Publications
2024
Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson’s disease progression
Fröhlich, A., Pfaff, A. L., Middlehurst, B., Hughes, L. S., Bubb, V. J., Quinn, J. P., & Koks, S. (n.d.). Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson’s disease progression. Scientific Reports, 14(1). doi:10.1038/s41598-024-61753-5
Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expressions in the Central Nervous System.
Hughes, L. S., Fröhlich, A., Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Kõks, S. (2024). Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expressions in the Central Nervous System.. Biomolecules, 14(3), 358. doi:10.3390/biom14030358
A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models.
Hall, A., Middlehurst, B., Cadogan, M. A. M., Reed, X., Billingsley, K. J., Bubb, V. J., & Quinn, J. P. (2024). A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models.. Scientific reports, 14(1), 792. doi:10.1038/s41598-023-50307-w
2023
Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expression in the Central Nervous System
Regulation of expression quantitative trait loci by SVA retrotransposons within the major histocompatibility complex.
Kulski, J. K., Pfaff, A. L., Marney, L. D., Fröhlich, A., Bubb, V. J., Quinn, J. P., & Koks, S. (2023). Regulation of expression quantitative trait loci by SVA retrotransposons within the major histocompatibility complex.. Experimental biology and medicine (Maywood, N.J.), 248(23), 2304-2318. doi:10.1177/15353702231209411
Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals.
Fröhlich, A., Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2023). Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals.. Experimental biology and medicine (Maywood, N.J.), 15353702231209427. doi:10.1177/15353702231209427
Reference LINE-1 insertion polymorphisms correlate with Parkinson's disease progression and differential transcript expression in the PPMI cohort.
Fröhlich, A., Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2023). Reference LINE-1 insertion polymorphisms correlate with Parkinson's disease progression and differential transcript expression in the PPMI cohort.. Scientific reports, 13(1), 13857. doi:10.1038/s41598-023-41052-1
A Genome-Wide Screen for the Exonisation of Reference SINE-VNTR-Alus and Their Expression in CNS Tissues of Individuals with Amyotrophic Lateral Sclerosis
Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2023). A Genome-Wide Screen for the Exonisation of Reference SINE-VNTR-Alus and Their Expression in CNS Tissues of Individuals with Amyotrophic Lateral Sclerosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(14). doi:10.3390/ijms241411548
Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson’s disease progression
Genome-Wide Analysis of Structural Variants in Parkinson Disease
Billingsley, K. J., Ding, J., Jerez, P. A., Illarionova, A., Levine, K., Grenn, F. P., . . . Singleton, A. (2023). Genome-Wide Analysis of Structural Variants in Parkinson Disease. ANNALS OF NEUROLOGY. doi:10.1002/ana.26608
CRISPR deletion of a SINE-VNTR-<i>Alu</i> (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the <i>MAPT</i> locus.
Fröhlich, A., Hughes, L. S., Middlehurst, B., Pfaff, A. L., Bubb, V. J., Koks, S., & Quinn, J. P. (2023). CRISPR deletion of a SINE-VNTR-<i>Alu</i> (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the <i>MAPT</i> locus.. Frontiers in neurology, 14, 1273036. doi:10.3389/fneur.2023.1273036
2022
Characterisation of retrotransposon insertion polymorphisms in whole genome sequencing data from individuals with amyotrophic lateral sclerosis
Savage, A. L., Iacoangeli, A., Schumann, G. G., Rubio-Roldan, A., Garcia-Perez, J. L., Al Khleifat, A., . . . Quinn, J. P. (2022). Characterisation of retrotransposon insertion polymorphisms in whole genome sequencing data from individuals with amyotrophic lateral sclerosis. GENE, 843. doi:10.1016/j.gene.2022.146799
A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene <i>CFAP410</i> correlates with differential isoform expression.
Marshall, J. N. G., Fröhlich, A., Li, L., Pfaff, A. L., Middlehurst, B., Spargo, T. P., . . . Quinn, J. P. (2022). A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene <i>CFAP410</i> correlates with differential isoform expression.. Frontiers in molecular neuroscience, 15, 954928. doi:10.3389/fnmol.2022.954928
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson's disease
Koks, S., Pfaff, A. L., Singleton, L. M., Bubb, V. J., & Quinn, J. P. (2022). Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson's disease. EXPERIMENTAL BIOLOGY AND MEDICINE, 247(18), 1680-1690. doi:10.1177/15353702221117147
Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis
Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2022). Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis. MOLECULAR BRAIN, 15(1). doi:10.1186/s13041-022-00914-x
Longitudinal intronic RNA-Seq analysis of Parkinson's disease patients reveals disease-specific nascent transcription.
Koks, S., Pfaff, A. L., Bubb, V. J., & Quinn, J. P. (2022). Longitudinal intronic RNA-Seq analysis of Parkinson's disease patients reveals disease-specific nascent transcription.. Experimental biology and medicine (Maywood, N.J.), 15353702221081027. doi:10.1177/15353702221081027
Characterisation of the Function of a SINE-VNTR-<i>Alu</i> Retrotransposon to Modulate Isoform Expression at the <i>MAPT</i> Locus
Frohlich, A., Pfaff, A. L., Bubb, V. J., Koks, S., & Quinn, J. P. (2022). Characterisation of the Function of a SINE-VNTR-<i>Alu</i> Retrotransposon to Modulate Isoform Expression at the <i>MAPT</i> Locus. FRONTIERS IN MOLECULAR NEUROSCIENCE, 15. doi:10.3389/fnmol.2022.815695
Analysis of the Retrotransposon SINE-VNTR-Alu (SVA) Polymorphisms in the Genetics and Pathophysiology of Complex Diseases
Kõks, S., Singleton, L. M., Quinn, J. P., Bubb, V. J., & Pfaff, A. L. (2022). Analysis of the Retrotransposon SINE-VNTR-Alu (SVA) Polymorphisms in the Genetics and Pathophysiology of Complex Diseases. In Neuromethods (pp. 63-77). Springer US. doi:10.1007/978-1-0716-2357-2_4
2021
Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome.
