Publications
Selected publications
- Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. (Journal article - 2020)
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. (Journal article - 2020)
- Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study (Journal article - 2018)
- Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS) (Journal article - 2018)
- Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department (Journal article - 2017)
- Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department (Journal article - 2015)
- The cost of diagnostic uncertainty: a prospective economic analysis of febrile children attending an NHS emergency department (Journal article - 2019)
- Accuracy of a Modified qSOFA Score for Predicting Critical Care Admission in Febrile Children (Journal article - 2020)
- Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study (Journal article - 2021)
- Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children. (Journal article - 2021)
2024
A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19.
Sandoe, J. A. T., Grozeva, D., Albur, M., Bond, S. E., Brookes-Howell, L., Dark, P., . . . PEACH Study Group. (2024). A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19.. The Journal of antimicrobial chemotherapy, dkae246. doi:10.1093/jac/dkae246
Susceptibility to childhood sepsis, contemporary management, and future directions.
Carter, M. J., Carrol, E. D., Ranjit, S., Mozun, R., Kissoon, N., Watson, R. S., & Schlapbach, L. J. (2024). Susceptibility to childhood sepsis, contemporary management, and future directions.. The Lancet. Child & adolescent health, 8(9), 682-694. doi:10.1016/s2352-4642(24)00141-x
The burden and contemporary epidemiology of sepsis in children.
Watson, R. S., Carrol, E. D., Carter, M. J., Kissoon, N., Ranjit, S., & Schlapbach, L. J. (2024). The burden and contemporary epidemiology of sepsis in children.. The Lancet. Child & adolescent health, 8(9), 670-681. doi:10.1016/s2352-4642(24)00140-8
6040 Validating the national PEWS and LqSOFA in general practice: a retrospective cohort study
Clark, A., Cannings-John, R., Hughes, K., Carrol, E. D., Hay, A. D., Butler, C. C., . . . Sefton, G. (2024). 6040 Validating the national PEWS and LqSOFA in general practice: a retrospective cohort study. In British Association of General Paediatrics (pp. A98.2-A99). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2024-rcpch.139
6471 Performance of eight different severity scores to predict critical care admission in paediatric inpatients treated for sepsis: a retrospective cohort study
Deef, M., Bracken, A., Lane, S., Gittings, R., Curran, R., Foreman, R., . . . Carrol, E. D. (2024). 6471 Performance of eight different severity scores to predict critical care admission in paediatric inpatients treated for sepsis: a retrospective cohort study. In Paediatric Critical Care Society (pp. A314.1-A314). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2024-rcpch.491
The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study.
Webb, E. J. D., Howdon, D., Bestwick, R., King, N., Sandoe, J. A. T., Euden, J., . . . PEACH Study Group. (2024). The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study.. The Journal of antimicrobial chemotherapy, 79(8), 1831-1842. doi:10.1093/jac/dkae167
Enhancing sepsis biomarker development: key considerations from public and private perspectives.
Llitjos, J. -F., Carrol, E. D., Osuchowski, M. F., Bonneville, M., Scicluna, B. P., Payen, D., . . . Sepsis biomarker workshop group. (2024). Enhancing sepsis biomarker development: key considerations from public and private perspectives.. Critical care (London, England), 28(1), 238. doi:10.1186/s13054-024-05032-9
Rapid Classification and Differentiation of Sepsis-Related Pathogens Using FT-IR Spectroscopy.
Ahmed, S., Albahri, J., Shams, S., Sosa-Portugal, S., Lima, C., Xu, Y., . . . Goodacre, R. (2024). Rapid Classification and Differentiation of Sepsis-Related Pathogens Using FT-IR Spectroscopy.. Microorganisms, 12(7), 1415. doi:10.3390/microorganisms12071415
Assessing acutely ill children in general practice using the National PEWS and LqSOFA clinical scores: a retrospective cohort study.
Clark, A., Cannings-John, R., Carrol, E. D., Thomas-Jones, E., Sefton, G., Hay, A. D., . . . Hughes, K. (2024). Assessing acutely ill children in general practice using the National PEWS and LqSOFA clinical scores: a retrospective cohort study.. The British journal of general practice : the journal of the Royal College of General Practitioners, BJGP.2023.0638. doi:10.3399/bjgp.2023.0638
Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection
Naseem, R., Howe, N., Pretorius, S., Williams, C., Lendrem, C., Pallmann, P., & Carrol, E. D. (n.d.). Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection. NIHR Open Research, 4, 35. doi:10.3310/nihropenres.13568.1
Evidence of quality of life for hospitalised patients with COVID-19: a scoping review.
Webb, E. J., King, N., Howdon, D., Carrol, E. D., Euden, J., Howard, P., . . . Procalcitonin: Evaluation of Antibiotic use in COVID-19 Hospitalised Patients (PEACH) Study Team. (2024). Evidence of quality of life for hospitalised patients with COVID-19: a scoping review.. Health technology assessment (Winchester, England), 1-23. doi:10.3310/atpr4281
Equity in medical devices: trainers and educators play a vital role.
Whitehead, M., Carrol, E., Kee, F., Ali, R., & Holmes, C. (2024). Equity in medical devices: trainers and educators play a vital role.. BMJ (Clinical research ed.), 385, q1091. doi:10.1136/bmj.q1091
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.
Schlapbach, L. J., Ganesamoorthy, D., Wilson, C., Raman, S., George, S., Snelling, P. J., . . . RAPIDS Study Group. (2024). Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.. The Lancet. Child & adolescent health, 8(5), 325-338. doi:10.1016/s2352-4642(24)00017-8
Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases.
Yeoh, S., Estrada-Rivadeneyra, D., Jackson, H., Keren, I., Galassini, R., Cooray, S., . . . PERFORM, DIAMONDS and UK KD Genetic Consortia. (2024). Plasma Protein Biomarkers Distinguish Multisystem Inflammatory Syndrome in Children From Other Pediatric Infectious and Inflammatory Diseases.. The Pediatric infectious disease journal, 43(5), 444-453. doi:10.1097/inf.0000000000004267
System-wide approaches to antimicrobial therapy and antimicrobial resistance in the UK: the AMR-X framework.
AMR-X Collaborators. (2024). System-wide approaches to antimicrobial therapy and antimicrobial resistance in the UK: the AMR-X framework.. The Lancet. Microbe, 5(5), e500-e507. doi:10.1016/s2666-5247(24)00003-x
Bacterial discrimination by Fourier transform infrared spectroscopy, MALDI-mass spectrometry and whole-genome sequencing.
McGalliard, R., Muhamadali, H., AlMasoud, N., Haldenby, S., Romero-Soriano, V., Allman, E., . . . Goodacre, R. (2024). Bacterial discrimination by Fourier transform infrared spectroscopy, MALDI-mass spectrometry and whole-genome sequencing.. Future microbiology. doi:10.2217/fmb-2024-0043
Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.
Sanchez-Pinto, L. N., Bennett, T. D., DeWitt, P. E., Russell, S., Rebull, M. N., Martin, B., . . . Wynn, J. L. (2024). Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.. JAMA, 331(8), 675-686. doi:10.1001/jama.2024.0196
International Consensus Criteria for Pediatric Sepsis and Septic Shock.
Schlapbach, L. J., Watson, R. S., Sorce, L. R., Argent, A. C., Menon, K., Hall, M. W., . . . Society of Critical Care Medicine Pediatric Sepsis Definition Task Force. (2024). International Consensus Criteria for Pediatric Sepsis and Septic Shock.. JAMA, 331(8), 665-674. doi:10.1001/jama.2024.0179
Identifying critically ill children in Malawi: A modified qSOFA score for low-resource settings.
Kumwenda, M., Assies, R., Snik, I., Chatima, G., Langton, J., Chimalizeni, Y., . . . Calis, J. C. J. (2024). Identifying critically ill children in Malawi: A modified qSOFA score for low-resource settings.. PLOS global public health, 4(1), e0002388. doi:10.1371/journal.pgph.0002388
Which low urgent triaged febrile children are suitable for a fast track? An observational European study.
Tan, C. D., Vermont, C. L., Zachariasse, J. M., von Both, U., Carrol, E. D., Eleftheriou, I., . . . PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union). (2024). Which low urgent triaged febrile children are suitable for a fast track? An observational European study.. Emergency medicine journal : EMJ, emermed-2023-213375. doi:10.1136/emermed-2023-213375
Molecular antimicrobial susceptibility testing in sepsis.
Martin-Loeches, I., Pereira, J. G., Teoh, T. K., Barlow, G., Dortet, L., Carrol, E. D., . . . Textoris, J. (2024). Molecular antimicrobial susceptibility testing in sepsis.. Future microbiology. doi:10.2217/fmb-2023-0128
2023
Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study).
Henley, J., Brookes-Howell, L., Euden, J., Pallmann, P., Llewelyn, M., Howard, P., . . . PEACH consortium (Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients). (2023). Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study).. BMJ open, 13(12), e077117. doi:10.1136/bmjopen-2023-077117
The Aetiology and Global Impact of Paediatric Sepsis
Bracken, A., Lenihan, R., Khanijau, A., & Carrol, E. D. (n.d.). The Aetiology and Global Impact of Paediatric Sepsis. Current Pediatrics Reports, 11(4), 204-213. doi:10.1007/s40124-023-00305-3
A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study.
Jackson, H. R., Zandstra, J., Menikou, S., Hamilton, M. S., McArdle, A. J., Fischer, R., . . . PERFORM consortium. (2023). A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study.. The Lancet. Digital health, 5(11), e774-e785. doi:10.1016/s2589-7500(23)00149-8
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe.
Kolberg, L., Khanijau, A., van der Velden, F. J. S., Herberg, J., De, T., Galassini, R., . . . PERFORM Consortium. (2023). Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, ciad615. doi:10.1093/cid/ciad615
Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study
Tan, C. D., Vermont, C. L., Zachariasse, J. M., von Both, U., Eleftheriou, I., Emonts, M., . . . Geissler, J. (n.d.). Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study. European Journal of Pediatrics. doi:10.1007/s00431-023-05056-3
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study
Shah, P., Voice, M., Calvo-Bado, L., Rivero-Calle, I., Morris, S., Nijman, R., . . . Herberg, J. (2023). Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. LANCET REGIONAL HEALTH-EUROPE, 32. doi:10.1016/j.lanepe.2023.100707
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study
Shah, P., Voice, M., Calvo-Bado, L., Rivero-Calle, I., Morris, S., Nijman, R., . . . Geissler, J. (2023). Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. The Lancet Regional Health - Europe, 32, 100682. doi:10.1016/j.lanepe.2023.100682
The economic burden experienced by carers of children who had a critical deterioration at a tertiary children's hospital in the United Kingdom (the DETECT study): an online survey
Costa, E., Mateus, C., Carter, B., Siner, S., Jones, D., Evans, L., . . . Sefton, G. (2023). The economic burden experienced by carers of children who had a critical deterioration at a tertiary children's hospital in the United Kingdom (the DETECT study): an online survey. BMC PEDIATRICS, 23(1). doi:10.1186/s12887-023-04268-8
External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children.
Martin, A. J., van der Velden, F. J. S., von Both, U., Tsolia, M. N., Zenz, W., Sagmeister, M., . . . PERFORM consortium. (2023). External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children.. Archives of disease in childhood, archdischild-2023-325869. doi:10.1136/archdischild-2023-325869
Clinical predictors of encephalitis in UK adults-A multi-centre prospective observational cohort study.
Defres, S., Tharmaratnam, K., Michael, B. D., Ellul, M., Davies, N. W. S., Easton, A., . . . Solomon, T. (2023). Clinical predictors of encephalitis in UK adults-A multi-centre prospective observational cohort study.. PloS one, 18(8), e0282645. doi:10.1371/journal.pone.0282645
Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.
Habgood-Coote, D., Wilson, C., Shimizu, C., Barendregt, A. M., Philipsen, R., Galassini, R., . . . Kaforou, M. (2023). Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.. Med (New York, N.Y.), S2666-6340(23)00194-0. doi:10.1016/j.medj.2023.06.007
Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.
Willems, E., Gloerich, J., Suppers, A., van der Flier, M., van den Heuvel, L. P., van de Kar, N., . . . PERFORM consortium. (2023). Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.. iScience, 26(8), 107257. doi:10.1016/j.isci.2023.107257
Making the invisible visible: what can we do about biased AI in medical devices?
Whitehead, M., Carrol, E., Kee, F., & Holmes, C. (2023). Making the invisible visible: what can we do about biased AI in medical devices?. BMJ-BRITISH MEDICAL JOURNAL, 382. doi:10.1136/bmj.p1893
Biobanking and consenting to research: a qualitative thematic analysis of young people's perspectives in the North East of England.
van der Velden, F. J. S., Lim, E., Gills, L., Broadey, J., Hayes, L., Roberts, E., . . . DIAMONDS consortium. (2023). Biobanking and consenting to research: a qualitative thematic analysis of young people's perspectives in the North East of England.. BMC medical ethics, 24(1), 47. doi:10.1186/s12910-023-00925-w
Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom.
