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2011

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

Lambert, J. S., Else, L. J., Jackson, V., Breiden, J., Gibbons, S., Dickinson, L., . . . Khoo, S. H. (2011). Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy. HIV Medicine, 12(3), 166-173. doi:10.1111/j.1468-1293.2010.00865.x

DOI
10.1111/j.1468-1293.2010.00865.x
Journal article

Prevalence of Potential Drug-Drug Interactions Involving Antiretroviral Drugs in a Large Kenyan Cohort

Kigen, G., Kimaiyo, S., Nyandiko, W., Faragher, B., Sang, E., Jakait, B., . . . Khoo, S. H. (2011). Prevalence of Potential Drug-Drug Interactions Involving Antiretroviral Drugs in a Large Kenyan Cohort. PLOS ONE, 6(2). doi:10.1371/journal.pone.0016800

DOI
10.1371/journal.pone.0016800
Journal article

The utility of Therapeutic Drug Monitoring (TDM) in the management of HIV infected pregnant women in receipt of lopinavir

Caswell, R. J., Phillips, D., Chaponda, M., Khoo, S. H., Taylor, G. P., Ghanem, M., . . . Lambert, J. S. (2011). The utility of Therapeutic Drug Monitoring (TDM) in the management of HIV infected pregnant women in receipt of lopinavir. Int J STD AIDS, 22, 11-14.

Journal article

2008

Association of a single-nucleotide polymorphism in the pregnane X receptor (<i>PXR</i> 63396C→T) with reduced concentrations of unboosted atazanavir

Siccardi, M., D'Avolio, A., Baietto, L., Gibbons, S., Sciandra, M., Colucci, D., . . . Owen, A. (2008). Association of a single-nucleotide polymorphism in the pregnane X receptor (<i>PXR</i> 63396C→T) with reduced concentrations of unboosted atazanavir. CLINICAL INFECTIOUS DISEASES, 47(9), 1222-1225. doi:10.1086/592304

DOI
10.1086/592304
Journal article

Factors Influencing Efavirenz and Nevirapine Plasma Concentration: Effect of Ethnicity, Weight, and Co-Medication

Stöhr, W., Back, D., Dunn, D., Sabin, C., Winston, A., Gilson, R., . . . Khoo, S. (2008). Factors Influencing Efavirenz and Nevirapine Plasma Concentration: Effect of Ethnicity, Weight, and Co-Medication. Antiviral Therapy, 13(5), 675-685.

Journal article

2006

An update on therapeutic drug monitoring for antiretroviral drugs.

Back, D., Gibbons, S., & Khoo, S. (2006). An update on therapeutic drug monitoring for antiretroviral drugs.. Therapeutic drug monitoring, 28(3), 468-473. doi:10.1097/01.ftd.0000211825.57984.41

DOI
10.1097/01.ftd.0000211825.57984.41
Journal article

2005

The use of therapeutic drug monitoring in the management of protease inhibitor-related toxicity.

Forsyth, S. F., French, P. D., Macfarlane, E., Gibbons, S. E., & Miller, R. F. (2005). The use of therapeutic drug monitoring in the management of protease inhibitor-related toxicity.. International journal of STD & AIDS, 16(2), 139-141. doi:10.1258/0956462053057602

DOI
10.1258/0956462053057602
Journal article

2004

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen

Isaac, A., Taylor, S., Cane, P., Smit, E., Gihbons, S. E., White, D. J., . . . Back, D. J. (2004). Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 54(2), 498-502. doi:10.1093/jac/dkh357

DOI
10.1093/jac/dkh357
Journal article

Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals?

Winston, A., Pozniak, A., Smith, N., Fletcher, C., Mandalia, S., Parmar, D., . . . Nelson, M. (2004). Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals?. AIDS (London, England), 18(3), 572-574. doi:10.1097/00002030-200402200-00029

DOI
10.1097/00002030-200402200-00029
Journal article

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen

Isaac, A., Taylor, S., Cane, P., Smit, E., Gibbons, S., White, D. J., . . . Back, D. (2004). Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen. J Antimicrob Chemother, 54(2), 498-502.

Journal article

2003

Pharmacokinetic drug interactions with nevirapine.

Back, D., Gibbons, S., & Khoo, S. (2003). Pharmacokinetic drug interactions with nevirapine.. Journal of acquired immune deficiency syndromes (1999), 34 Suppl 1, S8-14. doi:10.1097/00126334-200309011-00003

DOI
10.1097/00126334-200309011-00003
Journal article

Pharmacokinetic drug interactions with nevirapine

Back, D., Gibbons, S., & Khoo, S. (2003). Pharmacokinetic drug interactions with nevirapine. J Acquir Immune Defic Syndr, 34 Sup, S8-S14. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/14562853

Journal article

2002

Therapeutic drug monitoring.

