Publications
2024
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., . . . Rentería, M. E. (2024). Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.. Nature genetics. doi:10.1038/s41588-024-01951-z
Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system.
Wu, L., Fu, X., Pütz, B., Zhang, R., Liu, L., Song, W., . . . Chen, J. (2024). Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system.. Infection, 52(5), 1875-1887. doi:10.1007/s15010-024-02237-6
Fine-mapping genomic loci refines bipolar disorder risk genes.
Koromina, M., Ravi, A., Panagiotaropoulou, G., Schilder, B. M., Humphrey, J., Braun, A., . . . Mullins, N. (2024). Fine-mapping genomic loci refines bipolar disorder risk genes.. medRxiv. doi:10.1101/2024.02.12.24302716
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla, L., Dolgalev, G., Moser, S., Jiménez-Barrón, L. T., Andlauer, T. F. M., von Scheidt, M., . . . Ziller, M. J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases.. Nature communications, 15(1), 5534. doi:10.1038/s41467-024-49338-2
HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study.
Qu, K., Li, M. -X., Yu, P., International Headache Genetics Consortium., Wu, B. -H., Shi, M., & Dong, M. (2024). HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study.. Scientific reports, 14(1), 12094. doi:10.1038/s41598-024-61628-9
Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease.
Li, L., Pang, S., Starnecker, F., Mueller-Myhsok, B., & Schunkert, H. (2024). Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease.. European heart journal, 45(20), 1843-1852. doi:10.1093/eurheartj/ehae048
Correction: Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system.
Wu, L., Fu, X., Pütz, B., Zhang, R., Liu, L., Song, W., . . . Chen, J. (2024). Correction: Comprehensive risk factor predictions for 3-year survival among HIV-associated and disseminated cryptococcosis involving lungs and central nervous system.. Infection. doi:10.1007/s15010-024-02281-2
Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis.
Dong, M. S., Rokicki, J., Dwyer, D., Papiol, S., Streit, F., Rietschel, M., . . . Koutsouleris, N. (2024). Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis.. Translational psychiatry, 14(1), 196. doi:10.1038/s41398-024-02903-1
Sex-specific fear acquisition following early life stress is linked to amygdala glutamate metabolism
Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
Panagiotaropoulou, G., Hellberg, K. -L. G., Coleman, J. R. I., Seok, D., Kalman, J., Bipolar Disorder Working Group of the Psychiatric Genetics Consortium., . . . Loohuis, L. O. (2024). Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.. medRxiv. doi:10.1101/2024.01.29.24301816
Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study.
Li, G., Duan, S., International Headache Genetics Consortium (IHGC)., Zheng, T., Zhu, T., Qu, B., . . . Liu, Z. (2024). Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study.. Frontiers in immunology, 15, 1376698. doi:10.3389/fimmu.2024.1376698
Genome-Wide Association Study in 2,140 Patients and Subtype Meta-analyses of Barlow’s Disease and Fibroelastic Deficiency Identify Novel Risk Loci for Mitral Valve Prolapse
Feirer, N., Weber, M., Knoll, K., Miranda, L., Yu, M., Lahm, H., . . . Dreßen, M. (2024). Genome-Wide Association Study in 2,140 Patients and Subtype Meta-analyses of Barlow’s Disease and Fibroelastic Deficiency Identify Novel Risk Loci for Mitral Valve Prolapse. In The Thoracic and Cardiovascular Surgeon. Georg Thieme Verlag KG. doi:10.1055/s-0044-1780571
Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.
Adams, M. J., Thorp, J. G., Jermy, B. S., Kwong, A. S. F., Kõiv, K., Grotzinger, A. D., . . . Derks, E. M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.. Psychological medicine, 54(12), 3459-3468. doi:10.1017/s0033291724001880
2023
netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity.
Li, Z., Melograna, F., Hoskens, H., Duroux, D., Marazita, M. L., Walsh, S., . . . Van Steen, K. (2023). netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity.. Frontiers in genetics, 14, 1286800. doi:10.3389/fgene.2023.1286800
Genomics yields biological and phenotypic insights into bipolar disorder
14. COORDINATED EPISTASIS REVEALS SYMPTOM-SPECIFIC POLYGENIC PATHWAY INTERACTIONS IN MAJOR DEPRESSIVE DISORDER
Rietkerk, J., Huang, L., Appadurai, V., Pons, V. T., van Loo, H., Garvert, L., . . . Cai, N. (2023). 14. COORDINATED EPISTASIS REVEALS SYMPTOM-SPECIFIC POLYGENIC PATHWAY INTERACTIONS IN MAJOR DEPRESSIVE DISORDER. European Neuropsychopharmacology, 75, S63-S64. doi:10.1016/j.euroneuro.2023.08.125
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent <i>NRXN1</i> and <i>ABCB11</i> disruptions.
Maury, E. A., Sherman, M. A., Genovese, G., Gilgenast, T. G., Kamath, T., Burris, S. J., . . . Walsh, C. A. (2023). Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent <i>NRXN1</i> and <i>ABCB11</i> disruptions.. Cell genomics, 3(8), 100356. doi:10.1016/j.xgen.2023.100356
Burnout and secondary traumatic stress in staff working with people with intellectual disabilities: The role of adverse childhood experiences, resilience and trauma-informed organisational climate
Mercer, L., Cookson, A., Mueller-Myhsok, B., & van Vuuren, J. (2023). Burnout and secondary traumatic stress in staff working with people with intellectual disabilities: The role of adverse childhood experiences, resilience and trauma-informed organisational climate. JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES. doi:10.1111/jar.13148
Migraine, chronic kidney disease and kidney function: observational and genetic analyses.
Zhang, W., Zhang, L., Yang, L., Xiao, C., Wu, X., Yan, P., . . . International Headache Genetics Consortium. (2023). Migraine, chronic kidney disease and kidney function: observational and genetic analyses.. Human genetics, 142(8), 1185-1200. doi:10.1007/s00439-023-02575-9
Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress
Bordes, J., Miranda, L., Reinhardt, M., Narayan, S., Hartmann, J., Newman, E. L., . . . Schmidt, M. V. (2023). Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress. NATURE COMMUNICATIONS, 14(1). doi:10.1038/s41467-023-40040-3
A causal effects of gut microbiota in the development of migraine.
He, Q., Wang, W., Xiong, Y., Tao, C., Ma, L., Ma, J., . . . International Headache Genetics Consortium. (2023). A causal effects of gut microbiota in the development of migraine.. The journal of headache and pain, 24(1), 90. doi:10.1186/s10194-023-01609-x
Genetic structure of major depression symptoms across clinical and community cohorts.
Adams, M. J., Thorp, J. G., Jermy, B. S., Kwong, A. S. F., Kõiv, K., Grotzinger, A. D., . . . Derks, E. M. (2023). Genetic structure of major depression symptoms across clinical and community cohorts.. medRxiv. doi:10.1101/2023.07.05.23292214
Polygenic risk prediction: why and when out-of-sample prediction R<sup>2</sup> can exceed SNP-based heritability.
Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M., . . . Wray, N. R. (2023). Polygenic risk prediction: why and when out-of-sample prediction R<sup>2</sup> can exceed SNP-based heritability.. American journal of human genetics, 110(7), 1207-1215. doi:10.1016/j.ajhg.2023.06.006
High genetic risk for depression as an independent risk factor for mortality in patients referred for coronary angiography
Kraemer, R. M. M., Moissl, A. P. P., Lorkowski, S., Kraemer, B. K. K., Lehtimaeki, T., Mishra, B. H. H., . . . Delgado, G. E. E. (2023). High genetic risk for depression as an independent risk factor for mortality in patients referred for coronary angiography. FRONTIERS IN CARDIOVASCULAR MEDICINE, 10. doi:10.3389/fcvm.2023.1125151
DeepOF: a Python package for supervised and unsupervised pattern recognition in mice motion tracking data
Miranda, L., Bordes, J., Pütz, B., Schmidt, M. V., & Müller-Myhsok, B. (2023). DeepOF: a Python package for supervised andunsupervised pattern recognition in mice motion tracking data. Journal of Open Source Software, 8(86), 5394. doi:10.21105/joss.05394
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes
Yu, M., Aguirre, M., Jia, M., Gjoni, K., Cordova-Palomera, A., Munger, C., . . . Priest, J. R. (2023). Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes. CIRCULATION-GENOMIC AND PRECISION MEDICINE, 16(3), 258-266. doi:10.1161/CIRCGEN.122.003968
Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning
Bordes, J., Miranda, L., Mueller-Myhsok, B., & Schmidt, M. V. (2023). Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 151. doi:10.1016/j.neubiorev.2023.105243
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.
Hsu, Y. -H. H., Pintacuda, G., Liu, R., Nacu, E., Kim, A., Tsafou, K., . . . Lage, K. (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.. iScience, 26(5), 106701. doi:10.1016/j.isci.2023.106701
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla, L., Moser, S., Jiménez-Barrón, L. T., Andlauer, T. F. M., von Scheidt, M., Schizophrenia Working Group of the Psychiatric Genomics Consortium., . . . Ziller, M. J. (2023). Distinct genetic liability profiles define clinically relevant patient strata across common diseases.. medRxiv. doi:10.1101/2023.05.10.23289788
netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity
Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study.
Welander, N. Z., Rukh, G., Rask-Andersen, M., Harder, A. V. E., International Headache Genetics Consortium., van den Maagdenberg, A. M. J. M., . . . Mwinyi, J. (2023). Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study.. Headache, 63(5), 642-651. doi:10.1111/head.14470
Author Correction: Discovery of 42 genome-wide significant loci associated with dyslexia.
Doust, C., Fontanillas, P., Eising, E., Gordon, S. D., Wang, Z., Alagöz, G., . . . Luciano, M. (2023). Author Correction: Discovery of 42 genome-wide significant loci associated with dyslexia.. Nature genetics, 55(3), 520. doi:10.1038/s41588-023-01336-8
Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.
Bakker, M. K., Kanning, J. P., Abraham, G., Martinsen, A. E., Winsvold, B. S., Zwart, J. -A., . . . HUNT All-In Stroke, CADISP group, International Consortium for Blood Pressure, International Headache Genetics Consortium, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group. (2023). Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.. Stroke, 54(3), 810-818. doi:10.1161/strokeaha.122.040715
Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder
Hahn, T., Winter, N. R., Ernsting, J., Gruber, M., Mauritz, M. J., Fisch, L., . . . Repple, J. (2023). Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder. MOLECULAR PSYCHIATRY, 28(3), 1057-1063. doi:10.1038/s41380-022-01936-6
Causal relationships between migraine and microstructural white matter: a Mendelian randomization study.
Zhao, L., Zhao, W., International Headache Genetics Consortium (IHGC)., Cao, J., & Tu, Y. (2023). Causal relationships between migraine and microstructural white matter: a Mendelian randomization study.. The journal of headache and pain, 24(1), 10. doi:10.1186/s10194-023-01550-z
Genetic and modifiable risk factors combine multiplicatively in common disease
Pang, S., Yengo, L., Nelson, C. P., Bourier, F., Zeng, L., Li, L., . . . Schunkert, H. (2022). Genetic and modifiable risk factors combine multiplicatively in common disease. CLINICAL RESEARCH IN CARDIOLOGY. doi:10.1007/s00392-022-02081-4
2022
Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities
Price, K. M., Wigg, K. G., Eising, E., Feng, Y., Blokland, K., Wilkinson, M., . . . Barr, C. L. (2022). Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities. TRANSLATIONAL PSYCHIATRY, 12(1). doi:10.1038/s41398-022-02250-z
Discovery of 42 genome-wide significant loci associated with dyslexia
Doust, C., Fontanillas, P., Eising, E., Gordon, S. D., Wang, Z., Alagöz, G., . . . Luciano, M. (2022). Discovery of 42 genome-wide significant loci associated with dyslexia. Nature Genetics, 54(11), 1621-1629. doi:10.1038/s41588-022-01192-y
BICLUSTERING ALGORITHM APPLIED TO STRUCTURAL MAGNETIC RESONANCE IMAGING IN MAJOR DEPRESSIVE DISORDER
Panzenhagen, A., Schmaal, L., Czisch, M., Mueller-Myhsok, B., & Samann, P. (2022). BICLUSTERING ALGORITHM APPLIED TO STRUCTURAL MAGNETIC RESONANCE IMAGING IN MAJOR DEPRESSIVE DISORDER. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 63 (pp. E170). doi:10.1016/j.euroneuro.2022.07.309
COORDINATED EPISTASIS REVEALS SYMPTOM-DRIVEN PATHWAYS TOWARDS MAJOR DEPRESSIVE DISORDER
Rietkerk, J., Huang, L., Appadurai, V., Krebs, M., Werge, T., Schork, A., . . . Cai, N. (2022). COORDINATED EPISTASIS REVEALS SYMPTOM-DRIVEN PATHWAYS TOWARDS MAJOR DEPRESSIVE DISORDER. European Neuropsychopharmacology, 63, e267. doi:10.1016/j.euroneuro.2022.07.476
Elucidating the relationship between migraine risk and brain structure using genetic data.
Mitchell, B. L., Diaz-Torres, S., Bivol, S., Cuellar-Partida, G., International Headache Genetics Consortium., Gerring, Z. F., . . . Rentería, M. E. (2022). Elucidating the relationship between migraine risk and brain structure using genetic data.. Brain : a journal of neurology, 145(9), 3214-3224. doi:10.1093/brain/awac105
Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.
Eising, E., Mirza-Schreiber, N., de Zeeuw, E. L., Wang, C. A., Truong, D. T., Allegrini, A. G., . . . Fisher, S. E. (2022). Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.. Proceedings of the National Academy of Sciences of the United States of America, 119(35), e2202764119. doi:10.1073/pnas.2202764119
Creating sparser prediction models of treatment outcome in depression: a proof-of-concept study using simultaneous feature selection and hyperparameter tuning
Rost, N., Bruckl, T. M., Koutsouleris, N., Binder, E. B., & Mueller-Myhsok, B. (2022). Creating sparser prediction models of treatment outcome in depression: a proof-of-concept study using simultaneous feature selection and hyperparameter tuning. BMC MEDICAL INFORMATICS AND DECISION MAKING, 22(1). doi:10.1186/s12911-022-01926-2
Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors
Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress
ExomeChip-based rare variant association study in restless legs syndrome
Tilch, E., Schormair, B., Zhao, C., Hoegl, B., Stefani, A., Berger, K., . . . Winkelmann, J. (2022). ExomeChip-based rare variant association study in restless legs syndrome. SLEEP MEDICINE, 94, 26-30. doi:10.1016/j.sleep.2022.04.001
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V., Pardinas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., . . . O'Donovan, M. C. (2022). Mapping genomic loci implicates genes and synaptic biology in schizophrenia. NATURE, 604(7906), 502-508. doi:10.1038/s41586-022-04434-5
Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects.
Nenadić, I., Meller, T., Schmitt, S., Stein, F., Brosch, K., Mosebach, J., . . . Kircher, T. (n.d.). Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects.. Psychological medicine. doi:10.1017/s0033291720002822
Identifying the Common Genetic Basis of Antidepressant Response.
Pain, O., Hodgson, K., Trubetskoy, V., Ripke, S., Marshe, V. S., Adams, M. J., . . . Lewis, C. M. (2022). Identifying the Common Genetic Basis of Antidepressant Response.. Biological psychiatry global open science, 2(2), 115-126. doi:10.1016/j.bpsgos.2021.07.008
<i>Cis</i>-epistasis at the <i>LPA</i> locus and risk of cardiovascular diseases
Zeng, L., Moser, S., Mirza-Schreiber, N., Lamina, C., Coassin, S., Nelson, C. P., . . . Schunkert, H. (2022). <i>Cis</i>-epistasis at the <i>LPA</i> locus and risk of cardiovascular diseases. CARDIOVASCULAR RESEARCH, 118(4), 1088-1102. doi:10.1093/cvr/cvab136
GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating alpha-Klotho levels
Gergei, I., Zheng, J., Andlauer, T. F. M., Brandenburg, V., Mirza-Schreiber, N., Mueller-Myhsok, B., . . . Tobias, J. H. (2022). GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating alpha-Klotho levels. HUMAN MOLECULAR GENETICS, 31(5), 792-802. doi:10.1093/hmg/ddab263
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas, A. F., Smart, S. E., Willcocks, I. R., Holmans, P. A., Dennison, C. A., Lynham, A. J., . . . Vázquez-Bourgon, J. (2022). Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.. JAMA psychiatry, 79(3), 260-269. doi:10.1001/jamapsychiatry.2021.3799
DNA-methylation dynamics across short-term, exposure-containing CBT in patients with panic disorder
Moser, S., Martins, J., Czamara, D., Lange, J., Mueller-Myhsok, B., & Erhardt, A. (2022). DNA-methylation dynamics across short-term, exposure-containing CBT in patients with panic disorder. TRANSLATIONAL PSYCHIATRY, 12(1). doi:10.1038/s41398-022-01802-7
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., . . . Ruderfer, D. M. (2022). Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. BIOLOGICAL PSYCHIATRY, 91(3), 313-327. doi:10.1016/j.biopsych.2021.05.029
Genome and transcriptome profiling of spontaneous preterm birth phenotypes (vol 12, 1003, 2022)
Gupta, J. K., Care, A., Goodfellow, L., Alfirevic, Z., Muller-Myhsok, B., & Alfirevic, A. (2022). Genome and transcriptome profiling of spontaneous preterm birth phenotypes (vol 12, 1003, 2022). SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-06338-w
Genome and transcriptome profiling of spontaneous preterm birth phenotypes
Gupta, J. K., Care, A., Goodfellow, L., Alfirevic, Z., Muller-Myhsok, B., & Alfirevic, A. (2022). Genome and transcriptome profiling of spontaneous preterm birth phenotypes. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-04881-0
Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol
Fontana, V., Turner, R. M., Francis, B., Yin, P., Puetz, B., Hiltunen, T. P., . . . Pirmohamed, M. (2022). Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol. PHARMACOGENOMICS & PERSONALIZED MEDICINE, 15, 249-260. doi:10.2147/PGPM.S352719
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. -Y., Cotsapas, C., Tobet, S., Handa, R., . . . Goldstein, J. M. (2022). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. BIOLOGICAL PSYCHIATRY, 91(1), 102-117. doi:10.1016/j.biopsych.2021.02.972
2021
Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation
Moore, S. R., Halldorsdottir, T., Martins, J., Lucae, S., Mueller-Myhsok, B., Mueller, N. S., . . . Arloth, J. (2021). Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. TRANSLATIONAL PSYCHIATRY, 11(1). doi:10.1038/s41398-021-01756-2
Characterisation of age and polarity at onset in bipolar disorder
Kalman, J. L., Loohuis, L. M. O., Vreeker, A., McQuillin, A., Stahl, E. A., Ruderfer, D., . . . Ophoff, R. A. (2021). Characterisation of age and polarity at onset in bipolar disorder. BRITISH JOURNAL OF PSYCHIATRY, 219(6), 659-669. doi:10.1192/bjp.2021.102
Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study
Goodfellow, L., Verwijs, M. C., Care, A., Sharp, A., Ivandic, J., Poljak, B., . . . van de Wijgert, J. H. H. M. (2021). Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 128(13), 2061-2072. doi:10.1111/1471-0528.16816
Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., . . . Wray, N. R. (2021). A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.. Biological psychiatry, 90(9), 611-620. doi:10.1016/j.biopsych.2021.04.018
The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.
Giannakopoulou, O., Lin, K., Meng, X., Su, M. -H., Kuo, P. -H., Peterson, R. E., . . . 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. (2021). The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study.. JAMA psychiatry, 78(11), 1258-1269. doi:10.1001/jamapsychiatry.2021.2099
Systematic Review of Functional MRI Applications for Psychiatric Disease Subtyping
Miranda, L., Paul, R., Puetz, B., Koutsouleris, N., & Mueller-Myhsok, B. (2021). Systematic Review of Functional MRI Applications for Psychiatric Disease Subtyping. FRONTIERS IN PSYCHIATRY, 12. doi:10.3389/fpsyt.2021.665536
Association and genetic overlap between clinical chemistry tests and migraine.
Tanha, H. M., Martin, N. G., Whitfield, J. B., Nyholt, D. R., & International Headache Genetics Consortium (IHGC). (2021). Association and genetic overlap between clinical chemistry tests and migraine.. Cephalalgia : an international journal of headache, 41(11-12), 1208-1221. doi:10.1177/03331024211018131
Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning
Pelin, H., Ising, M., Stein, F., Meinert, S., Meller, T., Brosch, K., . . . Andlauer, T. F. M. (2021). Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning. NEUROPSYCHOPHARMACOLOGY, 46(11), 1895-1905. doi:10.1038/s41386-021-01051-0
Metabolic profiling of maternal serum of women a high-risk of spontaneous preterm birth using NMR and MGWAS approach
Gupta, J. K., Care, A., Goodfellow, L., Alfirevic, Z., Lian, L. -Y., Mueller-Myhsok, B., . . . Phelan, M. M. (2021). Metabolic profiling of maternal serum of women a high-risk of spontaneous preterm birth using NMR and MGWAS approach. BIOSCIENCE REPORTS, 41(9). doi:10.1042/BSR20210759
Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., . . . Breen, G. (2021). Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.. Molecular psychiatry, 26(9), 5465. doi:10.1038/s41380-020-0779-4
Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: a nested case control study
Care, A. G., Gupta, J. K., Goodfellow, L., Zhang, G., Monangi, N., Belling, E., . . . Alfirevic, Z. (2021). Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: a nested case control study. European Journal of Obstetrics & Gynecology and Reproductive Biology. doi:10.1016/j.ejogrb.2021.08.015
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression
Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., . . . Schumacher, J. (2021). Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. MOLECULAR PSYCHIATRY, 26(8), 4179-4190. doi:10.1038/s41380-019-0590-2
Plasma long-chain omega-3 fatty acid status and risk of recurrent early spontaneous preterm birth: a prospective observational study
Goodfellow, L., Care, A., Harrold, J., Sharp, A., Ivandic, J., Poljak, B., . . . Alfirevic, Z. (2021). Plasma long-chain omega-3 fatty acid status and risk of recurrent early spontaneous preterm birth: a prospective observational study. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 100(8), 1401-1411. doi:10.1111/aogs.14147
A Network Control Theory Approach to Longitudinal Symptom Dynamics in Major Depressive Disorder
Genetic, Individual, and Familial Risk Correlates of Brain Network Controllability in Major Depressive Disorder
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity (vol 188, e2018457118, 2020)
Ostkamp, P., Salmen, A., Pignolet, B., Gorlich, D., Andlauer, T. F. M., Schulte-Mecklenbeck, A., . . . Schwab, N. (2021). Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity (vol 188, e2018457118, 2020). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(29). doi:10.1073/pnas.2110306118
Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia
Gialluisi, A., Andlauer, T. F. M., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., . . . Schulte-Koerne, G. (2021). Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia. MOLECULAR PSYCHIATRY, 26(7), 3004-3017. doi:10.1038/s41380-020-00898-x
Novel EDGE encoding method enhances ability to identify genetic interactions
Hall, M. A., Wallace, J., Lucas, A. M., Bradford, Y., Verma, S. S., Mueller-Myhsok, B., . . . Ritchie, M. D. (2021). Novel EDGE encoding method enhances ability to identify genetic interactions. PLOS GENETICS, 17(6). doi:10.1371/journal.pgen.1009534
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., . . . Baune, B. T. (2021). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.. Molecular psychiatry, 26(6), 2457-2470. doi:10.1038/s41380-020-0689-5
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., . . . Andreassen, O. A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. NATURE GENETICS, 53(6), 817-+. doi:10.1038/s41588-021-00857-4
The association between genetically determined ABO blood types and major depressive disorder
Garvert, L., Baune, B. T., Berger, K., Boomsma, D. I., Breen, G., Greinacher, A., . . . Van der Auwera, S. (2021). The association between genetically determined ABO blood types and major depressive disorder. PSYCHIATRY RESEARCH, 299. doi:10.1016/j.psychres.2021.113837
Interaction of developmental factors and ordinary stressful life events on brain structure in adults
Ringwald, K. G., Meller, T., Schmitt, S., Andlauer, T. F. M., Stein, F., Brosch, K., . . . Kircher, T. (2021). Interaction of developmental factors and ordinary stressful life events on brain structure in adults. NEUROIMAGE-CLINICAL, 30. doi:10.1016/j.nicl.2021.102683
Characterization of Age and Polarity at Onset in Bipolar Disorder
Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity
Schmitt, S., Meller, T., Stein, F., Brosch, K., Ringwald, K., Pfarr, J. -K., . . . Nenadic, I. (2022). Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity. PSYCHOLOGICAL MEDICINE, 52(16), 4127-4138. doi:10.1017/S0033291721001082
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., Gonzalez, M. J., Gil Flores, S., . . . Rietschel, M. (2021). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. MOLECULAR PSYCHIATRY, 26(4), 1286-1298. doi:10.1038/s41380-019-0558-2
Genetic factors influencing a neurobiological substrate for psychiatric disorders
Andlauer, T. F. M., Muehleisen, T. W., Hoffstaedter, F., Teumer, A., Wittfeld, K., Teuber, A., . . . Cichon, S. (2021). Genetic factors influencing a neurobiological substrate for psychiatric disorders. TRANSLATIONAL PSYCHIATRY, 11(1). doi:10.1038/s41398-021-01317-7
"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment
Heilbronner, U., Papiol, S., Budde, M., Andlauer, T. F. M., Strohmaier, J., Streit, F., . . . Schulze, T. G. (2021). "The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 186(2), 77-89. doi:10.1002/ajmg.b.32837
A polygenic resilience score moderates the genetic risk for schizophrenia.
