Publications
2022
<i>Plasmodium falciparum</i> GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA.
Edwards-Smallbone, J., Jensen, A. L., Roberts, L. E., Totañes, F. I. G., Hart, S. R., & Merrick, C. J. (2022). <i>Plasmodium falciparum</i> GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA.. Frontiers in cellular and infection microbiology, 12, 782537. doi:10.3389/fcimb.2022.782537
2021
<i>Plasmodium falciparum</i> GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA
Edwards-Smallbone, J., Jensen, A., Roberts, L., Totanes, F. I., Hart, S., & Merrick, C. (2021). <i>Plasmodium falciparum</i> GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA. doi:10.1101/2021.07.02.450898
2020
Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen Plus<sup>TM</sup>, for protected cell therapy applications.
Finch, L., Harris, S., Solomou, G., Sen, J., Tzerakis, N., Emes, R. D., . . . Chari, D. M. (2020). Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen Plus<sup>TM</sup>, for protected cell therapy applications.. Journal of controlled release : official journal of the Controlled Release Society, 321, 553-563. doi:10.1016/j.jconrel.2020.02.028
2018
Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study.
Cao, P., Yang, Y., Uche, F. I., Hart, S. R., Li, W. -W., & Yuan, C. (2018). Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study.. International journal of molecular sciences, 19(3), E793. doi:10.3390/ijms19030793
Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease.
A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells.
Al-Mayyahi, R. S., Sterio, L. D., Connolly, J. B., Adams, C. F., Al-Tumah, W. A., Sen, J., . . . Chari, D. M. (2018). A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells.. Molecular and cellular neurosciences, 86, 30-40. doi:10.1016/j.mcn.2017.11.006
2017
Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.
de Wolf, E., Abdullah, M. I., Jones, S. M., Menezes, K., Moss, D. M., Drijfhout, F. P., . . . Richardson, A. (2017). Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.. Scientific reports, 7(1), 5410. doi:10.1038/s41598-017-05595-4
2016
Fluorescent liquid pyrene derivative-in-water microemulsions.
Hollamby, M. J., Danks, A. E., Schnepp, Z., Rogers, S. E., Hart, S. R., & Nakanishi, T. (2016). Fluorescent liquid pyrene derivative-in-water microemulsions.. Chemical communications (Cambridge, England), 52(46), 7344-7347. doi:10.1039/c6cc01517d
2015
Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides
Hart, S. R., Kenny, L. C., Myers, J. E., & Baker, P. N. (2015). Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 391, 41-46. doi:10.1016/j.ijms.2015.08.025
[203-POS]
Hart, S., Kenny, L., Myers, J., & Baker, P. (2015). [203-POS]. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 5(1), 102. doi:10.1016/j.preghy.2014.10.209
[82-OR]
Hart, S., Kenny, L., Myers, J., & Baker, P. (2015). [82-OR]. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 5(1), 44-45. doi:10.1016/j.preghy.2014.10.086
2011
Distributions of ion series in ETD and CID spectra: making a comparison.
Hart, S. R., Lau, K. W., Gaskell, S. J., & Hubbard, S. J. (2011). Distributions of ion series in ETD and CID spectra: making a comparison.. Methods in molecular biology (Clifton, N.J.), 696, 327-337. doi:10.1007/978-1-60761-987-1_21
2010
A Protocol for top-down proteomics using HPLC and ETD/PTR-MS.
Hart, S. R. (2010). A Protocol for top-down proteomics using HPLC and ETD/PTR-MS.. Methods in molecular biology (Clifton, N.J.), 658, 339-353. doi:10.1007/978-1-60761-780-8_21
2009
Observations on the detection of b- and y-type ions in the collisionally activated decomposition spectra of protonated peptides.
Lau, K. W., Hart, S. R., Lynch, J. A., Wong, S. C. C., Hubbard, S. J., & Gaskell, S. J. (2009). Observations on the detection of b- and y-type ions in the collisionally activated decomposition spectra of protonated peptides.. Rapid communications in mass spectrometry : RCM, 23(10), 1508-1514. doi:10.1002/rcm.4032
Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy.
Hart, S. R., Lau, K. W., Hao, Z., Broadhead, R., Portman, N., Hühmer, A., . . . Gaskell, S. J. (2009). Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy.. Journal of the American Society for Mass Spectrometry, 20(2), 167-175. doi:10.1016/j.jasms.2008.08.014
2008
Methods of proteome analysis: challenges and opportunities.
Hart, S. R., & Gaskell, S. J. (2008). Methods of proteome analysis: challenges and opportunities.. SEB experimental biology series, 61, 37-64.
2007
Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium
De La Luz-Hernández, K. R., Rojas-Del Calvo, L., Victores-Sarasola, S., Lage-Castellanos, A., Eyers, C., Hart, S., . . . Gaskell, S. (2007). Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium. Biotecnologia Aplicada, 24(3-4), 215-223.
