com/
Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease
Sahni, J. N., Czanner, G., Gutu, T., Taylor, S. A., Bennett, K. M., Wuerger, S. M., . . . Harding, S. P. (2017). Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease. Eye, 31(1), 97-106. doi:10.1038/eye.2016.259
Spatial distribution modelling of retinal lesions with application to retinal capillary non-perfusion in malarial retinopathy.
Czanner, G., MacCormick, I. J., Zheng, Y., Czanner, S., Zhao, Y., Diggle, P., & Harding, S. P. (2017). Spatial distribution modelling of retinal lesions with application to retinal capillary non-perfusion in malarial retinopathy.. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Subclinical changes on hand-held optical coherence tomography in apparently malaria retinopathy-negative patients with cerebral
Tu, Z., Gormley, J., Sheth, V., Proudlock, F. A., Seydel, K., Taylor, T., . . . Gottlob, I. (2017). Subclinical changes on hand-held optical coherence tomography in apparently malaria retinopathy-negative patients with cerebral. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
TOPICAL ADMINISTRATION OF SOMATOSTATIN AND BRIMONIDINE IN THE EARLY STAGES OF DIABETIC RETINOPATHY: RESULTS OF THE EUROCONDOR STUDY
Simo, R., Bandello, F., Egan, C. A., Garcia-Arumi, J., Gibson, J., Grauslund, J., . . . Cunha-Vaz, J. G. (2017). TOPICAL ADMINISTRATION OF SOMATOSTATIN AND BRIMONIDINE IN THE EARLY STAGES OF DIABETIC RETINOPATHY: RESULTS OF THE EUROCONDOR STUDY. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Topical administration of somatostatin and brimonidine in the early stages of diabetic retinopathy: results of the EUROCONDOR study
Simo, R., Bandello, F., Egan, C., Garcia-Arumi, J., Gibson, J., Grauslund, J., . . . Cunha-Vaz, J. (2017). Topical administration of somatostatin and brimonidine in the early stages of diabetic retinopathy: results of the EUROCONDOR study. In DIABETOLOGIA Vol. 60 (pp. S55-S56). Retrieved from https://www.webofscience.com/
2016
In Reply.
Bailey, T. G., Cable, T., Aziz, N., Dobson, R., Sprung, V. S., Low, D. A., & Jones, H. (2017). In Reply.. Menopause (New York, N.Y.), 24(1), 118-120. doi:10.1097/gme.0000000000000819
An effective variational model for simultaneous reconstruction and segmentation of blurred images
Williams, B. M., Spencer, J. A., Chen, K., Zheng, Y., & Harding, S. (2016). An effective variational model for simultaneous reconstruction and segmentation of blurred images. JOURNAL OF ALGORITHMS & COMPUTATIONAL TECHNOLOGY, 10(4), 244-264. doi:10.1177/1748301816660406
Detection of new neovascular AMD in at-risk eyes using a handheld radial shape discrimination test in a clinical population
Knox, P. C., Vazquez, N. P., Harding, S. P., & Heimann, H. (2016). Detection of new neovascular AMD in at-risk eyes using a handheld radial shape discrimination test in a clinical population. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 57. Retrieved from https://www.webofscience.com/
Relationship between foveal ellipsoid zone integrity and central visual function in age related macular degeneration
Vazquez, N. P., Harding, S. P., Heimann, H., & Knox, P. C. (2016). Relationship between foveal ellipsoid zone integrity and central visual function in age related macular degeneration. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 57. Retrieved from https://www.webofscience.com/
Stratifying the NHS Diabetic Eye Screening Programme: into the unknown?
Sampson, C. J., James, M., Broadbent, D. M., & Harding, S. P. (2016). Stratifying the NHS Diabetic Eye Screening Programme: into the unknown?. DIABETIC MEDICINE, 33(12), 1612-1614. doi:10.1111/dme.13192
Adult bacterial conjunctivitis: resistance patterns over 12 years in patients attending a large primary eye care centre in the UK
Silvester, A., Neal, T., Czanner, G., Briggs, M., Harding, S., & Kaye, S. (2016). Adult bacterial conjunctivitis: resistance patterns over 12 years in patients attending a large primary eye care centre in the UK. BMJ OPEN OPHTHALMOLOGY, 1(1). doi:10.1136/bmjophth-2016-000006
The Effectiveness, cost-effectiveness and acceptability of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual randomised balanced incomplete block triald
Reeves, B. C., Scott, L. J., Taylor, J., Hogg, R., Rogers, C. A., Wordsworth, S., . . . Chakravarthy, U. (2016). The Effectiveness, cost-effectiveness and acceptability of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual randomised balanced incomplete block triald. HEALTH TECHNOLOGY ASSESSMENT, 20(80), 1-+. doi:10.3310/hta20800
Cost-effectiveness of community versus hospital eye service follow-up for patients with quiescent treated age-related macular degeneration alongside the ECHoES randomised trial
Violato, M., Dakin, H., Chakravarthy, U., Reeves, B. C., Peto, T., Hogg, R. E., . . . Wordsworth, S. (2016). Cost-effectiveness of community versus hospital eye service follow-up for patients with quiescent treated age-related macular degeneration alongside the ECHoES randomised trial. BMJ OPEN, 6(10). doi:10.1136/bmjopen-2016-011121
Longitudinal Visuomotor Development in a Malaria Endemic Area: Cerebral Malaria and Beyond
Knox, P. C., MacCormick, I. J. C., Mbale, E., Malewa, M., Czanner, G., & Harding, S. P. (2016). Longitudinal Visuomotor Development in a Malaria Endemic Area: Cerebral Malaria and Beyond. PLoS ONE, 11(10). doi:10.1371/journal.pone.0164885
First Prospective Cohort Study of Diabetic Retinopathy from Sub-Saharan Africa: High Incidence and Progression of Retinopathy and Relationship to Human Immunodeficiency Virus Infection
Burgess, P. I., Harding, S. P., García-Fiñana, M., Beare, N. A. V., Msukwa, G., & Allain, T. J. (2016). First Prospective Cohort Study of Diabetic Retinopathy from Sub-Saharan Africa: High Incidence and Progression of Retinopathy and Relationship to Human Immunodeficiency Virus Infection. Ophthalmology, 123(9), 1919-1925. doi:10.1016/j.ophtha.2016.05.042
Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research
Hughes., Czanner, G., Cox, T., Bonnett, L., Harding, S., Marson, A., . . . Van der Hoek, M. (2016). Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research. Poster session presented at the meeting of 2016 MRC Festival of Medical Science. Liverpool.
Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual non-inferiority trial
Reeves, B. C., Scott, L. J., Taylor, J., Harding, S. P., Peto, T., Muldrew, A., . . . Chakravarthy, U. (2016). Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual non-inferiority trial. BMJ Open, 6(7). doi:10.1136/bmjopen-2015-010685
Automatic Enhancement & Analysis of Corneal Data from Ultra-High Resolution Optical Coherence Tomography (OCT)
Williams, B. M., Lawman, S., Kaye, S., Willoughby, C., Harding, S. P., Shen, Y., & Zheng, Y. (2016). Automatic Enhancement & Analysis of Corneal Data from Ultra-High Resolution Optical Coherence Tomography (OCT). Poster session presented at the meeting of DEVS Away Day 2016.
High Resolution Corneal and Single Pulse Imaging with Line Field Spectral Domain Optical Coherence Tomography
Lawman, S., Dong, Y., Williams, B. M., Romano, V., Kaye, S., Harding, S. P., . . . Zheng, Y. (2016). High Resolution Corneal and Single Pulse Imaging with Line Field Spectral Domain Optical Coherence Tomography. Optics Express, 24(11), 12395-12405. doi:10.1364/OE.24.012395
Endothelial Dysfunction in People with Diabetes in Sub-Saharan Africa: Relationships with Retinopathy Progression and Mortality
Burgess, P., Allain, T. J., Msukwa, G., Kayange, P., Mbewe, F., Garcia-Finana, M., & Harding, S. (2016). Endothelial Dysfunction in People with Diabetes in Sub-Saharan Africa: Relationships with Retinopathy Progression and Mortality. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 57. Retrieved from https://www.webofscience.com/
Comparing the performance of three retinal cameras in detecting malarial retinopathy in pediatric cerebral malaria in Malawi
Joshi, V. S., Nemeth, S. C., Soliz, P., Taylor, T. E., MacCormick, I., Harding, S. P., . . . Lewallen, S. (2016). Comparing the performance of three retinal cameras in detecting malarial retinopathy in pediatric cerebral malaria in Malawi. In Association for Research in Vision and Ophthalmology. Seattle.
Modulation of cathepsin L expression and NF-kB signalling pathway effectors by advanced glycation end-products in retinal pigment epithelial cells
Mahmud, N. M., Sharif, U., Kay, P., Kamalden, T. A. F. T., Yang, Y. C., Harding, S. P., & Paraoan, L. (2016). Modulation of cathepsin L expression and NF-kB signalling pathway effectors by advanced glycation end-products in retinal pigment epithelial cells. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/
COMPARING HEALTH PROFESSIONALS' AND PATIENT PERSPECTIVES OF INDIVIDUALISED SCREENING INTERVALS FOR DIABETIC RETINOPATHY SCREENING
Thetford, C., Byrne, P., Gabbay, M., Harding, S. P., Broadbent, D., & Roberts, J. (2016). COMPARING HEALTH PROFESSIONALS' AND PATIENT PERSPECTIVES OF INDIVIDUALISED SCREENING INTERVALS FOR DIABETIC RETINOPATHY SCREENING. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E102-E103). Retrieved from https://www.webofscience.com/
HEALTH-RELATED QUALITY OF LIFE OF PEOPLE ATTENDING SCREENING FOR DIABETIC RETINOPATHY WITHIN A TRIAL SETTING
Sampson, C., James, M., Van Eker, D., Szmyt, D., & Harding, S. P. (2016). HEALTH-RELATED QUALITY OF LIFE OF PEOPLE ATTENDING SCREENING FOR DIABETIC RETINOPATHY WITHIN A TRIAL SETTING. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E100-E101). Retrieved from https://www.webofscience.com/
MICRO-COSTING DIABETIC EYE SCREENING: ESTIMATION OF PERSONAL EXPENSE, ATTENDANCE AND HEALTH CARE RESOURCE USE
James, M., Sampson, C. J., Van Eker, D., Szmyt, D., & Harding, S. P. (2016). MICRO-COSTING DIABETIC EYE SCREENING: ESTIMATION OF PERSONAL EXPENSE, ATTENDANCE AND HEALTH CARE RESOURCE USE. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E90). Retrieved from https://www.webofscience.com/
OSCILLATORY POTENTIAL: A MORE SENSITIVE MARKER FOR DIABETIC MACULOPATHY PROGRESSION?
Raj, A., Czanner, G., Sahni, J., Campa, C., Hagan, R., & Harding, S. P. (2016). OSCILLATORY POTENTIAL: A MORE SENSITIVE MARKER FOR DIABETIC MACULOPATHY PROGRESSION?. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E91). Retrieved from https://www.webofscience.com/
Comparison of the effectiveness of three retinal camera technologies for malarial retinopathy detection in Malawi
Soliz, P., Nemeth, S. C., Barriga, E. S., Harding, S. P., Lewallen, S., Taylor, T. E., . . . Joshi, V. S. (2016). Comparison of the effectiveness of three retinal camera technologies for malarial retinopathy detection in Malawi. In Proc. SPIE 9693, Ophthalmic Technologies XXVI Vol. 9693. SPIE - International Society for Optics and Photonics. doi:10.1117/12.2213282
Automated detection of retinal whitening in malarial retinopathy
Joshi, V., Agurto, C., Barriga, S., Nemeth, S., Soliz, P., MacCormick, I., . . . Harding, S. (2016). Automated detection of retinal whitening in malarial retinopathy. In G. D. Tourassi, & S. G. Armato (Eds.), SPIE Proceedings Vol. 9785 (pp. 97852G). SPIE. doi:10.1117/12.2217188
Vessel discoloration detection in malarial retinopathy
Agurto, C., Nemeth, S., Barriga, S., Soliz, P., MacCormick, I., Taylor, T., . . . Joshi, V. (2016). Vessel discoloration detection in malarial retinopathy. In G. D. Tourassi, & S. G. Armato (Eds.), SPIE Proceedings Vol. 9785 (pp. 978519). SPIE. doi:10.1117/12.2216917
10 YEAR OBSERVATIONAL STUDY OF PATIENT RELATED OUTCOMES DURING EXPANSION TO FULL POPULATION COVERAGE OF A SYSTEMATIC DIABETES EYE CARE PROGRAMME - THE LIVERPOOL DIABETIC EYE STUDY
Harding, S. P., Sampson, C., Cheyne, C. P., Broadbent, D. M., Stratton, I. M., Wang, A., & Garcia Finana, M. (2016). 10 YEAR OBSERVATIONAL STUDY OF PATIENT RELATED OUTCOMES DURING EXPANSION TO FULL POPULATION COVERAGE OF A SYSTEMATIC DIABETES EYE CARE PROGRAMME - THE LIVERPOOL DIABETIC EYE STUDY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E98). Retrieved from https://www.webofscience.com/
10 year observational study of patient related outcomes during expansion to full population coverage of a systematic diabetes eye care programme - the Liverpool Diabetic Eye Study
Harding, S. P., Sampson, C., Cheyne, C., Broadbent, D., Wang, A., Mobayen-Rahni, M., . . . Finana, M. G. (2016). 10 year observational study of patient related outcomes during expansion to full population coverage of a systematic diabetes eye care programme - the Liverpool Diabetic Eye Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 57. Retrieved from https://www.webofscience.com/
BUILDING A DYNAMIC FUNCTIONAL CLINICAL DATA WAREHOUSE (CDW) FOR PERSONALISED HEALTH CARE - LESSONS FROM THE INDIVIDUALISED SCREENING FOR DIABETIC RETINOPATHY (ISDR) STUDY
Wang, A., Alshukri, A., Rahni, M. M., Fisher, A. C., Broadbent, D. M., Appelbe, D., & Harding, S. P. (2016). BUILDING A DYNAMIC FUNCTIONAL CLINICAL DATA WAREHOUSE (CDW) FOR PERSONALISED HEALTH CARE - LESSONS FROM THE INDIVIDUALISED SCREENING FOR DIABETIC RETINOPATHY (ISDR) STUDY. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/
Convolutional Neural Networks for Diabetic Retinopathy
Pratt, H., Coenen, F., Broadbent, D. M., Harding, S. P., & Zheng, Y. (2016, July 6). Convolutional Neural Networks for Diabetic Retinopathy. In Procedia Computer Science Vol. 90 (pp. 200-205). Loughbrough University: Elsevier. doi:10.1016/j.procs.2016.07.014
The design and implementation of a study to investigate the effectiveness of community vs hospital eye service follow-up for patients with neovascular age-related macular degeneration with quiescent disease
Taylor, J., Scott, L. J., Rogers, C. A., Muldrew, A., O'Reilly, D., Wordsworth, S., . . . Reeves, B. C. (2016). The design and implementation of a study to investigate the effectiveness of community vs hospital eye service follow-up for patients with neovascular age-related macular degeneration with quiescent disease. EYE, 30(1), 68-78. doi:10.1038/eye.2015.170
2015
Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR): a case study in the use of automated systems in trials
Appelbe, D., Broadbent, D., Mobayen-Rahni, M., Eleuteri, A., Bennett, A., Moitt, T., . . . Harding, S. (2015). Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR): a case study in the use of automated systems in trials. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O59
Defining response to anti-VEGF therapies in neovascular AMD.
