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Professor Andrea Jorgensen
PhD MSc BA ATT ATII

Professor, Biostatistics
Health Data Science
Part of
Institute of Population Health
Faculty of Health and Life Sciences

Contact

A.L.Jorgensen@liverpool.ac.uk

Publications

Selected publications

  1. A Randomized Trial of Genotype-Guided Dosing of Warfarin (Journal article - 2013)
  2. STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline (Journal article - 2020)
  3. Biomarker-guided trials: Challenges in practice (Journal article - 2019)
  4. Evidence to Support Inclusion of Pharmacogenetic Biomarkers in Randomised Controlled Trials (Journal article - 2019)
  5. Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study (Journal article - 2019)
  6. NAT2 variants and toxicity related to anti-tuberculosis agents: a systematic review and meta-analysis (Journal article - 2019)
  7. Association of variants within the <i>GST</i> and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis (Journal article - 2019)
  8. <i>CYP</i> genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis (Journal article - 2018)
  9. A genome-wide association study of stable warfarin dose in sub-Saharan African patients (Conference Paper - 2023)
  10. Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study (Journal article - 2018)
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2024

OP0277 EVALUATING THE IMPACT OF CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS T2T TARGET ATTAINMENT: MITIGATING FLARES AND NEW DAMAGE ACCRUAL

Sarker, C., Jorgensen, A. L., Beresford, M. W., & MD Smith, E. (2024). OP0277 EVALUATING THE IMPACT OF CHILDHOOD-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS T2T TARGET ATTAINMENT: MITIGATING FLARES AND NEW DAMAGE ACCRUAL. In Scientific Abstracts (pp. 229). BMJ Publishing Group Ltd and European League Against Rheumatism. doi:10.1136/annrheumdis-2024-eular.697

DOI
10.1136/annrheumdis-2024-eular.697
Conference Paper

POS0173 EVALUATING CHILDHOOD LUPUS LOW DISEASE ACTIVITY STATE (cLLDAS) AS A POTENTIAL TREAT-TO-TARGET TREATMENT ENDPOINT: A VALIDATION AND SENSITIVITY ANALYSIS

Smith, E. M., Sarker, C., Jorgensen, A. L., & Beresford, M. W. (2024). POS0173 EVALUATING CHILDHOOD LUPUS LOW DISEASE ACTIVITY STATE (cLLDAS) AS A POTENTIAL TREAT-TO-TARGET TREATMENT ENDPOINT: A VALIDATION AND SENSITIVITY ANALYSIS. In Scientific Abstracts (pp. 529). BMJ Publishing Group Ltd and European League Against Rheumatism. doi:10.1136/annrheumdis-2024-eular.5896

DOI
10.1136/annrheumdis-2024-eular.5896
Conference Paper

Genetic Determinants of Thiazide-Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances - A Genome-Wide Evaluation of the UK Biobank.

Asiimwe, I. G., Walker, L., Sofat, R., Jorgensen, A. L., Pirmohamed, M., & Multimorbidity Mechanism and Therapeutic Research Collaborative (MMTRC). (2024). Genetic Determinants of Thiazide-Induced Hyperuricemia, Hyperglycemia, and Urinary Electrolyte Disturbances - A Genome-Wide Evaluation of the UK Biobank.. Clinical pharmacology and therapeutics. doi:10.1002/cpt.3229

DOI
10.1002/cpt.3229
Journal article

2023

A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study

Jorgensen, A. L., Orrell, C., Waitt, C., Toh, C. -H., Sekaggya-Wiltshire, C., Hughes, D. A., . . . Pirmohamed, M. (2023). A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study. JMIR RESEARCH PROTOCOLS, 12. doi:10.2196/46710

DOI
10.2196/46710
Journal article

A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study (Preprint)

DOI
10.2196/preprints.46710
Preprint

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

Hurkmans, E. G. E., Klumpers, M. J., Dello Russo, C., De Witte, W., Guchelaar, H. -J., Gelderblom, H., . . . Te Loo, D. M. W. M. (2023). Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.. Frontiers in pharmacology, 13, 980309. doi:10.3389/fphar.2022.980309

DOI
10.3389/fphar.2022.980309
Journal article

<i>CYP3A</i> genetic variation and taxane-induced peripheral neuropathy: a systematic review, meta-analysis, and candidate gene study (vol 14, 1178421, 2023)

Mcevoy, L., Cliff, J., Carr, D. F., Jorgensen, A., Lord, R., & Pirmohamed, M. (2023). <i>CYP3A</i> genetic variation and taxane-induced peripheral neuropathy: a systematic review, meta-analysis, and candidate gene study (vol 14, 1178421, 2023). FRONTIERS IN PHARMACOLOGY, 14. doi:10.3389/fphar.2023.1274075

DOI
10.3389/fphar.2023.1274075
Journal article

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan Black-African patients

Asiimwe, I., Zhang, E., Jorgensen, A., & Pirmohamed, M. (2023). A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan Black-African patients. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 89 (pp. 1248-1249). Retrieved from https://www.webofscience.com/

Conference Paper

A genome-wide association study of stable warfarin dose in sub-Saharan African patients

Asiimwe, I., Zhang, E., Jorgensen, A., & Pirmohamed, M. (2023). A genome-wide association study of stable warfarin dose in sub-Saharan African patients. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 89 (pp. 1249). Retrieved from https://www.webofscience.com/

Conference Paper

Blood group as a clinical risk factor in peptic ulcer disease: UK biobank analysis

McEvoy, L., Pirmohamed, M., Carr, D., & Jorgensen, A. (2023). Blood group as a clinical risk factor in peptic ulcer disease: UK biobank analysis. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 89 (pp. 1243). Retrieved from https://www.webofscience.com/

Conference Paper

Clinical Risk Factors in Peptic Ulcer Disease: UK Biobank Analysis

McEvoy, L., Pirmohamed, M., Carr, D., & Jorgensen, A. (2023). Clinical Risk Factors in Peptic Ulcer Disease: UK Biobank Analysis. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 180 (pp. 276). Retrieved from https://www.webofscience.com/

Conference Paper

Developing a warfarin dosing algorithm in patients with mechanical heart valves

Zhang, E., Stewart, A., Jorgensen, A., McEvoy, L., Carracedo, A. D., Foster, T., . . . Pirmohamed, M. (2023). Developing a warfarin dosing algorithm in patients with mechanical heart valves. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 89 (pp. 1249-1250). Retrieved from https://www.webofscience.com/

Conference Paper

Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study

Kuan, V., Denaxas, S., Patalay, P., Nitsch, D., Mathur, R., Gonzalez-Izquierdo, A., . . . MMTRC. (2023). Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. LANCET DIGITAL HEALTH, 5(1), E16-E27. doi:10.1016/S2589-7500(22)00187-X

DOI
10.1016/S2589-7500(22)00187-X
Journal article

2022

Genetic Association Analysis of Epilepsy Prognosis Using Whole Exome Sequencing

Shankar, R. G., Morris, A. P., Sills, G., Marson, T., & Jorgensen, A. (2022). Genetic Association Analysis of Epilepsy Prognosis Using Whole Exome Sequencing. In GENETIC EPIDEMIOLOGY Vol. 46 (pp. 530-531). Retrieved from https://www.webofscience.com/

Conference Paper

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.

Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.. Frontiers in pharmacology, 13, 967082. doi:10.3389/fphar.2022.967082

DOI
10.3389/fphar.2022.967082
Journal article

A review of software tools for statistical tests of genetic association with rare variants using next generation sequence data

DOI
10.31219/osf.io/g83ed
Preprint

459 Nephrotoxin-associated AKI in non-critically ill children: A single centre prospective audit

Hankinson, C., Oni, L., Jorgensen, A., & McWilliam, S. (2022). 459 Nephrotoxin-associated AKI in non-critically ill children: A single centre prospective audit. In British Association for Community Child Health (pp. A92.3-A93). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.150

DOI
10.1136/archdischild-2022-rcpch.150
Conference Paper

GENOME WIDE ANALYSIS IDENTIFIES POTENTIAL MECHANISMS OF NON-ALCOHOLIC FATTY LIVER DISEASE

Ho, B., Thompson, A., Jorgensen, A., & Pirmohamed, M. (2022). GENOME WIDE ANALYSIS IDENTIFIES POTENTIAL MECHANISMS OF NON-ALCOHOLIC FATTY LIVER DISEASE. In GUT Vol. 71 (pp. A14-A15). doi:10.1136/gutjnl-2022-BSG.25

DOI
10.1136/gutjnl-2022-BSG.25
Conference Paper

978-3-319-52677-5

Jorgensen, A., Brown, L., Antoniou, M., & Wason, J. (2022). 978-3-319-52677-5. In S. Piantadosi, & C. Meinert (Eds.), Principles and practice of clinical trials. Springer.

Chapter

Biomarker-Guided Trials

Brown, L. C., Jorgensen, A. L., Antoniou, M., & Wason, J. (2022). Biomarker-Guided Trials. In Principles and Practice of Clinical Trials (pp. 1-26). Springer International Publishing. doi:10.1007/978-3-319-52677-5_168-2

DOI
10.1007/978-3-319-52677-5_168-2
Chapter

Biomarker-Guided Trials

Brown, L. C., Jorgensen, A. L., Antoniou, M., & Wason, J. (2022). Biomarker-Guided Trials. In Principles and Practice of Clinical Trials (pp. 1145-1170). Springer International Publishing. doi:10.1007/978-3-319-52636-2_168

DOI
10.1007/978-3-319-52636-2_168
Chapter

Polygenic risk score analysis reveals shared genetic burden between epilepsy and psychiatric comorbidities

Campbell, C., Lewis-Smith, D., Leu, C., Martins, H., Krause, R., O'Brien, T., . . . Cavalleri, G. L. (2022). Polygenic risk score analysis reveals shared genetic burden between epilepsy and psychiatric comorbidities. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 30 (pp. 31-32). Retrieved from https://www.webofscience.com/

Conference Paper

Selecting subsets of immune repertoire features improves prediction of coeliac disease status using machine learning

Kockelbergh, H., Shoukat, M. S., Evans, S. C., Brierley, L., Jorgensen, A. L., Green, P. L., . . . Fowler, A. (2022). Selecting subsets of immune repertoire features improves prediction of coeliac disease status using machine learning. In HUMAN HEREDITY Vol. VOL. (pp. 14-15). Retrieved from https://www.webofscience.com/

Conference Paper

Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm

Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm. CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 11(1), 20-29. doi:10.1002/psp4.12740

DOI
10.1002/psp4.12740
Journal article

2021

Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda (vol 109, pg 1564, 2021)

Asiimwe, I. G., Waitt, C., Sekaggya-Wiltshire, C., Hutchinson, C., Okello, E., Zhang, E. J., . . . Pirmohamed, M. (2021). Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda (vol 109, pg 1564, 2021). CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(5), 1402. doi:10.1002/cpt.2395

DOI
10.1002/cpt.2395
Journal article

1136 Drug-induced acute kidney injury in non-critically ill, hospitalised children: a systematic review and meta-analysis

Hankinson, C., Oni, L., Jorgensen, A., & McWilliam, S. (2021). 1136 Drug-induced acute kidney injury in non-critically ill, hospitalised children: a systematic review and meta-analysis. In Abstracts (pp. A243.1-A243). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2021-rcpch.423

DOI
10.1136/archdischild-2021-rcpch.423
Conference Paper

1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study

Egbivwie, N., Jorgensen, A. L., Beresford, M. W., Hedrich, C. M., & Smith, E. M. D. (2021). 1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study. In Abstracts (pp. A454). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2021-rcpch.790

DOI
10.1136/archdischild-2021-rcpch.790
Conference Paper

ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.

Karimi, L., Vijverberg, S. J., Engelkes, M., Hernandez-Pacheco, N., Farzan, N., Soares, P., . . . PiCA, SysPharmPedia consortia. (2021). ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. doi:10.1111/cea.13965

DOI
10.1111/cea.13965
Journal article

Warfarin dosing algorithms: A systematic review

Asiimwe, I. G., Zhang, E. J., Osanlou, R., Jorgensen, A. L., & Pirmohamed, M. (2021). Warfarin dosing algorithms: A systematic review. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(4), 1717-1729. doi:10.1111/bcp.14608

DOI
10.1111/bcp.14608
Journal article

Biomarker-Guided Trials

Brown, L. C., Jorgensen, A. L., Antoniou, M., & Wason, J. (2021). Biomarker-Guided Trials. In Principles and Practice of Clinical Trials (pp. 1-26). Springer International Publishing. doi:10.1007/978-3-319-52677-5_168-1

DOI
10.1007/978-3-319-52677-5_168-1
Chapter

Clinical and pharmacogenetic determinants of tenofovir-induced renal toxicity in HIV positive patients in Zambia

Hamachila, A., Pushpakom, S., Jorgensen, A., & Pirmohamed, M. (2021). Clinical and pharmacogenetic determinants of tenofovir-induced renal toxicity in HIV positive patients in Zambia. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 4889). Retrieved from https://www.webofscience.com/

Conference Paper

Meta-Analysis of Genome-Wide Association Studies of Exacerbations in Children Using Long-Acting Beta-Agonists

Slob, E., Richards, L. B., Vijverberg, S., Longo, C., Koppelman, G. H., Pijnenburg, M. W., . . . Maitland-van der Zee, A. H. (2021). Meta-Analysis of Genome-Wide Association Studies of Exacerbations in Children Using Long-Acting Beta-Agonists. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 203. Retrieved from https://www.webofscience.com/

Conference Paper

2020

Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load.