Storm, C. S., Kia, D. A., Almramhi, M. M., Bandres-Ciga, S., Finan, C., International Parkinson’s Disease Genomics Consortium (IPDGC)., . . . Wood, N. W. (2021). Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome.. Nature communications, 12(1), 7342. doi:10.1038/s41467-021-26280-1
Characterisation of the Function of a SINE-VNTR-Alu Retrotransposon to Modulate Isoform Expression at the MAPT Locus
Longitudinal intronic RNA-Seq analysis of Parkinson’s Disease patients reveals disease-specific nascent transcription
Kõks, S., Pfaff, A., Bubb, V., & Quinn, J. (2021). Longitudinal intronic RNA-Seq analysis of Parkinson’s Disease patients reveals disease-specific nascent transcription. doi:10.1101/2021.11.03.21265851
Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease.
Blauwendraat, C., Iwaki, H., Makarious, M. B., Bandres-Ciga, S., Leonard, H. L., Grenn, F. P., . . . International Parkinson's Disease Genomics Consortium (IPDGC). (2021). Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease.. Annals of neurology, 90(1), 35-42. doi:10.1002/ana.26090
Identification of sixteen novel candidate genes for late onset Parkinson's disease.
Gialluisi, A., Reccia, M. G., Modugno, N., Nutile, T., Lombardi, A., Di Giovannantonio, L. G., . . . Esposito, T. (2021). Identification of sixteen novel candidate genes for late onset Parkinson's disease.. Molecular neurodegeneration, 16(1), 35. doi:10.1186/s13024-021-00455-2
Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome
Koks, S., Pfaff, A. L., Bubb, V. J., & Quinn, J. P. (2021). Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(12). doi:10.3390/ijms22126319
Variable number tandem repeats - Their emerging role in sickness and health
Marshall, J. N. G., Lopez, A. I., Pfaff, A. L., Koks, S., Quinn, J. P., & Bubb, V. J. (2021). Variable number tandem repeats - Their emerging role in sickness and health. EXPERIMENTAL BIOLOGY AND MEDICINE, 246(12), 1368-1376. doi:10.1177/15353702211003511
Reference SVA insertion polymorphisms are associated with Parkinson's Disease progression and differential gene expression
Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2021). Reference SVA insertion polymorphisms are associated with Parkinson's Disease progression and differential gene expression. NPJ PARKINSONS DISEASE, 7(1). doi:10.1038/s41531-021-00189-4
Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes
Koks, S., Pfaff, A. L., Bubb, V. J., & Quinn, J. P. (2021). Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes. GENES, 12(3). doi:10.3390/genes12030423
CRISPR Deletion of a SVA Retrotransposon Demonstrates Function as a <i>cis</i>-Regulatory Element at the <i>TRPV1/TRPV3</i> Intergenic Region
Price, E., Gianfrancesco, O., Harrison, P. T., Frank, B., Bubb, V. J., & Quinn, J. P. (2021). CRISPR Deletion of a SVA Retrotransposon Demonstrates Function as a <i>cis</i>-Regulatory Element at the <i>TRPV1/TRPV3</i> Intergenic Region. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(4). doi:10.3390/ijms22041911
At the dawn of the transcriptomic medicine
Koks, G., Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2021). At the dawn of the transcriptomic medicine. EXPERIMENTAL BIOLOGY AND MEDICINE, 246(3), 286-292. doi:10.1177/1535370220954788
Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the Apoe and Mapt Haplotypes
Koks, S., Pfaff, A., Bubb, V., & Quinn, J. (2021). Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the Apoe and Mapt Haplotypes. doi:10.20944/preprints202101.0149.v1
2020
Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis
Savage, A. L., Lopez, A. I., Iacoangeli, A., Bubb, V. J., Smith, B., Troakes, C., . . . Quinn, J. P. (2020). Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis. MOLECULAR BRAIN, 13(1). doi:10.1186/s13041-020-00694-2
A SINE-VNTR-Alu in the LRIG2 Promoter Is Associated with Gene Expression at the Locus
Hall, A., Moore, A. K., Hernandez, D. G., Billingsley, K. J., Bubb, V. J., & Quinn, J. P. (n.d.). A SINE-VNTR-Alu in the LRIG2 Promoter Is Associated with Gene Expression at the Locus. International Journal of Molecular Sciences, 21(22), 8486. doi:10.3390/ijms21228486
POLYMORPHIC REFERENCE SVAS ARE ASSOCIATED WITH PARKINSON'S DISEASE PROGRESSION MARKERS AND DIFFERENTIAL GENE EXPRESSION IN THE PPMI COHORT
Pfaff, A., Bubb, V., Quinn, J., & Koks, S. (2020). POLYMORPHIC REFERENCE SVAS ARE ASSOCIATED WITH PARKINSON'S DISEASE PROGRESSION MARKERS AND DIFFERENTIAL GENE EXPRESSION IN THE PPMI COHORT. In PARKINSONISM & RELATED DISORDERS Vol. 79 (pp. E30). Retrieved from https://www.webofscience.com/
An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson's Disease Risk and Progression in the PPMI Cohort