Amoaku, W. M., Chakravarthy, U., Gale, R., Gavin, M., Ghanchi, F., Gibson, J., . . . Yang, Y. (2015). Defining response to anti-VEGF therapies in neovascular AMD.. Eye (London, England), 29(10), 1397-1398. doi:10.1038/eye.2015.159
Grading fluorescein angiograms in malarial retinopathy
MacCormick, I. J. C., Maude, R. J., Beare, N. A. V., Borooah, S., Glover, S., Parry, D., . . . Harding, S. P. (2015). Grading fluorescein angiograms in malarial retinopathy. MALARIA JOURNAL, 14. doi:10.1186/s12936-015-0897-7
A New Method of Blind Deconvolution for Colour Fundus Retinal Images
Williams, B. M., Chen, K., Harding, S. P., & Zheng, Y. (2015, October 9). A New Method of Blind Deconvolution for Colour Fundus Retinal Images. In Proceedings of the Ophthalmic Medical Image Analysis Second International Workshop (pp. 129-136). University of Iowa. doi:10.17077/omia.1036
Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding
Moxon, C. A., Chisala, N. V., Mzikamanda, R., MacCormick, I., Harding, S., Downey, C., . . . Toh, C. -H. (2015). Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 13(9), 1653-1664. doi:10.1111/jth.13060
Early Detection of Diabetic Retinopathy using Personalised Longitudinal Discriminant Analysis
Hughes, D., Czanner, G., Komarek, A., Harding, S., & Garcia Finana, M. (2015). Early Detection of Diabetic Retinopathy using Personalised Longitudinal Discriminant Analysis. Utrecht, Holland.
Delayed visual evoked potentials in children with Plasmodium falciparum malaria and reduced consciousness
Beare, N., Falsini, B., Lochhead, J., Molyneux, M., Taylor, T., Harding, S., & Southern, C. (n.d.). Delayed visual evoked potentials in children with Plasmodium falciparum malaria and reduced consciousness. Journal of Pediatric Neurology, 06(01), 017-024. doi:10.1055/s-0035-1557433
Retinal Fundus Image Deconvolution
Williams, B. M., Zheng, Y., Chen, K., & Harding, S. (2015). Retinal Fundus Image Deconvolution. Poster session presented at the meeting of Mathematical Imaging with Biomedical Applications Workshop. CMIT, University of Liverpool.
Personalised Longitudinal Discriminant Analysis for Early Detection of Diabetic Retinopathy
Hughes, D., Czanner, G., Cheyne, C., Komarek, A., Harding, S., & Garcia Finana, M. (2015). Personalised Longitudinal Discriminant Analysis for Early Detection of Diabetic Retinopathy. Poster session presented at the meeting of ITM Research Day. University of Liverpool.
A new constrained total variational deblurring model and its fast algorithm
Williams, B. M., Chen, K., & Harding, S. P. (2015). A new constrained total variational deblurring model and its fast algorithm. NUMERICAL ALGORITHMS, 69(2), 415-441. doi:10.1007/s11075-014-9904-2
Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography
Boonarpha, N., Zheng, Y., Stangos, A. N., Lu, H., Raj, A., Czanner, G., . . . Nair-Sahni, J. (2015). Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography. INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 8(3), 484-491. doi:10.3980/j.issn.2222-3959.2015.03.09
Severity of Retinopathy Parallels the Degree of Parasite Sequestration in the Eyes and Brains of Malawian Children With Fatal Cerebral Malaria
Barrera, V., Hiscott, P. S., Craig, A. G., White, V. A., Milner, D. A., Beare, N. A. V., . . . Harding, S. P. (2015). Severity of Retinopathy Parallels the Degree of Parasite Sequestration in the Eyes and Brains of Malawian Children With Fatal Cerebral Malaria. Journal of Infectious Diseases, 211(12), 1977-1986. doi:10.1093/infdis/jiu592
Defining response to anti-VEGF therapies in neovascular AMD
Amoaku, W. M., Chakravarthy, U., Gale, R., Gavin, M., Ghanchi, F., Gibson, J., . . . Yang, Y. (2015). Defining response to anti-VEGF therapies in neovascular AMD. EYE, 29(6), 721-731. doi:10.1038/eye.2015.48
Automated Detection of Vessel Abnormalities on Fluorescein Angiogram in Malarial Retinopathy
Zhao, Y., MacCormick, I., Parry, D., Beare, N., Harding, S., & Zheng, Y. (2015). Automated Detection of Vessel Abnormalities on Fluorescein Angiogram in Malarial Retinopathy. Scientific Reports, 5. doi:10.1038/srep11154
Automated Detection of Leakage in Fluorescein Angiography Images with Application to Malarial Retinopathy
Zhao, Y., MacCormick, I. J. C., Parry, D., Leach, S., Beare, N. A. V., Harding, S., & Zheng, Y. (2015). Automated Detection of Leakage in Fluorescein Angiography Images with Application to Malarial Retinopathy. Scientific Reports, 5. doi:10.1038/srep10425
Individualised risk-based screening for sight threatening diabetic retinopathy - the Liverpool Risk Calculation Engine
Harding, S. P., Eleuteri, A., Broadbent, D. M., van der Hoek, M., Cheyne, C. P., Wang, A., . . . Fisher, A. C. (2015). Individualised risk-based screening for sight threatening diabetic retinopathy - the Liverpool Risk Calculation Engine. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Effects of advanced glycation end-products (AGEs) on retinal pigment epithelial (RPE) cells lysosomal function: implications for age-related macular degeneration (AMD)
Paraoan, L., Sharif, U., Kay, P., Grierson, I., Yang, Y. C., & Harding, S. (2015). Effects of advanced glycation end-products (AGEs) on retinal pigment epithelial (RPE) cells lysosomal function: implications for age-related macular degeneration (AMD). Poster session presented at the meeting of Unknown Conference.
Long-term visual follow-up in children with malarial retinopathy
Knox, P. C., MacCormack, I. J. C., Mallewa, M., & Harding, S. P. (2015). Long-term visual follow-up in children with malarial retinopathy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Stability of performance of a handheld radial shape discrimination test in patients at risk of developing neovascular AMD
Vazquez, N. P., Harding, S. P., Heimann, H., & Knox, P. C. (2015). Stability of performance of a handheld radial shape discrimination test in patients at risk of developing neovascular AMD. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Retinal Vessel Segmentation: An Efficient Graph Cut Approach with Retinex and Local Phase (vol 10, e0122332, 2015)
Zhao, Y., Liu, Y., Wu, X., Harding, S. P., & Zheng, Y. (2015). Retinal Vessel Segmentation: An Efficient Graph Cut Approach with Retinex and Local Phase (vol 10, e0122332, 2015). PLOS ONE, 10(4). doi:10.1371/journal.pone.0127486
Abstracts from the 25th Meeting of the European Association for the Study of Diabetes Eye Complications Study Group (EASDec).
Abstracts from the 25th Meeting of the European Association for the Study of Diabetes Eye Complications Study Group (EASDec). (2015). In European journal of ophthalmology Vol. 25 (pp. e7-e30). doi:10.5301/ejo.5000612
Retinal Vessel Segmentation: An Efficient Graph Cut Approach with Retinex and Local Phase
Zhao, Y., Liu, Y., Wu, X., Harding, S., & Zheng, Y. (2015). Retinal Vessel Segmentation: An Efficient Graph Cut Approach with Retinex and Local Phase. PLOS One, 10(4). doi:10.1371/journal.pone.0122332
Automated Vessel Segmentation Using Infinite Perimeter Active Contour Model with Hybrid Region Information with Application to Retinal Images
Zhao, Y., Rada, L., Chen, K., Harding, S., & Zheng, Y. (2015). Automated Vessel Segmentation Using Infinite Perimeter Active Contour Model with Hybrid Region Information with Application to Retinal Images. IEEE Transactions on Medical Imaging, 34(9), 1797-1807. doi:10.1109/TMI.2015.2409024
INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY – THE LIVERPOOL RISK CALCULATION ENGINE
Harding, S. P., Eleuteri, A., Broadbent, D. M., Van der Hoek, M., Cheyne, C., Wang, A., . . . Fisher, A. C. (2015, June 26). INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY – THE LIVERPOOL RISK CALCULATION ENGINE. In European Journal of Ophthalmology Vol. 25 (pp. e7-e30). Turin. doi:10.5301/ejo.5000612
Introducing personalised risk based intervals in screening for diabetic retinopathy: the ISDR study
Broadbent, D. M., Bennet, A., Appelbe, D., Wang, A., Van der Hoek, M., Fisher, A. C., & Harding, S. P. (2015, June 26). Introducing personalised risk based intervals in screening for diabetic retinopathy: the ISDR study. In European Journal of Ophthalmology Vol. 25 (pp. e7-e30). Turin. doi:10.5301/ejo.5000612
Patient perspectives of acceptability of risk-based individualised diabetic retinopathy
Byrne, P., Thetford, C., Gabbay, M., Wang, A., Broadbent, D. M., & Harding, S. P. (2015, June 26). Patient perspectives of acceptability of risk-based individualised diabetic retinopathy. In European Journal of Ophthalmology Vol. 25 (pp. e7-e30). Turin.
A New Study of Blind Deconvolution with Implicit Incorporation of Nonnegativity Constraints
Chen, K., Harding, S. P., Williams, B. M., & Zheng, Y. (2015). A New Study of Blind Deconvolution with Implicit Incorporation of Nonnegativity Constraints. International Journal of Computational Mathematics, 2015, 1-17. doi:10.1155/2015/860263
COST-EFFECTIVENESS OF A RISK-BASED SCREENING PROGRAMME FOR DIABETIC RETINOPATHY: A MODELLING APPROACH
Sampson, C., James, M., Fisher, A. C., & Harding, S. P. (2015). COST-EFFECTIVENESS OF A RISK-BASED SCREENING PROGRAMME FOR DIABETIC RETINOPATHY: A MODELLING APPROACH. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E13. Retrieved from https://www.webofscience.com/
Comparing the effectiveness of single posterior pole retinal images against binocular indirect ophthalmoscopic exam in detecting retinal hemorrhages in pediatric cerebral malaria
Nemeth, S. C., MacCormack, I. J. C., Harding, S. P., Lewallen, S., Taylor, T. E., Soliz, P., & Joshi, V. S. (2015). Comparing the effectiveness of single posterior pole retinal images against binocular indirect ophthalmoscopic exam in detecting retinal hemorrhages in pediatric cerebral malaria. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Effects of advanced glycation end-products (AGEs) on retinal pigment epithelial (RPE) cells lysosomal function: implications for age-related macular degeneration (AMD)
Paraoan, L. I., Sharif, U., Kay, P., Grierson, I., Yang, Y. C., & Harding, S. (2015). Effects of advanced glycation end-products (AGEs) on retinal pigment epithelial (RPE) cells lysosomal function: implications for age-related macular degeneration (AMD). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(7). Retrieved from https://www.webofscience.com/
INCIDENCE AND PROGRESSION OF RETINOPATHY AND VISUAL IMPAIRMENT IN PEOPLE WITH DIABETES IN SUB-SAHARAN AFRICA; RELATIONSHIP WITH POPULATION SPECIFIC VARIABLES
Burgess, P., Allain, J., Msukwa, G., Pindani, C., Mkangadzula, O., Garcia-Finana, M., & Harding, S. P. (2015). INCIDENCE AND PROGRESSION OF RETINOPATHY AND VISUAL IMPAIRMENT IN PEOPLE WITH DIABETES IN SUB-SAHARAN AFRICA; RELATIONSHIP WITH POPULATION SPECIFIC VARIABLES. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E7-E8. Retrieved from https://www.webofscience.com/
INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY: THE LIVERPOOL RISK CALCULATION ENGINE
Harding, S. P., Eleuteri, A., Broadbent, D. M., van der Hoek, M., Cheyne, C. P., Stratton, I. M., & Fisher, A. C. (2015). INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY: THE LIVERPOOL RISK CALCULATION ENGINE. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E12-E13. Retrieved from https://www.webofscience.com/
INTRODUCING PERSONALISED RISK BASED INTERVALS IN SCREENING FOR DIABETIC RETINOPATHY: THE ISDR STUDY
Broadbent, D. M., Harding, S. P., Garcia-Finana, M., Fisher, A. C., Bennett, A., Appelbe, D. E., & Wang, A. (2015). INTRODUCING PERSONALISED RISK BASED INTERVALS IN SCREENING FOR DIABETIC RETINOPATHY: THE ISDR STUDY. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E20-E21. Retrieved from https://www.webofscience.com/
Impact of hypertension on choroidal thickness in central serous chorioretinopathy
Boonarpha, N., Zheng, Y., Czanner, G., Harding, S. P., & Sahni, J. (2015). Impact of hypertension on choroidal thickness in central serous chorioretinopathy. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Incidence and progression of retinopathy and visual impairment in people with diabetes in Sub-Saharan Africa; relationship with population specific variables
Burgess, P., Allain, T. J., Msukwa, G., Pindani, C., Mbewe, F., Garcia-Finana, M., & Harding, S. P. (2015). Incidence and progression of retinopathy and visual impairment in people with diabetes in Sub-Saharan Africa; relationship with population specific variables. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR): a case study in the use of automated systems in trials
Appelbe, D., Broadbent, D., Mobayen-Rahni, M., Eleuteri, A., Bennett, A., Moitt, T., . . . Harding, S. (2015). Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR): a case study in the use of automated systems in trials. Trials, 16(Suppl 2), O59.
PATIENT PERSPECTIVES OF ACCEPTABILITY OF RISK-BASED INDIVIDUALIZED DIABETIC RETINOPATHY
Byrne, P., Thetford, C., Gabbay, M., Wang, A., Broadbent, D., & Harding, S. P. (2015). PATIENT PERSPECTIVES OF ACCEPTABILITY OF RISK-BASED INDIVIDUALIZED DIABETIC RETINOPATHY. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E7. Retrieved from https://www.webofscience.com/
Safety and acceptability of an organic light emitting diode (OLED) sleep mask for the treatment of retinal diseases: INSIGHT Study
Czanner, G., Gutu, T., Harding, S. P., Holland, M., Grierson, I., Bennett, K., . . . Sahni, J. (2015). Safety and acceptability of an organic light emitting diode (OLED) sleep mask for the treatment of retinal diseases: INSIGHT Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 56. Retrieved from https://www.webofscience.com/
2014
High prevalence in Malawi of sight-threatening retinopathy and visual impairment caused by diabetes: identification of population-specific targets for intervention
Burgess, P. I., Allain, T. J., Garcia-Finana, M., Beare, N. A. V., Msukwa, G., & Harding, S. P. (2014). High prevalence in Malawi of sight-threatening retinopathy and visual impairment caused by diabetes: identification of population-specific targets for intervention. DIABETIC MEDICINE, 31(12), 1643-1650. doi:10.1111/dme.12492
Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial
Dakin, H. A., Wordsworth, S., Rogers, C. A., Abangma, G., Raftery, J., Harding, S. P., . . . Investigators, I. V. A. N. S. (2014). Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial. BMJ Open, 4(7). doi:10.1136/bmjopen-2014-005094
Improving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study.
