Publications
2021
Temporal modulation of the NF-kappa B ReIA network in response to different types of DNA damage
Campbell, A. E., Franco, C. F., Ling-I, S., Corbin, E. K., Perkins, S., Kalyuzhnyy, A., . . . Eyers, C. E. (2021). Temporal modulation of the NF-kappa B ReIA network in response to different types of DNA damage. Biochemical Journal, 478(3), 533-551. doi:10.1042/BCJ20200627
2020
CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis
Wall, E. C., Brownridge, P., Laing, G., Terra, V. S., Mlozowa, V., Denis, B., . . . Brown, J. S. (2020). CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 10. doi:10.3389/fcimb.2020.603623
Social status and ejaculate composition in the house mouse
Bayram, H., Franco, C., Brownridge, P., Claydon, A., Koch, N., Hurst, J., . . . Stockley, P. (2020). Social status and ejaculate composition in the house mouse. Philosophical Transactions of the Royal Society B: Biological Sciences, 375(1813). doi:10.1098/rstb.2020.0083
Revealing mechanisms of mating plug function under sexual selection
Stockley, P., Franco, C., Claydon, A., Davidson, A., Hammond, D., Brownridge, P., . . . Beynon, R. (2020). Revealing mechanisms of mating plug function under sexual selection. Proceedings of the National Academy of Sciences of USA, 117(44), 27465-27473. doi:10.1073/pnas.1920526117
PEPPI-MS: Polyacrylamide-Gel-Based Prefractionation for Analysis of Intact Proteoforms and Protein Complexes by Mass Spectrometry
Takemori, A., Butcher, D. S., Harman, V. M., Brownridge, P., Shima, K., Higo, D., . . . Takemori, N. (2020). PEPPI-MS: Polyacrylamide-Gel-Based Prefractionation for Analysis of Intact Proteoforms and Protein Complexes by Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH, 19(9), 3779-3791. doi:10.1021/acs.jproteome.0c00303
Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics
Byrne, D. P., Clarke, C. J., Brownridge, P. J., Kalyuzhnyy, A., Perkins, S., Campbell, A., . . . Eyers, C. E. (2020). Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics. The Biochemical journal, 477(13), 2451-2475. doi:10.1042/bcj20200309
Decoding the stoichiometric composition and organisation of bacterial metabolosomes
Yang, M., Simpson, D., Wenner, N., Brownridge, P., Harman, V., Hinton, J., . . . Liu, L. (2020). Decoding the stoichiometric composition and organisation of bacterial metabolosomes. Nature Communications, 11(1). doi:10.1038/s41467-020-15888-4
Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke <i>Schistosoma mansoni</i> Pinpoints Secreted Proteins for Vaccine Development
Neves, L. X., Wilson, R. A., Brownridge, P., Harman, V. M., Holman, S. W., Beynon, R. J., . . . Castro-Borges, W. (2020). Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke <i>Schistosoma mansoni</i> Pinpoints Secreted Proteins for Vaccine Development. JOURNAL OF PROTEOME RESEARCH, 19(1), 314-326. doi:10.1021/acs.jproteome.9b00531
Large scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont
Darby, A. C., Goodhead, I., Blow, F., Brownridge, P., Hughes, M., Kenny, J., . . . Beynon, R. (2020). Large scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont. Microbial Genomics, 6(1), 3-15. doi:10.1099/mgen.0.000285
2019
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation
Hardman, G., Perkins, S., Brownridge, P., Clarke, C., Byrne, D., Campbell, A., . . . Eyers, C. (2019). Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation. The EMBO Journal, 38(21). doi:10.15252/embj.2018100847
The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis
Nunes, Q. M., Su, D., Brownridge, P. J., Simpson, D. M., Sun, C., Li, Y., . . . Fernig, D. G. (2019). The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. PLOS ONE, 14(6). doi:10.1371/journal.pone.0217633
Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580
Canals, R., Hammarlöf, D. L., Kröger, C., Owen, S. V., Fong, W. Y., Lacharme-Lora, L., . . . Hinton, J. C. D. (2019). Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580. PLoS Biology, 17(1). doi:10.1371/journal.pbio.3000059
2018
The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis
Nunes, Q., Su, D., Brownridge, P., Simpson, D., Sun, C., Li, Y., . . . Fernig, D. (2018). The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. doi:10.1101/497271
2017
Evaluation of Parameters for Confident Phosphorylation Site Localization using an Orbitrap Fusion Tribrid Mass Spectrometer
