Publications
2024
P035 Good quality sleep is associated with initial encoding and long-term consolidation of memory in older adults
Akhtar, N., Garfield, V., Singh, A., Soni, R., Chakrawarty, A., Tripathi, M., & Shankar Kaloiya, G. (2024). P035 Good quality sleep is associated with initial encoding and long-term consolidation of memory in older adults. Sleep Advances, 5(Supplement_1), A41. doi:10.1093/sleepadvances/zpae070.117
Unpicking Causal Relationships Between Grip Strength and Cardiorespiratory Fitness: A Bidirectional Mendelian Randomization Study.
Norris, T., Cooper, R., Garfield, V., Hamer, M., & Pinto Pereira, S. M. (2024). Unpicking Causal Relationships Between Grip Strength and Cardiorespiratory Fitness: A Bidirectional Mendelian Randomization Study.. Scandinavian journal of medicine & science in sports, 34(12), e14775. doi:10.1111/sms.14775
Genetic and lifestyle risks for coronary artery disease and risk of incident dementia
Sittichokkananon, A., Garfield, V., & Chiesa, S. T. (2024). Genetic and lifestyle risks for coronary artery disease and risk of incident dementia. European Heart Journal, 45(Supplement_1). doi:10.1093/eurheartj/ehae666.2715
Corrigendum to <'Associations between residential daytime indoor temperature and self-reported sleep disturbances in UK adults: A cross-sectional study'> [Environ. Res. 257 (2024) 119281].
Deng, R., Garfield, V., & Ucci, M. (2024). Corrigendum to <'Associations between residential daytime indoor temperature and self-reported sleep disturbances in UK adults: A cross-sectional study'> [Environ. Res. 257 (2024) 119281].. Environmental research, 257, 119387. doi:10.1016/j.envres.2024.119387
Genetic and Lifestyle Risks for Coronary Artery Disease and Long-Term Risk of Incident Dementia Subtypes
Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity.
Chiesa, S. T., Rader, L., Garfield, V., Foote, I., Suri, S., Davey Smith, G., . . . Richardson, T. G. (2024). Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity.. Brain : a journal of neurology, awae198. doi:10.1093/brain/awae198
Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations.
Topriceanu, C. -C., Chaturvedi, N., Mathur, R., & Garfield, V. (2024). Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations.. European journal of human genetics : EJHG, 32(6), 697-707. doi:10.1038/s41431-023-01517-3
Early-life cumulative exposure to excess bodyweight and midlife cognitive function: longitudinal analysis in three British birth cohorts.
Chiesa, S. T., Norris, T., Garfield, V., Richards, M., & Hughes, A. D. (2024). Early-life cumulative exposure to excess bodyweight and midlife cognitive function: longitudinal analysis in three British birth cohorts.. The lancet. Healthy longevity, 5(3), e204-e213. doi:10.1016/s2666-7568(24)00005-9
Associations of a multidimensional polygenic sleep health score and a sleep lifestyle index on health outcomes and their interaction in a clinical biobank.
Right hippocampus volume correlates with sleep spindle generation probability in good sleepers: a neuroloop gain analysis study in older adults
Soni, R., Akhtar, N., Garfield, V., Kumaran, S. S., Devarajan S, L. J., Chakrawarty, A., & Kaloiya, G. (2024). Right hippocampus volume correlates with sleep spindle generation probability in good sleepers: a neuroloop gain analysis study in older adults. Sleep Medicine, 115, S7-S8. doi:10.1016/j.sleep.2023.11.059
A brief comparison of polygenic risk scores and Mendelian randomisation.
Garfield, V., & Anderson, E. L. (2024). A brief comparison of polygenic risk scores and Mendelian randomisation.. BMC medical genomics, 17(1), 10. doi:10.1186/s12920-023-01769-4
The Role of Circadian Rhythms and Sleep in Anorexia Nervosa.
Wilcox, H., Paz, V., Saxena, R., Winkelman, J. W., Garfield, V., & Dashti, H. S. (2024). The Role of Circadian Rhythms and Sleep in Anorexia Nervosa.. JAMA network open, 7(1), e2350358. doi:10.1001/jamanetworkopen.2023.50358
A cross-sectional observational study for ethno-geographical disparities in sleep quality, brain morphometry and cognition (a SOLACE study) in Indians residing in India, and South Asians and Europeans residing in the UK - a study protocol.
Soni, R., Dale, C., Garfield, V., & Akhtar, N. (2024). A cross-sectional observational study for ethno-geographical disparities in sleep quality, brain morphometry and cognition (a SOLACE study) in Indians residing in India, and South Asians and Europeans residing in the UK - a study protocol.. Frontiers in aging neuroscience, 16, 1294681. doi:10.3389/fnagi.2024.1294681
2023
Artificial intelligence for dementia genetics and omics.