Costa, E., Mateus, C., Carter, B., Saron, H., Eyton-Chong, C. -K., Mehta, F., . . . Sefton, G. (2023). Using technology to reduce critical deterioration (the DETECT study): a cost analysis of care costs at a tertiary children's hospital in the United Kingdom.. BMC health services research, 23(1), 725. doi:10.1186/s12913-023-09739-3
720 Feasibility of a CQUIN framework for PEWS score and deterioration: post-hoc analysis of response times from a tertiary children’s hospital
Deef, M., Lewtas, J., Majid, S., Bracken, A., Team, D., Sefton, G., & Carrol, E. D. (2023). 720 Feasibility of a CQUIN framework for PEWS score and deterioration: post-hoc analysis of response times from a tertiary children’s hospital. In Paediatric Critical Care Society (pp. A338.2-A339). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2023-rcpch.534
Operationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce.
Carrol, E. D., Ranjit, S., Menon, K. D., Bennett, T. D., Sanchez-Pinto, L. N. J., Zimmerman, J. J. C., . . . Argent, A. C. (2023). Operationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce. PEDIATRIC CRITICAL CARE MEDICINE, 24(6), E263-E271. doi:10.1097/PCC.0000000000003263
Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature.
Jackson, H. R., Miglietta, L., Habgood-Coote, D., D'Souza, G., Shah, P., Nichols, S., . . . EUCLIDS, PERFORM and DIAMONDS Consortia. (2023). Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature.. Journal of the Pediatric Infectious Diseases Society, piad035. doi:10.1093/jpids/piad035
Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study
Schoenbuchner, S. M., Huang, C., Waldron, C. -A., Thomas-Jones, E., Hood, K., Carrol, E. D., & Pallmann, P. (2023). Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. TRIALS, 24(1). doi:10.1186/s13063-022-06956-9
Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis.
Patel, H., Sintou, A., Chowdhury, R. A., Rothery, S., Iacob, A. O., Prasad, S., . . . DIAMONDS consortium. (2023). Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis.. JAMA network open, 6(5), e2314291. doi:10.1001/jamanetworkopen.2023.14291
Are children with prolonged fever at a higher risk for serious illness? A prospective observational study
Nijman, R. G., Tan, C. D., Hagedoorn, N. N., Nieboer, D., Herberg, J. A., Balode, A., . . . Maconochie, I. K. (2023). Are children with prolonged fever at a higher risk for serious illness? A prospective observational study. ARCHIVES OF DISEASE IN CHILDHOOD. doi:10.1136/archdischild-2023-325343
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study.
Channon-Wells, S., Vito, O., McArdle, A. J., Seaby, E. G., Patel, H., Shah, P., . . . Best Available Treatment Study (BATS) consortium. (2023). Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study.. The Lancet. Rheumatology, 5(4), e184-e199. doi:10.1016/s2665-9913(23)00029-2
Reporting of Social Determinants of Health in Pediatric Sepsis Studies*
Menon, K. R., Sorce, L., Argent, A. D., Bennett, T. D., Carrol, E., Kissoon, N., . . . Ranjit, S. (2023). Reporting of Social Determinants of Health in Pediatric Sepsis Studies*. PEDIATRIC CRITICAL CARE MEDICINE, 24(4), 301-310. doi:10.1097/PCC.0000000000003184
Adeno-associated virus 2 infection in children with non-A-E hepatitis.
Ho, A., Orton, R., Tayler, R., Asamaphan, P., Herder, V., Davis, C., . . . Thomson, E. C. (2023). Adeno-associated virus 2 infection in children with non-A-E hepatitis.. Nature. doi:10.1038/s41586-023-05948-2
Genomic investigations of unexplained acute hepatitis in children.
Morfopoulou, S., Buddle, S., Montaguth, O. E. T., Atkinson, L., Guerra-Assunção, J. A., Marjaneh, M. M., . . . Breuer, J. (2023). Genomic investigations of unexplained acute hepatitis in children.. Nature. doi:10.1038/s41586-023-06003-w
'ZOOMing' in on Consulting with Children and Parents Remotely to Co-Create Health Information Resources.
Saron, H., Munro, J., Young, R., Carrol, E. D., Porter, D., Cantwell, R., . . . Carter, B. (2023). 'ZOOMing' in on Consulting with Children and Parents Remotely to Co-Create Health Information Resources.. Children (Basel, Switzerland), 10(3), 539. doi:10.3390/children10030539
European study confirms the combination of fever and petechial rash as an important warning sign for childhood sepsis and meningitis.
Kohlmaier, B., Leitner, M., Hagedoorn, N. N., Borensztajn, D. M., von Both, U., Carrol, E. D., . . . PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union). (2023). European study confirms the combination of fever and petechial rash as an important warning sign for childhood sepsis and meningitis.. Acta paediatrica (Oslo, Norway : 1992). doi:10.1111/apa.16740
Febrile illness in high-risk children: a prospective, international observational study
van der Velden, F. J. S., de Vries, G., Martin, A., Lim, E., von Both, U., Kolberg, L., . . . Emonts, M. (2022). Febrile illness in high-risk children: a prospective, international observational study. EUROPEAN JOURNAL OF PEDIATRICS. doi:10.1007/s00431-022-04642-1
Febrile illness in high-risk children: a prospective, international observational study (Vol 182, pg 543, 2023)
van der Velden, F. J. S., de Vries, G., Martin, A., Lim, E., von Both, U., Kolberg, L., . . . Emonts, M. (2023). Febrile illness in high-risk children: a prospective, international observational study (Vol 182, pg 543, 2023). EUROPEAN JOURNAL OF PEDIATRICS. doi:10.1007/s00431-022-04788-y
Group A streptococcal disease in paediatric inpatients: a European perspective (Vol 182, pg 697, 2023)
Boeddha, N. P., Atkins, L., de Groot, R., Driessen, G., Hazelzet, J., Zenz, W., . . . Emonts, M. (2023). Group A streptococcal disease in paediatric inpatients: a European perspective (Vol 182, pg 697, 2023). EUROPEAN JOURNAL OF PEDIATRICS. doi:10.1007/s00431-022-04787-z
2022
Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians.
Dewez, J. E., Pembrey, L., Nijman, R. G., Del Torso, S., Grossman, Z., Hadjipanayis, A., . . . Yeung, S. (2022). Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians.. PloS one, 17(12), e0275336. doi:10.1371/journal.pone.0275336
Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study
Tan, C. D., van der Walle, E. E. P. L., Vermont, C. L., von Both, U., Carrol, E. D., Eleftheriou, I., . . . Moll, H. A. (2022). Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study. EUROPEAN JOURNAL OF PEDIATRICS, 181(12), 4199-4209. doi:10.1007/s00431-022-04606-5
Hemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study
Hagedoorn, N. N., Boeddha, N. P., Kohlfuerst, D. S., Anderson, S., Carrol, E. D., Agapow, P., . . . Emonts, M. (2022). Hemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study. PEDIATRIC CRITICAL CARE MEDICINE, 23(12), E543-E554. doi:10.1097/PCC.0000000000003056
Mid-Regional Pro-Adrenomedullin in Combination With Pediatric Early Warning Scores for Risk Stratification of Febrile Children Presenting to the Emergency Department: Secondary Analysis of a Nonprespecified United Kingdom Cohort Study*
Lenihan, R. A. F., Ang, J., Pallmann, P., Romaine, S. T., Waldron, C. -A., Thomas-Jones, E., . . . Carrol, E. D. (2022). Mid-Regional Pro-Adrenomedullin in Combination With Pediatric Early Warning Scores for Risk Stratification of Febrile Children Presenting to the Emergency Department: Secondary Analysis of a Nonprespecified United Kingdom Cohort Study*. PEDIATRIC CRITICAL CARE MEDICINE, 23(12), 980-989. doi:10.1097/PCC.0000000000003075
Group A streptococcal disease in paediatric inpatients: a European perspective.
Boeddha, N. P., Atkins, L., de Groot, R., Driessen, G., Hazelzet, J., Zenz, W., . . . Emonts, M. (2022). Group A streptococcal disease in paediatric inpatients: a European perspective.. European journal of pediatrics. doi:10.1007/s00431-022-04718-y
Procalcitonin Evaluation of Antibiotic Use in COVID-19 Hospitalised Patients (PEACH): Protocol for a Retrospective Observational Study
Euden, J., Pallmann, P., Grozeva, D., Albur, M., Bond, S. E., Brookes-Howell, L., . . . PEACH, S. G. (2022). Procalcitonin Evaluation of Antibiotic Use in COVID-19 Hospitalised Patients (PEACH): Protocol for a Retrospective Observational Study. METHODS AND PROTOCOLS, 5(6). doi:10.3390/mps5060095
OP029 [Emerging Sciences / Technology » Innovations]: THE CLINICAL EFFECTIVENESS OF DYNAMIC ELECTRONIC TRACKING AND ESCALATION TO REDUCE CRITICAL CARE TRANSFERS (THE DETECT STUDY)
Sefton, G., Carter, B., Lane, S., Mehta, F., Eyton Chong, C., Siner, S., . . . Carrol, E. D. (2022). OP029 [Emerging Sciences / Technology » Innovations]: THE CLINICAL EFFECTIVENESS OF DYNAMIC ELECTRONIC TRACKING AND ESCALATION TO REDUCE CRITICAL CARE TRANSFERS (THE DETECT STUDY). Pediatric Critical Care Medicine, 23(Supplement 1 11S). doi:10.1097/01.pcc.0000899796.61711.08
OP044 [Global health » Resource limited settings]: IDENTIFYING CRITICALLY ILL CHILDREN AT RISK OF DYING DURING HOSPITAL ADMISSION IN MALAWI: PROGNOSTIC ACCURACY OF A MODIFIED QSOFA SCORE FOR LOW-RESOURCE SETTINGS
Kumwenda, M., Assies, R., Snik, I., Chathima, G., Langton, J., Chimalizeni, Y., . . . Calis, J. C. (2022). OP044 [Global health » Resource limited settings]: IDENTIFYING CRITICALLY ILL CHILDREN AT RISK OF DYING DURING HOSPITAL ADMISSION IN MALAWI: PROGNOSTIC ACCURACY OF A MODIFIED QSOFA SCORE FOR LOW-RESOURCE SETTINGS. Pediatric Critical Care Medicine, 23(Supplement 1 11S). doi:10.1097/01.pcc.0000899856.14238.94
Reducing Antibiotic Exposure at the Beginning of Life
Schlapbach, L. J., & Carrol, E. D. (2022). Reducing Antibiotic Exposure at the Beginning of Life. JAMA NETWORK OPEN, 5(11). doi:10.1001/jamanetworkopen.2022.43705
Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data-authors' response
Llewelyn, M. J., West, R. M., Carrol, E. D., Pallmann, P., & Sandoe, J. A. T. (2022). Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data-authors' response. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(11), 3211-3212. doi:10.1093/jac/dkac315
Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study (Sept, 10.1007/s00431-022-04606-5, 2022)
Tan, C. D., van der Walle, E. E. P. L., Vermont, C. L., von Both, U., Carrol, E. D., Eleftheriou, I., . . . consortium, P. E. R. F. O. R. M. (2022). Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study (Sept, 10.1007/s00431-022-04606-5, 2022). EUROPEAN JOURNAL OF PEDIATRICS. doi:10.1007/s00431-022-04664-9
Clinical utility and acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): A prospective e-survey of parents and health professionals.
Carter, B., Saron, H., Blake, L., Eyton-Chong, C. -K., Dee, S., Evans, L., . . . Carrol, E. D. (2022). Clinical utility and acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): A prospective e-survey of parents and health professionals.. PloS one, 17(9), e0273666. doi:10.1371/journal.pone.0273666
Febrile children with comorbidities at the emergency department - a multicentre observational study
Borensztajn, D. M., Hagedoorn, N. N., Carrol, E. D., von Both, U., Emonts, M., van der Flier, M., . . . Moll, H. A. (2022). Febrile children with comorbidities at the emergency department - a multicentre observational study. EUROPEAN JOURNAL OF PEDIATRICS, 181(9), 3491-3500. doi:10.1007/s00431-022-04552-2
Navigating uncertain illness trajectories for young children with serious infectious illness: a modified grounded theory study
Neill, S., Bray, L., Carter, B., Roland, D., Carrol, E. D., Bayes, N., . . . Palmer-Hill, S. (2022). Navigating uncertain illness trajectories for young children with serious infectious illness: a modified grounded theory study. BMC HEALTH SERVICES RESEARCH, 22(1). doi:10.1186/s12913-022-08420-5
Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): A qualitative interview study
Saron, H., Carter, B., Siner, S., Preston, J., Peak, M., Mehta, F., . . . Sefton, G. (2022). Parents' experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic pediatric early warning system (the DETECT study): A qualitative interview study. FRONTIERS IN PEDIATRICS, 10. doi:10.3389/fped.2022.954738
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations.
