Publications
2024
The pharmacokinetic differences between 10- and 15-μg daily vitamin D doses.
You, T., Muhamad, N., Jenner, J., & Huang, Z. (2024). The pharmacokinetic differences between 10- and 15-μg daily vitamin D doses.. British journal of clinical pharmacology. doi:10.1111/bcp.16146
2023
The Pharmacokinetics Difference between 10µg and 15µg Daily Vitamin D Doses
2022
Comparative assessment of viral dynamic models for SARS-CoV-2 for pharmacodynamic assessment in early treatment trials.
Agyeman, A. A., You, T., Chan, P. L. S., Lonsdale, D. O., Hadjichrysanthou, C., Mahungu, T., . . . Standing, J. F. (2022). Comparative assessment of viral dynamic models for SARS-CoV-2 for pharmacodynamic assessment in early treatment trials.. British journal of clinical pharmacology, 88(12), 5428-5433. doi:10.1111/bcp.15518
UK CTAP Briefing on Ivermectin.
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Ivermectin. (DOI: 10.5281/zenodo.6011345.).
UK CTAP Briefing on Vitamin D. National Core Studies
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Vitamin D. National Core Studies (DOI: 10.5281/zenodo.6011333.).
Choosing drugs for UK COVID-19 treatment trials.
Chinnery, P. F., Bonnet, M., Cave, A., Hofer, M. P., Lamb, A., McConkey, G. A., . . . You, T. (2022). Choosing drugs for UK COVID-19 treatment trials.. Nature reviews. Drug discovery, 21(2), 81-82. doi:10.1038/d41573-021-00203-7
2021
Personalise vitamin D<sub>3</sub> using physiologically based pharmacokinetic modelling.
Huang, Z., & You, T. (2021). Personalise vitamin D<sub>3</sub> using physiologically based pharmacokinetic modelling.. CPT: pharmacometrics & systems pharmacology, 10(7), 723-734. doi:10.1002/psp4.12640
2018
A mathematical model of antibody-dependent cellular cytotoxicity (ADCC).
Hoffman, F., Gavaghan, D., Osborne, J., Barrett, I. P., You, T., Ghadially, H., . . . Byrne, H. M. (2018). A mathematical model of antibody-dependent cellular cytotoxicity (ADCC).. Journal of theoretical biology, 436, 39-50. doi:10.1016/j.jtbi.2017.09.031
2015
Investigating receptor enzyme activity using time-scale analysis.
You, T., & Yue, H. (2015). Investigating receptor enzyme activity using time-scale analysis.. IET systems biology, 9(6), 268-276. doi:10.1049/iet-syb.2015.0037
2014
Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence
You, T., & Yue, H. (2014). Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence. In 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (pp. 38-43). IEEE. doi:10.1109/bibm.2014.6999257
Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.
Kaloriti, D., Jacobsen, M., Yin, Z., Patterson, M., Tillmann, A., Smith, D. A., . . . Brown, A. J. P. (2014). Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.. mBio, 5(4), e01334-e01314. doi:10.1128/mbio.01334-14
2013
Eukaryotic translation initiation factor interactions
You, T., Coghill, G., & Brown, A. (2013). Eukaryotic translation initiation factor interactions. In Encyclopedia of Systems Biology. Springer.
Translational control of GCN4
You, T., Coghill, G., & Brown, A. (2013). Translational control of GCN4. In Encyclopedia of Systems Biology. Springer.
2012
Combinatorial stresses kill pathogenic Candida species.
Kaloriti, D., Tillmann, A., Cook, E., Jacobsen, M., You, T., Lenardon, M., . . . Brown, A. J. P. (2012). Combinatorial stresses kill pathogenic Candida species.. Medical mycology, 50(7), 699-709. doi:10.3109/13693786.2012.672770
A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi.
You, T., Ingram, P., Jacobsen, M. D., Cook, E., McDonagh, A., Thorne, T., . . . Brown, A. J. P. (2012). A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi.. BMC research notes, 5, 258. doi:10.1186/1756-0500-5-258
2011
Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation.
You, T., Stansfield, I., Romano, M. C., Brown, A. J. P., & Coghill, G. M. (2011). Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation.. BMC systems biology, 5, 131. doi:10.1186/1752-0509-5-131
2010
A quantitative model for mRNA translation in Saccharomyces cerevisiae.
You, T., Coghill, G. M., & Brown, A. J. P. (2010). A quantitative model for mRNA translation in Saccharomyces cerevisiae.. Yeast (Chichester, England), 27(10), 785-800. doi:10.1002/yea.1770
2009
Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae
You, T. (2009, May 23). Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae.
2006
Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis.
Bi, X., Lin, Q., Foo, T. W., Joshi, S., You, T., Shen, H. -M., . . . Hew, C. -L. (2006). Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis.. Molecular & cellular proteomics : MCP, 5(6), 1119-1130. doi:10.1074/mcp.m500432-mcp200
SPLASH: systematic proteomics laboratory analysis and storage hub.
Lo, S. L., You, T., Lin, Q., Joshi, S. B., Chung, M. C. M., & Hew, C. L. (2006). SPLASH: systematic proteomics laboratory analysis and storage hub.. Proteomics, 6(6), 1758-1769. doi:10.1002/pmic.200500378