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Paul McNamara

Professor Paul McNamara
MBBS FRCPCH PhD

Professor in Child Health, Consultant in Paediatric Respiratory Medicine
Women's & Children's Health

Publications

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2024

2023

Investigating markers of pulmonary aspiration in bronchoalveolar lavage from children with severe neurodisability

DOI
10.1101/2023.10.03.23295956
Preprint

Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings in Merseyside, Cheshire and Bristol, UK

Fyles, F., Hill, H., Duncan, G., Carter, E., Solorzano, C., Davies, K., . . . Collins, A. M. (2023). Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings in Merseyside, Cheshire and Bristol, UK. BMJ OPEN RESPIRATORY RESEARCH, 10(1). doi:10.1136/bmjresp-2022-001457

DOI
10.1136/bmjresp-2022-001457
Journal article

Respiratory Viruses and Atypical Bacteria

McNamara, P. S., Doorn, H. R. V., Adetifa, I. M. O., & Nokes, D. J. (2024). Respiratory Viruses and Atypical Bacteria. In Manson's Tropical Diseases (pp. 254-267). Elsevier. doi:10.1016/b978-0-7020-7959-7.00025-7

DOI
10.1016/b978-0-7020-7959-7.00025-7
Chapter

2022

Quantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis

Maher, R. E., Maatta, M., Beynon, R. J., Laurila, H. P., McNamara, P. S., & Rajamaki, M. M. (2022). Quantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis. BMC VETERINARY RESEARCH, 18(1). doi:10.1186/s12917-022-03202-x

DOI
10.1186/s12917-022-03202-x
Journal article

Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop

Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., Compton, V., Fernandes, R. M., . . . McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), e052943. doi:10.1136/bmjopen-2021-052943

DOI
10.1136/bmjopen-2021-052943
Journal article

Measuring the effect of elexacaftor/tezacaftor/ivacaftor combination therapy on the respiratory pump in people with CF using dynamic chest radiography

FitzMaurice, T. S., McCann, C., Nazareth, D., Shaw, M., McNamara, P. S., & Walshaw, M. J. (2022). Measuring the effect of elexacaftor/tezacaftor/ivacaftor combination therapy on the respiratory pump in people with CF using dynamic chest radiography. Journal of Cystic Fibrosis. doi:10.1016/j.jcf.2022.01.007

DOI
10.1016/j.jcf.2022.01.007
Journal article

2021

160: Using dynamic chest radiography to assess response to treatment in acute pulmonary exacerbations of adult people with cystic fibrosis

FitzMaurice, T., McCann, C., Nazareth, D., Walshaw, M., & McNamara, P. (2021). 160: Using dynamic chest radiography to assess response to treatment in acute pulmonary exacerbations of adult people with cystic fibrosis. Journal of Cystic Fibrosis, 20, S79. doi:10.1016/s1569-1993(21)01585-x

DOI
10.1016/s1569-1993(21)01585-x
Journal article

547: Characterization of diaphragm and chest wall mechanics in people with CF using dynamic chest radiography: Initial experiences

FitzMaurice, T., McCann, C., Nazareth, D., Walshaw, M., & McNamara, P. (2021). 547: Characterization of diaphragm and chest wall mechanics in people with CF using dynamic chest radiography: Initial experiences. Journal of Cystic Fibrosis, 20, S258-S259. doi:10.1016/s1569-1993(21)01970-6

DOI
10.1016/s1569-1993(21)01970-6
Journal article

Early Life Respiratory Infection

Patel, L. B., Legg, J. P., & McNamara, P. S. (2022). Early Life Respiratory Infection. In Encyclopedia of Respiratory Medicine (pp. 110-118). Elsevier. doi:10.1016/b978-0-08-102723-3.00195-5

DOI
10.1016/b978-0-08-102723-3.00195-5
Chapter

P102 Utility of Dynamic Chest Radiography (DCR) for calculating lung volume subdivisions in adult people with cystic fibrosis

FitzMaurice, T. S., Nazareth, D., McCann, C., Walshaw, M., & McNamara, P. S. (2021). P102 Utility of Dynamic Chest Radiography (DCR) for calculating lung volume subdivisions in adult people with cystic fibrosis. Journal of Cystic Fibrosis, 20, S70. doi:10.1016/s1569-1993(21)01128-0