Kumar, V., Pouw, R. B., Autio, M. I., Sagmeister, M. G., Phua, Z. Y., Borghini, L., . . . Davila, S. (2022). Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations.. American journal of human genetics, S0002-9297(22)00318-4. doi:10.1016/j.ajhg.2022.08.001
Sex differences in febrile children with respiratory symptoms attending European emergency departments: An observational multicenter study.
Tan, C. D., El Ouasghiri, S., von Both, U., Carrol, E. D., Emonts, M., van der Flier, M., . . . PERFORM consortium (Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union). (2022). Sex differences in febrile children with respiratory symptoms attending European emergency departments: An observational multicenter study.. PloS one, 17(8), e0271934. doi:10.1371/journal.pone.0271934
512 Comparison of seven paediatric early warning scores, including the proposed National PEWS for England, to predict critical deterioration events in hospitalised children: a retrospective cohort study
Bracken, A., Sefton, G., Lane, S., Team, D. S., Haines, C., Clerihew, L., . . . Carrol, E. (2022). 512 Comparison of seven paediatric early warning scores, including the proposed National PEWS for England, to predict critical deterioration events in hospitalised children: a retrospective cohort study. In Paediatric Critical Care Society (pp. A364-A365). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.588
928 An exploration of health professionals’ experiences and perceptions of the clinical utility and acceptability of an electronic paediatric early warning system (the DETECT study)
Saron, H., Carter, B., Carrol, E., & Sefton, G. (2022). 928 An exploration of health professionals’ experiences and perceptions of the clinical utility and acceptability of an electronic paediatric early warning system (the DETECT study). In Quality Improvement and Patient Safety (pp. A461.1-A461). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.747
Simultaneous Raman and infrared spectroscopy: a novel combination for studying bacterial infections at the single cell level
Lima, C., Ahmed, S., Xu, Y., Muhamadali, H., Parry, C., McGalliard, R. J., . . . Goodacre, R. (2022). Simultaneous Raman and infrared spectroscopy: a novel combination for studying bacterial infections at the single cell level. CHEMICAL SCIENCE. doi:10.1039/d2sc02493d
Health professionals' initial experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): a qualitative interview study
Carter, B., Saron, H., Siner, S., Preston, J., Peak, M., Mehta, F., . . . Carrol, E. D. (2022). Health professionals' initial experiences and perceptions of the acceptability of a whole-hospital, pro-active electronic paediatric early warning system (the DETECT study): a qualitative interview study. BMC PEDIATRICS, 22(1). doi:10.1186/s12887-022-03411-1
PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO protocol for a multicentre, open-label, randomised controlled trial
Euden, J., Thomas-Jones, E., Aston, S., Brookes-Howell, L., Carman, J., Carrol, E., . . . French, N. (2022). PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO protocol for a multicentre, open-label, randomised controlled trial. BMJ OPEN, 12(6). doi:10.1136/bmjopen-2022-063424
Osteoarticular Infections in Pediatric Hospitals in Europe: A Prospective Cohort Study From the EUCLIDS Consortium
Trobisch, A., Schweintzger, N. A., Kohlfurst, D. S., Sagmeister, M. G., Sperl, M., Grisold, A. J., . . . Consortium, E. U. C. L. I. D. S. (2022). Osteoarticular Infections in Pediatric Hospitals in Europe: A Prospective Cohort Study From the EUCLIDS Consortium. FRONTIERS IN PEDIATRICS, 10. doi:10.3389/fped.2022.744182
Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data
Llewelyn, M. J., Grozeva, D., Howard, P., Euden, J., Gerver, S. M., Hope, R., . . . Sandoe, J. A. T. (2022). Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(4), 1189-1196. doi:10.1093/jac/dkac017
P14 Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study
Euden, J., Howard, P., Powell, N., Llewelyn, M. J., Szakmany, T., Albur, M., . . . Sandoe, J. A. T. (2022). P14 Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. In JAC-ANTIMICROBIAL RESISTANCE Vol. 4. doi:10.1093/jacamr/dlac004.013
Shock Index in the early assessment of febrile children at the emergency department: a prospective multicentre study
Hagedoorn, N. N., Zachariasse, J. M., Borensztajn, D., Adriaansens, E., von Both, U., Carrol, E. D., . . . Moll, H. A. (2022). Shock Index in the early assessment of febrile children at the emergency department: a prospective multicentre study. ARCHIVES OF DISEASE IN CHILDHOOD, 107(2), 116-122. doi:10.1136/archdischild-2020-320992
Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial.
Waldron, C. -A., Thomas-Jones, E., Bernatoniene, J., Brookes-Howell, L., Faust, S. N., Harris, D., . . . Carrol, E. D. (2022). Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial.. BMJ open, 12(1), e047490. doi:10.1136/bmjopen-2020-047490
Characteristics and management of adolescents attending the ED with fever: a prospective multicentre study.
Borensztajn, D., Hagedoorn, N. N., Carrol, E., von Both, U., Dewez, J. E., Emonts, M., . . . PERFORM Consortium: Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union. (2022). Characteristics and management of adolescents attending the ED with fever: a prospective multicentre study.. BMJ open, 12(1), e053451. doi:10.1136/bmjopen-2021-053451
Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce*
Menon, K., Schlapbach, L. J., Akech, S., Argent, A., Biban, P., Carrol, E. D., . . . Sorce, L. R. (2022). Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce*. CRITICAL CARE MEDICINE, 50(1), 21-36. doi:10.1097/CCM.0000000000005294
IDENTIFYING CRITICALLY ILL CHILDREN AT RISK OF DYING DURING HOSPITAL ADMISSION IN MALAWI: PROGNOSTIC ACCURACY OF A MODIFIED QSOFA SCORE FOR LOW-RESOURCE SETTINGS
Kumwenda, M., Assies, R., Snik, I., Chathima, G., Langton, J., Chimalizeni, Y., . . . Calis, J. C. (2022). IDENTIFYING CRITICALLY ILL CHILDREN AT RISK OF DYING DURING HOSPITAL ADMISSION IN MALAWI: PROGNOSTIC ACCURACY OF A MODIFIED QSOFA SCORE FOR LOW-RESOURCE SETTINGS. In PEDIATRIC CRITICAL CARE MEDICINE Vol. 23. Retrieved from https://www.webofscience.com/
Rapid Viral Testing and Antibiotic Prescription in Febrile Children With Respiratory Symptoms Visiting Emergency Departments in Europe
Tan, C. D., Hagedoorn, N. N., Dewez, J. E., Borensztajn, D. M., von Both, U., Carrol, E. D., . . . Consortium, P. E. R. F. O. R. M. (2022). Rapid Viral Testing and Antibiotic Prescription in Febrile Children With Respiratory Symptoms Visiting Emergency Departments in Europe. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 41(1), 39-44. doi:10.1097/INF.0000000000003326
THE CLINICAL EFFECTIVENESS OF DYNAMIC ELECTRONIC TRACKING AND ESCALATION TO REDUCE CRITICAL CARE TRANSFERS (THE DETECT STUDY)
Sefton, G., Carter, B., Lane, S., Mehta, F., Chong, C. E., Siner, S., . . . Carrol, E. D. (2022). THE CLINICAL EFFECTIVENESS OF DYNAMIC ELECTRONIC TRACKING AND ESCALATION TO REDUCE CRITICAL CARE TRANSFERS (THE DETECT STUDY). In PEDIATRIC CRITICAL CARE MEDICINE Vol. 23. Retrieved from https://www.webofscience.com/
2021
Antibiotics for neonatal sepsis in low-income and middle-income countries-where to go from here?
Schlapbach, L. J., van Rossum, A., & Carrol, E. D. (2021). Antibiotics for neonatal sepsis in low-income and middle-income countries-where to go from here?. The Lancet. Infectious diseases, 21(12), 1617-1618. doi:10.1016/s1473-3099(21)00199-7
Detectable A Disintegrin and Metalloproteinase With Thrombospondin Motifs-1 in Serum Is Associated With Adverse Outcome in Pediatric Sepsis.
Boeddha, N. P., Driessen, G. J., Hagedoorn, N. N., Kohlfuerst, D. S., Hoggart, C. J., van Rijswijk, A. L., . . . Dik, W. A. (2021). Detectable A Disintegrin and Metalloproteinase With Thrombospondin Motifs-1 in Serum Is Associated With Adverse Outcome in Pediatric Sepsis.. Critical care explorations, 3(11), e0569. doi:10.1097/cce.0000000000000569
Unequal impact of the COVID-19 crisis on minority ethnic groups: a framework for understanding and addressing inequalities
Katikireddi, S. V., Lal, S., Carrol, E. D., Niedzwiedz, C. L., Khunti, K., Dundas, R., . . . Barr, B. (2021). Unequal impact of the COVID-19 crisis on minority ethnic groups: a framework for understanding and addressing inequalities. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 75(10), 970-974. doi:10.1136/jech-2020-216061
A NICE combination for predicting hospitalisation at the Emergency Department: a European multicentre observational study of febrile children
Borensztajn, D. M., Hagedoorn, N. N., Carrol, E. D., von Both, U., Dewez, J. E., Emonts, M., . . . Moll, H. A. (2021). A NICE combination for predicting hospitalisation at the Emergency Department: a European multicentre observational study of febrile children. LANCET REGIONAL HEALTH-EUROPE, 8. doi:10.1016/j.lanepe.2021.100173
Investigation of SARS-CoV-2 faecal shedding in the community: a prospective household cohort study (COVID-LIV) in the UK
Vaselli, N. M., Setiabudi, W., Subramaniam, K., Adams, E. R., Turtle, L., Iturriza-Gomara, M., . . . Hungerford, D. (2021). Investigation of SARS-CoV-2 faecal shedding in the community: a prospective household cohort study (COVID-LIV) in the UK. BMC INFECTIOUS DISEASES, 21(1). doi:10.1186/s12879-021-06443-7
A Novel Framework for Phenotyping Children With Suspected or Confirmed Infection for Future Biomarker Studies
Nijman, R. G., Oostenbrink, R., Moll, H. A., Casals-Pascual, C., von Both, U., Cunnington, A., . . . Ri, P. E. R. F. O. R. M. C. P. (2021). A Novel Framework for Phenotyping Children With Suspected or Confirmed Infection for Future Biomarker Studies. FRONTIERS IN PEDIATRICS, 9. doi:10.3389/fped.2021.688272
Navigating uncertain illness trajectories for young children with serious infectious illness: a mixed-methods modified grounded theory study
Neill, S., Bray, L., Carter, B., Roland, D., Carrol, E., Bayes, N., . . . Palmer-Hill, S. (2021). Navigating uncertain illness trajectories for young children with serious infectious illness: a mixed-methods modified grounded theory study. doi:10.1101/2021.07.06.21259650
Development and validation of a prediction model for invasive bacterial infections in febrile children at European Emergency Departments: MOFICHE, a prospective observational study
Hagedoorn, N. N., Borensztajn, D., Nijman, R. G., Nieboer, D., Herberg, J. A., Balode, A., . . . Moll, H. A. (2021). Development and validation of a prediction model for invasive bacterial infections in febrile children at European Emergency Departments: MOFICHE, a prospective observational study. ARCHIVES OF DISEASE IN CHILDHOOD, 106(7), 641-647. doi:10.1136/archdischild-2020-319794
Treatment of Multisystem Inflammatory Syndrome in Children
McArdle, A. J., Vito, O., Patel, H., Seaby, E. G., Shah, P., Wilson, C., . . . Levin, M. (2021). Treatment of Multisystem Inflammatory Syndrome in Children. NEW ENGLAND JOURNAL OF MEDICINE, 385(1), 11-22. doi:10.1056/NEJMoa2102968
Impact of Digital Educational Interventions to Support Parents Caring for Acutely Ill Children at Home and Factors That Affect Their Use: Protocol for a Systematic Review.
Milne-Ives, M., Neill, S., Bayes, N., Blair, M., Blewitt, J., Bray, L., . . . ASK SNIFF Consortium. (2021). Impact of Digital Educational Interventions to Support Parents Caring for Acutely Ill Children at Home and Factors That Affect Their Use: Protocol for a Systematic Review.. JMIR research protocols, 10(6), e27504. doi:10.2196/27504
Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study
Romaine, S. T., Sefton, G., Lim, E., Nijman, R. G., Bernatoniene, J., Clark, S., . . . Carrol, E. D. (2021). Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open, 11(5). doi:10.1136/bmjopen-2020-044091
Use of Procalcitonin during the First Wave of COVID-19 in the Acute NHS Hospitals: A Retrospective Observational Study
Powell, N., Howard, P., Llewelyn, M. J., Szakmany, T., Albur, M., Bond, S. E., . . . Sandoe, J. A. T. (2021). Use of Procalcitonin during the First Wave of COVID-19 in the Acute NHS Hospitals: A Retrospective Observational Study. ANTIBIOTICS-BASEL, 10(5). doi:10.3390/antibiotics10050516
Paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT): An e-survey of the experiences of parents and clinicians.
