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Em P James Gallagher
B.Sc., M.Sc., Ph.D.

Professor
Musculoskeletal & Ageing Science
Part of
Institute of Life Course & Medical Sciences
Faculty of Health and Life Sciences

Contact

J.A.Gallagher@liverpool.ac.uk

http://www.liv.ac.uk/hacb

Publications

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2022

Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria.

Ranganath, L. R., Hughes, A. T., Davison, A. S., Khedr, M., Olsson, B., Rudebeck, M., . . . Milan, A. M. (2022). Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria.. Molecular genetics and metabolism, S1096-7192(22)00325-0. doi:10.1016/j.ymgme.2022.05.006

DOI
10.1016/j.ymgme.2022.05.006
Journal article

Altered bone metabolism in the rare inherited disease alkaptonuria

Norman, B. P., Hughes, J. H., Sutherland, H., Wilson, P. J., Ranganath, L. R., Bou-Gharios, G., & Gallagher, J. A. (2022). Altered bone metabolism in the rare inherited disease alkaptonuria. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A3). Retrieved from https://www.webofscience.com/

Conference Paper

Altered bone metabolism in the rare inherited disease alkaptonuria

Norman, B. P., Hughes, J. H., Sutherland, H., Wilson, P. J., Ranganath, L. R., Bou-Gharios, G., & Gallagher, J. A. (2022). Altered bone metabolism in the rare inherited disease alkaptonuria. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A8-A9). Retrieved from https://www.webofscience.com/

Conference Paper

Distribution of ochronotic pigment in the connective tissues of an alkaptonuria cadaver

Hughes, J. H., Thomas, N. P., Rothwell, P. D., Tierney, C. M., Ranganath, L. R., Gallagher, J. A., & Bond, A. P. (2022). Distribution of ochronotic pigment in the connective tissues of an alkaptonuria cadaver. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A8). Retrieved from https://www.webofscience.com/

Conference Paper

2021

Osteoarthritis-Slow but Steady Steps Forward

Gallagher, J. A. (2021). Osteoarthritis-Slow but Steady Steps Forward. CALCIFIED TISSUE INTERNATIONAL, 109(3), 241-242. doi:10.1007/s00223-021-00876-7

DOI
10.1007/s00223-021-00876-7
Journal article

Characterising the arthroplasty in spondyloarthropathy in a large cohort of eighty-seven patients with alkaptonuria

Ranganath, L. R., Gallagher, J. A., Davidson, J., & Vinjamuri, S. (2021). Characterising the arthroplasty in spondyloarthropathy in a large cohort of eighty-seven patients with alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 44(3), 656-665. doi:10.1002/jimd.12340

DOI
10.1002/jimd.12340
Journal article

Characterizing the alkaptonuria joint and spine phenotype and assessing the effect of homogentisic acid lowering therapy in a large cohort of 87 patients

Ranganath, L. R., Khedr, M., Vinjamuri, S., & Gallagher, J. A. (2021). Characterizing the alkaptonuria joint and spine phenotype and assessing the effect of homogentisic acid lowering therapy in a large cohort of 87 patients. JOURNAL OF INHERITED METABOLIC DISEASE, 44(3), 666-676. doi:10.1002/jimd.12363

DOI
10.1002/jimd.12363
Journal article

Frequency, diagnosis, pathogenesis and management of osteoporosis in alkaptonuria: data analysis from the UK National Alkaptonuria Centre

Ranganath, L. R., Khedr, M., Vinjamuri, S., & Gallagher, J. A. (2021). Frequency, diagnosis, pathogenesis and management of osteoporosis in alkaptonuria: data analysis from the UK National Alkaptonuria Centre. OSTEOPOROSIS INTERNATIONAL, 32(5), 927-938. doi:10.1007/s00198-020-05671-y

DOI
10.1007/s00198-020-05671-y
Journal article

Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2-dioxygenase deficiency in the liver is responsible for homogentisic acid-derived ochronotic pigmentation.

Wilson, P. J. M., Ranganath, L. R., Bou-Gharios, G., Gallagher, J. A., & Hughes, J. H. (2021). Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2-dioxygenase deficiency in the liver is responsible for homogentisic acid-derived ochronotic pigmentation.. JIMD reports, 58(1), 52-60. doi:10.1002/jmd2.12184

DOI
10.1002/jmd2.12184
Journal article

Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces

Hughes, J. H., Keenan, C. M., Sutherland, H., Edwards, H. R., Wilson, P. J. M., Ranganath, L. R., . . . Gallagher, J. A. (n.d.). Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces. Calcified Tissue International. doi:10.1007/s00223-020-00764-6

DOI
10.1007/s00223-020-00764-6
Journal article

The anatomical distribution of ochronotic pigment in alkaptonuric mice reveals that ageing and mechanical loading make collagen susceptible to chemical attack

Hughes, J. H., Keenan, C. M., Sutherland, H., Edwards, H. R., Ranganath, L. R., Bou-Gharios, G., & Gallagher, J. A. (2021). The anatomical distribution of ochronotic pigment in alkaptonuric mice reveals that ageing and mechanical loading make collagen susceptible to chemical attack. In JOURNAL OF ANATOMY Vol. 238 (pp. 200). Retrieved from https://www.webofscience.com/

Conference Paper

2020

Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial

Ranganath, L. R., Psarelli, E. E., Arnoux, J. -B., Braconi, D., Briggs, M., Broijersen, A., . . . Gallagher, J. A. (2020). Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial. The Lancet Diabetes and Endocrinology, 8(9), 762-772. doi:10.1016/S2213-8587(20)30228-X

DOI
10.1016/S2213-8587(20)30228-X
Journal article

Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage

Chow, W. Y., Norman, B. P., Roberts, N. B., Ranganath, L. R., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(29), 11937-11942. doi:10.1002/anie.202000618

DOI
10.1002/anie.202000618
Journal article

Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria

Ranganath, L. R., Milan, A. M., Hughes, A. T., Khedr, M., Davison, A. S., Shweihdi, E., . . . Gallagher, J. A. (2020). Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43(4), 737-747. doi:10.1002/jimd.12181

DOI
10.1002/jimd.12181
Journal article

A COMPARISON BETWEEN HIGH DENSITY MINERALISED PROTRUSIONS IDENTIFIED IN THE KNEES OF CADAVERS AND IN PATIENTS OF THE OSTEOARTHRITIS INITIATIVE

Thomas, N. P., Jeffery, N., Adams, V., Ranganath, L. R., Boyde, A., & Gallagher, J. A. (2020). A COMPARISON BETWEEN HIGH DENSITY MINERALISED PROTRUSIONS IDENTIFIED IN THE KNEES OF CADAVERS AND IN PATIENTS OF THE OSTEOARTHRITIS INITIATIVE. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S51-S52). Retrieved from https://www.webofscience.com/

Conference Paper

WHAT RARE DISEASES CAN TELL US ABOUT OA

Gallagher, J. A. (2020). WHAT RARE DISEASES CAN TELL US ABOUT OA. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S15). Retrieved from https://www.webofscience.com/

Conference Paper

Identifying and quantification of cardiovascular calcification by 18F-NaF PET/CT in alkaptonuria patients

Alawadhi, E., Vinjamuri, S., Gallagher, J. A., Lakshminarayan, R., & Dillon, J. (2020). Identifying and quantification of cardiovascular calcification by 18F-NaF PET/CT in alkaptonuria patients. In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Vol. 47 (pp. S143-S144). Retrieved from https://www.webofscience.com/

Conference Paper

2019

Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis

Taylor, A. M., Jenks, D. D., Kammath, V. D., Norman, B. P., Dillon, J. P., Gallagher, J. A., . . . Kerns, J. G. (2019). Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis. OSTEOARTHRITIS AND CARTILAGE, 27(8), 1244-1251. doi:10.1016/j.joca.2019.04.012

DOI
10.1016/j.joca.2019.04.012
Journal article

Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.

