Research
Research Interest 1
CD4 T cell immunity and B cell antibody responses to vaccines and microbial pathogens including pneumococcus, staphylococcus, meningococcus and influenza; mucosal immunology; vaccine immunology, novel immunological adjuvants; immune regulation in human upper respiratory tract.
Research grants
Novel universal influenza vaccines to eliminate major influenza disease in children
SPARKS CHARITY (UK)
December 2013 - November 2015
Investigation on the roles of regulatory T cells on mucosal immunity to Streptococcus pneumoniae in children and adults
ROYAL EMBASSY OF SAUDI ARABIA
January 2011 - September 2015
Research into the use of novel universal influenza vaccines to eliminate influenza A virus-related disease from humans
BRITISH MEDICAL ASSOCIATION (UK)
September 2012 - September 2014
Investigation of novel intranasal influenza vaccines for broad immunity against influenza viruses in children.
THE GOVERNMENT PHARMACEUTICAL ORGANIZATION (THAILAND)
August 2014 - July 2018
Investigation on immunological memory to pneumococcal pilus proteins and their potential as mucosal vaccines in children
ASSOCIATION OF COMMONWEALTH UNIVERSITIES (UK)
October 2010 - September 2014
A study on immunological memory to candidate meningococcal vaccine antigens in children
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2010 - January 2011
Regulation of mucosal immunity to upper respiratory tract pathogens and vaccines by novel immunological aduvants
ROYAL EMBASSY OF SAUDI ARABIA
January 2011 - December 2013
Evaluation of pneumolysin and its derivatives as potential vaccine candidates against pneumococcal infection using a human in vitro model system.
THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)
October 2014 - September 2018
Use of an in vitro model to study novel influenza vaccines for use in children
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2011 - June 2012
A novel vaccine candidate against pneumococcal infection in children
ACTION MEDICAL RESEARCH (UK)
November 2010 - November 2012
WELLCOME VIP 2007/08
WELLCOME TRUST (UK)
October 2007 - December 2009
Research collaborations
Prof Aras Kadioglu
Immunity to pneumococcal infection
Prof Sarah Gilbert
The University of Oxford
Influenza research
Dr Nigel Cunliffe
collaboration on pneumococcal vaccine research and PhD supervision
Prof CH Toh
collaboration on bacterial sepsis research in patients
Dr Steve Gordon
on pneumococcal infection and vaccines, and on joint PhD supervision
Prof Ralph Tripp
The University of Georgia
Professor Jeremy Derrick
The University of Manchester
Professor A Craig
Professor Dlawer Ala'Aldeen
University of Nottingham
Professor Simon Foster
University of Sheffield
Dr Aras Kadioglu
University of Leicester
Professor Z Xing
McMaster University
Professor Tim Mitchell
The University of Glasgow