Prescott, G., Sharp, P., Goatman, K., Scotland, G., Fleming, A., Philip, S., . . . Olson, J. (2014). Improving the cost-effectiveness of photographic screening for diabetic macular oedema: a prospective, multi-centre, UK study.. British Journal of Ophthalmology, 98, 1042-1049. doi:10.1136/bjophthalmol-2013-304338
A Comprehensive Texture Segmentation Framework for Segmentation of Capillary Non-Perfusion Regions in Fundus Fluorescein Angiograms
Zheng, Y., Kwong, M. T., MacCormick, I. J. C., Beare, N. A. V., & Harding, S. P. (2014). A Comprehensive Texture Segmentation Framework for Segmentation of Capillary Non-Perfusion Regions in Fundus Fluorescein Angiograms. PLOS ONE, 9(4). doi:10.1371/journal.pone.0093624
A Comprehensive Texture Segmentation Framework for Segmentation of Capillary Non-Perfusion Regions in Fundus Fluorescein Angiograms
Zheng, Y., Kwong, M. T., MacCormick, I. J. C., Beare, N. A. V., & Harding, S. P. (n.d.). A Comprehensive Texture Segmentation Framework for Segmentation of Capillary Non-Perfusion Regions in Fundus Fluorescein Angiograms. PLoS ONE, 9(4), e93624. doi:10.1371/journal.pone.0093624
Alterations in serum vascular endothelial growth factor after intraocular administration of antiVEGF drugs, is there an association with safety outcomes?
Chakravarthy, U., Rogers, C., Reeves, B., Scott, L., Harding, S. P., Downes, S. M., & Lotery, A. (2014). Alterations in serum vascular endothelial growth factor after intraocular administration of antiVEGF drugs, is there an association with safety outcomes?. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from https://www.webofscience.com/
Cerebral malaria in children: using the retina to study the brain
MacCormick, I. J. C., Beare, N. A. V., Taylor, T. E., Barrera, V., White, V. A., Hiscott, P., . . . Harding, S. P. (2014). Cerebral malaria in children: using the retina to study the brain. BRAIN, 137, 2119-2142. doi:10.1093/brain/awu001
Cysteine proteases expression and secretion by retinal pigmented epithelium (RPE)
Sharif, U., Butler, J., Yang, Y. C., Grierson, I., Harding, S. P., & Paraoan, L. I. (2014). Cysteine proteases expression and secretion by retinal pigmented epithelium (RPE). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(13). Retrieved from https://www.webofscience.com/
Gastrointestinal serious adverse events in patients treated with intraocular ranibizumab or bevacizumab for age-related choroidal neovascularisation, what do the recent trials tell us?
Scott, L., Chakravarthy, U., Nash, R., Downes, S. M., Harding, S. P., Reeves, B., & Rogers, C. (2014). Gastrointestinal serious adverse events in patients treated with intraocular ranibizumab or bevacizumab for age-related choroidal neovascularisation, what do the recent trials tell us?. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from https://www.webofscience.com/
Morphological features and determinants of new geographic atrophy developing in participants in the IVAN trial
Picton, F., Muldrew, K. A., Reeves, B., Rogers, C., Harding, S. P., Chakravarthy, U., & Peto, T. (2014). Morphological features and determinants of new geographic atrophy developing in participants in the IVAN trial. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from https://www.webofscience.com/
Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria
MacCormick, I. J. C., Beare, N. A. V., Taylor, T. E., Barrera, V., White, V. A., Hiscott, P., . . . Harding, S. P. (2014). Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria. BRAIN, 137. doi:10.1093/brain/awu146
Retinal Vascular Leakage is Associated with Death in Cerebral Malaria in African Children
Harding, S. P., MacCormick, I. J., Glover, S., Mallewa, M., Taylor, T., & Molyneux, M. E. (2014). Retinal Vascular Leakage is Associated with Death in Cerebral Malaria in African Children. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from https://www.webofscience.com/
Visual acuity by responder status in the IVAN clinical trial
Lotery, A., Scott, L., Harding, S. P., Reeves, B., Rogers, C., & Chakravarthy, U. (2014). Visual acuity by responder status in the IVAN clinical trial. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 55. Retrieved from https://www.webofscience.com/
Waist-to-hip ratio, dyslipidemia, glycemic levels, blood pressure and depressive symptoms among diabetic and non-diabetic Chinese women: a cross-sectional study.
Zheng, Y., Sun, Q., Chen, K., Yan, W., Pan, C., Lu, J., . . . Mu, Y. (2014). Waist-to-hip ratio, dyslipidemia, glycemic levels, blood pressure and depressive symptoms among diabetic and non-diabetic Chinese women: a cross-sectional study.. PloS one, 9(10), e109765. doi:10.1371/journal.pone.0109765
2013
Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration
Ansari, M., Mckeigue, P. M., Skerka, C., Hayward, C., Rudan, I., Vitart, V., . . . Wright, A. F. (2013). Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. HUMAN MOLECULAR GENETICS, 22(23), 4857-4869. doi:10.1093/hmg/ddt336
Pharmacogenetic Associations with Vascular Endothelial Growth Factor Inhibition in Participants with Neovascular Age-related Macular Degeneration in the IVAN Study
Lotery, A. J., Gibson, J., Cree, A. J., Downes, S. M., Harding, S. P., Rogers, C. A., . . . Chakravarthy, U. (2013). Pharmacogenetic Associations with Vascular Endothelial Growth Factor Inhibition in Participants with Neovascular Age-related Macular Degeneration in the IVAN Study. OPHTHALMOLOGY, 120(12), 2637-2643. doi:10.1016/j.ophtha.2013.07.046
Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study
Olson, J., Sharp, P., Goatman, K., Prescott, G., Scotland, G., Fleming, A., . . . Wharton, H. (2013). Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study. HEALTH TECHNOLOGY ASSESSMENT, 17(51), 1-+. doi:10.3310/hta17510
Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial
Chakravarthy, U., Harding, S. P., Rogers, C. A., Downes, S. M., Lotery, A. J., Culliford, L. A., & Reeves, B. C. (2013). Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial. LANCET, 382(9900), 1258-1267. doi:10.1016/S0140-6736(13)61501-9
Mathematical deblurring of images for non-blind and blind restoration
Williams, B. M., Chen, K., Zheng, Y., & Harding, S. P. (2013). Mathematical deblurring of images for non-blind and blind restoration. In 25th Biennial Numerical Analysis Conference. University of Strathclyde.
Living with age-related macular degeneration treatment: Patient experiences of being treated with ranibizumab (Lucentis)<sup>(R)</sup> intravitreal injections
Thetford, C., Hodge, S., Harding, S., Taylor, S., & Knox, P. C. (2013). Living with age-related macular degeneration treatment: Patient experiences of being treated with ranibizumab (Lucentis)<sup>(R)</sup> intravitreal injections. British Journal of Visual Impairment, 31(2), 89-101. doi:10.1177/0264619613481778
Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review
Burgess, P. I., MacCormick, I. J. C., Harding, S. P., Bastawrous, A., Beare, N. A. V., & Garner, P. (2013). Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review. DIABETIC MEDICINE, 30(4), 399-412. doi:10.1111/j.1464-5491.2012.03756.x
Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review.
Burgess, P. I., MacCormick, I. J. C., Harding, S. P., Bastawrous, A., Beare, N. A. V., & Garner, P. (2013). Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review.. Diabetic medicine : a journal of the British Diabetic Association, 30(4), 399-412. doi:10.1111/j.1464-5491.2012.03756.x
Seven new loci associated with age-related macular degeneration
Fritsche, L. G., Chen, W., Schu, M., Yaspan, B. L., Yu, Y., Thorleifsson, G., . . . Abecasis, G. R. (2013). Seven new loci associated with age-related macular degeneration. NATURE GENETICS, 45(4), 433-439. doi:10.1038/ng.2578
Computerized Assessment of Intraretinal and Subretinal Fluid Regions in Spectral-Domain Optical Coherence Tomography Images of the Retina
Zheng, Y., Sahni, J., Campa, C., Stangos, A. N., Raj, A., & Harding, S. P. (2013). Computerized Assessment of Intraretinal and Subretinal Fluid Regions in Spectral-Domain Optical Coherence Tomography Images of the Retina. AMERICAN JOURNAL OF OPHTHALMOLOGY, 155(2), 277-286. doi:10.1016/j.ajo.2012.07.030
Cost-effectiveness of ranibizumab and bevacizumab for neovascular age-related macular degeneration: 1 year IVAN results.
Rogers, C. A., Dakin, H. A., Wordsworth, S., Abangma, G., Raftery, J., Harding, S. P., . . . Reeves, B. C. (2013). Cost-effectiveness of ranibizumab and bevacizumab for neovascular age-related macular degeneration: 1 year IVAN results.. Invest Ophtalmol Vis Sci, 54, 373.
Cross-sectional analysis of pro- and anti-saccade development in retinopathy-confirmed cerebral malaria.
Knox, P. C., MacCormick, I. J. C., Watson, R. I., Mallewa, M., & Harding, S. P. (2013). Cross-sectional analysis of pro- and anti-saccade development in retinopathy-confirmed cerebral malaria.. Invest Ophthalmol Vis Sci, 54, 175.
Improving the analysis of choroidal laser doppler flowmetry measurements; application in patients with retinal diseases.
Boonarpha, N., Czanner, G., Raj, A., Zheng, Y., Geiser, M., Riva, C., . . . Harding, S. (2013). Improving the analysis of choroidal laser doppler flowmetry measurements; application in patients with retinal diseases.. Invest Ophthalmol Vis Sci, 54, 5871.
Intensity of parasite sequestration in retinal vessels correlates with severity of retinopathy in malawian children with cerebral malaria: a histopathological study.
Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Intensity of parasite sequestration in retinal vessels correlates with severity of retinopathy in malawian children with cerebral malaria: a histopathological study..
Living with AMD treatment: Patient experiences of being treated with Ranibizumab (Lucentis) intravitreal injections
Thetford, C., Hodge, S., Harding, S., Taylor, S., & Knox, P. (2013). Living with AMD treatment: Patient experiences of being treated with Ranibizumab (Lucentis) intravitreal injections. British Journal of Visual Impairment.
Malaria pigment (hemozoin) and extravasated fibrinogen are associated with retinal vessel leakage and hemorrhages in malawian children with cerebral malaria.
Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Malaria pigment (hemozoin) and extravasated fibrinogen are associated with retinal vessel leakage and hemorrhages in malawian children with cerebral malaria..
Modelling of longitudinal outcomes with highly skewed distributions: applications in the IVAN trial
Nash, R., Scott, L., Chakravarthy, U., Harding, S. P., Reeves, B. C., & Rogers, C. A. (2013). Modelling of longitudinal outcomes with highly skewed distributions: applications in the IVAN trial. Trials, 14(Suppl 1), O39. doi:10.1186/1745-6215-14-s1-o39
Patterns of leakage from retinal vessels in pediatric cerebral malaria.
Harding, S. P., MacCormick, I. J. C., Beare, N. A. V., Mallewa, M., Glover, S. J., Taylor, T. E., & Molyneux, M. E. (2013). Patterns of leakage from retinal vessels in pediatric cerebral malaria..
Pharmacogenetic associations in neovascular age-related macular degeneration. Results from the IVAN study.
Lotery, A. J., Gibson, J., Cree, A. J., Downes, S. M., Harding, S. P., Rogers, C. A., . . . Chakravarthy, U. (2013). Pharmacogenetic associations in neovascular age-related macular degeneration. Results from the IVAN study.. Invest Ophthalmol Vis Sci, 54, 6185.
Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study.
Lotery, A. J., Gibson, J., Cree, A. J., Downes, S. M., Harding, S. P., Rogers, C. A., . . . Chakravarthy, U. (2013). Pharmacogenetic associations with vascular endothelial growth factor inhibition in participants with neovascular age-related macular degeneration in the IVAN Study.. Ophthalmology.
Retinal microvascular dysfunction in paediatric cerebral malaria is associated with death and neurological sequelae.
MacCormick, I., Glover, S. J., Beare, N., Czanner, G., Mallewa, M., Taylor, T. E., . . . Harding, S. (2013). Retinal microvascular dysfunction in paediatric cerebral malaria is associated with death and neurological sequelae..
Somatostatin replacement: a new strategy for treating diabetic retinopathy
Hernández, C., Simó, R., & for the Early Treatment of Diabetic Retinopathy (EUROCONDOR), E. C. (2013). Somatostatin replacement: a new strategy for treating diabetic retinopathy. Current Medicinal Chemistry, 20(26), 3251-3257.
The relationship between haemorrhage and OCT signs and the likelihood of neovascular amd being active during follow-up: Data from the IVAN study.
Harding, S. P., Reeves, B. C., Muldrew, A., Parry, D. G., Rogers, C. A., Sahni, J. N., . . . Chakravarthy, U. (2013). The relationship between haemorrhage and OCT signs and the likelihood of neovascular amd being active during follow-up: Data from the IVAN study.. Invest Ophthalmol Vis Sci, 54, 3660.
2012
Advanced mathematical methods for medical image enhancement
Williams, B. M., Chen, K., Zheng, Y., & Harding, S. P. (2012). Advanced mathematical methods for medical image enhancement. University of Liverpool.
Prevalence of Raised Intracranial Pressure in Cerebral Malaria Detected by Optic Nerve Sheath Ultrasound
Beare, N. A. V., Glover, S. J., Lewallen, S., Taylor, T. E., Harding, S. P., & Molyneux, M. E. (2012). Prevalence of Raised Intracranial Pressure in Cerebral Malaria Detected by Optic Nerve Sheath Ultrasound. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 87(6), 985-988. doi:10.4269/ajtmh.2012.11-0459
Genome-wide association study of age-related macular degeneration identifies associated variants in the <i>TNXBFKBPLNOTCH4</i> region of chromosome 6p21.3
Cipriani, V., Leung, H. -T., Plagnol, V., Bunce, C., Khan, J. C., Shahid, H., . . . Yates, J. R. W. (2012). Genome-wide association study of age-related macular degeneration identifies associated variants in the <i>TNXBFKBPLNOTCH4</i> region of chromosome 6p21.3. HUMAN MOLECULAR GENETICS, 21(18), 4138-4150. doi:10.1093/hmg/dds225
Imaging of retinal whitening in retinal vein occlusion may shed light on malarial retinopathy
MacCormick, I. J. C., Beare, N. A. V., & Harding, S. P. (2012). Imaging of retinal whitening in retinal vein occlusion may shed light on malarial retinopathy. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 22(5), 868. doi:10.5301/ejo.5000134
A blind deconvolution model for images corrupted by gaussian blur
Williams, B. M., Chen, K., Zheng, Y., & Harding, S. P. (2012). A blind deconvolution model for images corrupted by gaussian blur. In Essex-Greenwich-Hertfordshire Workshop on Applied and Numerical Mathematics - Multiscale Problems. University of Greenwich.