Davison, A. S., Strittmatter, N., Sutherland, H., Hughes, A. T., Hughes, J., Bou-Gharios, G., . . . Gallagher, J. A. (2019). Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging.. Metabolomics : Official journal of the Metabolomic Society, 15(5), 68. doi:10.1007/s11306-019-1531-4

DOI
10.1007/s11306-019-1531-4
Journal article

EXTRACELLULAR CHEMICAL PROFILING BY LC-QTOF-MS IDENTIFIES NOVEL BONE RESORPTION MARKERS FOR MONITORING PROGRESSION OF OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA

Norman, B. P., Dillon, J. P., Wilson, P. J., Davison, A. S., Milan, A. M., Ross, G. R., . . . Gallagher, J. A. (2019). EXTRACELLULAR CHEMICAL PROFILING BY LC-QTOF-MS IDENTIFIES NOVEL BONE RESORPTION MARKERS FOR MONITORING PROGRESSION OF OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S181-S182). doi:10.1016/j.joca.2019.02.274

DOI
10.1016/j.joca.2019.02.274
Conference Paper

2018

Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone.

Griffin, R., Psarelli, E. E., Cox, T. F., Khedr, M., Milan, A. M., Davison, A. S., . . . Ranganath, L. R. (2018). Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone.. Data in Brief, 20, 1620-1628. doi:10.1016/j.dib.2018.09.021

DOI
10.1016/j.dib.2018.09.021
Journal article

Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone

Davison, A. S., Harrold, J. A., Hughes, G., Norman, B., Devine, J., Usher, J., . . . Ranganath, L. R. (2018). Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone. Molecular Genetics and Metabolism, 125(1-2), 135-143. doi:10.1016/j.ymgme.2018.07.008

DOI
10.1016/j.ymgme.2018.07.008
Journal article

Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre

Ranganath, L. R., Khedr, M., Milan, A. M., Davison, A. S., Hughes, A. T., Usher, J. L., . . . Gallagher, J. A. (2018). Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre. Molecular genetics and metabolism, 125(1-2), 127-134. doi:10.1016/j.ymgme.2018.07.011

DOI
10.1016/j.ymgme.2018.07.011
Journal article

LONGITUDINAL SURVEY FOR HIGH DENSITY MINERALISED PROTRUSIONS IDENTIFIED BY 3D DESS MRI IN PATIENTS OF THE OSTEOARTHRITIS INITIATIVE

Thomas, N. P., Jeffery, N., Ranganath, L. R., Boyde, A., & Gallagher, J. A. (2018). LONGITUDINAL SURVEY FOR HIGH DENSITY MINERALISED PROTRUSIONS IDENTIFIED BY 3D DESS MRI IN PATIENTS OF THE OSTEOARTHRITIS INITIATIVE. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S467). doi:10.1016/j.joca.2018.02.880

DOI
10.1016/j.joca.2018.02.880
Conference Paper

COMBINED LC-QTOF-MS URINE METABOLOMICS AND 18F-NAF PET IMAGING INDICATES NOVEL COMPOUNDS ASSOCIATED WITH SPINE OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA

Norman, B. P., Taylor, L. F., Davison, A. S., Milan, A. M., Ross, G. A., Roberts, N. B., . . . Gallagher, J. A. (2018). COMBINED LC-QTOF-MS URINE METABOLOMICS AND 18F-NAF PET IMAGING INDICATES NOVEL COMPOUNDS ASSOCIATED WITH SPINE OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S170). doi:10.1016/j.joca.2018.02.369

DOI
10.1016/j.joca.2018.02.369
Conference Paper

DISRUPTION OF COLLAGEN TRIPLE HELIX HYDROGEN BONDING IN OCHRONOTIC HUMAN CARTILAGE IN ALKAPTONURIA OBSERVED BY DYNAMIC NUCLEAR POLARISATION-ENHANCED SOLID-STATE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Norman, B. P., Ying, C. W., Sutherland, H., Wilson, P. J., Roberts, N. B., Duer, M. J., . . . Gallagher, J. A. (2018). DISRUPTION OF COLLAGEN TRIPLE HELIX HYDROGEN BONDING IN OCHRONOTIC HUMAN CARTILAGE IN ALKAPTONURIA OBSERVED BY DYNAMIC NUCLEAR POLARISATION-ENHANCED SOLID-STATE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S99). doi:10.1016/j.joca.2018.02.214

DOI
10.1016/j.joca.2018.02.214
Conference Paper

LASER ABLATION MACHINED SECTIONS PERMIT CORRELATIVE STUDIES OF HDMPS BY X-RAY MICROTOMOGRAPHY, OPTICAL AND SCANNING ELECTRON MICROSCOPY

Boyde, A., Mills, D., Ranganath, L. A., & Gallagher, J. A. (2018). LASER ABLATION MACHINED SECTIONS PERMIT CORRELATIVE STUDIES OF HDMPS BY X-RAY MICROTOMOGRAPHY, OPTICAL AND SCANNING ELECTRON MICROSCOPY. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S74-S75). doi:10.1016/j.joca.2018.02.158

DOI
10.1016/j.joca.2018.02.158
Conference Paper

Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment

Davison, A. S., Norman, B., Milan, A. M., Hughes, A. T., Khedr, M., Rovensky, J., . . . Ranganath, L. R. (2018). Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment. JIMD REPORTS: FOCUS ISSUE: ADULTS AND METABOLISM, VOL 41, 41, 1-10. doi:10.1007/8904_2017_72

DOI
10.1007/8904_2017_72
Journal article

Asymptomatic Corneal Keratopathy Secondary to Hypertyrosinaemia Following Low Dose Nitisinone and a Literature Review of Tyrosine Keratopathy in Alkaptonuria

Khedr, M., Judd, S., Briggs, M. C., Hughes, A. T., Milan, A. M., Stewart, R. M. K., . . . Ranganath, L. R. (2018). Asymptomatic Corneal Keratopathy Secondary to Hypertyrosinaemia Following Low Dose Nitisinone and a Literature Review of Tyrosine Keratopathy in Alkaptonuria. JIMD REPORTS, VOL 40, 40, 31-37. doi:10.1007/8904_2017_62

DOI
10.1007/8904_2017_62
Journal article

The Rare Disease, Alkaptonuria, Reveals New Mechanisms of Joint Destruction, Subchondral Cracking and HDMP Formation, that may be Prevalent in Osteoarthritis

Gallagher, J. A., Thomas, N. P., Jeffery, N., Ranganath, L. R., & Boyde, A. (2018). The Rare Disease, Alkaptonuria, Reveals New Mechanisms of Joint Destruction, Subchondral Cracking and HDMP Formation, that may be Prevalent in Osteoarthritis. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 33 (pp. 245). Retrieved from https://www.webofscience.com/

Conference Paper

2017

The effect of nitisinone on homogentisic acid and tyrosine: a two-year survey of patients attending the National Alkaptonuria Centre, Liverpool

Milan, A. M., Hughes, A. T., Davison, A. S., Devine, J., Usher, J., Curtis, S., . . . Ranganath, L. R. (2017). The effect of nitisinone on homogentisic acid and tyrosine: a two-year survey of patients attending the National Alkaptonuria Centre, Liverpool. Annals of Clinical Biochemistry, 54(3), 323-330. doi:10.1177/0004563217691065

DOI
10.1177/0004563217691065
Journal article

AN INVESTIGATION OF HIGH DENSITY MINERALISED PROTRUSIONS IN HUMAN CADAVERIC KNEES BY MRI AND MICROTOMOGRAPHY

Thomas, N. P., Jeffery, N., van't Hof, R., Adams, V. L., Saers, J., Ranganath, L. R., . . . Gallagher, J. A. (2017). AN INVESTIGATION OF HIGH DENSITY MINERALISED PROTRUSIONS IN HUMAN CADAVERIC KNEES BY MRI AND MICROTOMOGRAPHY. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S253-S254). doi:10.1016/j.joca.2017.02.427

DOI
10.1016/j.joca.2017.02.427
Conference Paper

ANATOMICAL DISTRIBUTION OF 18F PET SIGNAL IN PATIENTS WITH OSTEOARTHROPATHY OF ALKAPTONURIA

Taylor, L. F., Baker, M., Vinjamuri, S., Jeffery, N., Ranganath, L. R., & Gallagher, J. A. (2017). ANATOMICAL DISTRIBUTION OF 18F PET SIGNAL IN PATIENTS WITH OSTEOARTHROPATHY OF ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S401). doi:10.1016/j.joca.2017.02.689

