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2024

Management Approaches in WHO Grade III Meningioma: A National Oncology Trainees' Collaborative for Healthcare Research (NOTCH) UK Multi-Centre Retrospective Study.

Dobeson, C. B., Baxter, M., Rowe, M., Kingdon, S., Park, S., Bond, H., . . . National Oncology Trainees' Collaborative for Healthcare Research (NOTCH). (2024). Management Approaches in WHO Grade III Meningioma: A National Oncology Trainees' Collaborative for Healthcare Research (NOTCH) UK Multi-Centre Retrospective Study.. Clinical oncology (Royal College of Radiologists (Great Britain)), 36(9), e301-e311. doi:10.1016/j.clon.2024.05.006

DOI
10.1016/j.clon.2024.05.006
Journal article

Letter: Estimating the baseline local recurrence rate for a brain metastasis after neurosurgical resection.

Suppree, J. S., Kannan, S., Hughes, D. M., Jenkinson, M. D., & Zakaria, R. (2024). Letter: Estimating the baseline local recurrence rate for a brain metastasis after neurosurgical resection.. Clinical & experimental metastasis, 41(2), 155-157. doi:10.1007/s10585-024-10274-6

DOI
10.1007/s10585-024-10274-6
Journal article

2023

The Role of Intraoperative MRI in Resection of High-Grade Glioma Using 5-ALA: A Single-Center Case Series

Zakaria, R., Suki, D., Weinberg, J. S., & Prabhu, S. S. (n.d.). The Role of Intraoperative MRI in Resection of High-Grade Glioma Using 5-ALA: A Single-Center Case Series. Neurosurgery Practice, 4(4). doi:10.1227/neuprac.0000000000000070

DOI
10.1227/neuprac.0000000000000070
Journal article

Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI

Zakaria, R., Jenkinson, M. D., Radon, M., Das, K., Poptani, H., Rathi, N., & Rudland, P. S. (2023). Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI. CANCER IMMUNOLOGY IMMUNOTHERAPY. doi:10.1007/s00262-023-03499-z

DOI
10.1007/s00262-023-03499-z
Journal article

DO GENOMIC ALTERATIONS INflUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS

Gillespie, C., Mustafa, M., Richardson, G., Alam, A., Lee, K. S., Hughes, D., . . . Zakaria, R. (2023). DO GENOMIC ALTERATIONS INflUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS. Neuro-Oncology, 25(Supplement_3), iii6-iii7. doi:10.1093/neuonc/noad147.026

DOI
10.1093/neuonc/noad147.026
Journal article

INVESTIGATING LOCAL RECURRENCE IN SECONDARY BRAIN TUMOURS

Suppree, J., Jenkinson, M. D., & Zakaria, R. (2023). INVESTIGATING LOCAL RECURRENCE IN SECONDARY BRAIN TUMOURS. Neuro-Oncology, 25(Supplement_3), iii15-iii16. doi:10.1093/neuonc/noad147.064

DOI
10.1093/neuonc/noad147.064
Journal article

P11.02.B DO GENOMIC ALTERATIONS INFLUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER?

Gillespie, C. S., Mustafa, M. A., Richardson, G. E., Alam, A. M., Lee, K. S., Hughes, D. M., . . . Zakaria, R. (2023). P11.02.B DO GENOMIC ALTERATIONS INFLUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER?. Neuro-Oncology, 25(Supplement_2), ii71-ii72. doi:10.1093/neuonc/noad137.236

DOI
10.1093/neuonc/noad137.236
Journal article

P11.03.A DOES REGULAR SURVEILLANCE IMAGING IMPROVE SURVIVAL IN GLIOBLASTOMA? RESULTS FROM A NATIONAL, MULTI-CENTRE COHORT STUDY (INTERVAL-GB)

Gillespie, C. S., Bligh, E. R., Poon, M. T. C., Solomou, G., Gough, M., Islim, A. I., . . . Jenkinson, M. D. (2023). P11.03.A DOES REGULAR SURVEILLANCE IMAGING IMPROVE SURVIVAL IN GLIOBLASTOMA? RESULTS FROM A NATIONAL, MULTI-CENTRE COHORT STUDY (INTERVAL-GB). Neuro-Oncology, 25(Supplement_2), ii72. doi:10.1093/neuonc/noad137.237

DOI
10.1093/neuonc/noad137.237
Journal article

Genomic alterations and the incidence of brain metastases in advanced and metastatic non-small cell lung cancer: a systematic review and meta-analysis.

