Publications
2024
Gas Chromatography-Sensor System Aids Diagnosis of Inflammatory Bowel Disease, and Separates Crohn's from Ulcerative Colitis, in Children.
Slater, R., Tharmaratnam, K., Belnour, S., Auth, M. K. -H., Muhammed, R., Spray, C., . . . Probert, C. (2024). Gas Chromatography-Sensor System Aids Diagnosis of Inflammatory Bowel Disease, and Separates Crohn's from Ulcerative Colitis, in Children.. Sensors (Basel, Switzerland), 24(15), 5079. doi:10.3390/s24155079
Recent advances in measuring the effects of diet on gastrointestinal physiology: Sniffing luminal gases and fecal volatile organic compounds.
Thwaites, P. A., Slater, R., Probert, C., & Gibson, P. R. (2024). Recent advances in measuring the effects of diet on gastrointestinal physiology: Sniffing luminal gases and fecal volatile organic compounds.. JGH open : an open access journal of gastroenterology and hepatology, 8(8), e70006. doi:10.1002/jgh3.70006
Faecal volatile organic compounds differ according to inflammatory bowel disease sub-type, severity, and response to treatment in paediatric patients.
Belnour, S., Slater, R., Tharmaratnam, K., Karl-Heinz Auth, M., Muhammed, R., Spray, C., . . . Allen, S. (2024). Faecal volatile organic compounds differ according to inflammatory bowel disease sub-type, severity, and response to treatment in paediatric patients.. United European gastroenterology journal, 12(6), 780-792. doi:10.1002/ueg2.12603
P109 Faecal volatile organic compound detection using a gas chromatography sensor to diagnose inflammatory bowel disease in a paediatric inception cohort
Slater, R., Tharmaratnam, K., Belnour, S., Auth, M., Muhammed, R., Spray, C., . . . Probert, C. (2024). P109 Faecal volatile organic compound detection using a gas chromatography sensor to diagnose inflammatory bowel disease in a paediatric inception cohort. In Poster Presentations (pp. A116.1-A116). BMJ Publishing Group Ltd and British Society of Gastroenterology. doi:10.1136/gutjnl-2024-bsg.191
P136 Faecal volatile organic compounds (VOCs) are correlated with bacterial taxa and functional genes in paediatric Crohn’s disease
Slater, R., Frau, A., Belnour, S., Ijaz, U. Z., Allen, S., & Probert, C. (2024). P136 Faecal volatile organic compounds (VOCs) are correlated with bacterial taxa and functional genes in paediatric Crohn’s disease. In Poster Presentations (pp. A134-A135). BMJ Publishing Group Ltd and British Society of Gastroenterology. doi:10.1136/gutjnl-2024-bsg.218
2023
Faecal and urine metabolites, but not gut microbiota, may predict response to low FODMAP diet in irritable bowel syndrome
Wilson, B., Kanno, T., Slater, R., Rossi, M., Irving, P. M., Lomer, M. C., . . . Whelan, K. (2023). Faecal and urine metabolites, but not gut microbiota, may predict response to low FODMAP diet in irritable bowel syndrome. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 58(4), 404-416. doi:10.1111/apt.17609
Faecal sulcatone: a new marker of disease activity in ulcerative colitis (UC)?
Green, K., Slater, R., Belnour, S., Allen, S., & Probert, C. (2023). Faecal sulcatone: a new marker of disease activity in ulcerative colitis (UC)?. In GUT Vol. 72 (pp. A88-A89). doi:10.1136/gutjnl-2023-BSG.148
2022
Origin and Emission of Volatile Biomarkers from Feces
Slater, R., Farrow, O., George, M., & Probert, C. S. (2022). Origin and Emission of Volatile Biomarkers from Feces. In Volatile Biomarkers for Human Health (pp. 61-86). The Royal Society of Chemistry. doi:10.1039/9781839166990-00061
Investigation of urinary volatile organic compounds as novel diagnostic and surveillance biomarkers of bladder cancer
Lett, L., George, M., Slater, R., Costello, B. D. L., Ratcliffe, N., Garcia-Finana, M., . . . Probert, C. (2022). Investigation of urinary volatile organic compounds as novel diagnostic and surveillance biomarkers of bladder cancer. British Journal of Cancer. doi:10.1038/s41416-022-01785-8
The faecal metabolome and mycobiome in Parkinson's disease