DOI
10.1016/j.joca.2017.02.689
Conference Paper

Defining the properties of an array of -NH2- modified substrates for the induction of a mature osteoblast/osteocyte phenotype from a primary human osteoblast population using controlled nanotopography and surface chemistry

Fawcett, S. A., Curran, J. M., Chen, R., Rhodes, N. P., Murphy, M. F., Wilson, P., . . . Hunt, J. A. (2017). Defining the properties of an array of -NH2- modified substrates for the induction of a mature osteoblast/osteocyte phenotype from a primary human osteoblast population using controlled nanotopography and surface chemistry. Calcified Tissue International, 100(1), 95-106. doi:10.1007/s00223-016-0202-y

DOI
10.1007/s00223-016-0202-y
Journal article

2016

What does the arthropathy of alkaptonuria teach us about disease mechanisms in osteoarthritis and ageing of joints? <i>Lessons from a rare disease</i>

Gallagher, J. A., Ranganath, L. R., & Boyde, A. (2016). What does the arthropathy of alkaptonuria teach us about disease mechanisms in osteoarthritis and ageing of joints? <i>Lessons from a rare disease</i>. RHEUMATOLOGY, 55(7), 1151-1152. doi:10.1093/rheumatology/kev401

DOI
10.1093/rheumatology/kev401
Journal article

Acute fatal metabolic complications in alkaptonuria

Davison, A. S., Milan, A. M., Gallagher, J. A., & Ranganath, L. R. (2016). Acute fatal metabolic complications in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 39(2), 203-210. doi:10.1007/s10545-015-9902-0

DOI
10.1007/s10545-015-9902-0
Journal article

Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury

Varley, I., Greeves, J. P., Sale, C., Friedman, E., Moran, D. S., Yanovich, R., . . . Gallagher, J. A. (2016). Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury. PURINERGIC SIGNALLING, 12(01), 103-113. doi:10.1007/s11302-016-9495-6

DOI
10.1007/s11302-016-9495-6
Journal article

Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

Ranganath, L. R., Milan, A. M., Hughes, A. T., Dutton, J. J., Fitzgerald, R., Briggs, M. C., . . . Rovensky, J. (2016). Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment. Annals of Rheumatic Disease, 75(2), 362-367. doi:10.1136/annrheumdis-2014-206033

DOI
10.1136/annrheumdis-2014-206033
Journal article

Twelve novel <i>HGD</i> gene variants identified in 99 alkaptonuria patients: focus on 'black bone disease' in Italy

Nemethova, M., Radvanszky, J., Kadasi, L., Ascher, D. B., Pires, D. E. V., Blundell, T. L., . . . Zatkova, A. (2016). Twelve novel <i>HGD</i> gene variants identified in 99 alkaptonuria patients: focus on 'black bone disease' in Italy. EUROPEAN JOURNAL OF HUMAN GENETICS, 24(1), 66-72. doi:10.1038/ejhg.2015.60

DOI
10.1038/ejhg.2015.60
Journal article

2015

Progress in Alkaptonuria - are we near to an effective therapy?

Ranganath, L. R., Timmis, O. G., & Gallagher, J. A. (2015). Progress in Alkaptonuria - are we near to an effective therapy?. JOURNAL OF INHERITED METABOLIC DISEASE, 38(5), 787-789. doi:10.1007/s10545-015-9888-7

DOI
10.1007/s10545-015-9888-7
Journal article

Serum markers in alkaptonuria: simultaneous analysis of homogentisic acid, tyrosine and nitisinone by liquid chromatography tandem mass spectrometry

Hughes, A. T., Milan, A. M., Davison, A. S., Christensen, P., Ross, G., Gallagher, J. A., . . . Ranganath, L. R. (2015). Serum markers in alkaptonuria: simultaneous analysis of homogentisic acid, tyrosine and nitisinone by liquid chromatography tandem mass spectrometry. ANNALS OF CLINICAL BIOCHEMISTRY, 52(05), 597-605. doi:10.1177/0004563215571969

DOI
10.1177/0004563215571969
Journal article

Lessons from rare diseases of cartilage and bone

Gallagher, J. A., Ranganath, L. R., & Boyde, A. (2015). Lessons from rare diseases of cartilage and bone. CURRENT OPINION IN PHARMACOLOGY, 22, 107-114. doi:10.1016/j.coph.2015.04.002

DOI
10.1016/j.coph.2015.04.002
Journal article

Musculoskeletal: Are there common targets to prevent age-related changes in muscle, cartilage and bone?

Gallagher, J. A., & Russell, R. G. G. (2015). Musculoskeletal: Are there common targets to prevent age-related changes in muscle, cartilage and bone?. CURRENT OPINION IN PHARMACOLOGY, 22, V-VIII. doi:10.1016/j.coph.2015.05.007

DOI
10.1016/j.coph.2015.05.007
Journal article

Diagnostic tools and strategies for assessing disease progression in Alkaptonuria

Ranganath, L. R., Psarelli, E. E., Cox, T. F., & Gallagher, J. A. (2015). Diagnostic tools and strategies for assessing disease progression in Alkaptonuria. EXPERT OPINION ON ORPHAN DRUGS, 3(6), 705-717. doi:10.1517/21678707.2015.1042859

DOI
10.1517/21678707.2015.1042859
Journal article

ANALYSIS OF CARTILAGE BIOMARKERS OF AGING AND TURNOVER IN THE OSTEOARTHROPATHY OF ALKAPTONURIA

Taylor, A. M., Hsueh, M. -F., Ranganath, L. R., Gallagher, J. A., Catterall, J. B., & Kraus, V. B. (2015). ANALYSIS OF CARTILAGE BIOMARKERS OF AGING AND TURNOVER IN THE OSTEOARTHROPATHY OF ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 23 (pp. A135). doi:10.1016/j.joca.2015.02.867

DOI
10.1016/j.joca.2015.02.867
Conference Paper

Diagnostic tools and strategies for assessing disease progression in Alkaptonuria

Ranganath, L., Psarelli, E., Cox, T., & Gallagher, J. (2015). Diagnostic tools and strategies for assessing disease progression in Alkaptonuria. Expert Opinion in Orphan Drugs, 3(6), 705-717. doi:10.1517/21678707.2015

DOI
10.1517/21678707.2015
Journal article

Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria

Genovese, F., Siebuhr, A. S., Musa, K., Gallagher, J. A., Milan, A. M., Karsdal, M. A., . . . Ranganath, L. R. (2015). Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria. JIMD REPORTS, VOL 24, 24, 29-37. doi:10.1007/8904_2015_430

DOI
10.1007/8904_2015_430
Journal article

Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice

Keenan, C. M., Preston, A. J., Sutherland, H., Wilson, P. J., Psarelli, E. E., Cox, T. F., . . . Gallagher, J. A. (2015). Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice. JIMD REPORTS, VOL 24, 24, 45-50. doi:10.1007/8904_2015_437

DOI
10.1007/8904_2015_437
Journal article

2014

Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle

Vickerton, P., Jarvis, J. C., Gallagher, J. A., Akhtar, R., Sunderland, H., & Jeffery, N. (2014). Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle. Proceedings of the Royal Society B: Biological Sciences, 281(1788). doi:10.1098/rspb.2014.0786

DOI
10.1098/rspb.2014.0786
Journal article

Differential effects of adiponectin in osteoblast-like cells

Pacheco-Pantoja, E. L., Fraser, W. D., Wilson, P., & Gallagher, J. A. (2014). Differential effects of adiponectin in osteoblast-like cells. Journal of Receptors and Signal Transduction, 34(05), 351-360. doi:10.3109/10799893.2014.898658

DOI
10.3109/10799893.2014.898658
Journal article

Urine homogentisic acid and tyrosine: simultaneous analysis by liquid chromatography tandem mass spectrometry.