Perucca, P., Anderson, A., Jazayeri, D., Hitchcock, A., Graham, J., Todaro, M., . . . EpiPGX and EPIGEN Consortia. (2020). Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load.. Annals of neurology, 87(6), 897-906. doi:10.1002/ana.25724

DOI
10.1002/ana.25724
Journal article

Whole exome sequencing analysis of complex "Time-To-Event" outcomes in epilepsy patients

Shankar, R. G., Morris, A. P., Sills, G., Marson, T., & Jorgensen, A. (2020). Whole exome sequencing analysis of complex "Time-To-Event" outcomes in epilepsy patients. In GENETIC EPIDEMIOLOGY Vol. 44 (pp. 484). Retrieved from https://www.webofscience.com/

Conference Paper

2019

Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

Carr, D. (2019). Genomewide Association Study of Statin‐Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink. Clinical Pharmacology and Therapeutics, 106(6), 1353-1361. doi:10.1002/cpt.1557

DOI
10.1002/cpt.1557
Journal article

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.16.8.11

DOI
10.1530/ey.16.8.11
Journal article

Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies

Richardson, M., Kirkham, J. J., Dwan, K. M., Sloan, D. J., Davies, G., & Jorgensen, A. (2019). Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies. BMJ OPEN, 9(7). doi:10.1136/bmjopen-2019-030212

DOI
10.1136/bmjopen-2019-030212
Journal article

HMGB1 expression in SJS/TEN sera and skin

Carr, D. F., Wang, C., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., . . . Pirmohamed, M. (2019). HMGB1 expression in SJS/TEN sera and skin. British Journal of Dermatology, 181(1). doi:10.1111/bjd.18061

DOI
10.1111/bjd.18061
Journal article

Serum and blister-fluid elevation and decreased epidermal content of high-mobility group box 1 protein in drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis

Carr, D. F., Wang, C. -W., Bellon, T., Ressel, L., Nwikue, G., Shrivastava, V., . . . Pirmohamed, M. (2019). Serum and blister-fluid elevation and decreased epidermal content of high-mobility group box 1 protein in drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. BRITISH JOURNAL OF DERMATOLOGY, 181(1), 166-174. doi:10.1111/bjd.17610

DOI
10.1111/bjd.17610
Journal article

药物引发的史蒂文斯‐约翰逊综合征/中毒性表皮坏死松解症患者血清及水泡液中高迁移率族蛋白 B 的蛋白含量高迁移率族

Carr, D. F., Wang, C., Bellón, T., Ressel, L., Nwikue, G., Shrivastava, V., . . . Pirmohamed, M. (2019). 药物引发的史蒂文斯‐约翰逊综合征/中毒性表皮坏死松解症患者血清及水泡液中高迁移率族蛋白 B 的蛋白含量高迁移率族. British Journal of Dermatology, 181(1). doi:10.1111/bjd.18080

DOI
10.1111/bjd.18080
Journal article

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy (Retraction of Vol 127, Pg 2118, 2017)

Walker, L. E., Frigerio, F., Ravizza, T., Ricci, E., Tse, K., Jenkins, R. E., . . . Pirmohamed, M. (2019). Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy (Retraction of Vol 127, Pg 2118, 2017). JOURNAL OF CLINICAL INVESTIGATION, 129(5), 2166. doi:10.1172/JCI129285

DOI
10.1172/JCI129285
Journal article

A discrete choice experiment to measure public preferences for genetic testing to prevent adverse drug reactions

Johnson, D., Jorgensen, A., Hughes, D., & Pirmohamed, S. M. (2019). A discrete choice experiment to measure public preferences for genetic testing to prevent adverse drug reactions. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/

Conference Paper

2018

Growing international evidence for urinary biomarker panels identifying lupus nephritis in children - verification within the South African Paediatric Lupus Cohort

Smith, E. M. D., Lewandowski, L. B., Jorgensen, A. L., Phuti, A., Nourse, P., Scott, C., & Beresford, M. W. (2018). Growing international evidence for urinary biomarker panels identifying lupus nephritis in children - verification within the South African Paediatric Lupus Cohort. LUPUS, 27(14), 2190-2199. doi:10.1177/0961203318808376

DOI
10.1177/0961203318808376
Journal article

A comparison of joint models for longitudinal and competing risks data, with application to an epilepsy drug randomized controlled trial

Hickey, G., Philipson, P., Jorgensen, A., & Kolamunnage-Dona, R. (2018). A comparison of joint models for longitudinal and competing risks data, with application to an epilepsy drug randomized controlled trial. Journal of the Royal Statistical Society Series A: Statistics in Society, 181(04), 1105-1123. doi:10.1111/rssa.12348

DOI
10.1111/rssa.12348
Journal article

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.15.8.6

DOI
10.1530/ey.15.8.6
Journal article

PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer

Carter, R. J., Butterworth, M., Risk, J. M., Jorgensen, A. L., Sacco, J. J., Schache, A. G., . . . Varadarajan, S. (2018). PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer. In ESMO Open Vol. 3 (pp. A238). Elsevier BV. doi:10.1136/esmoopen-2018-eacr25.562

DOI
10.1136/esmoopen-2018-eacr25.562
Conference Paper

WITHDRAWN: Reference intervals for putative biomarkers of drug-induced liver injury and liver regeneration in healthy human volunteers.

Francis, B., Clarke, J. I., Walker, L. E., Brillant, N., Jorgensen, A. L., Park, B. K., . . . Antoine, D. J. (2018). WITHDRAWN: Reference intervals for putative biomarkers of drug-induced liver injury and liver regeneration in healthy human volunteers.. Journal of hepatology, S0168-8278(18)32042-7. doi:10.1016/j.jhep.2018.04.024

DOI
10.1016/j.jhep.2018.04.024
Journal article

2017

GWAS FOR EARLY REMISSION IN NEWLY DIAGNOSED FOCAL EPILEPSY

Auce, P., Francis, B., Langley, S. R., Jorgensen, A., Marson, A. G., & Sills, G. J. (2017). GWAS FOR EARLY REMISSION IN NEWLY DIAGNOSED FOCAL EPILEPSY. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A22). doi:10.1136/jnnp-2017-ABN.73

DOI
10.1136/jnnp-2017-ABN.73
Conference Paper

The molecular genetics of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis

Cliff, J., Jorgensen, A. L., Lord, R., Azam, F., Cossar, L., Carr, D. F., & Pirmohamed, M. (2017). The molecular genetics of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 120, 127-140. doi:10.1016/j.critrevonc.2017.09.009

DOI
10.1016/j.critrevonc.2017.09.009
Journal article

Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt - 1)/PlGF ratio, comparison of predictive accuracy for preeclampsia, and relation to uterine artery Doppler and response to aspirin

Navaratnam, K., Abreu, P., Clarke, H., Jorgensen, A., Alfirevic, A., & Alfirevic, Z. (2017). Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt - 1)/PlGF ratio, comparison of predictive accuracy for preeclampsia, and relation to uterine artery Doppler and response to aspirin. The Journal of Maternal-Fetal and Neonatal Medicine, 32(2), 179-187. doi:10.1080/14767058.2017.1373760

DOI
10.1080/14767058.2017.1373760
Journal article

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

Lomakina, O., Alekseeva, E., Valieva, S., Bzarova, T., Nikishina, I., Zholobova, E., . . . Rose, C. (2017). Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two. Pediatric Rheumatology, 15(S1). doi:10.1186/s12969-017-0142-8

DOI
10.1186/s12969-017-0142-8
Journal article

Development and Application of Methodology for the Analysis of Rare Genetic Variants with Time to Event Outcomes Using SurvivalGWAS_RV

Syed, H., Jorgensen, A. L., & Morris, A. P. (2017). Development and Application of Methodology for the Analysis of Rare Genetic Variants with Time to Event Outcomes Using SurvivalGWAS_RV. In GENETIC EPIDEMIOLOGY Vol. 41 (pp. 685-686). Retrieved from https://www.webofscience.com/

Conference Paper

Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome

Turner, R. M., Yin, P., Hanson, A., FitzGerald, R., Morris, A. P., Stables, R. H., . . . Pirmohamed, M. (2017). Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome. Journal of Clinical Lipidology, 11(1), 204-214. doi:10.1016/j.jacl.2016.12.007

DOI
10.1016/j.jacl.2016.12.007
Journal article

2016

A comparison of HMGB1 concentrations between cerebrospinal fluid and blood in patients with neurological disease

Walker, L., Griffiths, M. J., McGill, F., Lewthwaite, P., Sills, G. J., Jorgensen, A., . . . Pirmohamed, M. (2016). A comparison of HMGB1 concentrations between cerebrospinal fluid and blood in patients with neurological disease. Biomarkers, 22(7), 635-642. doi:10.1080/1354750X.2016.1265003

DOI
10.1080/1354750X.2016.1265003
Journal article

Joint modelling of longitudinal outcomes and clinical endpoints: JoineR & JoineR-M

Hickey, G. L., Philipson, P., Jorgensen, A., Henderson, R., Diggle, P., Williamson, P., & Kolamunnage-Dona, R. (2016). Joint modelling of longitudinal outcomes and clinical endpoints: JoineR & JoineR-M. Poster session presented at the meeting of MRC Festival of Medical Research. Victoria Gallery and Museum, University of Liverpool.