Ranibizumab versus Bevacizumab to Treat Neovascular Age-related Macular Degeneration
Chakravarthy, U., Harding, S. P., Rogers, C. A., Downes, S. M., Lotery, A. J., Wordsworth, S., & Reeves, B. C. (2012). Ranibizumab versus Bevacizumab to Treat Neovascular Age-related Macular Degeneration. OPHTHALMOLOGY, 119(7). doi:10.1016/j.ophtha.2012.04.015
Advanced blur removal methods with applications to retinal imaging for ophthalmology
Williams, B. M., chen, K., zheng, Y., & Harding, S. (2012, July 9). Advanced blur removal methods with applications to retinal imaging for ophthalmology. In Medical Image Understanding and Analysis. Swansea University.
Mathematical methods for blind image deblurring
Williams, B. M., Chen, K., Zheng, Y., & Harding, S. P. (2012). Mathematical methods for blind image deblurring. In DITANET Symposium: Quantum Systems and Research(ers) at Accelerators.
Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy by Aspelund et al. (2011) Diabetologia 54:2525-2532
McGhee, S., Harding, S. P., & Wong, D. (2012). Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy by Aspelund et al. (2011) Diabetologia 54:2525-2532. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 250(4), 477-478. doi:10.1007/s00417-012-1939-2
Age-related macular degeneration: the importance of family history as a risk factor
Shahid, H., Khan, J. C., Cipriani, V., Sepp, T., Matharu, B. K., Bunce, C., . . . Yates, J. R. W. (2012). Age-related macular degeneration: the importance of family history as a risk factor. BRITISH JOURNAL OF OPHTHALMOLOGY, 96(3), 427-431. doi:10.1136/bjophthalmol-2011-300193
Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa
Glover, S. J., Burgess, P. I., Cohen, D. B., Harding, S. P., Hofland, H. W. C., Zijlstra, E. E., & Allain, T. J. (2012). Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa. BRITISH JOURNAL OF OPHTHALMOLOGY, 96(2), 156-161. doi:10.1136/bjo.2010.196071
Verteporfin photodynamic therapy for neovascular age-elated macular degeneration: cohort study for the UK
Reeves, B. C., Harding, S. P., Langham, J., Grieve, R., Tomlin, K., Walker, J., . . . Chakravarthy, U. (2012). Verteporfin photodynamic therapy for neovascular age-elated macular degeneration: cohort study for the UK. HEALTH TECHNOLOGY ASSESSMENT, 16(6), 1-+. doi:10.3310/hta16060
Verteporfin photodynamic therapy for neovascular age-related macular degeneration: cohort study for the UK.
Reeves, B. C., Harding, S. P., Langham, J., Grieve, R., Tomlin, K., Walker, J., . . . Chakravarthy, U. (2012). Verteporfin photodynamic therapy for neovascular age-related macular degeneration: cohort study for the UK.. Health technology assessment (Winchester, England), 16(6), i-200. doi:10.3310/hta16060
"Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications"
Simó, R., Hernández, C., Arce, R., Bandello, F., Burks, D., Cunha-Vaz, J., . . . Valverde, A. M. (2012). "Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications". British Journal of Ophthalmology, 96(10), 1285-1290.
Autofluorescence and reflectance imaging of macular laser scars.
Raj, A., Harding, S. P., & Sahni, J. N. (2012). Autofluorescence and reflectance imaging of macular laser scars.. Invest Ophthalmol Vis Sci, 53, 2688.
Automated segmentation of capillary non-perfusion (CNP) regions in fundus fluorescein angiograms (FA) using a texture-based approach.
Kwong, E. M. T., Zheng, Y., MacCormick, I. J., Beare, N. A. V., & Harding, S. P. (2012). Automated segmentation of capillary non-perfusion (CNP) regions in fundus fluorescein angiograms (FA) using a texture-based approach.. In Invest Ophthalmol Vis Sci Vol. 53 (pp. 4082).
Combined ranibizumab and photodynamic therapy for late-diagnosis polypoidal choroidal vasculopathy.
Figueredo, G. S., Stangos, A. A., Zheng, Y., Briggs, M. C., Harding, S. P., & Sahni, J. N. (2012). Combined ranibizumab and photodynamic therapy for late-diagnosis polypoidal choroidal vasculopathy.. In Invest Ophthalmol Vis Sci Vol. 53 (pp. 2060).
Living with AMD treatment - a qualitative study.
Knox, P. C., Thetford, C., Hodge, S., Harding, S. P., & Taylor, S. A. (2012). Living with AMD treatment - a qualitative study.. Invest Ophthalmol Vis Sci, 53, 5465.
Microvascular update: eyes
Harding, S. P. (2012). Microvascular update: eyes. In J. P. Vora (Ed.), Hot Topics in Diabetes (pp. 13-20). Surrey: Synergy.
Motion-free stereo fluorescein angiogram sequence.
Zheng, Y., Parry, D., Morphis, G., & Harding, S. P. (2012). Motion-free stereo fluorescein angiogram sequence.. In Invest Ophthalmol Vis Sci Vol. 53 (pp. 4103).
No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration
Cipriani, V., Matharu, B. K., Khan, J. C., Shahid, H., Hayward, C., Wright, A. F., . . . Yates, J. R. W. (2012). No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration. EUROPEAN JOURNAL OF HUMAN GENETICS, 20(1), 1-2. doi:10.1038/ejhg.2011.118
2011
Mathematical methods and algorithms for restoring retinal images with blur and blind blur
Williams, B. M., Chen, K., Zheng, Y., & Harding, S. P. (2011). Mathematical methods and algorithms for restoring retinal images with blur and blind blur. In Ophthalmology Image Analysis Workshop. University of Liverpool.
Early Multifocal Electroretinogram Findings during Intravitreal Ranibizumab Treatment for Neovascular Age-Related Macular Degeneration
Campa, C., Hagan, R., Sahni, J. N., Brown, M. C., Beare, N. A. V., Heimann, H., & Harding, S. P. (2011). Early Multifocal Electroretinogram Findings during Intravitreal Ranibizumab Treatment for Neovascular Age-Related Macular Degeneration. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52(6), 3446-3451. doi:10.1167/iovs.10-6588
Effectiveness of ranibizumab for neovascular age-related macular degeneration using clinician-determined retreatment strategy
Kumar, A., Sahni, J. N., Stangos, A. N., Campa, C., & Harding, S. P. (2011). Effectiveness of ranibizumab for neovascular age-related macular degeneration using clinician-determined retreatment strategy. BRITISH JOURNAL OF OPHTHALMOLOGY, 95(4), 530-533. doi:10.1136/bjo.2009.171868
Anti-VEGF Compounds in the Treatment of Neovascular Age Related Macular Degeneration
Campa, C., & Harding, S. P. (2011). Anti-VEGF Compounds in the Treatment of Neovascular Age Related Macular Degeneration. CURRENT DRUG TARGETS, 12(2), 173-181. doi:10.2174/138945011794182674
"Screening for Diabetic Retinopathy in Europe - Strategies for overcoming Hurdles to Progress. Report from National Representatives Meeting"
Harding, S. P., Broadbent, D. M., & Abba, K. (2011). "Screening for Diabetic Retinopathy in Europe - Strategies for overcoming Hurdles to Progress. Report from National Representatives Meeting". Retrieved from http://www.drscreening2005.org.uk/gdansk_2011.html
A supervised texture approach for segmentation of capillary nonperfusion regions in fundus fluorescein angiograms
Zheng, Y., Raj, A., Lu, H., Sahni, J. N., Beare, N. A. V., Broadbent, D., & Harding, S. P. (2011). A supervised texture approach for segmentation of capillary nonperfusion regions in fundus fluorescein angiograms. In ARVO/ISIE2011 Vol. ? (pp. ?).
Automated Assessment of Rentinal Image Quality using Support Vector Machine
Lu, H., Zheng, Y., Parry, D., Deane, J., & Harding, S. P. (2011). Automated Assessment of Rentinal Image Quality using Support Vector Machine. In Proc. of ARVO/ISIE Imaging Conference Vol. 1 (pp. 78).
Automated assessment of retinal image quality using support vector machine
Lu, H., Zheng, Y., Parry, D., Deane, J., & Harding, S. P. (2011). Automated assessment of retinal image quality using support vector machine. In ARVO/ISIE 2011 Vol. ? (pp. ?).
Choroidal thickness in diabetic eyes using SD-OCT enhanced depth imaging
Lu, H., Zheng, Y., Stangos, A. N., Broadbent, D. M., Sahni, J., & Harding, S. P. (2011). Choroidal thickness in diabetic eyes using SD-OCT enhanced depth imaging. In Inv Ophth Vis Sci Vol. 52 (pp. 1292).
Dexamethasone Intravitreal Implant in Patients with Macular Edema Related to Branch or Central Retinal Vein Occlusion Twelve-Month Study Results
Haller, J. A., Bandello, F., Belfort, R. J., Blumenkranz, M. S., Gillies, M., Heier, J., . . . Study Group, O. G. (2011). Dexamethasone Intravitreal Implant in Patients with Macular Edema Related to Branch or Central Retinal Vein Occlusion Twelve-Month Study Results. Ophthalmology.
Documentation of adverse events in non-commercial trials of intravitreal injection of anti-VEGF drugs to treat wet age-related macular degeneration (AMD)
Reeves, B. C., Underwood, W., Cappel-Porter, H., Baos, S., Rogers, C. A., Arnott, M., . . . Foss, A. E. (2011). Documentation of adverse events in non-commercial trials of intravitreal injection of anti-VEGF drugs to treat wet age-related macular degeneration (AMD). Trials, 12(Suppl 1), A13. doi:10.1186/1745-6215-12-s1-a13
Location and stability of fixation during anti-VEGF treatment for neovascular age-related macular degeneration
Campa, C., Zheng, Y., Hooley, W., Sahni, J. N., Beare, N. A., & Heimann, H. (2011). Location and stability of fixation during anti-VEGF treatment for neovascular age-related macular degeneration. In EURETINA Vol. ? (pp. ?).
PREVALENCE OF DIABETIC RETINOPATHY AND VISUAL IMPAIRMENT IN DIABETIC PATIENTS IN SUB-SAHARAN AFRICA
Harding, S. P., Glover, S. J., Burgess, P. I., Cohen, D. B., Hofland, H. W. C., Zijlstra, E. E., & Allain, T. J. (2011). PREVALENCE OF DIABETIC RETINOPATHY AND VISUAL IMPAIRMENT IN DIABETIC PATIENTS IN SUB-SAHARAN AFRICA. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 21(3), 347. Retrieved from https://www.webofscience.com/
SOMA: A Proposed Framework for Trend Mining in Large UK Diabetic Retinopathy Temporal Databases
Somaraki, V., Harding, S., Broadbent, D., & Coenen, F. (2011). SOMA: A Proposed Framework for Trend Mining in Large UK Diabetic Retinopathy Temporal Databases. In RESEARCH AND DEVELOPMENT IN INTELLIGENT SYSTEMS XXVII: INCORPORATING APPLICATIONS AND INNOVATIONS IN INTELLIGENT SYSTEMS XVIII (pp. 285-290). doi:10.1007/978-0-85729-130-1_22
SOMA: A proposed framework for trend mining in large UK diabetic retinopathy temporal databases
Somaraki, V., Harding, S., Broadbent, D., & Coenen, F. (2011). SOMA: A proposed framework for trend mining in large UK diabetic retinopathy temporal databases. In Res. and Dev. in Intelligent Syst. XXVII: Incorporating Applications and Innovations in Intel. Sys. XVIII - AI 2010, 30th SGAI Int. Conf. on Innovative Techniques and Applications of Artificial Intel. (pp. 285-290). doi:10.1007/978-0-85729-130-1_22
Spectral-domain OCT of eyes with chronic central serous retinopathy treated with photodynamic therapy
Morphis, G., Zheng, Y., Stangos, A., Beare, N., Harding, S., & Sahni, J. (2011). Spectral-domain OCT of eyes with chronic central serous retinopathy treated with photodynamic therapy. In AAO2011 Vol. ? (pp. ?).
Survival analysis of diabetic patients undergoing vitrectomy
Morphis, G. M., Sandigha, T. A., McKay, I. A., Broadbent, D. M., Harding, S. P., & Heimann, H. (2011). Survival analysis of diabetic patients undergoing vitrectomy. European Journal of Ophthalmology, 21(3), 346.
2010
Polypoidal Choroidal Vasculopathy Masquerading as Neovascular Age-Related Macular Degeneration Refractory to Ranibizumab
Stangos, A. N., Gandhi, J. S., Nair-Sahni, J., Heimann, H., Pournaras, C. J., & Harding, S. P. (2010). Polypoidal Choroidal Vasculopathy Masquerading as Neovascular Age-Related Macular Degeneration Refractory to Ranibizumab. AMERICAN JOURNAL OF OPHTHALMOLOGY, 150(5), 666-673. doi:10.1016/j.ajo.2010.05.035
Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study)
Massin, P., Bandello, F., Garweg, J. G., Hansen, L. L., Harding, S. P., Larsen, M., . . . Wolf, S. (2010). Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study). DIABETES CARE, 33(11), 2399-2405. doi:10.2337/dc10-0493
Finding Temporal Patterns in Noisy Longitudinal Data: A Study in Diabetic Retinopathy
Somaraki, V., Broadbent, D., Coenen, F., & Harding, S. (2010). Finding Temporal Patterns in Noisy Longitudinal Data: A Study in Diabetic Retinopathy. In ADVANCES IN DATA MINING: APPLICATIONS AND THEORETICAL ASPECTS Vol. 6171 (pp. 418-+). Retrieved from https://www.webofscience.com/
Automated Segmentation of Foveal Avascular Zone in Fundus Fluorescein Angiography
Zheng, Y., Gandhi, J. S., Stangos, A. N., Campa, C., Broadbent, D. M., & Harding, S. P. (2010). Automated Segmentation of Foveal Avascular Zone in Fundus Fluorescein Angiography. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(7), 3653-3659. doi:10.1167/iovs.09-4935
Automated Segmentation of Foveal Avascular Zone in Fundus Fluorescein Angiography
Zheng, Y., Gandhi, J. S., Stangos, A. N., Campa, C., Broadbent, D. M., & Harding, S. P. (2010). Automated Segmentation of Foveal Avascular Zone in Fundus Fluorescein Angiography. Investigative Opthalmology & Visual Science, 51(7), 3653. doi:10.1167/iovs.09-4935
Two-Year Visual Results for Older Asian Women Treated With Photodynamic Therapy or Bevacizumab for Myopic Choroidal Neovascularization
Campa, C., & Harding, S. P. (2010). Two-Year Visual Results for Older Asian Women Treated With Photodynamic Therapy or Bevacizumab for Myopic Choroidal Neovascularization. AMERICAN JOURNAL OF OPHTHALMOLOGY, 149(6), 1014-1015. doi:10.1016/j.ajo.2010.02.021
Automated segmentation of capillary non-perfusion from fundus fluorescein angiograms
Zheng, Y., Raj, A., Lu, H., Sahni, J., Beare, N., & Harding, S. (2010). Automated segmentation of capillary non-perfusion from fundus fluorescein angiograms. In Imaging in the eye V: Technologies and Clinical Applications Vol. ? (pp. ?).