Bettencourt, C., Skene, N., Bandres-Ciga, S., Anderson, E., Winchester, L. M., Foote, I. F., . . . Llewellyn, D. J. (2023). Artificial intelligence for dementia genetics and omics.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 19(12), 5905-5921. doi:10.1002/alz.13427
Selection of genetic instruments in Mendelian randomisation studies of sleep traits.
Paz, V., Dashti, H. S., Burgess, S., & Garfield, V. (2023). Selection of genetic instruments in Mendelian randomisation studies of sleep traits.. Sleep medicine, 112, 342-351. doi:10.1016/j.sleep.2023.10.036
Abstract 14266: Is the Association Between Coronary Artery Disease and Adverse Brain Health Causal? A Combined Observational and Mendelian Randomisation Study
Topriceanu, C. -C., Hussain, R., Dale, C., Park, C. M., Chaturvedi, N., FATEMIFAR, G., & Garfield, V. (2023). Abstract 14266: Is the Association Between Coronary Artery Disease and Adverse Brain Health Causal? A Combined Observational and Mendelian Randomisation Study. Circulation, 148(Suppl_1). doi:10.1161/circ.148.suppl_1.14266
Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study.
Norris, T., Sanderson, E., Cooper, R., Garfield, V., & Pereira, S. M. P. (2023). Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study.. Scientific reports, 13(1), 16886. doi:10.1038/s41598-023-43908-y
Is there an association between daytime napping, cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank.
Paz, V., Dashti, H. S., & Garfield, V. (2023). Is there an association between daytime napping, cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank.. Sleep health, 9(5), 786-793. doi:10.1016/j.sleh.2023.05.002
Sex-specific risks for cardiovascular disease across the glycaemic spectrum: a population-based cohort study using the UK Biobank.
Rentsch, C. T., Garfield, V., Mathur, R., Eastwood, S. V., Smeeth, L., Chaturvedi, N., & Bhaskaran, K. (2023). Sex-specific risks for cardiovascular disease across the glycaemic spectrum: a population-based cohort study using the UK Biobank.. The Lancet regional health. Europe, 32, 100693. doi:10.1016/j.lanepe.2023.100693
Linear and Nonlinear Associations Between Vitamin D and Grip Strength: A Mendelian Randomization Study in UK Biobank.
Pinto Pereira, S. M., Garfield, V., Norris, T., Burgess, S., Williams, D. M., Dodds, R., . . . Cooper, R. (2023). Linear and Nonlinear Associations Between Vitamin D and Grip Strength: A Mendelian Randomization Study in UK Biobank.. The journals of gerontology. Series A, Biological sciences and medical sciences, 78(8), 1483-1488. doi:10.1093/gerona/glac255
The relationship between adiposity and cognitive function: a bidirectional Mendelian randomization study in UK Biobank.
Norris, T., Salzmann, A., Henry, A., Garfield, V., & Pinto Pereira, S. M. (2023). The relationship between adiposity and cognitive function: a bidirectional Mendelian randomization study in UK Biobank.. International journal of epidemiology, 52(4), 1074-1085. doi:10.1093/ije/dyad043
Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian Randomization study
190 Validity of cardiovascular polygenic risk scores mostly derived from europeans in multi-ethnic populations
Topriceanu, C., Garfield, V., Mathur, R., & Chaturvedi, N. (2023). 190 Validity of cardiovascular polygenic risk scores mostly derived from europeans in multi-ethnic populations. In Stable IHD/Prevention/Hypertension/Lipids (pp. A219.2-A221). BMJ Publishing Group Ltd and British Cardiovascular Society. doi:10.1136/heartjnl-2023-bcs.190
0086 Good quality sleep facilitates psychomotor learning via fast spindles among older adults
Akhtar, N., Soni, R., Chakrawarty, A., Kaloiya, G. S., & Garfield, V. (2023). 0086 Good quality sleep facilitates psychomotor learning via fast spindles among older adults. SLEEP, 46(Supplement_1), A39. doi:10.1093/sleep/zsad077.0086
Validity of European-centric derived cardiometabolic polygenic risk scores in multi-ancestry populations
Sex-specific risks for cardiovascular disease across the glycaemic spectrum: a population-based cohort study using the UK Biobank
A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach.
Garfield, V., Salzmann, A., Burgess, S., & Chaturvedi, N. (2023). A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach.. Diabetes, 72(2), 175-183. doi:10.2337/db22-0110
Testing for association between exonic glucagon-like peptide 1 receptor mutation with physical and brain health traits in UK Biobank.