Poster

Adrenal responses to a low-dose short synacthen test in children with asthma (vol 82, pg 648, 2015)

Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2016). Adrenal responses to a low-dose short synacthen test in children with asthma (vol 82, pg 648, 2015). CLINICAL ENDOCRINOLOGY, 84(5), 793. doi:10.1111/cen.13069

DOI
10.1111/cen.13069
Journal article

Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

Antoniou, M., Jorgensen, A. L., & Kolamunnage-Dona, R. (2016). Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review. PLoS One, 11(2). doi:10.1371/journal.pone.0149803

DOI
10.1371/journal.pone.0149803
Journal article

A Genome-Wide Two-Component Mixture Model Expectation-Maximisation Algorithm for Time to Event Data

Francis, B., Yin, P., Cook, J. P., Jorgensen, A. L., Hutton, J., & Morris, A. P. (2016). A Genome-Wide Two-Component Mixture Model Expectation-Maximisation Algorithm for Time to Event Data. In HUMAN HEREDITY Vol. 81 (pp. 212-213). Retrieved from https://www.webofscience.com/

Conference Paper

SurvivalGWAS_RV: Software to Test Rare Variant Association with "Time-to-Event" Outcomes

Syed, H., Jorgensen, A. L., & Morris, A. P. (2016). SurvivalGWAS_RV: Software to Test Rare Variant Association with "Time-to-Event" Outcomes. In HUMAN HEREDITY Vol. 81 (pp. 230). Retrieved from https://www.webofscience.com/

Conference Paper

2015

Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury

Antoine, D., Sabbisetti, V., Francis, B., Jorgensen, A., Craig, D., Simpson, K., . . . Dear, J. (2015). Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury. Hepatology, 62(2), 591-599. doi:10.1002/hep.27857

DOI
10.1002/hep.27857
Journal article

HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity: a systematic review of the literature and meta-analysis.

Cornejo Castro, E. M., Carr, D., Jorgensen, A., Alfirevic, A., & Pirmohamed, M. (2015). HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity: a systematic review of the literature and meta-analysis.. Pharmacogenetics and genomics, 25(04), 186-198. doi:10.1097/FPC.0000000000000124

DOI
10.1097/FPC.0000000000000124
Journal article

Evaluating statistical characteristics of biomarker-guided trial designs

Antoniou, M., Jorgensen, A., & Kolamunnage-Dona, R. (2015). Evaluating statistical characteristics of biomarker-guided trial designs. TRIALS, 16. doi:10.1186/1745-6215-16-S2-O83

DOI
10.1186/1745-6215-16-S2-O83
Journal article

Evaluation of methodology for the analysis of "time-toevent" data in pharmacogenetic studies

Syed, H., Jorgensen, A., & Morris, A. P. (2015). Evaluation of methodology for the analysis of "time-toevent" data in pharmacogenetic studies. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 584). Retrieved from https://www.webofscience.com/

Conference Paper

Genome-Wide Two-Way Competing Risks Approach to Analyse Time to Antiepileptic Drug Withdrawal

Francis, B., Jorgensen, A., Morris, A., Ingason, A., Marson, A., Johnson, M., & Sills, G. (2015). Genome-Wide Two-Way Competing Risks Approach to Analyse Time to Antiepileptic Drug Withdrawal. In HUMAN HEREDITY Vol. 80 (pp. 109-110). Retrieved from https://www.webofscience.com/

Conference Paper

Pharmacogenetics of Acute Coronary Syndrome

Yin, P., Jorgensen, A., Morris, A. P., Turner, R., Fitzgerald, R., Stables, R., . . . Pirmohamed, M. (2015). Pharmacogenetics of Acute Coronary Syndrome. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 596). Retrieved from https://www.webofscience.com/

Conference Paper

Powerful Methodology for the Analysis of 'Time-to-Event' Data in Pharmacogenetic Studies

Syed, H., Jorgensen, A., & Morris, A. (2015). Powerful Methodology for the Analysis of 'Time-to-Event' Data in Pharmacogenetic Studies. In HUMAN HEREDITY Vol. 79 (pp. 46-47). Retrieved from https://www.webofscience.com/

Conference Paper

The Influence of Pharmacogenetics on the Time to Acute Coronary Syndrome Recurrence in a UK Cohort Study

Yin, P., Jorgensen, A., Morris, A., Turner, R., Fitzgerald, R., Stables, R., . . . Pirmohamed, M. (2015). The Influence of Pharmacogenetics on the Time to Acute Coronary Syndrome Recurrence in a UK Cohort Study. In HUMAN HEREDITY Vol. 80 (pp. 123). Retrieved from https://www.webofscience.com/

Conference Paper

Two-Component Mixture Modelling Approach Integrating Genetic and Clinical Variables in Analysis of Time to First Seizure in Epilepsy

Francis, B., Jorgensen, A., Morris, A., Marson, A., Johnson, M., & Sills, G. (2015). Two-Component Mixture Modelling Approach Integrating Genetic and Clinical Variables in Analysis of Time to First Seizure in Epilepsy. In HUMAN HEREDITY Vol. 79 (pp. 34). Retrieved from https://www.webofscience.com/

Conference Paper

tSNR as Feature Selection Technique in SNP Data Analysis

Hassan, N., Garcia-Finana, M., Czanner, G., & Jorgensen, A. (2015). tSNR as Feature Selection Technique in SNP Data Analysis. In HUMAN HEREDITY Vol. 80 (pp. 112). Retrieved from https://www.webofscience.com/

Conference Paper

2014

A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction

Francis, B., Lane, S., Pirmohamed, M., & Jorgensen, A. (2014). A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction. PLoS One, 9(12). doi:10.1371/journal.pone.0114896

DOI
10.1371/journal.pone.0114896
Journal article

Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.

Hawcutt, D., Ghani, A., Sutton, L., Jorgensen, A., Zhang, E., Murray, M., . . . Pirmohamed, M. (2014). Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.. The Pharmacogenomics Journal, 14(6), 542-548. doi:10.1038/tpj.2014.31

DOI
10.1038/tpj.2014.31
Journal article

WHICH GENETIC PATHWAYS UNDERLIE PHARMACORESISTANT EPILEPSY?