Baseline clinical measures and early response predict success in verteporfin photodynamic therapy for neovascular age-related macular degeneration
Garcia-Finana, M., Murjaneh, S., Mahmood, S., & Harding, S. P. (2010). Baseline clinical measures and early response predict success in verteporfin photodynamic therapy for neovascular age-related macular degeneration. EYE, 24(7), 1213-1219. doi:10.1038/eye.2009.319
Bevacizumab for neovascular age related macular degeneration (ABC Trial): multicentre randomised double masked study.
Tufail, A., Patel, P. J., Egan, C., Hykin, P., da, C. L., Gregor, Z., . . . Trial Investigators, A. B. C. (2010). Bevacizumab for neovascular age related macular degeneration (ABC Trial): multicentre randomised double masked study.. British Medical Journal, 340, 2459.
Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study
Campa, C., Kearns, V., Sheridan, C., Williams, R., Grierson, I., & Harding, S. P. (2010). Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 51. Retrieved from https://www.webofscience.com/
Fast Interactive Segmentation of fluid spaces in fourier-domain OCT images of the retina
Zheng, Y., Campa, C., Stangos, A. N., Parry, D., Deane, J., & Sahni, J. N. (2010). Fast Interactive Segmentation of fluid spaces in fourier-domain OCT images of the retina. In ARVO/ISIE Vol. ? (pp. ?).
Fast automated segmentation of fluid spaces in fourier-domain OCT images of the retina
Zheng, Y., Campa, C., Stangos, A. N., Parry, D., Deane, J., & Harding, S. P. (2010). Fast automated segmentation of fluid spaces in fourier-domain OCT images of the retina. In Inv Ophth Vis Sci Vol. 51 (pp. 1784).
Incidence of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation
Campa, C., Harding, S. P., Pearce, I. A., Beare, N. A. V., Briggs, M. C., & Heimann, H. (2010). Incidence of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation. EYE, 24(10), 1585-1589. doi:10.1038/eye.2010.88
Neovascular age-related macular degeneration: decision making and optimal management
Harding, S. P. (2010). Neovascular age-related macular degeneration: decision making and optimal management. EYE, 24(3), 497-505. doi:10.1038/eye.2009.316
Optimisation of a fluorescein angiography protocol for improved clinical assessment of capillary perfusion in the diabetic macula
Gandhi, J. S., Campa, C., Zheng, Y., Sanusi, D., Broadbent, D. M., & Harding, S. P. (2010). Optimisation of a fluorescein angiography protocol for improved clinical assessment of capillary perfusion in the diabetic macula. In Inv Ophth Vis Sci Vol. 51 (pp. 4695).
The effects of hypoxia on the ERG in paediatric cerebral malaria
Lochhead, J., Movaffaghy, A., Falsini, B., Harding, S., Riva, C., & Molyneux, M. (2010). The effects of hypoxia on the ERG in paediatric cerebral malaria. EYE, 24(2), 259-264. doi:10.1038/eye.2009.162
Trend Mining in Logitudinal Diabetic Retinopathy Data
Somaraki, V., Broadbent, D., Coenen, F. P., & Harding, S. (2010). Trend Mining in Logitudinal Diabetic Retinopathy Data. In BCS SGAI conference on AI (pp. 285-290). UK: Springer.
2009
Observational prospective study of the effectiveness in routine clinical practice of verteporfin photodynamic therapy in patients with neovascular age-related macular degeneration
Murjaneh, S., Garcia-Finana, M., Mahmood, S., Lenfestey, P. M., Taylor, S. A., Pearce, I. A., . . . Harding, S. P. (2009). Observational prospective study of the effectiveness in routine clinical practice of verteporfin photodynamic therapy in patients with neovascular age-related macular degeneration. British Journal of Ophthalmology, 93(4), 468-473. doi:10.1136/bjo.2008.141366
Observational prospective study of the effectiveness in routine clinical practice of verteporfin photodynamic therapy in patients with neovascular age-related macular degeneration
Murjaneh, S., Garcia-Finana, M., Mahmood, S., Lenfestey, P. M., Taylor, S. A., Pearce, I. A., . . . Harding, S. P. (2009). Observational prospective study of the effectiveness in routine clinical practice of verteporfin photodynamic therapy in patients with neovascular age-related macular degeneration. BRITISH JOURNAL OF OPHTHALMOLOGY, 93(4), 468-473. doi:10.1136/bjo.2008.141366
Perfusion Abnormalities in Children with Cerebral Malaria and Malarial Retinopathy
Beare, N. A. V., Harding, S. P., Taylor, T. E., Lewallen, S., & Molyneux, M. E. (2009). Perfusion Abnormalities in Children with Cerebral Malaria and Malarial Retinopathy. JOURNAL OF INFECTIOUS DISEASES, 199(2), 263-271. doi:10.1086/595735
Automated segmentation of foveal avascular zone in fluorescein angiography in a clinical setting.
Zheng, Y., Sharp, J., Campa, C., Sahni, J. N., Broadbent, D. M., & Harding, S. P. (2009). Automated segmentation of foveal avascular zone in fluorescein angiography in a clinical setting.. In Investigative Ophthalmology and Vision Science Vol. 50 (pp. 330).
Early response of retinal angiomatous proliferation treated with intravitreal pegaptanib: a retrospective review
Mahmood, S., Kumar, N., Lenfestey, P. M., Murjaneh, S., Heimann, H., & Harding, S. P. (2009). Early response of retinal angiomatous proliferation treated with intravitreal pegaptanib: a retrospective review. EYE, 23(3), 530-535. doi:10.1038/eye.2008.101
New classification of acute papilledema in children with severe malaria.
Smith, A., Beare, N. A. V., Musumba, C. O., Lochhead, J., Newton, C. R. J. C., & Harding, S. P. (2009). New classification of acute papilledema in children with severe malaria.. Journal of pediatric neurology : JPN, 7(4), 381-388. doi:10.3233/jpn-2009-0317
New classification of acute papilloedema based on prognostic value of optic disc features in children with severe malaria.
Smith, A., Beare, N. A. V., Musumba, C., Lochhead, J., Newton, C. R. J. C., & Harding, S. P. (2009). New classification of acute papilloedema based on prognostic value of optic disc features in children with severe malaria.. Journal of Paediatric Neurology, 7(4), 381-388.
Retinal angiographic changes in paediatric cerebral malaria
Glover, S. J., Harding, S. P., Taylor, E., Beare, N. A. V., & Molyneux, M. E. (2009). Retinal angiographic changes in paediatric cerebral malaria. American Journal of Tropical Medicine and Hygiene, 81, 508.
Risk of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation.
Campa, C., Beare, N. A. V., Briggs, M. C., Lenfestey, P. M., Pearce, I. A., Sahni, J. N., . . . Heimann, H. (2009). Risk of neovascularization in the fellow eye of patients with unilateral retinal angiomatous proliferation.. Investigative Ophthalmology and Vision Science, 50, 270.
Segmentation of foveal avascular zone from fluorescein angiography using a level set method.
Zheng, Y., Sharp, J., Campa, C., Sahni, J. N., Broadbent, D. M., & Harding, S. P. (2009). Segmentation of foveal avascular zone from fluorescein angiography using a level set method.. In Eur J Ophthalmol Vol. 19 (pp. 508).
Verteporfin Photodynamic Therapy Cohort Study <i>Report 2</i>: <i>Clinical Measures of Vision and Health</i>-<i>Related Quality of Life</i>
Reeves, B. C., Langham, J., Walker, J., Grieve, R., Chakravarthy, U., Tomlin, K., . . . Harding, S. P. (2009). Verteporfin Photodynamic Therapy Cohort Study <i>Report 2</i>: <i>Clinical Measures of Vision and Health</i>-<i>Related Quality of Life</i>. OPHTHALMOLOGY, 116(12), 2463-2470. doi:10.1016/j.ophtha.2009.10.031
Verteporfin Photodynamic Therapy Cohort Study <i>Report 3</i>: <i>Cost Effectiveness and Lessons for Future Evaluations</i>
Grieve, R., Guerriero, C., Walker, J., Tomlin, K., Langham, J., Harding, S., . . . Reeves, B. C. (2009). Verteporfin Photodynamic Therapy Cohort Study <i>Report 3</i>: <i>Cost Effectiveness and Lessons for Future Evaluations</i>. OPHTHALMOLOGY, 116(12), 2471-2477. doi:10.1016/j.ophtha.2009.10.023
Verteporfin photodynamic therapy cohort study: report 1: effectiveness and factors influencing outcomes.
Harding, S. P., Tomlin, K., Reeves, B. C., Langham, J., Walker, J., Carpenter, J., . . . Verteporfin Photodynamic Therapy Cohort Study Group. (2009). Verteporfin photodynamic therapy cohort study: report 1: effectiveness and factors influencing outcomes.. Ophthalmology, 116(12), e1-e8. doi:10.1016/j.ophtha.2009.10.022
Verteporfin therapy in occult with no classic CNV due to AMD: results of the Photodynamic Therapy in Occult-Only Lesions study
Soubrane, G., Harding, S. P., Wolf, S., & Weichselberger, A. (2009). Verteporfin therapy in occult with no classic CNV due to AMD: results of the Photodynamic Therapy in Occult-Only Lesions study. EYE, 23(4), 791-800. doi:10.1038/eye.2008.158
2008
Uveitis triggered by acute onset gastroenteritis
Cazabon, S., Quah, S. A., Pearce, I. A., & Harding, S. P. (2008). Uveitis triggered by acute onset gastroenteritis. International Journal of Clinical Practice, 62(12), 1957-1958. doi:10.1111/j.1742-1241.2006.01108.x
Detection of raised intracranial pressure by ultrasound measurement of optic nerve sheath diameter in African children
Beare, N. A. V., Kampondeni, S., Glover, S. J., Molyneux, E., Taylor, T. E., Harding, S. P., & Molyneux, M. E. (2008). Detection of raised intracranial pressure by ultrasound measurement of optic nerve sheath diameter in African children. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 13(11), 1400-1404. doi:10.1111/j.1365-3156.2008.02153.x
Using malarial retinopathy to improve the classification of children with cerebral malaria
Lewallen, S., Bronzan, R. N., Beare, N. A., Harding, S. P., Molyneux, M. E., & Taylor, T. E. (2008). Using malarial retinopathy to improve the classification of children with cerebral malaria. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 102(11), 1089-1094. doi:10.1016/j.trstmh.2008.06.014
Enhancement of blood vessels in digital fundus photographs via the application of multiscale line operators
Farnell, D. J. J., Hatfield, F. N., Knox, P., Reakes, M., Spencer, S., Parry, D., & Harding, S. P. (2008). Enhancement of blood vessels in digital fundus photographs via the application of multiscale line operators. JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS, 345(7), 748-765. doi:10.1016/j.jfranklin.2008.04.009
Lessons learned in setting up a reading centre network for high volume grading in Europe
PATTON, W. P., MULDREW, K. A., HARDING, S. P., CHAKRAVARTHY, U., & PETO, T. (2008). Lessons learned in setting up a reading centre network for high volume grading in Europe. Acta Ophthalmologica, 86(s243), 0. doi:10.1111/j.1755-3768.2008.6316.x
Preliminary reading centre concordance in OCT grading in the UK IVAN Study
PATTON, W. P., MULDREW, K. A., PETO, T., LENFESTY, P., HARDING, S. P., & CHAKRAVARTHY, U. (2008). Preliminary reading centre concordance in OCT grading in the UK IVAN Study. Acta Ophthalmologica, 86(s243), 0. doi:10.1111/j.1755-3768.2008.629.x
A preliminary model-based assessment of the cost-utility of a screening programme for early age-related macular degeneration.
Karnon, J., Czoski-Murray, C., Smith, K., Brand, C., Chakravarthy, U., Davis, S., . . . Yang, Y. C. (2008). A preliminary model-based assessment of the cost-utility of a screening programme for early age-related macular degeneration.. Health technology assessment (Winchester, England), 12(27), iii-124. doi:10.3310/hta12270
A preliminary model-based assessment of the cost-utility of a screening programme for early age-related macular degeneration
Karnon, J., Czoski-Murray, C., Smith, K., Brand, C., Chakravarthy, U., Davis, S., . . . Yang, Y. C. (2008). A preliminary model-based assessment of the cost-utility of a screening programme for early age-related macular degeneration. HEALTH TECHNOLOGY ASSESSMENT, 12(27), 2-+. Retrieved from https://www.webofscience.com/
Concordance of fluorescein angiography grading at the Network of Ophthalmic Reading Centres in the United Kingdom.
Peto, T., Patton, W. P., Muldrew, A. K., Lenfestey, P. M., Reeves, B., Harding, S. P., . . . theVPDT Cohort Study Team. (2008). Concordance of fluorescein angiography grading at the Network of Ophthalmic Reading Centres in the United Kingdom.. Investigative Ophthalmology and Vision Science, 49, 2248.
Delayed visual evoked potentials in children with Plasmodium falciparum malaria and reduced consciousness
Southern, C. L., Beare, N. A. V., Falsini, B., Lochhead, J., Molyneux, M. E., Taylor, T. E., & Harding, S. P. (2008). Delayed visual evoked potentials in children with Plasmodium falciparum malaria and reduced consciousness. Journal of Pediatric Neurology, 6(1), 17-24.
Fundus fluorescein angiography in paediatric cerebral malaria.
Glover, S. J., Harding, S. P., Molyneux, M. E., Lewallen, S., Taylor, T. E., & Beare, N. A. V. (2008). Fundus fluorescein angiography in paediatric cerebral malaria.. Investigative Ophthalmology and Vision Science, 49, 5047.
Lesion components in eyes of patients with neovascular AMD without active CNV: Analysis of a subset of angiograms graded in the VPDT Cohort Study for the UK.
Patton, W. P., Muldrew, K. A., Peto, T., Harding, S. P., Lenfestey, P. M., & Chakravarthy, U. (2008). Lesion components in eyes of patients with neovascular AMD without active CNV: Analysis of a subset of angiograms graded in the VPDT Cohort Study for the UK.. Investigative Ophthalmology and Vision Science, 49, 578.
Multifocal electroretinography as a predictor of maintenance of vision after photodynamic therapy for neovascular age-related macular degeneration
Mackay, A. M., Brown, M. C., Grierson, I., & Harding, S. P. (2008). Multifocal electroretinography as a predictor of maintenance of vision after photodynamic therapy for neovascular age-related macular degeneration. DOCUMENTA OPHTHALMOLOGICA, 116(1), 13-18. doi:10.1007/s10633-007-9071-z
New drugs for diabetic retinopathy
Harding, S. P. (2008). New drugs for diabetic retinopathy. In J. Vora (Ed.), Diabetes Hot Topics (pp. 45-50). Richmond, Surrey: Synergy.
