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2024

Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients.

Nguyen, H., Hsu, C. -C., Meeson, A., Oldershaw, R., Richardson, G., Czosseck, A., & Lundy, D. J. (2024). Differentiation, Metabolism, and Cardioprotective Secretory Functions of Human Cardiac Stromal Cells from Ischemic and Endocarditis Patients.. Stem cells and development, 33(17-18), 484-495. doi:10.1089/scd.2024.0103

DOI
10.1089/scd.2024.0103
Journal article

Inline dynamometry provides reliable measurements of quadriceps strength in healthy and ACL-reconstructed individuals and is a valid substitute for isometric electromechanical dynamometry following ACL reconstruction.

Norris, R., Morrison, S., Price, A., Pulford, S., Meira, E., O'Neill, S., . . . Oldershaw, R. A. (2024). Inline dynamometry provides reliable measurements of quadriceps strength in healthy and ACL-reconstructed individuals and is a valid substitute for isometric electromechanical dynamometry following ACL reconstruction.. The Knee, 46, 136-147. doi:10.1016/j.knee.2023.12.006

DOI
10.1016/j.knee.2023.12.006
Journal article

2023

Abstract P3162: Evaluating Cargo And Cardioprotective Effects Of Extracellular Vesicles From Human Right Atrial Appendage Mesenchymal Cells

Czosseck, A., Chen, M. M., Hsu, C. -C., Meeson, A., Oldershaw, R., & Lundy, D. (2023). Abstract P3162: Evaluating Cargo And Cardioprotective Effects Of Extracellular Vesicles From Human Right Atrial Appendage Mesenchymal Cells. Circulation Research, 133(Suppl_1). doi:10.1161/res.133.suppl_1.p3162

DOI
10.1161/res.133.suppl_1.p3162
Journal article

Application of a novel 3D porous Poly-epsilon-lysine hydrogel, Trabeculate™, to create a biomimetic structure of the trabecular meshwork of the eye

Kingston, O. A., Meeson, A., Wellings, D., Oldershaw, R., & Sheridan, C. (2023). Application of a novel 3D porous Poly-epsilon-lysine hydrogel, Trabeculate™, to create a biomimetic structure of the trabecular meshwork of the eye. In TISSUE ENGINEERING PART A Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

Glaucomatous trabecular meshwork cell-derived extracellular matrix influences differentiation of healthy adult trabecular meshwork stem cells

Kingston, O., Bilir, E. K., Fan, X. C., Oldershaw, R., Meeson, A., Wellings, D., & Sheridan, C. (2023). Glaucomatous trabecular meshwork cell-derived extracellular matrix influences differentiation of healthy adult trabecular meshwork stem cells. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A19-A20). Retrieved from https://www.webofscience.com/

Conference Paper

2022

The diagnostic accuracy of clinical tests for anterior cruciate ligament tears are comparable but the Lachman test has been previously overestimated: a systematic review and meta-analysis

Sokal, P. A., Norris, R., Maddox, T. W., & Oldershaw, R. A. (n.d.). The diagnostic accuracy of clinical tests for anterior cruciate ligament tears are comparable but the Lachman test has been previously overestimated: a systematic review and meta-analysis. Knee Surgery, Sports Traumatology, Arthroscopy. doi:10.1007/s00167-022-06898-4

DOI
10.1007/s00167-022-06898-4
Journal article

<SUP>1</SUP>H NMR Metabolite Monitoring during the Differentiation of Human Induced Pluripotent Stem Cells Provides New Insights into the Molecular Events That Regulate Embryonic Chondrogenesis

Coope, A., Ghanameh, Z., Kingston, O., Sheridan, C. M., Barrett-Jolley, R., Phelan, M. M., & Oldershaw, R. A. (2022). <SUP>1</SUP>H NMR Metabolite Monitoring during the Differentiation of Human Induced Pluripotent Stem Cells Provides New Insights into the Molecular Events That Regulate Embryonic Chondrogenesis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(16). doi:10.3390/ijms23169266

DOI
10.3390/ijms23169266
Journal article

DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS INTO THE FUNCTIONING TRABECULAR MESHWORK CELLS

Bilir, E. K., Fan, X., Oldershaw, R., & Sheridan, C. (2022). DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS INTO THE FUNCTIONING TRABECULAR MESHWORK CELLS. In TISSUE ENGINEERING PART A Vol. 28 (pp. S512-S513). Retrieved from https://www.webofscience.com/

