Publications
2024
Evidence for the Role of the Mitochondrial ABC Transporter MDL1 in the Uptake of Clozapine and Related Molecules into the Yeast Saccharomyces cerevisiae
Theron, C., Salcedo-Sora, J. E., Grixti, J. M., Moller-Hansen, I., Borodina, I., & Kell, D. B. (2024). Evidence for the Role of the Mitochondrial ABC Transporter MDL1 in the Uptake of Clozapine and Related Molecules into the Yeast Saccharomyces cerevisiae. Pharmaceuticals. doi:10.3390/ph17070938
2022
Role of Dissimilative Pathway of <i>Komagataella phaffii</i> (<i>Pichia pastoris</i>): Formaldehyde Toxicity and Energy Metabolism
Berrios, J., Theron, C. W., Steels, S., Ponce, B., Velastegui, E., Bustos, C., . . . Fickers, P. (2022). Role of Dissimilative Pathway of <i>Komagataella phaffii</i> (<i>Pichia pastoris</i>): Formaldehyde Toxicity and Energy Metabolism. MICROORGANISMS, 10(7). doi:10.3390/microorganisms10071466
2021
Spectral artefacts induced by moving targets in live hyperspectral stimulated Raman spectroscopy: the case of lipid droplets in yeast cells
Lima, C., Theron, C. W., Muhamadali, H., Kell, D. B., & Goodacre, R. (2021). Spectral artefacts induced by moving targets in live hyperspectral stimulated Raman spectroscopy: the case of lipid droplets in yeast cells. Clinical Spectroscopy, 100014. doi:10.1016/j.clispe.2021.100014
2020
Comprehensive comparison of <i>Yarrowia lipolytica</i> and <i>Pichia pastoris</i> for production of <i>Candida antarctica</i> lipase B
Theron, C. W., Vandermies, M., Telek, S., Steels, S., & Fickers, P. (2020). Comprehensive comparison of <i>Yarrowia lipolytica</i> and <i>Pichia pastoris</i> for production of <i>Candida antarctica</i> lipase B. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-58683-3
2019
Heterologous coexpression of the benzoate-para-hydroxylase CYP53B1 with different cytochrome P450 reductases in various yeasts
Theron, C. W., Labuschagne, M., Albertyn, J., & Smit, M. S. (2019). Heterologous coexpression of the benzoate-para-hydroxylase CYP53B1 with different cytochrome P450 reductases in various yeasts. MICROBIAL BIOTECHNOLOGY, 12(6), 1126-1138. doi:10.1111/1751-7915.13321
Organic Wastes as Feedstocks for Non-Conventional Yeast-Based Bioprocesses
Do, D. T. H., Theron, C. W., & Fickers, P. (2019). Organic Wastes as Feedstocks for Non-Conventional Yeast-Based Bioprocesses. MICROORGANISMS, 7(8). doi:10.3390/microorganisms7080229
Regulation of outer-membrane proteins (OMPs) A and F, during <i>hlyF</i>-induced outer-membrane vesicle (OMV) biosynthesis
van der Westhuizen, W. A., Theron, C. W., Boucher, C. E., & Bragg, R. R. (2019). Regulation of outer-membrane proteins (OMPs) A and F, during <i>hlyF</i>-induced outer-membrane vesicle (OMV) biosynthesis. HELIYON, 5(7). doi:10.1016/j.heliyon.2019.e02014
Downregulation by organic nitrogen of <i>AOX1</i> promoter used for controlled expression of foreign genes in the yeast <i>Pichia pastoris</i>
Velastegui, E., Theron, C., Berrios, J., & Fickers, P. (2019). Downregulation by organic nitrogen of <i>AOX1</i> promoter used for controlled expression of foreign genes in the yeast <i>Pichia pastoris</i>. YEAST, 36(5), 297-304. doi:10.1002/yea.3381
Expression of recombinant enhanced green fluorescent protein provides insight into foreign gene-expression differences between Mut plus and MutS strains of <i>Pichia pastoris</i>
Theron, C. W., Berrios, J., Steels, S., Telek, S., Lecler, R., Rodriguez, C., & Fickers, P. (2019). Expression of recombinant enhanced green fluorescent protein provides insight into foreign gene-expression differences between Mut plus and MutS strains of <i>Pichia pastoris</i>. YEAST, 36(5), 285-296. doi:10.1002/yea.3388
Non-Conventional Yeast Species for Recombinant Protein and Metabolite Production
Do, H. D., Vandermies, M., Fickers, P., & Theron, C. W. (2019). Non-Conventional Yeast Species for Recombinant Protein and Metabolite Production. In Reference Module in Life Sciences. Elsevier. doi:10.1016/b978-0-12-809633-8.20885-6