Hughes, A. T., Milan, A. M., Christensen, P., Ross, G., Davison, A. S., Gallagher, J. A., . . . Ranganath, L. R. (2014). Urine homogentisic acid and tyrosine: simultaneous analysis by liquid chromatography tandem mass spectrometry.. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 963, 106-112. doi:10.1016/j.jchromb.2014.06.002

DOI
10.1016/j.jchromb.2014.06.002
Journal article

IDENTIFICATION OF CONCENTRIC LAMELLAE IN THE ARTICULAR CALCIFIED CARTILAGE OF OSTEOARTHRITIC MICE

Keenan, C. M., Beckett, A., Sutherland, H., Prior, I., Ranganath, L. R., Jarvis, J. C., & Gallagher, J. A. (2014). IDENTIFICATION OF CONCENTRIC LAMELLAE IN THE ARTICULAR CALCIFIED CARTILAGE OF OSTEOARTHRITIC MICE. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S363-S364). doi:10.1016/j.joca.2014.02.673

DOI
10.1016/j.joca.2014.02.673
Conference Paper

RARE SYNDROMES: WHAT THEY TEACH US ABOUT OSTEOARTHRITIS DISEASE MECHANISMS

Gallagher, J. A. (2014). RARE SYNDROMES: WHAT THEY TEACH US ABOUT OSTEOARTHRITIS DISEASE MECHANISMS. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S1). doi:10.1016/j.joca.2014.02.015

DOI
10.1016/j.joca.2014.02.015
Conference Paper

DEVELOPMENT OF OSTEOARTHRITIS IN ALKAPTONURIC MICE

Keenan, C. M., Sutherland, H., Ranganath, L. R., Jarvis, J. C., & Gallagher, J. A. (2014). DEVELOPMENT OF OSTEOARTHRITIS IN ALKAPTONURIC MICE. In RHEUMATOLOGY Vol. 53 (pp. 131). Retrieved from https://www.webofscience.com/

Conference Paper

Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone

Preston, A. J., Keenan, C. M., Sutherland, H., Wilson, P. J., Wlodarski, B., Taylor, A. M., . . . Jarvis, J. C. (2014). Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone. Annals of the Rheumatic Diseases, 73(1), 284-289. doi:10.1136/annrheumdis-2012-202878

DOI
10.1136/annrheumdis-2012-202878
Journal article

Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone

Preston, A. J., Keenan, C. M., Sutherland, H., Wilson, P. J., Wlodarski, B., Taylor, A. M., . . . Jarvis, J. C. (2014). Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone. ANNALS OF THE RHEUMATIC DISEASES, 73(1), 284-289. doi:10.1136/annrheumdis-2012-202878

DOI
10.1136/annrheumdis-2012-202878
Journal article

On fragmenting, densely mineralised acellular protrusions into articular cartilage and their possible role in osteoarthritis

Boyde, A., Davis, G. R., Mills, D., Zikmund, T., Cox, T. M., Adams, V. L., . . . Gallagher, J. A. (2014). On fragmenting, densely mineralised acellular protrusions into articular cartilage and their possible role in osteoarthritis. Journal of Anatomy, 225(4), 436-446. doi:10.1111/joa.12226

DOI
10.1111/joa.12226
Journal article

Purinergic signalling in cartilage (cancelled)

Gallagher, J. A., Dillon, J. P., Vindigni, G., Keenan, C. M., Piselli, D., & Wilson, P. J. (2014). Purinergic signalling in cartilage (cancelled). PURINERGIC SIGNALLING, 10(4), 704. Retrieved from https://www.webofscience.com/

Journal article

Reversible Keratopathy Due to Hypertyrosinaemia Following Intermittent Low-Dose Nitisinone in Alkaptonuria: A Case Report

Stewart, R. M. K., Briggs, M. C., Jarvis, J. C., Gallagher, J. A., & Ranganath, L. (2014). Reversible Keratopathy Due to Hypertyrosinaemia Following Intermittent Low-Dose Nitisinone in Alkaptonuria: A Case Report. JIMD REPORTS, VOL 17, 17, 1-6. doi:10.1007/8904_2014_307

DOI
10.1007/8904_2014_307
Journal article

THE CASE IS CRACKED: IDENTIFICATION OF A NEW SUSPECT IN THE INITIATION OF OSTEOARTHRITIS

Boyde, A., Davis, G. R., Jeffery, N., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2014). THE CASE IS CRACKED: IDENTIFICATION OF A NEW SUSPECT IN THE INITIATION OF OSTEOARTHRITIS. In RHEUMATOLOGY Vol. 53 (pp. 46). Retrieved from https://www.webofscience.com/

Conference Paper

Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry

Hughes, A. T., Milan, A. M., Christensen, P., Ross, G., Davison, A. S., Gallagher, J. A., . . . Ranganath, L. R. (2014). Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 963, 106-112. doi:10.1016/j.jchromb.2014.06.002

DOI
10.1016/j.jchromb.2014.06.002
Journal article

2013

Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia

Zamboulis, D. E., Senior, J. M., Clegg, P. D., Gallagher, J. A., Carter, S. D., & Milner, P. I. (2013). Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia. PURINERGIC SIGNALLING, 9(3), 383-393. doi:10.1007/s11302-013-9356-5

DOI
10.1007/s11302-013-9356-5
Journal article

2012

Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition

Taylor, A. M., Preston, A. J., Paulk, N. K., Sutherland, H., Keenan, C. M., Wilson, P. J. M., . . . Jarvis, J. C. (2012). Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition. Osteoarthritis and Cartilage, 20(8), 880-886. doi:10.1016/j.joca.2012.04.013

DOI
10.1016/j.joca.2012.04.013
Journal article

Primary human osteoblast cultures.

Dillon, J. P., Waring-Green, V. J., Taylor, A. M., Wilson, P. J. M., Birch, M., Gartland, A., & Gallagher, J. A. (2012). Primary human osteoblast cultures.. In Unknown Book (Vol. 816, pp. 3-18). doi:10.1007/978-1-61779-415-5_1

DOI
10.1007/978-1-61779-415-5_1
Chapter

Identification of trabecular excrescences, novel microanatomical structures, present in bone in osteoarthropathies

Taylor, A. M., Boyde, A., Davidson, J. S., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2012). Identification of trabecular excrescences, novel microanatomical structures, present in bone in osteoarthropathies. European Cells and Materials, 23, 300-309.

Journal article

Purinergic signalling in osteoblasts.

Gartland, A., Orriss, I. R., Rumney, R. M. H., Bond, A. P., Arnett, T., & Gallagher, J. A. (2012). Purinergic signalling in osteoblasts.. Frontiers in bioscience (Landmark edition), 17(1), 16-29. doi:10.2741/3912

DOI
10.2741/3912
Journal article

2011

The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria

Taylor, A. M., Boyde, A., Wilson, P. J. M., Jarvis, J. C., Davidson, J. S., Hunt, J. A., . . . Gallagher, J. A. (2011). The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria. ARTHRITIS AND RHEUMATISM, 63(12), 3887-3896. doi:10.1002/art.30606

DOI
10.1002/art.30606
Journal article

The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.

Taylor, A., Boyde, A., Wilson, P., Jarvis, J., Davidson, J., Hunt, J., . . . Gallagher, J. (2011). The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.. Arthritis and rheumatism, 63(12), 3887-3896.

Journal article

Development of an in vitro model to investigate joint ochronosis in alkaptonuria.

Tinti, L., Taylor, A. M., Santucci, A., Wlodarski, B., Wilson, P. J., Jarvis, J. C., . . . Gallagher, J. A. (2011). Development of an in vitro model to investigate joint ochronosis in alkaptonuria.. Rheumatology (Oxford, England), 50(2), 271-277. doi:10.1093/rheumatology/keq246

DOI
10.1093/rheumatology/keq246
Journal article

A National Survey of General Practitioners in the United Kingdom to establish a Registry for the Ultra-rare disease, Alkaptonuria: challenges, possible solutions and persistent barriers.

Ranganath, L., Taylor, A. M., Shenkin, A., Fraser, W. D., Jarvis, J., Gallagher, J. A., & Sireau, N. (2011). A National Survey of General Practitioners in the United Kingdom to establish a Registry for the Ultra-rare disease, Alkaptonuria: challenges, possible solutions and persistent barriers.. J Inherited Metabolic Disease, In Press.

Journal article

2010

Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes.

