Publications
Selected publications
- Long-term cisplatin nephrotoxicity after childhood cancer: a systematic review and meta-analysis (Journal article - 2024)
- 5-ASA induced interstitial nephritis in patients with inflammatory bowel disease: a systematic review (Journal article - 2022)
- Vancomycin-associated acute kidney injury epidemiology in children: a systematic review (Journal article - 2022)
- Assessment of creatinine concentration in whole blood spheroids using paper spray ionization–tandem mass spectrometry (Journal article - 2022)
- Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy (Journal article - 2020)
- A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis. (Journal article - 2020)
- Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin (Journal article - 2018)
- Aminoglycoside-induced nephrotoxicity in children (Journal article - 2017)
- Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children (Journal article - 2014)
- Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study (Journal article - 2012)
2024
Long-term cisplatin nephrotoxicity after childhood cancer: a systematic review and meta-analysis
Schofield, J., Harcus, M., Pizer, B., Jorgensen, A., & McWilliam, S. (n.d.). Long-term cisplatin nephrotoxicity after childhood cancer: a systematic review and meta-analysis. Pediatric Nephrology. doi:10.1007/s00467-023-06149-9
2022
Prescribing in paediatric kidney impairment
Dowsett, T., Awan, S., & McWilliam, S. (2022). Prescribing in paediatric kidney impairment. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 107(6), 460-464. doi:10.1136/archdischild-2021-322781
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review
Shamsaee, E., Huws, A., Gill, A., McWilliam, S. J., & Hawcutt, D. B. (n.d.). Ibuprofen efficacy, tolerability and safety in obese children: a systematic review. Archives of Disease in Childhood. doi:10.1136/archdischild-2022-324652
Vancomycin-associated acute kidney injury epidemiology in children: a systematic review
Williams, C., Hankinson, C., McWilliam, S. J., & Oni, L. (2022). Vancomycin-associated acute kidney injury epidemiology in children: a systematic review. ARCHIVES OF DISEASE IN CHILDHOOD, 107(10), 947-954. doi:10.1136/archdischild-2021-323429
Assessment of creatinine concentration in whole blood spheroids using paper spray ionization–tandem mass spectrometry
Sham, T. -T., Badu-Tawiah, A. K., McWilliam, S. J., & Maher, S. (n.d.). Assessment of creatinine concentration in whole blood spheroids using paper spray ionization–tandem mass spectrometry. Scientific Reports, 12(1). doi:10.1038/s41598-022-18365-8
459 Nephrotoxin-associated AKI in non-critically ill children: A single centre prospective audit
Hankinson, C., Oni, L., Jorgensen, A., & McWilliam, S. (2022). 459 Nephrotoxin-associated AKI in non-critically ill children: A single centre prospective audit. In British Association for Community Child Health (pp. A92.3-A93). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.150
Nephrotoxic drugs and renal function in preterm infants: are urinary biomarkers the answer?
McWilliam, S. J., Turner, M. A., & Davis, J. M. (2022). Nephrotoxic drugs and renal function in preterm infants: are urinary biomarkers the answer?. PEDIATRIC RESEARCH, 92(1), 22-24. doi:10.1038/s41390-022-02049-0
5-ASA induced interstitial nephritis in patients with inflammatory bowel disease: a systematic review
Moss, J. G., Parry, C. M., Holt, R. C. L., & McWilliam, S. J. (2022). 5-ASA induced interstitial nephritis in patients with inflammatory bowel disease: a systematic review. EUROPEAN JOURNAL OF MEDICAL RESEARCH, 27(1). doi:10.1186/s40001-022-00687-y
Ambient ion focusing for paper spray ionisation
Smith, B. L., Boisdon, C., Romero-Perez, D., Sham, T. -T., Bastani, B., Zhou, Y., . . . Maher, S. (2022). Ambient ion focusing for paper spray ionisation. International Journal of Mass Spectrometry, 116737. doi:10.1016/j.ijms.2021.116737
Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital
Hawcutt, D. B., Warner, N., Kenyon, E., Murray, C., Taylor, J., Moss, J., . . . Murdock, N. (2022). Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(1), 206-213. doi:10.1111/bcp.14944
Information for children and young people about reporting suspected adverse drug reactions
Hawcutt, D. B., Jadeja, M., Bhoombla, N., Smith, S., & McWilliam, S. J. (2022). Information for children and young people about reporting suspected adverse drug reactions. ARCHIVES OF DISEASE IN CHILDHOOD, 107(7), 681-685. doi:10.1136/archdischild-2021-323400
2021
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial.