Carter, B., Fisher-Smith, D., Porter, D., Lane, S., Peak, M., Taylor-Robinson, D., . . . Carrol, E. D. (2021). Paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT): An e-survey of the experiences of parents and clinicians.. PLoS One, 16(4), e0249514. doi:10.1371/journal.pone.0249514
Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol
Setiabudi, W., Hungerford, D., Subramaniam, K., Vaselli, N. M., Shaw, V. E., Wilton, M., . . . French, N. (2021). Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol. BMJ Open, 11(3), e048317. doi:10.1136/bmjopen-2020-048317
Impact of a clinical decision rule on antibiotic prescription for children with suspected lower respiratory tract infections presenting to European emergency departments: a simulation study based on routine data
Hagedoorn, N. N., Wagenaar, J. H. L., Nieboer, D., Bath, D., Von Both, U., Carrol, E. D., . . . Moll, H. A. (2021). Impact of a clinical decision rule on antibiotic prescription for children with suspected lower respiratory tract infections presenting to European emergency departments: a simulation study based on routine data. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76(5), 1349-1357. doi:10.1093/jac/dkab023
Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children.
Nielsen, M. J., Baines, P., Jennings, R., Siner, S., Kolamunnage-Dona, R., Newland, P., . . . Carrol, E. D. (2021). Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children.. PLoS One, 16(2), e0246027. doi:10.1371/journal.pone.0246027
Impact of Digital Educational Interventions to Support Parents Caring for Acutely Ill Children at Home and Factors That Affect Their Use: Protocol for a Systematic Review (Preprint)
Milne-Ives, M., Neill, S., Bayes, N., Blair, M., Blewitt, J., Bray, L., . . . Meinert, E. (2021). Impact of Digital Educational Interventions to Support Parents Caring for Acutely Ill Children at Home and Factors That Affect Their Use: Protocol for a Systematic Review (Preprint). doi:10.2196/preprints.27504
Critical deterioration in children admitted to hospital, requiring emergency transfer to the Paediatric Intensive Care Unit
Sefton, G. (2021). Critical deterioration in children admitted to hospital, requiring emergency transfer to the Paediatric Intensive Care Unit.
Management of non-urgent paediatric emergency department attendances by GPs: a retrospective observational study
Leigh, S., Mehta, B., Dummer, L., Aird, H., McSorley, S., Oseyenum, V., . . . Carrol, E. D. (2021). Management of non-urgent paediatric emergency department attendances by GPs: a retrospective observational study. BRITISH JOURNAL OF GENERAL PRACTICE, 71(702), E22-E30. doi:10.3399/bjgp20X713885
Variation in hospital admission in febrile children evaluated at the Emergency Department (ED) in Europe: PERFORM, a multicentre prospective observational study
Borensztajn, D. M., Hagedoorn, N. N., Rivero Calle, I., Maconochie, I. K., von Both, U., Carrol, E. D., . . . Moll, H. A. (2021). Variation in hospital admission in febrile children evaluated at the Emergency Department (ED) in Europe: PERFORM, a multicentre prospective observational study. PLOS ONE, 16(1). doi:10.1371/journal.pone.0244810
2020
CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis
Wall, E. C., Brownridge, P., Laing, G., Terra, V. S., Mlozowa, V., Denis, B., . . . Brown, J. S. (2020). CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 10. doi:10.3389/fcimb.2020.603623
Title NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection
Grauslys, A., Phelan, M. M., Broughton, C., Baines, P. B., Jennings, R., Siner, S., . . . Carrol, E. D. (2020). Title NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-77319-0
Accuracy of a Modified qSOFA Score for Predicting Critical Care Admission in Febrile Children
Romaine, S. T., Potter, J., Khanijau, A., McGalliard, R. J., Wright, J. L., Sefton, G., . . . Carrol, E. D. (2020). Accuracy of a Modified qSOFA Score for Predicting Critical Care Admission in Febrile Children. Pediatrics, 146(4). doi:10.1542/peds.2020-0782
Childhood Adversity and Health After Physical Abuse.
Campbell, K. A., Gamarra, E., Frost, C. J., Choi, B., & Keenan, H. T. (2020). Childhood Adversity and Health After Physical Abuse.. Pediatrics, 146(4), e20200638. doi:10.1542/peds.2020-0638
Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy
McGalliard, R. J., McWilliam, S. J., Maguire, S., Jones, C. A., Jennings, R. J., Siner, S., . . . Carrol, E. D. (2020). Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy. PLOS ONE, 15(10). doi:10.1371/journal.pone.0240360
Variation in antibiotic prescription rates in febrile children presenting to emergency departments across Europe (MOFICHE): A multicentre observational study.
Hagedoorn, N. N., Borensztajn, D. M., Nijman, R., Balode, A., von Both, U., Carrol, E. D., . . . PERFORM consortium. (2020). Variation in antibiotic prescription rates in febrile children presenting to emergency departments across Europe (MOFICHE): A multicentre observational study.. PLoS medicine, 17(8). doi:10.1371/journal.pmed.1003208
What matters when managing childhood fever in the emergency department? A discrete-choice experiment comparing the preferences of parents and healthcare professionals in the UK
Leigh, S., Robinson, J., Yeung, S., Coenen, F., Carrol, E. D., & Niessen, L. W. (2020). What matters when managing childhood fever in the emergency department? A discrete-choice experiment comparing the preferences of parents and healthcare professionals in the UK. ARCHIVES OF DISEASE IN CHILDHOOD, 105(8), 765-771. doi:10.1136/archdischild-2019-318209
Biomarkers for the Discrimination of Acute Kawasaki Disease From Infections in Childhood
Zandstra, J., van de Geer, A., Tanck, M. W. T., Dimitriades, D. V. S. -B., Aarts, C. E. M., Dietz, S. M., . . . Kuijpers, T. W. (2020). Biomarkers for the Discrimination of Acute Kawasaki Disease From Infections in Childhood. FRONTIERS IN PEDIATRICS, 8. doi:10.3389/fped.2020.00355
A systematic review of the organizational, environmental, professional and child and family factors influencing the timing of admission to hospital for children with serious infectious illness
Carter, B., Roland, D., Bray, L., Harris, J., Pandey, P., Fox, J., . . . Neill, S. (2020). A systematic review of the organizational, environmental, professional and child and family factors influencing the timing of admission to hospital for children with serious infectious illness. PLOS ONE, 15(7). doi:10.1371/journal.pone.0236013
Pediatric Sepsis Definition-A Systematic Review Protocol by the Pediatric Sepsis Definition Taskforce.
Menon, K., Schlapbach, L. J., Akech, S., Argent, A., Chiotos, K., Chisti, M. J., . . . Sorce, L. R. (2020). Pediatric Sepsis Definition-A Systematic Review Protocol by the Pediatric Sepsis Definition Taskforce.. Critical care explorations, 2(6), e0123. doi:10.1097/cce.0000000000000123
Neuropsychological and psychiatric outcomes in encephalitis: A multi-centre case-control study.
Harris, L., Griem, J., Gummery, A., Marsh, L., Defres, S., Bhojak, M., . . . ENCEPH UK study group. (2020). Neuropsychological and psychiatric outcomes in encephalitis: A multi-centre case-control study.. PloS one, 15(3), e0230436. doi:10.1371/journal.pone.0230436
Characterization of Circulating Clostridium difficile Strains, Host Response and Intestinal Microbiome in Hospitalized Children With Diarrhea
Lees, E. A., Carrol, E. D., Ellaby, N. A. F., Roberts, P., Corless, C. E., Lenzi, L., . . . Pirmohamed, M. (2020). Characterization of Circulating Clostridium difficile Strains, Host Response and Intestinal Microbiome in Hospitalized Children With Diarrhea. The Pediatric infectious disease journal, 39(3), 221-228. doi:10.1097/inf.0000000000002559
Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children
Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., . . . Tissieres, P. (2020). Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. INTENSIVE CARE MEDICINE, 46(SUPPL 1), 1-9. doi:10.1007/s00134-019-05877-7
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., . . . Tissieres, P. (2020). Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. PEDIATRIC CRITICAL CARE MEDICINE, 21(2), E52-E106. doi:10.1097/PCC.0000000000002198
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children
Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., . . . Tissieres, P. (2020). Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. INTENSIVE CARE MEDICINE, 46(SUPPL 1), 10-67. doi:10.1007/s00134-019-05878-6
58. Acute Bacterial Meningitis
Griffiths, M. J., Carrol, E., & Ghadasan, R. (2020). 58. Acute Bacterial Meningitis. In Hunter's Tropical Medicine and Emerging Infectious Disease. Elsevier.
Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.
Weiss, S. L., Peters, M. J., Alhazzani, W., Agus, M. S. D., Flori, H. R., Inwald, D. P., . . . Tissieres, P. (2020). Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. PEDIATRIC CRITICAL CARE MEDICINE, 21(2), 186-195. doi:10.1097/PCC.0000000000002197
Personalising sepsis therapy through improved mechanistic understanding of phagocytic killing
Thompson, L. (2020). Personalising sepsis therapy through improved mechanistic understanding of phagocytic killing.
2019
Plasma lipid profiles discriminate bacterial from viral infection in febrile children
Wang, X., Nijman, R., Camuzeaux, S., Sands, C., Jackson, H., Kaforou, M., . . . Zukovskaja, V. (2019). Plasma lipid profiles discriminate bacterial from viral infection in febrile children. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-53721-1
BACTERIAL MENINGITIS IN MALAWIAN CHILDREN, 2000-2018
Nielsen, M., Ray, S. T. J., Kawaza, K., Denis, B., Gordon, S. B., Griffiths, M. J., . . . Tam, P. -Y. I. (2019). BACTERIAL MENINGITIS IN MALAWIAN CHILDREN, 2000-2018. In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Vol. 101 (pp. 146). Retrieved from https://www.webofscience.com/
Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers (DETECT): the protocol for a stepped wedge mixed method study to explore the clinical effectiveness, clinical utility and cost-effectiveness of an electronic physiological surveillance system for use in children
Sefton, G., Carter, B., Lane, S., Peak, M., Mateus, C., Preston, J., . . . Carrol, E. D. (2019). Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers (DETECT): the protocol for a stepped wedge mixed method study to explore the clinical effectiveness, clinical utility and cost-effectiveness of an electronic physiological surveillance system for use in children. BMC PEDIATRICS, 19(1). doi:10.1186/s12887-019-1745-7
Bacteremia in Childhood Life-Threatening Infections in Urban Gambia: EUCLIDS in West Africa
Secka, F., Herberg, J. A., Sarr, I., Darboe, S., Sey, G., Saidykhan, M., . . . Anderson, S. T. (2019). Bacteremia in Childhood Life-Threatening Infections in Urban Gambia: EUCLIDS in West Africa. Open Forum Infectious Diseases, 6(9). doi:10.1093/ofid/ofz332
Being ‘at-home’ on outpatient parenteral antimicrobial therapy (OPAT): a qualitative study of parents’ experiences of paediatric OPAT
Carter, B., Fisher-Smith, D., Porter, D., Lane, S., Peak, M., Taylor-Robinson, D. C., . . . Carrol, E. (2019). Being ‘at-home’ on outpatient parenteral antimicrobial therapy (OPAT): a qualitative study of parents’ experiences of paediatric OPAT. Archives of Disease in Childhood. Education and Practice Edition. doi:10.1136/archdischild-2019-317629
Diversity in the emergency care for febrile children in Europe: a questionnaire study.