Hess, J. L., Tylee, D. S., Mattheisen, M., Schizophrenia Working Group of the Psychiatric Genomics Consortium., Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH)., Børglum, A. D., . . . Glatt, S. J. (2021). A polygenic resilience score moderates the genetic risk for schizophrenia.. Molecular psychiatry, 26(3), 800-815. doi:10.1038/s41380-019-0463-8
Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning
Congenital heart disease risk loci identified by genome-wide association study in European patients
Lahm, H., Jia, M., Dressen, M., Wirth, F., Puluca, N., Gilsbach, R., . . . Krane, M. (2021). Congenital heart disease risk loci identified by genome-wide association study in European patients. JOURNAL OF CLINICAL INVESTIGATION, 131(2). doi:10.1172/JCI141837
Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study
Goodfellow, L., Verwijs, M., Care, A., Sharp, A., Ivandic, J., Poljak, B., . . . van de Wijgert, J. H. H. M. (2021). Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study. doi:10.1101/2021.01.14.21249680
Adapting the randomised controlled trial (RCT) for precision medicine: introducing the nested-precision RCT (npRCT)
Kappelmann, N., Mueller-Myhsok, B., & Kopf-Beck, J. (2021). Adapting the randomised controlled trial (RCT) for precision medicine: introducing the nested-precision RCT (npRCT). TRIALS, 22(1). doi:10.1186/s13063-020-04965-0
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity
Ostkamp, P., Salmen, A., Pignolet, B., Goerlich, D., Andlauer, T. F. M., Schulte-Mecklenbeck, A., . . . Schwab, N. (2021). Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(1). doi:10.1073/pnas.2018457118
A Network Control Theory Approach to Longitudinal Symptom Dynamics in Major Depressive Disorder.
Hahn, T., Jamalabadi, H., Emden, D., Goltermann, J., Ernsting, J., Winter, N. R., . . . Opel, N. (2021). A Network Control Theory Approach to Longitudinal Symptom Dynamics in Major Depressive Disorder.. CoRR, abs/2107.10178.
Functional Analysis of Candidate Genes Associated with Congenital Heart Disease during Differentiation of Induced Pluripotent Stem Cells and in the Human Embryonic and Adult Heart at Single-Cell Resolution
Lahm, H., Wirth, F., Dreßen, M., Jia, M., Puluca, N., Cleuziou, J., . . . Krane, M. (2021). Functional Analysis of Candidate Genes Associated with Congenital Heart Disease during Differentiation of Induced Pluripotent Stem Cells and in the Human Embryonic and Adult Heart at Single-Cell Resolution. In The Thoracic and Cardiovascular Surgeon. Georg Thieme Verlag KG. doi:10.1055/s-0041-1725667
Identification of early pregnancy metabolomic biomarkers of women at high-risk of preterm birth using NMR and mGWAS
Gupta, J., Care, A., Goodfellow, L., Alfirevic, Z., Lian, L. -Y., Muller-Myhsok, B., . . . Phelan, M. (2021). Identification of early pregnancy metabolomic biomarkers of women at high-risk of preterm birth using NMR and mGWAS. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 178 (pp. 432-433). Retrieved from https://www.webofscience.com/
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. -L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., . . . Agrawal, A. (2021). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. ADDICTION BIOLOGY, 26(1). doi:10.1111/adb.12880
2020
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., . . . Debette, S. (2020). Cerebral small vessel disease genomics and its implications across the lifespan.. Nature communications, 11(1), 6285. doi:10.1038/s41467-020-19111-2
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors
A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., . . . Agrawal, A. (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder.. The lancet. Psychiatry, 7(12), 1032-1045. doi:10.1016/s2215-0366(20)30339-4
Habitual sleep disturbances and migraine: a Mendelian randomization study.
Daghlas, I., Vgontzas, A., Guo, Y., Chasman, D. I., International Headache Genetics Consortium., & Saxena, R. (2020). Habitual sleep disturbances and migraine: a Mendelian randomization study.. Annals of clinical and translational neurology, 7(12), 2370-2380. doi:10.1002/acn3.51228
Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease
Gola, D., Erdmann, J., Lall, K., Magi, R., Muller-Myhsok, B., Schunkert, H., & Konig, I. R. (2020). Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease. In CIRCULATION-GENOMIC AND PRECISION MEDICINE Vol. 13 (pp. 569-575). doi:10.1161/CIRCGEN.120.002932
Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS
Andlauer, T. F. M., Link, J., Martin, D., Ryner, M., Hermanrud, C., Grummel, V., . . . Hemmer, B. (2020). Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. BMC MEDICINE, 18(1). doi:10.1186/s12916-020-01769-6
A Novel Locus and Candidate Gene for Familial Developmental Dyslexia on Chromosome 4q
Grimm, T., Garshasbi, M., Puettmann, L., Chen, W., Ullmann, R., Muller-Myhsok, B., . . . Kuss, A. W. (2020). A Novel Locus and Candidate Gene for Familial Developmental Dyslexia on Chromosome 4q. ZEITSCHRIFT FUR KINDER-UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE, 48(6), 478-489. doi:10.1024/1422-4917/a000758
Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.
Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., . . . Seshadri, S. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.. Nature communications, 11(1), 4796. doi:10.1038/s41467-020-18367-y
Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes
Faber, H., Kurtoic, D., Krishnamoorthy, G., Weber, P., Puetz, B., Mueller-Myhsok, B., . . . Andlauer, T. F. M. (2020). Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes. FRONTIERS IN IMMUNOLOGY, 11. doi:10.3389/fimmu.2020.02165
Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology
Investigation of gene-gene interactions in cardiac traits and serum fatty acid levels in the LURIC Health Study
Zhou, J., Passero, K., Palmiero, N. E., Mueller-Myhsok, B., Kleber, M. E., Maerz, W., & Hall, M. A. (2020). Investigation of gene-gene interactions in cardiac traits and serum fatty acid levels in the LURIC Health Study. PLOS ONE, 15(9). doi:10.1371/journal.pone.0238304
Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity
Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression
Hagenaars, S. P., Coleman, J. R. I., Choi, S. W., Gaspar, H., Adams, M. J., Howard, D. M., . . . Lewis, C. M. (2020). Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 183(6), 309-330. doi:10.1002/ajmg.b.32807
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., & Breen, G. (2019). The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.. Biological psychiatry. doi:10.1016/j.biopsych.2019.10.015
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.
Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., International Headache Genetics Consortium., 23andMe Research Team., . . . Chasman, D. I. (2020). A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.. Nature communications, 11(1). doi:10.1038/s41467-020-17002-0
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., . . . Sullivan, P. F. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. MOLECULAR PSYCHIATRY, 25(7), 1430-1446. doi:10.1038/s41380-019-0546-6
Functional MRI applications for psychiatric disease subtyping: a review
Complement genes contribute sex-biased vulnerability in diverse disorders.
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., . . . McCarroll, S. A. (2020). Complement genes contribute sex-biased vulnerability in diverse disorders.. Nature, 582(7813), 577-581. doi:10.1038/s41586-020-2277-x
Genome-wide association study in European patients with congenital heart disease identifies risk loci for transposition of the great arteries and anomalies of the thoracic arteries and veins and expression of discovered candidate genes in the developing heart
Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache.
Siewert, K. M., Klarin, D., Damrauer, S. M., Chang, K. -M., Tsao, P. S., Assimes, T. L., . . . The International Headache Genetics Consortium. (2020). Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache.. International journal of epidemiology, 49(3), 1022-1031. doi:10.1093/ije/dyaa050
Salivary cortisol response to psychosocial stress in the late evening depends on <i>CRHR1</i> genotype
Weeger, J., Ising, M., Mueller-Myhsok, B., Uhr, M., Schmidt, U., & Steiger, A. (2020). Salivary cortisol response to psychosocial stress in the late evening depends on <i>CRHR1</i> genotype. PSYCHONEUROENDOCRINOLOGY, 116. doi:10.1016/j.psyneuen.2020.104685
S13. IMPACT OF POLYGENIC AND POLY-ENVIRONMENTAL RISK FACTORS ON A PSYCHOSIS RISK PHENOTYPE EXPLAINED THROUGH BRAIN STRUCTURE
Meller, T., Schmitt, S., Stein, F., Brosch, K., Grotegerd, D., Dohm, K., . . . Nenadić, I. (2020). S13. IMPACT OF POLYGENIC AND POLY-ENVIRONMENTAL RISK FACTORS ON A PSYCHOSIS RISK PHENOTYPE EXPLAINED THROUGH BRAIN STRUCTURE. Schizophrenia Bulletin, 46(Supplement_1), S35-S36. doi:10.1093/schbul/sbaa031.079
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.
Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. -K., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., . . . McIntosh, A. M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.. Nature communications, 11(1), 2301. doi:10.1038/s41467-020-16022-0
Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., . . . Sullivan, P. F. (2020). Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.. Nature genetics, 52(5), 482-493. doi:10.1038/s41588-020-0610-9
Minimal phenotyping yields genome-wide association signals of low specificity for major depression
Cai, N., Revez, J. A., Adams, M. J., Andlauer, T. F. M., Breen, G., Byrne, E. M., . . . Flint, J. (2020). Minimal phenotyping yields genome-wide association signals of low specificity for major depression. NATURE GENETICS, 52(4), 437-+. doi:10.1038/s41588-020-0594-5
“The Heidelberg Five” Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment
The genetic architecture of the human cerebral cortex
Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., . . . Medland, S. E. (2020). The genetic architecture of the human cerebral cortex. SCIENCE, 367(6484), 1340-+. doi:10.1126/science.aay6690
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., . . . Borglum, A. D. (2020). Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. BIOLOGICAL PSYCHIATRY, 87(5), 419-430. doi:10.1016/j.biopsych.2019.06.031
Polygenic risk scores outperform machine learning methods in predicting coronary artery disease status
Gola, D., Erdmann, J., Mueller-Myhsok, B., Schunkert, H., & Koenig, I. R. (2020). Polygenic risk scores outperform machine learning methods in predicting coronary artery disease status. GENETIC EPIDEMIOLOGY, 44(2), 125-138. doi:10.1002/gepi.22279
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
Arloth, J., Eraslan, G., Andlauer, T. F. M., Martins, J., Iurato, S., Kühnel, B., . . . Mueller, N. S. (2020). DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.. PLoS computational biology, 16(2), e1007616. doi:10.1371/journal.pcbi.1007616
Identification of Restless Legs Syndrome Genes by Mutational Load Analysis
Tilch, E., Schormair, B., Zhao, C., Salminen, A. V., Nikolic, A. A., Holzknecht, E., . . . Oexle, K. (2020). Identification of Restless Legs Syndrome Genes by Mutational Load Analysis. ANNALS OF NEUROLOGY, 87(2), 184-193. doi:10.1002/ana.25658
A different view on fine-scale population structure in Western African populations
Chaichoompu, K., Abegaz, F., Cavadas, B., Fernandes, V., Mueller-Myhsok, B., Pereira, L., & Van Steen, K. (2020). A different view on fine-scale population structure in Western African populations. HUMAN GENETICS, 139(1), 45-59. doi:10.1007/s00439-019-02069-7
Deep targeted-NGS identifies RLS genes by differential burden with low-frequency variants and differential target sequencing depth
Tilch, E., Schormair, B., Zhao, C., Salminen, A., Nikolic, A. A., Holzknecht, E., . . . Oexle, K. (2020). Deep targeted-NGS identifies RLS genes by differential burden with low-frequency variants and differential target sequencing depth. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 28 (pp. 415). Retrieved from https://www.webofscience.com/
Genome-Wide Association Study Identifies Novel Risk Loci in Patients with Transposition of the Great Arteries and Anomalies of the Thoracic Arteries and Veins
Lahm, H., Jia, M., Dreßen, M., Gilsbach, R., Hein, L., Lange, R., . . . Krane, M. (2020). Genome-Wide Association Study Identifies Novel Risk Loci in Patients with Transposition of the Great Arteries and Anomalies of the Thoracic Arteries and Veins. In The Thoracic and Cardiovascular Surgeon. Georg Thieme Verlag KG. doi:10.1055/s-0040-1705331
IMPACT OF POLYGENIC AND POLY-ENVIRONMENTAL RISK FACTORS ON A PSYCHOSIS RISK PHENOTYPE EXPLAINED THROUGH BRAIN STRUCTURE
Meller, T., Schmitt, S., Stein, F., Brosch, K., Grotegerd, D., Dohm, K., . . . Nenadic, I. (2020). IMPACT OF POLYGENIC AND POLY-ENVIRONMENTAL RISK FACTORS ON A PSYCHOSIS RISK PHENOTYPE EXPLAINED THROUGH BRAIN STRUCTURE. In SCHIZOPHRENIA BULLETIN Vol. 46 (pp. S35-S36). Retrieved from https://www.webofscience.com/
Influence of CRHR1 genotype on sleep and cortisol of healthy volunteers after Trier Social Stress Test in the late evening
Weeger, J., Ising, M., Mueller-Myhsok, B., Uhr, M., Schmidt, U., Yassouridis, A., & Steiger, A. (2020). Influence of CRHR1 genotype on sleep and cortisol of healthy volunteers after Trier Social Stress Test in the late evening. In JOURNAL OF SLEEP RESEARCH Vol. 29 (pp. 117-118). Retrieved from https://www.webofscience.com/
Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data
Passero, K., He, X., Zhou, J., Mueller-Myhsok, B., Kleber, M. E., Maerz, W., & Hall, M. A. (2020). Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data. PACIFIC SYMPOSIUM ON BIOCOMPUTING 2020, 659-670. Retrieved from https://www.webofscience.com/
2019
Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways
Foo, J. C., Trautmann, N., Sticht, C., Treutlein, J., Frank, J., Streit, F., . . . Rietschel, M. (2019). Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways. TRANSLATIONAL PSYCHIATRY, 9(1). doi:10.1038/s41398-019-0671-7
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
Gassen, N. C., Niemeyer, D., Muth, D., Corman, V. M., Martinelli, S., Gassen, A., . . . Rein, T. (2019). SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-13659-4
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, P. H., Anttila, V., Won, H., Feng, Y. -C. A., Rosenthal, J., Zhu, Z., . . . Smoller, J. W. (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. CELL, 179(7), 1469-+. doi:10.1016/j.cell.2019.11.020
Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Kogelman, L. J. A., Esserlind, A. -L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., . . . Consortium, I. H. G. (2019). Migraine polygenic risk score associates with efficacy of migraine-specific drugs. Neurology Genetics, 5(6). doi:10.1212/NXG.0000000000000364
Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data
Passero, K., He, X., Zhou, J., Mueller-Myhsok, B., Kleber, M. E., Maerz, W., & Hall, M. A. (2019). Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data. In Biocomputing 2020 (pp. 659-670). WORLD SCIENTIFIC. doi:10.1142/9789811215636_0058
Genetic architecture of subcortical brain structures in 38,851 individuals
Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., . . . Ikram, M. A. (2019). Genetic architecture of subcortical brain structures in 38,851 individuals. NATURE GENETICS, 51(11), 1624-+. doi:10.1038/s41588-019-0511-y
INVESTIGATING THE COMMON GENETIC BASIS OF ANTIDEPRESSANT RESPONSE
Pain, O., Hodgson, K., Trubetskoy, V., Baune, B., Biernacka, J., Fabbri, C., . . . Lewis, C. (2019). INVESTIGATING THE COMMON GENETIC BASIS OF ANTIDEPRESSANT RESPONSE. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 (pp. S91-S92). doi:10.1016/j.euroneuro.2019.07.198
LONGITUDINAL TRANSCRIPTOME-WIDE GENE EXPRESSION ANALYSIS OF SLEEP DEPRIVATION TREATMENT INDICATES INVOLVEMENT OF CIRCADIAN GENES AND IMMUNE PATHWAYS
Foo, J., Trautmann, N., Sticht, C., Treutlein, J., Frank, J., Streit, F., . . . Rietschel, M. (2019). LONGITUDINAL TRANSCRIPTOME-WIDE GENE EXPRESSION ANALYSIS OF SLEEP DEPRIVATION TREATMENT INDICATES INVOLVEMENT OF CIRCADIAN GENES AND IMMUNE PATHWAYS. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 (pp. S136). doi:10.1016/j.euroneuro.2019.08.045
Genetic factors influencing a neurobiological substrate for psychiatric disorders
Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton
Gampawar, P., Saba, Y., Werner, U., Schmidt, R., Mueller-Myhsok, B., & Schmidt, H. (2019). Evaluation of the Performance of AmpliSeq and SureSelect Exome Sequencing Libraries for Ion Proton. FRONTIERS IN GENETICS, 10. doi:10.3389/fgene.2019.00856
Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies
Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models
Paul, R., Andlauer, T. F. M., Czamara, D., Hoehn, D., Lucae, S., Puetz, B., . . . Saemann, P. G. (2019). Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models. TRANSLATIONAL PSYCHIATRY, 9. doi:10.1038/s41398-019-0524-4
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
Mullins, N., Bigdeli, T. B., Borglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., . . . Consortium, P. G. (2019). GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. American Journal of Psychiatry, 176(8), 651-660. doi:10.1176/appi.ajp.2019.18080957
Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis.
Gasperi, C., Salmen, A., Antony, G., Bayas, A., Heesen, C., Kümpfel, T., . . . German Competence Network of Multiple Sclerosis. (2019). Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis.. JAMA neurology, 76(7), 841-849. doi:10.1001/jamaneurol.2019.0905
CSF parameters associated with early MRI activity in patients with MS
Klein, A., Selter, R. C., Hapfelmeier, A., Berthele, A., Mueller-Myhsok, B., Pongratz, V., . . . Hemmer, B. (2019). CSF parameters associated with early MRI activity in patients with MS. NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 6(4). doi:10.1212/NXI.0000000000000573
Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa
Walton, E., Hibar, D., Yilmaz, Z., Jahanshad, N., Cheung, J., Batury, V. -L., . . . Bulik, C. M. (2019). Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa. MOLECULAR NEUROBIOLOGY, 56(7), 5146-5156. doi:10.1007/s12035-018-1439-4
Iron Metabolism, Hepcidin, and Mortality (the Ludwigshafen Risk and Cardiovascular Health Study)
Grammer, T. B., Scharnagl, H., Dressel, A., Kleber, M. E., Silbernagel, G., Pilz, S., . . . Strnad, P. (2019). Iron Metabolism, Hepcidin, and Mortality (the Ludwigshafen Risk and Cardiovascular Health Study). CLINICAL CHEMISTRY, 65(7), 849-861. doi:10.1373/clinchem.2018.297242
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hamalainen, E., . . . Sullivan, P. F. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-10461-0
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk
Zannas, A. S., Jia, M., Hafner, K., Baumert, J., Wiechmann, T., Pape, J. C., . . . Binder, E. B. (2019). Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(23), 11370-11379. doi:10.1073/pnas.1816847116
Associations of schizophrenia risk genes <i>ZNF804A</i> and <i>CACNA1C</i> with schizotypy and modulation of attention in healthy subjects
Meller, T., Schmitt, S., Stein, F., Brosch, K., Mosebach, J., Yueksel, D., . . . Nenadic, I. (2019). Associations of schizophrenia risk genes <i>ZNF804A</i> and <i>CACNA1C</i> with schizotypy and modulation of attention in healthy subjects. SCHIZOPHRENIA RESEARCH, 208, 67-75. doi:10.1016/j.schres.2019.04.018
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., . . . Stahl, E. A. (2019). Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.. Nature genetics, 51(6), 1068. doi:10.1038/s41588-019-0435-6
Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression
Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population
Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., . . . Consortium, P. G. (2019). Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population. JAMA PSYCHIATRY, 76(5), 516-525. doi:10.1001/jamapsychiatry.2018.4166
Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium
Polimanti, R., Peterson, R. E., Ong, J. -S., MacGregor, S., Edwards, A. C., Clarke, T. -K., . . . Neale, B. M. (2019). Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. PSYCHOLOGICAL MEDICINE, 49(7), 1218-1226. doi:10.1017/S0033291719000667
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., . . . Sklar, P. (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. NATURE GENETICS, 51(5), 793-+. doi:10.1038/s41588-019-0397-8
Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 and Intimate Partner Violence on Emotional and Cognitive Development in Childhood.
Halldorsdottir, T., Kurtoic, D., Müller-Myhsok, B., Binder, E. B., & Blair, C. (2019). Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 and Intimate Partner Violence on Emotional and Cognitive Development in Childhood.. The American journal of psychiatry, appiajp201918091018. doi:10.1176/appi.ajp.2019.18091018
Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults A 2-Sample Mendelian Randomization Study
Choi, K. W., Chen, C. -Y., Stein, M. B., Klimentidis, Y. C., Wang, M. -J., Koenen, K. C., . . . Sullivan, P. F. (2019). Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults A 2-Sample Mendelian Randomization Study. JAMA PSYCHIATRY, 76(4), 399-408. doi:10.1001/jamapsychiatry.2018.4175
Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity A Meta-analysis
Marini, S., Crawford, K., Morotti, A., Lee, M. J., Pezzini, A., Moomaw, C. J., . . . Sheth, K. (2019). Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity A Meta-analysis. JAMA NEUROLOGY, 76(4), 480-491. doi:10.1001/jamaneurol.2018.4519
Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials
Buck, D., Andlauer, T. F. M., Igl, W., Wicklein, E. -M., Muehlau, M., Weber, F., . . . Hemmer, B. (2019). Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. MULTIPLE SCLEROSIS JOURNAL, 25(4), 565-573. doi:10.1177/1352458518763089
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardinas, A. F., . . . Working, I. -G. S. (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. NATURE GENETICS, 51(4), 659-+. doi:10.1038/s41588-019-0364-4
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., . . . Morris, D. W. (2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 180(3), 223-231. doi:10.1002/ajmg.b.32716
Should phenotype of previous preterm birth influence management of women with short cervix in subsequent pregnancy? Comparison of vaginal progesterone and Arabin pessary
Care, A., Muller-Myhsok, B., Olearo, E., Todros, T., Caradeux, J., Goya, M., . . . Alfirevic, Z. (2019). Should phenotype of previous preterm birth influence management of women with short cervix in subsequent pregnancy? Comparison of vaginal progesterone and Arabin pessary. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 53(4), 529-534. doi:10.1002/uog.19118
Identification of common genetic risk variants for autism spectrum disorder
Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., . . . Wilson, C. H. (2019). Identification of common genetic risk variants for autism spectrum disorder. NATURE GENETICS, 51(3), 431-+. doi:10.1038/s41588-019-0344-8
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
Gialluisi, A., Andlauer, T. F. M., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., . . . Schulte-Koerne, G. (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. TRANSLATIONAL PSYCHIATRY, 9. doi:10.1038/s41398-019-0402-0
Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland
Arnau-Soler, A., Macdonald-Dunlop, E., Adams, M. J., Clarke, T. -K., MacIntyre, D. J., Milburn, K., . . . Sullivan, P. F. (2019). Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. TRANSLATIONAL PSYCHIATRY, 9. doi:10.1038/s41398-018-0360-y
<i>Cis</i>-epistasis at the <i>LPA</i> locus and risk of coronary artery disease
Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank
Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T. K., Gibson, J., . . . Nivard, M. G. (2019). Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(01), 91-100. doi:10.1016/j.bpsc.2018.07.006
BLOOD-BASED AUTISM SPECTRUM DISORDER SIGNATURES FROM THE ITALIAN AUTISM NETWORK COLLECTION
Filosi, M., Mueller-Myhsok, B., Muglia, P., & Domenici, E. (2019). BLOOD-BASED AUTISM SPECTRUM DISORDER SIGNATURES FROM THE ITALIAN AUTISM NETWORK COLLECTION. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 (pp. S912). doi:10.1016/j.euroneuro.2017.08.234
COMMON GENETIC VARIANTS ASSOCIATED WITH PERSONALITY DIMENSIONS IN THE HEIDELBERG COHORT STUDY OF THE ELDERLY (HeiDE): AN UPDATE
Heilbronner, U., Andlauer, T., Papiol, S., Budde, M., Strohmaier, J., Streit, F., . . . Schulze, T. G. (2019). COMMON GENETIC VARIANTS ASSOCIATED WITH PERSONALITY DIMENSIONS IN THE HEIDELBERG COHORT STUDY OF THE ELDERLY (HeiDE): AN UPDATE. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 (pp. S928). doi:10.1016/j.euroneuro.2017.08.263
Endophenotype Potential of Nucleus Accumbens Functional Connectivity: Effects of Polygenic Risk for Schizophrenia Interacting with Childhood Adversity
Endophenotype Potential of Nucleus Accumbens Functional Connectivity: Effects of Polygenic Risk for Schizophrenia Interacting with Childhood Adversity (2019). Journal of Psychiatry and Brain Science. doi:10.20900/jpbs.20190011
Establishing high sensitivity and specificity for exome sequencing on Ion Proton
Gampawar, P., Saba, Y., Werner, U., Schmidt, R., Mueller-Myhsok, B., & Schmidt, H. (2019). Establishing high sensitivity and specificity for exome sequencing on Ion Proton. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 27 (pp. 1636). Retrieved from https://www.webofscience.com/
Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy
Foo, J. C., Streit, F., Frank, J., Witt, S. H., Treutlein, J., Baune, B. T., . . . Worki, M. D. D. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 180(1), 35-45. doi:10.1002/ajmg.b.32700
Explaining RLS families using risk SNPs from GWAS
Tilch, E., Zhao, C., Salminen, A., Antic, A., Schormair, B., Oexle, K., . . . Winkelmann, J. (2019). Explaining RLS families using risk SNPs from GWAS. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 27 (pp. 658-659). Retrieved from https://www.webofscience.com/
GENETIC FACTORS INFLUENCING THE COMMON NEUROBIOLOGICAL SUBSTRATE FOR MENTAL DISORDERS
Andlauer, T., Muhleisen, T., Hoffstaedter, F., Teumer, A., Teuber, A., Reinbold, C., . . . Cichon, S. (2019). GENETIC FACTORS INFLUENCING THE COMMON NEUROBIOLOGICAL SUBSTRATE FOR MENTAL DISORDERS. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 29 (pp. S798). doi:10.1016/j.euroneuro.2017.08.032
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.
