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Lesley Iwanejko

Dr Lesley Iwanejko
PhD GDL BVC PGCertHE SFHEA

Contact

Iwanejko@liverpool.ac.uk

https://www.liverpool.ac.uk/literature-and-science/

+44 (0)151 794 4242

+44 (0)151 794 9078

+44 (0)151 795 0381

Publications

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2022

Altered oxidative DNA damage repair systems in muscles of old mice: role in the age-related increase in muscle production of cytokines/chemokines

Kumiscia, K., Shigdar, S., Owen, E., Staunton, C. A., Proctor, C. J., Jackson, M. J., . . . McArdle, A. (2022). Altered oxidative DNA damage repair systems in muscles of old mice: role in the age-related increase in muscle production of cytokines/chemokines. FASEB JOURNAL, 36. doi:10.1096/fasebj.2022.36.S1.R4404

DOI
10.1096/fasebj.2022.36.S1.R4404
Journal article

2021

Development of age-related loss of muscle mass and function - role of oxidative DNA damage repair systems

Kumiscia, K., Shigdar, S., Proctor, C., Shanley, D., Owen, E., Staunton, C., . . . McArdle, A. (2021). Development of age-related loss of muscle mass and function - role of oxidative DNA damage repair systems. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 165. doi:10.1016/j.freeradbiomed.2020.12.339

DOI
10.1016/j.freeradbiomed.2020.12.339
Conference Paper

Development of age-related loss of muscle mass and function – role of oxidative DNA damage repair systems

Kumiscia, K., Shigdar, S., Proctor, C., Shanley, D., Owen, E., Staunton, C., . . . McArdle, A. (2021). Development of age-related loss of muscle mass and function – role of oxidative DNA damage repair systems. Free Radical Biology and Medicine, 165, 30-31. doi:10.1016/j.freeradbiomed.2020.12.335

DOI
10.1016/j.freeradbiomed.2020.12.335
Journal article

2020

Role of 8-oxoG repair in the development of age-related loss of muscle mass and function

Kumiscia, K., McArdle, A., & Iwanejko, L. (2020). Role of 8-oxoG repair in the development of age-related loss of muscle mass and function. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 159 (pp. S43-S44). doi:10.1016/j.freeradbiomed.2020.10.123

DOI
10.1016/j.freeradbiomed.2020.10.123
Conference Paper

2018

17-(Allylamino)-17demethoxygeldanamycin reduces Endoplasmic Reticulum (ER) stress-induced mitochondrial dysfunction in C2C12 myotubes

DOI
10.1101/350702
Preprint

2016

Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression

Goljanek-Whysall, K., Iwanejko, L. A., Vasilaki, A., Pekovic-Vaughan, V., & McDonagh, B. (2016). Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression. MAMMALIAN GENOME, 27(7-8), 341-357. doi:10.1007/s00335-016-9643-x

DOI
10.1007/s00335-016-9643-x
Journal article

FEASIBILITY STUDY OF VOLATILE ORGANIC COMPOUNDS IN CONSTIPATION IN PARKINSON'S DISEASE

Qureshi, S., Bond, A., Iwanejko, L., & Probert, C. (2016). FEASIBILITY STUDY OF VOLATILE ORGANIC COMPOUNDS IN CONSTIPATION IN PARKINSON'S DISEASE. In GUT Vol. 65 (pp. A125-A126). doi:10.1136/gutjnl-2016-312388.224

DOI
10.1136/gutjnl-2016-312388.224
Conference Paper

2014

Glycosylated yellow laccases of the basidiomycete Stropharia aeruginosa

Daroch, M., Houghton, C. A., Moore, J. K., Wilkinson, M. C., Carnell, A. J., Bates, A. D., & Iwanejko, L. A. (2014). Glycosylated yellow laccases of the basidiomycete Stropharia aeruginosa. Enzyme and Microbial Techenology, 58-59, 1-7. doi:10.1016/j.enzmictec.2014.02.003

DOI
10.1016/j.enzmictec.2014.02.003
Journal article

Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle

Cobley, J. N., Sakellariou, G. K., Owens, D. J., Murray, S., Waldron, S., Gregson, W., . . . Close, G. L. (2014). Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle. Free Radical Biology and Medicine, 70, 23-32. doi:10.1016/j.freeradbiomed.2014.02.004

DOI
10.1016/j.freeradbiomed.2014.02.004
Journal article

2013

Purification, characterisation and expression in Saccharomyces cerevisiae of LipG7 an enantioselective, cold-adapted lipase from the Antarctic filamentous fungus Geomyces sp. P7 with unusual thermostability characteristics.