Prevalence of vascular risk factors in patients attending a diabetic eye screening programme: primary versus secondary care.
Collaer, N., Fisher, A. C., Harding, S. P., Vora, J. P., & Broadbent, D. M. (2008). Prevalence of vascular risk factors in patients attending a diabetic eye screening programme: primary versus secondary care.. Eur J Ophthalmol, 18, 496.
Prevalence of vascular risk factors in sight threatening diabetic retinopathy identified in a retinopathy screening programme.
Collaer, N., Fisher, A. C., Harding, S. P., Vora, J. P., & Broadbent, D. M. (2008). Prevalence of vascular risk factors in sight threatening diabetic retinopathy identified in a retinopathy screening programme.. Eur J Ophthalmol, 18, 497.
Temporal relationship between different measures ovisual function in patients with neovascular macular degeneration treated with photodynamic therapy.
Mandal, K., Fisher, A. C., Tompkin, V. J., Tompkin, A. P., Murjaneh, S., Collaer, N., . . . Harding, S. P. (2008). Temporal relationship between different measures ovisual function in patients with neovascular macular degeneration treated with photodynamic therapy.. Investigative Ophthalmology and Vision Science, 49, 600.
The introduction of verteporfin photodynamic therapy in the UK: PDT users group (PDTUG) surveillance programme report 1
Ghanchi, F. D., Fullarton, J., Blake, J., & Harding, S. P. (2008). The introduction of verteporfin photodynamic therapy in the UK: PDT users group (PDTUG) surveillance programme report 1. EYE, 22(5), 671-677. doi:10.1038/sj.eye.6702713
The relationship between visual acuity and health-related quality of life. Report from the UK VPDT Cohort Study.
Harding, S. P., Reeves, B., Walker, J., Langham, J., Grieve, R., Tomlin, K., . . . the VPDT Cohort Study Group.. (2008). The relationship between visual acuity and health-related quality of life. Report from the UK VPDT Cohort Study.. Investigative Ophthalmology and Vision Science, 49, 3754.
Uveitis triggered by acute onset gastroenteritis
Cazabon, S., Quah, S. A., Pearce, I. A., & Harding, S. P. (2008). Uveitis triggered by acute onset gastroenteritis. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 62(12). doi:10.1111/j.1742-1241.2006.01108.x
Variation in measures of visual function in patients with neovascular macular degeneration.
Tompkin, V. J., Mandal, K., Fisher, A. C., Tompkin, A. P., Murjaneh, S., Collaer, N., . . . Harding, S. P. (2008). Variation in measures of visual function in patients with neovascular macular degeneration.. Investigative Ophthalmology and Vision Science, 49, 601.
2007
Deficits in the electroretinogram in neovascular age-related macular degeneration and changes during photodynamic therapy
Mackay, A. M., Brown, M. C., Hagan, R. P., Fisher, A. C., Grierson, I., & Harding, S. P. (2007). Deficits in the electroretinogram in neovascular age-related macular degeneration and changes during photodynamic therapy. DOCUMENTA OPHTHALMOLOGICA, 115(2), 69-76. doi:10.1007/s10633-007-9056-y
Training improves the identification of Retinal Angiomatous Proliferation in the UK network of ophthalmic reading centres
PATTON, W. P., PETO, T., MULDREW, K. A., REEVES, B., LENFESTY, P., HARDING, S. P., . . . CHAKRAVARTHY, U. (2007). Training improves the identification of Retinal Angiomatous Proliferation in the UK network of ophthalmic reading centres. Acta Ophthalmologica Scandinavica, 85(s240), 0. doi:10.1111/j.1600-0420.2007.01062_3217.x
Role of folate deficiency in the pathogenesis of retinal and cerebral hemorrhages in cerebral malaria
Beare, N. A. V., Taylor, T. E., Harding, S. P., Lewallen, S., & Molyneux, M. E. (2007). Role of folate deficiency in the pathogenesis of retinal and cerebral hemorrhages in cerebral malaria. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 76(5), 793-794. doi:10.4269/ajtmh.2007.76.793
Bevacizumab: a word of caution
Kumar, N., Sebastian, R., Harding, S., & Pearce, I. (2007). Bevacizumab: a word of caution. CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, 42(5), 760-761. doi:10.3129/i07-139
Optical coherence tomography analysis of bilateral end-stage choroidal neovascularization where one eye is treated with photodynamic therapy
Sahni, J., Stanga, P., Wong, D., Lenfestey, P., Kent, D., & Harding, S. (2007). Optical coherence tomography analysis of bilateral end-stage choroidal neovascularization where one eye is treated with photodynamic therapy. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 35(1), 13-17. doi:10.1111/j.1442-9071.2006.01385.x
Photodynamic therapy for angioid streaks
Browning, A. C., Amoaku, W. M., Chung, A. K., Ghanchi, F., Harding, S. P., Musadiq, M., . . . Talks, S. J. (2007). Photodynamic therapy for angioid streaks. OPHTHALMOLOGY, 114(8), 1592-1593. doi:10.1016/j.ophtha.2007.03.057
2006
Changes in optic nerve head blood flow in children with cerebral malaria and acute papilloedema
Beare, N. A. V., Riva, C. E., Taylor, T. E., Molyneux, M. E., Kayira, K., White, V. A., . . . Harding, S. P. (2006). Changes in optic nerve head blood flow in children with cerebral malaria and acute papilloedema. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 77(11), 1288-1290. doi:10.1136/jnnp.2005.083956
Optimizing the use of tumor necrosis factoralpha inhibitors in refractory uveitis.
Sebastian, R. T., Harding, S. P., Bucknall, R. C., & Pearce, I. A. (2006). Optimizing the use of tumor necrosis factoralpha inhibitors in refractory uveitis.. Archives of ophthalmology (Chicago, Ill. : 1960), 124(10), 1505. doi:10.1001/archopht.124.10.1505-a
Mycophenolate mofetil as an immunosuppressive agent in refractory inflammatory eye disease
Choudhary, A., Harding, S. P., Bucknall, R. C., & Pearce, I. A. (2006). Mycophenolate mofetil as an immunosuppressive agent in refractory inflammatory eye disease. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 22(3), 168-175. doi:10.1089/jop.2006.22.168
Classifying and grading retinal signs in severe malaria
Harding, S. P., Lewallen, S., Beare, N. A. V., Smith, A., Taylor, T. E., & Molyneux, M. E. (2006). Classifying and grading retinal signs in severe malaria. TROPICAL DOCTOR, 36, 1-13. doi:10.1258/004947506776315781
Classifying and grading retinal signs in severe malaria.
Harding, S. P., Lewallen, S., Beare, N. A. V., Smith, A., Taylor, T. E., & Molyneux, M. E. (2006). Classifying and grading retinal signs in severe malaria.. Tropical doctor, 36 Suppl 1, 1-13. doi:10.1258/004947506776315781
Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers
Sepp, T., Khan, J. C., Thurlby, D. A., Shahid, H., Clayton, D. G., Moore, A. T., . . . Yates, J. R. W. (2006). Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 47(2), 536-540. doi:10.1167/iovs.05-1143
Characteristics of Blood-Vessel Tracings from Fundus Photographs in Diabetic Retinopathy Screening
Farnell, D. J. J., Spencer, S., Parry, D., Reakes, M., Hatfield, F. N., Knox, P. C., & Harding, S. P. (2006). Characteristics of Blood-Vessel Tracings from Fundus Photographs in Diabetic Retinopathy Screening. Journal of Medical Screening, ?(?).
Diabetic Retinopathy
Harding, S. P. (2006). Diabetic Retinopathy. In D. Tovey (Ed.), Clinical Evidence Concise (pp. 158-159). London: BMJ Publishing Group.
Diabetic retinopathy.
Harding, S. (2006). Diabetic retinopathy.. Clinical evidence, (15), 900-907.
Malarial retinopathy: A newly established diagnostic sign in severe malaria
Beare, N. A. V., Taylor, T. E., Harding, S. P., Lewallen, S., & Molyneux, M. E. (2006). Malarial retinopathy: A newly established diagnostic sign in severe malaria. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 75(5), 790-797. doi:10.4269/ajtmh.2006.75.790
Screening for Diabetic Retinopathy in Europe
Harding, S. P. (Ed.) (2006). Screening for Diabetic Retinopathy in Europe. In Screening for Diabetic Retinopathy in Europe (pp. 1-65). Liverpool: Liverpool. Retrieved from http://www.drscreening2006.org.uk/
2005
Optical coherence tomography of the vitreomacular interface in photodynamic therapy
Witkin, A. J., & Duker, J. S. (2005). Optical coherence tomography of the vitreomacular interface in photodynamic therapy. BRITISH JOURNAL OF OPHTHALMOLOGY, 89(7), 929. doi:10.1136/bjo.2005.071100
Optical coherence tomography in photodynamic therapy for subfoveal choroidal neovascularisation secondary to age related macular degeneration: a cross sectional study
Sahni, J., Stanga, P., Wong, D., & Harding, S. (2005). Optical coherence tomography in photodynamic therapy for subfoveal choroidal neovascularisation secondary to age related macular degeneration: a cross sectional study. BRITISH JOURNAL OF OPHTHALMOLOGY, 89(3), 316-320. doi:10.1136/bjo.2004.043364
Diabetic Retinopathy
Harding, S. P. (2005). Diabetic Retinopathy. In D. Tovey (Ed.), Clinical Evidence Concise (pp. 201-202). London: BMJ Publishing Group.
The impact of national diabetic retinopathy screening on ophthalmology: the need for urgent planning
Harding, S., Garvican, L., & Talbot, J. (2005). The impact of national diabetic retinopathy screening on ophthalmology: the need for urgent planning. EYE, 19(9), 1009-1011. doi:10.1038/sj.eye.6701751
Verteporfin photodynamic therapy of choroidal neovascularization in angioid streaks - One-year results of a prospective case series
Browning, A. C., Chung, A. K. K., Ghanchi, F., Harding, S. P., Musadiq, M., Talks, S. J., . . . Amoaku, W. M. (2005). Verteporfin photodynamic therapy of choroidal neovascularization in angioid streaks - One-year results of a prospective case series. OPHTHALMOLOGY, 112(7), 1227-1231. doi:10.1016/j.ophtha.2005.02.011
2004
Prognostic significance and course of retinopathy in children with severe malaria
Beare, N. A., Southern, C., Chalira, C., Taylor, T. E., Molyneux, M. E., & Harding, S. P. (2004). Prognostic significance and course of retinopathy in children with severe malaria. ARCHIVES OF OPHTHALMOLOGY, 122(8), 1141-1147. doi:10.1001/archopht.122.8.1141
The English national risk-reduction programme for preservation of sight in diabetes
Gillibrand, W., Broadbent, D., Harding, S., & Vora, J. (2004). The English national risk-reduction programme for preservation of sight in diabetes. MOLECULAR AND CELLULAR BIOCHEMISTRY, 261(1-2), 183-185. doi:10.1023/B:MCBI.0000028754.70862.13
Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3.
Arnold, J. J., Blinder, K. J., Bressler, N. M., Bressler, S. B., Burdan, A., Haynes, L., . . . Verteporfin in Photodynamic Therapy Study Group. (2004). Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3.. American journal of ophthalmology, 137(4), 683-696. doi:10.1016/j.ajo.2003.11.059
Patchy ischemic retinal whitening - Reply
Beare, N., Harding, S., & Lewallen, S. (2004). Patchy ischemic retinal whitening - Reply. OPHTHALMOLOGY, 111(3), 607. doi:10.1016/j.ophtha.2003.12.046
Visual outcomes in children in Malawi following retinopathy of severe malaria
Beare, N. A. V., Southern, C., Kayira, K., Taylor, T. E., & Harding, S. P. (2004). Visual outcomes in children in Malawi following retinopathy of severe malaria. BRITISH JOURNAL OF OPHTHALMOLOGY, 88(3), 321-324. doi:10.1136/bjo.2003.025924
'Natural History of Minimally Classic Subfoveal Choroidal Neovascular Lesions in the Treatment of Age-related Macular Degeneration with Photodynamic Therpay (TAP) Investigation. TAP Report No. 6'
Group, T. S. (2004). 'Natural History of Minimally Classic Subfoveal Choroidal Neovascular Lesions in the Treatment of Age-related Macular Degeneration with Photodynamic Therpay (TAP) Investigation. TAP Report No. 6'. Archives of Ophthalmology, 122(3), 325-329.
'Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) and Verteporfin In Photodynamic Therapy (VIP) Study Groups. Verteporfin therapy of subfoveal choroidal neovascularization in age related macular degeneration: meta-analysis of 2-year safety results in three randomized clinical trials: Treatment of Age-related Macular Degeneration with Photodynamic Therapy and Verteporfin in Photodynamic Therapy Study Report No. 4'
TAP., & VIP Study Group. (2004). 'Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) and Verteporfin In Photodynamic Therapy (VIP) Study Groups. Verteporfin therapy of subfoveal choroidal neovascularization in age related macular degeneration: meta-analysis of 2-year safety results in three randomized clinical trials: Treatment of Age-related Macular Degeneration with Photodynamic Therapy and Verteporfin in Photodynamic Therapy Study Report No. 4'. Retina, 24, 1-12.
Automatic Detection of Retinal Blood Vessels
Hatfield, F. N., Farnell, D. J. J., Knox, P. C., & Harding, S. (2004). Automatic Detection of Retinal Blood Vessels. In IPEM-Institute of Physics and Engineering in Medicine Annual Scientific Conference Vol. 1 (pp. 111-112). York: IPEM.
Diabetic Retinopathy
Harding, S. P. (2004). Diabetic Retinopathy. In F. Godlee (Ed.), Clinical Evidence - Concise (pp. 159-160). London: BMJ Publishing.
Diabetic retinopathy.
Harding, S. (2004). Diabetic retinopathy.. Clinical evidence, (12), 939-950.
Diabetic retinopathy.
Harding, S. (2004). Diabetic retinopathy.. Clinical evidence, (11), 848-859.
Outcomes in verteporfin photodynamic therapy for choroidal neovascularisation - 'beyond the TAP study'
Barnes, R. M., Gee, L., Taylor, S., Briggs, M. C., & Harding, S. P. (2004). Outcomes in verteporfin photodynamic therapy for choroidal neovascularisation - 'beyond the TAP study'. EYE, 18(8), 809-813. doi:10.1038/sj.eye.6701329
Patchy ischemic retinal whitening
Browning, D. J. (2004). Patchy ischemic retinal whitening. OPHTHALMOLOGY, 111(3), 606-607. doi:10.1016/j.ophtha.2003.12.033
2003
Grading and disease management in national screening for diabetic retinopathy in England and Wales
Harding, S., Greenwood, R., Aldington, S., Gibson, J., Owens, D., Taylor, R., . . . Leese, G. (2003). Grading and disease management in national screening for diabetic retinopathy in England and Wales. DIABETIC MEDICINE, 20(12), 965-971. doi:10.1111/j.1464-5491.2003.01077.x
Effect of lesion size, visual acuity, and lesion composition on visual acuity change with and without verteporfin therapy for choroidal neovascularization secondary to age-related macular degeneration: TAP and VIP report no. 1.
