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Research

Research Interest 1

Role of microenveronment in cancer initiation and progression

Research grants

MRes in Biomedical Sciences, Biology of Cancer Strand

NORTH WEST CANCER RESEARCH FUND

January 2009 - December 2012

Four year PhD programme in Cellular and Molecular Physiology.

WELLCOME TRUST (UK)

October 2005 - September 2009

Gut-Brain Signalling: Roles of Lipid, Cholecystokinin and the Vagus Nerve in Man.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

October 1999 - October 2002

The neuroendocrinology of the upper gastrointestinal tract

MEDICAL RESEARCH COUNCIL

October 1998 - September 2003

Bridging and accelerating the translation of novel scientific findings for health and wealth gain

MEDICAL RESEARCH COUNCIL

March 2014 - August 2015

Identification of patients at risk of gastric cancer

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

February 2014 - January 2015

Quantitative high-throughput proteomics for biomedical research.

MEDICAL RESEARCH COUNCIL

March 2005 - March 2008

The endocrinology of the upper gastrointestinal tract.

MEDICAL RESEARCH COUNCIL

October 2003 - September 2008

Identification of novel stromal targets for early detection and targeted therapy in pancreatic and oesophageal cancer

CANCER RESEARCH UK (UK)

July 2010 - September 2011

Actions of cholecystokinin on vagal afferent neurons

WELLCOME TRUST (UK)

December 2009 - January 2013

Vacation Scholarship. Characterisation of epithelial mesenchymal interactions in the oesophageus.

WELLCOME TRUST (UK)

July 2008 - September 2008

Regulated and deregulated secretion from primary myofibroblasts in gastric cancer.

NORTH WEST CANCER RESEARCH FUND

October 2008 - September 2011

Myofibroblast control of oesophageal squamous cancer invasion: role of chemerin

NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

February 2015 - December 2018

Maintaining functional integrity of gastric epithelium:identification of novel transcriptional mechanisms.

WELLCOME TRUST (UK)

March 2010 - June 2013

Nutrient modulation of vagal afferent signalling.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

September 2006 - August 2009

Gut-brain signalling in man: modulation of the cholecystokinin-vagus nerve pathway.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

May 2003 - September 2006

Bench fees for Hanan M Garalla

LIBYAN EMBASSY IN LONDON🚩

July 2013 - June 2016

Four-year PhD programme in cellular and molecular physiology.

WELLCOME TRUST (UK)

October 2004 - September 2008

Four year PhD Programme (2008)

WELLCOME TRUST (UK)

October 2008 - December 2012

Importance of alternative pathway NF-κB signalling in Helicobacter-induced gastric carcinogenesis

NORTH WEST CANCER RESEARCH FUND

January 2013 - September 2016

Validation and exploitation of biomarkers for identification of patients at risk of gastric cancer

NORTH WEST CANCER RESEARCH FUND

November 2012 - October 2014

Application of automated, high-content, live-cell, fluorescence imaging in multidisciplinary studies of epithelial, neuronal and stem cell function.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

April 2007 - March 2008

Identification of patients at risk of gastric cancer

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

April 2012 - September 2013

Four year PhD Programme in Cellular and Molecular Physiology.

WELLCOME TRUST (UK)

October 2000 - November 2004

Four year PhD Programme in Cellular and Molecular Physiology.

WELLCOME TRUST (UK)

October 2003 - September 2007

Developing a collaborative resource for ChIP based analyses of cancer related transcriptional networks

CANCER RESEARCH UK (UK)

April 2012 - March 2013

Towards disease diagnosis through spectrochemical imaging of tissue architecture.

ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL

June 2013 - September 2016

Capacity building award in integrative mammalian biology

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

January 2007 - October 2015

Investigation of the importance of the gastrin family of peptides and gastrin/CCKb receptor in inflammatory bowel disease.

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

September 2003 - September 2007

Investigation of the mechanisms by which progastrin promotes colonic carcinogenesis.

NORTH WEST CANCER RESEARCH FUND

June 2006 - December 2010

YEAR 1 (part2) Wellcome Trust ISSF Non-Clinical Fellowships

WELLCOME TRUST (UK)

October 2012 - March 2023

How does the microbiome of the hypochlorhydric stomach promote gastric tumourigenesis?

WORLDWIDE CANCER RESEARCH (UK)

November 2012 - October 2015

The effect of gastrin on gastric tubulogenesis.

WELLCOME TRUST (UK)

October 1999 - September 2003

Wellcome Trust 3 year PhD - cellular and molecular physiology

WELLCOME TRUST (UK)

October 2010 - September 2013

Identification of patients at risk of gastric cancer due to helicobacter pylori infection

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2007 - March 2012

Role of MMP-7 in the pathogenesis of gastric cancer.

NORTH WEST CANCER RESEARCH FUND

November 2003 - November 2006

YEAR 1 Wellcome Trust ISSF Non-Clinical Fellowships

WELLCOME TRUST (UK)

October 2011 - May 2018

    Research collaborations

    Dan Palmer

    Dr Peter Hegy

    University of Szeged Medical School

    Characterisation of epithelial & mesenchymal transporters in the gastrointestinal (GI) tract. Regulation of the stem cell niche in the GI tract.

    Prof Tim Wang

    Columbia University Medical & Irving Cancer Research Center , New York

    Regulation of the gastric stem cell niche

    Dr Mark Pritchard

    Obtaining clinical samples.

    Profs Dockray, Varro, and Dimaline

    Collaboration on role of gastrin in gastrointestinal physiology

    Profs Dockray, Varro and Dimaline

    Dockray, Varro, Dimaline and group

    Gastrin and apoptosis