Drange, O. K., Smeland, O. B., Shadrin, A. A., Finseth, P. I., Witoelar, A., Frei, O., . . . Andreassen, O. A. (2019). Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.. Frontiers in neuroscience, 13, 220. doi:10.3389/fnins.2019.00220
Identification of functionally relevant genetic variants associated with multiple sclerosis using deep learning
Arloth, J., Eraslan, G., Andlauer, T., Gieger, C., Gold, R., Heilmann-Heimbach, S., . . . Mueller, N. (2019). Identification of functionally relevant genetic variants associated with multiple sclerosis using deep learning. In MULTIPLE SCLEROSIS JOURNAL Vol. 25 (pp. 906-907). Retrieved from https://www.webofscience.com/
Influence of ultraviolet radiation and diminished-function melanocortin 1 receptor variants on multiple sclerosis disease severity in two large multicenter cohort studies
Ostkamp, P., Goerlich, D., Andlauer, T. F. M., Salmen, A., Schulte-Mecklenbeck, A., Pignolet, B., . . . Schwab, N. (2019). Influence of ultraviolet radiation and diminished-function melanocortin 1 receptor variants on multiple sclerosis disease severity in two large multicenter cohort studies. In MULTIPLE SCLEROSIS JOURNAL Vol. 25 (pp. 59-60). Retrieved from https://www.webofscience.com/
Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 Intimate Partner Violence on Emotional and Cognitive Development in Childhood
Halldorsdottir, T., Kurtoic, D., Mueller-Myhsok, B., Binder, E., & Blair, C. (2019). Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 Intimate Partner Violence on Emotional and Cognitive Development in Childhood. In JOURNAL OF NEURAL TRANSMISSION Vol. 126 (pp. 1569-1570). Retrieved from https://www.webofscience.com/
2018
Epigenetic derepression of FKBP5 by aging and stress contributes to NF-ĸB-driven inflammation and cardiovascular risk
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
de Jong, S., Abdalla Diniz, M. J., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., . . . Shi, J. (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. COMMUNICATIONS BIOLOGY, 1. doi:10.1038/s42003-018-0155-y
Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
Pulit, S. L., Weng, L. -C., McArdle, P. F., Trinquart, L., Choi, S. H., Mitchell, B. D., . . . Sheth, K. (2018). Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes. NEUROLOGY-GENETICS, 4(6). doi:10.1212/NXG.0000000000000293
Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.
Arnau-Soler, A., Adams, M. J., Generation Scotland., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., Hayward, C., & Thomson, P. A. (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.. PloS one, 13(12), e0209160. doi:10.1371/journal.pone.0209160
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., . . . Team, A. R. (2018). Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21(12), 1656-1669. doi:10.1038/s41593-018-0275-1
Genetic variation in the Major Histocompatibility Complex and association with depression
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Minimal phenotyping yields GWAS hits of reduced specificity for major depression
Neurobiology of the major psychoses: a translational perspective on brain structure and function-the FOR2107 consortium.
Kircher, T., Wöhr, M., Nenadic, I., Schwarting, R., Schratt, G., Alferink, J., . . . Dannlowski, U. (2018). Neurobiology of the major psychoses: a translational perspective on brain structure and function-the FOR2107 consortium.. European archives of psychiatry and clinical neuroscience. doi:10.1007/s00406-018-0943-x
Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores
Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium
The genetic architecture of the human cerebral cortex
Planar cell polarity pathway and development of the human visual cortex
Molecular genetic overlap between migraine and major depressive disorder.
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., . . . Nyholt, D. R. (2018). Molecular genetic overlap between migraine and major depressive disorder.. European journal of human genetics : EJHG, 26(8), 1202-1216. doi:10.1038/s41431-018-0150-2
Shared genetic etiology between alcohol dependence and major depressive disorder
Foo, J. C., Streit, F., Treutlein, J., Ripke, S., Witt, S. H., Strohmaier, J., . . . Frank, J. (2018). Shared genetic etiology between alcohol dependence and major depressive disorder. PSYCHIATRIC GENETICS, 28(4), 66-70. doi:10.1097/YPG.0000000000000201
Sleep disturbance by pramipexole is modified by Meis1 in mice.
Salminen, A. V., Schormair, B., Flachskamm, C., Torres, M., Mueller-Myhsok, B., Kimura, M., & Winkelmann, J. (2018). Sleep disturbance by pramipexole is modified by Meis1 in mice. JOURNAL OF SLEEP RESEARCH, 27(4). doi:10.1111/jsr.12557
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.
Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., . . . Penninx, B. W. J. H. (2018). Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.. Biological psychiatry, 84(2), 138-147. doi:10.1016/j.biopsych.2017.09.009
Age at first birth in women is genetically associated with increased risk of schizophrenia.
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., & Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia.. Scientific reports, 8(1), 10168. doi:10.1038/s41598-018-28160-z
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework.
LeBlanc, M., Zuber, V., Thompson, W. K., Andreassen, O. A., Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium., Frigessi, A., & Andreassen, B. K. (2018). A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework.. BMC genomics, 19(1), 494. doi:10.1186/s12864-018-4859-7
Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., . . . Neale, B. M. (2018). Analysis of shared heritability in common disorders of the brain. SCIENCE, 360(6395), 1313-+. doi:10.1126/science.aap8757
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., . . . Case-Control, W. T. (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. CELL, 173(7), 1705-1715. doi:10.1016/j.cell.2018.05.046
From Epigenetic Associations to Biological and Psychosocial Explanations in Mental Health
Renzi, C., Provencal, N., Bassil, K. C., Evers, K., Kihlbom, U., Radford, E. J., . . . Rutten, B. P. F. (2018). From Epigenetic Associations to Biological and Psychosocial Explanations in Mental Health. NEUROEPIGENETICS AND MENTAL ILLNESS, 158, 299-323. doi:10.1016/bs.pmbts.2018.04.011
Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.
Ni, G., Moser, G., Schizophrenia Working Group of the Psychiatric Genomics Consortium., Wray, N. R., & Lee, S. H. (2018). Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.. American journal of human genetics, 102(6), 1185-1194. doi:10.1016/j.ajhg.2018.03.021
Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
Gormley, P., Kurki, M. I., Hiekkala, M. E., Veerapen, K., Häppölä, P., Mitchell, A. A., . . . Zwart, J. -A. (2018). Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families. Neuron, 98(4), 743-753.e4. doi:10.1016/j.neuron.2018.04.014
Genome Wide Association Scan identifies new variants associated with a cognitive predictor of dyslexia
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., . . . Working, M. D. D. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. NATURE GENETICS, 50(05), 668-681. doi:10.1038/s41588-018-0090-3
Statistical Genetics
Andlauer, T. F. M., Müller-Myhsok, B., & Ripke, S. (2018). Statistical Genetics. In Psychiatric Genetics (pp. 57-69). Oxford University Press. doi:10.1093/med/9780190221973.003.0004
Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
The P2RX7 polymorphism rs2230912 is associated with depression: A meta-analysis
Czamara, D., Mueller-Myhsok, B., & Lucae, S. (2018). The P2RX7 polymorphism rs2230912 is associated with depression: A meta-analysis. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 82, 272-277. doi:10.1016/j.pnpbp.2017.11.003
Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder
Muehleisen, T. W., Reinbold, C. S., Forstner, A. J., Abramova, L. I., Alda, M., Babadjanova, G., . . . Cichon, S. (2018). Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 228, 20-25. doi:10.1016/j.jad.2017.11.068
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.
Chang, H., Hoshina, N., Zhang, C., Ma, Y., Cao, H., Wang, Y., . . . Li, M. (2018). The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. MOLECULAR PSYCHIATRY, 23(2), 400-412. doi:10.1038/mp.2016.231
GWAS Analysis Reveals Previously Unknown Genomic Variants Associated with Different Subgroups of Congenital Heart Disease
Lahm, H., Jia, M., Dreßen, M., Puluca, N., Beck, N., Cleuziou, J., . . . Krane, M. (2018). GWAS Analysis Reveals Previously Unknown Genomic Variants Associated with Different Subgroups of Congenital Heart Disease. The Thoracic and Cardiovascular Surgeon, 66(S 01), S1-S110. doi:10.1055/s-0038-1628044
Genetic factors influencing the development of binding and neutralizing antibodies against interferon beta treatment in multiple sclerosis patients
Andlauer, T. F. M., Link, J., Buck, D., Ryner, M., Grummel, V., Auer, M., . . . Hemmer, B. (2018). Genetic factors influencing the development of binding and neutralizing antibodies against interferon beta treatment in multiple sclerosis patients. In MULTIPLE SCLEROSIS JOURNAL Vol. 24 (pp. 507-508). Retrieved from https://www.webofscience.com/
How well can we classify coronary artery disease using all genetic data and choosing the best classification algorithm?
Gola, D., Andlauer, T., Mirza-Schreiber, N., Zeng, L., Mueller-Myhsok, B., & Koenig, I. R. (2018). How well can we classify coronary artery disease using all genetic data and choosing the best classification algorithm?. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 701-702). Retrieved from https://www.webofscience.com/
2017
Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes
DNA Methylation signatures in panic disorder
Iurato, S., Carrillo-Roa, T., Arloth, J., Czamara, D., Diener-Hoelzl, L., Lange, J., . . . Erhardt, A. (2017). DNA Methylation signatures in panic disorder. TRANSLATIONAL PSYCHIATRY, 7. doi:10.1038/s41398-017-0026-1
Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders
Xiao, X., Wang, L., Wang, C., Yuan, T. -F., Zhou, D., Zheng, F., . . . Li, M. (2017). Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders. TRANSLATIONAL PSYCHIATRY, 7. doi:10.1038/s41398-017-0019-0
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.
Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., . . . CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. (2017). Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.. JAMA psychiatry, 74(12), 1214-1225. doi:10.1001/jamapsychiatry.2017.3016
Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus
Schulz, H., Ruppert, A. -K., Herms, S., Wolf, C., Mirza-Schreiber, N., Stegle, O., . . . Cichon, S. (2017). Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus. NATURE COMMUNICATIONS, 8. doi:10.1038/s41467-017-01818-4
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes.
Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., . . . Rietschel, M. (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes.. Scientific reports, 7(1), 15351. doi:10.1038/s41598-017-11852-3
Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
Schormair, B., Zhao, C., Bell, S., Tilch, E., Salminen, A. V., Putz, B., . . . Wilson, C. H. (2017). Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis. Lancet Neurol, 16(11), 898-907. doi:10.1016/S1474-4422(17)30327-7
Genetic Risk: Computation
Grimm, T., Müller‐Myhsok, B., & Zerres, K. (n.d.). Genetic Risk: Computation. In Unknown Book (pp. 1-7). Wiley. doi:10.1002/9780470015902.a0005433.pub2
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Direk, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., . . . Sullivan, P. F. (2017). An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. BIOLOGICAL PSYCHIATRY, 82(5), 322-329. doi:10.1016/j.biopsych.2016.11.013
Commentary: The importance of exploring dose-dependent, subtype-specific, and age-related effects of maltreatment on the HPA axis and the mediating link to psychopathology. A response to Fisher (2017)
White, L. O., Ising, M., von Klitzing, K., Sierau, S., Michel, A., Klein, A. M., . . . Stalder, T. (2017). Commentary: The importance of exploring dose-dependent, subtype-specific, and age-related effects of maltreatment on the HPA axis and the mediating link to psychopathology. A response to Fisher (2017). JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 58(9), 1011-1013. doi:10.1111/jcpp.12770
Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder.
Zeng, Y., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., . . . McIntosh, A. M. (2017). Genome-wide Regional Heritability Mapping Identifies a Locus Within the <i>TOX2</i> Gene Associated With Major Depressive Disorder. BIOLOGICAL PSYCHIATRY, 82(5), 312-321. doi:10.1016/j.biopsych.2016.12.012
Identification of a Bipolar Disorder Vulnerable Gene <i>CHDH</i> at 3p21.1
Chang, H., Li, L., Peng, T., Grigoroiu-Serbanescu, M., Bergen, S. E., Landen, M., . . . Li, M. (2017). Identification of a Bipolar Disorder Vulnerable Gene <i>CHDH</i> at 3p21.1. MOLECULAR NEUROBIOLOGY, 54(7), 5166-5176. doi:10.1007/s12035-016-0041-x
Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence.
White, L. O., Ising, M., von Klitzing, K., Sierau, S., Michel, A., Klein, A. M., . . . Stalder, T. (2017). Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 58(9), 998-1007. doi:10.1111/jcpp.12700
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants.
Winsvold, B. S., Bettella, F., Witoelar, A., Anttila, V., Gormley, P., Kurth, T., . . . International Headache Genetics Consortium. (2017). Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants.. PloS one, 12(9), e0185663. doi:10.1371/journal.pone.0185663
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Kim-Hellmuth, S., Bechheim, M., Puetz, B., Mohammadi, P., Nedelec, Y., Giangreco, N., . . . Hornung, V. (2017). Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. NATURE COMMUNICATIONS, 8. doi:10.1038/s41467-017-00366-1
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder
Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals.
Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., . . . McGuffin, P. (2017). Interaction between the <i>FTO</i> gene, body mass index and depression: meta-analysis of 13701 individualst. BRITISH JOURNAL OF PSYCHIATRY, 211(2), 70-76. doi:10.1192/bjp.bp.116.183475
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder
Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.
Treutlein, J., Frank, J., Streit, F., Reinbold, C. S., Juraeva, D., Degenhardt, F., . . . Rietschel, M. (2017). Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. GENES, 8(7). doi:10.3390/genes8070183
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., . . . Rietschel, M. (2017). Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. TRANSLATIONAL PSYCHIATRY, 7. doi:10.1038/tp.2017.115
Genetic effects influencing risk for major depressive disorder in China and Europe
Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. -A., Abdellaoui, A., . . . Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. TRANSLATIONAL PSYCHIATRY, 7. doi:10.1038/tp.2016.292
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
McLaughlin, R. L., Schijven, D., van Rheenen, W., van Eijk, K. R., O'Brien, M., Kahn, R. S., . . . Veldink, J. H. (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. NATURE COMMUNICATIONS, 8. doi:10.1038/ncomms14774
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Power, R. A., Tansey, K. E., Buttenschon, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., . . . Lewis, C. M. (2017). Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. BIOLOGICAL PSYCHIATRY, 81(4), 325-335. doi:10.1016/j.biopsych.2016.05.010
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia
Forstner, A. J., Hecker, J., Hofmann, A., Maaser, A., Reinbold, C. S., Muehleisen, T. W., . . . Noethen, M. M. (2017). Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLOS ONE, 12(2). doi:10.1371/journal.pone.0171595
Novel genetic loci associated with hippocampal volume
Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., . . . Ikram, M. A. (2017). Novel genetic loci associated with hippocampal volume. NATURE COMMUNICATIONS, 8. doi:10.1038/ncomms13624
Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk
Zannas, A., Jia, M., Baumert, J., Hafner, K., Koedel, M., Haehle, A., . . . Binder, E. (2017). Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk. In NEUROPSYCHOPHARMACOLOGY Vol. 42 (pp. S310-S311). Retrieved from https://www.webofscience.com/
COMMON GENETIC VARIANTS ASSOCIATED WITH PERSONALITY DIMENSIONS IN THE HEIDELBERG COHORT STUDY OF THE ELDERLY (HEIDE)
Heilbronner, U., Andlauer, T. F. M., Papiol, S., Budde, M., Strohmaier, J., Streit, F., . . . Schulze, T. G. (2017). COMMON GENETIC VARIANTS ASSOCIATED WITH PERSONALITY DIMENSIONS IN THE HEIDELBERG COHORT STUDY OF THE ELDERLY (HEIDE). In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S381-S382). doi:10.1016/j.euroneuro.2016.09.413
Classification of CAD Status Using Machine Learning Approaches
Gola, D., Andlauer, T., Mirza-Schreiber, N., Zeng, L., Delgado, G., Kleber, M., . . . Koneig, I. R. (2017). Classification of CAD Status Using Machine Learning Approaches. In HUMAN HEREDITY Vol. 83 (pp. 9). Retrieved from https://www.webofscience.com/
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, C. R., Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., . . . Endophenotypes, P. (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. NATURE GENETICS, 49(1), 27-35. doi:10.1038/ng.3725
IDENTIFICATION OF GENETIC INTERACTIONS INVOLVED IN DYSLEXIA PATHOGENESIS
Karbalai, N., Czamara, D., Moll, K., Ramus, F., Malik, R., Scerri, T. S., . . . Muller-Myhsok, B. (2017). IDENTIFICATION OF GENETIC INTERACTIONS INVOLVED IN DYSLEXIA PATHOGENESIS. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S183-S184). Retrieved from https://www.webofscience.com/
POLYGENIC RISK FOR BIP, MDD, AND SCZ IN ANDALUSIAN MULTIPLEX FAMILIES
Andlauer, T., Parra, J. G., Strohmaier, J., Streit, F., Frank, J., Forstner, A. J., . . . Rietschel, M. (2017). POLYGENIC RISK FOR BIP, MDD, AND SCZ IN ANDALUSIAN MULTIPLEX FAMILIES. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S385-S386). doi:10.1016/j.euroneuro.2016.09.419
POLYGENIC SCORES DERIVED FROM NEUROIMAGING ENDOPHENOTYPES PREDICT OUTCOMES TO PSYCHOTHERAPY AND MEDICATION TREATMENTS FOR MAJOR DEPRESSIVE DISORDER
Carrillo-Roa, T., Boadie, D., McGrath, C., Mueller-Myhsok, B., Craighed, E., Mayberg, H., & Binder, E. (2017). POLYGENIC SCORES DERIVED FROM NEUROIMAGING ENDOPHENOTYPES PREDICT OUTCOMES TO PSYCHOTHERAPY AND MEDICATION TREATMENTS FOR MAJOR DEPRESSIVE DISORDER. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S486). doi:10.1016/j.euroneuro.2016.09.576
SEX-SPECIFIC DNA METHYLATION SIGNATURES IN PANIC DISORDER
Iurato, S., Carrillo-Roa, T., Arloth, J., Czamara, D., Ising, M., Lucae, S., . . . Erhardt, A. (2017). SEX-SPECIFIC DNA METHYLATION SIGNATURES IN PANIC DISORDER. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S446-S447). doi:10.1016/j.euroneuro.2016.09.512
USING POLYGENIC SCORES BASED ON SCHNEIDERIAN FIRST RANK SYMPTOMS TO CHARACTERIZE DISEASE TRAJECTORIES IN SEVERE MENTAL ILLNESSES
Anderson-Schmidt, H., Papiol, S., Andlauer, T. F. M., Heilbronner, U., Budde, M., Kalman, J., . . . Schulze, T. G. (2017). USING POLYGENIC SCORES BASED ON SCHNEIDERIAN FIRST RANK SYMPTOMS TO CHARACTERIZE DISEASE TRAJECTORIES IN SEVERE MENTAL ILLNESSES. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S395-S396). doi:10.1016/j.euroneuro.2016.09.433
2016
Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis
Li, M., Huang, L., Grigoroiu-Serbanescu, M., Bergen, S. E., Landen, M., Hultman, C. M., . . . Rietschel, M. (2016). Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. MOLECULAR NEUROBIOLOGY, 53(10), 6608-6619. doi:10.1007/s12035-015-9559-6
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Renteria, M. E., . . . SYS. (2016). Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience, 19(12), 1569-1582. doi:10.1038/nn.4398
Genetic variants in <i>RBFOX3</i> are associated with sleep latency
Amin, N., Allebrandt, K. V., van der Spek, A., Mueller-Myhsok, B., Hek, K., Teder-Laving, M., . . . van Duijn, C. M. (2016). Genetic variants in <i>RBFOX3</i> are associated with sleep latency. EUROPEAN JOURNAL OF HUMAN GENETICS, 24(10), 1488-1495. doi:10.1038/ejhg.2016.31
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A., . . . Keller, M. C. (2016). No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLOS GENETICS, 12(10). doi:10.1371/journal.pgen.1006343
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., . . . Palotie, A. (2016). Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.. Nature genetics, 48(10), 1296. doi:10.1038/ng1016-1296c
Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.
Khankari, N. K., Shu, X. -O., Wen, W., Kraft, P., Lindström, S., Peters, U., . . . Transdisciplinary Research in Cancer of the Lung (TRICL). (2016). Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.. PLoS medicine, 13(9), e1002118. doi:10.1371/journal.pmed.1002118
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
Fehringer, G., Kraft, P., Pharoah, P. D., Eeles, R. A., Chatterjee, N., Schumacher, F. R., . . . Hung, R. J. (2016). Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. CANCER RESEARCH, 76(17), 5103-5114. doi:10.1158/0008-5472.CAN-15-2980
Hair cortisol in maltreated children and adolescents: Importance of developmental period and maltreatment characteristics
Stalder, T., Ising, M., von Klitzing, K., Sierau, S., Michel, A., Klein, A., . . . White, L. O. (2016). Hair cortisol in maltreated children and adolescents: Importance of developmental period and maltreatment characteristics. PSYCHONEUROENDOCRINOLOGY, 71, 73. doi:10.1016/j.psyneuen.2016.07.190
Influence of 25(OH)D levels and genetic variants on disease severity in MS.
Andlauer, T. F. M., Koechert, K., Muehlau, M., Munger, K. L., Fitzgerald, K. C., Arnason, B. G. W., . . . Mueller-Myhsok, B. (2016). Influence of 25(OH)D levels and genetic variants on disease severity in MS.. In MULTIPLE SCLEROSIS JOURNAL Vol. 22 (pp. 842-843). Retrieved from https://www.webofscience.com/
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., . . . Milani, L. (2016). Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics, 48(8), 856-866. doi:10.1038/ng.3598
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Andlauer, T. F. M., Buck, D., Antony, G., Bayas, A., Bechmann, L., Berthele, A., . . . Müller-Myhsok, B. (2016). Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.. Science advances, 2(6), 0. doi:10.1126/sciadv.1501678
Gene-based pleiotropy across migraine with aura and migraine without aura patient groups.
Zhao, H., Eising, E., de Vries, B., Vijfhuizen, L. S., Anttila, V., Winsvold, B. S., . . . Nyholt, D. R. (2016). Gene-based pleiotropy across migraine with aura and migraine without aura patient groups. CEPHALALGIA, 36(7), 648-657. doi:10.1177/0333102415591497
Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.
Gao, C., Patel, C. J., Michailidou, K., Peters, U., Gong, J., Schildkraut, J., . . . the Colorectal Transdisciplinary Study (CORECT); Discovery, Biology and Risk of Inherited Variants in Breast Cancer (DRIVE); Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE); Follow-up of Ovarian Cancer Genetic Association and Interaction Studies (FOCI); and Transdisciplinary Research in Cancer of the Lung (TRICL). (2016). Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.. International journal of epidemiology, 45(3), 896-908. doi:10.1093/ije/dyw129
Association of the <i>OPRM1</i> Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative <i>de novo</i> Meta-Analysis of European-Ancestry Cohorts
Schwantes-An, T. -H., Zhang, J., Chen, L. -S., Hartz, S. M., Culverhouse, R. C., Chen, X., . . . Saccone, N. L. (2016). Association of the <i>OPRM1</i> Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative <i>de novo</i> Meta-Analysis of European-Ancestry Cohorts. BEHAVIOR GENETICS, 46(2), 151-169. doi:10.1007/s10519-015-9737-3
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., . . . Sullivan, P. F. (2016). Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience, 19(3), 420-431. doi:10.1038/nn.4228
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.
Bigdeli, T. B., Ripke, S., Bacanu, S. -A., Lee, S. H., Wray, N. R., Gejman, P. V., . . . Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2016). Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 171B(2), 276-289. doi:10.1002/ajmg.b.32402
A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium
Schizophrenia risk from complex variation of complement component 4
Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., . . . McCarroll, S. A. (2016). Schizophrenia risk from complex variation of complement component 4. Nature, 530(7589), 177-183. doi:10.1038/nature16549
Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.