Borensztajn, D., Yeung, S., Hagedoorn, N. N., Balode, A., von Both, U., Carrol, E. D., . . . Moll, H. A. (n.d.). Diversity in the emergency care for febrile children in Europe: a questionnaire study.. BMJ paediatrics open, 3(1), e000456. doi:10.1136/bmjpo-2019-000456
Viral and bacterial infection elicit distinct changes in plasma lipids in febrile children
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
Borghini, L., Png, E., Binder, A., Wright, V. J., Pinnock, E., de Groot, R., . . . Consortium, E. U. C. L. I. D. S. (2019). Identification of regulatory variants associated with genetic susceptibility to meningococcal disease. Scientific Reports, 9(1). doi:10.1038/s41598-019-43292-6
PO 8194 OPTIMISED INFORMED CONSENT FOR PARTICIPANTS IN A RANDOMISED CONTROLLED TRIAL IN RURAL UGANDA: A COMPARATIVE PROSPECTIVE COHORT STUDY
Ditai, J., Kanyago, J., Nambozo, R., Kanyago, N., Abeso, J., Olupot, P., . . . Storr, J. (2019). PO 8194 OPTIMISED INFORMED CONSENT FOR PARTICIPANTS IN A RANDOMISED CONTROLLED TRIAL IN RURAL UGANDA: A COMPARATIVE PROSPECTIVE COHORT STUDY. BMJ Global Health, 4(Suppl 3), A22.1-A22. doi:10.1136/bmjgh-2019-edc.55
BabyGel Pilot: a pilot cluster randomised trial of the provision of alcohol handgel to postpartum mothers to prevent neonatal and young infant Infection-related morbidity in the community
Ditai, J. (2019). BabyGel Pilot: a pilot cluster randomised trial of the provision of alcohol handgel to postpartum mothers to prevent neonatal and young infant Infection-related morbidity in the community. Pilot and Feasibility Studies, 5. doi:10.1186/s40814-019-0432-7
The cost of diagnostic uncertainty: a prospective economic analysis of febrile children attending an NHS emergency department
Leigh, S., Grant, A., Murray, N., Faragher, B., Desai, H., Dolan, S., . . . Carrol, E. D. (2019). The cost of diagnostic uncertainty: a prospective economic analysis of febrile children attending an NHS emergency department. BMC Medicine, 17. doi:10.1186/s12916-019-1275-z
Procalcitonin and Other Common Biomarkers Do Not Reliably Identify Patients at Risk for Bacterial Infection After Congenital Heart Surgery
D'Souza, S., Guhadasan, R., Jennings, R., Siner, S., Paulus, S., Thorburn, K., . . . Carrol, E. (2019). Procalcitonin and Other Common Biomarkers Do Not Reliably Identify Patients at Risk for Bacterial Infection After Congenital Heart Surgery. PEDIATRIC CRITICAL CARE MEDICINE, 20(3), 243-251. doi:10.1097/PCC.0000000000001826
In search of a primary outcome for community-based newborn infection trials in Eastern Uganda: a nested cohort study within the BabyGel pilot trial
Mobbs, N. A., Ditai, J., Abeso, J., Faragher, E. B., Carrol, E. D., Gladstone, M., . . . Weeks, A. D. (2019). In search of a primary outcome for community-based newborn infection trials in Eastern Uganda: a nested cohort study within the BabyGel pilot trial. PILOT AND FEASIBILITY STUDIES, 5(1). doi:10.1186/s40814-019-0428-3
"We have to clean ourselves to ensure that our children are healthy and beautiful": findings from a qualitative assessment of a hand hygiene poster in rural Uganda
Harrison, B. L., Ogara, C., Gladstone, M., Carrol, E. D., Dusabe-Richards, J., Medina-Lara, A., . . . Weeks, A. D. (2019). "We have to clean ourselves to ensure that our children are healthy and beautiful": findings from a qualitative assessment of a hand hygiene poster in rural Uganda. BMC PUBLIC HEALTH, 19. doi:10.1186/s12889-018-6343-3
2018
Optimising informed consent for participants in a randomised controlled trial in rural Uganda: a comparative prospective cohort mixed-methods study
Ditai, J., Kanyago, J., Nambozo, M. R., Odeke, N. M., Abeso, J., Dusabe-Richards, J., . . . Weeks, A. (2018). Optimising informed consent for participants in a randomised controlled trial in rural Uganda: a comparative prospective cohort mixed-methods study. Trials, 11 pages. doi:10.1186/s13063-018-3030-8
Preventing neonatal sepsis in rural Uganda: a cross-over study comparing the tolerance and acceptability of three alcohol-based hand rub formulations
Ditai, J., Mudoola, M., Gladstone, M., Abeso, J., Dusabe-Richards, J., Adengo, M., . . . Weeks, A. D. (2018). Preventing neonatal sepsis in rural Uganda: a cross-over study comparing the tolerance and acceptability of three alcohol-based hand rub formulations. BMC PUBLIC HEALTH, 18. doi:10.1186/s12889-018-6201-3
Delivery, setting and outcomes of paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT): a scoping review
Carter, B., Carrol, E. D., Porter, D., Peak, M., Taylor-Robinson, D., Fisher-Smith, D., & Blake, L. (2018). Delivery, setting and outcomes of paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT): a scoping review. BMJ OPEN, 8(11). doi:10.1136/bmjopen-2018-021603
To GP or not to GP: a natural experiment in children triaged to see a GP in a tertiary paediatric emergency department (ED)
Smith, L., Narang, Y., Pavon, A. B. I., Edwardson, K., Bowers, S., Jones, K., . . . Carrol, E. (2018). To GP or not to GP: a natural experiment in children triaged to see a GP in a tertiary paediatric emergency department (ED). BMJ Quality and Safety, 27(07), 521-528. doi:10.1136/bmjqs-2017-006605
Abstract P-034: CRITICAL DETERIORATION LEADING TO UNPLANNED ICU ADMISSION AND COMPLIANCE WITH THE CHAIN OF PREVENTION; A SYSTEMATIC REVIEW
Sefton, G., Carter, B., Lane, S., & Carrol, E. (2018). Abstract P-034: CRITICAL DETERIORATION LEADING TO UNPLANNED ICU ADMISSION AND COMPLIANCE WITH THE CHAIN OF PREVENTION; A SYSTEMATIC REVIEW. Pediatric Critical Care Medicine, 19(6S), 58-59. doi:10.1097/01.pcc.0000537491.08766.82
Abstract P-035: PRE-EXISTING RISK FACTORS FOR CRITICAL DETERIORATION LEADING TO UNPLANNED ADMISSION TO ICU IN PAEDIATRIC IN-PATIENTS; A SYSTEMATIC REVIEW
Sefton, G., Carter, B., Lane, S., & Carrol, E. (2018). Abstract P-035: PRE-EXISTING RISK FACTORS FOR CRITICAL DETERIORATION LEADING TO UNPLANNED ADMISSION TO ICU IN PAEDIATRIC IN-PATIENTS; A SYSTEMATIC REVIEW. Pediatric Critical Care Medicine, 19(6S), 59. doi:10.1097/01.pcc.0000537492.85894.97
Early diagnosis of severe infection
McGalliard, R. J., & Carrol, E. D. (2018). Early diagnosis of severe infection. Paediatrics and Child Health, 28(6), 249-253. doi:10.1016/j.paed.2018.04.001
Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study
Martinón-Torres, F., Salas, A., Rivero-Calle, I., Cebey-López, M., Pardo-Seco, J., Herberg, J. A., . . . Morillo Gutiérrez, B. (2018). Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet Child and Adolescent Health, 2(06), 404-414. doi:10.1016/S2352-4642(18)30113-5
Use of co-primary outcomes for trials of antimicrobial stewardship interventions
Gillespie, D., Francis, N. A., Carrol, E. D., Thomas-Jones, E., Butler, C. C., & Hood, K. (2018). Use of co-primary outcomes for trials of antimicrobial stewardship interventions. LANCET INFECTIOUS DISEASES, 18(6), 595-597. doi:10.1016/S1473-3099(18)30289-5
Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)
Boeddha, N. P., Schlapbach, L. J., Driessen, G. J., Herberg, J. A., Rivero-Calle, I., Cebey-Lopez, M., . . . Consortium, E. U. C. L. I. D. S. (2018). Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS). CRITICAL CARE, 22. doi:10.1186/s13054-018-2052-7
2017
Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study
Kulohoma, B. W., Marriage, F., Vasieva, O., Mankhambo, L., Nguyen, K., Molyneux, M. E., . . . Carrol, E. D. (2017). Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study. BMJ PAEDIATRICS OPEN, 1(1). doi:10.1136/bmjpo-2017-000092
Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department
Irwin, A. D., Grant, A., Williams, R., Kolamunnage-Dona, R., Drew, R. J., Paulus, S., . . . Carrol, E. D. (2017). Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department. Pediatrics, 140(2), 0. doi:10.1542/peds.2016-2853
Quantitative Proteomics of Cerebrospinal Fluid in Paediatric Pneumococcal Meningitis
Gomez-Baena, G., Bennett, R. J., Martinez-Rodriguez, C., Wnek, M., Laing, G., Hickey, G., . . . Carrol, E. D. (2017). Quantitative Proteomics of Cerebrospinal Fluid in Paediatric Pneumococcal Meningitis. Scientific Reports, 7. doi:10.1038/s41598-017-07127-6
A new horizon for sepsis: Personalised medicine: Hype or hope?
McGalliard, R. J., & Carrol, E. D. (2017). A new horizon for sepsis: Personalised medicine: Hype or hope?. New Horizons in Translational Medicine, 3(6), 289-293. doi:10.1016/j.nhtm.2017.06.002
G466(P) Performance characteristics of biomarkers of bacterial infection in children in the paediatric intensive care unit following cardiothoracic surgery
Guhadasan, R., D’Souza, S., Jennings, R., Paulus, S., Chesters, C., Downey, C., . . . Carrol, E. D. (2017). G466(P) Performance characteristics of biomarkers of bacterial infection in children in the paediatric intensive care unit following cardiothoracic surgery. In Paediatric Intensive Care Society and British Association for Paediatric Nephrology (pp. A183.3-A184). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2017-313087.458
A Feasibility Study of Quantifying Longitudinal Brain Changes in Herpes Simplex Virus (HSV) Encephalitis Using Magnetic Resonance Imaging (MRI) and Stereology
Defres, S., Keller, S. S., Das, K., Vidyasagar, R., Parkes, L. M., Burnside, G., . . . Solomon, T. (2017). A Feasibility Study of Quantifying Longitudinal Brain Changes in Herpes Simplex Virus (HSV) Encephalitis Using Magnetic Resonance Imaging (MRI) and Stereology. PLOS ONE, 12(01), 15 pages. doi:10.1371/journal.pone.0170215
Accuracy and Efficiency of Recording Pediatric Early Warning Scores Using an Electronic Physiological Surveillance System Compared With Traditional Paper-Based Documentation.
Sefton, G., Lane, S., Killen, R., Black, S., Lyon, M., Ampah, P., . . . Carrol, E. D. (2017). Accuracy and Efficiency of Recording Pediatric Early Warning Scores Using an Electronic Physiological Surveillance System Compared With Traditional Paper-Based Documentation. CIN-COMPUTERS INFORMATICS NURSING, 35(5), 228-236. doi:10.1097/CIN.0000000000000305
2016
Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies.
Martinon-Torres, F., Png, E., Khor, C. C., Davila, S., Wright, V. J., Sim, K. S., . . . Salas, A. (2016). Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies. SCIENTIFIC REPORTS, 6. doi:10.1038/srep35842
The role of <i>Clostridium difficile</i> in the paediatric and neonatal gut - a narrative review
Lees, E. A., Miyajima, F., Pirmohamed, M., & Carrol, E. D. (2016). The role of <i>Clostridium difficile</i> in the paediatric and neonatal gut - a narrative review. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 35(7), 1047-1057. doi:10.1007/s10096-016-2639-3
A pilot cluster randomised trial of alcohol-based hand rub to prevent community neonatal sepsis in rural Uganda
Ditai, J., Abeso, J., Mudoola, M., Faragher, B., Adengo, M., Richards, J. D., . . . Medina-Lara, A. (2016). A pilot cluster randomised trial of alcohol-based hand rub to prevent community neonatal sepsis in rural Uganda. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 123, 127. Retrieved from https://www.webofscience.com/
Optimising informed consent for participants in randomised controlled trials: A comparison of three different methods
Ditai, J., Abeso, J., Mudoola, M., Faragher, B., Adengo, M., Richards, J. D., . . . Weeks, A. (2016). Optimising informed consent for participants in randomised controlled trials: A comparison of three different methods. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 123, 127. Retrieved from https://www.webofscience.com/
G211 To GP or not to GP: evaluation of children triaged to see a GP in a tertiary Paediatric Emergency Department
Smith, L., Narang, Y., Edwardson, K., Cumbers, A., Bowers, S., Jones, K., . . . Ryan, M. (2016). G211 To GP or not to GP: evaluation of children triaged to see a GP in a tertiary Paediatric Emergency Department. Archives of Disease in Childhood, 101(Suppl 1), A115.3-A116. doi:10.1136/archdischild-2016-310863.202
G614 Accuracy and efficiency of recording paediatric early warning scores (PEWS) using electronic hand-held devices compared with traditional paper-based documentation
Sefton, G., Lane, S., Killen, R., Black, S., Lyon, M., Sproule, C., . . . Carrol, E. D. (2016). G614 Accuracy and efficiency of recording paediatric early warning scores (PEWS) using electronic hand-held devices compared with traditional paper-based documentation. Archives of Disease in Childhood, 101(Suppl 1), A365.1-A365. doi:10.1136/archdischild-2016-310863.599
Viridans Group Streptococcal Infections in Children After Chemotherapy or Stem Cell Transplantation <i>A 10-year Review From a Tertiary Pediatric Hospital</i>
Nielsen, M. J., Claxton, S., Pizer, B., Lane, S., Cooke, R. P. D., Paulus, S., & Carrol, E. D. (2016). Viridans Group Streptococcal Infections in Children After Chemotherapy or Stem Cell Transplantation <i>A 10-year Review From a Tertiary Pediatric Hospital</i>. MEDICINE, 95(9). doi:10.1097/MD.0000000000002952
Evaluation of mRNA Biomarkers to Identify Risk of Hospital Acquired Infections in Children Admitted to Paediatric Intensive Care Unit
Peronnet, E., Nguyen, K., Cerrato, E., Guhadasan, R., Venet, F., Textoris, J., . . . Carrol, E. D. (2016). Evaluation of mRNA Biomarkers to Identify Risk of Hospital Acquired Infections in Children Admitted to Paediatric Intensive Care Unit. PLOS ONE, 11(3). doi:10.1371/journal.pone.0152388
2015
Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children.