Gillespie, C. S., Mustafa, M. A., Richardson, G. E., Alam, A. M., Lee, K. S., Hughes, D. M., . . . Zakaria, R. (2023). Genomic alterations and the incidence of brain metastases in advanced and metastatic non-small cell lung cancer: a systematic review and meta-analysis.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, S1556-0864(23)00638-X. doi:10.1016/j.jtho.2023.06.017

DOI
10.1016/j.jtho.2023.06.017
Journal article

Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma

Hutchinson, P. J., Adams, H., Mohan, M., Devi, B. I., Uff, C., Hasan, S., . . . Kolias, A. G. (2023). Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma. NEW ENGLAND JOURNAL OF MEDICINE, 388(24), 2219-2229. doi:10.1056/NEJMoa2214172

DOI
10.1056/NEJMoa2214172
Journal article

Imaging Timing After Surgery for Glioblastoma (INTERVAL GB): A multi-centre, UK and Ireland retrospective cohort study

Bligh, E. R., Gillespie, C., Poon, M. T. C., Solomou, G., Gough, M., Islim, A. I., . . . Jenkinson, M. D. (2023). Imaging Timing After Surgery for Glioblastoma (INTERVAL GB): A multi-centre, UK and Ireland retrospective cohort study. Brain and Spine, 3, 102127. doi:10.1016/j.bas.2023.102127

DOI
10.1016/j.bas.2023.102127
Journal article

2022

Characterisation of the immune microenvironment of primary breast cancer and brain metastasis reveals depleted T-cell response associated to ARG2 expression

Giannoudis, A., Vareslija, D., Sharma, V., Zakaria, R., Platt-Higgins, A., Rudland, P. S., . . . Palmieri, C. (2022). Characterisation of the immune microenvironment of primary breast cancer and brain metastasis reveals depleted T-cell response associated to ARG2 expression. ESMO OPEN, 7(6). doi:10.1016/j.esmoop.2022.100636

DOI
10.1016/j.esmoop.2022.100636
Journal article

2021

Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

Glasbey, J. C., Ademuyiwa, A., Adisa, A., AlAmeer, E., Arnaud, A. P., Ayasra, F., . . . Aldawbali, M. (2021). Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. LANCET ONCOLOGY, 22(11), 1507-1517. doi:10.1016/S1470-2045(21)00493-9

DOI
10.1016/S1470-2045(21)00493-9
Journal article

Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival

Giannoudis, A., Sartori, A., Eastoe, L., Zakaria, R., Charlton, C., Hickson, N., . . . Palmieri, C. (2021). Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival. BREAST CANCER RESEARCH AND TREATMENT, 190(2), 241-253. doi:10.1007/s10549-021-06364-8

DOI
10.1007/s10549-021-06364-8
Journal article

Genomic Profiling Using The UltraSEEK Panel Identifies Discordancy Between Paired Primary And Breast Cancer Brain Metastases And An Association With Brain Metastasis-Free Survival

DOI
10.21203/rs.3.rs-377753/v1
Preprint

Letter to the Editor Regarding "Safety Analysis of Bilateral Laser Interstitial Thermal Therapy for Treatment of Butterfly Glioma"

Zakaria, R., & Prabhu, S. S. (2021). Letter to the Editor Regarding "Safety Analysis of Bilateral Laser Interstitial Thermal Therapy for Treatment of Butterfly Glioma". WORLD NEUROSURGERY, 147, 236-237. doi:10.1016/j.wneu.2020.10.161

DOI
10.1016/j.wneu.2020.10.161
Journal article

BMSCOPE: A SYSTEMATIC MAPPING REVIEW OF BRAIN/LEPTOMENINGEAL METASTASIS CLINICAL STUDIES FROM 2010 TO 2020

Cheng, V. W. T., Heywood, R., Zakaria, R., Burger, R., Fitzpatrick, A., Zucker, K., . . . Jenkinson, M. D. (2021). BMSCOPE: A SYSTEMATIC MAPPING REVIEW OF BRAIN/LEPTOMENINGEAL METASTASIS CLINICAL STUDIES FROM 2010 TO 2020. In NEURO-ONCOLOGY Vol. 23 (pp. 51). Retrieved from https://www.webofscience.com/

Conference Paper

Challenges Associated with Reoperation in Patients with Glioma.