Traylor, M., Zhang, C. R., Adib-Samii, P., Devan, W. J., Parsons, O. E., Lanfranconi, S., . . . International Stroke Genetics Consortium. (2016). Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.. Neurology, 86(2), 146-153. doi:10.1212/wnl.0000000000002263
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine (vol 48, pg 856, 2016)
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., . . . Palotie, A. (2016). Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine (vol 48, pg 856, 2016). NATURE GENETICS, 48(10), 1296. doi:10.1038/ng1016-1296c
Polygenic Scores Derived from Neuroimaging Endophenotypes Predict Outcomes to Psychotherapy and Medication Treatments for Major Depressive Disorder
Carrillo-Roa, T., Dunlop, B. W., McGrath, C. L., Czamara, D., Zannas, A. S., Kelley, M. E., . . . Binder, E. B. (2016). Polygenic Scores Derived from Neuroimaging Endophenotypes Predict Outcomes to Psychotherapy and Medication Treatments for Major Depressive Disorder. In BIOLOGICAL PSYCHIATRY Vol. 79 (pp. 155S-156S). Retrieved from https://www.webofscience.com/
2015
Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array
Dankowski, T., Buck, D., Andlauer, T. F. M., Antony, G., Bayas, A., Bechmann, L., . . . Ziegler, A. (2015). Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array. GENETIC EPIDEMIOLOGY, 39(8), 601-608. doi:10.1002/gepi.21933
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder
Forstner, A. J., Hofmann, A., Maaser, A., Sumer, S., Khudayberdiev, S., Muehleisen, T. W., . . . Noethen, M. M. (2015). Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. TRANSLATIONAL PSYCHIATRY, 5. doi:10.1038/tp.2015.159
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Supportive evidence for <i>FOXP1</i>, <i>BARX1</i>, and <i>FOXF1</i> as genetic risk loci for the development of esophageal adenocarcinoma
Becker, J., May, A., Gerges, C., Anders, M., Veits, L., Weise, K., . . . Schumacher, J. (2015). Supportive evidence for <i>FOXP1</i>, <i>BARX1</i>, and <i>FOXF1</i> as genetic risk loci for the development of esophageal adenocarcinoma. CANCER MEDICINE, 4(11), 1700-1704. doi:10.1002/cam4.500
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., . . . Price, A. L. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.. American journal of human genetics, 97(4), 576-592. doi:10.1016/j.ajhg.2015.09.001
Familiality and SNP heritability of age at onset and episodicity in major depressive disorder
Ferentinos, P., Koukounari, A., Power, R., Rivera, M., Uher, R., Craddock, N., . . . Lewis, C. M. (2015). Familiality and SNP heritability of age at onset and episodicity in major depressive disorder. PSYCHOLOGICAL MEDICINE, 45(10), 2215-2225. doi:10.1017/S0033291715000215
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., . . . Social Science Genetic Association Consortium Corporate Collaborator. (2015). The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.. Molecular psychiatry, 20(6), 735-743. doi:10.1038/mp.2015.50
Analyzing pathways from childhood maltreatment to internalizing symptoms and disorders in children and adolescents (AMIS): a study protocol
White, L. O., Klein, A. M., Kirschbaum, C., Kurz-Adam, M., Uhr, M., Mueller-Myhsok, B., . . . von Klitzing, K. (2015). Analyzing pathways from childhood maltreatment to internalizing symptoms and disorders in children and adolescents (AMIS): a study protocol. BMC PSYCHIATRY, 15. doi:10.1186/s12888-015-0512-z
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders
Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K. V., . . . PGC, P. G. C. (2015). Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. NEURON, 86(05), 1189-1202. doi:10.1016/j.neuron.2015.05.034
<i>ABCB1</i> gene variants and antidepressant treatment outcome: A meta-analysis
Breitenstein, B., Brueckl, T. M., Ising, M., Mueller-Myhsok, B., Holsboer, F., & Czamara, D. (2015). <i>ABCB1</i> gene variants and antidepressant treatment outcome: A meta-analysis. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 168(4), 274-283. doi:10.1002/ajmg.b.32309
Genetic analysis for a shared biological basis between migraine and coronary artery disease.
Winsvold, B. S., Nelson, C. P., Malik, R., Gormley, P., Anttila, V., Vander Heiden, J., . . . CARDIoGRAM Consortium and the International Headache Genetics Consortium. (2015). Genetic analysis for a shared biological basis between migraine and coronary artery disease.. Neurology. Genetics, 1(1), e10. doi:10.1212/nxg.0000000000000010
Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice
Brenndoerfer, J., Altmann, A., Widner-Andrae, R., Puetz, B., Czamara, D., Tilch, E., . . . Czibere, L. (2015). Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice. PLOS ONE, 10(5). doi:10.1371/journal.pone.0128465
Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.
Malik, R., Freilinger, T., Winsvold, B. S., Anttila, V., Vander Heiden, J., Traylor, M., . . . METASTROKE Collaboration of the International Stroke Genetics Consortium. (2015). Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.. Neurology, 84(21), 2132-2145. doi:10.1212/wnl.0000000000001606
Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies
Nyholt, D. R., Anttila, V., Winsvold, B. S., Kurth, T., Stefansson, H., Kallela, M., . . . Palotie, A. (2015). Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies. CEPHALALGIA, 35(6), 489-499. doi:10.1177/0333102414547784
Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients
Zaba, M., Kirmeier, T., Ionescu, I. A., Wollweber, B., Buell, D. R., Gall-Kleebach, D. J., . . . Schmidt, U. (2015). Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients. PSYCHONEUROENDOCRINOLOGY, 55, 102-115. doi:10.1016/j.psyneuen.2015.02.005
A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder
Hung, C. -F., Breen, G., Czamara, D., Corre, T., Wolf, C., Kloiber, S., . . . Rivera, M. (2015). A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder. BMC MEDICINE, 13. doi:10.1186/s12916-015-0334-3
Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
Debette, S., Verbaas, C. A. I., Bressler, J., Schuur, M., Smith, A., Bis, J. C., . . . Mosley, T. H. J. (2015). Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. BIOLOGICAL PSYCHIATRY, 77(8), 749-763. doi:10.1016/j.biopsych.2014.08.027
Common genetic variants influence human subcortical brain structures
Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivieres, S., Jahanshad, N., . . . SYS. (2015). Common genetic variants influence human subcortical brain structures. NATURE, 520(7546), 224-229. doi:10.1038/nature14101
594 Discriminating metastasized from non-metastasized seminoma using small RNA-expression in tumour tissue and peripheral blood
Ruf, C. G. A., Port, M., Matthies, C., Meineke, V., Müller-Myhsok, B., Wagner, W., . . . Abend, M. (2015). 594 Discriminating metastasized from non-metastasized seminoma using small RNA-expression in tumour tissue and peripheral blood. European Urology Supplements, 14(2), e594-e594a. doi:10.1016/s1569-9056(15)60587-5
Association of a Brain Methylation Site With Clinical Outcomes in Depression Does Not Replicate Across Populations
Uher, R., Ripke, S., Mueller-Myhsok, B., Lewis, C. M., & Perlis, R. H. (2015). Association of a Brain Methylation Site With Clinical Outcomes in Depression Does Not Replicate Across Populations. AMERICAN JOURNAL OF PSYCHIATRY, 172(4), 395-396. doi:10.1176/appi.ajp.2015.14101348
Genetic Relationship Between Depression and Body Mass Index
Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., . . . McGuffin, P. (2015). Genetic Relationship Between Depression and Body Mass Index. In EUROPEAN PSYCHIATRY Vol. 30. doi:10.1016/S0924-9338(15)30560-5
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Bulik-Sullivan, B. K., Loh, P. -R., Finucane, H. K., Ripke, S., Yang, J., Schizophrenia Working Group of the Psychiatric Genomics Consortium., . . . Neale, B. M. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.. Nature genetics, 47(3), 291-295. doi:10.1038/ng.3211
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
O'Dushlaine, C., Rossin, L., Lee, P. H., Duncan, L., Parikshak, N. N., Newhouse, S., . . . Breen, G. (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. NATURE NEUROSCIENCE, 18(2), 199-209. doi:10.1038/nn.3922
MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene
Nischwitz, S., Wolf, C., Andlauer, T. F. M., Czamara, D., Zettl, U. K., Rieckmann, P., . . . Weber, F. (2015). MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene. JOURNAL OF NEUROIMMUNOLOGY, 279, 46-49. doi:10.1016/j.jneuroim.2015.01.008
Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder.
Maier, R., Moser, G., Chen, G. -B., Ripke, S., Cross-Disorder Working Group of the Psychiatric Genomics Consortium., Coryell, W., . . . Lee, S. H. (2015). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder.. American journal of human genetics, 96(2), 283-294. doi:10.1016/j.ajhg.2014.12.006
Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder.
Jacobsen, K. K., Nievergelt, C. M., Zayats, T., Greenwood, T. A., Anttila, V., Akiskal, H. S., . . . Oedegaard, K. J. (2015). Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder.. Journal of affective disorders, 172, 453-461. doi:10.1016/j.jad.2014.10.004
<i>XRCC5</i> as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set-Based Analysis and Follow-up Studies in Drosophila and Humans
Juraeva, D., Treutlein, J., Scholz, H., Frank, J., Degenhardt, F., Cichon, S., . . . Rietschel, M. (2015). <i>XRCC5</i> as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set-Based Analysis and Follow-up Studies in Drosophila and Humans. NEUROPSYCHOPHARMACOLOGY, 40(2), 361-371. doi:10.1038/npp.2014.178
Exome Array GWAS in 10,000 Germans Identifies Association between MUC22 and Multiple Sclerosis
Dankowski, T., Buck, D., Andlauer, T. F., Antony, G., Bayas, A., Bechmann, L., . . . Ziegler, A. (2015). Exome Array GWAS in 10,000 Germans Identifies Association between MUC22 and Multiple Sclerosis. In HUMAN HEREDITY Vol. 79 (pp. 32-33). Retrieved from https://www.webofscience.com/
Exome array GWAS in 10,000 Germans identifies association between MUC22 and multiple sclerosis
Buck, D., Dankowski, T., Bayas, A., Gold, R., Heesen, C., Hohlfeld, R., . . . Hemmer, B. (2015). Exome array GWAS in 10,000 Germans identifies association between MUC22 and multiple sclerosis. In EUROPEAN JOURNAL OF NEUROLOGY Vol. 22 (pp. 29). Retrieved from https://www.webofscience.com/
Genome-wide association analysis in a German multiple sclerosis cohort
Andlauer, T. F. M., Buck, D., Hemmer, B., & Mueller-Myhsok, B. (2015). Genome-wide association analysis in a German multiple sclerosis cohort. In MULTIPLE SCLEROSIS JOURNAL Vol. 21 (pp. 144). Retrieved from https://www.webofscience.com/
Identification and characterization of novel associations in the <i>CASP8</i>/<i>ALS2CR12</i> region on chromosome 2 with breast cancer risk
Lin, W. -Y., Camp, N. J., Ghoussaini, M., Beesley, J., Michailidou, K., Hopper, J. L., . . . Cox, A. (2015). Identification and characterization of novel associations in the <i>CASP8</i>/<i>ALS2CR12</i> region on chromosome 2 with breast cancer risk. HUMAN MOLECULAR GENETICS, 24(1), 285-298. doi:10.1093/hmg/ddu431
Polygenic Predictors of Antidepressant Treatment-Specific Response
Carrillo-Roa, T., McGrath, C. L., Zannas, A. S., Muller-Myhsok, B., Kelley, M. E., Craighead, W. E., . . . Binder, E. B. (2015). Polygenic Predictors of Antidepressant Treatment-Specific Response. In BIOLOGICAL PSYCHIATRY Vol. 77. Retrieved from https://www.webofscience.com/
2014
MicroRNA Related Polymorphisms and Breast Cancer Risk
Khan, S., Greco, D., Michailidou, K., Milne, R. L., Muranen, T. A., Heikkinen, T., . . . Nevanlinna, H. (2014). MicroRNA Related Polymorphisms and Breast Cancer Risk. PLOS ONE, 9(11). doi:10.1371/journal.pone.0109973
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., . . . SWE-SCZ Consortium. (2014). Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.. American journal of human genetics, 95(5), 535-552. doi:10.1016/j.ajhg.2014.10.004
Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes
Kim, S., Becker, J., Bechheim, M., Kaiser, V., Noursadeghi, M., Fricker, N., . . . Schumacher, J. (n.d.). Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes. Nature Communications, 5. doi:10.1038/ncomms6236
The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels
van Leeuwen, E. M., Smouter, F. A. S., Kam-Thong, T., Karbalai, N., Smith, A. V., Harris, T. B., . . . van Duijn, C. M. (2014). The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels. PLOS ONE, 9(10). doi:10.1371/journal.pone.0109290
Biological insights from 108 schizophrenia-associated genetic loci
Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. -H., Holmans, P. A., . . . Consor, W. T. C. -C. (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510), 421-427. doi:10.1038/nature13595
Targeted Resequencing and Systematic In Vivo Functional Testing Identifies Rare Variants in <i>MEIS1</i> as Significant Contributors to Restless Legs Syndrome
Schulte, E. C., Kousi, M., Tan, P. L., Tilch, E., Knauf, F., Lichtner, P., . . . Winkelmann, J. (2014). Targeted Resequencing and Systematic In Vivo Functional Testing Identifies Rare Variants in <i>MEIS1</i> as Significant Contributors to Restless Legs Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS, 95(1), 85-95. doi:10.1016/j.ajhg.2014.06.005
Blood <i>cis</i>-eQTL Analysis Fails to Identify Novel Association Signals among Sub-Threshold Candidates from Genome-Wide Association Studies in Restless Legs Syndrome
Schulte, E. C., Schramm, K., Schurmann, C., Lichtner, P., Herder, C., Roden, M., . . . Winkelmann, J. (2014). Blood <i>cis</i>-eQTL Analysis Fails to Identify Novel Association Signals among Sub-Threshold Candidates from Genome-Wide Association Studies in Restless Legs Syndrome. PLOS ONE, 9(5). doi:10.1371/journal.pone.0098092
Discriminating metastasised from non-metastasised seminoma based on transcriptional changes in primary tumours using NGS
Ruf, C. G., Schmelz, H. -U., Port, M., Wagner, W., Matthies, C., Mueller-Myhsok, B., . . . Abend, M. (2014). Discriminating metastasised from non-metastasised seminoma based on transcriptional changes in primary tumours using NGS. BRITISH JOURNAL OF CANCER, 110(11), 2738-2746. doi:10.1038/bjc.2014.134
Genetic risk prediction and neurobiological understanding of alcoholism
Levey, D. F., Le-Niculescu, H., Frank, J., Ayalew, M., Jain, N., Kirlin, B., . . . Niculescu, A. B. (2014). Genetic risk prediction and neurobiological understanding of alcoholism. TRANSLATIONAL PSYCHIATRY, 4. doi:10.1038/tp.2014.29
Clinically Apparent and Occult Metastasized Seminoma: Almost Indistinguishable on the Transcriptional Level
Ruf, C. G., Port, M., Schmelz, H. -U., Wagner, W., Mueller, F., Senf, S., . . . Abend, M. (2014). Clinically Apparent and Occult Metastasized Seminoma: Almost Indistinguishable on the Transcriptional Level. PLOS ONE, 9(5). doi:10.1371/journal.pone.0095009
A Genome-wide Association Study of Early-Onset Breast Cancer Identifies <i>PFKM</i> as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age
Ahsan, H., Halpern, J., Kibriya, M. G., Pierce, B. L., Tong, L., Gamazon, E., . . . Whittemore, A. S. (2014). A Genome-wide Association Study of Early-Onset Breast Cancer Identifies <i>PFKM</i> as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 23(4), 658-669. doi:10.1158/1055-9965.EPI-13-0340
Genome-wide association study reveals two new risk loci for bipolar disorder
Muehleisen, T. W., Leber, M., Schulze, T. G., Strohmaier, J., Degenhardt, F., Treutlein, J., . . . Cichon, S. (2014). Genome-wide association study reveals two new risk loci for bipolar disorder. NATURE COMMUNICATIONS, 5. doi:10.1038/ncomms4339
Small RNAs in the peripheral blood discriminate metastasized from non-metastasized seminoma
Ruf, C. G., Dinger, D., Port, M., Schmelz, H. -U., Wagner, W., Matthies, C., . . . Abend, M. (2014). Small RNAs in the peripheral blood discriminate metastasized from non-metastasized seminoma. MOLECULAR CANCER, 13. doi:10.1186/1476-4598-13-47
Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk
Bonifaci, N., Colas, E., Serra-Musach, J., Karbalai, N., Brunet, J., Gomez, A., . . . Angel Pujana, M. (2014). Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk. CARCINOGENESIS, 35(3), 578-585. doi:10.1093/carcin/bgt403
Cognitive mechanisms underlying reading and spelling development in five European orthographies
Moll, K., Ramus, F., Bartling, J., Bruder, J., Kunze, S., Neuhoff, N., . . . Landerl, K. (2014). Cognitive mechanisms underlying reading and spelling development in five European orthographies. LEARNING AND INSTRUCTION, 29, 65-77. doi:10.1016/j.learninstruc.2013.09.003
Investigating the genetic variation underlying episodicity in major depressive disorder: Suggestive evidence for a bipolar contribution
Ferentinos, P., Rivera, M., Ising, M., Spain, S. L., Cohen-Woods, S., Butler, A. W., . . . Lewis, C. M. (2014). Investigating the genetic variation underlying episodicity in major depressive disorder: Suggestive evidence for a bipolar contribution. JOURNAL OF AFFECTIVE DISORDERS, 155, 81-89. doi:10.1016/j.jad.2013.10.027
ABCB1 Genetics and Function Determine Penetrance of Antidepressants Into the Brain: Treatment Implications and Open Research Questions
Holsboer, F., Mueller-Myhsok, B., & Uhr, M. (2014). ABCB1 Genetics and Function Determine Penetrance of Antidepressants Into the Brain: Treatment Implications and Open Research Questions. In BIOLOGICAL PSYCHIATRY Vol. 75 (pp. 23S). Retrieved from https://www.webofscience.com/
Allelic differences between Europeans and Chinese for <i>CREB1</i> SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility
Li, M., Luo, X. -J., Rietschel, M., Lewis, C. M., Mattheisen, M., Mueller-Myhsok, B., . . . Su, B. (2014). Allelic differences between Europeans and Chinese for <i>CREB1</i> SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. MOLECULAR PSYCHIATRY, 19(4), 452-461. doi:10.1038/mp.2013.37
Genetic Relationships Between Suicide Attempts, Suicidal Ideation and Major Psychiatric Disorders: A Genome-Wide Association and Polygenic Scoring Study
Mullins, N., Perroud, N., Uher, R., Butler, A. W., Cohen-Woods, S., Rivera, M., . . . Lewis, C. M. (2014). Genetic Relationships Between Suicide Attempts, Suicidal Ideation and Major Psychiatric Disorders: A Genome-Wide Association and Polygenic Scoring Study. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 165(5), 428-437. doi:10.1002/ajmg.b.32247
Genetic Risk Prediction and Neurobiological Understanding of Alcoholism
Levey, D. F., Le-Niculescu, H., Frank, J., Ayalew, M., Jain, N., Kirlin, B., . . . Niculescu, A. B. (2014). Genetic Risk Prediction and Neurobiological Understanding of Alcoholism. In BIOLOGICAL PSYCHIATRY Vol. 75 (pp. 352S). Retrieved from https://www.webofscience.com/
Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort
Becker, J., Czamara, D., Scerri, T. S., Ramus, F., Csepe, V., Talcott, J. B., . . . Schumacher, J. (2014). Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. EUROPEAN JOURNAL OF HUMAN GENETICS, 22(5), 675-680. doi:10.1038/ejhg.2013.199
Genetic modification of 25(OH)D levels in MS
Munger, K., Kochert, K., Fitzgerald, K., Arnason, B., Barkhof, F., Comi, G., . . . Pohl, C. (2014). Genetic modification of 25(OH)D levels in MS. In MULTIPLE SCLEROSIS JOURNAL Vol. 20 (pp. 249). Retrieved from https://www.webofscience.com/
Genetic risk prediction and neurobiological understanding of alcoholism (vol 4, pg e456, 2014)
Levey, D. F., Le-Niculescu, H., Frank, J., Ayalew, M., Jain, N., Kirlin, B., . . . Niculescu, A. B. (2014). Genetic risk prediction and neurobiological understanding of alcoholism (vol 4, pg e456, 2014). TRANSLATIONAL PSYCHIATRY, 4. doi:10.1038/tp.2014.74
Genome-Wide Genotyping Demonstrates a Polygenic Risk Score Associated With White Matter Hyperintensity Volume in CADASIL
Opherk, C., Gonik, M., Duering, M., Malik, R., Jouvent, E., Herve, D., . . . Dichgans, M. (2014). Genome-Wide Genotyping Demonstrates a Polygenic Risk Score Associated With White Matter Hyperintensity Volume in CADASIL. STROKE, 45(4), 968-972. doi:10.1161/STROKEAHA.113.004461
P2RX7-a susceptibility gene for mood disorders?
Aprile-Garcia, F., Metzger, M. W., Dedic, N., Walser, S. M., Jakubcakova, V., Czamara, D., . . . Deussing, J. M. (2014). P2RX7-a susceptibility gene for mood disorders?. In PURINERGIC SIGNALLING Vol. 10 (pp. 718). Retrieved from https://www.webofscience.com/
Restless Legs Syndrome-associated intronic common variant in <i>Meis1</i> alters enhancer function in the developing telencephalon
Spieler, D., Kaffe, M., Knauf, F., Bessa, J., Tena, J. J., Giesert, F., . . . Winkelmann, J. (2014). Restless Legs Syndrome-associated intronic common variant in <i>Meis1</i> alters enhancer function in the developing telencephalon. GENOME RESEARCH, 24(4), 592-603. doi:10.1101/gr.166751.113
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., . . . Drevets, W. (2014). The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. BRAIN IMAGING AND BEHAVIOR, 8(2), 153-182. doi:10.1007/s11682-013-9269-5
2013
Rare variants in PLXNA4 and Parkinson's disease.
Schulte, E. C., Stahl, I., Czamara, D., Ellwanger, D. C., Eck, S., Graf, E., . . . Winkelmann, J. (2013). Rare variants in PLXNA4 and Parkinson's disease.. PloS one, 8(11), e79145. doi:10.1371/journal.pone.0079145
Estimating the heritability of reporting stressful life events captured by common genetic variants.
Power, R. A., Wingenbach, T., Cohen-Woods, S., Uher, R., Ng, M. Y., Butler, A. W., . . . McGuffin, P. (2013). Estimating the heritability of reporting stressful life events captured by common genetic variants.. Psychological medicine, 43(9), 1965-1971. doi:10.1017/s0033291712002589
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
Cross-Disorder Group of the Psychiatric Genomics Consortium., Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., . . . International Inflammatory Bowel Disease Genetics Consortium (IIBDGC). (2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.. Nature genetics, 45(9), 984-994. doi:10.1038/ng.2711
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Anttila, V., Winsvold, B. S., Gormley, P., Kurth, T., Bettella, F., McMahon, G., . . . Palotie, A. (2013). Genome-wide meta-analysis identifies new susceptibility loci for migraine.. Nature genetics, 45(8), 912-917. doi:10.1038/ng.2676
Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.
Kloiber, S., Ripke, S., Kohli, M. A., Reppermund, S., Salyakina, D., Uher, R., . . . Lucae, S. (2013). Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 23(7), 653-662. doi:10.1016/j.euroneuro.2012.08.010
Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach.
Hennings, J. M., Kohli, M. A., Czamara, D., Giese, M., Eckert, A., Wolf, C., . . . Lucae, S. (2013). Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach.. PloS one, 8(6), e64947. doi:10.1371/journal.pone.0064947
Predictors of developmental dyslexia in European orthographies with varying complexity.
Landerl, K., Ramus, F., Moll, K., Lyytinen, H., Leppänen, P. H. T., Lohvansuu, K., . . . Schulte-Körne, G. (2013). Predictors of developmental dyslexia in European orthographies with varying complexity.. Journal of child psychology and psychiatry, and allied disciplines, 54(6), 686-694. doi:10.1111/jcpp.12029
Variants within the GABA transaminase (ABAT) gene region are associated with somatosensory evoked EEG potentials in families at high risk for affective disorders.
Wegerer, M., Adena, S., Pfennig, A., Czamara, D., Sailer, U., Bettecken, T., . . . Ising, M. (2013). Variants within the GABA transaminase (ABAT) gene region are associated with somatosensory evoked EEG potentials in families at high risk for affective disorders.. Psychological medicine, 43(6), 1207-1217. doi:10.1017/s0033291711002923
Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies.
Czamara, D., Tiesler, C. M. T., Kohlböck, G., Berdel, D., Hoffmann, B., Bauer, C. -P., . . . Heinrich, J. (2013). Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies.. PloS one, 8(5), e63859. doi:10.1371/journal.pone.0063859
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.
Mehta, D., Mehta, D., Klengel, T., Conneely, K. N., Smith, A. K., Altmann, A., . . . Binder, E. B. (2013). Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.. Proceedings of the National Academy of Sciences of the United States of America, 110(20), 8302-8307. doi:10.1073/pnas.1217750110
Erratum: Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility
Li, M., Luo, X. -J., Rietschel, M., Lewis, C. M., Mattheisen, M., Müller-Myhsok, B., . . . Wright, M. J. (2014). Erratum: Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular Psychiatry, 19(4), 527. doi:10.1038/mp.2013.73
A mega-analysis of genome-wide association studies for major depressive disorder.
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium., Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., . . . Sullivan, P. F. (2013). A mega-analysis of genome-wide association studies for major depressive disorder.. Molecular psychiatry, 18(4), 497-511. doi:10.1038/mp.2012.21
Dilution of candidates: the case of iron-related genes in restless legs syndrome.