Florczak, T., Daroch, M., Wilkinson, M. C., Białkowska, A., Bates, A. D., Turkiewicz, M., & Iwanejko, L. A. (2013). Purification, characterisation and expression in Saccharomyces cerevisiae of LipG7 an enantioselective, cold-adapted lipase from the Antarctic filamentous fungus Geomyces sp. P7 with unusual thermostability characteristics.. Enzyme and microbial technology, 53(1), 18-24. doi:10.1016/j.enzmictec.2013.03.021

DOI
10.1016/j.enzmictec.2013.03.021
Journal article

2012

Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine †

Bhamra, I., Compagnone-Post, P., O’Neil, I. A., Iwanejko, L. A., Bates, A. D., & Cosstick, R. (2012). Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine †. Nucleic Acids Research, 40(21), 11126-11138. doi:10.1093/nar/gks799

DOI
10.1093/nar/gks799
Journal article

2006

Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age

Vasilaki, A., McArdle, F., Iwanejko, L. M., & McArdle, A. (2006). Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age. MECHANISMS OF AGEING AND DEVELOPMENT, 127(11), 830-839. doi:10.1016/j.mad.2006.08.004

DOI
10.1016/j.mad.2006.08.004
Journal article

2005

Fact and artefact:: poetry, science, and a few thoughts on Ian!McEwan's <i>Saturday</i>

Rees-Jones, D. (2005). Fact and artefact:: poetry, science, and a few thoughts on Ian!McEwan's <i>Saturday</i>. INTERDISCIPLINARY SCIENCE REVIEWS, 30(4), 331-340. doi:10.1179/030801805X64915

DOI
10.1179/030801805X64915
Journal article

2004

Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice

McArdle, F., Spiers, S., Aldemir, H., Vasilaki, A., Beaver, A., Iwanejko, L., . . . Jackson, M. J. (2004). Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice. JOURNAL OF PHYSIOLOGY-LONDON, 561(1), 233-244. doi:10.1113/jphysiol.2004.069914

DOI
10.1113/jphysiol.2004.069914
Journal article

2003

Skeletal muscles of aged male mice fail to adapt following contractile activity

Vasilaki, A., Iwanejko, L., McArdle, F., Broome, C. S., Jackson, M. J., & McArdle, A. (2003). Skeletal muscles of aged male mice fail to adapt following contractile activity. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 455-456. doi:10.1042/BST0310455

DOI
10.1042/BST0310455
Journal article

Age-related hotspots of oxidative damage in yeast genomic and mitochondrial DNA

Cheng, L., Parry, D., Strike, P., & Iwanejko, L. (2003). Age-related hotspots of oxidative damage in yeast genomic and mitochondrial DNA. Yeast, 20, S306.

Journal article

2002

Adaptation in skeletal muscle of mice following exercise: The effect of age and gender

Vasilaki, A., Iwanejko, L., Jackson, M. J., & McArdle, A. (2002). Adaptation in skeletal muscle of mice following exercise: The effect of age and gender. FASEB JOURNAL, 16(4), A392. Retrieved from https://www.webofscience.com/

Journal article

Mechanisms responsible for attenuated adaptive responses in skeletal muscle of aged mice following contractile activity

Vasilaki, A., Iwanejko, L., McArdle, F., Jackson, M. J., & McArdle, A. (2002). Mechanisms responsible for attenuated adaptive responses in skeletal muscle of aged mice following contractile activity. JOURNAL OF PHYSIOLOGY-LONDON, 543, 100P-101P. Retrieved from https://www.webofscience.com/

Journal article

1999

Disruption and functional analysis of seven ORFs on chromosome IV: YDL057w, YDL012c, YDL010w, YDL009c, YDL008w (APC11), YDL005c (MED2) and YDL003w (MCD1).

Smith, K. N., Iwanejko, L., Loeillet, S., Fabre, F., & Nicolas, A. (1999). Disruption and functional analysis of seven ORFs on chromosome IV: YDL057w, YDL012c, YDL010w, YDL009c, YDL008w (APC11), YDL005c (MED2) and YDL003w (MCD1).. Yeast (Chichester, England), 15(12), 1255-1267. doi:3.0.co;2-l">10.1002/(sici)1097-0061(19990915)15:12<1255::aid-yea451>3.0.co;2-l

DOI
10.1002/(sici)1097-0061(19990915)15:12<1255::aid-yea451>3.0.co;2-l
Journal article

Cloning and characterisation of the sagA gene of Aspergillus nidulans: a gene which affects sensitivity to DNA-damaging agents.