Conference Paper

EXTRACELLULAR MATRIX CHANGES IN GLAUCOMATOUS TRABECULAR MESHWORK EFFECT THE RATE OF ADULT STEM CELL DIFFERENTIATION

Kingston, O., Sheridan, C., Oldershaw, R., Meeson, A., & Wellings, D. (2022). EXTRACELLULAR MATRIX CHANGES IN GLAUCOMATOUS TRABECULAR MESHWORK EFFECT THE RATE OF ADULT STEM CELL DIFFERENTIATION. In TISSUE ENGINEERING PART A Vol. 28 (pp. S525-S526). Retrieved from https://www.webofscience.com/

Conference Paper

2021

2020

NOVEL UNDERSTANDING OF THE PATHOGENESIS OF JUVENILE IDIOPATHIC ARTHRITIS: FOCUS ON MESENCHYMAL STEM CELLS IMPAIRMENT, SENESCENCE AND IMMUNOREGULATORY FUNCTION

Zaripova, L., Midgley, A., Christmas, S., Baildam, E., & Oldershaw, R. (2020). NOVEL UNDERSTANDING OF THE PATHOGENESIS OF JUVENILE IDIOPATHIC ARTHRITIS: FOCUS ON MESENCHYMAL STEM CELLS IMPAIRMENT, SENESCENCE AND IMMUNOREGULATORY FUNCTION. In ANNALS OF THE RHEUMATIC DISEASES Vol. 79 (pp. 479-480). doi:10.1136/annrheumdis-2020-eular.3845

DOI
10.1136/annrheumdis-2020-eular.3845
Conference Paper

2019

2018

Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm

Stevens, A., Smith, H., Garner, T., Minogue, B., Sneddon, S., Shaw, L., . . . Kimber, S. J. (2018). Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm. doi:10.1101/411439

DOI
10.1101/411439
Journal article

CHARACTERISATION OF STEM CELL POPULATIONS WITHIN NORMAL AND RUPTURED ANTERIOR CRUCIATE LIGAMENTS'

Barrow, M., Tew, S., Comerford, E., McNicholas, M., & Oldershaw, R. (2018). CHARACTERISATION OF STEM CELL POPULATIONS WITHIN NORMAL AND RUPTURED ANTERIOR CRUCIATE LIGAMENTS'. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S405-S406). doi:10.1016/j.joca.2018.02.786

DOI
10.1016/j.joca.2018.02.786
Conference Paper

2016

2015

2014

Investigating the biological response of human mesenchymal stem cells to titanium surfaces.

German, M. J., Osei-Bempong, C., Knuth, C. A., Deehan, D. J., & Oldershaw, R. A. (2014). Investigating the biological response of human mesenchymal stem cells to titanium surfaces.. Journal of orthopaedic surgery and research, 9. doi:10.1186/s13018-014-0135-y

DOI
10.1186/s13018-014-0135-y
Journal article

Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(d,l‐lactic‐co‐glycolic acid) microparticles

Rogers, C. M., Deehan, D. J., Knuth, C. A., Rose, F. R. A. J., Shakesheff, K. M., & Oldershaw, R. A. (2014). Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(d,l‐lactic‐co‐glycolic acid) microparticles. Journal of biomedical materials research. Part A, 102(11), 3872-3882. doi:10.1002/jbm.a.35063

DOI
10.1002/jbm.a.35063
Journal article

ARE UMBILICAL CORD MESENCHYMAL STEM CELLS ADVANTAGEOUS OVER BONE MARROW MESENCHYMAL STEM CELLS FOR CELL THERAPY IN ORTHOPAEDICS?

Mennan, C., Owen, S., Mayrogonatou, E., Kletsas, D., Oldershaw, R., Richardson, J., & Roberts, S. (2014). ARE UMBILICAL CORD MESENCHYMAL STEM CELLS ADVANTAGEOUS OVER BONE MARROW MESENCHYMAL STEM CELLS FOR CELL THERAPY IN ORTHOPAEDICS?. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S486-S487). doi:10.1016/j.joca.2014.02.924

DOI
10.1016/j.joca.2014.02.924
Conference Paper

Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex

Gan, E., Robson, W., Lennard, T., Pearce, S., & Oldershaw, R. (n.d.). Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex. Endocrine Abstracts. doi:10.1530/endoabs.34.oc1.2

DOI
10.1530/endoabs.34.oc1.2
Journal article

2013

Low oxygen tension is critical for the culture of human mesenchymal stem cells with strong osteogenic potential from haemarthrosis fluid.