DOI
10.1016/s1569-1993(21)01128-0
Journal article

2020

Modified Vaccinia Ankara–Vectored Vaccine Expressing Nucleoprotein and Matrix Protein 1 (M1) Activates Mucosal M1-Specific T-Cell Immunity and Tissue-Resident Memory T Cells in Human Nasopharynx-Associated Lymphoid Tissue

Puksuriwong, S., Ahmed, M. S., Sharma, R., Krishnan, M., Leong, S., Lambe, T., . . . Zhang, Q. (2020). Modified Vaccinia Ankara–Vectored Vaccine Expressing Nucleoprotein and Matrix Protein 1 (M1) Activates Mucosal M1-Specific T-Cell Immunity and Tissue-Resident Memory T Cells in Human Nasopharynx-Associated Lymphoid Tissue. The Journal of infectious diseases, 222(5), 807-819. doi:10.1093/infdis/jiz593

DOI
10.1093/infdis/jiz593
Journal article

Utility and validity of dynamic chest radiography in cystic fibrosis (dynamic CF): an observational, non-controlled, non-randomised, single-centre, prospective study.

FitzMaurice, T. S., McNamara, P. S., Nazareth, D., McCann, C., Bedi, R., Shaw, M., & Walshaw, M. (2020). Utility and validity of dynamic chest radiography in cystic fibrosis (dynamic CF): an observational, non-controlled, non-randomised, single-centre, prospective study.. BMJ Open Respir Res, 7(1). doi:10.1136/bmjresp-2020-000569

DOI
10.1136/bmjresp-2020-000569
Journal article

2019

Adherence to Aerosol Therapy in Young People With Cystic Fibrosis: Patient and Parent Perspectives Following Electronic Data Capture.

O'Toole, D. P. H., Latchford, G. J., Duff, A. J. A., Ball, R., McCormack, P., McNamara, P. S., . . . Southern, K. W. (2019). Adherence to Aerosol Therapy in Young People With Cystic Fibrosis: Patient and Parent Perspectives Following Electronic Data Capture. QUALITATIVE HEALTH RESEARCH, 29(6), 846-856. doi:10.1177/1049732318805754

DOI
10.1177/1049732318805754
Journal article

Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan

Reiné, J., Carniel, B., Solórzano, C., Mitsi, E., Pojar, S., Nikolaou, E., . . . Jochems, S. (2019). Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan. doi:10.1101/576744

DOI
10.1101/576744
Journal article

Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry

Gardner, A. I., McClenaghan,, E., Saint, G., Mcnamara, P. S., Brodlie, M., & Thomas, M. F. (2019). Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry. Clinical Infectious Diseases, 68(05), 731-737. doi:10.1093/cid/ciy531

DOI
10.1093/cid/ciy531
Journal article

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018)

Dunning, J., Blankley, S., Hoang, L. T., Cox, M., Graham, C. M., James, P. L., . . . Griffiths, M. J. (2019). Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018). NATURE IMMUNOLOGY, 20(3), 373. doi:10.1038/s41590-019-0328-y

DOI
10.1038/s41590-019-0328-y
Journal article

2018

Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response

Aljurayyan, A., Puksuriwong, S., Ahmed, M., Sharma, R., Krishnan, M., Sood, S., . . . Zhang, Q. (2018). Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response. Journal of virology, 92(11). doi:10.1128/jvi.00114-18

DOI
10.1128/jvi.00114-18
Journal article

2017

M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza

Cole, S. L., Dunning, J., Kok, W. L., Benam, K. H., Benlahrech, A., Repapi, E., . . . Ho, L. -P. (2017). M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. JCI INSIGHT, 2(7). doi:10.1172/jci.insight.91868

DOI
10.1172/jci.insight.91868
Journal article

2016

A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA

Aljurayyan, A. N., Sharma, R., Upile, N., Beer, H., Vaughan, C., Xie, C., . . . Zhang, Q. (2016). A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA. ANTIVIRAL RESEARCH, 132, 122-130. doi:10.1016/j.antiviral.2016.05.021

DOI
10.1016/j.antiviral.2016.05.021
Journal article

Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells

Hackett, A. M., Trinick, R. E., Rose, K., Flanagan, B. F., & McNamara, P. S. (2016). Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells. Respiratory Research, 17. doi:10.1186/s12931-016-0399-3

