Publications
2024
The predictive accuracy of cardiovascular disease risk prediction tools in inflammatory arthritis and psoriasis: an observational validation study using the Clinical Practice Research Datalink.
Hughes, D. M., Coronado, J. I. C., Schofield, P., Yiu, Z. Z. N., & Zhao, S. S. (2024). The predictive accuracy of cardiovascular disease risk prediction tools in inflammatory arthritis and psoriasis: an observational validation study using the Clinical Practice Research Datalink.. Rheumatology (Oxford, England), 63(12), 3432-3441. doi:10.1093/rheumatology/kead610
Employing community Parent Champions is associated with reduced hospitalisation rates for bronchiolitis
Lee, A., Schofield, P., Hawcutt, D., Sinha, I., & Buchan, I. (2024). Employing community Parent Champions is associated with reduced hospitalisation rates for bronchiolitis. In Paediatric respiratory epidemiology (pp. PA4075). European Respiratory Society. doi:10.1183/13993003.congress-2024.pa4075
A qualitative exploration of barriers to efficient and effective structured medication reviews in primary care: Findings from the DynAIRx study.
Abuzour, A. S., Wilson, S. A., Woodall, A. A., Mair, F. S., Clegg, A., Shantsila, E., . . . Walker, L. E. (2024). A qualitative exploration of barriers to efficient and effective structured medication reviews in primary care: Findings from the DynAIRx study.. PloS one, 19(8), e0299770. doi:10.1371/journal.pone.0299770
An international study to investigate and optimise the safety of discontinuing valproate in young men and women with epilepsy: Protocol.
Mbizvo, G. K., Martin, G. P., Sperrin, M., Bonnett, L. J., Schofield, P., Buchan, I., . . . Marson, A. G. (2024). An international study to investigate and optimise the safety of discontinuing valproate in young men and women with epilepsy: Protocol.. PloS one, 19(8), e0306226. doi:10.1371/journal.pone.0306226
Risk of type 2 diabetes, MASLD and cardiovascular disease in people living with polycystic ovary syndrome.
Henney, A. E., Gillespie, C. S., Lai, J. Y. M., Schofield, P., Riley, D. R., Caleyachetty, R., . . . Cuthbertson, D. J. (2024). Risk of type 2 diabetes, MASLD and cardiovascular disease in people living with polycystic ovary syndrome.. The Journal of clinical endocrinology and metabolism, dgae481. doi:10.1210/clinem/dgae481
2023
Outcomes of first emergency admissions for alcohol-related liver disease in England over a 10-year period: retrospective observational cohort study using linked electronic databases.
Bodger, K., Mair, T., Schofield, P., Silberberg, B., Hood, S., & Fleming, K. M. (2023). Outcomes of first emergency admissions for alcohol-related liver disease in England over a 10-year period: retrospective observational cohort study using linked electronic databases.. BMJ open, 13(11), e076955. doi:10.1136/bmjopen-2023-076955
O20 Characteristics and outcomes of first emergency admissions for alcohol-related liver disease: linkage analysis of the English CPRD population, 2008–2017
Bodger, K., Mair, T., Schofield, P., Silberberg, B., Fleming, K., & Hood, S. (2023). O20 Characteristics and outcomes of first emergency admissions for alcohol-related liver disease: linkage analysis of the English CPRD population, 2008–2017. In Oral presentations (pp. A10.1-A10). BMJ Publishing Group Ltd and British Society of Gastroenterology. doi:10.1136/gutjnl-2023-bsg.19
Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells.
