Research
Research grants
Development of non-covalent binders to SOD1 with scope for developing as PROTAC degraders of SOD1 for the treatment of MND
MOTOR NEURONE DISEASE ASSOCIATION (UK)
October 2023 - January 2027
Towards a paradigm shift in understanding of membrane-bound Nitric Oxide reductase and its complexes with the electron donor and NO-producing enzyme
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
November 2023 - November 2026
Characterisation of novel cardiac troponin I mutants associated with human hypertrophic cardiomyopathy
BRITISH HEART FOUNDATION (UK)
December 2021 - January 2025
A new generation of Crystallographic detector for Multi-user Barkla X-ray laboratory
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
July 2017 - July 2018
Damage Free structures of quinol dependent nitric oxide reductase (qNOR) in complex with nitrite reductase (NiR) from A. xylosoxidans
SCIENCE AND TECHNOLOGY FACILITIES COUNCIL
September 2015 - September 2019
Why does Nature use modular enzyme architectures for biological catalysis
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
January 2017 - July 2020
Structure-function studies of faulty proteins and their complexes involved in motor neuron disease
MOTOR NEURONE DISEASE ASSOCIATION
October 2015 - September 2018
2014 allocation - Wellcome ISSF non clinical fellowships
WELLCOME TRUST (UK)
May 2015 - October 2018
The cause and effect of SOD1 destabilization on motor neuron disease
MEDICAL RESEARCH FOUNDATION (UK)
October 2015 - April 2019
Proteins involved in Neurodegeneration
SOCIETE CIVILE SYNCHROTRON SOLEIL (FRANCE)
October 2014 - September 2017
TDP-43 and the molecular causes of its pathogenicity in neurodegenerative disease
MOTOR NEURONE DISEASE ASSOCIATION
October 2011 - February 2015
Transient and Stable Macromolecular complexes formed by Denitrifying Enzymes
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
June 2014 - June 2019
New challenges of Structural biology arising from the emergence of brilliant X-ray beams from X-ray Lasers
SCIENCE AND TECHNOLOGY FACILITIES COUNCIL
July 2014 - June 2018
YEAR 1 Wellcome Trust ISSF Non-Clinical Fellowships
WELLCOME TRUST (UK)
October 2011 - May 2018
Structural studies of proteins related to liver disease
CIC BIOGUNE (SPAIN)
September 2011 - August 2015
Research collaborations
John Collinge
MRC Centre for Neurodegeneration Research
Structural studies of human prion protein.