Ward, J., Lyall, L. M., Strawbridge, R. J., Stanciu, I., Veldsman, M., Garfield, V., . . . Lyall, D. M. (2023). Testing for association between exonic glucagon-like peptide 1 receptor mutation with physical and brain health traits in UK Biobank.. Diabetes, obesity & metabolism, 25(2), 623-627. doi:10.1111/dom.14879
2022
Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records.
Muzambi, R., Bhaskaran, K., Rentsch, C. T., Smeeth, L., Brayne, C., Garfield, V., . . . Warren-Gash, C. (2022). Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records.. Translational psychiatry, 12(1), 385. doi:10.1038/s41398-022-02145-z
Adiposity and grip strength: a Mendelian randomisation study in UK Biobank.
Pinto Pereira, S. M., Garfield, V., Farmaki, A. -E., Tomlinson, D. J., Norris, T., Fatemifar, G., . . . Cooper, R. (2022). Adiposity and grip strength: a Mendelian randomisation study in UK Biobank.. BMC medicine, 20(1), 201. doi:10.1186/s12916-022-02393-2
Understanding the inter-relationships of type 2 diabetes and hypertension with brain and cognitive health: A UK Biobank study.
Newby, D., & Garfield, V. (2022). Understanding the inter-relationships of type 2 diabetes and hypertension with brain and cognitive health: A UK Biobank study.. Diabetes, obesity & metabolism, 24(5), 938-947. doi:10.1111/dom.14658
Type 2 diabetes risks and determinants in second-generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK.
Farmaki, A. -E., Garfield, V., Eastwood, S. V., Farmer, R. E., Mathur, R., Giannakopoulou, O., . . . Chaturvedi, N. (2022). Type 2 diabetes risks and determinants in second-generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK.. Diabetologia, 65(1), 113-127. doi:10.1007/s00125-021-05580-7
2021
Understanding the interrelationships of type-2 diabetes and hypertension with brain and cognitive health: a UK Biobank study
Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank.
Garfield, V., Farmaki, A. -E., Fatemifar, G., Eastwood, S. V., Mathur, R., Rentsch, C. T., . . . Chaturvedi, N. (2021). Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank.. Diabetes, 70(10), 2313-2321. doi:10.2337/db20-0895
Is there an association between daytime napping, cognitive function and brain volume? A Mendelian randomisation study in the UK Biobank
The association between plasma metabolites and sleep quality in the Southall and Brent Revisited (SABRE) Study: A cross-sectional analysis.
Topriceanu, C. -C., Tillin, T., Chaturvedi, N., Joshi, R., & Garfield, V. (2021). The association between plasma metabolites and sleep quality in the Southall and Brent Revisited (SABRE) Study: A cross-sectional analysis.. Journal of sleep research, 30(4), e13245. doi:10.1111/jsr.13245
Shared genetic architecture underlying sleep and weight in children.
Garfield, V., Llewellyn, C. H., Wichstrøm, L., & Steinsbekk, S. (2021). Shared genetic architecture underlying sleep and weight in children.. Sleep medicine, 83, 40-44. doi:10.1016/j.sleep.2021.04.021
Association between sleep quality and type 2 diabetes at 20-year follow-up in the Southall and Brent REvisited (SABRE) cohort: a triethnic analysis.
Ong, Z. L., Chaturvedi, N., Tillin, T., Dale, C., & Garfield, V. (2021). Association between sleep quality and type 2 diabetes at 20-year follow-up in the Southall and Brent REvisited (SABRE) cohort: a triethnic analysis.. Journal of epidemiology and community health, 75(11), 1117-1122. doi:10.1136/jech-2020-215796
Investigating the Relationship Between IGF-I, IGF-II, and IGFBP-3 Concentrations and Later-Life Cognition and Brain Volume.
Salzmann, A., James, S. -N., Williams, D. M., Richards, M., Cadar, D., Schott, J. M., . . . Garfield, V. (2021). Investigating the Relationship Between IGF-I, IGF-II, and IGFBP-3 Concentrations and Later-Life Cognition and Brain Volume.. The Journal of clinical endocrinology and metabolism, 106(6), 1617-1629. doi:10.1210/clinem/dgab121
HbA1c and brain health across the entire glycaemic spectrum.
Garfield, V., Farmaki, A. -E., Eastwood, S. V., Mathur, R., Rentsch, C. T., Bhaskaran, K., . . . Chaturvedi, N. (2021). HbA1c and brain health across the entire glycaemic spectrum.. Diabetes, obesity & metabolism, 23(5), 1140-1149. doi:10.1111/dom.14321
Sleep duration: A review of genome-wide association studies (GWAS) in adults from 2007 to 2020.