Steiner, I., Flores-Tellez, T. D. N. J., Mevel, R., Ali, A., Wang, P., Schofield, P., . . . Baena, E. (2023). Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells.. Cell reports, 42(4), 112377. doi:10.1016/j.celrep.2023.112377
2021
REGIONAL INEQUALITIES IN MULTIMORBIDITY WITHIN ENGLAND BETWEEN 2004 AND 2019: A DESCRIPTIVE EPIDEMIOLOGY STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK
Head, A., Fleming, K., Kypridemos, C., Schofield, P., & O'Flaherty, M. (2021). REGIONAL INEQUALITIES IN MULTIMORBIDITY WITHIN ENGLAND BETWEEN 2004 AND 2019: A DESCRIPTIVE EPIDEMIOLOGY STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 75 (pp. A69-A70). doi:10.1136/jech-2021-SSMabstracts.149
Inequalities in incident and prevalent multimorbidity in England, 2004-19: a population-based, descriptive study
Head, A., Fleming, K., Kypridemos, C., Schofield, P., Pearson-Stuttard, J., & O'Flaherty, M. (2021). Inequalities in incident and prevalent multimorbidity in England, 2004-19: a population-based, descriptive study. LANCET HEALTHY LONGEVITY, 2(8), E489-E497. doi:10.1016/S2666-7568(21)00146-X
2020
DYNAMICS OF MULTIMORBIDITY IN ENGLAND BETWEEN 2004 AND 2019: A DESCRIPTIVE EPIDEMIOLOGY STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK
Head, A., Fleming, K., Kypridemos, C., Schofield, P., & O'Flaherty, M. (2020). DYNAMICS OF MULTIMORBIDITY IN ENGLAND BETWEEN 2004 AND 2019: A DESCRIPTIVE EPIDEMIOLOGY STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 74 (pp. A14). doi:10.1136/jech-2020-SSMabstracts.29
Dynamics of multimorbidity in England between 2004 and 2019: a descriptive epidemiology study
Head, A., Fleming, K., Kypridemos, C., Schofield, P., & O'Flaherty, M. (2020). Dynamics of multimorbidity in England between 2004 and 2019: a descriptive epidemiology study. In EUROPEAN JOURNAL OF PUBLIC HEALTH Vol. 30 (pp. V301). Retrieved from https://www.webofscience.com/
OP29 Dynamics of multimorbidity in England between 2004 and 2019: a descriptive epidemiology study using the clinical practice research datalink
Head, A., Fleming, K., Kypridemos, C., Schofield, P., & O'Flaherty, M. (2020). OP29 Dynamics of multimorbidity in England between 2004 and 2019: a descriptive epidemiology study using the clinical practice research datalink. In Journal of Epidemiology and Community Health Vol. 74 (pp. A14). SSM: BMJ.
Profiling of Circulating Free DNA Using Targeted and Genome-wide Sequencing in Patients with SCLC
Mohan, S., Foy, V., Ayub, M., Leong, H. S., Schofield, P., Sahoo, S., . . . Brady, G. (2020). Profiling of Circulating Free DNA Using Targeted and Genome-wide Sequencing in Patients with SCLC. JOURNAL OF THORACIC ONCOLOGY, 15(2), 216-230. doi:10.1016/j.jtho.2019.10.007
2019
Corrigendum: Mutational signatures of DNA mismatch repair deficiency in <i>C. elegans</i> and human cancers
Meier, B., Volkova, N. V., Hong, Y., Schofield, P., Campbell, P. J., Gerstung, M., & Gartner, A. (2019). Corrigendum: Mutational signatures of DNA mismatch repair deficiency in <i>C. elegans</i> and human cancers. Genome Research, 29(9), 1566_2. doi:10.1101/gr.255596.119
Hypoxia Induces Rapid Changes to Histone Methylation and Reprograms Chromatin
Batie, M., Frost, J., Frost, M., Wilson, J. W., Schofield, P., & Rocha, S. (2019). Hypoxia Induces Rapid Changes to Histone Methylation and Reprograms Chromatin. Science, 363(6432), 1222-1226. doi:10.1126/science.aau5870
Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response: Supplementary material
Batie, M., Frost, J., Frost, M., Wilson, J., Schofield, P., & Rocha, S. (2019). Hypoxia induces rapid changes to histone methylation reprogramming chromatin for the cellular response: Supplementary material. doi:10.1101/513069
2018
Abstract 5602: Detection of circulating cell-free tumor DNA (ctDNA) in patients with small cell lung cancer (SCLC)
Mohan, S., Foy, V., Leong, H. S., Schofield, P. G., Ayub, M., Smith, N. K., . . . Brady, G. (2018). Abstract 5602: Detection of circulating cell-free tumor DNA (ctDNA) in patients with small cell lung cancer (SCLC). Cancer Research, 78(13_Supplement), 5602. doi:10.1158/1538-7445.am2018-5602
Mutational signatures of DNA mismatch repair deficiency in C. <i>elegans</i> and human cancers
Meier, B., Volkova, N. V., Hong, Y., Schofield, P., Campbell, P. J., Gerstung, M., & Gartner, A. (2018). Mutational signatures of DNA mismatch repair deficiency in C. <i>elegans</i> and human cancers. GENOME RESEARCH, 28(5), 666-675. doi:10.1101/gr.226845.117
2017
The application of liquid biopsies in metastatic salivary gland cancer to identify candidate therapeutic targets
Metcalf, R., Mohan, S., Hilton, S., Pierce, J., Hudson, J., Betts, G., . . . Dive, C. (2017). The application of liquid biopsies in metastatic salivary gland cancer to identify candidate therapeutic targets. Annals of Oncology, 28, vii8. doi:10.1093/annonc/mdx508.016
Mutational signatures of DNA mismatch repair deficiency in<i>C. elegans</i>and human cancers
Examining the role of individual movement in promoting coexistence in a spatially explicit prisoner's dilemma
Burgess, A. E. F., Lorenzi, T., Schofield, P. G., Hubbard, S. F., & Chaplain, M. A. J. (2017). Examining the role of individual movement in promoting coexistence in a spatially explicit prisoner's dilemma. JOURNAL OF THEORETICAL BIOLOGY, 419, 323-332. doi:10.1016/j.jtbi.2017.02.028
2016
What's in a name? Word inflation, punctuation, abbreviation and cloud formation
Schofield, S. J., & Schofield, P. G. (2016). What's in a name? Word inflation, punctuation, abbreviation and cloud formation. MEDICAL EDUCATION, 50(12), 1264-1268. doi:10.1111/medu.13099
Dynamical patterns of coexisting strategies in a hybrid discrete-continuum spatial evolutionary game model
Erratum: How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?