Ferries., Perkins, S., Brownridge., Campbell, A., Eyers, P., Jones, A., & Eyers, C. E. (2017). Evaluation of Parameters for Confident Phosphorylation Site Localization using an Orbitrap Fusion Tribrid Mass Spectrometer. Journal of Proteome Research, 16(9), 3448-3459. doi:10.1021/acs.jproteome.7b00337
DOSCATs: Double standards for protein quantification
Bennett, R. J., Simpson, D. M., Holman, S. W., Ryan, S., Brownridge, P., Eyers, C. E., . . . Beynon, R. J. (2017). DOSCATs: Double standards for protein quantification. Scientific Reports, 7. doi:10.1038/srep45570
2016
cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry
Byrne, D. P., Vonderach, M., Ferries, S., Brownridge, P. J., Eyers, C. E., & Eyers, P. A. (2016). cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry. BIOCHEMICAL JOURNAL, 473, 3159-3175. doi:10.1042/BCJ20160648
Cross-species proteomics in analysis of mammalian sperm proteins
Bayram, H., Claydon, A., Brownridge, P., Hurst, J., Mileham, A., Stockley, P., . . . Hammond, D. (2016). Cross-species proteomics in analysis of mammalian sperm proteins. Journal of Proteomics, 135, 38-50. doi:10.1016/j.jprot.2015.12.027
Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring
Lawless, C., Holman, S. W., Brownridge, P., Lanthaler, K., Harman, V. M., Watkins, R., . . . Hubbard, S. J. (2016). Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring. Molecular and Cellular Proteomics, 15(4), 1309-1322. doi:10.1074/mcp.M115.054288
The Heparin-Binding Proteome in Murine Experimental Acute Pancreatitis
Nunes, Q. M., Su, D., Brownridge, P. J., Sun, C., Li, Y., Huang, W., . . . Fernig, D. G. (2016). The Heparin-Binding Proteome in Murine Experimental Acute Pancreatitis. PANCREAS, 45(10), 1530. Retrieved from https://www.webofscience.com/
2015
Sperm competition risk drives plasticity in seminal fluid composition
Ramm, S., Edward, D., Claydon, A., Hammond, D., Brownridge, P., Hurst, J., . . . Stockley, P. (2015). Sperm competition risk drives plasticity in seminal fluid composition. BMC Biology, 13. doi:10.1186/s12915-015-0197-2
Redox proteomic analysis of the gastrocnemius muscle from adult and old mice
McDonagh, B., Sakellariou, G. K., Smith, N. T., Brownridge, P., & Jackson, M. J. (2015). Redox proteomic analysis of the gastrocnemius muscle from adult and old mice. DATA IN BRIEF, 4, 344-348. doi:10.1016/j.dib.2015.06.012
Redox proteomic analysis of the gastrocnemius muscle from adult and old mice.
McDonagh, B., Sakellariou, Y., Smith, N., Brownridge, P., & Jackson, M. (n.d.). Redox proteomic analysis of the gastrocnemius muscle from adult and old mice.. Redox proteomic analysis of the gastrocnemius muscle from adult and old mice..
2014
Development of a Method for Absolute Quantification of Equine Acute Phase Proteins Using Concatenated Peptide Standards and Selected Reaction Monitoring
Bundgaard, L., Jacobsen, S., Dyrlund, T. F., Sorensen, M. A., Harman, V. M., Beynon, R. J., . . . Bendixen, E. (2014). Development of a Method for Absolute Quantification of Equine Acute Phase Proteins Using Concatenated Peptide Standards and Selected Reaction Monitoring. JOURNAL OF PROTEOME RESEARCH, 13(12), 5635-5647. doi:10.1021/pr500607s
Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging
McDonagh, B., Sakellariou, G., Smith, N., Brownridge, P., & Jackson, M. (2014). Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging. Journal of Proteome Research, 13(11), 5008-5021. doi:10.1021/pr5006394
Absolute Quantification of over 1900 Yeast Proteins Provide Insights into Translational Control and Protein Dynamics
Lawless, C., Holman, S. W., Brownridge, P., Lanthaler1, K., Harman, V. M., Watkins, R., . . . Hubbard, S. J. (2014). Absolute Quantification of over 1900 Yeast Proteins Provide Insights into Translational Control and Protein Dynamics.
2013
Quantitative analysis of chaperone network throughput in budding yeast
Brownridge, P., Lawless, C., Payapilly, A. B., Lanthaler, K., Holman, S. W., Harman, V. M., . . . Hubbard, S. J. (2013). Quantitative analysis of chaperone network throughput in budding yeast. PROTEOMICS, 13(8), 1276-1291. doi:10.1002/pmic.201200412
2012
A Software Toolkit and Interface for Performing Stable Isotope Labeling and Top3 Quantification Using Progenesis LC-MS
Qi, D., Brownridge, P., Xia, D., Mackay, K., Gonzalez-Galarza, F. F., Kenyani, J., . . . Jones, A. R. (2012). A Software Toolkit and Interface for Performing Stable Isotope Labeling and Top3 Quantification Using Progenesis LC-MS. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 16(9), 489-495. doi:10.1089/omi.2012.0042
Absolute multiplexed protein quantification using QconCAT technology.