Mirza, N., Jorgensen, A., Sills, G., Johnson, M., Pirmohamed, M., & Marson, T. (2014). WHICH GENETIC PATHWAYS UNDERLIE PHARMACORESISTANT EPILEPSY?. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 85. doi:10.1136/jnnp-2014-309236.6

DOI
10.1136/jnnp-2014-309236.6
Conference Paper

Cervical stitch (cerclage) for preventing preterm birth in multiple pregnancy

Alfirevic, Z., Rafael, T. J., & Berghella, V. (2014). Cervical stitch (cerclage) for preventing preterm birth in multiple pregnancy. Cochrane Database of Systematic Reviews, 2014(9), 1-55. doi:10.1002/14651858.CD009166.pub2

DOI
10.1002/14651858.CD009166.pub2
Journal article

CYP2B6*18 is associated with nevirpine hypersensitivity independently of HLA-C*04:01 in a Malawian HIV population

Carr, D., Chaponda, M., Castro, E. C., Jorgensen, A., Khoo, S., & Pirmohamed, M. (2014). CYP2B6*18 is associated with nevirpine hypersensitivity independently of HLA-C*04:01 in a Malawian HIV population. Clinical and translational allergy, 4(Suppl 3), P126. doi:10.1186/2045-7022-4-s3-p126

DOI
10.1186/2045-7022-4-s3-p126
Journal article

A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy

Speed, D., Hoggart, C., Petrovski, S., Tachmazidou, I., Coffey, A., Jorgensen, A., . . . Johnson, M. R. (2014). A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy. Human Molecular Genetics, 23(1), 247-258. doi:10.1093/hmg/ddt403

DOI
10.1093/hmg/ddt403
Journal article

IDENTIFYING THE CAUSES OF PHARMACORESISTANT EPILEPSY THROUGH A GENOME-WIDE ASSOCIATION STUDY WITH PATHWAY AND NETWORK ANALYSIS: FROM COMPLEXITY TO COHERENCE TO CENTRALITY

Mirza, N., Jorgensen, A., Sills, G., Johnson, M., Pirmohamed, M., & Marson, A. G. (2014). IDENTIFYING THE CAUSES OF PHARMACORESISTANT EPILEPSY THROUGH A GENOME-WIDE ASSOCIATION STUDY WITH PATHWAY AND NETWORK ANALYSIS: FROM COMPLEXITY TO COHERENCE TO CENTRALITY. In EPILEPSIA Vol. 55 (pp. 10). Retrieved from https://www.webofscience.com/

Conference Paper

Identifying the causes of pharmacoresistant epilepsy through a genome-wide association study with pathway and network analysis: from complexity to coherence to centrality

Mirza, N., Sills, G., Jorgensen, A., Johnson, M., Pirmohamed, M., & Marson, A. G. (2014). Identifying the causes of pharmacoresistant epilepsy through a genome-wide association study with pathway and network analysis: from complexity to coherence to centrality. In JOURNAL OF NEUROLOGY Vol. 261 (pp. S484-S485). Retrieved from https://www.webofscience.com/

Conference Paper

Identifying the causes of pharmacoresistant epilepsy through a genome-wide association study with pathway and network analysis: from complexity to coherence to centrality

Mirza, N., Sills, G., Jorgensen, A., Johnson, M., Pirmohamed, M., & Marson, A. G. (2014). Identifying the causes of pharmacoresistant epilepsy through a genome-wide association study with pathway and network analysis: from complexity to coherence to centrality. In EUROPEAN JOURNAL OF NEUROLOGY Vol. 21 (pp. 755). Retrieved from https://www.webofscience.com/

Conference Paper

Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children

McWilliam, S. J., Antoine, D. J., Sabbisetti, V., Pearce, R. E., Jorgensen, A. L., Lin, Y., . . . Pirmohamed, M. (2014). Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children. Biomarker Medicine.

Journal article

2013

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Pirmohamed, M., Burnside, G., Eriksson, N., Jorgensen, A. L., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial of Genotype-Guided Dosing of Warfarin. New England Journal of Medicine, 369(24), 2294-2303. doi:10.1056/nejmoa1311386

DOI
10.1056/nejmoa1311386
Journal article

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Pirmohamed, M., Burnside, G., Eriksson, N., Jorgensen, A. L., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial of Genotype-Guided Dosing of Warfarin. NEW ENGLAND JOURNAL OF MEDICINE, 369(24), 2294-2303. doi:10.1056/NEJMoa1311386

DOI
10.1056/NEJMoa1311386
Journal article

<i>SLCO1B1</i> Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink

Carr, D. F., O'Meara, H., Jorgensen, A. L., Campbell, J., Hobbs, M., McCann, G., . . . Pirmohamed, M. (2013). <i>SLCO1B1</i> Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink. CLINICAL PHARMACOLOGY & THERAPEUTICS, 94(6), 695-701. doi:10.1038/clpt.2013.161

DOI
10.1038/clpt.2013.161
Journal article

Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population

Carr, D. F., Chaponda, M., Jorgensen, A. L., Castro, E. C., van Oosterhout, J. J., Khoo, S. H., . . . Pirmohamed, M. (2013). Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population. CLINICAL INFECTIOUS DISEASES, 56(9), 1330-1339. doi:10.1093/cid/cit021

DOI
10.1093/cid/cit021
Journal article

<i>CYP2C19*17</i> Gain-of-Function Polymorphism Is Associated With Peptic Ulcer Disease

Musumba, C. O., Jorgensen, A., Sutton, L., Van Eker, D., Zhang, E., O'Hara, N., . . . Pirmohamed, M. (2013). <i>CYP2C19*17</i> Gain-of-Function Polymorphism Is Associated With Peptic Ulcer Disease. CLINICAL PHARMACOLOGY & THERAPEUTICS, 93(2), 195-203. doi:10.1038/clpt.2012.215

DOI
10.1038/clpt.2012.215
Journal article

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia. BLOOD, 121(4), 628-637. doi:10.1182/blood-2012-01-405035

DOI
10.1182/blood-2012-01-405035
Journal article

A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study

Pirmohamed, M., Burnside, G., Stoddern, J., Prince, C., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study. CIRCULATION, 128(24), 2710-2711. Retrieved from https://www.webofscience.com/

Journal article

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Pirmohamed, M., Burnside, G., Eriksson, N., Jorgensen, A. L., Toh, C. H., Nicholson, T., & al., E. (2013). A Randomized Trial of Genotype-Guided Dosing of Warfarin. New England Journal of Medicine, (369), 2294-2303.

Journal article

A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.

Speed, D., Hoggart, C., Petrovski, S., Tachmazidou, I., Coffey, A., Jorgensen, A., . . . Johnson, M. R. (2013). A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.. Human Molecular Genetics.

Journal article

Adherence and variability in warfarin dose requirements: assessment in a prospective cohort

Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M., & Williamson, P. R. (2013). Adherence and variability in warfarin dose requirements: assessment in a prospective cohort. PHARMACOGENOMICS, 14(2), 151-163. doi:10.2217/PGS.12.199

DOI
10.2217/PGS.12.199
Journal article

Adherence and variability in warfarin dose requirements: assessment in a prospective cohort.

Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M., & Williamson, P. R. (2013). Adherence and variability in warfarin dose requirements: assessment in a prospective cohort..

Journal article

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population.

