2022
Salt-inducible kinase 2 regulates fibrosis during bleomycin- induced lung injury (Journal article)
van Gijsel-Bonnello, M., Darling, N. J., Tanaka, T., Di Carmine, S., Marchesi, F., Thomson, S., . . . Arthur, J. S. C. (2022). Salt-inducible kinase 2 regulates fibrosis during bleomycin- induced lung injury. JOURNAL OF BIOLOGICAL CHEMISTRY, 298(12). doi:10.1016/j.jbc.2022.102644DOI: 10.1016/j.jbc.2022.102644
2021
Salt inducible kinases 2 and 3 are required for thymic T cell development (Journal article)
Nefla, M., Darling, N. J., Bonnello, M. V. G., Cohen, P., & Arthur, J. S. C. (2021). Salt inducible kinases 2 and 3 are required for thymic T cell development. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-00986-0DOI: 10.1038/s41598-021-00986-0
A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases (Journal article)
Mokhtar, A. M. B. A., Ahmed, S. B. M., Darling, N. J., Harris, M., Mott, H. R., & Owen, D. (2021). A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases. BIOCHEMISTRY, 60(19), 1533-1551. doi:10.1021/acs.biochem.1c00120DOI: 10.1021/acs.biochem.1c00120
Nuts and bolts of the salt-inducible kinases (SIKs) (Journal article)
Darling, N. J., & Cohen, P. (2021). Nuts and bolts of the salt-inducible kinases (SIKs). BIOCHEMICAL JOURNAL, 478(7), 1377-1397. doi:10.1042/BCJ20200502DOI: 10.1042/BCJ20200502
Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells (Journal article)
Darling, N. J., Arthur, J. S. C., & Cohen, P. (2021). Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 296. doi:10.1016/j.jbc.2021.100428DOI: 10.1016/j.jbc.2021.100428
2020
Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses (Journal article)
Hutchinson, L. D., Darling, N. J., Nicolaou, S., Gori, I., Squair, D. R., Cohen, P., . . . Sapkota, G. P. (2020). Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses. CELL DEATH & DISEASE, 11(1). doi:10.1038/s41419-020-2241-6DOI: 10.1038/s41419-020-2241-6
2017
ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death (Journal article)
Darling, N. J., Balmanno, K., & Cook, S. J. (2017). ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death. PLOS ONE, 12(9). doi:10.1371/journal.pone.0184907DOI: 10.1371/journal.pone.0184907
Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages (Journal article)
Darling, N. J., Toth, R., Arthur, J. S. C., & Clark, K. (2017). Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages. BIOCHEMICAL JOURNAL, 474, 521-537. doi:10.1042/BCJ20160646DOI: 10.1042/BCJ20160646
2014
The role of MAPK signalling pathways in the response to endoplasmic reticulum stress (Journal article)
Darling, N. J., & Cook, S. J. (2014). The role of MAPK signalling pathways in the response to endoplasmic reticulum stress. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1843(10), 2150-2163. doi:10.1016/j.bbamcr.2014.01.009DOI: 10.1016/j.bbamcr.2014.01.009
