Publications
2024
P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO).
Charras, A., Hofmann, S. R., Cox, A., Schulze, F., Russ, S., Northey, S., . . . Hedrich, C. M. (2024). P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO).. Journal of autoimmunity, 144, 103183. doi:10.1016/j.jaut.2024.103183
2023
Urinary markers of the alternative and lectin complement pathway are increased in IgA vasculitis nephritis.
Marro, J., Chetwynd, A. J., Hawkes, J., Northey, S. J., & Oni, L. (2023). Urinary markers of the alternative and lectin complement pathway are increased in IgA vasculitis nephritis.. Clinical kidney journal, 16(12), 2703-2711. doi:10.1093/ckj/sfad236
Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection
Sposito, F., Pennington, S., David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. (2023). Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection. In Airway cell biology and immunopathology (pp. OA4962). European Respiratory Society. doi:10.1183/13993003.congress-2023.oa4962
Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome.
Sposito, F., Northey, S., Charras, A., McNamara, P. S., & Hedrich, C. M. (2023). Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome.. Genes and immunity. doi:10.1038/s41435-023-00218-7
Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.
Sposito, F., Pennington, S. H., A W David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. M. (2023). Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.. Mucosal immunology, S1933-0219(23)00064-8. doi:10.1016/j.mucimm.2023.08.002
Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome
OP0100 DNA METHYLATION PATTERNS IN CD4+ T CELLS DISCERN SKIN PSORIASIS FROM PSORIATIC ARTHRITIS
Natoli, V., Charras, A., Hofmann, S., Northey, S., Russ, S., Schulze, F., . . . Hedrich, C. (2023). OP0100 DNA METHYLATION PATTERNS IN CD4+ T CELLS DISCERN SKIN PSORIASIS FROM PSORIATIC ARTHRITIS. In Scientific Abstracts (pp. 67-68). BMJ Publishing Group Ltd and European League Against Rheumatism. doi:10.1136/annrheumdis-2023-eular.4069
Urinary complement proteins are increased in children with IgA vasculitis (Henoch-Schonlein purpura) nephritis
Wright, R. D., Marro, J., Northey, S. J., Corkhill, R., Beresford, M. W., & Oni, L. (2023). Urinary complement proteins are increased in children with IgA vasculitis (Henoch-Schonlein purpura) nephritis. PEDIATRIC NEPHROLOGY, 38(5), 1491-1498. doi:10.1007/s00467-022-05747-3
DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis
Natoli, V., Charras, A., Hofmann, S. R., Northey, S., Russ, S., Schulze, F., . . . Hedrich, C. M. (n.d.). DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis. Frontiers in Immunology, 14. doi:10.3389/fimmu.2023.1245876
2022
Variations in Urinary Renin-Angiotensin-Aldosterone Component Concentrations in Paediatric IgA Vasculitis Nephritis
Chetwynd, A. J., Marro, J., Northey, S. J., Hughes, D. J., & Oni, L. (n.d.). Variations in Urinary Renin-Angiotensin-Aldosterone Component Concentrations in Paediatric IgA Vasculitis Nephritis. International Journal of Translational Medicine, 2(4), 597-606. doi:10.3390/ijtm2040045
Hypertonic saline triggers inflammatory responses in THP-1 derived macrophages
Sposito, F., Northey, S., Mcnamara, P., & Hedrich, C. (2022). Hypertonic saline triggers inflammatory responses in THP-1 derived macrophages. In EUROPEAN RESPIRATORY JOURNAL Vol. 60. doi:10.1183/13993003.congress-2022.2490
WS12.06 Hypertonic saline triggers inflammatory responses in human macrophages
Sposito, F., Northey, S., McNamara, P. S., & Hedrich, C. M. (2022). WS12.06 Hypertonic saline triggers inflammatory responses in human macrophages. Journal of Cystic Fibrosis, 21, S24. doi:10.1016/s1569-1993(22)00224-7
2021
EXPRESSION OF THE SARS-COV-2 RECEPTORS ACE2 AND TMPRSS2 IN THE RESPIRATORY TRACT OF CHILDREN AND ADULTS
Nuttall, A. G., Hedrich, C., Semple, C., Losty, P., Shukla, R., McPartland, J., . . . McNamara, P. (2021). EXPRESSION OF THE SARS-COV-2 RECEPTORS ACE2 AND TMPRSS2 IN THE RESPIRATORY TRACT OF CHILDREN AND ADULTS. In THORAX Vol. 76 (pp. A39). doi:10.1136/thorax-2021-BTSabstracts.63
Cyclic AMP Response Element Modulator-α Suppresses PD-1 Expression and Promotes Effector CD4<SUP>+</SUP> T Cells in Psoriasis
Hofmann, S. R., Carlsson, E., Kapplusch, F., Carvalho, A. L., Liloglou, T., Schulze, F., . . . Hedrich, C. M. (2021). Cyclic AMP Response Element Modulator-α Suppresses PD-1 Expression and Promotes Effector CD4<SUP>+</SUP> T Cells in Psoriasis. JOURNAL OF IMMUNOLOGY, 207(1), 55-64. doi:10.4049/jimmunol.2100240
2019
cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus
Hofmann, S. R., Mäbert, K., Kapplusch, F., Russ, S., Northey, S., Beresford, M. W., . . . Hedrich, C. M. (2019). cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus. Journal of Immunology, 203(11), 2807-2816. doi:10.4049/jimmunol.1900760
Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus
Wright, R. D., Dimou, P., Northey, S. J., & Beresford, M. W. (2019). Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus. JOURNAL OF INFLAMMATION-LONDON, 16(1). doi:10.1186/s12950-019-0227-x