Zakaria, R., & Weinberg, J. S. (2021). Challenges Associated with Reoperation in Patients with Glioma.. Neurosurgery clinics of North America, 32(1), 129-135. doi:10.1016/j.nec.2020.09.004

DOI
10.1016/j.nec.2020.09.004
Journal article

2020

Delaying surgery for patients with a previous SARS-CoV-2 infection

Delaying surgery for patients with a previous SARS-CoV-2 infection (2020). BRITISH JOURNAL OF SURGERY, 107(12), E601-E602. doi:10.1002/bjs.12050

DOI
10.1002/bjs.12050
Journal article

Does the application of diffusion weighted imaging improve the prediction of survival in patients with resected brain metastases? A retrospective multicenter study

Zakaria, R., Chen, Y. J., Hughes, D. M., Wang, S., Chawla, S., Poptani, H., . . . Mohan, S. (2020). Does the application of diffusion weighted imaging improve the prediction of survival in patients with resected brain metastases? A retrospective multicenter study. CANCER IMAGING, 20(1). doi:10.1186/s40644-020-0295-4

DOI
10.1186/s40644-020-0295-4
Journal article

2019

Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation

Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., . . . Gamble, C. (2019). Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation. Lancet, 394(10208), 1530-1539. doi:10.1016/S0140-6736(19)31603-4

DOI
10.1016/S0140-6736(19)31603-4
Journal article

Intracranial metastases

Brodbelt, A., & Zakaria, R. (2019). Intracranial metastases. In R. W. Kirollos, A. Helmy, S. Thomson, & P. J. A. Hutchinson (Eds.), Oxford Textbook of Neurological Surgery (pp. 107-116). Oxford University Press. doi:10.1093/med/9780198746706.003.0008

DOI
10.1093/med/9780198746706.003.0008
Chapter

INVESTIGATING IMMUNOTHERAPY AS AN ADJUNCT TO SURGERY FOR BRAIN METASTASES

Zakaria, R., & Jenkinson, M. D. (2019). INVESTIGATING IMMUNOTHERAPY AS AN ADJUNCT TO SURGERY FOR BRAIN METASTASES. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 90 (pp. E6-E7). doi:10.1136/jnnp-2019-ABN.20

DOI
10.1136/jnnp-2019-ABN.20
Conference Paper

Identification of microRNAs differentially expressed in brain metastasis secondary to breast cancer

Giannoudis, A., Clarke, K., Zakaria, R., Vareslija, D., Farahani, M., Rainbow, L., . . . Palmieri, C. (2019). Identification of microRNAs differentially expressed in brain metastasis secondary to breast cancer. In CANCER RESEARCH Vol. 79. doi:10.1158/1538-7445.SABCS18-P6-05-02

DOI
10.1158/1538-7445.SABCS18-P6-05-02
Conference Paper

2018

MNGI-07. THE ANAPLASTIC MENINGIOMA INTERNATIONAL CONSORTIUM (AMICo) RETROSPECTIVE STUDY OF TREATMENT AND OUTCOME OF PATIENTS WITH ANAPLASTIC MENINGIOMAS

di Bonaventura, R., Young, A., Zakaria, R., Champeaux, C., Foo, A., Tonn, J. -C., . . . Santarius, T. (2018). MNGI-07. THE ANAPLASTIC MENINGIOMA INTERNATIONAL CONSORTIUM (AMICo) RETROSPECTIVE STUDY OF TREATMENT AND OUTCOME OF PATIENTS WITH ANAPLASTIC MENINGIOMAS. Neuro-Oncology, 20(suppl_6), vi149. doi:10.1093/neuonc/noy148.623

DOI
10.1093/neuonc/noy148.623
Journal article

DIVERGENT CLONAL EVOLUTION OF MELANOMA BRAIN METASTASES DURING TREATMENT WITH IMMUNOTHERAPY

Alvarez-Breckenridge, C., Izar, B., Stocking, J., Lastrapes, M., Nayyar, N., Gill, C., . . . Brastianos, P. (2018). DIVERGENT CLONAL EVOLUTION OF MELANOMA BRAIN METASTASES DURING TREATMENT WITH IMMUNOTHERAPY. In NEURO-ONCOLOGY Vol. 20 (pp. 106-107). Retrieved from https://www.webofscience.com/

Conference Paper

2017

2016

Taking a neurological history

Kennedy, A., & Zakaria, R. (2016). Taking a neurological history. Medicine, 44(8), 459-463. doi:10.1016/j.mpmed.2016.05.003

DOI
10.1016/j.mpmed.2016.05.003
Journal article

Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth

Soto, M. S., O'Brien, E. R., Andreou, K., Scrace, S. F., Zakaria, R., Jenkinson, M. D., . . . Sibson, N. R. (2016). Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth. Oncotarget, 7(32), 52375-52391. doi:10.18632/oncotarget.10737

DOI
10.18632/oncotarget.10737
Journal article

Management of Typical and Atypical Hangman's Fractures.