Back, D., Khoo, S., & Gibbons, S. (2002). Therapeutic drug monitoring.. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 1(3), 84-85. doi:10.1177/154510970200100301

DOI
10.1177/154510970200100301
Journal article

Therapeutic drug monitoring

Back, D., Khoo, S., & Gibbons, S. (2002). Therapeutic drug monitoring. J Int Assoc Physicians AIDS Care (Chic), 1(3), 84-85.

Journal article

2001

Therapeutic drug monitoring as a tool in treating HIV infection

Khoo, S. H., Gibbons, S. E., & Back, D. J. (2001). Therapeutic drug monitoring as a tool in treating HIV infection. AIDS, 15, S171-S181. doi:10.1097/00002030-200100005-00021

DOI
10.1097/00002030-200100005-00021
Journal article

Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users

Clarke, S. M., Mulcahy, F. M., Tjia, J., Reynolds, H. E., Gibbons, S. E., Barry, M. G., & Back, D. J. (2001). Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users. CLINICAL INFECTIOUS DISEASES, 33(9), 1595-1597. doi:10.1086/322519

DOI
10.1086/322519
Journal article

Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir

Taylor, S., Back, D. J., Drake, S. M., Workman, J., Reynolds, H., Gibbons, S. E., . . . Pillay, D. (2001). Antiretroviral drug concentrations in semen of HIV-infected men: differential penetration of indinavir, ritonavir and saquinavir. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 48(3), 351-354. doi:10.1093/jac/48.3.351

DOI
10.1093/jac/48.3.351
Journal article

The role of therapeutic drug monitoring in treatment of HIV infection

Back, D. J., Khoo, S. H., Gibbons, S. E., & Merry, C. (2001). The role of therapeutic drug monitoring in treatment of HIV infection. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 52, 89S-96S. Retrieved from https://www.webofscience.com/

Journal article

The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz

Clarke, S. M., Mulcahy, F. M., Tjia, J., Reynolds, H. E., Gibbons, S. E., Barry, M. G., & Back, D. J. (2001). The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 51(3), 213-217. doi:10.1046/j.1365-2125.2001.00342.x

DOI
10.1046/j.1365-2125.2001.00342.x
Journal article

Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents

Hoggard, P. G., Lloyd, J., Khoo, S. H., Barry, M. G., Dann, L., Gibbons, S. E., . . . Back, D. J. (2001). Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 45(3), 976-980. doi:10.1128/AAC.35.3.976-980.2001

DOI
10.1128/AAC.35.3.976-980.2001
Journal article

Therapeutic drug monitoring as a tool in treating HIV infection

Khoo, S. H., Gibbons, S. E., & Back, D. J. (2001). Therapeutic drug monitoring as a tool in treating HIV infection. AIDS, 15 Sup, S171-S181. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11816166

Journal article

2000

Enoximone pharmacokinetics in infants.

Booker, P. D., Gibbons, S., Stewart, J. I., Selby, A., Wilson-Smith, E., & Pozzi, M. (2000). Enoximone pharmacokinetics in infants.. British journal of anaesthesia, 85(2), 205-210. doi:10.1093/bja/85.2.205

DOI
10.1093/bja/85.2.205
Journal article

Pharmacokinetics of Zidovudine Phosphorylation in Human Immunodeficiency Virus-Positive Thai Patients and Healthy Volunteers

Wattanagoon, Y., Na Bangchang, K., Hoggard, P. G., Khoo, S. H., Gibbons, S. E., Phiboonbhanakit, D., . . . Back, D. J. (2000). Pharmacokinetics of Zidovudine Phosphorylation in Human Immunodeficiency Virus-Positive Thai Patients and Healthy Volunteers. Antimicrobial Agents and Chemotherapy, 44(7), 1986-1989. doi:10.1128/aac.44.7.1986-1989.2000

DOI
10.1128/aac.44.7.1986-1989.2000
Journal article

Therapeutic Drug Monitoring of Antiretrovirals in Human Immunodeficiency Virus Infection

Back, D. J., Khoo, S. H., Gibbons, S. E., Barry, M. G., & Merry, C. (2000). Therapeutic Drug Monitoring of Antiretrovirals in Human Immunodeficiency Virus Infection. Therapeutic Drug Monitoring, 22(1), 122-126. doi:10.1097/00007691-200002000-00026

DOI
10.1097/00007691-200002000-00026
Journal article

Current uses and future hopes for clinical pharmacology in the management of HIV infection.