Pfaff, A. L., Bubb, V. J., Quinn, J. P., & Koks, S. (2020). An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson's Disease Risk and Progression in the PPMI Cohort. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(18). doi:10.3390/ijms21186562
Reference SVA insertion polymorphisms are associated with dopaminergic degeneration in Parkinson’s Disease and differential gene expression in the PPMI cohort
Pfaff, A., Bubb, V., Quinn, J., & Koks, S. (2020). Reference SVA insertion polymorphisms are associated with dopaminergic degeneration in Parkinson’s Disease and differential gene expression in the PPMI cohort. doi:10.21203/rs.3.rs-41600/v1
Genetic interaction between two VNTRs in the MAOA gene is associated with the nicotine dependence
Koks, G., Prans, E., Ho, X. D., Duy, B. H., Tran, H. D. T., Ngo, N. B. T., . . . Koks, S. (2020). Genetic interaction between two VNTRs in the MAOA gene is associated with the nicotine dependence. EXPERIMENTAL BIOLOGY AND MEDICINE, 245(8), 733-739. doi:10.1177/1535370220916888
2019
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Nalls, M. A., Blauwendraat, C., Vallerga, C. L., Heilbron, K., Bandres-Ciga, S., Chang, D., . . . Zhang, F. (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 18(12), 1091-1102. doi:10.1016/s1474-4422(19)30320-5
The Role of SINE-VNTR-Alu (SVA) Retrotransposons in Shaping the Human Genome
Gianfrancesco, O., Geary, B., Savage, A. L., Billingsley, K. J., Bubb, V. J., & Quinn, J. P. (2019). The Role of SINE-VNTR-Alu (SVA) Retrotransposons in Shaping the Human Genome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(23). doi:10.3390/ijms20235977
Distinct chromatin structures at the monoamine oxidase-A promoter correlate with allele-specific expression in SH-SY5Y cells
Manca, M., Pessoa, V., Myers, P., Pickles, A., Hill, J., Sharp, H., . . . Quinn, J. P. (2019). Distinct chromatin structures at the monoamine oxidase-A promoter correlate with allele-specific expression in SH-SY5Y cells. GENES BRAIN AND BEHAVIOR, 18(6). doi:10.1111/gbb.12483
Non-coding genetic variation shaping mental health
Quinn, J. P., Savage, A. L., & Bubb, V. J. (2019). Non-coding genetic variation shaping mental health. CURRENT OPINION IN PSYCHOLOGY, 27, 18-24. doi:10.1016/j.copsyc.2018.07.006
Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset
Billingsley, K. J., Barbosa, I. A., Bandres-Ciga, S., Quinn, J. P., Bubb, V. J., Deshpande, C., . . . IPDGC. (2019). Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset. NPJ PARKINSONS DISEASE, 5. doi:10.1038/s41531-019-0080-x
Analysis of repetitive element expression in the blood and skin of patients with Parkinson’s disease identifies differential expression of satellite elements
Billingsley, K., Quinn, J., & Bubb, V. (2019). Analysis of repetitive element expression in the blood and skin of patients with Parkinson’s disease identifies differential expression of satellite elements. Scientific Reports, 9. doi:10.1038/s41598-019-40869-z
Retrotransposons in the development and progression of amyotrophic lateral sclerosis
Savage, A. L., Schumann, G., Breen, G., Bubb, V., Al-Chalabi, A., & Quinn, J. (2019). Retrotransposons in the development and progression of amyotrophic lateral sclerosis. Journal of Neurology Neurosurgery and Psychiatry, 90(3), 284-293. doi:10.1136/jnnp-2018-319210
Treating the “E” in “G × E”: Trauma-Informed Approaches and Psychological Therapy Interventions in Psychosis
Gianfrancesco, O., Bubb, V. J., & Quinn, J. P. (2019). Treating the “E” in “G × E”: Trauma-Informed Approaches and Psychological Therapy Interventions in Psychosis. Frontiers in Psychiatry. doi:10.3389/fpsyt.2019.00009
2018
Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology
Billingsley, K. J., Manca, M., Gianfrancesco, O., Collier, D., Sharp, H. M., Bubb, V. J., & Quinn, J. (2018). Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology. Schizophrenia Research, 199, 168-175. doi:10.1016/j.schres.2018.02.036
The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats
Manca, M., Pessoa, V., Lopez, A. I., Harrison, P. T., Miyajima, F., Sharp, H., . . . Quinn, J. P. (2018). The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats. JOURNAL OF MOLECULAR NEUROSCIENCE, 64(3), 459-470. doi:10.1007/s12031-018-1044-z
2017
SVA retrotransposons as potential modulators of neuropeptide gene expression
Gianfrancesco, O., Bubb, V. J., & Quinn, J. P. (2017). SVA retrotransposons as potential modulators of neuropeptide gene expression. NEUROPEPTIDES, 64, 3-7. doi:10.1016/j.npep.2016.09.006
Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus
Gianfrancesco, O., Warburton, A., Collier, D. A., Bubb, V. J., & Quinn, J. P. (2017). Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus. Schizophrenia Research, 184, 109-115. doi:10.1016/j.schres.2016.11.034
Potential impact of primate‐specific SVA retrotransposons during the evolution of human cognitive function.