Arabi, Y. M., Gordon, A. C., Derde, L. P. G., Nichol, A. D., Murthy, S., Al Beidh, F., . . . Webb, S. A. (2021). Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. INTENSIVE CARE MEDICINE, 47(8), 867-886. doi:10.1007/s00134-021-06448-5
The complex interplay between kidney injury and inflammation
McWilliam, S. J., Wright, R. D., Welsh, G. I., Tuffin, J., Budge, K. L., Swan, L., . . . Oni, L. (n.d.). The complex interplay between kidney injury and inflammation. Clinical Kidney Journal. doi:10.1093/ckj/sfaa164
The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports
Hawcutt, D., McWilliam, S., Rodriguez-Martinez, C., Pacheco, R., Hedrich, C., Sinha, I., & Fernandes, R. (2021). The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622-1623). Retrieved from https://www.webofscience.com/
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Horby, P. W., Roddick, A., Spata, E., Staplin, N., Emberson, J., Pessoa-Amorim, G., . . . Yates, H. (2021). Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 397(10274), 605-612. doi:10.1016/S0140-6736(21)00149-5
2020
Aciclovir and acute kidney injury: putting the research in context
Sarsam, T., & McWilliam, S. J. (2020). Aciclovir and acute kidney injury: putting the research in context. ARCHIVES OF DISEASE IN CHILDHOOD, 105(12), 1206-1207. doi:10.1136/archdischild-2019-318764
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Angus, D. C., Derde, L., Al-Beidh, F., Annane, D., Arabi, Y., Beane, A., . . . Summers, C. (2020). Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.. JAMA, 324(13), 1317-1329. doi:10.1001/jama.2020.17022
G329(P) Incidence of amphotericin-induced acute kidney injury in a paediatric population: a systematic review
Mistry, D., Oni, L., & McWilliam, S. J. (2020). G329(P) Incidence of amphotericin-induced acute kidney injury in a paediatric population: a systematic review. In British association for paediatric nephrology (pp. A119.1-A119). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2020-rcpch.284
G330(P) A systematic review of the risk factors associated with vancomycin-induced acute kidney injury in children
Williams, C., Oni, L., & McWilliam, S. J. (2020). G330(P) A systematic review of the risk factors associated with vancomycin-induced acute kidney injury in children. In British association for paediatric nephrology (pp. A119.2-A119). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2020-rcpch.285
G334(P) Risk factors associated with ibuprofen induced acute kidney injury in the paediatric population: a systematic review
Cousins, S., Oni, L., & McWilliam, S. J. (2020). G334(P) Risk factors associated with ibuprofen induced acute kidney injury in the paediatric population: a systematic review. In British association for paediatric nephrology (pp. A121.1-A121). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2020-rcpch.288
G344(P) Vancomycin-induced acute kidney injury in non-critically ill children at a tertiary paediatric hospital
Redding, D. E., & McWilliam, S. J. (2020). G344(P) Vancomycin-induced acute kidney injury in non-critically ill children at a tertiary paediatric hospital. In British association for paediatric nephrology (pp. A124.1-A124). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2020-rcpch.296
Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy
McGalliard, R. J., McWilliam, S. J., Maguire, S., Jones, C. A., Jennings, R. J., Siner, S., . . . Carrol, E. D. (2020). Identifying critically ill children at high risk of acute kidney injury and renal replacement therapy. PLOS ONE, 15(10). doi:10.1371/journal.pone.0240360
A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.
McWilliam, S. J., Rosala-Hallas, A., Jones, A. P., Shaw, V., Greenhalf, W., Jaki, T., . . . Pirmohamed, M. (2020). A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.. Scientific reports, 10(1). doi:10.1038/s41598-020-58790-1
2018
Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin
McWilliam, S. J., Antoine, D. J., Jorgensen, A. L., Smyth, R. L., & Pirmohamed, M. (2018). Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin. Scientific Reports, 8. doi:10.1038/s41598-018-23466-4
Repurposing Statins for Renal Protection: Is It a Class Effect?