DOI
10.1186/s12931-016-0399-3
Journal article

Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue <i>in vitro</i> by Modified Vaccinia Ankara-vectored influenza vaccines

Mullin, J., Ahmed, M. S., Sharma, R., Upile, N., Beer, H., Achar, P., . . . Zhang, Q. (2016). Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue <i>in vitro</i> by Modified Vaccinia Ankara-vectored influenza vaccines. VACCINE, 34(14), 1688-1695. doi:10.1016/j.vaccine.2016.02.028

DOI
10.1016/j.vaccine.2016.02.028
Journal article

Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis

Saint, G. L., Smyth, R., Flanagan, B. F., & McNamara, P. S. (2016). Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 193. Retrieved from https://www.webofscience.com/

Conference Paper

Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil

Fawkner-Corbett, D. W., Khoo, S. K., Duarte, C. M., Bezerra, P. G. M., Bochkov, Y. A., Gern, J. E., . . . McNamara, P. S. (2016). Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil. JOURNAL OF MEDICAL VIROLOGY, 88(1), 58-63. doi:10.1002/jmv.24300

DOI
10.1002/jmv.24300
Journal article

2015

Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial?

Gaillard, E. A., McNamara, P. S., Murray, C. S., Pavord, I. D., & Shields, M. D. (2015). Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial?. CLINICAL AND EXPERIMENTAL ALLERGY, 45(9), 1384-1395. doi:10.1111/cea.12535

DOI
10.1111/cea.12535
Journal article

Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review

Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Dixon, S., . . . Cross, E. (2015). Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review. HEALTH TECHNOLOGY ASSESSMENT, 19(66), 1-+. doi:10.3310/hta19660

DOI
10.3310/hta19660
Journal article

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

Habibi, M. S., Jozwik, A., Makris, S., Dunning, J., Paras, A., The Mechanisms of Severe Acute Influenza Consortium Investigators., . . . Chiu, C. (2015). Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(9), 1040-1049. doi:10.1164/rccm.201412-2256OC

DOI
10.1164/rccm.201412-2256OC
Journal article

An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability

Trinick, R. E., Bunni, L., Thorburn, K., Hackett, A. P., Dalzell, M., & McNamara, P. S. (2015). An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability. PLOS ONE, 10(4). doi:10.1371/journal.pone.0124627

DOI
10.1371/journal.pone.0124627
Journal article

2014

SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis

Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Cooper, C. L., . . . Team, S. A. B. R. E. S. (2014). SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. THORAX, 69(12), 1105-1112. doi:10.1136/thoraxjnl-2014-205953

DOI
10.1136/thoraxjnl-2014-205953
Journal article

Turnover of strains and intraclonal variation amongst <i>Pseudomonas aeruginosa</i> isolates from paediatric CF patients

Hall, A. J., Fothergill, J. L., McNamara, P. S., Southern, K. W., & Winstanley, C. (2014). Turnover of strains and intraclonal variation amongst <i>Pseudomonas aeruginosa</i> isolates from paediatric CF patients. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 80(4), 324-326. doi:10.1016/j.diagmicrobio.2014.09.007

DOI
10.1016/j.diagmicrobio.2014.09.007
Journal article

Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol

van Miert, C., Abbott, J., Verheoff, F., Lane, S., Carter, B., & McNamara, P. (2014). Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol. JOURNAL OF ADVANCED NURSING, 70(10), 2353-2362. doi:10.1111/jan.12387

DOI
10.1111/jan.12387
Journal article

Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens

Lees, E., Carrol, E., Gerrard, C., Hardiman, F., Howel, G., Timmis, A., . . . McNamara, P. (2014). Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens. BMC Infectious Diseases, 14. doi:10.1186/1471-2334-14-343

DOI
10.1186/1471-2334-14-343
Journal article

THE B LYMPHOCYTE DIFFERENTIATION FACTOR (BAFF) IS EXPRESSED IN THE AIRWAYS OF CHILDREN WITH CF AND IN LUNGS OF MICE INFECTED WITH PSEUDOMONAS AERUGINOSA

Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014). THE B LYMPHOCYTE DIFFERENTIATION FACTOR (BAFF) IS EXPRESSED IN THE AIRWAYS OF CHILDREN WITH CF AND IN LUNGS OF MICE INFECTED WITH PSEUDOMONAS AERUGINOSA. PLoS One, 9(5). doi:10.1371/journal.pone.0095892.