Bubb, V. J., Quinn, J. P., Savage, A., Vasieva, O., Cetiner, S., & Schumann, G. G. (2017). Potential impact of primate‐specific SVA retrotransposons during the evolution of human cognitive function.. Trends in Evolutionary Biology. doi:10.4081/eb.2017.6514
2016
Identification and Potential Regulatory Properties of Evolutionary Conserved Regions (ECRs) at the Schizophrenia-Associated MIR137 Locus
Gianfrancesco, O., Griffiths, D., Myers, P., Collier, D. A., Bubb, V. J., & Quinn, J. P. (2016). Identification and Potential Regulatory Properties of Evolutionary Conserved Regions (ECRs) at the Schizophrenia-Associated MIR137 Locus. JOURNAL OF MOLECULAR NEUROSCIENCE, 60(2), 239-247. doi:10.1007/s12031-016-0812-x
A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression
Warburton, A., Breen, G., Bubb, V., & Quinn, J. (2016). A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression. Schizophrenia Bulletin, 42(4), 1003-1008. doi:10.1093/schbul/sbv144
A TOMM40 poly-T variant modulates gene expression and is associated with vocabulary ability and decline in nonpathologic aging
Payton, A., Sindrewicz, P., Pessoa, V., Platt, H., Horan, M., Ollier, W., . . . Quinn, J. P. (2016). A TOMM40 poly-T variant modulates gene expression and is associated with vocabulary ability and decline in nonpathologic aging. Neurobiology of Aging, 39. doi:10.1016/j.neurobiolaging.2015.11.017
2015
Characterization of a REST-Regulated Internal Promoter in the Schizophrenia Genome-Wide Associated Gene MIR137
Warburton, A., Breen, G., Rujescu, D., Bubb, V., & Quinn, J. (2015). Characterization of a REST-Regulated Internal Promoter in the Schizophrenia Genome-Wide Associated Gene MIR137. Schizophrenia Bulletin, 41(3), 698-707. doi:10.1093/schbul/sbu117
Molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF
Warburton, A., Savage, A. L., Myers, P., Peeney, D., Bubb, V. J., & Quinn, J. P. (2015). Molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF. JOURNAL OF AFFECTIVE DISORDERS, 172, 63-73. doi:10.1016/j.jad.2014.09.024
Characterisation of multiple regulatory domains spanning the major transcriptional start site of the FUS gene, a candidate gene for motor neurone disease
Khursheed, K., Wilm, T., Cashman, C., Quinn, J., Bubb, V., & Moss, D. (2015). Characterisation of multiple regulatory domains spanning the major transcriptional start site of the FUS gene, a candidate gene for motor neurone disease. Brain Research, 1595, 1-9. doi:10.1016/j.brainres.2014.10.056
2014
An Evaluation of a SVA Retrotransposon in the FUS Promoter as a Transcriptional Regulator and Its Association to ALS
Savage, A., Wilm, T., Khursheed, K., Shatunov, A., Morrison, K., Shaw, P., . . . Quinn, J. (2014). An Evaluation of a SVA Retrotransposon in the FUSPromoter as a Transcriptional Regulator and ItsAssociation to ALS. PLoS ONE, 9(6). doi:10.1371/journal.pone.0090833
SVA retrotransposons as modulators of gene expression.
Quinn, J. P., & Bubb, V. J. (2014). SVA retrotransposons as modulators of gene expression.. Mobile genetic elements, 4, e32102. doi:10.4161/mge.32102
2013
Polymorphic variation as a driver of differential neuropeptide gene expression
Quinn, J. P., Warburton, A., Myers, P., Savage, A. L., & Bubb, V. J. (2013). Polymorphic variation as a driver of differential neuropeptide gene expression. NEUROPEPTIDES, 47(6), 395-400. doi:10.1016/j.npep.2013.10.003
Allele-specific expression of the serotonin transporter and its transcription factors following lamotrigine treatment in vitro
D'Souza, U. M., Powell-Smith, G., Haddley, K., Powell, T. R., Bubb, V. J., Price, T., . . . Farmer, A. E. (2013). Allele-specific expression of the serotonin transporter and its transcription factors following lamotrigine treatment in vitro. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 162B(5), 474-483. doi:10.1002/ajmg.b.32178
Characterisation of the potential function of SVA retrotransposons to modulate gene expression patterns
Savage, A. L., Bubb, V. J., Breen, G., & Quinn, J. P. (2013). Characterisation of the potential function of SVA retrotransposons to modulate gene expression patterns. BMC EVOLUTIONARY BIOLOGY, 13. doi:10.1186/1471-2148-13-101
2012
CTCF and Sp1 interact with the Murine gammaherpesvirus 68 internal repeat elements
Stevens, H. C., Cham, K. S. -W., Hughes, D. J., Sun, R., Sample, J. T., Bubb, V. J., . . . Quinn, J. P. (2012). CTCF and Sp1 interact with the Murine gammaherpesvirus 68 internal repeat elements. VIRUS GENES, 45(2), 265-273. doi:10.1007/s11262-012-0769-y
Intronic Tandem Repeat in the Serotonin Transporter Gene in Old World Monkeys: a New Transcriptional Regulator?
Paredes, U. M., Bubb, V. J., Haddley, K., Macho, G. A., & Quinn, J. P. (2012). Intronic Tandem Repeat in the Serotonin Transporter Gene in Old World Monkeys: a New Transcriptional Regulator?. JOURNAL OF MOLECULAR NEUROSCIENCE, 47(2), 401-407. doi:10.1007/s12031-011-9664-6
Behavioural genetics of the serotonin transporter.