Lees, E. A., Ho, D. K. K., Guiver, M., Mankhambo, L. A., French, N., & Carrol, E. D. (2015). Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children.. New microbes and new infections, 8, 4-6. doi:10.1016/j.nmni.2015.08.001
Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children
Carrol, E. D., Lees, E. A., Ho, D. K., Guiver, M., Mankhambo, L. A., & French, N. (2015). Comparison of Binax NOW urine antigen test and pneumococcal DNA assay using qPCR before and after nasopharyngeal swabbing in healthy Malawian children. New Microbes New. doi:10.1016/j.nmni.2015.08.001
Osteomyelitis and septic arthritis in children: first data from the EUCLIDS network
Zenz, W., Trobisch, A., Klobassa, D., Binder, A., Sperl, M., Martinon-Torres, F., . . . -on, B. O. E. U. C. L. I. D. S. C. (n.d.). Osteomyelitis and septic arthritis in children: first data from the EUCLIDS network. Bone Abstracts. doi:10.1530/boneabs.4.p95
Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department
Irwin, A., Drew, R. J., Marshall, P., Nguyen, K., Hoyle, E., Macfarlane, K. A., . . . Carrol, E. (2015). Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department. Pediatrics, 135(4), 635-642. doi:10.1542/peds.2014-2061
What impact did a Paediatric Early Warning system have on emergency admissions to the paediatric intensive care unit? An observational cohort study
Sefton, G., McGrath, C., Tume, L., Lane, S., Lisboa, P. J. G., & Carrol, E. D. (2015). What impact did a Paediatric Early Warning system have on emergency admissions to the paediatric intensive care unit? An observational cohort study. INTENSIVE AND CRITICAL CARE NURSING, 31(2), 91-99. doi:10.1016/j.iccn.2014.01.001
Proteomic profiling to identify markers of bacterial meningitis
D. Carrol, E., Gómez-Baena, L., Laing, G., & Beynon, R. (n.d.). Proteomic profiling to identify markers of bacterial meningitis. European Journal of Molecular & Clinical Medicine, 2(2), 66. doi:10.1016/j.nhtm.2014.11.039
Affimers, new affinity reagents for life science research
Puard, V., Tan, K. -Y., Baldwin, K., Carrol, E., Patisson, R., Beynon, R., . . . Ferrigno, P. K. (2015). Affimers, new affinity reagents for life science research. In PROTEIN SCIENCE Vol. 24 (pp. 242). Retrieved from https://www.webofscience.com/
VIRIDANS GROUP STREPTOCOCCAL INFECTIONS IN CHILDREN FOLLOWING CHEMOTHERAPY OR STEM CELL TRANSPLANTATION-A TEN YEAR RETROSPECTIVE REVIEW FROM A TERTIARY PAEDIATRIC HOSPITAL
Nielsen, M. J., Claxton, S., Pizer, B., Cooke, R. P. D., Paulus, S., & Carrol, E. (2015). VIRIDANS GROUP STREPTOCOCCAL INFECTIONS IN CHILDREN FOLLOWING CHEMOTHERAPY OR STEM CELL TRANSPLANTATION-A TEN YEAR RETROSPECTIVE REVIEW FROM A TERTIARY PAEDIATRIC HOSPITAL. In PEDIATRIC BLOOD & CANCER Vol. 62 (pp. S387-S388). Retrieved from https://www.webofscience.com/
2014
Prognostic markers of meningococcal disease in children: recent advances and future challenges
Montero-Martin, M., Inwald, D. P., Carrol, E. D., & Martinon-Torres, F. (2014). Prognostic markers of meningococcal disease in children: recent advances and future challenges. EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 12(11), 1357-1369. doi:10.1586/14787210.2014.966079
Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens
Lees, E., Carrol, E., Gerrard, C., Hardiman, F., Howel, G., Timmis, A., . . . McNamara, P. (2014). Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens. BMC Infectious Diseases, 14. doi:10.1186/1471-2334-14-343
Bacterial Meningitis in Malawian Adults, Adolescents, and Children During the Era of Antiretroviral Scale-up and <i>Haemophilus</i> <i>influenzae</i> Type b Vaccination, 2000-2012
Wall, E. C., Everett, D. B., Mukaka, M., Bar-Zeev, N., Feasey, N., Jahn, A., . . . Heyderman, R. S. (2014). Bacterial Meningitis in Malawian Adults, Adolescents, and Children During the Era of Antiretroviral Scale-up and <i>Haemophilus</i> <i>influenzae</i> Type b Vaccination, 2000-2012. CLINICAL INFECTIOUS DISEASES, 58(10), E137-E145. doi:10.1093/cid/ciu057
ABSTRACT 106
Sefton, G., Lane, S., & Carrol, E. D. (2014). ABSTRACT 106. Pediatric Critical Care Medicine, 15, 29-30. doi:10.1097/01.pcc.0000448835.89804.43
Neurological Manifestations of Influenza Infection in Children and Adults: Results of a National British Surveillance Study
Goenka, A., Michael, B. D., Ledger, E., Hart, I. J., Absoud, M., Chow, G., . . . Kneen, R. (2014). Neurological Manifestations of Influenza Infection in Children and Adults: Results of a National British Surveillance Study. CLINICAL INFECTIOUS DISEASES, 58(6), 775-784. doi:10.1093/cid/cit922
Treating invasive Group A Streptococcal infections
Lees, E. A., & Carrol, E. D. (2014). Treating invasive Group A Streptococcal infections. Paediatrics and Child Health, 24(6), 242-247. doi:10.1016/j.paed.2014.01.001
2013
NEUROLOGICAL MANIFESTATIONS OF INFLUENZA INFECTION IN ADULTS AND CHILDREN: RESULTS OF A NATIONAL BRITISH SURVEILLANCE STUDY
Goenka, A., Michael, B., Ledger, E., Hart, I., Absoud, M., Chow, G., . . . Kneen, R. (2013). NEUROLOGICAL MANIFESTATIONS OF INFLUENZA INFECTION IN ADULTS AND CHILDREN: RESULTS OF A NATIONAL BRITISH SURVEILLANCE STUDY. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 84. doi:10.1136/jnnp-2013-306573.64
Commentaries on 'procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections' with a response from the review authors.
Sabhaney, V., Enarson, P., Irwin, A. D., & Carrol, E. D. (2013). Commentaries on 'procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections' with a response from the review authors.. Evidence-based child health : a Cochrane review journal, 8(4), 1372-1374. doi:10.1002/ebch.1928
A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis
Couto-Alves, A., Wright, V. J., Perumal, K., Binder, A., Carrol, E. D., Emonts, M., . . . Inwald, D. P. (2013). A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis. CRITICAL CARE, 17(2). doi:10.1186/cc12609
Risk Factors for Death and Severe Sequelae in Malawian Children With Bacterial Meningitis, 1997-2010
McCormick, D. W., Wilson, M. L., Mankhambo, L., Phiri, A., Chimalizeni, Y., Kawaza, K., . . . Molyneux, E. M. (2013). Risk Factors for Death and Severe Sequelae in Malawian Children With Bacterial Meningitis, 1997-2010. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 32(2), E54-E61. doi:10.1097/INF.0b013e31826faf5a
54 Acute Bacterial Meningitis
Guhadasan, R., & Carrol, E. D. (2013). 54 Acute Bacterial Meningitis. In Hunter's Tropical Medicine and Emerging Infectious Disease (pp. 501-507). Elsevier. doi:10.1016/b978-1-4160-4390-4.00054-0
2012
Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children
Irwin, A. D., Marriage, F., Mankhambo, L. A., Group, I. P. D. S., Jeffers, G., Kolamunnage-Dona, R., . . . Carrol, E. D. (2012). Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children. BMC Medical Genomics, 5(1). doi:10.1186/1755-8794-5-13
Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach
Everett, D. B., Cornick, J., Denis, B., Chewapreecha, C., Croucher, N., Harris, S., . . . Bentley, S. D. (2012). Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach. PLOS ONE, 7(9). doi:10.1371/journal.pone.0044250
Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children
Irwin, A. D., Marriage, F., Mankhambo, L. A., Jeffers, G., Kolamunnage-Dona, R., Guiver, M., . . . Carrol, E. D. (2012). Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children. BMC MEDICAL GENOMICS, 5. doi:10.1186/1755-8794-5-13
Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit
Paize, F., Sarginson, R., Makwana, N., Baines, P. B., Thomson, A. P. J., Sinha, I., . . . Parry, C. M. (2012). Changes in the sublingual microcirculation and endothelial adhesion molecules during the course of severe meningococcal disease treated in the paediatric intensive care unit. INTENSIVE CARE MEDICINE, 38(5), 863-871. doi:10.1007/s00134-012-2476-5
Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines
Kneen, R., Michael, B. D., Menson, E., Mehta, B., Easton, A., Hemingway, C., . . . Solomon, T. (2012). Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines. JOURNAL OF INFECTION, 64(5), 449-477. doi:10.1016/j.jinf.2011.11.013
Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines
Kneen, R., Michael, B. D., Menson, E., Mehta, B., Easton, A., Hemingway, C., . . . Solomon, T. (2012). Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines. Journal of Infection, 64(5), 449-477. doi:10.1016/j.jinf.2011.11.013
Acute Bacterial Meningitis
Guhadasan, R., & Carrol, E. D. (2013). Acute Bacterial Meningitis. In Hunter's Tropical Medicine and Emerging Infectious Disease (pp. 501-507). Elsevier. doi:10.1016/b978-1-4160-4390-4.00054-0
Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach.
Everett, D. B., Cornick, J., Denis, B., Chewapreecha, C., Croucher, N., Harris, S., . . . Bentley, S. D. (2012). Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach.. PLoS ONE, 7(9), e44250.
National guideline for the management of suspected viral encephalitis in children.
Kneen, R., Michael, B. D., Menson, E., Mehta, B., Easton, A., Hemingway, C., & Klapper, P. E. (2012). National guideline for the management of suspected viral encephalitis in children.. J Infect.
Risk Factors for Death and Severe Sequelae in Malawian Children with Bacterial
McCormick, D. W., Wilson, M. L., Mankhambo, L., Phiri, A., Chimalizeni, Y., Kawaza, K., & Denis, B. (2012). Risk Factors for Death and Severe Sequelae in Malawian Children with Bacterial. Pediatr Infect Dis J..