Knuth, C. A., Clark, M. E., Meeson, A. P., Khan, S. K., Dowen, D. J., Deehan, D. J., & Oldershaw, R. A. (2013). Low oxygen tension is critical for the culture of human mesenchymal stem cells with strong osteogenic potential from haemarthrosis fluid.. Stem cell reviews and reports, 9(5), 599-608. doi:10.1007/s12015-013-9446-3

DOI
10.1007/s12015-013-9446-3
Journal article

2012

Cell sources for the regeneration of articular cartilage: the past, the horizon and the future.

Oldershaw, R. A. (2012). Cell sources for the regeneration of articular cartilage: the past, the horizon and the future.. International journal of experimental pathology, 93(6), 389-400. doi:10.1111/j.1365-2613.2012.00837.x

DOI
10.1111/j.1365-2613.2012.00837.x
Journal article

Chondrocyte protocol

Oldershaw, R. (2014). Chondrocyte protocol. StemBook. doi:10.3824/stembook.1.56.1

DOI
10.3824/stembook.1.56.1
Journal article

Production and validation of a good manufacturing practice grade human fibroblast line for supporting human embryonic stem cell derivation and culture

Prathalingam, N., Ferguson, L., Young, L., Lietz, G., Oldershaw, R., Healy, L., . . . Herbert, M. (2012). Production and validation of a good manufacturing practice grade human fibroblast line for supporting human embryonic stem cell derivation and culture. STEM CELL RESEARCH & THERAPY, 3. doi:10.1186/scrt103

DOI
10.1186/scrt103
Journal article

Keynote: Generation of skeletal hard tissues from pluripotent stem cells

Cheng, A., Kapacee, Z., Ray, S., Dilal, K. S., Oldershaw, R., Bates, N., . . . Kimber, S. (2012). Keynote: Generation of skeletal hard tissues from pluripotent stem cells. In JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Vol. 6 (pp. 249). Retrieved from https://www.webofscience.com/

Conference Paper

2010

A chemically-defined protocol for generating chondrocytes from human embryonic stem cells

Oldershaw, R., Baxter, M., Lowe, E., Bates, N., Grady, L., Soncin, F., . . . Kimber, S. (n.d.). A chemically-defined protocol for generating chondrocytes from human embryonic stem cells. Protocol Exchange. doi:10.1038/protex.2010.201

DOI
10.1038/protex.2010.201
Journal article

Directed differentiation of human embryonic stem cells toward chondrocytes.

Oldershaw, R. A., Baxter, M. A., Lowe, E. T., Bates, N., Grady, L. M., Soncin, F., . . . Kimber, S. J. (2010). Directed differentiation of human embryonic stem cells toward chondrocytes.. Nature biotechnology, 28(11), 1187-1194. doi:10.1038/nbt.1683

DOI
10.1038/nbt.1683
Journal article

Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines.

Camarasa, M. V., Kerr, R. W., Sneddon, S. F., Bates, N., Shaw, L., Oldershaw, R. A., . . . Kimber, S. J. (2010). Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines.. In vitro cellular & developmental biology. Animal, 46(3-4), 386-394. doi:10.1007/s11626-010-9291-5

DOI
10.1007/s11626-010-9291-5
Journal article

Notch signaling during chondrogenesis of human bone marrow stem cells.

Oldershaw, R. A., & Hardingham, T. E. (2010). Notch signaling during chondrogenesis of human bone marrow stem cells.. Bone, 46(2), 286-293. doi:10.1016/j.bone.2009.04.242

DOI
10.1016/j.bone.2009.04.242
Journal article

2009

The differentiation of human embryonic stem cells towards chondroprogenitors using a chemically defined step-wise protocol

Oldershaw, R., Baxter, M., Brison, D., Hardingham, T., & Kimber, S. (2009). The differentiation of human embryonic stem cells towards chondroprogenitors using a chemically defined step-wise protocol. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 90 (pp. A71-A72). Retrieved from https://www.webofscience.com/