Haddley, K., Bubb, V. J., Breen, G., Parades-Esquivel, U. M., & Quinn, J. P. (2012). Behavioural genetics of the serotonin transporter.. Current topics in behavioral neurosciences, 12, 503-535. doi:10.1007/7854_2011_186
'Behavioural Genetics of the Serotonin Transporter'.
Haddley, K., Bubb, V. J., Breen, G., Parades-Esquivel, U. M., & Quinn, J. P. (2012). 'Behavioural Genetics of the Serotonin Transporter'.. Curr Top Behav Neurosci.
Activity-Dependent Neuroprotective Protein Modulates Its Own Gene Expression
Aboonq, M. S., Vasiliou, S. A., Haddley, K., Quinn, J. P., & Bubb, V. J. (2012). Activity-Dependent Neuroprotective Protein Modulates Its Own Gene Expression. JOURNAL OF MOLECULAR NEUROSCIENCE, 46(1), 33-39. doi:10.1007/s12031-011-9562-y
The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro
Vasiliou, S. A., Ali, F. R., Haddley, K., Cardoso, M. C., Bubb, V. J., & Quinn, J. P. (2012). The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro. ADDICTION BIOLOGY, 17(1), 156-170. doi:10.1111/j.1369-1600.2010.00288.x
2011
A long AAAG repeat allele in the 5′ UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells
Galindo, C. L., McCormick, J. F., Bubb, V. J., Alkadem, D. H. A., Li, L. -S., McIver, L. J., . . . Garner, H. R. (2011). A long AAAG repeat allele in the 5′ UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells. BREAST CANCER RESEARCH AND TREATMENT, 130(1), 41-48. doi:10.1007/s10549-010-1237-9
Lithium Chloride Regulation of the Substance P Encoding Preprotachykinin A, Tac1 Gene in Rat Hippocampal Primary Cells
Haddley, K., Spencer, E. M., Vasiliou, S. A., Howard, M., Thippeswamy, T., Bubb, V. J., & Quinn, J. P. (2011). Lithium Chloride Regulation of the Substance P Encoding Preprotachykinin A, Tac1 Gene in Rat Hippocampal Primary Cells. JOURNAL OF MOLECULAR NEUROSCIENCE, 45(2), 94-100. doi:10.1007/s12031-010-9431-0
Distinct Gene Expression Profiles Directed by the Isoforms of the Transcription Factor Neuron-Restrictive Silencer Factor in Human SK-N-AS Neuroblastoma Cells
Gillies, S. G., Haddley, K., Vasiliou, S. A., Jacobson, G. M., von Mentzer, B., Bubb, V. J., & Quinn, J. P. (2011). Distinct Gene Expression Profiles Directed by the Isoforms of the Transcription Factor Neuron-Restrictive Silencer Factor in Human SK-N-AS Neuroblastoma Cells. JOURNAL OF MOLECULAR NEUROSCIENCE, 44(2), 77-90. doi:10.1007/s12031-010-9420-3
An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex
Paredes, U. M., Bubb, V. J., Haddley, K., Macho, G. A., & Quinn, J. P. (2011). An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex. BMC NEUROSCIENCE, 12. doi:10.1186/1471-2202-12-46
Activity-Dependent Neuroprotective Protein Modulates Its Own Gene Expression.
Aboonq, M. S., Vasiliou, S. A., Haddley, K., Quinn, J. P., & Bubb, V. J. (2011). Activity-Dependent Neuroprotective Protein Modulates Its Own Gene Expression.. J Molecular Neuroscience.
An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex.
Paredes, U. M., Bubb, V. J., Haddley, K., Macho, G. A., & Quinn, J. P. (2011). An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex.. BMC Neuroscience, 12, 46.
Intronic Tandem Repeat in the Serotonin Transporter Gene in Old World Monkeys: a New Transcriptional Regulator?
Paredes, U. M., Bubb, V. J., Haddley, K., Macho, G. A., & Quinn, J. P. (2011). Intronic Tandem Repeat in the Serotonin Transporter Gene in Old World Monkeys: a New Transcriptional Regulator?. J Molecular Neuroscience.
The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro.
Vasiliou, S. A., Ali, F. R., Haddley, K., Cardoso, M. C., Bubb, V. J., & Quinn, J. P. (2011). The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro.. Addiction Biology.
2010
A long AAAG repeat allele in the 5' UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells.
Galindo, C. L., McCormick, J. F., Bubb, V. J., Abid Alkadem, D. H., Li, L. S., McIver, L. J., . . . Garner, H. R. (2010). A long AAAG repeat allele in the 5' UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells.. Breast Cancer Res Treat..
Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF
Ali, F. R., Vasiliou, S. A., Haddley, K., Paredes, U. M., Roberts, J. C., Miyajima, F., . . . Quinn, J. P. (2010). Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF. Journal of Neurochemistry, 112(1), 296-306. doi:10.1111/j.1471-4159.2009.06453.x
Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF
Ali, F. R., Vasiliou, S. A., Haddley, K., Paredes, U. M., Roberts, J. C., Miyajima, F., . . . Quinn, J. P. (2010). Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF. JOURNAL OF NEUROCHEMISTRY, 112(1), 296-306. doi:10.1111/j.1471-4159.2009.06453.x
Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF.