Back, D., Khoo, S., Maher, B., & Gibbons, S. (2000). Current uses and future hopes for clinical pharmacology in the management of HIV infection.. HIV medicine, 1 Suppl 2, 12-17. doi:10.1046/j.1468-1293.2000.00001.x

DOI
10.1046/j.1468-1293.2000.00001.x
Journal article

1999

Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection.

Barry, M., Mulcahy, F., Merry, C., Gibbons, S., & Back, D. (1999). Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection.. Clinical pharmacokinetics, 36(4), 289-304. doi:10.2165/00003088-199936040-00004

DOI
10.2165/00003088-199936040-00004
Journal article

1997

Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

Merry, C., Barry, M. G., Mulcahy, F., Ryan, M., Heavey, J., Tjia, J. F., . . . Back, D. J. (1997). Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS, 11(4), F29-F33. doi:10.1097/00002030-199704000-00001

DOI
10.1097/00002030-199704000-00001
Journal article

Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.

Merry, C., Mulcahy, F., Barry, M., Gibbons, S., & Back, D. (1997). Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.. AIDS (London, England), 11(2), 268-269.

Journal article

Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.

Barry, M., Gibbons, S., Back, D., & Mulcahy, F. (1997). Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.. Clinical pharmacokinetics, 32(3), 194-209. doi:10.2165/00003088-199732030-00003

DOI
10.2165/00003088-199732030-00003
Journal article

1996

The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites

Barry, M. G., Khoo, S. H., Veal, G. J., Hoggard, P. G., Gibbons, S. E., Wilkins, E. G. L., . . . Back, D. J. (1996). The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites. AIDS, 10(12), 1361-1367. doi:10.1097/00002030-199610000-00008

DOI
10.1097/00002030-199610000-00008
Journal article

1995

Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in children with HIV infection.

Gibb, D., Barry, M., Ormesher, S., Nokes, L., Seefried, M., Giaquinto, C., & Back, D. (1995). Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in children with HIV infection.. British journal of clinical pharmacology, 39(5), 527-530. doi:10.1111/j.1365-2125.1995.tb04490.x

DOI
10.1111/j.1365-2125.1995.tb04490.x
Journal article

1994

'Didanosine - a clinical and biochemical investigation'

Gibbons, S. E. (1994). 'Didanosine - a clinical and biochemical investigation'. (Master's Thesis, The University of Liverpool).

Thesis / Dissertation

PHARMACOKINETICS OF ZIDOVUDINE AND DIDEOXYINOSINE ALONE AND IN COMBINATION IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME

BARRY, M., HOWE, J. L., ORMESHER, S., BACK, D. J., BRECKENRIDGE, A. M., BERGIN, C., . . . NYE, F. (1994). PHARMACOKINETICS OF ZIDOVUDINE AND DIDEOXYINOSINE ALONE AND IN COMBINATION IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 37(5), 421-426. doi:10.1111/j.1365-2125.1994.tb05708.x

DOI
10.1111/j.1365-2125.1994.tb05708.x
Journal article

1993

METABOLISM OF DIDANOSINE (DDI) BY ERYTHROCYTES - PHARMACOKINETIC IMPLICATIONS

BARRY, M., BACK, D., ORMESHER, S., BEECHING, N., & NYE, F. (1993). METABOLISM OF DIDANOSINE (DDI) BY ERYTHROCYTES - PHARMACOKINETIC IMPLICATIONS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 36(1), 87-88. doi:10.1111/j.1365-2125.1993.tb05899.x

DOI
10.1111/j.1365-2125.1993.tb05899.x
Journal article

1992

METABOLISM OF 2',3'-DIDEOXYINOSINE (DDI) IN HUMAN BLOOD

BACK, D. J., ORMESHER, S., TJIA, J. F., & MACLEOD, R. (1992). METABOLISM OF 2',3'-DIDEOXYINOSINE (DDI) IN HUMAN BLOOD. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 33(3), 319-322. doi:10.1111/j.1365-2125.1992.tb04043.x

DOI
10.1111/j.1365-2125.1992.tb04043.x
Journal article

Pharmacokinetics and serum protein binding of 3-keto-desogestrel in women during three cycles of treatment with a low-dose combination oral contraceptive.

Kuhnz, W., al-Yacoub, G., Power, J., Ormesher, S. E., Back, D. J., & Jütting, G. (1992). Pharmacokinetics and serum protein binding of 3-keto-desogestrel in women during three cycles of treatment with a low-dose combination oral contraceptive.. Arzneimittel-Forschung, 42(9), 1142-1146.

Journal article