Al-Mahfoudh, R., Beagrie, C., Woolley, E., Zakaria, R., Radon, M., Clark, S., . . . Wilby, M. (2016). Management of Typical and Atypical Hangman's Fractures. GLOBAL SPINE JOURNAL, 6(3), 248-256. doi:10.1055/s-0035-1563404

DOI
10.1055/s-0035-1563404
Journal article

Metastasis-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response

Zakaria, R., Platt-Higgins, A., Rathi, N., Crooks, D., Brodbelt, A., Chavredakis, E., . . . Rudland, P. S. (2016). Metastasis-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response. British Journal of Cancer, 114(10), 1101-1108. doi:10.1038/bjc.2016.103

DOI
10.1038/bjc.2016.103
Journal article

2015

Prognostic Factors in Lobar World Health Organization Grade II Astrocytomas

Waqar, M., Hanif, S., Brodbelt, A. R., Rathi, N., Das, K., Zakaria, R., . . . Jenkinson, M. D. (2015). Prognostic Factors in Lobar World Health Organization Grade II Astrocytomas. WORLD NEUROSURGERY, 84(1), 154-162. doi:10.1016/j.wneu.2015.02.045

DOI
10.1016/j.wneu.2015.02.045
Journal article

Conservative management of type II and III odontoid fractures in the elderly at a regional spine centre: A prospective and retrospective cohort study

Patel, A., Zakaria, R., Al-Mahfoudh, R., Clark, S., Barrett, C., Sarsam, Z., . . . Wilby, M. J. (2015). Conservative management of type II and III odontoid fractures in the elderly at a regional spine centre: A prospective and retrospective cohort study. BRITISH JOURNAL OF NEUROSURGERY, 29(2), 249-253. doi:10.3109/02688697.2014.958055

DOI
10.3109/02688697.2014.958055
Journal article

Atypical meningoma: current management dilemmas and prospective clinical trials

Jenkinson, M. D., Weber, D. C., Haylock, B. J., Mallucci, C. L., Zakaria, R., & Javadpour, M. (2015). Atypical meningoma: current management dilemmas and prospective clinical trials. JOURNAL OF NEURO-ONCOLOGY, 121(1), 1-7. doi:10.1007/s11060-014-1620-1

DOI
10.1007/s11060-014-1620-1
Journal article

Diffusion weighted MRI is a promising imaging biomarker in brain metastases

Zakaria, R., & Jenkinson, M. D. (2015). Diffusion weighted MRI is a promising imaging biomarker in brain metastases. JOURNAL OF NEURO-ONCOLOGY, 121(2), 421-422. doi:10.1007/s11060-014-1642-8

DOI
10.1007/s11060-014-1642-8
Journal article

2014

Radiotherapy versus Observation following surgical resection of Atypical Meningioma (the ROAM trial)

Jenkinson, M. D., Weber, D. C., Haylock, B. J., Mallucci, C. L., Zakaria, R., & Javadpour, M. (2014). Radiotherapy versus Observation following surgical resection of Atypical Meningioma (the ROAM trial). NEURO-ONCOLOGY, 16(11), 1560-1561. doi:10.1093/neuonc/nou149

DOI
10.1093/neuonc/nou149
Journal article

Diagnostic challenges, management and outcomes of midline low-grade gliomas

Waqar, M., Hanif, S., Rathi, N., Das, K., Zakaria, R., Brodbelt, A. R., . . . Jenkinson, M. D. (2014). Diagnostic challenges, management and outcomes of midline low-grade gliomas. JOURNAL OF NEURO-ONCOLOGY, 120(2), 389-398. doi:10.1007/s11060-014-1563-6

DOI
10.1007/s11060-014-1563-6
Journal article

Diffusion-weighted MRI characteristics of the cerebral metastasis to brain boundary predicts patient outcomes

Zakaria, R., Das, K., Radon, M., Bhojak, M., Rudland, P. R., Sluming, V., & Jenkinson, M. D. (2014). Diffusion-weighted MRI characteristics of the cerebral metastasis to brain boundary predicts patient outcomes. BMC MEDICAL IMAGING, 14. doi:10.1186/1471-2342-14-26

DOI
10.1186/1471-2342-14-26
Journal article

Using ADC Maps with Structural Scans to Improve Intraoperative Biopsy Specimens in Brain Metastases.