Garfield, V. (2021). Sleep duration: A review of genome-wide association studies (GWAS) in adults from 2007 to 2020.. Sleep medicine reviews, 56, 101413. doi:10.1016/j.smrv.2020.101413
2020
Investigating the relationship between IGF-I, -II and IGFBP-3 concentrations and later-life cognition and brain volume
The relationship between cognitive function and sleep duration: a Mendelian randomisation study
Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank.
Rentsch, C. T., Farmer, R. E., Eastwood, S. V., Mathur, R., Garfield, V., Farmaki, A. -E., . . . Smeeth, L. (2020). Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank.. BMJ open diabetes research & care, 8(1), e001600. doi:10.1136/bmjdrc-2020-001600
The Association between Sleep Quality and Type Two Diabetes at 20 Year Follow-up in the Southall And Brent REvisited (SABRE) Cohort: a Tri-ethnic Analysis
The association between plasma metabolites and sleep quality in the Southall and Brent Revisited Study (SABRE): A cross-sectional analysis
The relationship between glycaemia, cognitive function, structural brain outcomes and dementia: A Mendelian randomization study in the UK Biobank
Is glycaemia associated with poorer brain health and risk of dementia? Cross sectional and follow-up analysis of the UK Biobank
2019
Type 2 diabetes risks and determinants in 2<sup>nd</sup> generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK
The Association Between Body Mass Index (BMI) and Sleep Duration: Where Are We after nearly Two Decades of Epidemiological Research?
Garfield, V. (2019). The Association Between Body Mass Index (BMI) and Sleep Duration: Where Are We after nearly Two Decades of Epidemiological Research?. International journal of environmental research and public health, 16(22), E4327. doi:10.3390/ijerph16224327
The relationship between sleep quality and all-cause, CVD and cancer mortality: the Southall and Brent REvisited study (SABRE).
Garfield, V., Joshi, R., Garcia-Hernandez, J., Tillin, T., & Chaturvedi, N. (2019). The relationship between sleep quality and all-cause, CVD and cancer mortality: the Southall and Brent REvisited study (SABRE).. Sleep medicine, 60, 230-235. doi:10.1016/j.sleep.2019.03.012
The relationship between sleep duration, cognition and dementia: a Mendelian randomization study.
Henry, A., Katsoulis, M., Masi, S., Fatemifar, G., Denaxas, S., Acosta, D., . . . Dale, C. E. (2019). The relationship between sleep duration, cognition and dementia: a Mendelian randomization study.. International journal of epidemiology, 48(3), 849-860. doi:10.1093/ije/dyz071
Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals.
Garfield, V., Fatemifar, G., Dale, C., Smart, M., Bao, Y., Llewellyn, C. H., . . . Kumari, M. (2019). Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals.. Genetic epidemiology, 43(2), 207-214. doi:10.1002/gepi.22174
2017
Investigating the Bidirectional Associations of Adiposity with Sleep Duration in Older Adults: The English Longitudinal Study of Ageing (ELSA).
Garfield, V., Llewellyn, C. H., Steptoe, A., & Kumari, M. (2017). Investigating the Bidirectional Associations of Adiposity with Sleep Duration in Older Adults: The English Longitudinal Study of Ageing (ELSA).. Scientific reports, 7, 40250. doi:10.1038/srep40250
2016
The relationship between physical activity, sleep duration and depressive symptoms in older adults: The English Longitudinal Study of Ageing (ELSA).
Garfield, V., Llewellyn, C. H., & Kumari, M. (2016). The relationship between physical activity, sleep duration and depressive symptoms in older adults: The English Longitudinal Study of Ageing (ELSA).. Preventive medicine reports, 4, 512-516. doi:10.1016/j.pmedr.2016.09.006
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay, A., Baselmans, B. M. L., De Neve, J. -E., Turley, P., Nivard, M. G., Fontana, M. A., . . . Cesarini, D. (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.. Nature genetics, 48(6), 624-633. doi:10.1038/ng.3552
Preschool Drawing and School Mathematics: The Nature of the Association.
Malanchini, M., Tosto, M. G., Garfield, V., Dirik, A., Czerwik, A., Arden, R., . . . Kovas, Y. (2016). Preschool Drawing and School Mathematics: The Nature of the Association.. Child development, 87(3), 929-943. doi:10.1111/cdev.12520
2015
Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism
2014
Genes influence young children's human figure drawings and their association with intelligence a decade later.
Arden, R., Trzaskowski, M., Garfield, V., & Plomin, R. (2014). Genes influence young children's human figure drawings and their association with intelligence a decade later.. Psychological science, 25(10), 1843-1850. doi:10.1177/0956797614540686