2011
Procalcitonin
Irwin, A. D., & Carrol, E. D. (2011). Procalcitonin. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 96(6), 228-233. doi:10.1136/archdischild-2011-300178
Meningococcal Disease in Children in Merseyside, England: A 31 Year Descriptive Study
Stanton, M. C., Taylor-Robinson, D., Harris, D., Paize, F., Makwana, N., Hackett, S. J., . . . Carrol, E. D. (2011). Meningococcal Disease in Children in Merseyside, England: A 31 Year Descriptive Study. PLOS ONE, 6(10). doi:10.1371/journal.pone.0025957
Angiopoietins as prognostic biomarkers and effector molecules in severe sepsis
Carrol, E. D. (2011). Angiopoietins as prognostic biomarkers and effector molecules in severe sepsis. CRITICAL CARE MEDICINE, 39(9), 2203-2204. doi:10.1097/CCM.0b013e31821f02bf
PCR Improves Diagnostic Yield from Lung Aspiration in Malawian Children with Radiologically Confirmed Pneumonia
Carrol, E. D., Mankhambo, L. A., Guiver, M., Banda, D. L., Denis, B., Dove, W., . . . Graham, S. M. (2011). PCR Improves Diagnostic Yield from Lung Aspiration in Malawian Children with Radiologically Confirmed Pneumonia. PLOS ONE, 6(6). doi:10.1371/journal.pone.0021042
Invasive <i>Streptococcus pneumoniae</i> in Children, Malawi, 2004-2006
Cornick, J. E., Everett, D. B., Broughton, C., Denis, B. B., Banda, D. L., Carrol, E. D., & Parry, C. M. (2011). Invasive <i>Streptococcus pneumoniae</i> in Children, Malawi, 2004-2006. EMERGING INFECTIOUS DISEASES, 17(6), 1107-1109. doi:10.3201/eid1706.101404
Ten Years of Surveillance for Invasive <i>Streptococcus pneumoniae</i> during the Era of Antiretroviral Scale-Up and Cotrimoxazole Prophylaxis in Malawi
Everett, D. B., Mukaka, M., Denis, B., Gordon, S. B., Carrol, E. D., van Oosterhout, J. J., . . . Heyderman, R. S. (2011). Ten Years of Surveillance for Invasive <i>Streptococcus pneumoniae</i> during the Era of Antiretroviral Scale-Up and Cotrimoxazole Prophylaxis in Malawi. PLOS ONE, 6(3). doi:10.1371/journal.pone.0017765
The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1
Carrol, E. D., Payton, A., Payne, D., Miyajima, F., Chaponda, M., Mankhambo, L. A., . . . Ollier, W. E. (2011). The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1. JOURNAL OF IMMUNOLOGY, 186(4), 2329-2335. doi:10.4049/jimmunol.1002402
Bacterial Meningitis
Guhadasan, R., & Carrol, E. D. (2011). Bacterial Meningitis. In A. Magill, D. R. Hill, G. T. Strickland, E. T. Ryan, & T. Solomon. (Eds.), HUNTER'S TROPICAL MEDICINE AND EMERGING INFECTIOUS DISEASES, Ninth Edition (pp. xxx-xxy). Chennai: Elsevier.
Diagnostic efficacy of activated partial thromboplastin time waveform and procalcitonin analysis in pediatric meningococcal sepsis
Paize, F., Carrol, E., Downey, C., Parry, C. M., Green, G., Diggle, P., . . . Toh, C. -H. (2011). Diagnostic efficacy of activated partial thromboplastin time waveform and procalcitonin analysis in pediatric meningococcal sepsis. PEDIATRIC CRITICAL CARE MEDICINE, 12(6), E322-E329. doi:10.1097/PCC.0b013e3182231034
Diagnostic efficacy of activated partial thromboplastin time waveform and procalcitonin analysis in pediatric meningococcal sepsis.
Paize, F., Carrol, E., Downey, C., Parry, C. M., Green, G., Diggle, P., . . . Toh, C. H. (2011). Diagnostic efficacy of activated partial thromboplastin time waveform and procalcitonin analysis in pediatric meningococcal sepsis.. Pediatr Crit Care Med, 12(6), e322-e329.
Impact of Human Immunodeficiency Virus Infection on the Etiology and Outcome of Severe Pneumonia in Malawian Children
Graham, S. M., Mankhambo, L., Phiri, A., Kaunda, S., Chikaonda, T., Mukaka, M., . . . Molyneux, M. E. (2011). Impact of Human Immunodeficiency Virus Infection on the Etiology and Outcome of Severe Pneumonia in Malawian Children. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 30(1), 33-38. doi:10.1097/INF.0b013e3181fcabe4
Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi.
Everett, D. B., Mukaka, M., Denis, B., Gordon, S. B., Carrol, E. D., vanOosterhout, J. J., . . . Heyderman, R. S. (2011). Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi.. PLoS One., 6(3), e17765..
2010
Susceptibility to Invasive Bacterial Infections in Children With Sickle Cell Disease
Battersby, A. J., Knox-Macaulay, H. H. M., & Carrol, E. D. (2010). Susceptibility to Invasive Bacterial Infections in Children With Sickle Cell Disease. PEDIATRIC BLOOD & CANCER, 55(3), 401-406. doi:10.1002/pbc.22461
Referrals for MMR immunisation in hospital
Ainsworth, E., Debenham, P., Carrol, E. D., & Riordan, F. A. I. (2010). Referrals for MMR immunisation in hospital. ARCHIVES OF DISEASE IN CHILDHOOD, 95(8), 639-641. doi:10.1136/adc.2009.162487
Comment on "IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis" and Comment on "IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis"
Carrol, E. D. (2010). Comment on "IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis" and Comment on "IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis". JOURNAL OF IMMUNOLOGY, 185(2), 789. doi:10.4049/jimmunol.1090052
The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children
Mankhambo, L. A., Banda, D. L., Jeffers, G., White, S. A., Balmer, P., Nkhoma, S., . . . Carrol, E. D. (2010). The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children. CRITICAL CARE, 14(3). doi:10.1186/cc9025
Meeting report: A celebration of the work of Professor Tony Hart, Liverpool, United Kingdom, 7 March 2009.
Cunliffe, N. A., Carrol, E. D., & Parry, C. M. (2010). Meeting report: A celebration of the work of Professor Tony Hart, Liverpool, United Kingdom, 7 March 2009.. The Journal of antimicrobial chemotherapy, 65(5), 822-826. doi:10.1093/jac/dkq055
Invasive group A streptococcal infections in children presenting to a paediatric intensive care unit in the North West of England
Timmis, A., Parkins, K., Kustos, I., Riordan, F. A. I., Efstratiou, A., & Carrol, E. D. (2010). Invasive group A streptococcal infections in children presenting to a paediatric intensive care unit in the North West of England. JOURNAL OF INFECTION, 60(2), 183-186. doi:10.1016/j.jinf.2009.12.001
<i>Streptococcus pneumoniae</i> infection in children is associated with degradation of surfactant protein D
Mackay, R. -M., Carrol, E., & Clark, H. (2010). <i>Streptococcus pneumoniae</i> infection in children is associated with degradation of surfactant protein D. In IMMUNOLOGY Vol. 131 (pp. 181). Retrieved from https://www.webofscience.com/
Genome-wide association study identifies variants in the <i>CFH</i> region associated with host susceptibility to meningococcal disease
Davila, S., Wright, V. J., Khor, C. C., Sim, K. S., Binder, A., Breunis, W. B., . . . Hibberd, M. L. (2010). Genome-wide association study identifies variants in the <i>CFH</i> region associated with host susceptibility to meningococcal disease. NATURE GENETICS, 42(9), 772-U63. doi:10.1038/ng.640
2009
Fatal histiocytic proliferative disorders in paediatric HIV infection with cytomegalovirus end-organ disease
Nastouli, E., Carrol, E., Malone, M., Riordan, A., & Lyall, H. (2009). Fatal histiocytic proliferative disorders in paediatric HIV infection with cytomegalovirus end-organ disease. BRITISH JOURNAL OF HAEMATOLOGY, 146(5), 580-582. doi:10.1111/j.1365-2141.2009.07813.x
The Diagnostic and Prognostic Accuracy of Five Markers of Serious Bacterial Infection in Malawian Children with Signs of Severe Infection
Carrol, E. D., Mankhambo, L. A., Jeffers, G., Parker, D., Guiver, M., Newland, P., . . . Hart, C. A. (2009). The Diagnostic and Prognostic Accuracy of Five Markers of Serious Bacterial Infection in Malawian Children with Signs of Severe Infection. PLOS ONE, 4(8). doi:10.1371/journal.pone.0006621
Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease
Payton, A., Payne, D., Mankhambo, L. A., Banda, D. L., Hart, C. A., Ollier, W. E. R., & Carrol, E. D. (2009). Nitric oxide synthase 2A (NOS2A) polymorphisms are not associated with invasive pneumococcal disease. BMC MEDICAL GENETICS, 10. doi:10.1186/1471-2350-10-28
Competitive Inhibition Flow Analysis Assay for the Non-Culture-Based Detection and Serotyping of Pneumococcal Capsular Polysaccharide
Findlow, H., Laher, G., Balmer, P., Broughton, C., Carrol, E. D., & Borrow, R. (2009). Competitive Inhibition Flow Analysis Assay for the Non-Culture-Based Detection and Serotyping of Pneumococcal Capsular Polysaccharide. CLINICAL AND VACCINE IMMUNOLOGY, 16(2), 222-229. doi:10.1128/CVI.00292-08
Fatal histiocytic proliferative disorders in paediatric HIV infection with cytomegalovirus end-organ disease
Nastouli, E., Carrol, E., Malone, M., Riordan, A., & Lyall, H. (2009). Fatal histiocytic proliferative disorders in paediatric HIV infection with cytomegalovirus end-organ disease. British Journal of Haematology, 146, 573-582.
Tetanus infection.
Cottle, L., Beeching, N. J., Carrol, E. D., & Parry, C. M. (2009). Tetanus infection.. BMJ Point-of-Care.
2008
Bacteremia is associated with a worse outcome in pneumococcal meningitis
Carrol, E. D., Mankhambo, L. A., Corless, C., & Guiver, M. (2008). Bacteremia is associated with a worse outcome in pneumococcal meningitis. JOURNAL OF INFECTIOUS DISEASES, 198(4), 626-627. doi:10.1086/590208
Bacteremia is associated with a worse outcome in pneumococcal meningitis
Carrol, E. D., Mankhambo, L. A., Corless, C., & Guiver, M. (2008). Bacteremia is associated with a worse outcome in pneumococcal meningitis. Journal of Infectious Diseases, 198(626-7).
2007
Successful downstream application of the Paxgene Blood RNA system from small blood samples in paediatric patients for quantitative PCR analysis
Carrol, E. D., Salway, F., Pepper, S. D., Saunders, E., Mankhambo, L. A., Ollier, W. E., . . . Day, P. (2007). Successful downstream application of the Paxgene Blood RNA system from small blood samples in paediatric patients for quantitative PCR analysis. BMC IMMUNOLOGY, 8. doi:10.1186/1471-2172-8-20
High pneumococcal DNA loads are associated with mortality in Malawian children with invasive pneurnococcal disease
Carrol, E. D., Guiver, M., Nkhoma, S., Mankhambo, L. A., Marsh, J., Balmer, P., . . . Hart, C. A. (2007). High pneumococcal DNA loads are associated with mortality in Malawian children with invasive pneurnococcal disease. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 26(5), 416-422. doi:10.1097/01.inf.0000260253.22994.61
Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease
Carrol, E. D., Mankhambo, L. A., Balmer, P., Nkhoma, S., Banda, D. L., Guiver, M., . . . Hart, C. A. (2007). Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 44(4), 443-450. doi:10.1097/QAI.0b013e31802f8390
Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease.
Carrol, E. D., Mankhambo, L. A., Balmer, P., Nkhoma, S., Banda, D. L., Guiver, M., . . . Hart, C. A. (2007). Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease.. J Acquir Immune Defic Syndr. 2007 Apr 1;44(4):443-50, 44((4):), 443-450.
Successful downstream application of the Paxgene Blood RNA system from small blood samples in paediatric patients for quantitative PCR analysis
Carrol, E. D., Salway, F., Pepper, S. D., Saunders, E., Mankhambo, L. A., Ollier, W. E., . . . Day, P. (2007). Successful downstream application of the Paxgene Blood RNA system from small blood samples in paediatric patients for quantitative PCR analysis. BMC Immunology, 8(1), 20. doi:10.1186/1471-2172-8-20
2006
WITHDRAWN: Prospective study of the use of rapid antigen testing in meningococcal disease – an outdated diagnostic test?
Thomson, A. P. J., Hart, C. A., Carrol, E. D., Sills, J., Matwana, N., & Baines, P. (2006). WITHDRAWN: Prospective study of the use of rapid antigen testing in meningococcal disease – an outdated diagnostic test?. Journal of Infection. doi:10.1016/j.jinf.2005.11.084
WITHDRAWN: The role of macrophage migration inhibitory factor in the pathophysiology of meningococcal Disease
Thomson, A. P. J., Hart, C. A., Carrol, E. D., Sills, J., Diver, M., Makwana, N. V., & Baines, P. B. (2006). WITHDRAWN: The role of macrophage migration inhibitory factor in the pathophysiology of meningococcal Disease. Journal of Infection. doi:10.1016/j.jinf.2005.11.058
Clinical and diagnostic findings of an echovirus meningitis outbreak in the north west of England
Carrol, E. D., Beadsworth, M. B. J., Jenkins, N., Ratcliffe, L., Ashton, I., Crowley, B., . . . Beeching, N. J. (2006). Clinical and diagnostic findings of an echovirus meningitis outbreak in the north west of England. POSTGRADUATE MEDICAL JOURNAL, 82(963), 60-64. doi:10.1136/pgmj.2005.036608
Clinical recognition meningococcal disease
Makwana, N., Riordan, F. A. I., Carrol, E. D., Hackett, S. J., Thomson, A. P. J., Baines, P. B., & Hart, C. A. (2006). Clinical recognition meningococcal disease. LANCET, 367(9520), 1394. Retrieved from https://www.webofscience.com/
Persistent visual loss as a complication of meningococcal meningitis
Mankhambo, L. A., Makwana, N. F., Carrol, E. D., Beare, N. A., Taylor, T., Kampondeni, S., & Molyneux, E. M. (2006). Persistent visual loss as a complication of meningococcal meningitis. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 25(6), 566-567. doi:10.1097/01.inf.0000219405.27164.4c
2005
A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis
Carrol, E. D., Thomson, A. P. J., Jones, A. P., Jeffers, G., & Hart, C. A. (2005). A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis. INTENSIVE CARE MEDICINE, 31(10), 1415-1419. doi:10.1007/s00134-005-2787-x
Elevated cytokines in pneumococcal meningitis: Chicken or egg?