Zakaria, R., & Jenkinson, M. D. (2014). Using ADC Maps with Structural Scans to Improve Intraoperative Biopsy Specimens in Brain Metastases.. The neuroradiology journal, 27(4), 422-424. doi:10.15274/nrj-2014-10075

DOI
10.15274/nrj-2014-10075
Journal article

The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis

Zakaria, R., Das, K., Bhojak, M., Radon, M., Walker, C., & Jenkinson, M. D. (2014). The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis. CANCER IMAGING, 14. doi:10.1186/1470-7330-14-8

DOI
10.1186/1470-7330-14-8
Journal article

The reliability of routine clinical post-processing software in assessing potential diffusion-weighted MRI “biomarkers” in brain metastases

Zakaria, R., Das, K., Bhojak, M., Radon, M., Sluming, V., Walker, C., & Jenkinson, M. D. (2014). The reliability of routine clinical post-processing software in assessing potential diffusion-weighted MRI “biomarkers” in brain metastases. Magnetic Resonance Imaging, 32(3), 291-296. doi:10.1016/j.mri.2013.12.010

DOI
10.1016/j.mri.2013.12.010
Journal article

2013

Tremor reduction and quality of life after deep brain stimulation for multiple sclerosis-associated tremor

Zakaria, R., Vajramani, G., Westmoreland, L., Fletcher, N., Eldridge, P., Alusi, S., & Osman-Farah, J. (2013). Tremor reduction and quality of life after deep brain stimulation for multiple sclerosis-associated tremor. ACTA NEUROCHIRURGICA, 155(12), 2359-2364. doi:10.1007/s00701-013-1848-0

DOI
10.1007/s00701-013-1848-0
Journal article

Thalamic physiology of intentional essential tremor is more like cerebellar tremor than postural essential tremor

Zakaria, R., Lenz, F. A., Hua, S., Avin, B. H., Liu, C. C., & Mari, Z. (2013). Thalamic physiology of intentional essential tremor is more like cerebellar tremor than postural essential tremor. BRAIN RESEARCH, 1529, 188-199. doi:10.1016/j.brainres.2013.07.011

DOI
10.1016/j.brainres.2013.07.011
Journal article

Reduction of drain-associated cerebrospinal fluid infections in neurosurgical inpatients: a prospective study

Zakaria, R., Tripathy, S., Srikandarajah, N., Rothburn, M. M., & Lawson, D. D. A. (2013). Reduction of drain-associated cerebrospinal fluid infections in neurosurgical inpatients: a prospective study. JOURNAL OF HOSPITAL INFECTION, 84(3), 215-221. doi:10.1016/j.jhin.2013.03.008

DOI
10.1016/j.jhin.2013.03.008
Journal article

PRE-OPERATIVE MRI DIFFUSION CHARACTERISTICS OF THE TUMOUR AND PERITUMORAL REGION MAY PREDICT SURVIVAL AND LOCAL RECURRENCE FOR OPERATED BRAIN METASTASES

Zakaria, R., Das, K., Sluming, V., Bhojak, M., Walker, C., & Jenkinson, M. D. (2013). PRE-OPERATIVE MRI DIFFUSION CHARACTERISTICS OF THE TUMOUR AND PERITUMORAL REGION MAY PREDICT SURVIVAL AND LOCAL RECURRENCE FOR OPERATED BRAIN METASTASES. In NEURO-ONCOLOGY Vol. 15 (pp. 205). Retrieved from https://www.webofscience.com/

Conference Paper

2012

Raised intracranial pressure and hydrocephalus following hindbrain decompression for Chiari I malformation: a case series and review of the literature

Zakaria, R., Kandasamy, J., Khan, Y., Jenkinson, M. D., Hall, S. R., Brodbelt, A., . . . Mallucci, C. L. (2012). Raised intracranial pressure and hydrocephalus following hindbrain decompression for Chiari I malformation: a case series and review of the literature. BRITISH JOURNAL OF NEUROSURGERY, 26(4), 476-481. doi:10.3109/02688697.2011.650738

DOI
10.3109/02688697.2011.650738
Journal article

2011

2009

Serotonin Depletion Impairs Waiting but not Stop-Signal Reaction Time in Rats: Implications for Theories of the Role of 5-HT in Behavioral Inhibition

Eagle, D. M., Lehmann, O., Theobald, D. E. H., Pena, Y., Zakaria, R., Ghosh, R., . . . Robbins, T. W. (2009). Serotonin Depletion Impairs Waiting but not Stop-Signal Reaction Time in Rats: Implications for Theories of the Role of 5-HT in Behavioral Inhibition. NEUROPSYCHOPHARMACOLOGY, 34(5), 1311-1321. doi:10.1038/npp.2008.202

DOI
10.1038/npp.2008.202
Journal article