Oexle, K., Schormair, B., Ried, J. S., Czamara, D., Heim, K., Frauscher, B., . . . Winkelmann, J. (2013). Dilution of candidates: the case of iron-related genes in restless legs syndrome.. European journal of human genetics : EJHG, 21(4), 410-414. doi:10.1038/ejhg.2012.193
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
Garcia-Closas, M., Couch, F. J., Lindstrom, S., Michailidou, K., Schmidt, M. K., Brook, M. N., . . . Kraft, P. (2013). Genome-wide association studies identify four ER negative-specific breast cancer risk loci.. Nature genetics, 45(4), 392-398e2. doi:10.1038/ng.2561
Genome-wide linkage analysis is a powerful prenatal diagnostic tool in families with unknown genetic defects.
Arélin, M., Schulze, B., Müller-Myhsok, B., Horn, D., Diers, A., Uhlenberg, B., . . . Hoffmann, K. (2013). Genome-wide linkage analysis is a powerful prenatal diagnostic tool in families with unknown genetic defects.. European journal of human genetics : EJHG, 21(4), 367-372. doi:10.1038/ejhg.2012.198
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Michailidou, K., Hall, P., Gonzalez-Neira, A., Ghoussaini, M., Dennis, J., Milne, R. L., . . . Easton, D. F. (2013). Large-scale genotyping identifies 41 new loci associated with breast cancer risk.. Nature genetics, 45(4), 353-361e2. doi:10.1038/ng.2563
Cost-effective GPU-grid for genome-wide epistasis calculations.
Pütz, B., Kam-Thong, T., Karbalai, N., Altmann, A., & Müller-Myhsok, B. (2013). Cost-effective GPU-grid for genome-wide epistasis calculations.. Methods of information in medicine, 52(1), 91-95. doi:10.3414/me11-02-0049
A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.
Ludwig, K. U., Sämann, P., Alexander, M., Becker, J., Bruder, J., Moll, K., . . . Czamara, D. (2013). A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.. Translational psychiatry, 3, e229. doi:10.1038/tp.2012.148
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.
GENDEP Investigators., MARS Investigators., & STAR*D Investigators. (2013). Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.. The American journal of psychiatry, 170(2), 207-217. doi:10.1176/appi.ajp.2012.12020237
Migraine without aura: genome-wide association analysis identifies several novel susceptibility
de Vries, B., Freilinger, T., Anttila, V., Malik, R., Kallela, M., Terwindt, G. M., . . . van den Maagdenberg, A. M. J. M. (2013). Migraine without aura: genome-wide association analysis identifies several novel susceptibility. The Journal of Headache and Pain, 14(S1). doi:10.1186/1129-2377-14-s1-p18
Migraine without aura: genome-wide association analysis identifies several novel susceptibility
De Vries, B. L., Freilinger, T., Anttila, V., Malik, R., Terwindt, G. M., Pozo-Rosich, P., . . . van den Maagdenberg, A. M. J. (2013). Migraine without aura: genome-wide association analysis identifies several novel susceptibility. The Journal of Headache and Pain, 14(S1). doi:10.1186/1129-2377-14-s1-p21
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.
Allebrandt, K. V., Amin, N., Müller-Myhsok, B., Esko, T., Teder-Laving, M., Azevedo, R. V. D. M., . . . Roenneberg, T. (2013). A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.. Molecular psychiatry, 18(1), 122-132. doi:10.1038/mp.2011.142
No effect of susceptibility genes on the course of multiple sclerosis as measured by magnetic resonance imaging
Muehlau, M., Filippi, M., Barkhof, F., Schwenke, S., Igl, W., Sandbrink, R., . . . Hemmer, B. (2013). No effect of susceptibility genes on the course of multiple sclerosis as measured by magnetic resonance imaging. In MULTIPLE SCLEROSIS JOURNAL Vol. 19 (pp. 379-380). Retrieved from https://www.webofscience.com/
2012
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.
Glas, J., Seiderer, J., Czamara, D., Pasciuto, G., Diegelmann, J., Wetzke, M., . . . Brand, S. (2012). PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.. PloS one, 7(12), e52873. doi:10.1371/journal.pone.0052873
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Siddiq, A., Couch, F. J., Chen, G. K., Lindström, S., Eccles, D., Millikan, R. C., . . . Vachon, C. M. (2012). A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.. Human molecular genetics, 21(24), 5373-5384. doi:10.1093/hmg/dds381
Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.
Li, M., Wang, Y., Zheng, X. -B., Ikeda, M., Iwata, N., Luo, X. -J., . . . MooDS Consortium. (2012). Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.. Schizophrenia research, 142(1-3), 200-205. doi:10.1016/j.schres.2012.10.008
Rare variants in TMEM132D in a case-control sample for panic disorder.
Quast, C., Altmann, A., Weber, P., Arloth, J., Bader, D., Heck, A., . . . Binder, E. B. (2012). Rare variants in TMEM132D in a case-control sample for panic disorder.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 159B(8), 896-907. doi:10.1002/ajmg.b.32096
The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety.
Gonik, M., Frank, E., Keßler, M. S., Czamara, D., Bunck, M., Yen, Y. -C., . . . Czibere, L. (2012). The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety.. BMC genomics, 13, 579. doi:10.1186/1471-2164-13-579
A beginners guide to SNP calling from high-throughput DNA-sequencing data.
Altmann, A., Weber, P., Bader, D., Preuss, M., Binder, E. B., & Müller-Myhsok, B. (2012). A beginners guide to SNP calling from high-throughput DNA-sequencing data.. Human genetics, 131(10), 1541-1554. doi:10.1007/s00439-012-1213-z
Dissecting the genetic heterogeneity of depression through age at onset.
Power, R. A., Keers, R., Ng, M. Y., Butler, A. W., Uher, R., Cohen-Woods, S., . . . Lewis, C. M. (2012). Dissecting the genetic heterogeneity of depression through age at onset.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 159B(7), 859-868. doi:10.1002/ajmg.b.32093
Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.
Meier, S., Mattheisen, M., Vassos, E., Strohmaier, J., Treutlein, J., Josef, F., . . . Szelinger, S. (2012). Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.. Translational psychiatry, 2, e165. doi:10.1038/tp.2012.81
Replication and meta-analysis of TMEM132D gene variants in panic disorder.
Erhardt, A., Akula, N., Schumacher, J., Czamara, D., Karbalai, N., Müller-Myhsok, B., . . . Binder, E. B. (2012). Replication and meta-analysis of TMEM132D gene variants in panic disorder.. Translational psychiatry, 2, e156. doi:10.1038/tp.2012.85
Restless legs syndrome in Czech patients with multiple sclerosis: an epidemiological and genetic study.
Vávrová, J., Kemlink, D., Sonka, K., Havrdová, E., Horáková, D., Pardini, B., . . . Winkelmann, J. (2012). Restless legs syndrome in Czech patients with multiple sclerosis: an epidemiological and genetic study.. Sleep medicine, 13(7), 848-851. doi:10.1016/j.sleep.2012.03.012
Evidence for the involvement of ZNF804A in cognitive processes of relevance to reading and spelling.
Becker, J., Czamara, D., Hoffmann, P., Landerl, K., Blomert, L., Brandeis, D., . . . Schumacher, J. (2012). Evidence for the involvement of ZNF804A in cognitive processes of relevance to reading and spelling.. Translational psychiatry, 2, e136. doi:10.1038/tp.2012.62
The aromatase gene CYP19A1: several genetic and functional lines of evidence supporting a role in reading, speech and language.
Anthoni, H., Sucheston, L. E., Lewis, B. A., Tapia-Páez, I., Fan, X., Zucchelli, M., . . . Kere, J. (2012). The aromatase gene CYP19A1: several genetic and functional lines of evidence supporting a role in reading, speech and language.. Behavior genetics, 42(4), 509-527. doi:10.1007/s10519-012-9532-3
Genome-wide association analysis identifies susceptibility loci for migraine without aura.
Freilinger, T., Anttila, V., de Vries, B., Malik, R., Kallela, M., Terwindt, G. M., . . . International Headache Genetics Consortium. (2012). Genome-wide association analysis identifies susceptibility loci for migraine without aura.. Nature genetics, 44(7), 777-782. doi:10.1038/ng.2307
Erratum: Imaging genetics of FOXP2 in dyslexia
Wilcke, A., Jana Burkhardt, C. L., Alexander, M., Wolf, C., Quente, E., Ahnert, P., . . . Kirsten, H. (2012). Erratum: Imaging genetics of FOXP2 in dyslexia. European Journal of Human Genetics, 20(6), 714. doi:10.1038/ejhg.2012.31
Evidence for the late MMN as a neurophysiological endophenotype for dyslexia.
Neuhoff, N., Bruder, J., Bartling, J., Warnke, A., Remschmidt, H., Müller-Myhsok, B., & Schulte-Körne, G. (2012). Evidence for the late MMN as a neurophysiological endophenotype for dyslexia.. PloS one, 7(5), e34909. doi:10.1371/journal.pone.0034909
Identification of common variants associated with human hippocampal and intracranial volumes.
Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Senstad, R. E., Winkler, A. M., . . . Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium. (2012). Identification of common variants associated with human hippocampal and intracranial volumes.. Nature genetics, 44(5), 552-561. doi:10.1038/ng.2250
Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.
Degenhardt, F., Priebe, L., Herms, S., Mattheisen, M., Mühleisen, T. W., Meier, S., . . . Cichon, S. (2012). Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 159B(3), 263-273. doi:10.1002/ajmg.b.32034
Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.
Menke, A., Sämann, P., Kloiber, S., Czamara, D., Lucae, S., Hennings, J., . . . Binder, E. B. (2012). Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.. Psychoneuroendocrinology, 37(4), 565-575. doi:10.1016/j.psyneuen.2011.09.003
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis.
Babron, M. -C., Perdry, H., Handel, A. E., Ramagopalan, S. V., Damotte, V., Fontaine, B., . . . Clerget-Darpoux, F. (2012). Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis.. European journal of human genetics : EJHG, 20(3), 321-325. doi:10.1038/ejhg.2011.197
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.
International Stroke Genetics Consortium (ISGC)., Wellcome Trust Case Control Consortium 2 (WTCCC2)., Bellenguez, C., Bevan, S., Gschwendtner, A., Spencer, C. C. A., . . . Markus, H. S. (2012). Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.. Nature genetics, 44(3), 328-333. doi:10.1038/ng.1081
Genome-wide association study of antidepressant treatment-emergent suicidal ideation.
Menke, A., Domschke, K., Czamara, D., Klengel, T., Hennings, J., Lucae, S., . . . Binder, E. B. (2012). Genome-wide association study of antidepressant treatment-emergent suicidal ideation.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(3), 797-807. doi:10.1038/npp.2011.257
Genome-wide association analysis identifies three new breast cancer susceptibility loci.
Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., Dicks, E., . . . Easton, D. F. (2012). Genome-wide association analysis identifies three new breast cancer susceptibility loci.. Nature genetics, 44(3), 312-318. doi:10.1038/ng.1049
ANK3 and CACNA1C--missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples.
Kloiber, S., Czamara, D., Karbalai, N., Müller-Myhsok, B., Hennings, J., Holsboer, F., & Lucae, S. (2012). ANK3 and CACNA1C--missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples.. Journal of psychiatric research, 46(8), 973-979. doi:10.1016/j.jpsychires.2012.04.017
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.
Menke, A., Arloth, J., Pütz, B., Weber, P., Klengel, T., Mehta, D., . . . Binder, E. B. (2012). Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 37(6), 1455-1464. doi:10.1038/npp.2011.331
Don't give up on GWAS.
Sullivan, P., & 96 Psychiatric Genetics Investigators. (2012). Don't give up on GWAS.. Molecular psychiatry, 17(1), 2-3. doi:10.1038/mp.2011.94
Erratum: Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients
Menke, A., Arloth, J., Pütz, B., Weber, P., Klengel, T., Mehta, D., . . . Binder, E. B. (2012). Erratum: Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients. Neuropsychopharmacology, 37(8), 1972. doi:10.1038/npp.2012.21
GLIDE: GPU-based linear regression for detection of epistasis.
Kam-Thong, T., Azencott, C. -A., Cayton, L., Pütz, B., Altmann, A., Karbalai, N., . . . Borgwardt, K. M. (2012). GLIDE: GPU-based linear regression for detection of epistasis.. Human heredity, 73(4), 220-236. doi:10.1159/000341885
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
Frank, J., Cichon, S., Treutlein, J., Ridinger, M., Mattheisen, M., Hoffmann, P., . . . Rietschel, M. (2012). Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.. Addiction biology, 17(1), 171-180. doi:10.1111/j.1369-1600.2011.00395.x
Imaging genetics of FOXP2 in dyslexia.
Wilcke, A., Ligges, C., Burkhardt, J., Alexander, M., Wolf, C., Quente, E., . . . Kirsten, H. (2012). Imaging genetics of FOXP2 in dyslexia.. European journal of human genetics : EJHG, 20(2), 224-229. doi:10.1038/ejhg.2011.160
Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients.
Weber, F., Cepok, S., Wolf, C., Berthele, A., Uhr, M., Bettecken, T., . . . Hemmer, B. (2012). Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients.. The pharmacogenomics journal, 12(3), 238-245. doi:10.1038/tpj.2011.14
Using affected sib-pairs to uncover rare disease variants.
Perdry, H., Müller-Myhsok, B., & Clerget-Darpoux, F. (2012). Using affected sib-pairs to uncover rare disease variants.. Human heredity, 74(3-4), 129-141. doi:10.1159/000346788
2011
Efficient branch-and-bound techniques for two-locus association mapping
Klotzbücher, K., Kobayashi, Y., Shervashidze, N., Stegle, O., Müller-Myhsok, B., Weigel, D., & Borgwardt, K. (2011). Efficient branch-and-bound techniques for two-locus association mapping. BMC Bioinformatics, 12(S11). doi:10.1186/1471-2105-12-s11-a3
Risk conferring genes in multiple sclerosis.
Nischwitz, S., Müller-Myhsok, B., & Weber, F. (2011). Risk conferring genes in multiple sclerosis.. FEBS letters, 585(23), 3789-3797. doi:10.1016/j.febslet.2011.03.037
Evidence for associations between MDGA2 polymorphisms and harm avoidance: replication and extension of a genome-wide association finding.
Heck, A., Pfister, H., Czamara, D., Müller-Myhsok, B., Pütz, B., Lucae, S., . . . Ising, M. (2011). Evidence for associations between MDGA2 polymorphisms and harm avoidance: replication and extension of a genome-wide association finding.. Psychiatric genetics, 21(5), 257-260. doi:10.1097/ypg.0b013e3283457bfb
Somatization in major depression--clinical features and genetic associations.
Klengel, T., Heck, A., Pfister, H., Brückl, T., Hennings, J. M., Menke, A., . . . Ising, M. (2011). Somatization in major depression--clinical features and genetic associations.. Acta psychiatrica Scandinavica, 124(4), 317-328. doi:10.1111/j.1600-0447.2011.01743.x
BDNF and NTRK2 polymorphisms and antidepressant treatment outcome
Hennings, J. M., Kohli, M. A., Czamara, D., Wolf, C., Domschke, K., Arolt, V., . . . Lucae, S. (2011). BDNF and NTRK2 polymorphisms and antidepressant treatment outcome. Pharmacopsychiatry, 44(06). doi:10.1055/s-0031-1292496
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.
Glas, J., Seiderer, J., Fischer, D., Tengler, B., Pfennig, S., Wetzke, M., . . . Brand, S. (2011). Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.. Inflammatory bowel diseases, 17(9), 1917-1924. doi:10.1002/ibd.21562
The non-synonymous P2RX7 SNP rs2230912 is associated with affective disorders: Results from an association study in major depression and from a meta-analysis
Lucae, S., Czamara, D., Uhr, M., Ising, M., Holsboer, F., & Müller-Myhsok, B. (2011). The non-synonymous P2RX7 SNP rs2230912 is associated with affective disorders: Results from an association study in major depression and from a meta-analysis. Pharmacopsychiatry, 44(06). doi:10.1055/s-0031-1292515
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.
Mehta, D., Mehta, D., Gonik, M., Klengel, T., Rex-Haffner, M., Menke, A., . . . Binder, E. B. (2011). Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.. Archives of general psychiatry, 68(9), 901-910. doi:10.1001/archgenpsychiatry.2011.50
An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction.
Moskvina, V., Craddock, N., Müller-Myhsok, B., Kam-Thong, T., Green, E., Holmans, P., . . . O'Donovan, M. C. (2011). An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction.. Biological psychiatry, 70(2), 198-203. doi:10.1016/j.biopsych.2011.01.034
Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs.
Kam-Thong, T., Pütz, B., Karbalai, N., Müller-Myhsok, B., & Borgwardt, K. (2011). Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs.. Bioinformatics (Oxford, England), 27(13), i214-i221. doi:10.1093/bioinformatics/btr218
Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.
Winkelmann, J., Czamara, D., Schormair, B., Knauf, F., Schulte, E. C., Trenkwalder, C., . . . Meitinger, T. (2011). Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.. PLoS genetics, 7(7), e1002171. doi:10.1371/journal.pgen.1002171
MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease.
Schormair, B., Plag, J., Kaffe, M., Gross, N., Czamara, D., Samtleben, W., . . . Winkelmann, J. (2011). MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease.. Journal of medical genetics, 48(7), 462-466. doi:10.1136/jmg.2010.087858
vipR: variant identification in pooled DNA using R.
Altmann, A., Weber, P., Quast, C., Rex-Haffner, M., Binder, E. B., & Müller-Myhsok, B. (2011). vipR: variant identification in pooled DNA using R.. Bioinformatics (Oxford, England), 27(13), i77-i84. doi:10.1093/bioinformatics/btr205
More CLEC16A gene variants associated with multiple sclerosis.
Nischwitz, S., Cepok, S., Kroner, A., Wolf, C., Knop, M., Müller-Sarnowski, F., . . . Weber, F. (2011). More CLEC16A gene variants associated with multiple sclerosis.. Acta neurologica Scandinavica, 123(6), 400-406. doi:10.1111/j.1600-0404.2010.01421.x
TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies.
Erhardt, A., Czibere, L., Roeske, D., Lucae, S., Unschuld, P. G., Ripke, S., . . . Binder, E. B. (2011). TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies.. Molecular psychiatry, 16(6), 647-663. doi:10.1038/mp.2010.41
CEACAM6 gene variants in inflammatory bowel disease.
Glas, J., Seiderer, J., Fries, C., Tillack, C., Pfennig, S., Weidinger, M., . . . Brand, S. (2011). CEACAM6 gene variants in inflammatory bowel disease.. PloS one, 6(4), e19319. doi:10.1371/journal.pone.0019319
The neuronal transporter gene SLC6A15 confers risk to major depression.
Kohli, M. A., Lucae, S., Saemann, P. G., Schmidt, M. V., Demirkan, A., Hek, K., . . . Binder, E. B. (2011). The neuronal transporter gene SLC6A15 confers risk to major depression.. Neuron, 70(2), 252-265. doi:10.1016/j.neuron.2011.04.005
EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units.
Kam-Thong, T., Czamara, D., Tsuda, K., Borgwardt, K., Lewis, C. M., Erhardt-Lehmann, A., . . . Müller-Myhsok, B. (2011). EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units.. European journal of human genetics : EJHG, 19(4), 465-471. doi:10.1038/ejhg.2010.196
Role of PPARG gene variants in inflammatory bowel disease.
Glas, J., Seiderer, J., Markus, C., Pfennig, S., Wetzke, M., Paschos, E., . . . Brand, S. (2011). Role of PPARG gene variants in inflammatory bowel disease.. Inflammatory bowel diseases, 17(4), 1057-1058. doi:10.1002/ibd.21425
Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder
Cichon, S., Mühleisen, T. W., Degenhardt, F. A., Mattheisen, M., Miró, X., Strohmaier, J., . . . Nöthen, M. M. (2011). Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder. The American Journal of Human Genetics, 88(3), 396. doi:10.1016/j.ajhg.2011.03.001
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.
Cichon, S., Mühleisen, T. W., Degenhardt, F. A., Mattheisen, M., Miró, X., Strohmaier, J., . . . Nöthen, M. M. (2011). Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.. American journal of human genetics, 88(3), 372-381. doi:10.1016/j.ajhg.2011.01.017
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.
Oexle, K., Ried, J. S., Hicks, A. A., Tanaka, T., Hayward, C., Bruegel, M., . . . Meitinger, T. (2011). Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.. Human molecular genetics, 20(5), 1042-1047. doi:10.1093/hmg/ddq538
P.1.006 Screening for rare variants in TMEM132D: a candidate gene from genome-wide association studies in anxiety disorders
Quast, C., Altmann, A., Weber, P., Rex-Haffner, M., Erhardt, A., Müller-Myhsok, B., & Binder, E. B. (2011). P.1.006 Screening for rare variants in TMEM132D: a candidate gene from genome-wide association studies in anxiety disorders. European Neuropsychopharmacology, 21, S6-S7. doi:10.1016/s0924-977x(11)70007-4
Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility.
Couturier, N., Bucciarelli, F., Nurtdinov, R. N., Debouverie, M., Lebrun-Frenay, C., Defer, G., . . . Brassat, D. (2011). Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility.. Brain : a journal of neurology, 134(Pt 3), 693-703. doi:10.1093/brain/awr010
Association of a rare variant with mismatch negativity in a region between KIAA0319 and DCDC2 in dyslexia.
Czamara, D., Bruder, J., Becker, J., Bartling, J., Hoffmann, P., Ludwig, K. U., . . . Schulte-Körne, G. (2011). Association of a rare variant with mismatch negativity in a region between KIAA0319 and DCDC2 in dyslexia.. Behavior genetics, 41(1), 110-119. doi:10.1007/s10519-010-9413-6
First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.
Roeske, D., Ludwig, K. U., Neuhoff, N., Becker, J., Bartling, J., Bruder, J., . . . Schulte-Körne, G. (2011). First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.. Molecular psychiatry, 16(1), 97-107. doi:10.1038/mp.2009.102
Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks.
Sarapas, C., Cai, G., Bierer, L. M., Golier, J. A., Galea, S., Ising, M., . . . Yehuda, R. (2011). Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks.. Disease markers, 30(2-3), 101-110. doi:10.3233/dma-2011-0764
Genomewide association scan of suicidal thoughts and behaviour in major depression.
Schosser, A., Butler, A. W., Ising, M., Perroud, N., Uher, R., Ng, M. Y., . . . Lewis, C. M. (2011). Genomewide association scan of suicidal thoughts and behaviour in major depression.. PloS one, 6(7), e20690. doi:10.1371/journal.pone.0020690
Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21.
König, I. R., Schumacher, J., Hoffmann, P., Kleensang, A., Ludwig, K. U., Grimm, T., . . . Schulte-Körne, G. (2011). Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156B(1), 36-43. doi:10.1002/ajmg.b.31135
2010
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.
Glas, J., Seiderer, J., Tillack, C., Pfennig, S., Beigel, F., Jürgens, M., . . . Brand, S. (2010). The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.. PloS one, 5(12), e14466. doi:10.1371/journal.pone.0014466
Erratum: Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
Kloiber, S., Kohli, M. A., Brueckl, T., Ripke, S., Ising, M., Uhr, M., . . . Lucae, S. (2010). Erratum: Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Molecular Psychiatry, 15(11), 1123. doi:10.1038/mp.2009.8
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
Nischwitz, S., Cepok, S., Kroner, A., Wolf, C., Knop, M., Müller-Sarnowski, F., . . . Weber, F. (2010). Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.. Journal of neuroimmunology, 227(1-2), 162-166. doi:10.1016/j.jneuroim.2010.06.003
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.
Anttila, V., Stefansson, H., Kallela, M., Todt, U., Terwindt, G. M., Calafato, M. S., . . . International Headache Genetics Consortium. (2010). Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.. Nature genetics, 42(10), 869-873. doi:10.1038/ng.652
Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.
Rietschel, M., Mattheisen, M., Frank, J., Treutlein, J., Degenhardt, F., Breuer, R., . . . Cichon, S. (2010). Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.. Biological psychiatry, 68(6), 578-585. doi:10.1016/j.biopsych.2010.05.038
Brain–gene interactions in dyslexia
Schulte-Körne, G., Bruder, J., Neuhoff, N., Roeske, D., Hoffmann, P., Ludwig, K., . . . Müller-Myhsok, B. (2010). Brain–gene interactions in dyslexia. International Journal of Psychophysiology, 77(3), 229-230. doi:10.1016/j.ijpsycho.2010.06.331
Cortisol levels and gene expression changes in posttraumatic stress disorder: the role of endophenotypes in determining common biological pathways in psychiatric disorders
Mehta, D., Gonik, M., Klengel, T., Rex-Haffner, M., Mercer-Butze, K., Bradley, B., . . . Binder, E. (n.d.). Cortisol levels and gene expression changes in posttraumatic stress disorder: the role of endophenotypes in determining common biological pathways in psychiatric disorders. Experimental and Clinical Endocrinology & Diabetes, 118(08). doi:10.1055/s-0030-1267017
P.2.h.001 Polymorphisms in the BDNF gene are associated with antidepressant treatment response
Hennings, J., Kohli, M., Heck, A., Roeske, D., Brückl, T., Klengel, T., . . . Lucae, S. (2010). P.2.h.001 Polymorphisms in the BDNF gene are associated with antidepressant treatment response. European Neuropsychopharmacology, 20, S427-S428. doi:10.1016/s0924-977x(10)70617-9
Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways.