Braconi, D., Laschi, M., Taylor, A. M., Bernardini, G., Spreafico, A., Tinti, L., . . . Santucci, A. (2010). Proteomic and redox-proteomic evaluation of homogentisic acid and ascorbic acid effects on human articular chondrocytes.. Journal of cellular biochemistry, 111(4), 922-932. doi:10.1002/jcb.22780

DOI
10.1002/jcb.22780
Journal article

Evaluation of antioxidant drugs for the treatment of ochronotic alkaptonuria in an in vitro human cell model.

Tinti, L., Spreafico, A., Braconi, D., Millucci, L., Bernardini, G., Chellini, F., . . . Santucci, A. (2010). Evaluation of antioxidant drugs for the treatment of ochronotic alkaptonuria in an in vitro human cell model.. Journal of cellular physiology, 225(1), 84-91. doi:10.1002/jcp.22199

DOI
10.1002/jcp.22199
Journal article

The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro.

Agrawal, A., Buckley, K. A., Bowers, K., Furber, M., Gallagher, J. A., & Gartland, A. (2010). The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro.. Purinergic signalling, 6(3), 307-315. doi:10.1007/s11302-010-9181-z

DOI
10.1007/s11302-010-9181-z
Journal article

Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment

Taylor, A. M., Wlodarski, B., Prior, I. A., Wilson, P. J. M., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2010). Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment. RHEUMATOLOGY, 49(7), 1412-1414. doi:10.1093/rheumatology/keq027

DOI
10.1093/rheumatology/keq027
Journal article

2008

Alkaptonuria - a review of surgical and autopsy pathology

Helliwell, T. R., Gallagher, J. A., & Ranganath, L. (2008). Alkaptonuria - a review of surgical and autopsy pathology. HISTOPATHOLOGY, 53(5), 503-512. doi:10.1111/j.1365-2559.2008.03000.x

DOI
10.1111/j.1365-2559.2008.03000.x
Journal article

Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line.

Burrell, H. E., Simpson, A. W. M., Mehat, S., McCreavy, D. T., Durham, B., Fraser, W. D., . . . Gallagher, J. A. (2008). Potentiation of ATP- and bradykinin-induced [Ca2+]c responses by PTHrP peptides in the HaCaT cell line.. The Journal of investigative dermatology, 128(5), 1107-1115. doi:10.1038/sj.jid.5701159

DOI
10.1038/sj.jid.5701159
Journal article

2007

Caveolin-1 and caveolin-3 regulate Ca2+ homeostasis of single smooth muscle cells from rat cerebral resistance arteries.

Kamishima, T., Burdyga, T., Gallagher, J. A., & Quayle, J. M. (2007). Caveolin-1 and caveolin-3 regulate Ca2+ homeostasis of single smooth muscle cells from rat cerebral resistance arteries.. American journal of physiology. Heart and circulatory physiology, 293(1), H204-H214. doi:10.1152/ajpheart.00669.2006

DOI
10.1152/ajpheart.00669.2006
Journal article

Multicenter blinded analysis of RT-PCR detection methods for paramyxoviruses in relation to Paget's disease of bone.

Ralston, S. H., Afzal, M. A., Helfrich, M. H., Fraser, W. D., Gallagher, J. A., Mee, A., & Rima, B. (2007). Multicenter blinded analysis of RT-PCR detection methods for paramyxoviruses in relation to Paget's disease of bone.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 22(4), 569-577. doi:10.1359/jbmr.070103

DOI
10.1359/jbmr.070103
Journal article

PPAR agonists modulate human osteoclast formation and activity in vitro.

Chan, B. Y., Gartland, A., Wilson, P. J. M., Buckley, K. A., Dillon, J. P., Fraser, W. D., & Gallagher, J. A. (2007). PPAR agonists modulate human osteoclast formation and activity in vitro.. Bone, 40(1), 149-159. doi:10.1016/j.bone.2006.07.029

DOI
10.1016/j.bone.2006.07.029
Journal article

The Circadian Rhythm of Osteoprotegerin and its Association with Parathyroid Hormone Secretion

Joseph, F., Chan, B. Y., Durham, B. H., Ahmad, A. M., Vinjamuri, S., Gallagher, J. A., . . . Fraser, W. D. (2007). The Circadian Rhythm of Osteoprotegerin and its Association with Parathyroid Hormone Secretion. J Clin Endocrinol Metab, 92(8), 3230-3238. doi:10.1021/jc.2006-1832

DOI
10.1021/jc.2006-1832
Journal article

2005

Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface.

Burrell, H. E., Wlodarski, B., Foster, B. J., Buckley, K. A., Sharpe, G. R., Quayle, J. M., . . . Gallagher, J. A. (2005). Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface.. The Journal of biological chemistry, 280(33), 29667-29676. doi:10.1074/jbc.m505381200

DOI
10.1074/jbc.m505381200
Journal article

Differential effect of PPAR agonists on generation of Human osteoclasts in vitro

Chan, B. Y., Buckley, K. A., Gartland, A., Fraser, W. D., & Gallagher, J. A. (2005). Differential effect of PPAR agonists on generation of Human osteoclasts in vitro. Clinical Chemistry and Applied Molecular Biology, 355, S13-S14.

Journal article

Human Cell Culture Protocols: Isolation and Culture of Human Osteoblasts.

Gartland, A., Buckley, K. A., Dillon, J. B., Curran, J. M., Hunt, J. A., & Gallagher, J. A. (2005). Human Cell Culture Protocols: Isolation and Culture of Human Osteoblasts.. In J. Picotre (Ed.), Methods in Molecular Medicine. 2nd edition (Vol. 107, pp. 29-54). Totowa, New Jersey: Humana Press.

Chapter

Human osteoclast culture from peripheral blood monocytes: phenotypic characterization and quantitation of resorption

Buckley, K. A., Chan, B. Y., Fraser, W. D., & Gallagher, J. A. (2005). Human osteoclast culture from peripheral blood monocytes: phenotypic characterization and quantitation of resorption. Methods Mol Med, 107, 55-68. Retrieved from http://www.ncbi.nlm.nih.gov/

Journal article

Human osteoclast culture from peripheral blood monocytes: phenotypic characterization and quantitation of resorption.

Buckley, K. A., Chan, B. Y. Y., Fraser, W. D., & Gallagher, J. A. (2005). Human osteoclast culture from peripheral blood monocytes: phenotypic characterization and quantitation of resorption.. In Unknown Book (Vol. 107, pp. 55-68). doi:10.1385/1-59259-861-7:055

DOI
10.1385/1-59259-861-7:055
Chapter

Isolation and culture of human osteoblasts.

Gartland, A., Buckley, K. A., Dillon, J. P., Curran, J. M., Hunt, J. A., & Gallagher, J. A. (2005). Isolation and culture of human osteoblasts.. Methods in molecular medicine, 107, 29-54. doi:10.1385/1-59259-861-7:029

DOI
10.1385/1-59259-861-7:029
Journal article

The circadian rhythm of osteoprotegerin and its association with Parathyroid Hormone Secretion in Non-Osteoporotic Elderly postmenopausal women

Joseph, F., Chan, B. Y., White, H. D., Ahmad, A. M., Durham, B. H., Joshi, A., . . . Fraser, W. D. (2005). The circadian rhythm of osteoprotegerin and its association with Parathyroid Hormone Secretion in Non-Osteoporotic Elderly postmenopausal women. Bone, 36, S259.

Journal article

The effects of extracellular nucleotides on EGF-Induced C-FOS Gene Expression

Gartland, A., Fraser, W. D., & Gallagher, J. A. (2005). The effects of extracellular nucleotides on EGF-Induced C-FOS Gene Expression. Bone, 36(2), S257.

Journal article

The inflammatory potential of biphasic calcium phosphate granules in osteoblast/macrophage co-culture

Curran, J. M., Gallagher, J. A., & Hunt, J. A. (2005). The inflammatory potential of biphasic calcium phosphate granules in osteoblast/macrophage co-culture. BIOMATERIALS, 26(26), 5313-5320. doi:10.1016/j.biomaterials.2005.01.065

DOI
10.1016/j.biomaterials.2005.01.065
Journal article

2004

ATP P2 receptors and regulation of bone effector cells.

Gallagher, J. A. (2004). ATP P2 receptors and regulation of bone effector cells.. Journal of musculoskeletal & neuronal interactions, 4(2), 125-127.

Journal article

Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar.