Carr, D. F., Chaponda, M., Jorgensen, A. L., Castro, E. C., van Oosterhout, J. J., Khoo, S. H., . . . Pirmohamed, M. (2013). Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population..

Journal article

Institutional profile: the Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK.

Alfirevic, A., Carr, D. F., Miyajima, F., Pushpakom, S., Sutton, L., Jorgensen, A. L., & Pirmohamed, M. (2013). Institutional profile: the Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK..

Journal article

SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink

Carr, D. F., O'Meara, H., Jorgensen, A. L., Campbell, J., Hobbs, M., McCann, G., . . . Pirmohamed, M. (2013). SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink. Clinical Pharmacology and Therapeutics, 94(6), 695-701. doi:10.1038/clpt.2013

DOI
10.1038/clpt.2013
Journal article

Systematic review of pharmacogenomics in psoriasis

Foulkes, A. C., Jorgensen, A., Pirmohamed, M., Griffiths, C. E., & Warren, R. B. (2013). Systematic review of pharmacogenomics in psoriasis. In JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 133 (pp. S88). Retrieved from https://www.webofscience.com/

Conference Paper

The Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK

Alfirevic, A., Carr, D. F., Miyajima, F., Pushpakom, S., Sutton, L., Jorgensen, A. L., & Pirmohamed, M. (2013). The Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK. PHARMACOGENOMICS, 14(8), 861-867. doi:10.2217/PGS.13.73

DOI
10.2217/PGS.13.73
Journal article

The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia

Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia. Blood, 121, 628-637.

Journal article

2012

HLA Genotype and Carbamazepine-Induced Cutaneous Adverse Drug Reactions: A Systematic Review

Yip, V. L., Marson, A. G., Jorgensen, A. L., Pirmohamed, M., & Alfirevic, A. (2012). HLA Genotype and Carbamazepine-Induced Cutaneous Adverse Drug Reactions: A Systematic Review. CLINICAL PHARMACOLOGY & THERAPEUTICS, 92(6), 757-765. doi:10.1038/clpt.2012.189

DOI
10.1038/clpt.2012.189
Journal article

HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review.

Yip, V., Marson, T., Jorgensen, A., Pirmohamed, M., & Alfirevic, A. (2012). HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review.. Clinical Pharmacology and Therapeutics, 92(6), 757-765.

Journal article

VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN

Thompson, B., Hawcutt, D. B., Carr, D. F., Jorgensen, A. L., Smyth, R. L., & Pirmohamed, M. (2012). VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN. THORAX, 67, A17. doi:10.1136/thoraxjnl-2012-202678.037

DOI
10.1136/thoraxjnl-2012-202678.037
Journal article

Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis

Jorgensen, A. L., FitzGerald, R. J., Oyee, J., Pirmohamed, M., & Williamson, P. R. (2012). Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis. PLOS ONE, 7(8). doi:10.1371/journal.pone.0044064

DOI
10.1371/journal.pone.0044064
Journal article

CYP2C19*17 GAIN OF FUNCTION MUTATION IS ASSOCIATED WITH PEPTIC ULCER DISEASE

Musumba, C. O., Eker, D. V., Jorgensen, A., Pritchard, D. M., & Pirmohamed, M. (2012). CYP2C19*17 GAIN OF FUNCTION MUTATION IS ASSOCIATED WITH PEPTIC ULCER DISEASE. GUT, 61, A363. doi:10.1136/gutjnl-2012-302514d.165

DOI
10.1136/gutjnl-2012-302514d.165
Journal article

Su1780 CYP2C19*17 Gain of Function Mutation is Associated With the Development of Peptic Ulcer Disease

Musumba, C. O., Van Eker, D., Jorgensen, A. L., Zhang, E., O'Hara, N., Pritchard, M., & Pirmohamed, M. (2012). Su1780 CYP2C19*17 Gain of Function Mutation is Associated With the Development of Peptic Ulcer Disease. Gastroenterology, 142(5), S-502. doi:10.1016/s0016-5085(12)61922-2

DOI
10.1016/s0016-5085(12)61922-2
Journal article

Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy

Alfirevic, Z., Stampalija, T., Roberts, D., & Jorgensen, A. L. (2012). Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (4). doi:10.1002/14651858.CD008991.pub2

DOI
10.1002/14651858.CD008991.pub2
Journal article

Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy

Horne, B. D., Lenzini, P. A., Wadelius, M., Jorgensen, A. L., Kimmel, S. E., Ridker, P. M., . . . Gage, B. F. (2012). Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy. THROMBOSIS AND HAEMOSTASIS, 107(2), 232-240. doi:10.1160/TH11-06-0388

DOI
10.1160/TH11-06-0388
Journal article

CYP2C19*17 Gain of Function Mutation is Associated With the Development of Peptic Ulcer Disease

Musumba, C. O., Van Eker, D., Jorgensen, A. L., Zhang, E., O'Hara, N., Pritchard, M., & Pirmohamed, M. (2012). CYP2C19*17 Gain of Function Mutation is Associated With the Development of Peptic Ulcer Disease. In GASTROENTEROLOGY Vol. 142 (pp. S502). Retrieved from https://www.webofscience.com/

Conference Paper

HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review

Yip, V. L., Marson, A. G., Jorgensen, A. L., Pirmohamed, M., & Alfirevic, A. (2012). HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review. Clinical Pharmacology and Therapeutics, 92(6), 757-765.

Journal article

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., . . . Pirmohamed, M. (2012). The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 73(1), 66-76. doi:10.1111/j.1365-2125.2011.04051.x

DOI
10.1111/j.1365-2125.2011.04051.x
Journal article

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., . . . Pirmohamed, M. (2012). The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors. British Journal of Clinical Pharmacology.

Journal article

The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hosiptal in the UK between 2005 and 2010

Musumba, C., Jorgensen, A., Sutton, L., Van Eker, D., Moorcroft, J., Hopkins, M., . . . Pirmohamed, M. (2012). The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hosiptal in the UK between 2005 and 2010. Alimentary Pharmacology and Therapeutics, 36(1), 48-56.

Journal article

The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hospital in the UK between 2005 and 2010

Musumba, C., Jorgensen, A., Sutton, L., Van Eker, D., Moorcroft, J., Hopkins, M., . . . Pirmohamed, M. (2012). The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hospital in the UK between 2005 and 2010. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 36(1), 48-56. doi:10.1111/j.1365-2036.2012.05118.x

DOI
10.1111/j.1365-2036.2012.05118.x
Journal article

2011

A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy

Avery, P. J., Jorgensen, A., Hamberg, A., Wadelius, M., Pirmohamed, M., & Kamali, F. (2011). A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy. CLINICAL PHARMACOLOGY & THERAPEUTICS, 90(5), 701-706. doi:10.1038/clpt.2011.186

DOI
10.1038/clpt.2011.186
Journal article

Changing Trends in Peptic Ulcer Disease: The Rise of NSAID-Induced and Fall of Helicobacter pylori -Induced Ulcers

Musumba, C. O., Van Eker, D., Jorgensen, A., Pritchard, M., & Pirmohamed, M. (2011). Changing Trends in Peptic Ulcer Disease: The Rise of NSAID-Induced and Fall of Helicobacter pylori -Induced Ulcers. Gastroenterology, 140(5), S-176. doi:10.1016/s0016-5085(11)60711-7