Ditzen, C., Varadarajulu, J., Czibere, L., Gonik, M., Targosz, B. S., Hambsch, B., . . . Turck, C. W. (2010). Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways.. Molecular psychiatry, 15(7), 702-711. doi:10.1038/mp.2008.146
Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression.
Kloiber, S., Kohli, M. A., Brueckl, T., Ripke, S., Ising, M., Uhr, M., . . . Lucae, S. (2010). Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression.. Molecular psychiatry, 15(7), 736-747. doi:10.1038/mp.2008.142
Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients.
Hemminki, K., Müller-Myhsok, B., Lichtner, P., Engel, C., Chen, B., Burwinkel, B., . . . Meindl, A. (2010). Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients.. International journal of cancer, 126(12), 2858-2862. doi:10.1002/ijc.24986
CLOCK gene variants associate with sleep duration in two independent populations.
Allebrandt, K. V., Teder-Laving, M., Akyol, M., Pichler, I., Müller-Myhsok, B., Pramstaller, P., . . . Roenneberg, T. (2010). CLOCK gene variants associate with sleep duration in two independent populations.. Biological psychiatry, 67(11), 1040-1047. doi:10.1016/j.biopsych.2009.12.026
Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response.
Unschuld, P. G., Ising, M., Roeske, D., Erhardt, A., Specht, M., Kloiber, S., . . . Binder, E. B. (2010). Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(7), 1583-1592. doi:10.1038/npp.2010.30
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.
Muglia, P., Tozzi, F., Galwey, N. W., Francks, C., Upmanyu, R., Kong, X. Q., . . . Roses, A. D. (2010). Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.. Molecular psychiatry, 15(6), 589-601. doi:10.1038/mp.2008.131
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
Meindl, A., Hellebrand, H., Wiek, C., Erven, V., Wappenschmidt, B., Niederacher, D., . . . Hanenberg, H. (2010). Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.. Nature genetics, 42(5), 410-414. doi:10.1038/ng.569
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.
Glas, J., Seiderer, J., Nagy, M., Fries, C., Beigel, F., Weidinger, M., . . . Brand, S. (2010). Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.. PloS one, 5(4), e10373. doi:10.1371/journal.pone.0010373
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.
Kohli, M. A., Salyakina, D., Pfennig, A., Lucae, S., Horstmann, S., Menke, A., . . . Binder, E. B. (2010). Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.. Archives of general psychiatry, 67(4), 348-359. doi:10.1001/archgenpsychiatry.2009.201
Variation in GRIN2B contributes to weak performance in verbal short-term memory in children with dyslexia.
Ludwig, K. U., Roeske, D., Herms, S., Schumacher, J., Warnke, A., Plume, E., . . . Hoffmann, P. (2010). Variation in GRIN2B contributes to weak performance in verbal short-term memory in children with dyslexia.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 153B(2), 503-511. doi:10.1002/ajmg.b.31007
An extensive comparison of quantitative trait Loci mapping methods.
Kleensang, A., Franke, D., Alcaïs, A., Abel, L., Müller-Myhsok, B., & Ziegler, A. (2010). An extensive comparison of quantitative trait Loci mapping methods.. Human heredity, 69(3), 202-211. doi:10.1159/000289596
Genome-wide association study of PR interval.
Pfeufer, A., van Noord, C., Marciante, K. D., Arking, D. E., Larson, M. G., Smith, A. V., . . . Heckbert, S. R. (2010). Genome-wide association study of PR interval.. Nature genetics, 42(2), 153-159. doi:10.1038/ng.517
Lysyl oxidase-like 1 gene polymorphisms in German patients with normal tension glaucoma, pigmentary glaucoma and exfoliation glaucoma.
Wolf, C., Gramer, E., Müller-Myhsok, B., Pasutto, F., Gramer, G., Wissinger, B., & Weisschuh, N. (2010). Lysyl oxidase-like 1 gene polymorphisms in German patients with normal tension glaucoma, pigmentary glaucoma and exfoliation glaucoma.. Journal of glaucoma, 19(2), 136-141. doi:10.1097/ijg.0b013e31819f9330
Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.
Horstmann, S., Lucae, S., Menke, A., Hennings, J. M., Ising, M., Roeske, D., . . . Binder, E. B. (2010). Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 35(3), 727-740. doi:10.1038/npp.2009.180
Mitochondrial haplogroup U is associated with a reduced risk to develop exfoliation glaucoma in the German population.
Wolf, C., Gramer, E., Müller-Myhsok, B., Pasutto, F., Wissinger, B., & Weisschuh, N. (2010). Mitochondrial haplogroup U is associated with a reduced risk to develop exfoliation glaucoma in the German population.. BMC genetics, 11, 8. doi:10.1186/1471-2156-11-8
HTR2A gene variation is involved in antidepressant treatment response.
Lucae, S., Ising, M., Horstmann, S., Baune, B. T., Arolt, V., Müller-Myhsok, B., . . . Domschke, K. (2010). HTR2A gene variation is involved in antidepressant treatment response.. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 20(1), 65-68. doi:10.1016/j.euroneuro.2009.08.006
2009
Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders.
Unschuld, P. G., Ising, M., Specht, M., Erhardt, A., Ripke, S., Heck, A., . . . Binder, E. B. (2009). Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 150B(8), 1100-1109. doi:10.1002/ajmg.b.30938
Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks.
Yehuda, R., Cai, G., Golier, J. A., Sarapas, C., Galea, S., Ising, M., . . . Buxbaum, J. D. (2009). Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks.. Biological psychiatry, 66(7), 708-711. doi:10.1016/j.biopsych.2009.02.034
Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study.
Wolf, C., Gramer, E., Müller-Myhsok, B., Pasutto, F., Reinthal, E., Wissinger, B., & Weisschuh, N. (2009). Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study.. BMC medical genetics, 10, 91. doi:10.1186/1471-2350-10-91
A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression
Ising, M., Lucae, S., Binder, E. B., Bettecken, T., Uhr, M., Ripke, S., . . . Müller-Myhsok, B. (2009). A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240141
A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.
Ising, M., Lucae, S., Binder, E. B., Bettecken, T., Uhr, M., Ripke, S., . . . Müller-Myhsok, B. (2009). A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.. Archives of general psychiatry, 66(9), 966-975. doi:10.1001/archgenpsychiatry.2009.95
Polymorphisms in the gene encoding the neuropeptide galanin are associated with HPA-axis dysregulation and symptome severity in major-depressive- and anxiety-disorder patients
Unschuld, P. G., Ising, M., Roeske, D., Erhardt, A., Specht, M., Ripke, S., . . . Binder, E. B. (2009). Polymorphisms in the gene encoding the neuropeptide galanin are associated with HPA-axis dysregulation and symptome severity in major-depressive- and anxiety-disorder patients. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240238
Polymorphisms in tryptophan hydroxylase 2 leading to decreased serotonergic activity contribute to elevated risk for metabolic syndrome in depression
Kloiber, S., Kohli, M. A., Brückl, T., Ripke, S., Ising, M., Uhr, M., . . . Lucae, S. (2009). Polymorphisms in tryptophan hydroxylase 2 leading to decreased serotonergic activity contribute to elevated risk for metabolic syndrome in depression. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240151
Polymorphisms within the 4-aminobutyrate aminotransferase gene are associated with long-latency somatosensory potentials in families vulnerable for affective disorders
Wegerer, M., Adena, S., Binder, E. B., Huber, J., Sailer, U., Bettecken, T., . . . Ising, M. (2009). Polymorphisms within the 4-aminobutyrate aminotransferase gene are associated with long-latency somatosensory potentials in families vulnerable for affective disorders. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240248
Proteomic genotyping in a mouse model of trait anxiety exposes disease relevant pathways
Ditzen, C., Varadarajulu, J., Czibere, L., Gonik, M., Bunck, M., Teplytska, L., . . . Turck, C. W. (2009). Proteomic genotyping in a mouse model of trait anxiety exposes disease relevant pathways. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240101
The neuronal transporter gene SLC6A15 confers risk to major depression
Lucae, S., Kohli, M. A., Schmidt, M. V., Sämann, P. G., Demirkan, A., Hek, K., . . . Binder, E. B. (2009). The neuronal transporter gene SLC6A15 confers risk to major depression. Pharmacopsychiatry, 42(05). doi:10.1055/s-0029-1240169
Supporting evidence for LRRTM1 imprinting effects in schizophrenia.
Ludwig, K. U., Mattheisen, M., Mühleisen, T. W., Roeske, D., Schmäl, C., Breuer, R., . . . Cichon, S. (2009). Supporting evidence for LRRTM1 imprinting effects in schizophrenia.. Molecular psychiatry, 14(8), 743-745. doi:10.1038/mp.2009.28
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.
Török, H. P., Glas, J., Endres, I., Tonenchi, L., Teshome, M. Y., Wetzke, M., . . . Brand, S. (2009). Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.. The American journal of gastroenterology, 104(7), 1723-1733. doi:10.1038/ajg.2009.184
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.
Glas, J., Stallhofer, J., Ripke, S., Wetzke, M., Pfennig, S., Klein, W., . . . Brand, S. (2009). Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.. The American journal of gastroenterology, 104(7), 1737-1744. doi:10.1038/ajg.2009.163
Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking.
Heck, A., Lieb, R., Ellgas, A., Pfister, H., Lucae, S., Roeske, D., . . . Ising, M. (2009). Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking.. Genes, brain, and behavior, 8(4), 464-472. doi:10.1111/j.1601-183x.2009.00494.x
The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.
Thoeringer, C. K., Ripke, S., Unschuld, P. G., Lucae, S., Ising, M., Bettecken, T., . . . Erhardt, A. (2009). The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.. Journal of neural transmission (Vienna, Austria : 1996), 116(6), 649-657. doi:10.1007/s00702-008-0075-y
205 Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis with Il23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease
Stallhofer, J., Glas, J., Koletzko, S., Folwaczny, M., Göke, B., Ochsenkühn, T., . . . Brand, S. (2009). 205 Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis with Il23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease. Gastroenterology, 136(5), A-38. doi:10.1016/s0016-5085(09)60176-1
Replication of restless legs syndrome loci in three European populations.
Kemlink, D., Polo, O., Frauscher, B., Gschliesser, V., Högl, B., Poewe, W., . . . Winkelmann, J. (2009). Replication of restless legs syndrome loci in three European populations.. Journal of medical genetics, 46(5), 315-318. doi:10.1136/jmg.2008.062992
S1188 Ethnic Differences in the Genetic Susceptibility to Crohn's Disease: Functional PPARG Gene Variants Are Not Associated with Susceptibility to Inflammatory Bowel Disease in the German Population
Diegelmann, J., Glas, J., Török, H. -P., Seiderer, J., Göke, B., Folwaczny, M., . . . Brand, S. (2009). S1188 Ethnic Differences in the Genetic Susceptibility to Crohn's Disease: Functional PPARG Gene Variants Are Not Associated with Susceptibility to Inflammatory Bowel Disease in the German Population. Gastroenterology, 136(5), A-209. doi:10.1016/s0016-5085(09)60938-0
S1194 Functional Toll-Like Receptor 5 Gene Variants Are Not Associated with Susceptibility to Inflammatory Bowel Disease in the German Population
Seiderer, J., Glas, J., Török, H. -P., Göke, B., Ochsenkühn, T., Folwaczny, M., . . . Brand, S. (2009). S1194 Functional Toll-Like Receptor 5 Gene Variants Are Not Associated with Susceptibility to Inflammatory Bowel Disease in the German Population. Gastroenterology, 136(5). doi:10.1016/s0016-5085(09)60944-6
S1198 Osteopontin (OPN/SSP1) Gene Variants in Inflammatory Bowel Disease
Seiderer, J., Glas, J., Török, H. -P., Diegelmann, J., Göke, B., Ochsenkühn, T., . . . Brand, S. (2009). S1198 Osteopontin (OPN/SSP1) Gene Variants in Inflammatory Bowel Disease. Gastroenterology, 136(5), A-211. doi:10.1016/s0016-5085(09)60947-1
A hypomorphic vasopressin allele prevents anxiety-related behavior.
Bunck, M., Czibere, L., Horvath, C., Graf, C., Frank, E., Kessler, M. S., . . . Landgraf, R. (2009). A hypomorphic vasopressin allele prevents anxiety-related behavior.. PloS one, 4(4), e5129. doi:10.1371/journal.pone.0005129
Common variants at ten loci modulate the QT interval duration in the QTSCD Study.
Pfeufer, A., Sanna, S., Arking, D. E., Müller, M., Gateva, V., Fuchsberger, C., . . . Chakravarti, A. (2009). Common variants at ten loci modulate the QT interval duration in the QTSCD Study.. Nature genetics, 41(4), 407-414. doi:10.1038/ng.362
Further evidence for DYX1C1 as a susceptibility factor for dyslexia.
Dahdouh, F., Anthoni, H., Tapia-Páez, I., Peyrard-Janvid, M., Schulte-Körne, G., Warnke, A., . . . Zucchelli, M. (2009). Further evidence for DYX1C1 as a susceptibility factor for dyslexia.. Psychiatric genetics, 19(2), 59-63. doi:10.1097/ypg.0b013e32832080e1
Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations.
Freilinger, T., Bevan, S., Ripke, S., Gschwendtner, A., Lichtner, P., Müller-Myhsok, B., . . . Dichgans, M. (2009). Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations.. Stroke, 40(3), 970-972. doi:10.1161/strokeaha.107.510800
rs224136 on Chromosome 10q21.1 and Variants in PHOX2B, NCF4, and FAM92B Are Not Major Genetic Risk Factors for Susceptibility to Crohnʼs Disease in the German Population
Glas, J., Seiderer, J., Pasciuto, G., Tillack, C., Diegelmann, J., Pfennig, S., . . . Brand, S. (2009). rs224136 on Chromosome 10q21.1 and Variants in PHOX2B, NCF4, and FAM92B Are Not Major Genetic Risk Factors for Susceptibility to Crohnʼs Disease in the German Population. American Journal of Gastroenterology, 104(3), 665-672. doi:10.14309/00000434-200903000-00026
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.
Glas, J., Seiderer, J., Pasciuto, G., Tillack, C., Diegelmann, J., Pfennig, S., . . . Brand, S. (2009). rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.. The American journal of gastroenterology, 104(3), 665-672. doi:10.1038/ajg.2008.65
P216 - The first two Crohn's disease susceptibility loci with a high degree of epistasis: PTGER4-expression-modulating polymorphisms in the 5p13.1 region enhance ATG16L1-associated susceptibility to Crohn's disease
Seiderer, J., Glas, J., Diegelmann, J., Pasciuto, G., Tillack, C., Roeske, D., . . . Brand, S. (2009). P216 - The first two Crohn's disease susceptibility loci with a high degree of epistasis: PTGER4-expression-modulating polymorphisms in the 5p13.1 region enhance ATG16L1-associated susceptibility to Crohn's disease. Journal of Crohn's and Colitis, 3(1), S96. doi:10.1016/s1873-9946(09)60243-9
P220 - The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery
Seiderer, J., Glas, J., Diegelmann, J., Pasciuto, G., Tillack, C., Pfennig, S., . . . Brand, S. (2009). P220 - The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery. Journal of Crohn's and Colitis, 3(1), S97. doi:10.1016/s1873-9946(09)60247-6
P230 - Ethnic differences in the genetic susceptibility to Crohn's disease: functional PPARγ gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Seiderer, J., Glas, J., Diegelmann, J., Markus, C., Pfennig, S., Tillack, C., . . . Brand, S. (2009). P230 - Ethnic differences in the genetic susceptibility to Crohn's disease: functional PPARγ gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Journal of Crohn's and Colitis, 3(1), S101. doi:10.1016/s1873-9946(09)60257-9
P238 - Functional Toll-like receptor 5 gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Seiderer, J., Glas, J., Diegelmann, J., Sandner, B., Pfennig, S., Török, H., . . . Brand, S. (2009). P238 - Functional Toll-like receptor 5 gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Journal of Crohn's and Colitis, 3(1), S105. doi:10.1016/s1873-9946(09)60265-8
P253 - The role of pregnane X receptor (PXR/NR1I2) gene variants in inflammatory bowel disease
Seiderer, J., Glas, J., Diegelmann, J., Fischer, D., Seitz, B., Pfennig, S., . . . Brand, S. (2009). P253 - The role of pregnane X receptor (PXR/NR1I2) gene variants in inflammatory bowel disease. Journal of Crohn's and Colitis, 3(1), S111. doi:10.1016/s1873-9946(09)60280-4
Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients.
Heck, A., Lieb, R., Ellgas, A., Pfister, H., Lucae, S., Erhardt, A., . . . Ising, M. (2009). Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 150B(1), 104-114. doi:10.1002/ajmg.b.30784
A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany.
Hoffmann, K., Planitz, C., Rüschendorf, F., Müller-Myhsok, B., Stassen, H. H., Lucke, B., . . . Lindner, T. H. (2009). A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany.. Journal of hypertension, 27(5), 983-990. doi:10.1097/hjh.0b013e328328123d
Mouse to human comparative genetics reveals a novel immunoglobulin E-controlling locus on Hsa8q12.
Gusareva, E. S., Havelková, H., Blazková, H., Kosarová, M., Kucera, P., Král, V., . . . Lipoldová, M. (2009). Mouse to human comparative genetics reveals a novel immunoglobulin E-controlling locus on Hsa8q12.. Immunogenetics, 61(1), 15-25. doi:10.1007/s00251-008-0343-x
Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.
Gschwendtner, A., Bevan, S., Cole, J. W., Plourde, A., Matarin, M., Ross-Adams, H., . . . International Stroke Genetics Consortium. (2009). Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.. Annals of neurology, 65(5), 531-539. doi:10.1002/ana.21590
2008
Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample.
Ludwig, K. U., Schumacher, J., Schulte-Körne, G., König, I. R., Warnke, A., Plume, E., . . . Hoffmann, P. (2008). Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample.. Psychiatric genetics, 18(6), 310-312. doi:10.1097/ypg.0b013e3283063a78
Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample.
Ludwig, K. U., Roeske, D., Schumacher, J., Schulte-Körne, G., König, I. R., Warnke, A., . . . Hoffmann, P. (2008). Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample.. Journal of neural transmission (Vienna, Austria : 1996), 115(11), 1587-1589. doi:10.1007/s00702-008-0124-6
Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.
Keck, M. E., Kern, N., Erhardt, A., Unschuld, P. G., Ising, M., Salyakina, D., . . . Binder, E. B. (2008). Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B(7), 1196-1204. doi:10.1002/ajmg.b.30750
Analysis of pregnane X receptor (PXR/NR1I2) gene variants in inflammatory bowel disease
Seiderer, J., Glas, J., Diegelmann, J., Tillack, C., Pfennig, S., Jürgens, M., . . . Brand, S. (n.d.). Analysis of pregnane X receptor (PXR/NR1I2) gene variants in inflammatory bowel disease. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089410
Epistasis between Toll-like receptor (TLR)-9 polymorphisms and variants in IL23R and DLG5 modulates susceptibility to Crohn's disease
Török, H. P., Glas, J., Konnerth, J., Wetzke, M., Lohse, P., Ochsenkühn, T., . . . Brand, S. (n.d.). Epistasis between Toll-like receptor (TLR)-9 polymorphisms and variants in IL23R and DLG5 modulates susceptibility to Crohn's disease. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089588
First evidence for strong epistasis between two Crohn's disease susceptibility loci: PTGER4-expression-modulating polymorphisms in the 5p13.1 region enhance ATG16L1-associated susceptibility to Crohn's disease
Seiderer, J., Glas, J., Pasciuto, G., Diegelmann, J., Tillack, C., Pfennig, S., . . . Brand, S. (n.d.). First evidence for strong epistasis between two Crohn's disease susceptibility loci: PTGER4-expression-modulating polymorphisms in the 5p13.1 region enhance ATG16L1-associated susceptibility to Crohn's disease. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089398
Functional Toll-like receptor 5 gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Glas, J., Seiderer, J., Sandner, B., Paschos, E., Tillack, C., Diegelmann, J., . . . Brand, S. (n.d.). Functional Toll-like receptor 5 gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089417
Novel protective markers for ulcerative colitis in the IL2/IL21 region suggest a common genetic background for ulcerative colitis and celiac disease
Glas, J., Wetzke, M., Roeske, D., Pfennig, S., Klein, W., Epplen, J. T., . . . Brand, S. (n.d.). Novel protective markers for ulcerative colitis in the IL2/IL21 region suggest a common genetic background for ulcerative colitis and celiac disease. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089415
The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery
Seiderer, J., Glas, J., Diegelmann, J., Pasciuto, G., Tillack, C., Pfennig, S., . . . Brand, S. (n.d.). The NOD2 variants rs2066843 and rs2076756 are novel independent Crohn's disease susceptibility gene variants associated with severe penetrating disease phenotype resulting in frequent need for surgery. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089401
The disease susceptibility risk mediated by gene variants in PHOX2B, NCF4, FAM92B, and in the intergenic region on chromosome 10q21.1 differs between North American and European patients with Crohn's disease
Diegelmann, J., Glas, J., Seiderer, J., Pasciuto, G., Tillack, C., Konrad, A., . . . Brand, S. (n.d.). The disease susceptibility risk mediated by gene variants in PHOX2B, NCF4, FAM92B, and in the intergenic region on chromosome 10q21.1 differs between North American and European patients with Crohn's disease. Zeitschrift für Gastroenterologie, 46(09). doi:10.1055/s-0028-1089404
Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism.
Heck, A., Lieb, R., Unschuld, P. G., Ellgas, A., Pfister, H., Lucae, S., . . . Ising, M. (2008). Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism.. Molecular psychiatry, 13(9), 831-832. doi:10.1038/mp.2008.2
The role of MEIS1, BTBD9 and MAP2K5/LBXCOR1 in uraemic RLS – a case-control study in patients with end stage renal disease on maintenance hemodialysis
Plag, J., Schormair, B., Samtleben, W., Müller-Myhsok, B., Illig, T., Meitinger, T., & Winkelmann, J. (2008). The role of MEIS1, BTBD9 and MAP2K5/LBXCOR1 in uraemic RLS – a case-control study in patients with end stage renal disease on maintenance hemodialysis. Aktuelle Neurologie, 35(S 01). doi:10.1055/s-0028-1086645
P.1.a.021 Association of GRIK4 and HTR2A genes with antidepressant treatment in the MARS cohort of depressed inpatients
Horstmann, S., Lucae, S., Menke, A., Ising, M., Müller-Myhsok, B., Holsboer, F., & Binder, E. (2008). P.1.a.021 Association of GRIK4 and HTR2A genes with antidepressant treatment in the MARS cohort of depressed inpatients. European Neuropsychopharmacology, 18, S214-S215. doi:10.1016/s0924-977x(08)70255-4
P.2.a.007 Variations in tryptophan hydroxylase 2 are associated with elevated risk for metabolic syndrome in depression
Kloiber, S., Kohli, M. A., Brueckl, T., Ising, M., Uhr, M., Menke, A., . . . Lucae, S. (2008). P.2.a.007 Variations in tryptophan hydroxylase 2 are associated with elevated risk for metabolic syndrome in depression. European Neuropsychopharmacology, 18, S296. doi:10.1016/s0924-977x(08)70396-1
Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation.
Menke, A., Lucae, S., Kloiber, S., Horstmann, S., Bettecken, T., Uhr, M., . . . Binder, E. B. (2008). Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation.. The American journal of psychiatry, 165(7), 917-918. doi:10.1176/appi.ajp.2008.08020274
Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker.
Glas, J., Beynon, V., Bachstein, B., Steckenbiller, J., Manolis, V., Euba, A., . . . Folwaczny, M. (2008). Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker.. Tissue antigens, 72(1), 21-28. doi:10.1111/j.1399-0039.2008.01056.x
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.
Ising, M., Depping, A. -M., Siebertz, A., Lucae, S., Unschuld, P. G., Kloiber, S., . . . Holsboer, F. (2008). Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.. The European journal of neuroscience, 28(2), 389-398. doi:10.1111/j.1460-9568.2008.06332.x
Refining genetic associations in multiple sclerosis.
International Multiple Sclerosis Genetics Consortium (IMSGC). (2008). Refining genetic associations in multiple sclerosis.. The Lancet. Neurology, 7(7), 567-569. doi:10.1016/s1474-4422(08)70122-4
Further evidence for a susceptibility locus contributing to reading disability on chromosome 15q15-q21.
Schumacher, J., König, I. R., Schröder, T., Duell, M., Plume, E., Propping, P., . . . Nöthen, M. M. (2008). Further evidence for a susceptibility locus contributing to reading disability on chromosome 15q15-q21.. Psychiatric genetics, 18(3), 137-142. doi:10.1097/ypg.0b013e3282fb7fc6
Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans.
Gschwendtner, A., Ripke, S., Freilinger, T., Lichtner, P., Müller-Myhsok, B., Wichmann, H. -E., . . . Dichgans, M. (2008). Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans.. Stroke, 39(5), 1593-1596. doi:10.1161/strokeaha.107.502179
Expansion of the phenotypic spectrum of the CACNA1A T666M mutation: a family with familial hemiplegic migraine type 1, cerebellar atrophy and mental retardation.