Dacquin, R., Mee, P. J., Kawaguchi, J., Olmsted-Davis, E. A., Gallagher, J. A., Nichols, J., . . . Smith, A. (2004). Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar.. Developmental dynamics : an official publication of the American Association of Anatomists, 229(4), 826-834. doi:10.1002/dvdy.20003

DOI
10.1002/dvdy.20003
Journal article

2003

Effect of anticoagulants and storage temperature on the stability of receptor activator for nuclear factor-kappa B ligand and osteoprotegerin in plasma and serum.

Chan, B. Y. Y., Buckley, K. A., Durham, B. H., Gallagher, J. A., & Fraser, W. D. (2003). Effect of anticoagulants and storage temperature on the stability of receptor activator for nuclear factor-kappa B ligand and osteoprotegerin in plasma and serum.. Clinical chemistry, 49(12), 2083-2085. doi:10.1373/clinchem.2003.023747

DOI
10.1373/clinchem.2003.023747
Journal article

Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitro.

Gartland, A., Buckley, K. A., Bowler, W. B., & Gallagher, J. A. (2003). Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitro.. Calcified tissue international, 73(4), 361-369. doi:10.1007/s00223-002-2098-y

DOI
10.1007/s00223-002-2098-y
Journal article

DNA Vaccine

Gallagher, J. A., Mccreavy, D. T., & Fraser, W. D. (2003). DNA Vaccine.

Patent

Immuno Polymerase Chain Reaction Method

Fraser, W. D., Mccreavy, D. T., & Gallagher, J. A. (2003). Immuno Polymerase Chain Reaction Method.

Patent

Quantitative Evaluation of the Biocompatible and Osteogenic Properties of a Range of Biphasic Calcium Phosphate (BCP) Granules Using Primary Cultures of Human Osteoblasts and Monocytes

Rice, J. M., Hunt, J. A., & Gallagher, J. A. (2003). Quantitative Evaluation of the Biocompatible and Osteogenic Properties of a Range of Biphasic Calcium Phosphate (BCP) Granules Using Primary Cultures of Human Osteoblasts and Monocytes. Calcified Tissue International, 72(6), 726-736. doi:10.1007/s00223-002-2045-y

DOI
10.1007/s00223-002-2045-y
Journal article

Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.

Burrell, H. E., Bowler, W. B., Gallagher, J. A., & Sharpe, G. R. (2003). Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.. The Journal of investigative dermatology, 120(3), 440-447. doi:10.1046/j.1523-1747.2003.12050.x

DOI
10.1046/j.1523-1747.2003.12050.x
Journal article

'Human keratinocytes express multiple P2Y-receptors: Evidence for functional P2Y1, P2Y2, and P2Y4 receptors'

Burrell, H. E., Bowler, W. B., Gallagher, J. A., & Sharpe, G. R. (2003). 'Human keratinocytes express multiple P2Y-receptors: Evidence for functional P2Y1, P2Y2, and P2Y4 receptors'. Journal of Investigative Dermatology, 120(3), 440-447.

Journal article

'Multinucleated osteoclast formation in vivo and in vitro by P2X7 receptor-deficient mice

Gartland, A., Buckley, K. A., Hipskind, R. A., Perry, M. J., Tobias, J. H., Buell, G., . . . Gallagher, J. A. (2003). 'Multinucleated osteoclast formation in vivo and in vitro by P2X7 receptor-deficient mice. Critical Reviews in Eukaryotic Gene Expression, 13(2-4), 243-253.

Journal article

Human osteoblast culture.

Gallagher, J. A. (2003). Human osteoblast culture.. Methods in molecular medicine, 80, 3-18. doi:10.1385/1-59259-366-6:3

DOI
10.1385/1-59259-366-6:3
Journal article

P2 Receptors in Bone - Modulation of Osteoclast Formation and Activity via P2X7 Activation.

Gartland, A., Buckley, K. A., Hipskind, R. A., Bowler, W. B., & Gallagher, J. A. (2003). P2 Receptors in Bone - Modulation of Osteoclast Formation and Activity via P2X7 Activation.. Critical Reviews in Eukaryotic Gene Expression, 13(2-4), 237-242.

Journal article

P2 receptors in bone--modulation of osteoclast formation and activity via P2X7 activation.

Gartland, A., Buckley, K. A., Hipskind, R. A., Bowler, W. B., & Gallagher, J. A. (2003). P2 receptors in bone--modulation of osteoclast formation and activity via P2X7 activation.. Critical reviews in eukaryotic gene expression, 13(2-4), 237-242. doi:10.1615/critreveukaryotgeneexpr.v13.i24.140

DOI
10.1615/critreveukaryotgeneexpr.v13.i24.140
Journal article

P2X7 receptor-deficient mice maintain the ability to form multinucleated osteoclasts in vivo and in vitro.

Gartland, A., Buckley, K. A., Hipskind, R. A., Perry, M. J., Tobias, J. H., Buell, G., . . . Gallagher, J. A. (2003). P2X7 receptor-deficient mice maintain the ability to form multinucleated osteoclasts in vivo and in vitro.. Crit Reviews in Eukaryotic Gene Expression, 13(2-4), 243-253.

Journal article

Quantitative assessment of the response of primary derived human osteoblasts and macrophages to a range of nanotopography surfaces in a single culture model in vitro

Rice, J. M., Hunt, J. A., Gallagher, J. A., Hanarp, P., Sutherland, D. S., & Gold, J. (2003). Quantitative assessment of the response of primary derived human osteoblasts and macrophages to a range of nanotopography surfaces in a single culture model in vitro. BIOMATERIALS, 24(26), 4799-4818. doi:10.1016/S0142-9612(03)00381-8

DOI
10.1016/S0142-9612(03)00381-8
Journal article

Release and interconversion of P2 receptor agonists by human osteoblast-like cells.

Buckley, K. A., Golding, S. L., Rice, J. M., Dillon, J. P., & Gallagher, J. A. (2003). Release and interconversion of P2 receptor agonists by human osteoblast-like cells.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(11), 1401-1410. doi:10.1096/fj.02-0940com

DOI
10.1096/fj.02-0940com
Journal article

2002

Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand.

Buckley, K. A., Hipskind, R. A., Gartland, A., Bowler, W. B., & Gallagher, J. A. (2002). Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand.. Bone, 31(5), 582-590. doi:10.1016/s8756-3282(02)00877-3

DOI
10.1016/s8756-3282(02)00877-3
Journal article

Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand

Buckley, K. A., Hipskind, R. A., Gartland, A., Bowler, W. B., & Gallagher, J. A. (2002). Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-kappa B ligand. Bone, 31(5), 582-590. Retrieved from http://www.ncbi.nlm.nih.gov/

Journal article

Expression and function of P2 receptors in bone

Gallagher, J. A., & Buckley, K. A. (2002). Expression and function of P2 receptors in bone. J Musculoskelet Neuronal Interact, 2(5), 432-439. Retrieved from http://www.ncbi.nlm.nih.gov/

Journal article

2001

Expression of a P2X7 receptor by a subpopulation of human osteoblasts.

Gartland, A., Hipskind, R. A., Gallagher, J. A., & Bowler, W. B. (2001). Expression of a P2X7 receptor by a subpopulation of human osteoblasts.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 16(5), 846-856. doi:10.1359/jbmr.2001.16.5.846

DOI
10.1359/jbmr.2001.16.5.846
Journal article

Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling.

Bowler, W. B., Buckley, K. A., Gartland, A., Hipskind, R. A., Bilbe, G., & Gallagher, J. A. (2001). Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling.. Bone, 28(5), 507-512. doi:10.1016/s8756-3282(01)00430-6

DOI
10.1016/s8756-3282(01)00430-6
Journal article

Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.