Schurch, N. J., Schofield, P., Gierliński, M., Cole, C., Sherstnev, A., Singh, V., . . . Barton, G. J. (2016). Erratum: How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?. RNA (New York, N.Y.), 22(10), 1641. doi:10.1261/rna.058339.116
How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?
Schurch, N. J., Schofield, P., Gierlinski, M., Cole, C., Sherstnev, A., Singh, V., . . . Barton, G. J. (2016). How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?. RNA, 22(6), 839-851. doi:10.1261/rna.053959.115
The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors
Wiechens, N., Singh, V., Gkikopoulos, T., Schofield, P., Rocha, S., & Owen-Hughes, T. (2016). The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors. PLOS GENETICS, 12(3). doi:10.1371/journal.pgen.1005940
Dynamical Patterns of Coexisting Strategies in a Hybrid Discrete-continuum Spatial Evolutionary Game Model
Burgess, A. E. F., Sehofield, P. G., Hubbard, S. F., Chaplain, M. A. J., & Lorenzi, T. (2016). Dynamical Patterns of Coexisting Strategies in a Hybrid Discrete-continuum Spatial Evolutionary Game Model. MATHEMATICAL MODELLING OF NATURAL PHENOMENA, 11(5), 49-64. doi:10.1051/mmnp/201611504
2015
Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
Gierlinski, M., Cole, C., Schofield, P., Schurch, N. J., Sherstnev, A., Singh, V., . . . Barton, G. J. (2015). Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment. BIOINFORMATICS, 31(22), 3625-3630. doi:10.1093/bioinformatics/btv425
Proteotoxic stress reprograms the chromatin landscape of SUMO modification
Seifert, A., Schofield, P., Barton, G. J., & Hay, R. T. (2015). Proteotoxic stress reprograms the chromatin landscape of SUMO modification. SCIENCE SIGNALING, 8(384). doi:10.1126/scisignal.aaa2213
Evaluation of tools for differential gene expression analysis by RNA-seq on a 48 biological replicate experiment
Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
2012
Directed terminal restriction analysis tool (DRAT): an aid to enzyme selection for directed terminal-restriction fragment length polymorphisms
Roberts, D. M., Schofield, P. G., Donn, S., & Daniell, T. J. (2012). Directed terminal restriction analysis tool (DRAT): an aid to enzyme selection for directed terminal-restriction fragment length polymorphisms. METHODS IN ECOLOGY AND EVOLUTION, 3(1), 24-28. doi:10.1111/j.2041-210X.2011.00139.x
2011
A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization
Gkikopoulos, T., Schofield, P., Singh, V., Pinskaya, M., Mellor, J., Smolle, M., . . . Owen-Hughes, T. (2011). A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization. SCIENCE, 333(6050), 1758-1760. doi:10.1126/science.1206097
2010
High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli
van Koningsbruggen, S., Gierlinski, M., Schofield, P., Martin, D., Barton, G. J., Ariyurek, Y., . . . Lamond, A. I. (2010). High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli. MOLECULAR BIOLOGY OF THE CELL, 21(21), 3735-3748. doi:10.1091/mbc.E10-06-0508
Modelling contact spread of infection in host-parasitoid systems: Vertical transmission of pathogens can cause chaos
Preedy, K. F., Schofield, P. G., Liu, S., Matzavinos, A., Chaplain, M. A. J., & Hubbard, S. F. (2010). Modelling contact spread of infection in host-parasitoid systems: Vertical transmission of pathogens can cause chaos. JOURNAL OF THEORETICAL BIOLOGY, 262(3), 441-451. doi:10.1016/j.jtbi.2009.10.003
2009
Gender Variance in the UK: Prevalence, Incidence Growth and Geographic Distribution.
Reed, B., Rhodes, S., Schofield, P., & Wylie, K. (2009). Gender Variance in the UK: Prevalence, Incidence Growth and Geographic Distribution.. GIRES Technical Report.
2008
Enhancing the Quality of Hardy Nursery Stock and Sustainability of the Industry through Novel Water-Saving Techniques
Davies, W. J., Bacon, M. A., Sharp, R. G., Jones, H. G., Schofield, P. G., Atkinson, C. J., . . . York, M. (2008). Enhancing the Quality of Hardy Nursery Stock and Sustainability of the Industry through Novel Water-Saving Techniques. Horticultural Development Company.