Brownridge, P. J., Harman, V. M., Simpson, D. M., & Beynon, R. J. (2012). Absolute multiplexed protein quantification using QconCAT technology.. Methods in molecular biology (Clifton, N.J.), 893, 267-293. doi:10.1007/978-1-61779-885-6_18
A proteomics strategy for determining the synthesis and degradation rates of individual proteins in fish
Doherty, M. K., Brownridge, P., Owen, M. A. G., Davies, S. J., Young, I. S., & Whitfield, P. D. (2012). A proteomics strategy for determining the synthesis and degradation rates of individual proteins in fish. JOURNAL OF PROTEOMICS, 75(14), 4471-4477. doi:10.1016/j.jprot.2012.03.025
2011
Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH
Carroll, K. M., Simpson, D. M., Eyers, C. E., Knight, C. G., Brownridge, P., Dunn, W. B., . . . Beynon, R. J. (2011). Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH. MOLECULAR & CELLULAR PROTEOMICS, 10(12). doi:10.1074/mcp.M111.007633
Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy
Brownridge, P., Holman, S. W., Gaskell, S. J., Grant, C. M., Harman, V. M., Hubbard, S. J., . . . Beynon, R. J. (2011). Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy. PROTEOMICS, 11(15), 2957-2970. doi:10.1002/pmic.201100039
The importance of the digest: Proteolysis and absolute quantification in proteomics
Brownridge, P., & Beynon, R. J. (2011). The importance of the digest: Proteolysis and absolute quantification in proteomics. METHODS, 54(4), 351-360. doi:10.1016/j.ymeth.2011.05.005
Absolute Multiplexed Protein Quantification Using QconCAT technology
Brownridge, P. J., Harman, V., Simpson, D. M., & Beynon, R. J. (2011). Absolute Multiplexed Protein Quantification Using QconCAT technology. In K. Marcus (Ed.), Quantitative Methods in Proteomics (pp. 100-115). New York: Humana Press.
Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH
Carroll, K. M., Simpson, D. M., Eyers, C. E., Knight, C. G., Brownridge, P., Dunn, W. B., . . . Beynon, R. J. (2011). Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH. Molecular & Cellular Proteomics, 10(12). doi:10.1074/mcp.M111.007633-1
Alternative routes to absolute protein quantification
Brownridge, P. J., Harman, V. M., Lawless, C., Lanthaler, K., Watkins, R., Holman, S. W., . . . Beynon, R. J. (2011). Alternative routes to absolute protein quantification. In 8th BSPR-EBI Meeting 'From the visible to the hidden proteome' (pp. Poster). Cambridge, UK: BSPR-EBI Meeting.
Large scale production of QconCAT standards for quantitative proteomics
Harman, V., Watkins, R. H., Brownridge, P., Holman, S. W., Lanthaler, K., Lawless, C., . . . Beynon, R. (2011). Large scale production of QconCAT standards for quantitative proteomics. In 8th BSPR-EBI Meeting 'From the visible to the hidden proteome' (pp. Poster). Cambridge, UK: BSPR-EBI Meeting.
2010
Degradative proteomics and disease mechanisms
Lanucara, F., Brownridge, P., Young, I. S., Whitfield, P. D., & Doherty, M. K. (2010). Degradative proteomics and disease mechanisms. PROTEOMICS CLINICAL APPLICATIONS, 4(2), 133-142. doi:10.1002/prca.200900159
2009
Regional variation in parvalbumin isoform expression correlates with muscle performance in common carp (<i>Cyprinus carpio</i>)
Brownridge, P., de Mello, L. V., Peters, M., McLean, L., Claydon, A., Cossins, A. R., . . . Young, I. S. (2009). Regional variation in parvalbumin isoform expression correlates with muscle performance in common carp (<i>Cyprinus carpio</i>). JOURNAL OF EXPERIMENTAL BIOLOGY, 212(2), 184-193. doi:10.1242/jeb.021857
2008
Integrating proteomics with physiology: The influence of parvalbumin isoforms on fish muscle performance
Brownridge, P., Peters, M., de Mello, L. V., Cossins, A. R., Whitfield, P. D., & Young, I. S. (2008). Integrating proteomics with physiology: The influence of parvalbumin isoforms on fish muscle performance. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 150(3), S75-S76. doi:10.1016/j.cbpa.2008.04.113