Conference Paper

2008

Notch signaling through jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis

Oldershaw, R. A., Tew, S. R., Russell, A. M., Meade, K., Hawkins, R., McKay, T. R., . . . Hardingham, T. E. (2008). Notch signaling through jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis. STEM CELLS, 26(3), 666-674. doi:10.1634/stemcells.2007-0806

DOI
10.1634/stemcells.2007-0806
Journal article

2006

Cartilage, SOX9 and notch signals in chondrogenesis

Hardingham, T. E., Oldershaw, R. A., & Tew, S. R. (2006). Cartilage, SOX9 and notch signals in chondrogenesis. JOURNAL OF ANATOMY, 209(4), 469-480. doi:10.1111/j.1469-7580.2006.00630.x

DOI
10.1111/j.1469-7580.2006.00630.x
Journal article

Control of chondrogenesis and the assembly of cartilage matrix

Hardingham, T., Tew, S., Oldershaw, R., & Murdoch, A. (2006). Control of chondrogenesis and the assembly of cartilage matrix. In JOURNAL OF ANATOMY Vol. 209 (pp. 573). Retrieved from https://www.webofscience.com/

Conference Paper

Low-oxygen tension affects the chondrogenic potential of human mesenchymal stem cells

Oldershaw, R., & Hardingham, T. (2006). Low-oxygen tension affects the chondrogenic potential of human mesenchymal stem cells. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 87 (pp. A35). Retrieved from https://www.webofscience.com/

Conference Paper

2005

British Society for Matrix Biology Autumn Meeting 
Joint with the UK Tissue &amp; Cell Engineering Society, University of Bristol, UK

British Society for Matrix Biology Autumn Meeting 
Joint with the UK Tissue &amp; Cell Engineering Society, University of Bristol, UK (2005). In International Journal of Experimental Pathology Vol. 86. Wiley. doi:10.1111/j.0959-9673.2005.00426.x

DOI
10.1111/j.0959-9673.2005.00426.x
Conference Paper

The putative role of the notch ligand, jagged 1, in the mediation of the early events of human mesenchymal stem cell chondrogenesis

Oldershaw, R., Murdoch, A., Brennan, K., & Hardingham, T. (2005). The putative role of the notch ligand, jagged 1, in the mediation of the early events of human mesenchymal stem cell chondrogenesis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 86 (pp. A47-A48). Retrieved from https://www.webofscience.com/

Conference Paper

2004

Investigating the role of heparin sulfate proteoglycans in hereditary multiple exostoses (HME) tumourigenesis

Scholefield, Z. M., Hassell, J. R., West, L., Govindraj, P., Hecht, J. T., Rushton, G., . . . Gallagher, J. T. (2004). Investigating the role of heparin sulfate proteoglycans in hereditary multiple exostoses (HME) tumourigenesis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 85 (pp. A73-A74). doi:10.1111/j.0959-9673.2004.390an.x

DOI
10.1111/j.0959-9673.2004.390an.x
Conference Paper

2003

expansion in FGF2 promotes matrix synthesis during chondrogenic differentiation of human bone marrow mesenchymal cells without upregulating SOX9

Murdoch, A. D., Oldershaw, R. A., & Hardingham, T. E. (2003). expansion in FGF2 promotes matrix synthesis during chondrogenic differentiation of human bone marrow mesenchymal cells without upregulating SOX9. In European Cells and Materials Vol. 6 (pp. 17).

Conference Paper

Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis

Mongiat, M., Fu, J., Oldershaw, R., Greenhalgh, R., Gown, A. M., & Iozzo, R. V. (2003). Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(19), 17491-17499. doi:10.1074/jbc.M210529200

DOI
10.1074/jbc.M210529200
Journal article

2002

Cell-surface proteoglycans are differentially regulated by chondrocytes during adaptation to cell culture

Murdoch, A. D., Oldershaw, R. A., & Hardingham, T. E. (2002). Cell-surface proteoglycans are differentially regulated by chondrocytes during adaptation to cell culture. In European Cells and Materials Vol. 4 (pp. 86-87).

Conference Paper

2001

Fibroblast growth factor-binding protein is a novel partner for perlecan protein core

Mongiat, M., Otto, J., Oldershaw, R., Ferrer, F., Sato, J. D., & Iozzo, R. V. (2001). Fibroblast growth factor-binding protein is a novel partner for perlecan protein core. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(13), 10263-10271. doi:10.1074/jbc.M011493200

DOI
10.1074/jbc.M011493200
Journal article