Ali, F. R., Vasiliou, S. A., Haddley, K., Paredes, U. M., Roberts, J. C., Miyajima, F., . . . Quinn, J. P. (2010). Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF.. J Neurochem, 112((1)), 296-306.
Distinct Gene Expression Profiles Directed by the Isoforms of the Transcription Factor Neuron-Restrictive Silencer Factor in Human SK-N-AS Neuroblastoma Cells.
Gillies, S. G., Haddley, K., Vasiliou, S. A., Jacobson, G. M., von Mentzer, B., Bubb, V. J., & Quinn, J. P. (2010). Distinct Gene Expression Profiles Directed by the Isoforms of the Transcription Factor Neuron-Restrictive Silencer Factor in Human SK-N-AS Neuroblastoma Cells.. J Mol Neurosci..
Lithium Chloride Regulation of the Substance P Encoding Preprotachykinin A, Tac1 Gene in Rat Hippocampal Primary Cells.
Haddley, K., Spencer, E. M., Vasiliou, S. A., Howard, M., Thippeswamy, T., Bubb, V. J., & Quinn, J. P. (2010). Lithium Chloride Regulation of the Substance P Encoding Preprotachykinin A, Tac1 Gene in Rat Hippocampal Primary Cells.. J Mol Neurosci..
Modulation of orbitofrontal response to amphetamine by a functional variant of DAT1 and in vitro confirmation.
Brotons, O., O'Daly, O. G., Guindalini, C., Howard, M., Bubb, J., Barker, G., . . . Shergill, S. S. (2010). Modulation of orbitofrontal response to amphetamine by a functional variant of DAT1 and in vitro confirmation.. Mol Psychiatry..
2009
A regulatory domain spanning the repeat sequence RE1 from herpes simplex virus type 1 has cell specific differential functions in trigeminal neurons and fibroblasts
Stevens, H. C., Fiskerstrand, C., Bubb, V. J., Dalziel, R., & Quinn, J. P. (2009). A regulatory domain spanning the repeat sequence RE1 from herpes simplex virus type 1 has cell specific differential functions in trigeminal neurons and fibroblasts. FEBS LETTERS, 583(20), 3335-3338. doi:10.1016/j.febslet.2009.09.037
The human neurokinin B gene, TAC3, and its promoter are regulated by Neuron Restrictive Silencing Factor (NRSF) transcription factor family
Gillies, S., Haddley, K., Vasiliou, S., Bubb, V. J., & Quinn, J. P. (2009). The human neurokinin B gene, TAC3, and its promoter are regulated by Neuron Restrictive Silencing Factor (NRSF) transcription factor family. NEUROPEPTIDES, 43(4), 333-340. doi:10.1016/j.npep.2009.05.004
'A regulatory domain spanning the repeat sequence RE1 from herpes simplex virus type 1 has cell specific differential functions in trigeminal neurons and fibroblasts.'
Stevens, H. C., Fiskerstrand, C., Bubb, V. J., Dalziel, R., & Quinn, J. P. (2009). 'A regulatory domain spanning the repeat sequence RE1 from herpes simplex virus type 1 has cell specific differential functions in trigeminal neurons and fibroblasts.'. FEBS Letters, 583(20), 3335-3338.
2008
Regulation of activity-dependent neuroprotective, protein (ADNP) by the NO-cGMP pathway in the hippocampus during kainic acid-induced
Cosgrave, A. S., Mckay, J. S., Bubb, V., Morris, R., Quinn, J. P., & Thippeswamy, T. (2008). Regulation of activity-dependent neuroprotective, protein (ADNP) by the NO-cGMP pathway in the hippocampus during kainic acid-induced. NEUROBIOLOGY OF DISEASE, 30(3), 281-292. doi:10.1016/j.nbd.2008.02.005
Molecular genetics of monoamine transporters: Relevance to brain disorders
Haddley, K., Vasiliou, A. S., Ali, F. R., Paredes, U. M., Bubb, V. J., & Quinn, J. P. (2008). Molecular genetics of monoamine transporters: Relevance to brain disorders. NEUROCHEMICAL RESEARCH, 33(4), 652-667. doi:10.1007/s11064-007-9521-8
Expression of activity-dependent neuroprotective protein in the brain of adult rats
Gennet, N., Herden, C., Bubb, V. J., Quinn, J. P., & Kipar, A. (2008). Expression of activity-dependent neuroprotective protein in the brain of adult rats. HISTOLOGY AND HISTOPATHOLOGY, 23(3), 309-317. Retrieved from https://www.webofscience.com/
Expression of ADNP in the brain of adult rats.
Gennet, N., Herden, C., Bubb, V. J., Quinn, J. P., & Kipar, A. (2008). Expression of ADNP in the brain of adult rats.. Histology and Histopathology, 23(3), 209-217.