Freilinger, T., Bohe, M., Wegener, B., Müller-Myhsok, B., Dichgans, M., & Knoblauch, H. (2008). Expansion of the phenotypic spectrum of the CACNA1A T666M mutation: a family with familial hemiplegic migraine type 1, cerebellar atrophy and mental retardation.. Cephalalgia : an international journal of headache, 28(4), 403-407. doi:10.1111/j.1468-2982.2008.01540.x
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease.
Seiderer, J., Dambacher, J., Leistner, D., Tillack, C., Glas, J., Niess, J. -H., . . . Brand, S. (2008). Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease.. Clinical immunology (Orlando, Fla.), 127(1), 49-55. doi:10.1016/j.clim.2007.11.016
M2041 The First Two Crohn's Disease Susceptibility Loci with a High Degree of Epistasis: PTGER4-Expression-Modulating Polymorphisms in the 5p13.1 Region Enhance ATG16L1-Associated Susceptibility to Crohn's Disease
Seiderer, J., Glas, J., Diegelmann, J., Pasciuto, G., Tillack, C., Pfennig, S., . . . Brand, S. (2008). M2041 The First Two Crohn's Disease Susceptibility Loci with a High Degree of Epistasis: PTGER4-Expression-Modulating Polymorphisms in the 5p13.1 Region Enhance ATG16L1-Associated Susceptibility to Crohn's Disease. Gastroenterology, 134(4), A-456. doi:10.1016/s0016-5085(08)62134-4
M2042 The Role of Pregnane X Receptor (PXR/NR1i2) Gene Variants in Inflammatory Bowel Disease
Seiderer, J., Glas, J., Diegelmann, J., Fischer, D., Seitz, B., Tillack, C., . . . Brand, S. (2008). M2042 The Role of Pregnane X Receptor (PXR/NR1i2) Gene Variants in Inflammatory Bowel Disease. Gastroenterology, 134(4), A-457. doi:10.1016/s0016-5085(08)62135-6
M2046 Significant Differences in the Genetic Susceptibility to Crohn's Disease Between North American and European Populations Regarding Gene Variants in Phox2b, Ncf4, Fam92b, and in the Intergenic Region On Chromosome 10q21.1
Diegelmann, J., Glas, J., Seiderer, J., Pasciuto, G., Tillack, C., Konrad, A., . . . Brand, S. (2008). M2046 Significant Differences in the Genetic Susceptibility to Crohn's Disease Between North American and European Populations Regarding Gene Variants in Phox2b, Ncf4, Fam92b, and in the Intergenic Region On Chromosome 10q21.1. Gastroenterology, 134(4), A-458. doi:10.1016/s0016-5085(08)62139-3
M2047 The CARD15 Variants Rs2066843 and Rs2076756 Are New Independent Crohn's Disease Susceptibility Genes Associated with Severe Penetrating Disease Phenotype and Frequent Need for Surgery
Diegelmann, J., Glas, J., Seiderer, J., Pasciuto, G., Tillack, C., Pfennig, S., . . . Brand, S. (2008). M2047 The CARD15 Variants Rs2066843 and Rs2076756 Are New Independent Crohn's Disease Susceptibility Genes Associated with Severe Penetrating Disease Phenotype and Frequent Need for Surgery. Gastroenterology, 134(4), A-458. doi:10.1016/s0016-5085(08)62140-x
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.
Seiderer, J., Elben, I., Diegelmann, J., Glas, J., Stallhofer, J., Tillack, C., . . . Brand, S. (2008). Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.. Inflammatory bowel diseases, 14(4), 437-445. doi:10.1002/ibd.20339
Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks.
Erhardt, A., Lucae, S., Kern, N., Unschuld, P. G., Ising, M., Lieb, R., . . . Holsboer, F. (2008). Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks.. Molecular psychiatry, 13(3), 242-243. doi:10.1038/sj.mp.4002094
P.3.10 Glutamate and interleukin receptor genes are associated with antidepressant treatment emergent suicidal ideation
Menke, A., Lucae, S., Kloiber, S., Horstmann, S., Uhr, M., Pütz, B., . . . Holsboer, F. (2008). P.3.10 Glutamate and interleukin receptor genes are associated with antidepressant treatment emergent suicidal ideation. European Neuropsychopharmacology, 18, s70-s71. doi:10.1016/s0924-977x(08)70081-6
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.
Glas, J., Konrad, A., Schmechel, S., Dambacher, J., Seiderer, J., Schroff, F., . . . Brand, S. (2008). The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.. The American journal of gastroenterology, 103(3), 682-691. doi:10.1111/j.1572-0241.2007.01694.x
Genetics of restless legs syndrome: a burning urge to move.
Winkelmann, J., & Müller-Myhsok, B. (2008). Genetics of restless legs syndrome: a burning urge to move.. Neurology, 70(9), 664-665. doi:10.1212/01.wnl.0000302178.53759.92
Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome.
Winkelmann, J., Lichtner, P., Schormair, B., Uhr, M., Hauk, S., Stiasny-Kolster, K., . . . Müller-Myhsok, B. (2008). Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome.. Movement disorders : official journal of the Movement Disorder Society, 23(3), 350-358. doi:10.1002/mds.21647
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.
Uhr, M., Tontsch, A., Namendorf, C., Ripke, S., Lucae, S., Ising, M., . . . Holsboer, F. (2008). Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.. Neuron, 57(2), 203-209. doi:10.1016/j.neuron.2007.11.017
Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.
Browning, B. L., Annese, V., Barclay, M. L., Bingham, S. A., Brand, S., Büning, C., . . . Witt, H. (2008). Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.. Journal of medical genetics, 45(1), 36-42. doi:10.1136/jmg.2007.050773
IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.
Weber, F., Fontaine, B., Cournu-Rebeix, I., Kroner, A., Knop, M., Lutz, S., . . . Müller-Myhsok, B. (2008). IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.. Genes and immunity, 9(3), 259-263. doi:10.1038/gene.2008.14
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.
Schormair, B., Kemlink, D., Roeske, D., Eckstein, G., Xiong, L., Lichtner, P., . . . Winkelmann, J. (2008). PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.. Nature genetics, 40(8), 946-948. doi:10.1038/ng.190
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder.
Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Kohli, M., Kloiber, S., . . . Keck, M. E. (2008). Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder.. Journal of affective disorders, 105(1-3), 177-184. doi:10.1016/j.jad.2007.05.006
2007
Mutation Rate
Müller‐Myhsok, B. (n.d.). Mutation Rate. Wiley. doi:10.1002/9780470015902.a0005441.pub2
Genetics and Neuroscience in Dyslexia: Perspectives for Education and Remediation
Schulte‐Körne, G., Ludwig, K. U., El Sharkawy, J., Nöthen, M. M., Müller‐Myhsok, B., & Hoffmann, P. (2007). Genetics and Neuroscience in Dyslexia: Perspectives for Education and Remediation. Mind, Brain, and Education, 1(4), 162-172. doi:10.1111/j.1751-228x.2007.00017.x
Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.
Thoeringer, C. K., Binder, E. B., Salyakina, D., Erhardt, A., Ising, M., Unschuld, P. G., . . . Keck, M. E. (2007). Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.. Journal of psychiatric research, 41(7), 579-584. doi:10.1016/j.jpsychires.2006.06.001
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.
Glas, J., Seiderer, J., Wetzke, M., Konrad, A., Török, H. -P., Schmechel, S., . . . Brand, S. (2007). rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.. PloS one, 2(9), e819. doi:10.1371/journal.pone.0000819
A genome-wide association study in patients with panic and anxiety disorders
Erhardt, A., Unschuld, P. G., Ripke, S., Lucae, S., Kohli, M., Kloiber, S., . . . Holsboer, F. (2007). A genome-wide association study in patients with panic and anxiety disorders. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991797
Polymorphisms in the Leptin Gene are Associated with Resistance to Antidepressant Treatment and Lower Cognitive Performance in Depression
Kloiber, S., Ripke, S., Kohli, M., Reppermund, S., Salyakina, D., Bettecken, T., . . . Lucae, S. (2007). Polymorphisms in the Leptin Gene are Associated with Resistance to Antidepressant Treatment and Lower Cognitive Performance in Depression. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991701
Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
Heck, A., Lieb, R., Ellgas, A., Pfister, H., Lucae, S., Erhardt, A., . . . Ising, M. (2007). Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991694
Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
Heck, A., Lieb, R., Ellgas, A., Pfister, H., Lucae, S., Erhardt, A., . . . Ising, M. (2007). Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991693
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder
Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Kohli, M., Kloiber, S., . . . Keck, M. E. (2007). Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991733
SNPs in the NTRK2 gene are associated with age-at-onset of depressive disorder and attempted suicide
Kohli, M. A., Salyakina, D., Binder, E. B., Lucae, S., Ising, M., Ripke, S., . . . Müller-Myhsok, B. (2007). SNPs in the NTRK2 gene are associated with age-at-onset of depressive disorder and attempted suicide. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991706
SNPs in the NTRK2 gene are associated with depressive disorder
Kohli, M. A., Salyakina, D., Binder, E. B., Lucae, S., Ising, M., Ripke, S., . . . Müller-Myhsok, B. (2007). SNPs in the NTRK2 gene are associated with depressive disorder. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991707
Susceptibility gene hunting for recurrent unipolar depression using 400k genome-wide genotype data
Kohli, M. A., Salyakina, D., Lucae, S., Ising, M., Bettecken, T., Ripke, S., . . . Müller-Myhsok, B. (2007). Susceptibility gene hunting for recurrent unipolar depression using 400k genome-wide genotype data. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991708
Whole genome analysis reveals new potential drug targets as predictors of antidepressant treatment response
Lucae, S., Marcus, I., Saemann, P., Bettecken, T., Uhr, M., Ripke, S., . . . Müller-Myhsok, B. (2007). Whole genome analysis reveals new potential drug targets as predictors of antidepressant treatment response. Pharmacopsychiatry, 40(05). doi:10.1055/s-2007-991712
Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.
Erhardt, A., Lucae, S., Unschuld, P. G., Ising, M., Kern, N., Salyakina, D., . . . Holsboer, F. (2007). Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.. Journal of affective disorders, 101(1-3), 159-168. doi:10.1016/j.jad.2006.11.016
IL23R variants are associated with inflammatory bowel disease in the German population
Glas, J., Seiderer, J., Wetzke, M., Konrad, A., Török, H. P., Schmechel, S., . . . Brand, S. (2007). IL23R variants are associated with inflammatory bowel disease in the German population. Zeitschrift für Gastroenterologie, 45(08). doi:10.1055/s-2007-988358
Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease.
Rosenberger, A., Sharma, M., Müller-Myhsok, B., Gasser, T., & Bickeböller, H. (2007). Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease.. BMC genetics, 8, 44. doi:10.1186/1471-2156-8-44
Talking hypotheses
Müller-Myhsok, B. (2007). Talking hypotheses. European Journal of Human Genetics, 15(7), 817. doi:10.1038/sj.ejhg.5201853
Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.
Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Kloiber, S., Kohli, M., . . . Keck, M. E. (2007). Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 144B(4), 424-429. doi:10.1002/ajmg.b.30412
A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.
Anthoni, H., Zucchelli, M., Matsson, H., Müller-Myhsok, B., Fransson, I., Schumacher, J., . . . Peyrard-Janvid, M. (2007). A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.. Human molecular genetics, 16(6), 667-677. doi:10.1093/hmg/ddm009
Assoziation zwischen Herzerkrankungen und Depressionen
Baghai, T. C., Binder, E., Schüle, C., Lucae, S., Eser, D., Müller‐Myhsok, B., . . . Bondy, B. (2007). Assoziation zwischen Herzerkrankungen und Depressionen. Biologie in unserer Zeit, 37(5), 284-286. doi:10.1002/biuz.200790076
Genetic variation in the lymphotoxin alpha pathway and the risk of ischaemic stroke
Dichgans, M., Gschwendtner, A., Bevan, S., Lichtner, P., Ripke, S., Müller-Myhsok, B., . . . Freilinger, T. (2007). Genetic variation in the lymphotoxin alpha pathway and the risk of ischaemic stroke. Aktuelle Neurologie, 34(S 2). doi:10.1055/s-2007-987789
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.
Winkelmann, J., Schormair, B., Lichtner, P., Ripke, S., Xiong, L., Jalilzadeh, S., . . . Meitinger, T. (2007). Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.. Nature genetics, 39(8), 1000-1006. doi:10.1038/ng2099
Sequence variation in the gene encoding soluble epoxide hydrolase (EPHX2) is associated with increased susceptibility to ischemic stroke in a central european population
Gschwendtner, A., Ripke, S., Freilinger, T., Müller-Myhsok, B., Meitinger, T., & Dichgans, M. (2007). Sequence variation in the gene encoding soluble epoxide hydrolase (EPHX2) is associated with increased susceptibility to ischemic stroke in a central european population. Aktuelle Neurologie, 34(S 2). doi:10.1055/s-2007-987777
2006
Genes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity.
Graefe, S. E. B., Streichert, T., Budde, B. S., Nürnberg, P., Steeg, C., Müller-Myhsok, B., & Fleischer, B. (2006). Genes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity.. PloS one, 1, e57. doi:10.1371/journal.pone.0000057
Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers.
Opherk, C., Peters, N., Holtmannspötter, M., Gschwendtner, A., Müller-Myhsok, B., & Dichgans, M. (2006). Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers.. Stroke, 37(11), 2684-2689. doi:10.1161/01.str.0000245084.35575.66
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.
Baghai, T. C., Binder, E. B., Schule, C., Salyakina, D., Eser, D., Lucae, S., . . . Bondy, B. (2006). Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.. Molecular psychiatry, 11(11), 1003-1015. doi:10.1038/sj.mp.4001884
Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial.
Bender, A., Koch, W., Elstner, M., Schombacher, Y., Bender, J., Moeschl, M., . . . Klopstock, T. (2006). Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial.. Neurology, 67(7), 1262-1264. doi:10.1212/01.wnl.0000238518.34389.12
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.
Lucae, S., Salyakina, D., Barden, N., Harvey, M., Gagné, B., Labbé, M., . . . Müller-Myhsok, B. (2006). P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.. Human molecular genetics, 15(16), 2438-2445. doi:10.1093/hmg/ddl166
RLS3: fine-mapping of an autosomal dominant locus in a family with intrafamilial heterogeneity.
Liebetanz, K. M., Winkelmann, J., Trenkwalder, C., Pütz, B., Dichgans, M., Gasser, T., & Müller-Myhsok, B. (2006). RLS3: fine-mapping of an autosomal dominant locus in a family with intrafamilial heterogeneity.. Neurology, 67(2), 320-321. doi:10.1212/01.wnl.0000224886.65213.b5
Genetic Risk: Computation
Grimm, T., & Müller‐Myhsok, B. (n.d.). Genetic Risk: Computation. Wiley. doi:10.1038/npg.els.0005433
Mutation Rate
Müller‐Myhsok, B. (n.d.). Mutation Rate. Wiley. doi:10.1038/npg.els.0005441
The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations.
Sharma, M., Mueller, J. C., Zimprich, A., Lichtner, P., Hofer, A., Leitner, P., . . . European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD). (2006). The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations.. Journal of medical genetics, 43(7), 557-562. doi:10.1136/jmg.2005.039149
Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder.
Barden, N., Harvey, M., Gagné, B., Shink, E., Tremblay, M., Raymond, C., . . . Müller-Myhsok, B. (2006). Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 141B(4), 374-382. doi:10.1002/ajmg.b.30303
Chromosome 6
Müller‐Myhsok, B., & Ziegler, A. (n.d.). Chromosome 6. Wiley. doi:10.1038/npg.els.0005815
Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome.
Winkelmann, J., Lichtner, P., Pütz, B., Trenkwalder, C., Hauk, S., Meitinger, T., . . . Muller-Myhsok, B. (2006). Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome.. Movement disorders : official journal of the Movement Disorder Society, 21(1), 28-33. doi:10.1002/mds.20627
Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers
Opherk, C., Peters, N., Holtmannspötter, M., Gschwendtner, A., Müller-Myhsok, B., & Dichgans, M. (2006). Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers. Aktuelle Neurologie, 33(S 1). doi:10.1055/s-2006-953281
Linkage analysis and relatedness of maternal lines of type 1 diabetes patients: significant linkage to markers on chromosome 6, 11 and 14
Klöting, N., Müller-Myhsok, B., Rjasanowski, I., Kerner, W., & Klöting, I. (2006). Linkage analysis and relatedness of maternal lines of type 1 diabetes patients: significant linkage to markers on chromosome 6, 11 and 14. Diabetologie und Stoffwechsel, 1(S 1). doi:10.1055/s-2006-943730
New loci for restless legs syndrome map to chromosome 4q and 17p
Winkelmann, J., Lichtner, P., Kemlink, D., Polo, O., Montagna, P., Högl, B., . . . Müller-Myhsok, B. (2006). New loci for restless legs syndrome map to chromosome 4q and 17p. Aktuelle Neurologie, 33(S 1). doi:10.1055/s-2006-952980
Possible genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders
Erhardt, A., Unschuld, P. G., Lucae, S., Ising, M., Salyakina, D., Pütz, B., . . . Keck, M. E. (2006). Possible genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders. European Neuropsychopharmacology, 16, S88. doi:10.1016/s0924-977x(06)80104-5
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes.
Glas, J., Török, H. -P., Tonenchi, L., Müller-Myhsok, B., Mussack, T., Wetzke, M., . . . Folwaczny, C. (2006). Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes.. Inflammatory bowel diseases, 12(7), 606-611. doi:10.1097/01.ibd.0000225346.23765.6b
SNPs in FKBP5 determine a novel subtype of depression characterized by rapid response to antidepressant treatment
Binder, E. B., Lucae, S., Salyakina, D., Lichtner, P., Meitinger, T., Bondy, B., . . . Müller-Myhsok, B. (2006). SNPs in FKBP5 determine a novel subtype of depression characterized by rapid response to antidepressant treatment. European Neuropsychopharmacology, 16, S75. doi:10.1016/s0924-977x(06)80089-1
2005
Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.
Glas, J., Török, H. -P., Tonenchi, L., Kapser, J., Schiemann, U., Müller-Myhsok, B., . . . Folwaczny, C. (2005). Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.. Inflammatory bowel diseases, 11(12), 1031-1037. doi:10.1097/01.mib.0000187574.41290.b1
SimPed: a simulation program to generate haplotype and genotype data for pedigree structures.
Leal, S. M., Yan, K., & Müller-Myhsok, B. (2005). SimPed: a simulation program to generate haplotype and genotype data for pedigree structures.. Human heredity, 60(2), 119-122. doi:10.1159/000088914
A new locus for restless legs syndrome maps to chromosome 4q
Winkelmann, J., Lichtner, P., Puetz, B., Hauk, S., Trenkwalder, C., Strom, T., . . . Müller-Myhsok, B. (n.d.). A new locus for restless legs syndrome maps to chromosome 4q. Aktuelle Neurologie, 32(S 4). doi:10.1055/s-2005-919219
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.
Török, H. -P., Glas, J., Tonenchi, L., Lohse, P., Müller-Myhsok, B., Limbersky, O., . . . Folwaczny, C. (2005). Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.. Gut, 54(10), 1421-1427. doi:10.1136/gut.2005.066340
Evaluation of Nyholt's procedure for multiple testing correction.
Salyakina, D., Seaman, S. R., Browning, B. L., Dudbridge, F., & Muller-Myhsok, B. (2005). Evaluation of Nyholt's procedure for multiple testing correction.. Human heredity, 60(1), 19-25. doi:10.1159/000087540
GABA transporter1 (GAT1) inhibition mediates distinct emotional and cognitive processes and represents a possible treatment strategy compensating genetic polymorphisms in panic disorder
Thoeringer, C. K., Binder, E. B., Lucae, S., Erhardt, A., Unschuld, P. G., Harbich, D., . . . Holsboer, F. (2005). GABA transporter1 (GAT1) inhibition mediates distinct emotional and cognitive processes and represents a possible treatment strategy compensating genetic polymorphisms in panic disorder. Pharmacopsychiatry, 38(05). doi:10.1055/s-2005-918854
Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: is there any evidence for the continuum hypothesis?
Erhardt, A., Seaman, S. R., Lucae, S., Kern, N., Unschuld, P. G., Welt, T., . . . Keck, M. E. (2005). Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: is there any evidence for the continuum hypothesis?. Pharmacopsychiatry, 38(05). doi:10.1055/s-2005-918676
Polymorphisms in the serotonin receptor gene HTR2A modulate disease severity and susceptibility for anxiety disorders but not depression and are associated with specific personality traits
Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Welt, T., Kloiber, S., . . . Keck, M. E. (2005). Polymorphisms in the serotonin receptor gene HTR2A modulate disease severity and susceptibility for anxiety disorders but not depression and are associated with specific personality traits. Pharmacopsychiatry, 38(05). doi:10.1055/s-2005-918859
Reply to Lin
Seaman, S. R., & Müller-Myhsok, B. (2005). Reply to Lin. The American Journal of Human Genetics, 77(3), 514-515. doi:10.1086/432818
Within- and Inter- gene interactions in FKBP5 and GR genes and its association with early response
Salyakina, D., Binder, E. B., Ising, M., Uhr, M., Lucae, S., & Müller-Myhsok, B. (2005). Within- and Inter- gene interactions in FKBP5 and GR genes and its association with early response. Pharmacopsychiatry, 38(05). doi:10.1055/s-2005-918825
Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease.
Martinez, M., Brice, A., Vaughan, J. R., Zimprich, A., Breteler, M. M. B., Meco, G., . . . Dürr, A. (2005). Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 136B(1), 72-74. doi:10.1002/ajmg.b.30196
The usefulness of single nucleotide polymorphisms (SNPs) for genetic epidemiological investigation of complex psychiatric diseases.
Müller-Myhsok, B. (2005). The usefulness of single nucleotide polymorphisms (SNPs) for genetic epidemiological investigation of complex psychiatric diseases.. Progress in neuro-psychopharmacology & biological psychiatry, 29(6), 1017-1020. doi:10.1016/j.pnpbp.2005.03.018
Developmental dyslexia--recurrence risk estimates from a german bi-center study using the single proband sib pair design.
Ziegler, A., König, I. R., Deimel, W., Plume, E., Nöthen, M. M., Propping, P., . . . Schulte-Körne, G. (2005). Developmental dyslexia--recurrence risk estimates from a german bi-center study using the single proband sib pair design.. Human heredity, 59(3), 136-143. doi:10.1159/000085572
Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease.
Klopstock, T., Elstner, M., Lücking, C. B., Müller-Myhsok, B., Gasser, T., Botz, E., . . . Hörtnagel, K. (2005). Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease.. Neuroscience letters, 379(3), 195-198. doi:10.1016/j.neulet.2004.12.061
Epsilon-sarcoglycan is not involved in sporadic Gilles de la Tourette syndrome.
Asmus, F., Schoenian, S., Lichtner, P., Munz, M., Mayer, P., Muller-Myhsok, B., . . . Gasser, T. (2005). Epsilon-sarcoglycan is not involved in sporadic Gilles de la Tourette syndrome.. Neurogenetics, 6(1), 55-56. doi:10.1007/s10048-004-0206-z
On rapid stimulation of P values in association studies.
Lin, D. Y. (2005). On rapid stimulation of P values in association studies.. American journal of human genetics, 77(3), 513-514. doi:10.1086/432817
PARK11 is not linked with Parkinson's disease in European families.
Prestel, J., Sharma, M., Leitner, P., Zimprich, A., Vaughan, J. R., Dürr, A., . . . European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD). (2005). PARK11 is not linked with Parkinson's disease in European families.. European journal of human genetics : EJHG, 13(2), 193-197. doi:10.1038/sj.ejhg.5201317
Rapid simulation of P values for product methods and multiple-testing adjustment in association studies.
Seaman, S. R., & Müller-Myhsok, B. (2005). Rapid simulation of P values for product methods and multiple-testing adjustment in association studies.. American journal of human genetics, 76(3), 399-408. doi:10.1086/428140
2004
Relevance of ex vivo blood lymphocyte assay for in vivo lymphocyte function.
Brattig, N. W., Timmann, C., Abraha, R. S., Lepping, B., Müller-Myhsok, B., & Horstmann, R. D. (2005). Relevance of ex vivo blood lymphocyte assay for in vivo lymphocyte function.. Clinical and experimental immunology, 139(1), 127-131. doi:10.1111/j.1365-2249.2005.02667.x
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder, E. B., Salyakina, D., Lichtner, P., Wochnik, G. M., Ising, M., Pütz, B., . . . Muller-Myhsok, B. (2004). Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.. Nature genetics, 36(12), 1319-1325. doi:10.1038/ng1479
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Zimprich, A., Biskup, S., Leitner, P., Lichtner, P., Farrer, M., Lincoln, S., . . . Gasser, T. (2004). Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.. Neuron, 44(4), 601-607. doi:10.1016/j.neuron.2004.11.005
Evidence for genetic heterogeneity in Restless Legs Syndrome
Winkelmann, J., Lichtner, P., Strom, T. M., Trenkwalder, C., Meitinger, T., & Müller-Myhsok, B. (n.d.). Evidence for genetic heterogeneity in Restless Legs Syndrome. Pharmacopsychiatry, 36(05). doi:10.1055/s-2003-825558
HPA axis dysregulation and suicidal behavior in depression – Differentiation of a genetically distinct subgroup?