DOI
10.1016/s0016-5085(11)60711-7
Journal article

CHANGING TRENDS IN PEPTIC ULCER DISEASE: THE RISE OF NSAID-INDUCED AND FALL OF <i>H PYLORI</i>-INDUCED ULCERS

Musumba, C. O., Van Eker, D., Jorgensen, A., Pritchard, M., & Pirmohamed, M. (2011). CHANGING TRENDS IN PEPTIC ULCER DISEASE: THE RISE OF NSAID-INDUCED AND FALL OF <i>H PYLORI</i>-INDUCED ULCERS. In GUT Vol. 60. doi:10.1136/gut.2011.239301.219

DOI
10.1136/gut.2011.239301.219
Conference Paper

Risk modeling strategies for pharmacogenetic studies

Jorgensen, A. L., & Pirmohamed, M. (2011). Risk modeling strategies for pharmacogenetic studies. PHARMACOGENOMICS, 12(3), 397-410. doi:10.2217/PGS.10.198

DOI
10.2217/PGS.10.198
Journal article

Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy

Alfirevic, Z., Stampalija, T., Roberts, D., & Jorgensen, A. L. (n.d.). Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. In Z. Alfirevic (Ed.). John Wiley & Sons, Ltd. doi:10.1002/14651858.cd008991

DOI
10.1002/14651858.cd008991
Chapter

Changing Trends in Peptic Ulcer Disease: The Rise of NSAID-Induced and Fall of <i>Helicobacter pylori</i>-Induced Ulcers

Musumba, C. O., Van Eker, D., Jorgensen, A., Pritchard, M., & Pirmoltamed, M. (2011). Changing Trends in Peptic Ulcer Disease: The Rise of NSAID-Induced and Fall of <i>Helicobacter pylori</i>-Induced Ulcers. In GASTROENTEROLOGY Vol. 140 (pp. S176). Retrieved from https://www.webofscience.com/

Conference Paper

Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses

Fleeman, N., Dundar, Y., Dickson, R., Jorgensen, A., Pushpakom, S., McLeod, C., . . . Walley, T. (2011). Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses. PHARMACOGENOMICS JOURNAL, 11(1), 1-14. doi:10.1038/tpj.2010.73

DOI
10.1038/tpj.2010.73
Journal article

Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors

Mirza, N. S., Alfirevic, A., Jorgensen, A., Marson, A. G., & Pirmohamed, M. (2011). Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors. PHARMACOGENETICS AND GENOMICS, 21(5), 297-302. doi:10.1097/FPC.0b013e3283441b95

DOI
10.1097/FPC.0b013e3283441b95
Journal article

2010

Warfarin pharmacogenetics: a single <i>VKORC1</i> polymorphism is predictive of dose across 3 racial groups

Limdi, N. A., Wadelius, M., Cavallari, L., Eriksson, N., Crawford, D. C., Lee, M. -T. M., . . . Wagner, M. J. (2010). Warfarin pharmacogenetics: a single <i>VKORC1</i> polymorphism is predictive of dose across 3 racial groups. BLOOD, 115(18), 3827-3834. doi:10.1182/blood-2009-12-255992

DOI
10.1182/blood-2009-12-255992
Journal article

Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing

Lenzini, P., Wadelius, M., Kimmel, S., Anderson, J. L., Jorgensen, A. L., Pirmohamed, M., . . . Gage, B. F. (2010). Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing. CLINICAL PHARMACOLOGY & THERAPEUTICS, 87(5), 572-578. doi:10.1038/clpt.2010.13

DOI
10.1038/clpt.2010.13
Journal article

WARFARIN DOSING ALGORITHM REFINEMENTS AFTER 7-9 DAYS OF THERAPY BASED ON PHARMACOGENETIC, PHARMACOKINETIC, CLINICAL, AND LABORATORY DATA

Horne, B. D., Lenzini, P. A., Wadelius, M., Jorgensen, A. L., Kimmel, S. E., Eriksson, N., . . . Gage, B. F. (2010). WARFARIN DOSING ALGORITHM REFINEMENTS AFTER 7-9 DAYS OF THERAPY BASED ON PHARMACOGENETIC, PHARMACOKINETIC, CLINICAL, AND LABORATORY DATA. Journal of the American College of Cardiology, 55(10), A130.E1218. doi:10.1016/s0735-1097(10)61219-3

DOI
10.1016/s0735-1097(10)61219-3
Journal article

CYP4F2 genotype-phenotype correlation in human liver

Zhang, J. E., Jorgensen, A., Kline, K., Alfirevic, A., Zanger, U., & Pirmohamed, M. (2010). CYP4F2 genotype-phenotype correlation in human liver. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 70 (pp. 297-298). Retrieved from https://www.webofscience.com/

Conference Paper

Carbamazepine-induced hypersensitivity in Caucasians and genetic variability in the major histocompatibility complex

Alfirevic, A., Bourgeois, S., Jorgensen, A., Steen, K., Weetman, D., Park, B. K., . . . Pirmohamed, M. (2010). Carbamazepine-induced hypersensitivity in Caucasians and genetic variability in the major histocompatibility complex. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 70 (pp. 298). Retrieved from https://www.webofscience.com/

Conference Paper

Integration of genetic, clinical, and INR data to refine warfarin dosing

Lenzini, P., Wadelius, M., Kimmel, S., Anderson, J. L., Jorgensen, A. L., Pirmohamed, M., & al., E. (2010). Integration of genetic, clinical, and INR data to refine warfarin dosing. Unknown Journal, 87(5), 572-578.

Journal article

Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.

Mirza, N. S., Alfirevic, A., Jorgensen, A., Marson, A. G., & Pirmohamed, M. (2010). Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.. Pharmacogenetics and Genomics, 21(5), 297-302.

Journal article

Proposal of a pharmacogenetic-based dosing algorithm for the induction of warfarin anticoagulation therapy in patients with thromboembolic disease

Avery, P., Pirmohamed, M., Jorgensen, A., & Kamali, F. (2010). Proposal of a pharmacogenetic-based dosing algorithm for the induction of warfarin anticoagulation therapy in patients with thromboembolic disease. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 70 (pp. 291). Retrieved from https://www.webofscience.com/

Conference Paper

The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation

Fleeman, N., McLeod, C., Bagust, A., Beale, S., Boland, A., Dundar, Y., . . . Dickson, R. (2010). The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluation. HEALTH TECHNOLOGY ASSESSMENT, 14(3), 1-+. doi:10.3310/hta14030

DOI
10.3310/hta14030
Journal article

2009

Effects of <i>CYP4F2</i> genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy

Zhang, J. E., Jorgensen, A. L., Alfirevic, A., Williamson, P. R., Toh, C. H., Park, B. K., & Pirmohamed, M. (2009). Effects of <i>CYP4F2</i> genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy. PHARMACOGENETICS AND GENOMICS, 19(10), 781-789. doi:10.1097/FPC.0b013e3283311347

DOI
10.1097/FPC.0b013e3283311347
Journal article

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study

Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., . . . Pirmohamed, M. (2009). Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study. PHARMACOGENETICS AND GENOMICS, 19(10), 800-812. doi:10.1097/FPC.0b013e3283317ab5