Jones, G. W., Hooley, P., Farrington, S. M., Shawcross, S. G., Iwanejko, L. A., & Strike, P. (1999). Cloning and characterisation of the sagA gene of Aspergillus nidulans: a gene which affects sensitivity to DNA-damaging agents.. Molecular & general genetics : MGG, 261(2), 251-258. doi:10.1007/s004380050964

DOI
10.1007/s004380050964
Journal article

Disruption and functional analysis of six ORFs on chromosome XV: YOL117w, YOL115w ( TRF4), YOL114c, YOL112w ( MSB4), YOL111c and YOL072w.

Iwanejko, L., Smith, K. N., Loeillet, S., Nicolas, A., & Fabre, F. (1999). Disruption and functional analysis of six ORFs on chromosome XV: YOL117w, YOL115w ( TRF4), YOL114c, YOL112w ( MSB4), YOL111c and YOL072w.. Yeast (Chichester, England), 15(14), 1529-1539. doi:3.0.co;2-y">10.1002/(sici)1097-0061(199910)15:14<1529::aid-yea457>3.0.co;2-y

DOI
10.1002/(sici)1097-0061(199910)15:14<1529::aid-yea457>3.0.co;2-y
Journal article

1998

Recent advances in DNA repair and recombination.

Iwanejko, L. A., & Jones, N. J. (1998). Recent advances in DNA repair and recombination.. In Mutation research Vol. 408 (pp. 227-236). doi:10.1016/s0921-8777(98)00033-0

DOI
10.1016/s0921-8777(98)00033-0
Conference Paper

1996

Physical analysis of part of band 6q21 harboring a putative tumor suppressor gene and a putative senescence gene.

Morelli, C., Sherratt, T., Greaves, M. J., Iwanejko, L., Trabanelli, C., Rimessi, P., . . . Boyle, J. M. (1996). Physical analysis of part of band 6q21 harboring a putative tumor suppressor gene and a putative senescence gene.. DNA sequence : the journal of DNA sequencing and mapping, 7(1), 43-45. doi:10.3109/10425179609015646

DOI
10.3109/10425179609015646
Journal article

nuvA, an Aspergillus nidulans gene involved in DNA repair and recombination, is a homologue of Saccharomyces cerevisiae RAD18 and Neurospora crassa uvs-2.

Iwanejko, L., Cotton, C., Jones, G., Tomsett, B., & Strike, P. (1996). nuvA, an Aspergillus nidulans gene involved in DNA repair and recombination, is a homologue of Saccharomyces cerevisiae RAD18 and Neurospora crassa uvs-2.. Microbiology (Reading, England), 142 ( Pt 3), 505-515. doi:10.1099/13500872-142-3-505

DOI
10.1099/13500872-142-3-505
Journal article

1994

A complex array of Hpr consensus DNA recognition sequences proximal to the enterotoxin gene in Clostridium perfringens type A.

Brynestad, S., Iwanejko, L. A., Stewart, G. S., & Granum, P. E. (1994). A complex array of Hpr consensus DNA recognition sequences proximal to the enterotoxin gene in Clostridium perfringens type A.. Microbiology (Reading, England), 140 ( Pt 1), 97-104. doi:10.1099/13500872-140-1-97

DOI
10.1099/13500872-140-1-97
Journal article

1989

Cloning in Escherichia coli of the enterotoxin gene from Clostridium perfringens type A.

Iwanejko, L. A., Routledge, M. N., & Stewart, G. S. (1989). Cloning in Escherichia coli of the enterotoxin gene from Clostridium perfringens type A.. Journal of general microbiology, 135(4), 903-909. doi:10.1099/00221287-135-4-903

DOI
10.1099/00221287-135-4-903
Journal article

Analysis of plasmid profiling as a method for rapid differentiation of food-associated Clostridium perfringens strains.

Jones, M. K., Iwanejko, L. A., & Longden, M. S. (1989). Analysis of plasmid profiling as a method for rapid differentiation of food-associated Clostridium perfringens strains.. The Journal of applied bacteriology, 67(3), 243-254. doi:10.1111/j.1365-2672.1989.tb02492.x

DOI
10.1111/j.1365-2672.1989.tb02492.x
Journal article

1988

Cloning in <i>Escherichia coli</i> of a DNA sequence with translational fidelity to the known protein sequence for <i>Clostridium perfringens</i> sporulation specific enterotoxin

IWANEJKO, L. A., & STEWART, G. S. A. B. (1988). Cloning in <i>Escherichia coli</i> of a DNA sequence with translational fidelity to the known protein sequence for <i>Clostridium perfringens</i> sporulation specific enterotoxin. Biochemical Society Transactions, 16(6), 1069. doi:10.1042/bst0161069

DOI
10.1042/bst0161069
Journal article