Buckley, K. A., Wagstaff, S. C., McKay, G., Gaw, A., Hipskind, R. A., Bilbe, G., . . . Bowler, W. B. (2001). Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.. The Journal of biological chemistry, 276(12), 9565-9571. doi:10.1074/jbc.m005672200

DOI
10.1074/jbc.m005672200
Journal article

Expression of a P2X7 receptor by a subpopulation of human osteoblasts

Gartland, A., Hipskind, R. A., Gallagher, J. A., & Bowler, W. B. (2001). Expression of a P2X7 receptor by a subpopulation of human osteoblasts. J Bone Miner Res, 16(5), 846-856. Retrieved from http://www.ncbi.nlm.nih.gov/

Journal article

Extracellular Nucleotide Signalling: A Mechanism for Integrating Local and Systemic Responses in the Activation of Bone Remodelling

Bowler, W. B., Buckley, K. A., Gartland, A., Hipskind, R. A., Bilbe, G., & Gallagher, J. A. (2001). Extracellular Nucleotide Signalling: A Mechanism for Integrating Local and Systemic Responses in the Activation of Bone Remodelling. Bone, 28(5), 507-512.

Journal article

2000

Cultured human retinal pigment epithelial cells differentially express thrombospondin-1,-2,-3, and-4

Carron, J. A., Hiscott, P., Hagan, S., Sheridan, C. M., Magee, R., & Gallagher, J. A. (2000). Cultured human retinal pigment epithelial cells differentially express thrombospondin-1,-2,-3, and-4. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 32(11-12), 1137-1142. doi:10.1016/S1357-2725(00)00065-0

DOI
10.1016/S1357-2725(00)00065-0
Journal article

Extracellular ATP activates multiple signalling pathways and potentiates growth factor-induced c-fos gene expression in MCF-7 breast cancer cells.

Wagstaff, S. C., Bowler, W. B., Gallagher, J. A., & Hipskind, R. A. (2000). Extracellular ATP activates multiple signalling pathways and potentiates growth factor-induced c-fos gene expression in MCF-7 breast cancer cells.. Carcinogenesis, 21(12), 2175-2181. doi:10.1093/carcin/21.12.2175

DOI
10.1093/carcin/21.12.2175
Journal article

Parathyroid hormone-related protein in the aetiology of fibrous dysplasia of bone in the McCune Albright syndrome.

Fraser, W. D., Walsh, C. A., Birch, M. A., Durham, B., Dillon, J. P., McCreavy, D., & Gallagher, J. A. (2000). Parathyroid hormone-related protein in the aetiology of fibrous dysplasia of bone in the McCune Albright syndrome.. Clinical endocrinology, 53(5), 621-628. doi:10.1046/j.1365-2265.2000.01112.x

DOI
10.1046/j.1365-2265.2000.01112.x
Journal article

A compound for use in medicine

Gallagher, J. A. (2000). A compound for use in medicine.

Patent

Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone.

Ooi, C. G., Walsh, C. A., Gallagher, J. A., & Fraser, W. D. (2000). Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone.. Bone, 27(3), 417-421. doi:10.1016/s8756-3282(00)00343-4

DOI
10.1016/s8756-3282(00)00343-4
Journal article

A CD36-binding peptide from thrombospondin-1 can stimulate resorption by osteoclasts in vitro.

Carron, J. A., Wagstaff, S. C., Gallagher, J. A., & Bowler, W. B. (2000). A CD36-binding peptide from thrombospondin-1 can stimulate resorption by osteoclasts in vitro.. Biochemical and biophysical research communications, 270(3), 1124-1127. doi:10.1006/bbrc.2000.2574

DOI
10.1006/bbrc.2000.2574
Journal article

Cytokine expression by cultured osteoblasts from patients with osteoporotic fractures.

Walsh, C. A., Birch, M. A., Fraser, W. D., Ginty, A. F., & Gallagher, J. A. (2000). Cytokine expression by cultured osteoblasts from patients with osteoporotic fractures.. International journal of experimental pathology, 81(2), 159-163. doi:10.1046/j.1365-2613.2000.00147.x

DOI
10.1046/j.1365-2613.2000.00147.x
Journal article

1999

Expression of members of the thrombospondin family by human skeletal tissues and cultured cells.

Carron, J. A., Bowler, W. B., Wagstaff, S. C., & Gallagher, J. A. (1999). Expression of members of the thrombospondin family by human skeletal tissues and cultured cells.. Biochemical and biophysical research communications, 263(2), 389-391. doi:10.1006/bbrc.1999.1380

DOI
10.1006/bbrc.1999.1380
Journal article

Signaling in human osteoblasts by extracellular nucleotides. Their weak induction of the c-fos proto-oncogene via Ca2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase.

Bowler, W. B., Dixon, C. J., Halleux, C., Maier, R., Bilbe, G., Fraser, W. D., . . . Hipskind, R. A. (1999). Signaling in human osteoblasts by extracellular nucleotides. Their weak induction of the c-fos proto-oncogene via Ca2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase.. The Journal of biological chemistry, 274(20), 14315-14324. doi:10.1074/jbc.274.20.14315

DOI
10.1074/jbc.274.20.14315
Journal article

1998

Novel methods

Gallagher, J. A. (1998). Novel methods.

Patent

G-protein coupled receptors in bone.

Bowler, W. B., Gallagher, J. A., & Bilbe, G. (1998). G-protein coupled receptors in bone.. Frontiers in bioscience : a journal and virtual library, 3, d769-d780. doi:10.2741/a320

DOI
10.2741/a320
Journal article

P2 receptor agonists, antagonists and modulators of endogenous ATP release

Gallagher, J. A. (1998). P2 receptor agonists, antagonists and modulators of endogenous ATP release.

Patent

Human keratinocytes express transcripts for three isoforms of parathyroid hormone-related protein (PTHrP), but not for the parathyroid hormone/PTHrP receptor: effects of 1,25(OH)2 vitamin D3.

Sharpe, G. R., Dillon, J. P., Durham, B., Gallagher, J. A., & Fraser, W. D. (1998). Human keratinocytes express transcripts for three isoforms of parathyroid hormone-related protein (PTHrP), but not for the parathyroid hormone/PTHrP receptor: effects of 1,25(OH)2 vitamin D3.. The British journal of dermatology, 138(6), 944-951. doi:10.1046/j.1365-2133.1998.02259.x

DOI
10.1046/j.1365-2133.1998.02259.x
Journal article

P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption.

Bowler, W. B., Littlewood-Evans, A., Bilbe, G., Gallagher, J. A., & Dixon, C. J. (1998). P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption.. Bone, 22(3), 195-200. doi:10.1016/s8756-3282(97)00280-9

DOI
10.1016/s8756-3282(97)00280-9
Journal article

Steroid bisphosphonates

Gallagher, J. A. (1998). Steroid bisphosphonates.

Patent

1997

Effects of PTH on PTHrP gene expression in human osteoblasts: up-regulation with the kinetics of an immediate early gene.

Walsh, C. A., Bowler, W. B., Bilbe, G., Fraser, W. D., & Gallagher, J. A. (1997). Effects of PTH on PTHrP gene expression in human osteoblasts: up-regulation with the kinetics of an immediate early gene.. Biochemical and biophysical research communications, 239(1), 155-159. doi:10.1006/bbrc.1997.7351

DOI
10.1006/bbrc.1997.7351
Journal article

1996

RT-PCR detection of cytokine transcripts in a series of cultured human meningiomas.

Boyle-Walsh, E., Birch, M., Gallagher, J. A., Speirs, V., White, M. C., Shenkin, A., & Fraser, W. D. (1996). RT-PCR detection of cytokine transcripts in a series of cultured human meningiomas.. The Journal of pathology, 178(4), 442-446. doi:3.0.co;2-i">10.1002/(sici)1096-9896(199604)178:4<442::aid-path521>3.0.co;2-i

DOI
10.1002/(sici)1096-9896(199604)178:4<442::aid-path521>3.0.co;2-i
Journal article

1995

Thrombospondin promotes resorption by osteoclasts in vitro.

Carron, J. A., Walsh, C. A., Fraser, W. D., & Gallagher, J. A. (1995). Thrombospondin promotes resorption by osteoclasts in vitro.. Biochemical and biophysical research communications, 213(3), 1017-1025. doi:10.1006/bbrc.1995.2230

DOI
10.1006/bbrc.1995.2230
Journal article

Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts.

Bowler, W. B., Birch, M. A., Gallagher, J. A., & Bilbe, G. (1995). Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 10(7), 1137-1145. doi:10.1002/jbmr.5650100720

DOI
10.1002/jbmr.5650100720
Journal article

Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: effects of glucocorticoids.