Thermal and Other Remote Sensing of Plant Stress.
Jones, H., & Schofield, P. (2008). Thermal and Other Remote Sensing of Plant Stress.. General Applications Plant Physiology.
2007
Chemotaxis-induced spatio-temporal heterogeneity in multi-species host-parasitoid systems
Pearce, I. G., Chaplain, M. A. J., Schofield, P. G., Anderson, A. R. A., & Hubbard, S. F. (2007). Chemotaxis-induced spatio-temporal heterogeneity in multi-species host-parasitoid systems. JOURNAL OF MATHEMATICAL BIOLOGY, 55(3), 365-388. doi:10.1007/s00285-007-0088-4
Disease induced dynamics in host-parasitoid systems: chaos and coexistence
Preedy, K. F., Schofield, P. G., Chaplain, M. A. J., & Hubbard, S. F. (2007). Disease induced dynamics in host-parasitoid systems: chaos and coexistence. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 4(14), 463-471. doi:10.1098/rsif.2006.0184
2006
Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: Heterogeneous patterns and ecological implications
Pearce, I. G., Chaplain, M. A. J., Schofield, P. G., Anderson, A. R. A., & Hubbard, S. F. (2006). Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: Heterogeneous patterns and ecological implications. JOURNAL OF THEORETICAL BIOLOGY, 241(4), 876-886. doi:10.1016/j.jtbi.2006.01.026
<i>Wolbachia</i> infection suppresses both host defence and parasitoid counter-defence
Fytrou, A., Schofield, P. G., Kraaijeveld, A. R., & Hubbard, S. F. (2006). <i>Wolbachia</i> infection suppresses both host defence and parasitoid counter-defence. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 273(1588), 791-796. doi:10.1098/rspb.2005.3383
2005
Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations
Schofield, P., Chaplain, M., & Hubbard, S. (2005). Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations. JOURNAL OF THEORETICAL BIOLOGY, 237(1), 1-16. doi:10.1016/j.jtbi.2005.03.025
Dynamic heterogeneous spatio-temporal pattern formation in host-parasitoid systems with synchronised generations
Schofield, P. G., Chaplain, M. A. J., & Hubbard, S. F. (2005). Dynamic heterogeneous spatio-temporal pattern formation in host-parasitoid systems with synchronised generations. JOURNAL OF MATHEMATICAL BIOLOGY, 50(5), 559-583. doi:10.1007/s00285-004-0298-y
2002
Spatially explicit models of Turelli-Hoffmann <i>Wolbachia</i> invasive wave fronts
Schofield, P. (2002). Spatially explicit models of Turelli-Hoffmann <i>Wolbachia</i> invasive wave fronts. JOURNAL OF THEORETICAL BIOLOGY, 215(1), 121-131. doi:10.1006/jtbi.2001.2493
Mathematical modelling of host-parasitoid systems: Effects of chemically mediated parasitoid foraging strategies on within- and between-generation spatio-temporal dynamics
Schofield, P., Chaplain, M., & Hubbard, S. (2002). Mathematical modelling of host-parasitoid systems: Effects of chemically mediated parasitoid foraging strategies on within- and between-generation spatio-temporal dynamics. JOURNAL OF THEORETICAL BIOLOGY, 214(1), 31-47. doi:10.1006/jtbi.2001.2418
Spatio-Temporal Mathematical Models for the Investigation of Host-Parasitoid Systems and Wolbachia-Infection Dynamics
Schofield, P. G. (2002). Spatio-Temporal Mathematical Models for the Investigation of Host-Parasitoid Systems and Wolbachia-Infection Dynamics. (PhD Thesis, University of Dundee).
2000
Spatio-Temporal Mathematical Models of Host-Parasitoid Systems
Schofield, P., Chaplain, M. A. J., & Hubbard, S. F. (2000). Spatio-Temporal Mathematical Models of Host-Parasitoid Systems. European Communications of Mathematical and Theoretical Biology, 2.
Undated
Risk of Type 2 Diabetes, Metabolic Dysfunction Associated Steatotic Liver Disease and Cardiovascular Disease in People Living with Polycystic Ovary Syndrome According to Disease Phenotype: An Analysis of Prospective Cohort and Multi-Organ Imaging Data from the UK Biobank
Henney, A. E., Gillespie, C. S., Lai, J. Y. M., Schofield, P., Riley, D., Caleyachetty, R., . . . Cuthbertson, D. J. (n.d.). Risk of Type 2 Diabetes, Metabolic Dysfunction Associated Steatotic Liver Disease and Cardiovascular Disease in People Living with Polycystic Ovary Syndrome According to Disease Phenotype: An Analysis of Prospective Cohort and Multi-Organ Imaging Data from the UK Biobank.