2018
Integrating metabolic modeling and population heterogeneity analysis into optimizing recombinant protein production by <i>Komagataella</i> (<i>Pichia</i>) <i>pastoris</i>
Theron, C. W., Berrios, J., Delvigne, F., & Fickers, P. (2018). Integrating metabolic modeling and population heterogeneity analysis into optimizing recombinant protein production by <i>Komagataella</i> (<i>Pichia</i>) <i>pastoris</i>. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 102(1), 63-80. doi:10.1007/s00253-017-8612-y
The Use of Phage Display and Yeast Based Expression System for the Development of a Von Willebrand Factor Propeptide Assay: Development of a Von Willebrand Factor Propeptide Assay
Meiring, S. M., Setlai, B. D. P., Theron, C., & Bragg, R. (2018). The Use of Phage Display and Yeast Based Expression System for the Development of a Von Willebrand Factor Propeptide Assay: Development of a Von Willebrand Factor Propeptide Assay. BIOMED RESEARCH INTERNATIONAL, 2018. doi:10.1155/2018/6232091
2017
Isolation and characterisation of endocrine disruptor nonylphenol-using bacteria from South Africa
Qhanya, L. B., Mthakathi, N. T., Boucher, C. E., Mashele, S. S., Theron, C. W., & Syed, K. (2017). Isolation and characterisation of endocrine disruptor nonylphenol-using bacteria from South Africa. SOUTH AFRICAN JOURNAL OF SCIENCE, 113(5-6), 39-45. doi:10.17159/sajs.2017/20160287
2016
Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s
Parvez, M., Qhanya, L. B., Mthakathi, N. T., Kgosiemang, I. K. R., Bamal, H. D., Pagadala, N. S., . . . Syed, K. (2016). Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s. SCIENTIFIC REPORTS, 6. doi:10.1038/srep33099
THE POTENTIAL USE OF BACTERIOPHAGE THERAPY AS A TREATMENT OPTION IN A POST-ANTIBIOTIC ERA
Bragg, R. R., Boucher, C. E., van der Westhuizen, W. A., Lee, J. -Y., Coetsee, E., Theron, C., & Meyburgh, L. (2016). THE POTENTIAL USE OF BACTERIOPHAGE THERAPY AS A TREATMENT OPTION IN A POST-ANTIBIOTIC ERA. In ANTIBIOTIC RESISTANCE: MECHANISMS AND NEW ANTIMICROBIAL APPROACHES (pp. 309-328). doi:10.1016/B978-0-12-803642-6.00015-0
Chapter 15 The Potential Use of Bacteriophage Therapy as a Treatment Option in a Post-Antibiotic Era
Bragg, R. R., Boucher, C. E., van der Westhuizen, W. A., Lee, J. -Y., Coetsee, E., Theron, C., & Meyburgh, L. (2016). Chapter 15 The Potential Use of Bacteriophage Therapy as a Treatment Option in a Post-Antibiotic Era. In Antibiotic Resistance (pp. 309-328). Elsevier. doi:10.1016/b978-0-12-803642-6.00015-0
Front-matter
Front-matter (2016). In Antibiotic Resistance (pp. i-iii). Elsevier. doi:10.1016/b978-0-12-803642-6.00019-8
2015
Regulation of chicken immunity-related genes and host response profiles against <i>Avibacterium paragallinarum</i> pathogen challenge
Boucher, C. E., Theron, C. W., Hitzeroth, A. C., & Bragg, R. R. (2015). Regulation of chicken immunity-related genes and host response profiles against <i>Avibacterium paragallinarum</i> pathogen challenge. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 167(1-2), 70-74. doi:10.1016/j.vetimm.2015.06.005
2014
Transcriptional profiling of chicken immunity-related genes during infection with <i>Avibacterium paragallinarum</i>
Boucher, C. E., Theron, C. W., Jansen, A. C., & Bragg, R. R. (2014). Transcriptional profiling of chicken immunity-related genes during infection with <i>Avibacterium paragallinarum</i>. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 158(3-4), 135-142. doi:10.1016/j.vetimm.2013.12.004
A broad-range yeast expression system reveals Arxula adeninivorans expressing a fungal self-sufficient cytochrome P450 monooxygenase as an excellent whole-cell biocatalyst
Theron, C. W., Labuschagne, M., Gudiminchi, R., Albertyn, J., & Smit, M. S. (2014). A broad-range yeast expression system reveals Arxula adeninivorans expressing a fungal self-sufficient cytochrome P450 monooxygenase as an excellent whole-cell biocatalyst. FEMS YEAST RESEARCH, 14(4), 556-566. doi:10.1111/1567-1364.12142