Walsh, C. A., Birch, M. A., Fraser, W. D., Lawton, R., Dorgan, J., Walsh, S., . . . Gallagher, J. A. (1995). Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: effects of glucocorticoids.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 10(1), 17-25. doi:10.1002/jbmr.5650100106

DOI
10.1002/jbmr.5650100106
Journal article

1994

Primary cultures of human bone-derived cells produce parathyroid hormone-related protein: a study of 40 patients of varying age and pathology.

Walsh, C. A., Birch, M. A., Fraser, W. D., Robinson, J., Lawton, R., Dorgan, J., . . . Gallagher, J. A. (1994). Primary cultures of human bone-derived cells produce parathyroid hormone-related protein: a study of 40 patients of varying age and pathology.. Bone and mineral, 27(1), 43-50. doi:10.1016/s0169-6009(08)80185-7

DOI
10.1016/s0169-6009(08)80185-7
Journal article

Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone.

Birch, M. A., Taylor, W., Fraser, W. D., Ralston, S. H., Hart, C. A., & Gallagher, J. A. (1994). Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 9(1), 11-16. doi:10.1002/jbmr.5650090103

DOI
10.1002/jbmr.5650090103
Journal article

1993

Hypercalcaemia due to parathyroid hormone-related protein: long-term circulating levels may not reflect tumour activity.

Savage, M. W., Fraser, W. D., Bodmer, C. W., Ginty, A. F., Gallagher, J. A., Robinson, J., & Williams, G. (1993). Hypercalcaemia due to parathyroid hormone-related protein: long-term circulating levels may not reflect tumour activity.. Clinical endocrinology, 39(6), 695-699. doi:10.1111/j.1365-2265.1993.tb02429.x

DOI
10.1111/j.1365-2265.1993.tb02429.x
Journal article

PCR detection of cytokines in normal human and pagetic osteoblast-like cells.

Birch, M. A., Ginty, A. F., Walsh, C. A., Fraser, W. D., Gallagher, J. A., & Bilbe, G. (1993). PCR detection of cytokines in normal human and pagetic osteoblast-like cells.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 8(10), 1155-1162. doi:10.1002/jbmr.5650081002

DOI
10.1002/jbmr.5650081002
Journal article

1991

Application of reflected light microscopy to identify and quantitate resorption by isolated osteoclasts.

Walsh, C. A., Beresford, J. N., Birch, M. A., Boothroyd, B., & Gallagher, J. A. (1991). Application of reflected light microscopy to identify and quantitate resorption by isolated osteoclasts.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 6(7), 661-671. doi:10.1002/jbmr.5650060703

DOI
10.1002/jbmr.5650060703
Journal article

1990

The effects of extracellular pH on bone resorption by avian osteoclasts in vitro.

Walsh, C. A., Dawson, W. E., Birch, M. A., & Gallagher, J. A. (1990). The effects of extracellular pH on bone resorption by avian osteoclasts in vitro.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 5(12), 1243-1247. doi:10.1002/jbmr.5650051209

DOI
10.1002/jbmr.5650051209
Journal article

Maintenance of cell viability in stored bone

Treble, N. J., Dorgan, J. C., & Gallagher, J. A. (1990). Maintenance of cell viability in stored bone. Spine, 15(8), 830-832. Retrieved from http://www.ncbi.nlm.nih.gov/

Journal article

1985

Vitamin D metabolites regulate osteocalcin synthesis and proliferation of human bone cells in vitro.

Skjødt, H., Gallagher, J. A., Beresford, J. N., Couch, M., Poser, J. W., & Russell, R. G. (1985). Vitamin D metabolites regulate osteocalcin synthesis and proliferation of human bone cells in vitro.. The Journal of endocrinology, 105(3), 391-396. doi:10.1677/joe.0.1050391

DOI
10.1677/joe.0.1050391
Journal article

The Effects of Mononuclear Cell Factor(MCF) and Interleukin-1 (IL-1) on Synthesis of Matrix by Skeletal and Articular Cells In Vitro

Gallagher, J. A., Beresford, J. N., Dillon, J. P., Richardson, H. J., Wood, D. D., & Russell, R. G. G. (1985). The Effects of Mononuclear Cell Factor(MCF) and Interleukin-1 (IL-1) on Synthesis of Matrix by Skeletal and Articular Cells In Vitro. Rheumatology, XXIV(suppl 1), 158-161. doi:10.1093/rheumatology/xxiv.suppl_1.158

DOI
10.1093/rheumatology/xxiv.suppl_1.158
Journal article

The Effects of Mononuclear Cell Factor(MCF) and Interleukin-1 (IL-1) on Synthesis of Matrix by Skeletal and Articular Cells In Vitro

Gallagher, J. A., Beresford, J. N., Dillon, J. P., Richardson, H. J., Wood, D. D., & Russell, R. G. G. (1985). The Effects of Mononuclear Cell Factor(MCF) and Interleukin-1 (IL-1) on Synthesis of Matrix by Skeletal and Articular Cells In Vitro. Rheumatology (United Kingdom), 24, 158-161. doi:10.1093/rheumatology/XXIV.suppl_1.158

DOI
10.1093/rheumatology/XXIV.suppl_1.158
Journal article

1984

The effects of monocyte-conditioned medium and interleukin 1 on the synthesis of collagenous and non-collagenous proteins by mouse bone and human bone cells in vitro.

Beresford, J. N., Gallagher, J. A., Gowen, M., Couch, M., Poser, J., Wood, D. D., & Russell, R. G. (1984). The effects of monocyte-conditioned medium and interleukin 1 on the synthesis of collagenous and non-collagenous proteins by mouse bone and human bone cells in vitro.. Biochimica et biophysica acta, 801(1), 58-65. doi:10.1016/0304-4165(84)90212-5

DOI
10.1016/0304-4165(84)90212-5
Journal article

Differential response of bone cells isolated by sequential digestion to dichloromethylenebisphonate in culture.

Guenther, H. L., Gallagher, J. A., & Fleisch, H. (1984). Differential response of bone cells isolated by sequential digestion to dichloromethylenebisphonate in culture.. Calcified tissue international, 36(5), 568-575. doi:10.1007/bf02405368

DOI
10.1007/bf02405368
Journal article

Studies of the growth of human bone-derived cells in culture using aqueous two-phase partition.

Sharpe, P. T., MacDonald, B. R., Gallagher, J. A., Treffry, T. E., & Russell, R. G. (1984). Studies of the growth of human bone-derived cells in culture using aqueous two-phase partition.. Bioscience reports, 4(5), 415-419. doi:10.1007/bf01122506

DOI
10.1007/bf01122506
Journal article

Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids.

Beresford, J. N., Gallagher, J. A., Poser, J. W., & Russell, R. G. (1984). Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids.. Metabolic bone disease & related research, 5(5), 229-234. doi:10.1016/0221-8747(84)90064-x

DOI
10.1016/0221-8747(84)90064-x
Journal article

1983

Hormonal regulation of osteocalcin production by human bone cells in vitro

Gallagher, J. A., Beresford, J., Sharrard, M., Poser, J., & Russell, R. G. G. (1983). Hormonal regulation of osteocalcin production by human bone cells in vitro. Metabolic Bone Disease and Related Research, 5(1), 49. doi:10.1016/0221-8747(83)90059-0

DOI
10.1016/0221-8747(83)90059-0
Journal article

1982

Rapid intracellular degradation of newly synthesized collagen by bone cells. Effect of dichloromethylenebisphosphonate.

Gallagher, J. A., Guenther, H. L., & Fleisch, H. A. (1982). Rapid intracellular degradation of newly synthesized collagen by bone cells. Effect of dichloromethylenebisphosphonate.. Biochimica et biophysica acta, 719(2), 349-355. doi:10.1016/0304-4165(82)90109-x

DOI
10.1016/0304-4165(82)90109-x
Journal article

1980

Histological observations on the failure of rachitic rat bones to respond to 1,25/OH)2D3.

Gallagher, J. A., & Lawson, D. E. (1980). Histological observations on the failure of rachitic rat bones to respond to 1,25/OH)2D3.. Calcified tissue international, 31(3), 215-223. doi:10.1007/bf02407184

DOI
10.1007/bf02407184
Journal article