Pride Wizard: generation of standards compliant quantitative proteomics data
Swainston, N., Siepen, J. A., Jones, A. R., Hart, S. R., Hermjakob, H., Jones, P., & Hubbard, S. J. (2007). Pride Wizard: generation of standards compliant quantitative proteomics data. BMC Systems Biology, 1(S1). doi:10.1186/1752-0509-1-s1-p27
Growth control of the eukaryote cell: a systems biology study in yeast.
Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., . . . Oliver, S. G. (2007). Growth control of the eukaryote cell: a systems biology study in yeast.. Journal of biology, 6(2), 4. doi:10.1186/jbiol54
An informatic pipeline for the data capture and submission of quantitative proteomic data using iTRAQ™
Siepen, J. A., Swainston, N., Jones, A. R., Hart, S. R., Hermjakob, H., Jones, P., & Hubbard, S. J. (2007). An informatic pipeline for the data capture and submission of quantitative proteomic data using iTRAQ™. PROTEOME SCIENCE, 5. doi:10.1186/1477-5956-5-4
Evidence for multiple circulating factors in preeclampsia
Myers, J. E., Hart, S., Armstrong, S., Mires, G. J., Beynon, R., Gaskell, S. J., & Baker, P. N. (2007). Evidence for multiple circulating factors in preeclampsia. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 196(3), 266-268. doi:10.1016/j.ajog.2006.10.875
2006
Flagellar motility is required for the viability of the bloodstream trypanosome.
Broadhead, R., Dawe, H. R., Farr, H., Griffiths, S., Hart, S. R., Portman, N., . . . Gull, K. (2006). Flagellar motility is required for the viability of the bloodstream trypanosome.. Nature, 440(7081), 224-227. doi:10.1038/nature04541
2005
Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol.
Barnouin, K. N., Hart, S. R., Thompson, A. J., Okuyama, M., Waterfield, M., & Cramer, R. (2005). Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol.. Proteomics, 5(17), 4376-4388. doi:10.1002/pmic.200401323
LC–tandem MS in proteome characterization
Hart, S. R., & Gaskell, S. J. (2005). LC–tandem MS in proteome characterization. TrAC Trends in Analytical Chemistry, 24(7), 566-575. doi:10.1016/j.trac.2005.04.009
2004
PEDRo: a database for storing, searching and disseminating experimental proteomics data.
Garwood, K., McLaughlin, T., Garwood, C., Joens, S., Morrison, N., Taylor, C. F., . . . Paton, N. W. (2004). PEDRo: a database for storing, searching and disseminating experimental proteomics data.. BMC genomics, 5, 68. doi:10.1186/1471-2164-5-68
The analysis of tandem mass spectrometric datasets: high-throughput investigations require high-quality validation.
Hart, S. R., & Riba-Garcia, I. (2004). The analysis of tandem mass spectrometric datasets: high-throughput investigations require high-quality validation.. Drug discovery today, 9(9), 391-392. doi:10.1016/s1359-6446(04)03030-2
2003
Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin beta-elimination and Michael addition.
Thompson, A. J., Hart, S. R., Franz, C., Barnouin, K., Ridley, A., & Cramer, R. (2003). Characterization of protein phosphorylation by mass spectrometry using immobilized metal ion affinity chromatography with on-resin beta-elimination and Michael addition.. Analytical chemistry, 75(13), 3232-3243. doi:10.1021/ac034134h
2002
Immobilized metal ion affinity chromatography for the enrichment of phosphorylated peptides: Application to the identification of phosphorylation sites in signal transduction proteins
Hart, S. R., Foukas, L. C., Shepherd, P. R., & Cramer, R. (2002). Immobilized metal ion affinity chromatography for the enrichment of phosphorylated peptides: Application to the identification of phosphorylation sites in signal transduction proteins. In Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (pp. 297-298).
Improving phosphopeptide isolation and mass spectrometric detection by IMAC with on-resin β-elimination and Michael addition
Thompson, A. J., Hart, S., Barnouin, K., & Cramer, R. (2002). Improving phosphopeptide isolation and mass spectrometric detection by IMAC with on-resin β-elimination and Michael addition. In Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (pp. 311-312).
Factors governing the solubilization of phosphopeptides retained on ferric NTA IMAC beads and their analysis by MALDI TOFMS.
Hart, S. R., Waterfield, M. D., Burlingame, A. L., & Cramer, R. (2002). Factors governing the solubilization of phosphopeptides retained on ferric NTA IMAC beads and their analysis by MALDI TOFMS.. Journal of the American Society for Mass Spectrometry, 13(9), 1042-1051. doi:10.1016/s1044-0305(02)00432-4
2000
Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells
BRUCE, L. J., WRONG, O., TOYE, A. M., YOUNG, M. T., OGLE, G., ISMAIL, Z., . . . TANNER, M. J. A. (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells. Biochemical Journal, 350(1), 41. doi:10.1042/0264-6021:3500041
Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells.
Bruce, L. J., Wrong, O., Toye, A. M., Young, M. T., Ogle, G., Ismail, Z., . . . Tanner, M. J. (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells.. The Biochemical journal, 350 Pt 1, 41-51. doi:10.1042/bj3500041