Pfennig, A., Kuenzel, H. E., Kern, N., Fuchs, B., Brunner, J., Ising, M., . . . Holsboer, F. (n.d.). HPA axis dysregulation and suicidal behavior in depression – Differentiation of a genetically distinct subgroup?. Pharmacopsychiatry, 36(05). doi:10.1055/s-2003-825457
Is there a genetic continuum between anxiety and depression?
Kern, N., Binder, E. B., Künzel, H. E., Pfennig, A., Fuchs, B., Ising, M., . . . Holsboer, F. (n.d.). Is there a genetic continuum between anxiety and depression?. Pharmacopsychiatry, 36(05). doi:10.1055/s-2003-825399
Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis.
Dörr, S., Lechtenböhmer, N., Rau, R., Herborn, G., Wagner, U., Müller-Myhsok, B., . . . Keyszer, G. (2004). Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis.. Arthritis research & therapy, 6(3), R199-R207. doi:10.1186/ar1164
Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen.
Timmann, C., Fuchs, S., Thoma, C., Lepping, B., Brattig, N. W., Sievertsen, J., . . . Horstmann, R. D. (2004). Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen.. Genes and immunity, 5(4), 256-260. doi:10.1038/sj.gene.6364094
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.
Wszolek, Z. K., Pfeiffer, R. F., Tsuboi, Y., Uitti, R. J., McComb, R. D., Stoessl, A. J., . . . Dickson, D. W. (2004). Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.. Neurology, 62(9), 1619-1622. doi:10.1212/01.wnl.0000125015.06989.db
A gene locus responsible for the familial hair shaft abnormality pili annulati maps to chromosome 12q24.32-24.33.
Giehl, K. A., Eckstein, G. N., Benet-Pagès, A., Tosti, A., de Berker, D. A. R., Meitinger, T., . . . Strom, T. M. (2004). A gene locus responsible for the familial hair shaft abnormality pili annulati maps to chromosome 12q24.32-24.33.. The Journal of investigative dermatology, 123(6), 1073-1077. doi:10.1111/j.0022-202x.2004.23423.x
The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.
Zimprich, A., Müller-Myhsok, B., Farrer, M., Leitner, P., Sharma, M., Hulihan, M., . . . Gasser, T. (2004). The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.. American journal of human genetics, 74(1), 11-19. doi:10.1086/380647
2003
Murine susceptibility to Chagas' disease maps to chromosomes 5 and 17.
Graefe, S. E. B., Meyer, B. S., Müller-Myhsok, B., Rüschendorf, F., Drosten, C., Laue, T., . . . Fleischer, B. (2003). Murine susceptibility to Chagas' disease maps to chromosomes 5 and 17.. Genes and immunity, 4(5), 321-325. doi:10.1038/sj.gene.6363972
Parkin mutations are frequent in patients with isolated early-onset parkinsonism.
Periquet, M., Latouche, M., Lohmann, E., Rawal, N., De Michele, G., Ricard, S., . . . European Consortium on Genetic Susceptibility in Parkinson's Disease. (2003). Parkin mutations are frequent in patients with isolated early-onset parkinsonism.. Brain : a journal of neurology, 126(Pt 6), 1271-1278. doi:10.1093/brain/awg136
Is there relatedness between maternal lines of Type 1 diabetic patients?
Klöting, I., Poetsch, M., Müller-Myhsok, B., Rjasanowski, I., Kerner, W., & Klöting, N. (2003). Is there relatedness between maternal lines of Type 1 diabetic patients?. Diabetologia, 46(3), 441-442. doi:10.1007/s00125-003-1048-1
Apolipoprotein B-100 gene mutations and cholesterol control in German patients.
Loggen, U., Boden, A., Baron, H., Schuster, H., Tolle, R., Netwich, U., . . . Luft, F. C. (2003). Apolipoprotein B-100 gene mutations and cholesterol control in German patients.. Atherosclerosis, 166(2), 411-412. doi:10.1016/s0021-9150(02)00377-5
Genomewide linkage analysis identifies polymorphism in the human interferon-gamma receptor affecting Helicobacter pylori infection.
Thye, T., Burchard, G. D., Nilius, M., Müller-Myhsok, B., & Horstmann, R. D. (2003). Genomewide linkage analysis identifies polymorphism in the human interferon-gamma receptor affecting Helicobacter pylori infection.. American journal of human genetics, 72(2), 448-453. doi:10.1086/367714
Association of human leucocyte DR and DQ antigens in Crohn's disease in Asian Indians: a family study.
Thakur, S., Ranjan, P., Ghoshal, U. C., Muller-Myhsok, B., Khan, F., Talwar, S., & Agarwal, S. (2003). Association of human leucocyte DR and DQ antigens in Crohn's disease in Asian Indians: a family study.. Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 24(4), 185-188.
Ian N.M. Day (ed) Molecular genetic epidemiology: a laboratory perspective
Ziegler, A., & Müller-Myhsok, B. (2003). Ian N.M. Day (ed) Molecular genetic epidemiology: a laboratory perspective. Human Genetics, 112(1), 101-102. doi:10.1007/s00439-002-0846-8
2002
Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age at onset families.
Winkelmann, J., Muller-Myhsok, B., Wittchen, H. -U., Hock, B., Prager, M., Pfister, H., . . . Trenkwalder, C. (2002). Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age at onset families.. Annals of neurology, 52(3), 297-302. doi:10.1002/ana.10282
The variant Arg110Gln of human IL-13 is associated with an immunologically hyper-reactive form of onchocerciasis (sowda).
Hoerauf, A., Kruse, S., Brattig, N. W., Heinzmann, A., Mueller-Myhsok, B., & Deichmann, K. A. (2002). The variant Arg110Gln of human IL-13 is associated with an immunologically hyper-reactive form of onchocerciasis (sowda).. Microbes and infection, 4(1), 37-42. doi:10.1016/s1286-4579(01)01507-6
Association and Linkage of Human Leukocyte Antigens with Psoriasis – Revisited
Eiermann, T. H., Vejbaesya, S., Prestel, H., Roepke, A., Müller-Myhsok, B., & Schmitt-Egenolf, M. (2002). Association and Linkage of Human Leukocyte Antigens with Psoriasis – Revisited. Transfusion Medicine and Hemotherapy, 29(6), 326-330. doi:10.1159/000068267
Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene.
Giess, R., Holtmann, B., Braga, M., Grimm, T., Müller-Myhsok, B., Toyka, K. V., & Sendtner, M. (2002). Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene.. American journal of human genetics, 70(5), 1277-1286. doi:10.1086/340427
Epidemiology of amebiasis in a region of high incidence of amebic liver abscess in central Vietnam.
Blessmann, J., Van Linh, P., Nu, P. A. T., Thi, H. D., Muller-Myhsok, B., Buss, H., & Tannich, E. (2002). Epidemiology of amebiasis in a region of high incidence of amebic liver abscess in central Vietnam.. The American journal of tropical medicine and hygiene, 66(5), 578-583. doi:10.4269/ajtmh.2002.66.578
2001
Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.
West, A. B., Zimprich, A., Lockhart, P. J., Farrer, M., Singleton, A., Holtom, B., . . . Gasser, T. (2001). Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.. European journal of human genetics : EJHG, 9(9), 659-666. doi:10.1038/sj.ejhg.5200698
Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus-dystonia syndrome.
Zimprich, A., Grabowski, M., Asmus, F., Naumann, M., Berg, D., Bertram, M., . . . Gasser, T. (2001). Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus-dystonia syndrome.. Nature genetics, 29(1), 66-69. doi:10.1038/ng709
Results from a genome-wide search for predisposing genes in sarcoidosis.
Schürmann, M., Reichel, P., Müller-Myhsok, B., Schlaak, M., Müller-Quernheim, J., & Schwinger, E. (2001). Results from a genome-wide search for predisposing genes in sarcoidosis.. American journal of respiratory and critical care medicine, 164(5), 840-846. doi:10.1164/ajrccm.164.5.2007056
Inherited Myoclonus-dystonia syndrome: narrowing the 7q21-q31 locus in German families.
Asmus, F., Zimprich, A., Naumann, M., Berg, D., Bertram, M., Ceballos-Baumann, A., . . . Gasser, T. (2001). Inherited Myoclonus-dystonia syndrome: narrowing the 7q21-q31 locus in German families.. Annals of neurology, 49(1), 121-124. doi:3.0.co;2-8">10.1002/1531-8249(200101)49:1<121::aid-ana20>3.0.co;2-8
Angiotensin-converting enzyme (ACE) gene polymorphisms and familial occurrence of sarcoidosis.
Schürmann, M., Reichel, P., Müller-Myhsok, B., Dieringer, T., Wurm, K., Schlaak, M., . . . Schwinger, E. (2001). Angiotensin-converting enzyme (ACE) gene polymorphisms and familial occurrence of sarcoidosis.. Journal of internal medicine, 249(1), 77-83. doi:10.1046/j.1365-2796.2001.00776.x
Origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from Founder effects.
Periquet, M., Lücking, C., Vaughan, J., Bonifati, V., Dürr, A., De Michele, G., . . . French Parkinson's Disease Genetics Study Group. The European Consortium on Genetic Susceptibility in Parkinson's Disease. (2001). Origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from Founder effects.. American journal of human genetics, 68(3), 617-626. doi:10.1086/318791
2000
A region on chromosome 3 is linked to dizygotic twinning.
Busjahn, A., Knoblauch, H., Faulhaber, H. D., Aydin, A., Uhlmann, R., Tuomilehto, J., . . . Müller-Myhsok, B. (2000). A region on chromosome 3 is linked to dizygotic twinning.. Nature genetics, 26(4), 398-399. doi:10.1038/82515
Proof of genetic heterogeneity in the proximal myotonic myopathy syndrome (PROMM) and its relationship to myotonic dystrophy type 2 (DM2).
Kress, W., Mueller-Myhsok, B., Ricker, K., Schneider, C., Koch, M. C., Toyka, K. V., . . . Grimm, T. (2000). Proof of genetic heterogeneity in the proximal myotonic myopathy syndrome (PROMM) and its relationship to myotonic dystrophy type 2 (DM2).. Neuromuscular disorders : NMD, 10(7), 478-480. doi:10.1016/s0960-8966(00)00129-2
Familial sarcoidosis is linked to the major histocompatibility complex region.
Schürmann, M., Lympany, P. A., Reichel, P., Müller-Myhsok, B., Wurm, K., Schlaak, M., . . . Schwinger, E. (2000). Familial sarcoidosis is linked to the major histocompatibility complex region.. American journal of respiratory and critical care medicine, 162(3 Pt 1), 861-864. doi:10.1164/ajrccm.162.3.9901099
A Cholesterol-lowering gene maps to chromosome 13Q
Knoblauch, H., Müller-Myhsok, B., Busjahn, A., Ben Avi, L., Schuster, H., Luft, F. C., & Leftersdorf, E. (2000). A Cholesterol-lowering gene maps to chromosome 13Q. Atherosclerosis, 151(1), 236. doi:10.1016/s0021-9150(00)81067-9
Support for linkage of familial combined hyperlipidemia to chromosome 1q21-q23 in Chinese and German families.
Pei, W., Baron, H., Müller-Myhsok, B., Knoblauch, H., Al-Yahyaee, S. A., Hui, R., . . . Schuster, H. (2000). Support for linkage of familial combined hyperlipidemia to chromosome 1q21-q23 in Chinese and German families.. Clinical genetics, 57(1), 29-34. doi:10.1034/j.1399-0004.2000.570105.x
A cholesterol-lowering gene maps to chromosome 13q.
Knoblauch, H., Müller-Myhsok, B., Busjahn, A., Ben Avi, L., Bähring, S., Baron, H., . . . Leitersdorf, E. (2000). A cholesterol-lowering gene maps to chromosome 13q.. American journal of human genetics, 66(1), 157-166. doi:10.1086/302704
Association of human leucocyte-DR and DQ antigens in coeliac disease: a family study.
Agrawal, S., Gupta, A., Yachha, S. K., Müller-Myhsok, B., Mehrotra, P., & Agarwal, S. S. (2000). Association of human leucocyte-DR and DQ antigens in coeliac disease: a family study.. Journal of gastroenterology and hepatology, 15(7), 771-774. doi:10.1046/j.1440-1746.2000.02227.x
CD4 alphabeta T lymphocytes express high levels of the T lymphocyte antigen CTLA-4 (CD152) in acute malaria.
Schlotmann, T., Waase, I., Jülch, C., Klauenberg, U., Müller-Myhsok, B., Dietrich, M., . . . Bröker, B. M. (2000). CD4 alphabeta T lymphocytes express high levels of the T lymphocyte antigen CTLA-4 (CD152) in acute malaria.. The Journal of infectious diseases, 182(1), 367-370. doi:10.1086/315690
[Linkage of familial combined hyperlipidemia to chromosome 1q21-23 in Chinese and German families].
Pei, W., Baron, H., & Müller-Myhsok, B. (2000). [Linkage of familial combined hyperlipidemia to chromosome 1q21-23 in Chinese and German families].. Zhonghua yi xue za zhi, 80(1), 25-27.
1999
Testing for linkage of eye tracking dysfunction and schizophrenia to markers on chromosomes 6, 8, 9, 20, and 22 in families multiply affected with schizophrenia.
Arolt, V., Lencer, R., Purmann, S., Schürmann, M., Müller-Myhsok, B., Krecker, K., & Schwinger, E. (1999). Testing for linkage of eye tracking dysfunction and schizophrenia to markers on chromosomes 6, 8, 9, 20, and 22 in families multiply affected with schizophrenia.. American journal of medical genetics, 88(6), 603-606. doi:3.0.co;2-x">10.1002/(sici)1096-8628(19991215)88:6<603::aid-ajmg5>3.0.co;2-x
A new mutation in the elastin gene causing supravalvular aortic stenosis.
Boeckel, T., Dierks, A., Vergopoulos, A., Bähring, S., Knoblauch, H., Müller-Myhsok, B., . . . Schuster, H. (1999). A new mutation in the elastin gene causing supravalvular aortic stenosis.. The American journal of cardiology, 83(7), 1141-10. doi:10.1016/s0002-9149(99)00032-6
Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15.
Nöthen, M. M., Schulte-Körne, G., Grimm, T., Cichon, S., Vogt, I. R., Müller-Myhsok, B., . . . Remschmidt, H. (1999). Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15.. European child & adolescent psychiatry, 8 Suppl 3, 56-59. doi:10.1007/pl00010696
Linkage analysis and genetic models in dyslexia--considerations pertaining to discrete trait analysis and quantitative trait analyses.
Müller-Myhsok, B., & Grimm, T. (1999). Linkage analysis and genetic models in dyslexia--considerations pertaining to discrete trait analysis and quantitative trait analyses.. European child & adolescent psychiatry, 8 Suppl 3, 40-42. doi:10.1007/pl00010692
Linkage disequilibrium and haplotype analysis in German Friedreich ataxia families.
Zühlke, C., Gehlken, U., Purmann, S., Kunisch, M., Müller-Myhsok, B., Kreuz, F., & Laccone, F. (1999). Linkage disequilibrium and haplotype analysis in German Friedreich ataxia families.. Human heredity, 49(2), 90-96. doi:10.1159/000022851
Linkage of proximal myotonic myopathy to chromosome 3q.
Ricker, K., Grimm, T., Koch, M. C., Schneider, C., Kress, W., Reimers, C. D., . . . Mueller, C. R. (1999). Linkage of proximal myotonic myopathy to chromosome 3q.. Neurology, 52(1), 170-171. doi:10.1212/wnl.52.1.170
Peroxisome proliferator-activated receptor gamma gene locus is related to body mass index and lipid values in healthy nonobese subjects.
Knoblauch, H., Busjahn, A., Müller-Myhsok, B., Faulhaber, H. D., Schuster, H., Uhlmann, R., & Luft, F. C. (1999). Peroxisome proliferator-activated receptor gamma gene locus is related to body mass index and lipid values in healthy nonobese subjects.. Arteriosclerosis, thrombosis, and vascular biology, 19(12), 2940-2944. doi:10.1161/01.atv.19.12.2940
Quantitative trait loci for blood pressure exist near the IGF-1, the Liddle syndrome, the angiotensin II-receptor gene and the renin loci in man.
Nagy, Z., Busjahn, A., Bähring, S., Faulhaber, H. D., Gohlke, H. R., Knoblauch, H., . . . Luft, F. C. (1999). Quantitative trait loci for blood pressure exist near the IGF-1, the Liddle syndrome, the angiotensin II-receptor gene and the renin loci in man.. Journal of the American Society of Nephrology : JASN, 10(8), 1709-1716. doi:10.1681/asn.v1081709
Significant evidence for linkage of a simulated trait to D1G024--a conclusion reached using multiallelic transmission/disequilibrium tests.
Ziegler, A., Hebebrand, J., Kastner, C., & Müller-Myhsok, B. (1999). Significant evidence for linkage of a simulated trait to D1G024--a conclusion reached using multiallelic transmission/disequilibrium tests.. In Genetic epidemiology Vol. 17 Suppl 1 (pp. S785-S789). doi:10.1002/gepi.13701707129
hSKCa3: a candidate gene for schizophrenia?
Meissner, B., Purmann, S., Schürmann, M., Zühlke, C., Lencer, R., Arolt, V., . . . Schwinger, E. (1999). hSKCa3: a candidate gene for schizophrenia?. Psychiatric genetics, 9(2), 91-96.
1998
Intra-abdominal Candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality.
Hoerauf, A., Hammer, S., Müller-Myhsok, B., & Rupprecht, H. (1998). Intra-abdominal Candida infection during acute necrotizing pancreatitis has a high prevalence and is associated with increased mortality.. Critical care medicine, 26(12), 2010-2015. doi:10.1097/00003246-199812000-00031
A linkage study of spelling disorder on chromosomes 1, 6, and 15
Schulte-Körne, G., Nöthen, M. M., Cichon, S., Grimm, T., Müller-Myhsok, B., Propping, P., & Remschmidt, H. (1998). A linkage study of spelling disorder on chromosomes 1, 6, and 15. American Journal of Medical Genetics - Neuropsychiatric Genetics, 81(6), 459.
A susceptibility locus for Parkinson's disease maps to chromosome 2p13.
Gasser, T., Müller-Myhsok, B., Wszolek, Z. K., Oehlmann, R., Calne, D. B., Bonifati, V., . . . Horstmann, R. D. (1998). A susceptibility locus for Parkinson's disease maps to chromosome 2p13.. Nature genetics, 18(3), 262-265. doi:10.1038/ng0398-262
Connexin 26 R143W mutation associated with recessive nonsyndromic sensorineural deafness in Africa.
Brobby, G. W., Müller-Myhsok, B., & Horstmann, R. D. (1998). Connexin 26 R143W mutation associated with recessive nonsyndromic sensorineural deafness in Africa.. The New England journal of medicine, 338(8), 548-550. doi:10.1056/nejm199802193380813
Approaches to the genetics of cardiovascular disease through genetic field work.
Schuster, H., Lamprecht, A., Junghans, C., Dietz, B., Baron, H., Nothnagel, M., . . . Luft, F. C. (1998). Approaches to the genetics of cardiovascular disease through genetic field work.. In Kidney international Vol. 53 (pp. 1449-1454). doi:10.1046/j.1523-1755.1998.00928.x
Evidence for linkage of spelling disability to chromosome 15.
Schulte-Körne, G., Grimm, T., Nöthen, M. M., Müller-Myhsok, B., Cichon, S., Vogt, I. R., . . . Remschmidt, H. (1998). Evidence for linkage of spelling disability to chromosome 15.. American journal of human genetics, 63(1), 279-282. doi:10.1086/301919
Genetics of Parkinson's disease
Gasser, T., & Muller-Myhsok, B. (1998). Genetics of Parkinson's disease. In Medizinische Genetik Vol. 10 (pp. 387-390).
Maximum-likelihood expression of the transmission/disequilibrium test and power considerations.
Abel, L., & Müller-Myhsok, B. (1998). Maximum-likelihood expression of the transmission/disequilibrium test and power considerations.. American journal of human genetics, 63(2), 664-667. doi:10.1086/301975
Robustness and power of the maximum-likelihood-binomial and maximum-likelihood-score methods, in multipoint linkage analysis of affected-sibship data.
Abel, L., & Müller-Myhsok, B. (1998). Robustness and power of the maximum-likelihood-binomial and maximum-likelihood-score methods, in multipoint linkage analysis of affected-sibship data.. American journal of human genetics, 63(2), 638-647. doi:10.1086/301958
1997
European Mathematical Genetics Meeting. Munich, Germany, 5-7 April 1997. Abstracts.
European Mathematical Genetics Meeting. Munich, Germany, 5-7 April 1997. Abstracts. (1997). In Annals of human genetics Vol. 61 (pp. 531-550). doi:10.1046/j.1469-1809.1997.6160531.x
Genetic complexity and Parkinson's disease.
Gasser, T., Müller-Myhsok, B., Wszolek, Z. K., Dürr, A., Vaughan, J. R., Bonifati, V., . . . Wood, N. (1997). Genetic complexity and Parkinson's disease.. Science (New York, N.Y.), 277(5324), 388-389.
Genetic analysis of complex diseases.
Müller-Myhsok, B., & Abel, L. (1997). Genetic analysis of complex diseases.. Science (New York, N.Y.), 275(5304), 1328-1329.
Genetic analysis of complex diseases.
Scott, W. K., Pericak-Vance, M. A., & Haines, J. L. (1997). Genetic analysis of complex diseases.. Science (New York, N.Y.), 275(5304), 1327. doi:10.1126/science.275.5304.1327
A xanthomatosis-susceptibility gene may exist in a Syrian family with familial hypercholesterolemia.
Vergopoulos, A., Bajari, T., Jouma, M., Knoblauch, H., Aydin, A., Bähring, S., . . . Schuster, H. (1997). A xanthomatosis-susceptibility gene may exist in a Syrian family with familial hypercholesterolemia.. European journal of human genetics : EJHG, 5(5), 315-323.
De novo rearrangements found in 2% of index patients with spinal muscular atrophy: mutational mechanisms, parental origin, mutation rate, and implications for genetic counseling.
Wirth, B., Schmidt, T., Hahnen, E., Rudnik-Schöneborn, S., Krawczak, M., Müller-Myhsok, B., . . . Zerres, K. (1997). De novo rearrangements found in 2% of index patients with spinal muscular atrophy: mutational mechanisms, parental origin, mutation rate, and implications for genetic counseling.. American journal of human genetics, 61(5), 1102-1111. doi:10.1086/301608
Further evidence suggesting the presence of a locus, on human chromosome 5q31-q33, influencing the intensity of infection with Schistosoma mansoni.
Müller-Myhsok, B., Stelma, F. F., Guissé-Sow, F., Muntau, B., Thye, T., Burchard, G. D., . . . Horstmann, R. D. (1997). Further evidence suggesting the presence of a locus, on human chromosome 5q31-q33, influencing the intensity of infection with Schistosoma mansoni.. American journal of human genetics, 61(2), 452-454. doi:10.1016/s0002-9297(07)64073-7
Mapping undetected mutations within a gene-evidence for two preferential regions in the DMD gene.
Müller-Myhsok, B., Heiland, H. J., Müller, C. R., Meng, G., Grimm, T., & Ott, J. (1997). Mapping undetected mutations within a gene-evidence for two preferential regions in the DMD gene.. Human heredity, 47(2), 61-65. doi:10.1159/000154393
1996
Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease.
Arolt, V., Lencer, R., Nolte, A., Müller-Myhsok, B., Purmann, S., Schürmann, M., . . . Schwinger, E. (1996). Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease.. American journal of medical genetics, 67(6), 564-579. doi:3.0.co;2-r">10.1002/(sici)1096-8628(19961122)67:6<564::aid-ajmg10>3.0.co;2-r
The CYP2D6B allele is not overrepresented in a population of German patients with idiopathic Parkinson's disease.
Gasser, T., Müller-Myhsok, B., Supala, A., Zimmer, E., Wieditz, G., Wszolek, Z. K., . . . Oertel, W. H. (1996). The CYP2D6B allele is not overrepresented in a population of German patients with idiopathic Parkinson's disease.. Journal of neurology, neurosurgery, and psychiatry, 61(5), 518-520. doi:10.1136/jnnp.61.5.518
Identification of a key recombinant narrows the CADASIL gene region to 8 cM and argues against allelism of CADASIL and familial hemiplegic migraine.
Dichgans, M., Mayer, M., Müller-Myhsok, B., Straube, A., & Gasser, T. (1996). Identification of a key recombinant narrows the CADASIL gene region to 8 cM and argues against allelism of CADASIL and familial hemiplegic migraine.. Genomics, 32(1), 151-154. doi:10.1006/geno.1996.0094
Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan.
Veske, A., Oehlmann, R., Younus, F., Mohyuddin, A., Müller-Myhsok, B., Mehdi, S. Q., & Gal, A. (1996). Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan.. Human molecular genetics, 5(1), 165-168. doi:10.1093/hmg/5.1.165
European Gene Mapping Project (EUROGEM): breakpoint panels for human chromosomes based on the CEPH reference families. Centre d'Etude du Polymorphisme Humain.
Cox, S. A., Attwood, J., Bryant, S. P., Bains, R., Povey, S., Rebello, M., . . . Spurr, N. K. (1996). European Gene Mapping Project (EUROGEM): breakpoint panels for human chromosomes based on the CEPH reference families. Centre d'Etude du Polymorphisme Humain.. Annals of human genetics, 60(6), 447-486. doi:10.1111/j.1469-1809.1996.tb01614.x