Blinder, K. J., Bradley, S., Bressler, N. M., Bressler, S. B., Donati, G., Hao, Y., . . . Verteporfin in Photodynamic Therapy study group. (2003). Effect of lesion size, visual acuity, and lesion composition on visual acuity change with and without verteporfin therapy for choroidal neovascularization secondary to age-related macular degeneration: TAP and VIP report no. 1.. American journal of ophthalmology, 136(3), 407-418. doi:10.1016/s0002-9394(03)00223-x
Incidence of sight-threatening retinopathy in Type 1 diabetes in a systematic screening programme
Younis, N., Broadbent, D. M., Harding, S. P., & Vora, J. P. (2003). Incidence of sight-threatening retinopathy in Type 1 diabetes in a systematic screening programme. DIABETIC MEDICINE, 20(9), 758-765. doi:10.1046/j.1464-5491.2003.01035.x
Extracts from "concise clinical evidence" - Diabetic retinopathy
Harding, S. (2003). Extracts from "concise clinical evidence" - Diabetic retinopathy. BRITISH MEDICAL JOURNAL, 326(7397), 1023-1024. doi:10.1136/bmj.326.7397.1023
The Effect of Quinine on the Electroretinograms of Children with Pediatric Cerebral Malaria
Lochhead, J., Movaffaghy, A., Falsini, B., Winstanley, P. A., Mberu, E. K., Riva, C. E., . . . Harding, S. P. (2003). The Effect of Quinine on the Electroretinograms of Children with Pediatric Cerebral Malaria. The Journal of Infectious Diseases, 187(8), 1342-1345. doi:10.1086/374058
The effect of quinine on the electroretinograms of children with pediatric cerebral malaria
Lochhead, J., Movaffaghy, A., Falsini, B., Winstanley, P. A., Mberu, E. K., Riva, C. E., . . . Harding, S. P. (2003). The effect of quinine on the electroretinograms of children with pediatric cerebral malaria. JOURNAL OF INFECTIOUS DISEASES, 187(8), 1342-1345. doi:10.1086/374058
Retinal changes in adults with cerebral malaria
Beare, N. A. V., Lewis, D. K., Kublin, J. G., Harding, S. P., Zijlstra, E. E., & Molyneux, M. E. (2003). Retinal changes in adults with cerebral malaria. ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 97(3), 313-315. doi:10.1179/000349803235001859
Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial--VIP report no. 3.
Blinder, K. J., Blumenkranz, M. S., Bressler, N. M., Bressler, S. B., Donato, G., Lewis, H., . . . Williams, G. A. (2003). Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial--VIP report no. 3.. Ophthalmology, 110(4), 667-673. doi:10.1016/s0161-6420(02)01998-x
Severe interferon associated retinopathy
Tu, K. L., Bowyer, J., Schofield, K., & Harding, S. (2003). Severe interferon associated retinopathy. BRITISH JOURNAL OF OPHTHALMOLOGY, 87(2), 247-248. doi:10.1136/bjo.87.2.247
Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study
Younis, N., Broadbent, D. M., Vora, J. P., & Harding, S. P. (2003). Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study. LANCET, 361(9353), 195-200. doi:10.1016/S0140-6736(03)12267-2
Ambulatory photographic screening for diabetic retinopathy in nursing homes
Anderson, S., Broadbent, D. M., Swain, J. Y. S., Vora, J. P., & Harding, S. P. (2003). Ambulatory photographic screening for diabetic retinopathy in nursing homes. EYE, 17(6), 711-716. doi:10.1038/sj.eye.6700487
Diabetic Retinopathy
Harding, S. P. (2003). Diabetic Retinopathy. In F. Godlee (Ed.), Clinical Evidence - Concise (pp. 142-143). London: BMJ Publishing.
Diabetic retinopathy.
Harding, S. (2003). Diabetic retinopathy.. Clinical evidence, (9), 718-728.
Treatment of Age-Related Macular Degeneration With Photodynamic Therapy (TAP) and Verteporfin in Photodynamic Therapy (VIP) Study Groups. Photodynamic Therapy of Subfoveal Choroidal Neovascularization With Verteporfin - Fluorescein Angiographic Guidelines for Evaluation and Treatment¿TAP and VIP Report No. 2.
TAP., & VIP study group. (2003). Treatment of Age-Related Macular Degeneration With Photodynamic Therapy (TAP) and Verteporfin in Photodynamic Therapy (VIP) Study Groups. Photodynamic Therapy of Subfoveal Choroidal Neovascularization With Verteporfin - Fluorescein Angiographic Guidelines for Evaluation and Treatment¿TAP and VIP Report No. 2.. Archives of Ophthalmology, 121, 1253-1268.
Treatment of Diabetic Retinopathy
Harding, S. P. (2003). Treatment of Diabetic Retinopathy. British Medical Journa;, 326(7397), 1023-1025.
Verteporfin photodynamic therapy in the UK: implications of the NICE appraisal
Harding, S. (2003). Verteporfin photodynamic therapy in the UK: implications of the NICE appraisal. EYE, 17(2), 119-122. doi:10.1038/sj.eye.6700469
2002
Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3.
Bressler, N. M., Arnold, J., Benchaboune, M., Blumenkranz, M. S., Fish, G. E., Gragoudas, E. S., . . . Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group. (2002). Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3.. Archives of ophthalmology (Chicago, Ill. : 1960), 120(11), 1443-1454. doi:10.1001/archopht.120.11.1443
Current status of screening for diabetic retinopathy in the UK
Younis, N., Broadbent, D. M., James, M., Harding, S. P., & Vora, J. P. (2002). Current status of screening for diabetic retinopathy in the UK. DIABETIC MEDICINE, 19, 44-49. doi:10.1046/j.1464-5491.19.s4.9.x
Inter-observer concordance in grading retinopathy in cerebral malaria
Beare, N. A., Southern, C., Lochhead, J., Molyneux, M. E., Lewallen, S., & Harding, S. P. (2002). Inter-observer concordance in grading retinopathy in cerebral malaria. ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 96(1), 105-108. doi:10.1179/000349802125000565
Diabetic retinopathy.
Harding, S. (2002). Diabetic retinopathy.. In Unknown Book (pp. 580-588).
Feasibility of LDF measurements of optic nerve head blood flow in children with cerebral malaria
Movaffaghy, A., Lochhead, J., Riva, C. E., Harding, S. P., Petrig, B. L., Molyneux, M. E., & Taylor, T. E. (2002). Feasibility of LDF measurements of optic nerve head blood flow in children with cerebral malaria. MICROVASCULAR RESEARCH, 64(2), 247-253. doi:10.1006/mvre.2002.2424
Prevalence of diabetic eye disease in patients entering a systematic primary care-based eye screening programme
Younis, N., Broadbent, D. M., Harding, S. P., & Vora, J. P. (2002). Prevalence of diabetic eye disease in patients entering a systematic primary care-based eye screening programme. DIABETIC MEDICINE, 19(12), 1014-1021. doi:10.1046/j.1464-5491.2002.00854.x
Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of 2 randomized clinical trials¿TAP Report No. 5
TAP study group. (2002). Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of 2 randomized clinical trials¿TAP Report No. 5. Archives of Ophthalmology, 120, 1307-1314.
2001
Macular degeneration treatment at Clatterbridge Centre for Oncology: Treatment and preliminary results
Kacperek, A., Briggs, M., Sheen, M. A., Damato, B. E., Errington, R. D., & Harding, S. (2001). Macular degeneration treatment at Clatterbridge Centre for Oncology: Treatment and preliminary results. PHYSICA MEDICA, 17, 7-9. Retrieved from https://www.webofscience.com/
Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin - 1-year results of a randomized clinical trial - VIP report no. 1
Arnold, J., Kilmartin, D., Olson, J., Neville, S., Robinson, K., Laird, A., . . . Verteporfin Photodynamic Therapy. (2001). Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin - 1-year results of a randomized clinical trial - VIP report no. 1. Ophthalmology: Journal of The American Academy of Ophthalmology, 108(5), 841-852.
Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization--verteporfin in photodynamic therapy report 2.
Verteporfin In Photodynamic Therapy Study Group. (2001). Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization--verteporfin in photodynamic therapy report 2.. American journal of ophthalmology, 131(5), 541-560. doi:10.1016/s0002-9394(01)00967-9
Photodynamic therapy in the treatment of subfoveal choroidal neovascularisation
Harding, S. (2001). Photodynamic therapy in the treatment of subfoveal choroidal neovascularisation. EYE, 15, 407-412. doi:10.1038/eye.2001.145
Photodynamic therapy of subfoveal choroidal neovascularisation in age-related macular degeneration with verteporphin. Two-year results of 2 randomised clinical trials - TAP report 2.
TAP study group. (2001). Photodynamic therapy of subfoveal choroidal neovascularisation in age-related macular degeneration with verteporphin. Two-year results of 2 randomised clinical trials - TAP report 2.. Archives of Ophthalmology, 119, 198-201.
2000
Diabetic retinopathy screening
Owens, D. R., Gibbins, R. L., Kohner, E., Grimshaw, G. M., Greenwood, R., & Harding, S. (2000). Diabetic retinopathy screening. DIABETIC MEDICINE, 17(7), 493-494. doi:10.1046/j.1464-5491.2000.00333.x
Cost effectiveness analysis of screening for sight threatening diabetic eye disease
James, M., Turner, D. A., Broadbent, D. M., Vora, J., & Harding, S. P. (2000). Cost effectiveness analysis of screening for sight threatening diabetic eye disease. BRITISH MEDICAL JOURNAL, 320(7250), 1627-1631. doi:10.1136/bmj.320.7250.1627
Foveal translocation with secondary confluent laser for subfoveal CNV in AMD: 12 month follow up.
Wong, D., Harding, S., & Grierson, I. (2000). Foveal translocation with secondary confluent laser for subfoveal CNV in AMD: 12 month follow up.. The British journal of ophthalmology, 84(6), 670-671. doi:10.1136/bjo.84.6.667d
'Diabetic retinopathy in children: is screening worthwhile? '
Swain, J. Y. S., Broadbent, D. M., Dixon, S. F., Harding, S. P., Edward-Inatima, G., Chandna, A., . . . Smith, C. S. (2000). 'Diabetic retinopathy in children: is screening worthwhile? '. Diabetic Medicine, suppl(17), P69.
'Does stereoscopic macular photography improve the detection of macular oedema: a further sensitivity and specificity analysis'
Broadbent, D. M., Harding, S. P., James, M., & Vora, J. P. (2000). 'Does stereoscopic macular photography improve the detection of macular oedema: a further sensitivity and specificity analysis'. Diabetic Medicine, suppl(17), P56.
'How often should we screen for retinopathy in Type 2 diabetes? The Liverpool Diabetic Eye Study.'
Younis, N., Broadbent, D. M., Harding, S. P., & Vora, J. P. (2000). 'How often should we screen for retinopathy in Type 2 diabetes? The Liverpool Diabetic Eye Study.'. Diabetic Medicine, suppl(17), P72.
'Precision Low-Dose Proton Beam Radiotherapy Of Subfoveal Choroidal Neovascularisation In Age-Related Macular Degeneration: 12 Month Results of a Randomised Controlled Study.'
Briggs, M. C., Natha, S., Kacperek, A., Sen, J., Konegrud, S. K., Errington, D., . . . Harding, S. P. (2000). 'Precision Low-Dose Proton Beam Radiotherapy Of Subfoveal Choroidal Neovascularisation In Age-Related Macular Degeneration: 12 Month Results of a Randomised Controlled Study.'. Investigative Ophthalmology and Visual Science, 41, S812.
'Screening for diabetic retinopathy in children: screening, cost and prevalence - the Liverpool Diabetic Eye Study'
Broadbent, D. M., Dixon, S. F., Harding, S. P., Swain, J. Y. S., Edward-Inatima, G., Chandna, A., . . . Smith, C. S. (2000). 'Screening for diabetic retinopathy in children: screening, cost and prevalence - the Liverpool Diabetic Eye Study'. Investigative Ophthalmology and Visual Science, 41, S650.
Does fatal childhood cerebral malaria exist without retinopathy?
Hallett, C., Beare, N., Carr, R., Pollina, E., Kayira, K., Taylor, T., & Harding, S. (2000). Does fatal childhood cerebral malaria exist without retinopathy?. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 41(4), S780. Retrieved from https://www.webofscience.com/
Foveal translocation with secondary confluent laser for subfoveal CNV in AMD: 12 month follow up
Wong, D., Harding, S., & Grierson, I. (2000). Foveal translocation with secondary confluent laser for subfoveal CNV in AMD: 12 month follow up. BRITISH JOURNAL OF OPHTHALMOLOGY, 84(6), 670-671. Retrieved from https://www.webofscience.com/
Knowledge levels of diabetic eye disease in people with diabetes: results of a descriptive survey
Gillibrand, W. P., Broadbent, D. M., Swain, J. Y., Harding, S. P., & Vora, J. P. (2000). Knowledge levels of diabetic eye disease in people with diabetes: results of a descriptive survey. International Journal of Health Promotion and Education, 38(4), 141-144. doi:10.1080/14635240.2000.10806169
Retinopathy of cerebral malaria in Malawian children: Prognostic significance and natural history
Harding, S. P., Beare, N., Hallett, C. L., Lochhead, J., Challra, C., & Taylor, T. E. (2000). Retinopathy of cerebral malaria in Malawian children: Prognostic significance and natural history. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 41(4), S780. Retrieved from https://www.webofscience.com/
Screening for diabetic retinopathy.
Owens, D. R., Gibbins, R. L., Kohner, E., Grimshaw, G. M., Greenwood, R., & Harding, S. P. (2000). Screening for diabetic retinopathy.. Diabetic Medicine, 17(7), 493-494.
1999
A review of the spectrum of clinical ocular fundus findings in P-falciparum malaria in African children with a proposed classification and grading system
Lewallen, S., Harding, S. P., Ajewole, J., Schulenburg, W. E., Molyneux, M. E., Marsh, K., . . . Taylor, T. E. (1999). A review of the spectrum of clinical ocular fundus findings in P-falciparum malaria in African children with a proposed classification and grading system. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 93(6), 619-622. doi:10.1016/S0035-9203(99)90071-8
Dinucleotide repeat polymorphisms in <i>EDN1</i> and <i>NOS3</i> are not associated with severe diabetic retinopathy in type 1 or type 2 diabetes
Warpeha, K. M., Ah-Fat, F., Harding, S., Patterson, C. C., Xu, W., Hart, P. M., . . . Hughes, A. E. (1999). Dinucleotide repeat polymorphisms in <i>EDN1</i> and <i>NOS3</i> are not associated with severe diabetic retinopathy in type 1 or type 2 diabetes. EYE, 13, 174-178. doi:10.1038/eye.1999.46
Genotyping and functional analysis of a polymorphic (CCTTT)<sub>n</sub> repeat of NOS2A in diabetic retinopathy
Warpeha, K. M., Xu, W., Liu, L., Charles, I. G., Patterson, C. C., Ah-Fat, F., . . . Hughes, A. E. (1999). Genotyping and functional analysis of a polymorphic (CCTTT)<sub>n</sub> repeat of NOS2A in diabetic retinopathy. FASEB JOURNAL, 13(13), 1825-1832. doi:10.1096/fasebj.13.13.1825
Is it time for a national screening programme for sight-threatening diabetic retinopathy?