De Pablo-Fernandez, E., Gebeyehu, G. G., Flain, L., Slater, R., Frau, A., Ijaz, U. Z., . . . Probert, C. (2022). The faecal metabolome and mycobiome in Parkinson's disease. Parkinsonism & Related Disorders, 95, 65-69. doi:10.1016/j.parkreldis.2022.01.005
2021
INVESTIGATION OF THE METABOLOME AND MYCOBIOME IN PARKINSON'S DISEASE
Gebeyehu, G. G., Flain, L., Slater, R., Frau, A., Probert, C., Ijaz, U., . . . Warner, T. (2021). INVESTIGATION OF THE METABOLOME AND MYCOBIOME IN PARKINSON'S DISEASE. In GUT Vol. 70 (pp. A18). doi:10.1136/gutjnl-2021-BSG.32
The Stool Volatile Metabolome of Pre-Term Babies
Frau, A., Lett, L., Slater, R., Young, G. R., Stewart, C. J., Berrington, J., . . . Probert, C. (2021). The Stool Volatile Metabolome of Pre-Term Babies. MOLECULES, 26(11). doi:10.3390/molecules26113341
O1 Faecal volatile organic compounds in paediatric inflammatory bowel disease
Belnour, S., Slater, R., Auth, M. K. H., Muhammed, R., Spray, C., Wang, D., . . . Allen, S. (2021). O1 Faecal volatile organic compounds in paediatric inflammatory bowel disease. In Plenary (pp. A1.1-A1). BMJ Publishing Group Ltd. doi:10.1136/flgastro-2021-bspghan.1
A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome of <i>Anoplocephala perfoliata</i> Infected and Non-Infected Horses: A Pilot Study
Slater, R., Frau, A., Hodgkinson, J., Archer, D., & Probert, C. (2021). A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome of <i>Anoplocephala perfoliata</i> Infected and Non-Infected Horses: A Pilot Study. ANIMALS, 11(3). doi:10.3390/ani11030755
EFFECTS OF A BOWEL PREPARATION DIET ON THE GUT MICROBIOME
Gebeyehu, G. G., Frau, A., Slater, R., Flain, L., & Probert, C. (2021). EFFECTS OF A BOWEL PREPARATION DIET ON THE GUT MICROBIOME. In GUT Vol. 70 (pp. A182-A183). doi:10.1136/gutjnl-2020-bsgcampus.348
FAECAL VOLATILE ORGANIC COMPOUNDS IN PAEDIATRIC INFLAMMATORY BOWEL DISEASE
Belnour, S., Slater, R., Auth, M. K. H., Muhammed, R., Spray, C., Wang, D., . . . Allen, S. (2021). FAECAL VOLATILE ORGANIC COMPOUNDS IN PAEDIATRIC INFLAMMATORY BOWEL DISEASE. In GUT Vol. 70 (pp. A84-A85). doi:10.1136/gutjnl-2020-bsgcampus.160
Inter-kingdom relationships in Crohn's disease explored using a multi-omics approach
Frau, A., Ijaz, U. Z., Slater, R., Jonkers, D., Penders, J., Campbell, B. J., . . . Probert, C. S. J. (2021). Inter-kingdom relationships in Crohn's disease explored using a multi-omics approach. GUT MICROBES, 13(1). doi:10.1080/19490976.2021.1930871
LONGITUDINAL ANALYSIS OF THE METABOLOME IN EARLY LIFE IN PRETERM BABIES
Frau, A., Lett, L., Berrington, J., Slater, R., Hughes, D., Embleton, N., & Probert, C. (2021). LONGITUDINAL ANALYSIS OF THE METABOLOME IN EARLY LIFE IN PRETERM BABIES. In GUT Vol. 70 (pp. A28). doi:10.1136/gutjnl-2020-bsgcampus.50
2020
Using Volatile Organic Compounds to Investigate the Effect of Oral Iron Supplementation on the Human Intestinal Metabolome
Ahmed, A., Slater, R., Lewis, S., & Probert, C. (2020). Using Volatile Organic Compounds to Investigate the Effect of Oral Iron Supplementation on the Human Intestinal Metabolome. MOLECULES, 25(21). doi:10.3390/molecules25215113
Low FODMAP diet & prebiotic β-galactooligosaccharides improve irritable bowel syndrome and response to low FODMAP is predicted by urine and faecal metabolites: a randomised controlled trial
Wilson, B., Rossi, M., Kanno, T., Hough, R., Probert, C., Parkes, G., . . . Whelan, K. (2020). Low FODMAP diet & prebiotic β-galactooligosaccharides improve irritable bowel syndrome and response to low FODMAP is predicted by urine and faecal metabolites: a randomised controlled trial. PROCEEDINGS OF THE NUTRITION SOCIETY, 79(OCE1), E19. doi:10.1017/S002966511900140X
2019
Studies of the hindgut and faecal volatile organic compound metabolome and microbiome of the horse
Slater, R. (2019, November 25). Studies of the hindgut and faecal volatile organic compound metabolome and microbiome of the horse.
Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients
Papoutsopoulou, S., Burkitt, M. D., Bergey, F., England, H., Hough, R., Schmidt, L., . . . Probert, C. S. (2019). Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients. FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.02168
CD4 T-CELL HLA-U PSEUDOGENE AT BASELINE PREDICTS CLINICAL REMISSION TO ANTI-TNF AGENTS IN ULCERATIVE COLITIS
Subramanian, S., Rainbow, L., Gemmell, M., Fang, Y., Haldenby, S., Hough, R., & Probert, C. (2019). CD4 T-CELL HLA-U PSEUDOGENE AT BASELINE PREDICTS CLINICAL REMISSION TO ANTI-TNF AGENTS IN ULCERATIVE COLITIS. In GUT Vol. 68 (pp. A64-A65). doi:10.1136/gutjnl-2019-BSGAbstracts.127
FUNGAL FUMES IN FAECES - HIDDEN CULPRITBEHINDPARKINSON'SDISEASE?AFAECAL METABOLOMICS STUDY
Gebeyehu, G. G., De Pablo-Fernandez, E., Hough, R., Probert, C., Emmanuel, A., & Warner, T. (2019). FUNGAL FUMES IN FAECES - HIDDEN CULPRITBEHINDPARKINSON'SDISEASE?AFAECAL METABOLOMICS STUDY. In GUT Vol. 68 (pp. A204). doi:10.1136/gutjnl-2019-BSGAbstracts.391
Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (vol 8, e2939, 2017)
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., Duckworth, C. A., & Pritchard, D. M. (2019). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (vol 8, e2939, 2017). CELL DEATH & DISEASE, 10. doi:10.1038/s41419-019-1534-0
A longitudinal study of the faecal microbiome and metabolome of periparturient mares
Salem, S. E., Hough, R., Probert, C., Maddox, T. W., Antczak, P., Ketley, J. M., . . . Archer, D. C. (2019). A longitudinal study of the faecal microbiome and metabolome of periparturient mares. PeerJ, 7. doi:10.7717/peerj.6687
Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice
Reade, S., Williams, J. M., Aggio, R., Duckworth, C. A., Mahalhal, A., Hough, R., . . . Probert, C. S. (2019). Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice. FASEB JOURNAL, 33(3), 3129-3136. doi:10.1096/fj.201800076RR
Macrophage-specific NF-κB activation dynamics can segregate inflammatory bowel disease patients
Papoutsopoulou, S., Burkitt, M., Bergey, F., England, H., Hough, R., Schmidt, L., . . . Probert, C. (2019). Macrophage-specific NF-κB activation dynamics can segregate inflammatory bowel disease patients. doi:10.1101/535096
Multi-omics analysis suggests an active role of fungi in Crohn's disease
Frau, A., Ijaz, U. Z., Hough, R., Campbell, B. J., Kenny, J. G., Hall, N., . . . Probert, C. S. J. (2019). Multi-omics analysis suggests an active role of fungi in Crohn's disease. In JOURNAL OF CROHNS & COLITIS Vol. 13 (pp. S545). doi:10.1093/ecco-jcc/jjy222.966
2018
Mo1049 - Low Fodmap Diet & Prebiotic β-Galactooligosaccharides Improve Irritable Bowel Syndrome with no Impact on α-Diversity and Response to Low Fodmap Diet is Predicted by Urine and Fecal Metabolites: A Randomised Controlled Trial
Wilson, B. J., Rossi, M., Kanno, T., Hough, R., Probert, C., Parkes, G. C., . . . Whelan, K. (2018). Mo1049 - Low Fodmap Diet & Prebiotic β-Galactooligosaccharides Improve Irritable Bowel Syndrome with no Impact on α-Diversity and Response to Low Fodmap Diet is Predicted by Urine and Fecal Metabolites: A Randomised Controlled Trial. Gastroenterology, 154(6), S-683. doi:10.1016/s0016-5085(18)32410-7
A comparison of sample preparation methods for extracting volatile organic compounds (VOCs) from equine faeces using HS-SPME
Hough, R., Archer, D., & Probert, C. (2018). A comparison of sample preparation methods for extracting volatile organic compounds (VOCs) from equine faeces using HS-SPME. METABOLOMICS, 14(02), 10 pages. doi:10.1007/s11306-017-1315-7
2017
Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration. CELL DEATH & DISEASE, 8. doi:10.1038/cddis.2017.332
Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.
Burkitt, M., Williams, J., Townsend, T., Hough, R., Duckworth, C., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.. Cell Death and Disease. doi:10.1101/112656