McWilliam, S. J., Antoine, D. J., & Pirmohamed, M. (2018). Repurposing Statins for Renal Protection: Is It a Class Effect?. CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 11(2), 100-102. doi:10.1111/cts.12521
Solving the problem of dose optimisation of children’s medicines
McWilliam, S., & Hawcutt, D. B. (2018). Solving the problem of dose optimisation of children’s medicines. Expert Review of Clinical Pharmacology, 11(3), 205-208. doi:10.1080/17512433.2018.1431528
2017
Aminoglycoside-induced nephrotoxicity in children
McWilliam, S. J., Antoine, D. J., Smyth, R. L., & Pirmohamed, M. (2017). Aminoglycoside-induced nephrotoxicity in children. Pediatric Nephrology, 32(11), 2015-2025. doi:10.1007/s00467-016-3533-z
Preventing aminoglycoside-induced nephrotoxicity using statins: an example of bench-to-bedside research
McWilliam, S. J., Antoine, D., Smyth, R., & Pirmohamed, M. (2017). Preventing aminoglycoside-induced nephrotoxicity using statins: an example of bench-to-bedside research. In Archives of Disease in Childhood Vol. 102 (pp. A12). Leuven: BMJ. Retrieved from https://adc.bmj.com/content/102/10/A17.2
THE PROTEKT STUDY - A PHASE IIA, RANDOMISED, CONTROLLED, OPEN-LABEL TRIAL OF ROSUVASTATIN FOR THE PREVENTION OF AMINOGLYCOSIDE-INDUCED KIDNEY TOXICITY IN CHILDREN WITH CYSTIC FIBROSIS
McWilliam, S. J., Antoine, D. J., Rosala-Hallas, A., Jones, A., MacLean, C., Prayle, A., . . . Pirmohamed, M. (2017). THE PROTEKT STUDY - A PHASE IIA, RANDOMISED, CONTROLLED, OPEN-LABEL TRIAL OF ROSUVASTATIN FOR THE PREVENTION OF AMINOGLYCOSIDE-INDUCED KIDNEY TOXICITY IN CHILDREN WITH CYSTIC FIBROSIS. In PEDIATRIC PULMONOLOGY Vol. 52 (pp. S353). Indiana Convention Center, Indianapolis, Indiana. doi:10.1002/ppul.23840
Optimising the use of medicines to reduce acute kidney injury in children and babies
Oni, L., Hawcutt, D. B., Turner, M. A., Beresford, M. W., McWilliam, S., Barton, C., . . . Antoine, D. J. (2017). Optimising the use of medicines to reduce acute kidney injury in children and babies. Pharmacology and Therapeutics, 174, 55-62. doi:10.1016/j.pharmthera.2017.02.018
2014
Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children
McWilliam, S. J., Antoine, D. J., Sabbisetti, V. S., Pearce, R. E., Jorgensen, A. L., Lin, Y., . . . Pirmohamed, M. (2014). Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children. Biomarkers in Medicine, 8(10), 1189-1197. doi:10.2217/bmm.14.36
66 Association of urinary kidney injury molecule-1 with aminoglycoside exposure in children with cystic fibrosis
McWilliam, S. J., Antoine, D. J., Smyth, R. L., & Pirmohamed, M. (2014). 66 Association of urinary kidney injury molecule-1 with aminoglycoside exposure in children with cystic fibrosis. Journal of Cystic Fibrosis, 13, S63. doi:10.1016/s1569-1993(14)60202-2
Quantification of Urinary Mevalonic Acid as a Biomarker of HMG-CoA Reductase Activity by a Novel Translational LC-MS/MS Method
Rodrigues, A. V. M., Maggs, J. L., McWilliam, S. J., Pirmohamed, M., Coen, M., Wilson, I. D., . . . Antoine, D. J. (2014). Quantification of Urinary Mevalonic Acid as a Biomarker of HMG-CoA Reductase Activity by a Novel Translational LC-MS/MS Method. Bioanalysis, 6(7), 919-933. doi:10.4155/bio.13.350
2012
Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study
McWilliam, S. J., Antoine, D. J., Sabbisetti, V., Turner, M. A., Farragher, T., Bonventre, J. V., . . . Pirmohamed, M. (2012). Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study. PLOS ONE, 7(8). doi:10.1371/journal.pone.0043809
2011
Measurement of the urinary biomarker KIM-1 identifies the potential for aminoglycoside-induced nephrotoxicity in premature neonates
Antoine, D. J., McWilliam, S., Sabbisetti, V., Turner, M., Smyth, R., Pirmohamed, M., . . . Park, B. K. (2011). Measurement of the urinary biomarker KIM-1 identifies the potential for aminoglycoside-induced nephrotoxicity in premature neonates. In TOXICOLOGY Vol. 290 (pp. 107). doi:10.1016/j.tox.2011.09.015
URINARY KIM-1 AS A BIOMARKER OF AMINOGLYCOSIDE-INDUCED NEPHROTOXICITY IN PREMATURE NEONATES
McWilliam, S. J., Antoine, D. J., Turner, M., Sabbisetti, V., Bonventre, J. V., Park, B. K., . . . Pirmohamed, M. (2011). URINARY KIM-1 AS A BIOMARKER OF AMINOGLYCOSIDE-INDUCED NEPHROTOXICITY IN PREMATURE NEONATES. In PEDIATRIC RESEARCH Vol. 70 (pp. 107). doi:10.1038/pr.2011.332
2010
How to use C reactive protein: postscript
McWilliam, S., & Riordan, A. (2010). How to use C reactive protein: postscript. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 95(6), 194-195. doi:10.1136/adc.2010.196287
How to use: C-reactive protein
McWilliam, S., & Riordan, A. (2010). How to use: C-reactive protein. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 95(2), 55-58. doi:10.1136/adc.2009.174367
Undated
Novel approaches to aminoglycoside-induced nephrotoxicity in children
McWilliam, S. (n.d.). Novel approaches to aminoglycoside-induced nephrotoxicity in children. (PhD Thesis, University of Liverpool).