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Some recent papers from the Human Bone Cell Research Group
.Bowler, W. B., C. J. Dixon, C. Halleux, R. Maier, G. Bilbe,
W. D. Fraser, J. A. Gallagher, and R. A. Hipskind.
(1999)
Signaling in
human osteoblasts by extracellular nucleotides - Their weak induction of the
c-fos proto-oncogene via Ca2+ mobilization is strongly potentiated by a
parathyroid hormone/cAMP-dependent protein kinase pathway independently of
mitogen-activated protein kinase. Journal of Biological Chemistry.
274: 14315-14324.
summary
W.B. Bowler, A .Littlewood-Evans, G. Bilbe, J.A Gallagher and C.J. Dixon
(1998). P2Y2 receptors are expressed by human osteoclasts of giant cell tumour
but do not mediate ATP-induced bone resorption.
Bone 22:195-200 summary
G.R. Sharpe, J.P. Dillon, J.A. Gallagher and W.D. Fraser (1998)
Human keratinocytes express transcripts for three isoforms of
parathyroid hormone-related protein (PTHrP), but not for the
parathyroid hormone/PTHrP receptor: effects of 1,25(OH)(2), vitamin
D-3. British Journal of Dermatology
138: 944-951
summary
LittlewoodEvans AJ, Bilbe G, Bowler WB, Farley D, Wlodarski B,
Kokubo T, Inaoka T, Sloane J, Evans DB, Gallagher JA (1997)
The osteoclast-associated protease cathepsin K is expressed in human
breast carcinoma
Cancer Research 57:5386-5390.
summary
Dixon CJ, Bowler WB, Walsh CA, Gallagher JA (1997)
Effects of extracellular nucleotides on single cells and populations of
human osteoblasts: Contribution of cell heterogeneity to relative potencies.
British Journal of Pharmacology 120:777-780.
summary
LittlewoodEvans A, Kokubo T, Ishibashi O, Inaoka T, Wlodarski B,
Gallagher JA, Bilbe G (1997)
Localization of cathepsin K in human osteoclasts by in situ hybridization
and immunohistochemistry. Bone 20:81-86.
summary
Dixon CJ, Bowler WB, Fleetwood P, Ginty AF, Gallagher JA, Carron JA (1997)
Extracellular nucleotides stimulate proliferation in MCF-7 breast cancer
cells via P-2-purinoceptors. Brit. J. Cancer 75:34-39.
summary
Carron JA, Fraser WD, Gallagher JA (1997)
Co-expression of PTHrP and
the PTH/PTHrP receptor in human breast and colon tumours. Brit. J. Cancer 76:
1095-1098 summary
Walsh CA, Bowler WB, Bilbe G, Fraser WD, Gallagher JA (1997)
Effects of PTH on PTHrP gene expression in human osteoblasts: Up-regulation
with the kinetics of an immediate early gene. Biochemical and Biophysical
Research Communications 239: 155-158
summary
others
Birch MA, Carron JA, Scott M, Fraser WD, Gallagher JA (1995) Parathyroid
hormone (PTH)/PTH-Related Protein (PTHrP) Receptor Expression and Mitogenic
Responses In Human Breast Cancer Cell Lines. British Journal of Cancer
72:90-95.
summary
Walsh CA, Birch MA, Fraser WD, Lawton R, Dorgan J, Walsh S, Sansom D,
Beresford JN, Gallagher JA (1995)
Expression and Secretion Of Parathyroid Hormone-Related Protein By Human
Bone-Derived Cells In Vitro - Effects Of Glucocorticoids. Journal of Bone
and Mineral Research
10:17-25.summary
Bowler WB, Birch MA, Gallagher JA, Bilbe G (1995) Identification and Cloning Of
Human P-2U Purinoceptor Present In Osteoclastoma, Bone, and Osteoblasts.
Journal of Bone and Mineral Research 10:
1137-1145.summary
Carron JA, Walsh CA, Fraser WD, Gallagher JA (1995) Thrombospondin Promotes
Resorption By Osteoclasts in vitro. Biochemical and Biophysical Research
Communications 213:1017-1025.summary