DOI
10.1371/journal.pone.0095892.
Journal article

Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage

Gray, C., Ahmed, M. S., Mubarak, A., Kasbekar, A. V., Derbyshire, S., McCormick, M. S., . . . Zhang, Q. (2014). Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage. MUCOSAL IMMUNOLOGY, 7(3), 705-717. doi:10.1038/mi.2013.89

DOI
10.1038/mi.2013.89
Journal article

Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection

Flanagan, B., McFarlane, A., Al-Turaiki, W., Fitch, P., Slupsky, J., McNamara, P. S., & Schwarze, J. (2014). Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/

Conference Paper

Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria

Bezerra, P. G. D. M., Duarte, M. M. B., McNamara, P. S., Britto, M. A. D., Rose, K., Cuevas, L. E., . . . Correia, J. D. B. (2014). Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/

Conference Paper

Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus

Duarte, M. M. B., McNamara, P. S., Bezerra, P. G. D. M., Britto, M. A. D., Cuevas, L. E., Rose, K., . . . Correia, J. D. B. (2014). Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/

Conference Paper

2013

Respiratory Viruses and Atypical Bacteria

McNamara, P. S., & Van Doorn, H. R. (2014). Respiratory Viruses and Atypical Bacteria. In Manson's Tropical Infectious Diseases (pp. 215-224.e2). Elsevier. doi:10.1016/b978-0-7020-5101-2.00020-0

DOI
10.1016/b978-0-7020-5101-2.00020-0
Chapter

Comparison of real time diagnostic chemistries to detect <i>Pseudomonas aeruginosa</i> in respiratory samples from cystic fibrosis patients

Fothergill, J. L., Ledson, M. J., Walshaw, M. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Comparison of real time diagnostic chemistries to detect <i>Pseudomonas aeruginosa</i> in respiratory samples from cystic fibrosis patients. JOURNAL OF CYSTIC FIBROSIS, 12(6), 675-681. doi:10.1016/j.jcf.2013.04.007

DOI
10.1016/j.jcf.2013.04.007
Journal article

Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time

Ball, R., Southern, K. W., McCormack, P., Duff, A. J. A., Brownlee, K. G., & McNamara, P. S. (2013). Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time. JOURNAL OF CYSTIC FIBROSIS, 12(5), 440-444. doi:10.1016/j.jcf.2012.12.012

DOI
10.1016/j.jcf.2012.12.012
Journal article

Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses

Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses. JOURNAL OF VIROLOGY, 87(10), 5331-5339. doi:10.1128/JVI.03547-12

DOI
10.1128/JVI.03547-12
Journal article

Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses.

Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses.. Journal of virology, 87(10), 5331-5339. doi:10.1128/jvi.03547-12

DOI
10.1128/jvi.03547-12
Journal article

Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of <i>Pseudomonas aeruginosa</i>

Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of <i>Pseudomonas aeruginosa</i>. JOURNAL OF MEDICAL MICROBIOLOGY, 62, 208-216. doi:10.1099/jmm.0.048272-0

DOI
10.1099/jmm.0.048272-0
Journal article

Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa.

Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa.. Journal of medical microbiology, 62(Pt 2), 208-216. doi:10.1099/jmm.0.048272-0

DOI
10.1099/jmm.0.048272-0
Journal article

After a long wait, two arrive, one after the other!

Southern, K. W., McCormack, P., & McNamara, P. S. (2013). After a long wait, two arrive, one after the other!. THORAX, 68(4), 311-312. doi:10.1136/thoraxjnl-2012-202891

DOI
10.1136/thoraxjnl-2012-202891
Journal article

Induction of Th17 in nasopharynx-associated lymphoid tissue by pneumococcus and the effect of IL-21 and IL-15

Mubarak, A. S., Kasbekar, A., McCormick, M., Beer, H., Cunliffe, N., McNamara, P. S., & Zhang, Q. (2013). Induction of Th17 in nasopharynx-associated lymphoid tissue by pneumococcus and the effect of IL-21 and IL-15. In IMMUNOLOGY Vol. 140 (pp. 105). Retrieved from https://www.webofscience.com/

Conference Paper

Investigating the mechanism of interaction between neutrophils and virus in Respiratory Syncytial Virus (RSV) disease