2007
Generation of a transgenic model to address regulation and function of the human neurokinin 1 receptor (NK1R)
Vasiliou, A. S., MacKenzie, A., Morris, R., McLaughlin, L., Bubb, V. J., Haddley, K., & Quinn, J. P. (2007). Generation of a transgenic model to address regulation and function of the human neurokinin 1 receptor (NK1R). Neuropeptides, 41(4), 195-205. doi:10.1016/j.npep.2007.04.005
Generation of a transgenic model to address regulation and function of the human neurokinin 1 receptor (NK1R)
Vasiliou, A. S., MacKenzie, A., Morris, R., McLaughlin, L., Bubb, V. J., Haddley, K., & Quinn, J. P. (2007). Generation of a transgenic model to address regulation and function of the human neurokinin 1 receptor (NK1R). NEUROPEPTIDES, 41(4), 195-205. doi:10.1016/j.npep.2007.04.005
Evidence of postnatal neurogenesis in dorsal root ganglion: Role of nitric oxide and neuronal restrictive silencer transcription factor
Arora, D. K., Cosgrave, A. S., Howard, M. R., Bubb, V., Quinn, J. P., & Thippeswamy, T. (2007). Evidence of postnatal neurogenesis in dorsal root ganglion: Role of nitric oxide and neuronal restrictive silencer transcription factor. JOURNAL OF MOLECULAR NEUROSCIENCE, 32(2), 97-107. doi:10.1007/s12031-007-0014-7
Differential regulation of the serotonin transporter gene by lithium is mediated by transcription factors, CCCTC binding protein and Y-box binding protein 1, through the polymorphic intron 2 variable number tandem repeat
Roberts, J., Scott, A. C., Howard, M. R., Breen, G., Bubb, V. J., Klenova, E., & Quinn, J. P. (2007). Differential regulation of the serotonin transporter gene by lithium is mediated by transcription factors, CCCTC binding protein and Y-box binding protein 1, through the polymorphic intron 2 variable number tandem repeat. JOURNAL OF NEUROSCIENCE, 27(11), 2793-2801. doi:10.1523/JNEUROSCI.0892-06.2007
2006
A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample
Guindalini, C., Howard, M., Haddley, K., Laranjeira, R., Collier, D., Ammar, N., . . . Breen, G. (2006). A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(12), 4552-4557. doi:10.1073/pnas.0504789103
2004
YB-1 and CTCF differentially regulate the 5-HTT polymorphic intron 2 enhancer which predisposes to a variety of neurological disorders
Klenova, E., Scott, A. C., Roberts, J., Shamsuddin, S., Lovejoy, E. A., Bergmann, S., . . . Quinn, J. P. (2004). YB-1 and CTCF differentially regulate the 5-HTT polymorphic intron 2 enhancer which predisposes to a variety of neurological disorders. JOURNAL OF NEUROSCIENCE, 24(26), 5966-5973. doi:10.1523/JNEUROSCI.1150-04.2004
2003
The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit
Lovejoy, E. A., Scott, A. C., Fiskerstrand, C. E., Bubb, V. J., & Quinn, J. P. (2003). The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit. EUROPEAN JOURNAL OF NEUROSCIENCE, 17(2), 417-420. doi:10.1046/j.1460-9568.2003.02446.x
2002
Neuron restrictive silencer factor as a modulator of neuropeptide gene expression
Quinn, J. P., Bubb, V. J., Marshall-Jones, Z. V., & Coulson, J. M. (2002). Neuron restrictive silencer factor as a modulator of neuropeptide gene expression. REGULATORY PEPTIDES, 108(2-3), 135-141. doi:10.1016/S0167-0115(02)00103-9
Evidence for an age-related influence of microsatellite instability on colorectal cancer survival.
Farrington, S. M., McKinley, A. J., Carothers, A. D., Cunningham, C., Bubb, V. J., Sharp, L., . . . Dunlop, M. G. (2002). Evidence for an age-related influence of microsatellite instability on colorectal cancer survival.. International journal of cancer, 98(6), 844-850. doi:10.1002/ijc.10264
Neuron restrictive silencer factor as a modulator of neuropeptide gene expression.
Quinn, J. P., Bubb, V. J., Marshall-Jones, Z. V., & Coulson, J. M. (2002). Neuron restrictive silencer factor as a modulator of neuropeptide gene expression.. Regulatory Peptides, 108(2-3), 1-9.
2001
Adenomatous polyposis coli (APC), beta-catenin, and cadherin are expressed in human bone and cartilage.
Monaghan, H., Bubb, V. J., Sirimujalin, R., Millward-Sadler, S. J., & Salter, D. M. (2001). Adenomatous polyposis coli (APC), beta-catenin, and cadherin are expressed in human bone and cartilage.. Histopathology, 39(6), 611-619. doi:10.1046/j.1365-2559.2001.01287.x
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study.
Andreyev, H. J., Norman, A. R., Cunningham, D., Oates, J., Dix, B. R., Iacopetta, B. J., . . . Urosevic, N. (2001). Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study.. British journal of cancer, 85(5), 692-696. doi:10.1054/bjoc.2001.1964
2000
Familial adenomatous polyposis coli in South Africa--molecular basis and diagnosis.
Grobbelaar, J. J., Fortuin, R., Scholtz, C. L., Zikind, A., Langenhoven, E., Wyllie, A. H., . . . Kotze, M. J. (2000). Familial adenomatous polyposis coli in South Africa--molecular basis and diagnosis.. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 90(7), 715-719.
1999
Dysregulated expression of beta-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.
Kongkanuntn, R., Bubb, V. J., Sansom, O. J., Wyllie, A. H., Harrison, D. J., & Clarke, A. R. (1999). Dysregulated expression of beta-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.. Oncogene, 18(51), 7219-7225. doi:10.1038/sj.onc.1203181
Apoptosis and carcinogenesis.
Wyllie, A. H., Bellamy, C. O., Bubb, V. J., Clarke, A. R., Corbet, S., Curtis, L., . . . Bird, C. C. (1999). Apoptosis and carcinogenesis.. In British journal of cancer Vol. 80 Suppl 1 (pp. 34-37).
