Research
Galectins in cancer development, progression and metastasis
Translational development of galectin-targeted novel therapeutic agents
Functional significance of cellular glycosylation changes in cancer development and progression
Research grants
Investigating the impact of protein O-glycosylation changes on EGFR activation, signalling and EGFRtargeted cancer therapies
ROYAL SOCIETY
March 2021 - March 2024
Research Support Fees for Muhammed Negedu
TERTIARY EDUCATION TRUST FUND (NIGERIA)
December 2019 - November 2023
The role of MUC1 in anoikis (suspension-induced apoptosis) of human epithelial calls. Biomedical vacation scholarship for Tony Lu. Vacation Scholarship
WELLCOME TRUST (UK)
June 2016 - July 2016
A pilot IBD biomarker study: analysis of serum levels of four proteins in IBD patients and healthy people
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
April 2015 - March 2016
Mucosa-associated bacteria and human colon cancer.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
October 2005 - September 2007
Studies to characterise the intracellular ligands for the anti-proliferative mushroom lectin in colon cancer cells.
NORTH WEST CANCER RESEARCH FUND
June 1999 - June 2002
Characterization of the endothelial cell surface molecule(s) responsible for galectin-3-induced secretion of metastasis-promoting cytokines
NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)
July 2014 - March 2017
Identification and functional characterization of the jacalin-binding cell membrane protein that regulates tyrosine phosphorylation of tumour suppressor PHAPI/pp32.
NORTH WEST CANCER RESEARCH FUND
October 2006 - September 2009
The role of galectin-3-MUC1 interaction in epithelial cancer cell adhesion.
ROYAL SOCIETY (CHARITABLE)
September 2006 - August 2007
In vitro characterization of circulating galectin-3-induced cancer cell adhesion to endothelium.
CANCER RESEARCH UK (UK)
September 2006 - August 2010
Screening the NIH small molecule repository for galectin-3 inhibitors: A pilot study for identification of novel therapeutic leads for cancer treatment
CANCER RESEARCH UK (UK)
July 2010 - June 2011
Investigation into the mechanisms by which the galactose-binding lectin in mushrooms affects proliferation in colon cancer cells.
WORLD CANCER RESEARCH FUND (UK)
December 1999 - November 2002
Tumour suppressing activity of Sclerotium rolfsii lectin on colon cancer
UK-INDIA EDUCATION AND RESEARCH INITIATIVE (UK)
January 2009 - December 2012
The cancer-associated MUC1 and MUC1-galectin interactions in cancer endothelial adhesion and extra-vasation
NORTH WEST CANCER RESEARCH FUND
February 2008 - January 2011
Research collaborations
Professor Jonathan Rhodes
GI cancer
Professor Mark Pritchard
animal models, joint PhD supervision
Dr. Carrie Duckworth
joint PhD supervision
Dr Sreedhar Subramanian
IBD
Dr. Mark Morgan
Joint PhD supervision
Dr. John Hilkens
Netherlands Cancer Institute
MUC1 and cancer
Professor Lu-Yun Lian
Structural biology
Professor Jeremy Turnbull
Heparin
Professor Hans Wandall
University of Copenhagen
Glycan analysis
Dr. Edwin Yates
Joint PhD supervision
Professor Shashikala Inamdar
Karnatak University, India
Joint UK-India Education and Research Initiative (UKIERI) award