Saint, G. L., Flanagan, B. F., McNamara, P. S., & Smyth, R. L. (2013). Investigating the mechanism of interaction between neutrophils and virus in Respiratory Syncytial Virus (RSV) disease. In IMMUNOLOGY Vol. 140 (pp. 83-84). Retrieved from https://www.webofscience.com/

Conference Paper

Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF

McNamara, P. S., Fonceca, A. M., Howarth, D., Correia, J. B., Slupsky, J. R., Trinick, R. E., . . . Flanagan, B. F. (2013). Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF. THORAX, 68(1), 76-81. doi:10.1136/thoraxjnl-2012-202288

DOI
10.1136/thoraxjnl-2012-202288
Journal article

2012

New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis

McCormack, P., Southern, K. W., & McNamara, P. S. (2012). New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis. JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 25(6), 307-309. doi:10.1089/jamp.2011.0934

DOI
10.1089/jamp.2011.0934
Journal article

The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil.

Fawkner-Corbett, D. W., Duarte, M. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil.. The Pediatric infectious disease journal, 31(6), 653-655. doi:10.1097/inf.0b013e3182501ff4

DOI
10.1097/inf.0b013e3182501ff4
Journal article

Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis

Trinick, R., Southern, K. W., & McNamara, P. S. (2012). Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis. EUROPEAN RESPIRATORY JOURNAL, 39(4), 899-905. doi:10.1183/09031936.00070311

DOI
10.1183/09031936.00070311
Journal article

IFITM3 restricts the morbidity and mortality associated with influenza

Everitt, A. R., Clare, S., Pertel, T., John, S. P., Wash, R. S., Smith, S. E., . . . Kellam, P. (2012). IFITM3 restricts the morbidity and mortality associated with influenza. NATURE, 484(7395), 519-U146. doi:10.1038/nature10921

DOI
10.1038/nature10921
Journal article

Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection

Fonceca, A. M., Flanagan, B. F., Trinick, R., Smyth, R. L., & McNamara, P. S. (2012). Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection. THORAX, 67(1), 42-48. doi:10.1136/thoraxjnl-2011-200131

DOI
10.1136/thoraxjnl-2011-200131
Journal article

Reflux aspiration in children with neurodisability-a significant problem, but can we measure it?

Trinick, R., Johnston, N., Dalzell, A. M., & McNamara, P. S. (2012). Reflux aspiration in children with neurodisability-a significant problem, but can we measure it?. JOURNAL OF PEDIATRIC SURGERY, 47(2), 291-298. doi:10.1016/j.jpedsurg.2011.11.019

DOI
10.1016/j.jpedsurg.2011.11.019
Journal article

THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL

Fawkner-Corbett, D. W., Duarte, M. D. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 31(6), 653-655. doi:10.1097/INF.0b013e3182501ff4

DOI
10.1097/INF.0b013e3182501ff4
Journal article

2011

A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis

McCormack, P., McNamara, P. S., & Southern, K. W. (2011). A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 10(5), 343-349. doi:10.1016/j.jcf.2011.04.006

DOI
10.1016/j.jcf.2011.04.006
Journal article

Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization

Zhang, Q., Leong, S. C., McNamara, P. S., Mubarak, A., Malley, R., & Finn, A. (2011). Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization. PLOS PATHOGENS, 7(8). doi:10.1371/journal.ppat.1002175

DOI
10.1371/journal.ppat.1002175
Journal article

Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years

Bezerra, P. G. M., Britto, M. C. A., Correia, J. B., Duarte, M. D. C. M. B., Fonceca, A. M., Rose, K., . . . McNamara, P. S. (2011). Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years. PLOS ONE, 6(4). doi:10.1371/journal.pone.0018928

DOI
10.1371/journal.pone.0018928
Journal article

Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains.

Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2011). Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains.. Journal of Cystic Fibrosis, 10 (S1, S32.

Journal article

2010

Microarray genotyping of Pseudomonas aeruginosa isolates from CF units

Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2010). Microarray genotyping of Pseudomonas aeruginosa isolates from CF units. Journal of Cystic Fibrosis, 9, S30. doi:10.1016/s1569-1993(10)60115-4

DOI
10.1016/s1569-1993(10)60115-4
Journal article

2009

Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis

McNamara, P. S., McCormack, P., McDonald, A. J., Heaf, L., & Southern, K. W. (2009). Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 8(4), 258-263. doi:10.1016/j.jcf.2009.04.006

DOI
10.1016/j.jcf.2009.04.006
Journal article

A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic.