Hart, P. M., & Harding, S. (1999). Is it time for a national screening programme for sight-threatening diabetic retinopathy?. EYE, 13, 129-130. doi:10.1038/eye.1999.37
Prevalence of diabetic eye disease in an inner city population: the Liverpool Diabetic Eye Study
Broadbent, D. M., Scott, J. A., Vora, J. P., & Harding, S. P. (1999). Prevalence of diabetic eye disease in an inner city population: the Liverpool Diabetic Eye Study. EYE, 13, 160-165. doi:10.1038/eye.1999.43
1998
Pregnant, vomiting, and going blind
Tesfaye, S., Achari, V., Yang, Y. C., Harding, S., Bowden, A., & Vora, J. P. (1998). Pregnant, vomiting, and going blind. LANCET, 352(9140), 1594. doi:10.1016/S0140-6736(98)08325-1
Corneoscleral burn during phacoemulsification surgery
Majid, M. A., Sharma, M. K., & Harding, S. P. (1998). Corneoscleral burn during phacoemulsification surgery. JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 24(10), 1413-1415. doi:10.1016/S0886-3350(98)80239-3
1997
Visual acuity detects CSMO1? The value of visual acuity measurement in screening for diabetic maculopathy in the liverpool diabetic eye study
Harding, S. P., & Broadbent, D. M. (1997). Visual acuity detects CSMO1? The value of visual acuity measurement in screening for diabetic maculopathy in the liverpool diabetic eye study. Investigative Ophthalmology and Visual Science, 38(4).
Photographic and angiographic characterization of the retina of Kenyan children with severe malaria
Hero, M., Harding, S. P., Riva, C. E., Winstanley, P. A., Peshu, N., & Marsh, K. (1997). Photographic and angiographic characterization of the retina of Kenyan children with severe malaria. ARCHIVES OF OPHTHALMOLOGY, 115(8), 997-1003. doi:10.1001/archopht.1997.01100160167005
Bilateral multifocal choroiditis in Reiter syndrome
Needham, A. D., & Harding, S. P. (1997). Bilateral multifocal choroiditis in Reiter syndrome. ARCHIVES OF OPHTHALMOLOGY, 115(5), 684-685. doi:10.1001/archopht.1997.01100150686030
Hospital-based primary care centres in ophthalmology.
Rao, G. P., McGalliard, J. N., & Harding, S. P. (1997). Hospital-based primary care centres in ophthalmology.. Eye (London, England), 11 ( Pt 1), 1-2. doi:10.1038/eye.1997.1
1996
Detection of sight-threatening diabetic eye disease
Leese, G. P., Broadbent, D. M., Harding, S. P., & Vora, J. P. (1996). Detection of sight-threatening diabetic eye disease. DIABETIC MEDICINE, 13(10), 850-853. doi:3.0.CO;2-E">10.1002/(SICI)1096-9136(199610)13:10<850::AID-DIA167>3.0.CO;2-E
Authors' reply
Harding, S. P., Broadbent, D. M., & Vora, J. P. (1996). Authors' reply. BMJ, 312(7028), 440-441. doi:10.1136/bmj.312.7028.440c
Screening for sight threatening eye disease - Calculation of sensitivity is misleading
HickeyDwyer, M. (1996). Screening for sight threatening eye disease - Calculation of sensitivity is misleading. BRITISH MEDICAL JOURNAL, 312(7028), 440. Retrieved from https://www.webofscience.com/
Screening for sight threatening eye disease. Cost effectiveness of screening modalities must be determined.
Adab, P. (1996). Screening for sight threatening eye disease. Cost effectiveness of screening modalities must be determined.. BMJ (Clinical research ed.), 312(7028), 440. doi:10.1136/bmj.312.7028.440a
Detecting sight threatening diabetic eye disease in an inner city setting in the UK - The Liverpool Diabetic Eye Study
Scott, J. A., Harding, S. P., Broadbent, D. M., & Vora, J. (1996). Detecting sight threatening diabetic eye disease in an inner city setting in the UK - The Liverpool Diabetic Eye Study. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 37(3), 494. Retrieved from https://www.webofscience.com/
Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis
Birch, M. K., Barbosa, S., Blumhardt, L. D., OBrien, C., & Harding, S. P. (1996). Retinal venous sheathing and the blood-retinal barrier in multiple sclerosis. ARCHIVES OF OPHTHALMOLOGY, 114(1), 34-39. doi:10.1001/archopht.1996.01100130032005
Screening for sight threatening eye disease - Stereoscopic viewing of the retina needed to identify maculopathy - Reply
Harding, S. P., Broadbent, D. M., & Vora, J. P. (1996). Screening for sight threatening eye disease - Stereoscopic viewing of the retina needed to identify maculopathy - Reply. BRITISH MEDICAL JOURNAL, 312(7028), 440-441. Retrieved from https://www.webofscience.com/
1995
SCREENING FOR DIABETIC-RETINOPATHY - ADEQUATE PROGRAM WOULD SAVE MONEY
PARNABYPRICE, A. (1995). SCREENING FOR DIABETIC-RETINOPATHY - ADEQUATE PROGRAM WOULD SAVE MONEY. BRITISH MEDICAL JOURNAL, 311(7014), 1229. doi:10.1136/bmj.311.7014.1229a
SCREENING FOR DIABETIC-RETINOPATHY - APPROACHING 90-PERCENT SENSITIVITY WITH NEW TECHNIQUES
LEESE, G., BROADBENT, D., HARDING, S., & VORA, J. (1995). SCREENING FOR DIABETIC-RETINOPATHY - APPROACHING 90-PERCENT SENSITIVITY WITH NEW TECHNIQUES. BRITISH MEDICAL JOURNAL, 311(7014), 1230-1231. doi:10.1136/bmj.311.7014.1230c
SENSITIVITY AND SPECIFICITY OF PHOTOGRAPHY AND DIRECT OPHTHALMOSCOPY IN SCREENING FOR SIGHT THREATENING EYE DISEASE - THE LIVERPOOL DIABETIC EYE STUDY
HARDING, S. P., BROADBENT, D. M., NEOH, C., WHITE, M. C., & VORA, J. (1995). SENSITIVITY AND SPECIFICITY OF PHOTOGRAPHY AND DIRECT OPHTHALMOSCOPY IN SCREENING FOR SIGHT THREATENING EYE DISEASE - THE LIVERPOOL DIABETIC EYE STUDY. BMJ-BRITISH MEDICAL JOURNAL, 311(7013), 1131-1135. doi:10.1136/bmj.311.7013.1131
UNTITLED
HARDING, S. P. (1995). UNTITLED. EYE, 9, 390-391. doi:10.1038/eye.1995.89
Acyclovir and post-herpetic neuralgia. The balance of available evidence supports its use.
Harding, S. P. (1995). Acyclovir and post-herpetic neuralgia. The balance of available evidence supports its use.. BMJ (Clinical research ed.), 310(6985), 1005. doi:10.1136/bmj.310.6985.1005a
Acyclovir and post-herpetic neuralgia. Two other participating study centres report different results.
McKendrick, M. W., & Wood, M. J. (1995). Acyclovir and post-herpetic neuralgia. Two other participating study centres report different results.. BMJ (Clinical research ed.), 310(6985), 1005. doi:10.1136/bmj.310.6985.1005
Letter
Harding, S. P. (1995). Letter. Eye, 9(3), 390-391. doi:10.1038/eye.1995.89
Oral acyclovir in herpes zoster ophthalmicus.
Harding, S. P. (1995). Oral acyclovir in herpes zoster ophthalmicus.. Eye (London, England), 9 ( Pt 3), 390-392. doi:10.1038/eye.1995.89
1994
COMPARISON OF TOPICAL AND ORAL ACYCLOVIR IN EARLY HERPES-ZOSTER OPHTHALMICUS
NEOH, C., HARDING, S. P., SAUNDERS, D., WALLIS, S., TULLO, A. B., NYLANDER, A., & NELSON, M. E. (1994). COMPARISON OF TOPICAL AND ORAL ACYCLOVIR IN EARLY HERPES-ZOSTER OPHTHALMICUS. EYE, 8, 688-691. doi:10.1038/eye.1994.170
1993
DOUBLE-MASKED 3-PERIOD CROSSOVER INVESTIGATION OF TIMOLOL IN CONTROL OF RAISED INTRAOCULAR-PRESSURE
CAMPBELL, S. H., HICKEYDWYER, M., & HARDING, S. P. (1993). DOUBLE-MASKED 3-PERIOD CROSSOVER INVESTIGATION OF TIMOLOL IN CONTROL OF RAISED INTRAOCULAR-PRESSURE. EYE, 7, 105-108. doi:10.1038/eye.1993.22
MANAGEMENT OF OPHTHALMIC ZOSTER
HARDING, S. P. (1993). MANAGEMENT OF OPHTHALMIC ZOSTER. In JOURNAL OF MEDICAL VIROLOGY (pp. 97-101). Retrieved from https://www.webofscience.com/
VIRAL-INFECTIONS OF THE EYE
HARDING, S. P. (1993). VIRAL-INFECTIONS OF THE EYE. REVIEWS IN MEDICAL VIROLOGY, 3(3), 161-171. doi:10.1002/rmv.1980030306
1992
LONG-TERM DRIFT AND TIMOLOL THERAPY - POSSIBLE ROLE FOR PULSED THERAPY
BATTERBURY, M., HARDING, S. P., & WONG, D. (1992). LONG-TERM DRIFT AND TIMOLOL THERAPY - POSSIBLE ROLE FOR PULSED THERAPY. INTERNATIONAL OPHTHALMOLOGY, 16(4-5), 321-324. doi:10.1007/BF00917984
1991
A PROSPECTIVE-STUDY OF ORAL NADOLOL IN THE MANAGEMENT OF PATIENTS WITH NEWLY DIAGNOSED CHRONIC SIMPLE GLAUCOMA
DOWD, T. C., HARDING, S., & RENNIE, I. (1991). A PROSPECTIVE-STUDY OF ORAL NADOLOL IN THE MANAGEMENT OF PATIENTS WITH NEWLY DIAGNOSED CHRONIC SIMPLE GLAUCOMA. JOURNAL OF OCULAR PHARMACOLOGY, 7(1), 21-26. doi:10.1089/jop.1991.7.21
DOUBLED-MASKED 3-PERIOD CROSSOVER INVESTIGATION OF METIPRANOLOL IN CONTROL OF RAISED INTRAOCULAR-PRESSURE
HICKEYDWYER, M., CAMPBELL, S. H., & HARDING, S. (1991). DOUBLED-MASKED 3-PERIOD CROSSOVER INVESTIGATION OF METIPRANOLOL IN CONTROL OF RAISED INTRAOCULAR-PRESSURE. JOURNAL OF OCULAR PHARMACOLOGY, 7(4), 277-283. doi:10.1089/jop.1991.7.277
ORAL ACYCLOVIR IN HERPES-ZOSTER OPHTHALMICUS
HARDING, S. P., & PORTER, S. M. (1991). ORAL ACYCLOVIR IN HERPES-ZOSTER OPHTHALMICUS. CURRENT EYE RESEARCH, 10, 177-182. doi:10.3109/02713689109020376
1990
Herpes zoster ophthalmicus
Harding, S. P. (1990). Herpes zoster ophthalmicus. (PhD Thesis, University of Liverpool).
1988
EARLY ELECTRORETINOGRAPHY IN UNILATERAL CENTRAL RETINAL VEIN OCCLUSION AS A PREDICTOR OF RUBEOSIS IRIDIS
KAYE, S. B., & HARDING, S. P. (1988). EARLY ELECTRORETINOGRAPHY IN UNILATERAL CENTRAL RETINAL VEIN OCCLUSION AS A PREDICTOR OF RUBEOSIS IRIDIS. ARCHIVES OF OPHTHALMOLOGY, 106(3), 353-356. Retrieved from https://www.webofscience.com/
AN EPIDEMIC OF KERATOCONJUNCTIVITIS DUE TO ADENOVIRUS TYPE-37
HARDING, S. P., MUTTON, K. J., VANDERAVOORT, H., & WERMENBOL, A. G. (1988). AN EPIDEMIC OF KERATOCONJUNCTIVITIS DUE TO ADENOVIRUS TYPE-37. EYE, 2, 314-317. doi:10.1038/eye.1988.59
1987
Ophthalmia neonatorum.
Harding, S. P., Mallinson, H., & Roberts, C. (1987). Ophthalmia neonatorum.. The Journal of infectious diseases, 156(1), 249-250. doi:10.1093/infdis/156.1.249-a
NATURAL-HISTORY OF HERPES-ZOSTER OPHTHALMICUS - PREDICTORS OF POSTHERPETIC NEURALGIA AND OCULAR INVOLVEMENT
HARDING, S. P., LIPTON, J. R., & WELLS, J. C. D. (1987). NATURAL-HISTORY OF HERPES-ZOSTER OPHTHALMICUS - PREDICTORS OF POSTHERPETIC NEURALGIA AND OCULAR INVOLVEMENT. BRITISH JOURNAL OF OPHTHALMOLOGY, 71(5), 353-358. doi:10.1136/bjo.71.5.353
ADULT FOLLICULAR CONJUNCTIVITIS AND NEONATAL OPHTHALMIA IN A LIVERPOOL-EYE-HOSPITAL, 1980-1984
HARDING, S. P., MALLINSON, H., SMITH, J. L. S., & CLEARKIN, L. G. (1987). ADULT FOLLICULAR CONJUNCTIVITIS AND NEONATAL OPHTHALMIA IN A LIVERPOOL-EYE-HOSPITAL, 1980-1984. EYE-TRANSACTIONS OF THE OPHTHALMOLOGICAL SOCIETIES OF THE UNITED KINGDOM, 1, 512-521. doi:10.1038/eye.1987.77
1986
RELIEF OF ACUTE PAIN IN HERPES-ZOSTER OPHTHALMICUS BY STELLATE GANGLION BLOCK
HARDING, S. P., LIPTON, J. R., WELLS, J. C. D., & CAMPBELL, J. A. (1986). RELIEF OF ACUTE PAIN IN HERPES-ZOSTER OPHTHALMICUS BY STELLATE GANGLION BLOCK. BRITISH MEDICAL JOURNAL, 292(6533), 1428. doi:10.1136/bmj.292.6533.1428
The effect of early stellate ganglion block on postherpetic neuralgia in herpes zoster ophthalmicus
Lipton, J. R., Harding, S. P., & Wells, J. C. D. (1986). The effect of early stellate ganglion block on postherpetic neuralgia in herpes zoster ophthalmicus. Pain Clinic, 1(4), 247-251.