DOI
10.1097/FPC.0b013e3283317ab5
Journal article

IMPACT OF PHARMACOGENETICS ON THE COSTS OF MANAGING ADVERSE EVENTS WITH WARFARIN: A PROSPECTIVE ANALYSIS

Hughes, D. A., Al-Zubiedi, S., Hanson, A., Jorgensen, A., & Pirmohamed, M. (2009). IMPACT OF PHARMACOGENETICS ON THE COSTS OF MANAGING ADVERSE EVENTS WITH WARFARIN: A PROSPECTIVE ANALYSIS. VALUE IN HEALTH, 12(3), A3-A4. doi:10.1016/S1098-3015(10)73081-3

DOI
10.1016/S1098-3015(10)73081-3
Journal article

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

Klein, T. E., Altman, R. B., Eriksson, N., Gage, B. F., Kimmel, S. E., Lee, M. -T. M., . . . Shin, J. G. (2009). Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data. NEW ENGLAND JOURNAL OF MEDICINE, 360(8), 753-764. Retrieved from https://www.webofscience.com/

Journal article

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data (vol 360, pg 753, 2009)

Klein, T. E., Altman, R. B., Eriksson, N., Gage, B. F., Kimmel, S. E., Lee, M. T. M., . . . Shin, J. G. (2009). Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data (vol 360, pg 753, 2009). NEW ENGLAND JOURNAL OF MEDICINE, 361(16), 1613. Retrieved from https://www.webofscience.com/

Journal article

Systematic Review of Pharmacogenetic Warfarin Dosing

van Schie, R. M. F., Jorgensen, A. L., de Boer, A., & Maitland-van der Zee, A. -H. (2009). Systematic Review of Pharmacogenetic Warfarin Dosing. JOURNAL OF GENERAL INTERNAL MEDICINE, 24(10), 1171. doi:10.1007/s11606-009-1083-9

DOI
10.1007/s11606-009-1083-9
Journal article

2008

Methodological quality of pharmacogenetic studies: Issues of concern

Jorgensen, A. L., & Williamson, P. R. (2008). Methodological quality of pharmacogenetic studies: Issues of concern. STATISTICS IN MEDICINE, 27(30), 6547-6569. doi:10.1002/sim.3420

DOI
10.1002/sim.3420
Journal article

Pharmacogenetics and pharmacogenomics: adverse drug reactions.

Jorgensen, A., & Alfirevic, A. (2008). Pharmacogenetics and pharmacogenomics: adverse drug reactions.. Pharmacogenomics, 9(10), 1397-1401. doi:10.2217/14622416.9.10.1397

DOI
10.2217/14622416.9.10.1397
Journal article

Cervical Stitch (Cerclage) For Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis

Jorgensen, A. L., Alfirevic, Z., Tudur Smith, C., & Williamson, P. R. (2008). Cervical Stitch (Cerclage) For Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis. Obstetric Anesthesia Digest, 28(3), 149-150. doi:10.1097/01.aoa.0000326390.19993.0d

DOI
10.1097/01.aoa.0000326390.19993.0d
Journal article

A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers

Drakeley, A. J., Jorgensen, A., Sklavounos, J., Aust, T., Gazvani, R., Williamson, P., & Kingsland, C. R. (2008). A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers. HUMAN REPRODUCTION, 23(5), 1101-1106. doi:10.1093/humrep/den064

DOI
10.1093/humrep/den064
Journal article

Cervical stitch (cerclage) for preventing pregnancy loss: individual patient data meta-analysis - Author's reply

Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2008). Cervical stitch (cerclage) for preventing pregnancy loss: individual patient data meta-analysis - Author's reply. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 115(6), 798-799. doi:10.1111/j.1471-0528.2008.01689.x

DOI
10.1111/j.1471-0528.2008.01689.x
Journal article

Cervical Stitch (Cerclage) for Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis

Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2008). Cervical Stitch (Cerclage) for Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis. Obstetrical &amp; Gynecological Survey, 63(3), 135-136. doi:10.1097/01.ogx.0000305196.42050.6e

DOI
10.1097/01.ogx.0000305196.42050.6e
Journal article

Warfarin pharmacogenetics: ready for clinical implementation?

Jorgensen, A. L. (2008). Warfarin pharmacogenetics: ready for clinical implementation?. JOURNAL OF PHARMACY AND PHARMACOLOGY, 60, A66-A67. Retrieved from https://www.webofscience.com/

Journal article

2007

Cervical stitch (cerclage) for preventing pregnancy loss: Individual patient data meta-analysis

Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2007). Cervical stitch (cerclage) for preventing pregnancy loss: Individual patient data meta-analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 114(12), 1460-1476. doi:10.1111/j.1471-0528.2007.01515.x

DOI
10.1111/j.1471-0528.2007.01515.x
Journal article

The association between polymorphisms in <i>RLIP76</i> and drug response in epilepsy

Leschziner, G. D., Jorgensen, A. L., Andrews, T., Williamson, P. R., Marson, A. G., Coffey, A. J., . . . Pirmohamed, M. (2007). The association between polymorphisms in <i>RLIP76</i> and drug response in epilepsy. PHARMACOGENOMICS, 8(12), 1715-1722. doi:10.2217/14622416.8.12.1715

DOI
10.2217/14622416.8.12.1715
Journal article

2006

<i>HLA-B</i> locus in Caucasian patients with carbamazepine hypersensitivity

Alfirevic, A., Jorgensen, A. L., Williamson, P. R., Chadwick, D. W., Park, B. K., & Pirmohamed, M. (2006). <i>HLA-B</i> locus in Caucasian patients with carbamazepine hypersensitivity. PHARMACOGENOMICS, 7(6), 813-818. doi:10.2217/14622416.7.6.813

DOI
10.2217/14622416.7.6.813
Journal article

Clinical factors and <i>ABCB1</i> polymorphisms in prediction of antiepileptic drug response:: a prospective cohort study

Leschziner, G., Jorgensen, A. L., Andrew, T., Pirmohaomed, M., Williamson, P. R., Marson, A. G., . . . Johnson, M. R. (2006). Clinical factors and <i>ABCB1</i> polymorphisms in prediction of antiepileptic drug response:: a prospective cohort study. LANCET NEUROLOGY, 5(8), 668-676. doi:10.1016/S1474-4422(06)70500-2

DOI
10.1016/S1474-4422(06)70500-2
Journal article

ABCB1 polymorphisms and haplotype previously associated with drug resistant epilepsy have no effect on therapeutic or adverse drug response in a large prospective epilepsy cohort

Leschziner, G., Jorgensen, A., Andrew, T., Middleditch, C., Pirmohamed, M., Williamson, P., . . . Johnson, M. R. (2006). ABCB1 polymorphisms and haplotype previously associated with drug resistant epilepsy have no effect on therapeutic or adverse drug response in a large prospective epilepsy cohort. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 77 (pp. 1394). Retrieved from https://www.webofscience.com/

Conference Paper

ACB1 polymorphisms and haplotype previously associated with drug-resistant epilepsy have no effect on therapeutic or adverse drug response in a large prospective cohort

Leschziner, G. D., Jorgensen, A., Andrew, T., Middleditch, C., Pirmohamed, M., Marson, T., . . . Johnson, M. R. (2006). ACB1 polymorphisms and haplotype previously associated with drug-resistant epilepsy have no effect on therapeutic or adverse drug response in a large prospective cohort. In DRUG METABOLISM REVIEWS Vol. 38 (pp. 84). Retrieved from https://www.webofscience.com/

Conference Paper

2005