Carrol, E. D., & Baines, P. (2005). Elevated cytokines in pneumococcal meningitis: Chicken or egg?. CRITICAL CARE MEDICINE, 33(5), 1153-1154. doi:10.1097/01.CCM.0000162492.74978.77
Chemokine responses in Malawian children with invasive pneumococcal disease
Carrol, E. D., Balmer, P., Nkhoma, S., Mankhambo, L. A., Banda, D. A., Guiver, M., & Hart, C. A. (2005). Chemokine responses in Malawian children with invasive pneumococcal disease. In TISSUE ANTIGENS Vol. 66 (pp. 374). Retrieved from https://www.webofscience.com/
Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the TOPIC study: a randomised controlled trial.
A, S., & et.al., F. T. T. S. G. (2005). Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the TOPIC study: a randomised controlled trial.. Lancet, 365(9459), 573-578. Retrieved from http://dx.doi.org/10.1016/S0140-6736(05)17906-9
Prognostic value of procalcitonin in children with meningococcal sepsis
Carrol, E. D., Newland, P., Thomson, A. P. J., & Hart, C. A. (2005). Prognostic value of procalcitonin in children with meningococcal sepsis. CRITICAL CARE MEDICINE, 33(1), 224-225. doi:10.1097/01.CCM.0000150742.57817.EE
2004
Recombinant tissue plasminogen activator in children with meningococcal purpura fulminans - Role uncertain
Baines, P., & Carrol, E. D. (2004). Recombinant tissue plasminogen activator in children with meningococcal purpura fulminans - Role uncertain. CRITICAL CARE MEDICINE, 32(8), 1806-1807. doi:10.1097/01.CCM.0000133331.07204.46
2003
In meningococcal disease 4G bad, 5G good
Baines, P. B., & Carrol, E. D. (2003). In meningococcal disease 4G bad, 5G good. CRITICAL CARE MEDICINE, 31(12), 2813-2814. doi:10.1097/01.CCM.0000099345.74768.8C
Anhidrotic ectodermal dysplasia and immunodeficiency: the role of NEMO
Carrol, E. D., Gennery, A. R., Flood, T. J., Spickett, G. P., & Abinun, M. (2003). Anhidrotic ectodermal dysplasia and immunodeficiency: the role of NEMO. ARCHIVES OF DISEASE IN CHILDHOOD, 88(4), 340-341. doi:10.1136/adc.88.4.340
Heterogeneity of the syndrome of anhidrotic ectodermal dysplasia associated with immunodeficiency (EDA-ID).
Carrol, E. D., Flood, T. J., Spickett, G. P., Spencer, D. A., Gennery, A. R., & Abinun, M. (2003). Heterogeneity of the syndrome of anhidrotic ectodermal dysplasia associated with immunodeficiency (EDA-ID).. Arch Dis Child 2003;88:340-1, 88(4), 340-341.
2002
Lesson of the week -: <i>Haemophilus influenzae</i> type b epiglottitis as a cause of acute upper airways obstruction in children
Tanner, K., Fitzsimmons, G., Carrol, E. D., Flood, T. J., & Clark, J. E. (2002). Lesson of the week -: <i>Haemophilus influenzae</i> type b epiglottitis as a cause of acute upper airways obstruction in children. BRITISH MEDICAL JOURNAL, 325(7372), 1099-1100. doi:10.1136/bmj.325.7372.1099
Variable number tandem repeat polymorphism of the interleukin-1 receptor antagonist gene in meningococcal disease
Carrol, E. D., Mobbs, K. J., Thomson, A. P. J., & Hart, C. A. (2002). Variable number tandem repeat polymorphism of the interleukin-1 receptor antagonist gene in meningococcal disease. CLINICAL INFECTIOUS DISEASES, 35(4), 495-497. doi:10.1086/341497
Procalcitonin as a marker of sepsis
Carrol, E. D., Thomson, A. P. J., & Hart, C. A. (2002). Procalcitonin as a marker of sepsis. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 20(1), 1-9. doi:10.1016/S0924-8579(02)00047-X
Improved case confirmation in meningococcal disease with whole blood Taqman PCR
Hackett, S. J., Carrol, E. D., Guiver, M., Marsh, J., Sills, J. A., Thomson, A. P. J., . . . Hart, C. A. (2002). Improved case confirmation in meningococcal disease with whole blood Taqman PCR. ARCHIVES OF DISEASE IN CHILDHOOD, 86(6), 449-452. doi:10.1136/adc.86.6.449
Procalcitonin as a diagnostic marker of meningococcal disease in children presenting with fever and a rash
Carrol, E. D., Newland, P., Riordan, F. A. I., Thomson, A. P. J., Curtis, N., & Hart, C. A. (2002). Procalcitonin as a diagnostic marker of meningococcal disease in children presenting with fever and a rash. ARCHIVES OF DISEASE IN CHILDHOOD, 86(4), 282-285. doi:10.1136/adc.86.4.282
Adult echovirus 30 meningitis outbreak
Carrol, E. D., Beadsworth, M., Jenkins, N., Ratcliffe, L., Ashton, I., Crowley, B., . . . Beeching, N. J. (2002). Adult echovirus 30 meningitis outbreak. Journal of Infection, 44(2), 124. doi:10.1016/s0163-4453(02)90350-6
Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease
Carrol, E. D., Mobbs, K. J., Thomson, A. P. J., & Hart, C. A. (2002). Chemokine responses are increased in HIV-infected Malawian children with invasive pneumococcal disease. Clin Inf Dis, 35, 443-450. doi:10.1097/QAI.0b013e31802f8390
Despite immunisation, don't forget Haemophilus influenzae type B (Hib) epiglottitis as a cause of upper airways obstruction in childhood.
Tanner, K., Fitzsimmons, G., Carrol, E. D., Flood, T. J., & Clark, J. E. (2002). Despite immunisation, don't forget Haemophilus influenzae type B (Hib) epiglottitis as a cause of upper airways obstruction in childhood.. BMJ; 2002;325:1099-100, 325(7372), 1099-1100.
Fever in children returning from abroad
Carrol, E. D., & Beeching, N. J. (2002). Fever in children returning from abroad. In Current Paediatrics Vol. 12 (pp. 534-544). Elsevier BV. doi:10.1054/cupe.2002.0356
Myositis in children with meningococcal disease:: A role for tumour necrosis factor-α and interleukin-8?
Carrol, E. D., Thomson, A. P. J., Mobbs, K. J., Fraser, W. D., Sills, J. A., & Hart, C. A. (2002). Myositis in children with meningococcal disease:: A role for tumour necrosis factor-α and interleukin-8?. JOURNAL OF INFECTION, 44(1), 17-21. doi:10.1053/jinf.2001.0923
Procalcitonin as a Diagnostic marker of Meningococcal Disease in Children Presenting with Fever and a Rash.
Carrol, E. D., Newland, P., Riordan, F. A. I., Curtis, N., Thomson, A. P. J., & Hart, C. A. (2002). Procalcitonin as a Diagnostic marker of Meningococcal Disease in Children Presenting with Fever and a Rash.. Arch Dis Child 2002;86:282-285, 86(4), 282-285.
2001
Lesson of the week - Recurrent bacterial meningitis: the need for sensitive imaging
Carrol, E. D., Latif, A. H., Misbah, S. A., Flood, T. J., Abinun, M., Clark, J. E., . . . Cant, A. J. (2001). Lesson of the week - Recurrent bacterial meningitis: the need for sensitive imaging. BRITISH MEDICAL JOURNAL, 323(7311), 501-503. doi:10.1136/bmj.323.7311.501
New therapies and vaccines for meningococcal disease
Carrol, E. D., Thomson, A. P. J., & Hart, C. A. (2001). New therapies and vaccines for meningococcal disease. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 10(8), 1487-1500. doi:10.1517/13543784.10.8.1487
Non-pulmonary tuberculosis.
Carrol, E. D., Clark, J. E., & Cant, A. J. (2001). Non-pulmonary tuberculosis.. Paediatric respiratory reviews, 2(2), 113-119. doi:10.1053/prrv.2000.0118
2000
Performance characteristics of the polymerase chain reaction assay to confirm clinical meningococcal disease
Carrol, E. D., Thomson, A. P. J., Shears, P., Gray, S. J., Kaczmarski, E. B., & Hart, C. A. (2000). Performance characteristics of the polymerase chain reaction assay to confirm clinical meningococcal disease. ARCHIVES OF DISEASE IN CHILDHOOD, 83(3), 271-273. doi:10.1136/adc.83.3.271
The role of RANTES in meningococcal disease
Carrol, E. D., Thomson, A. P. J., Mobbs, K. J., & Hart, C. A. (2000). The role of RANTES in meningococcal disease. JOURNAL OF INFECTIOUS DISEASES, 182(1), 363-366. doi:10.1086/315680
Increasing microbiological confirmation and changing epidemiology of meningococcal disease on Merseyside, England
Carrol, E. D., Thomson, A. P. J., Riordan, F. A. I., Fellick, J. M., Shears, P., Sills, J. A., & Hart, C. A. (2000). Increasing microbiological confirmation and changing epidemiology of meningococcal disease on Merseyside, England. CLINICAL MICROBIOLOGY AND INFECTION, 6(5), 259-262. doi:10.1046/j.1469-0691.2000.00078.x
1999
The role of the Glasgow meningococcal septicaemia prognostic score in the emergency management of meningococcal disease
Carrol, E. D., Riordan, F. A. I., Thomson, A. P. J., Sills, J. A., & Hart, C. A. (1999). The role of the Glasgow meningococcal septicaemia prognostic score in the emergency management of meningococcal disease. ARCHIVES OF DISEASE IN CHILDHOOD, 81(3), 281. Retrieved from https://www.webofscience.com/
Pathophysiology of meningococcal sepsis in children
Carrol, E. D., Baines, P., Thomson, A. P. J., & Hart, C. A. (1999). Pathophysiology of meningococcal sepsis in children. EUROPEAN JOURNAL OF PEDIATRICS, 158(9), 766. doi:10.1007/s004310051198
1996
Congenital lobar emphysema in congenital cytomegalovirus infection
Carrol, E. D., Campbell, M. E., Shaw, B. N. J., & Pilling, D. W. (1996). Congenital lobar emphysema in congenital cytomegalovirus infection. PEDIATRIC RADIOLOGY, 26(12), 900-902. doi:10.1007/BF03178047
1988
DETECTION OF ESTROGEN-RECEPTOR PROTEINS IN BREAST-TUMORS USING AN IMPROVED APAAP IMMUNOHISTOCHEMICAL TECHNIQUE
WONG, S. Y., CARROL, E. D. S., AHSEE, S. Y., & SEWELL, H. F. (1988). DETECTION OF ESTROGEN-RECEPTOR PROTEINS IN BREAST-TUMORS USING AN IMPROVED APAAP IMMUNOHISTOCHEMICAL TECHNIQUE. CANCER, 62(10), 2171-2175. doi:3.0.CO;2-O">10.1002/1097-0142(19881115)62:10<2171::AID-CNCR2820621017>3.0.CO;2-O
Undated
Development of Heart and Respiratory Rate Percentile Curves for Hospitalised Children in the United Kingdom (The DETECT STUDY)
Davies, K., Bracken, A., Lane, S., Olajide, O., Carrol, E., Sefton, G., & Study Group, D. E. T. E. C. T. (n.d.). Development of Heart and Respiratory Rate Percentile Curves for Hospitalised Children in the United Kingdom (The DETECT STUDY).
Relationship Between Molecular Pathogen Detection and Clinical Disease in Febrile Children Across Europe
Shah, P., Voice, M., Calvo-Bado, L., Calle, I. R., Morris, S., Nijman, R., . . . Consortium, P. E. R. F. O. R. M. (n.d.). Relationship Between Molecular Pathogen Detection and Clinical Disease in Febrile Children Across Europe.