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Research

Research Interest 1

Population PK-PD modelling of infectious disease medications, namely HIV and TB at both pre-clinical & clinical stages but also in other disease areas. Work also includes optimisation of dosing strategies in special populations and investigation of drug-drug interactions. Extensively involved in data analysis of clinical trials

Research collaborations

Gerjo de Knegt/Jurriaan de Steenwinkel

Erasmus MC

Modelling CFU count in Mtb mouse model

Dr Marta Boffito

St Stephen's AIDS Trust, Chelsea & Westminster Hospital

Population PK modelling - various HIV drugs

Dr Max von Kleist

Freie Universität Berlin

Providing PK simulations to feed into mathematica simulations of pre-exposure prophylaxis (PrEP) for various HIV drugs

Dr Dan Wooton

Population modelling of CAPsym data (pneumonia symptoms score)

Dr Sean Emery/Dr Dianne Carey

Kirby Institute, UNSW Australia

Population PK modelling - dose reduction of efavirenz

Dr Alan Winston

Imperial College, London

Population PK modelling - various HIV drugs