Morris, D., Fallon, L., Heaf, L., Burrows, E. F., Wallace, H., McNamara, P. S., . . . Southern, K. W. (2009). A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic.. Ped Pulmonol, 32, 325.

Journal article

2008

Comparison of techniques for obtaining lower airway epithelial cells from children

McNamara, P. S., Kicic, A., Sutanto, E. N., Stevens, P. T., & Stick, S. M. (2008). Comparison of techniques for obtaining lower airway epithelial cells from children. EUROPEAN RESPIRATORY JOURNAL, 32(3), 763-768. doi:10.1183/09031936.00162507

DOI
10.1183/09031936.00162507
Journal article

2007

Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis

McNamara, P. S., Flanagan, B. F., Smyth, R. L., & Hart, C. A. (2007). Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis. PEDIATRIC PULMONOLOGY, 42(8), 740-743. doi:10.1002/ppul.20649

DOI
10.1002/ppul.20649
Journal article

2005

Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease

McNamara, P. S., & Smyth, R. L. (2005). Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease. DRUG NEWS & PERSPECTIVES, 18(10), 615-621. doi:10.1358/dnp.2005.18.10.959575

DOI
10.1358/dnp.2005.18.10.959575
Journal article

Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis

McNamara, P. S., Flanagan, B. F., Hart, C. A., & Smyth, R. L. (2005). Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(8), 1225-1232. doi:10.1086/428855

DOI
10.1086/428855
Journal article

Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis

Semple, M. G., Cowell, A., Dove, W., Greensill, J., McNamara, P. S., Halfhide, C., . . . Hart, C. A. (2005). Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(3), 382-386. doi:10.1086/426457

DOI
10.1086/426457
Journal article

2004

Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis

McNamara, P. S., Flanagan, B. F., Baldwin, L. M., Newland, P., Hart, C. A., & Smyth, R. L. (2004). Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis. LANCET, 363(9414), 1031-1037. doi:10.1016/S0140-6736(04)15838-8

DOI
10.1016/S0140-6736(04)15838-8
Journal article

Cytokines in severe Respiratory Syncytial Virus bronchiolitis

McNamara, P. S. (2004). Cytokines in severe Respiratory Syncytial Virus bronchiolitis. (PhD Thesis, The University of Liverpool).

Thesis / Dissertation

Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis

McNamara, P. S., Flanagan, B. F., Selby, A. M., Hart, C. A., & Smyth, R. L. (2004). Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis. EUROPEAN RESPIRATORY JOURNAL, 23(1), 106-112. doi:10.1183/09031936.03.00048103

DOI
10.1183/09031936.03.00048103
Journal article

2003

Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis

McNamara, P. S., Ritson, P., Selby, A., Hart, C. A., & Smyth, R. L. (2003). Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis. ARCHIVES OF DISEASE IN CHILDHOOD, 88(10), 922-926. doi:10.1136/adc.88.10.922

DOI
10.1136/adc.88.10.922
Journal article

Human metapneumovirus in severe respiratory syncytial virus bronchiolitis

Greensill, J., McNamara, P. S., Dove, W., Flanagan, B., Smyth, R. L., & Hart, C. A. (2003). Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. EMERGING INFECTIOUS DISEASES, 9(3), 372-375. doi:10.3201/eid0903.020289

DOI
10.3201/eid0903.020289
Journal article

2002

A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children

Powell, C. V. E., McNamara, P., Solis, A., & Shaw, N. J. (2002). A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children. ARCHIVES OF DISEASE IN CHILDHOOD, 87(5), 376-379. doi:10.1136/adc.87.5.376

DOI
10.1136/adc.87.5.376
Journal article

The pathogenesis of respiratory syncytial virus disease in childhood

McNamara, P. S., & Smyth, R. L. (2002). The pathogenesis of respiratory syncytial virus disease in childhood. BRITISH MEDICAL BULLETIN, 61, 13-28. doi:10.1093/bmb/61.1.13

DOI
10.1093/bmb/61.1.13
Journal article

2001

Headache and abdominal pain

McNamara, P. S., Mallucci, C. L., & Appleton, R. T. (2001). Headache and abdominal pain. LANCET, 357(9260), 930. doi:10.1016/S0140-6736(00)04215-X

DOI
10.1016/S0140-6736(00)04215-X
Journal article