Caspase-mediated cleavage of APC results in an amino-terminal fragment with an intact armadillo repeat domain.
Webb, S. J., Nicholson, D., Bubb, V. J., & Wyllie, A. H. (1999). Caspase-mediated cleavage of APC results in an amino-terminal fragment with an intact armadillo repeat domain.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 13(2), 339-346. doi:10.1096/fasebj.13.2.339
1997
APC expression in normal human tissues.
Midgley, C. A., White, S., Howitt, R., Save, V., Dunlop, M. G., Hall, P. A., . . . Bubb, V. J. (1997). APC expression in normal human tissues.. The Journal of pathology, 181(4), 426-433. doi:3.0.co;2-t">10.1002/(sici)1096-9896(199704)181:4<426::aid-path768>3.0.co;2-t
The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung.
Cooper, C. A., Carby, F. A., Bubb, V. J., Lamb, D., Kerr, K. M., & Wyllie, A. H. (1997). The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung.. The Journal of pathology, 181(4), 401-404. doi:3.0.co;2-y">10.1002/(sici)1096-9896(199704)181:4<401::aid-path799>3.0.co;2-y
1996
Loss of heterozygosity at 5q21 in non-small cell lung cancer: a frequent event but without evidence of apc mutation.
Cooper, C. A., Bubb, V. J., Smithson, N., Carter, R. L., Gledhill, S., Lamb, D., . . . Carey, F. A. (1996). Loss of heterozygosity at 5q21 in non-small cell lung cancer: a frequent event but without evidence of apc mutation.. The Journal of pathology, 180(1), 33-37. doi:3.0.co;2-y">10.1002/(sici)1096-9896(199609)180:1<33::aid-path642>3.0.co;2-y
Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer.
Bubb, V. J., Curtis, L. J., Cunningham, C., Dunlop, M. G., Carothers, A. D., Morris, R. G., . . . Wyllie, A. H. (1996). Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer.. Oncogene, 12(12), 2641-2649.
Polymorphism in serotonin transporter gene associated with susceptibility to major depression.
Ogilvie, A. D., Battersby, S., Bubb, V. J., Fink, G., Harmar, A. J., Goodwim, G. M., & Smith, C. A. (1996). Polymorphism in serotonin transporter gene associated with susceptibility to major depression.. Lancet (London, England), 347(9003), 731-733. doi:10.1016/s0140-6736(96)90079-3
Extracolonic features of familial adenomatous polyposis in patients with sporadic colorectal cancer.
Dunlop, M. G., Farrington, S. M., Bubb, V. J., Cunningham, C., Wright, M., Curtis, L. J., . . . Wyllie, A. H. (1996). Extracolonic features of familial adenomatous polyposis in patients with sporadic colorectal cancer.. British journal of cancer, 74(11), 1789-1795. doi:10.1038/bjc.1996.631
Germline APC mutation (Gln1317) in a cancer-prone family that does not result in familial adenomatous polyposis.
White, S., Bubb, V. J., & Wyllie, A. H. (1996). Germline APC mutation (Gln1317) in a cancer-prone family that does not result in familial adenomatous polyposis.. Genes, chromosomes & cancer, 15(2), 122-128. doi:3.0.co;2-5">10.1002/(sici)1098-2264(199602)15:2<122::aid-gcc7>3.0.co;2-5
1994
Loss of heterozygosity of MCC is not associated with mutation of the retained allele in sporadic colorectal cancer.
Curtis, L. J., Bubb, V. J., Gledhill, S., Morris, R. G., Bird, C. C., & Wyllie, A. H. (1994). Loss of heterozygosity of MCC is not associated with mutation of the retained allele in sporadic colorectal cancer.. Human molecular genetics, 3(3), 443-446. doi:10.1093/hmg/3.3.443
Erratum: Loss of heterozygosity of MCC is not associated with mutation at the retained allele in sporadic colorectal cancer (Human Molecular Genetics (1994) 3 (443-446))
Curtis, L. J., Bubb, V. J., Gledhill, S., Morris, R. G., Bird, C. C., & Wyllie, A. H. (1994). Erratum: Loss of heterozygosity of MCC is not associated with mutation at the retained allele in sporadic colorectal cancer (Human Molecular Genetics (1994) 3 (443-446)). Human Molecular Genetics, 3(4), 684.
1993
The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein.
Conrad, M., Bubb, V. J., & Schlegel, R. (1993). The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein.. Journal of virology, 67(10), 6170-6178. doi:10.1128/jvi.67.10.6170-6178.1993
1991
Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPases.
Goldstein, D. J., Finbow, M. E., Andresson, T., McLean, P., Smith, K., Bubb, V., & Schlegel, R. (1991). Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPases.. Nature, 352(6333), 347-349. doi:10.1038/352347a0
1989
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.
Münger, K., Phelps, W. C., Bubb, V., Howley, P. M., & Schlegel, R. (1989). The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.. Journal of virology, 63(10), 4417-4421. doi:10.1128/jvi.63.10.4417-4421.1989
1988
DNA sequence of the HPV-16 E5 ORF and the structural conservation of its encoded protein.
Bubb, V., McCance, D. J., & Schlegel, R. (1988). DNA sequence of the HPV-16 E5 ORF and the structural conservation of its encoded protein.. Virology, 163(1), 243-246. doi:10.1016/0042-6822(88)90259-0