Publications
2024
The low-density lipoprotein receptor-related protein 1 regulates non-canonical Wnt signalling and its deficiency causes severe and multiple skeletal defects.
Gremida, A., Wheeler, G., Yamamoto, K., Bou-Gharios, G., Clegg, P., Hof, R. V. T., . . . Maharana, S. (2024). The low-density lipoprotein receptor-related protein 1 regulates non-canonical Wnt signalling and its deficiency causes severe and multiple skeletal defects.. Osteoarthritis and Cartilage, 32(6), 812. doi:10.1016/j.joca.2024.03.078
The Interfascicular Matrix of Energy Storing Tendons Houses Heterogenous Cell Populations Disproportionately Affected by Aging
Zamboulis, D. E., Marr, N., Lenzi, L., Birch, H. L., Screen, H. R. C., Clegg, P. D., & Thorpe, C. T. (2024). The Interfascicular Matrix of Energy Storing Tendons Houses Heterogenous Cell Populations Disproportionately Affected by Aging. AGING AND DISEASE. doi:10.14336/AD.2023.0425-1
Current clinical opinion on surgical approaches and rehabilitation of hand flexor tendon injury-a questionnaire study.
Xue, R., Wong, J., Imere, A., King, H., Clegg, P., & Cartmell, S. (2024). Current clinical opinion on surgical approaches and rehabilitation of hand flexor tendon injury-a questionnaire study.. Frontiers in medical technology, 6, 1269861. doi:10.3389/fmedt.2024.1269861
2023
MicroRNA Signatures in Cartilage Ageing and Osteoarthritis
Balaskas, P., Goljanek-Whysall, K., Clegg, P. D., Fang, Y., Cremers, A., Smagul, A., . . . Peffers, M. J. (2023). MicroRNA Signatures in Cartilage Ageing and Osteoarthritis. BIOMEDICINES, 11(4). doi:10.3390/biomedicines11041189
2022
Ex vivo study correlating the stiffness of the ovine patellar tendon to age and weight.
Kayser, F., Bori, E., Fourny, S., Hontoir, F., Clegg, P., Dugdale, A., . . . Innocenti, B. (2022). Ex vivo study correlating the stiffness of the ovine patellar tendon to age and weight.. International biomechanics, 9(1), 1-9. doi:10.1080/23335432.2022.2108899
UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty
Harvey, N. C., Clegg, P. D., Dennison, E. M., Greenhaff, P., Griffin, S. J., Gregson, C. L., . . . Cooper, C. (2022). UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty. ARCHIVES OF OSTEOPOROSIS, 17(1). doi:10.1007/s11657-022-01172-z
Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice
Lee, K. J., Rambault, L., Bou-Gharios, G., Clegg, P. D., Akhtar, R., Czanner, G., . . . Canty-Laird, E. G. (2022). Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice. DISEASE MODELS & MECHANISMS, 15(9). doi:10.1242/dmm.049428
Antimicrobial resistance in clinical bacterial isolates from horses in the UK
Isgren, C. M., Williams, N. J., Fletcher, O. D., Timofte, D., Newton, R. J., Maddox, T. W., . . . Pinchbeck, G. L. (2022). Antimicrobial resistance in clinical bacterial isolates from horses in the UK. EQUINE VETERINARY JOURNAL, 54(2), 390-414. doi:10.1111/evj.13437
Gene expression analysis of subchondral bone, cartilage, and synovium in naturally occurring equine palmar/plantar osteochondral disease
Turlo, A. J., McDermott, B. T., Barr, E. D., Riggs, C. M., Boyde, A., Pinchbeck, G. L., & Clegg, P. D. (2022). Gene expression analysis of subchondral bone, cartilage, and synovium in naturally occurring equine palmar/plantar osteochondral disease. JOURNAL OF ORTHOPAEDIC RESEARCH, 40(3), 595-603. doi:10.1002/jor.25075
2021
Equine flexor tendon imaging part 1: Recent developments in ultrasonography, with focus on the superficial digital flexor tendon
Ehrle, A., Lilge, S., Clegg, P. D., & Maddox, T. W. (2021). Equine flexor tendon imaging part 1: Recent developments in ultrasonography, with focus on the superficial digital flexor tendon. VETERINARY JOURNAL, 278. doi:10.1016/j.tvjl.2021.105764
Equine flexor tendon imaging part 2: Current status and future directions in advanced diagnostic imaging, with focus on the deep digital flexor tendon
Ehrle, A., Lilge, S., Clegg, P. D., & Maddox, T. W. (2021). Equine flexor tendon imaging part 2: Current status and future directions in advanced diagnostic imaging, with focus on the deep digital flexor tendon. VETERINARY JOURNAL, 278. doi:10.1016/j.tvjl.2021.105763
miR-24 and its target gene Prdx6 regulate viability and senescence of myogenic progenitors during aging
Soriano-Arroquia, A., Gostage, J., Xia, Q., Bardell, D., McCormick, R., McCloskey, E., . . . Goljanek-Whysall, K. (2021). miR-24 and its target gene Prdx6 regulate viability and senescence of myogenic progenitors during aging. AGING CELL, 20(10). doi:10.1111/acel.13475
Structure-function specialisation of the interfascicular matrix in the human achilles tendon
Patel, D., Zamboulis, D. E., Spiesz, E. M., Birch, H. L., Clegg, P. D., Thorpe, C. T., & Screen, H. R. C. (2021). Structure-function specialisation of the interfascicular matrix in the human achilles tendon. ACTA BIOMATERIALIA, 131, 381-390. doi:10.1016/j.actbio.2021.07.019
The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments
Kharaz, Y. A., Birch, H., Chester, A., Alchorne, E., Simpson, D., Clegg, P., & Comerford, E. (2021). The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 31(11), 2033-2043. doi:10.1111/sms.14023
Characterisation of key proteoglycans in the cranial cruciate ligaments (CCLs) from two dog breeds with different predispositions to CCL disease and rupture.
Allaith, S., Tew, S. R., Hughes, C. E., Clegg, P. D., Canty-Laird, E. G., & Comerford, E. J. (2021). Characterisation of key proteoglycans in the cranial cruciate ligaments (CCLs) from two dog breeds with different predispositions to CCL disease and rupture.. Veterinary journal (London, England : 1997), 272, 105657. doi:10.1016/j.tvjl.2021.105657
Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis
Castanheira, C. I. G. D., Anderson, J. R., Fang, Y., Milner, P. I., Goljanek-Whysall, K., House, L., . . . Peffers, M. J. (2021). Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis. Osteoarthritis and Cartilage Open, 100186. doi:10.1016/j.ocarto.2021.100186
SYNOVIAL FLUID AND SERUM SMALL NON-CODING RNA SIGNATURES IN EQUINE OSTEOARTHRITIS
Castanheira, C., James, V., Taylor, S., Skioldebrand, E., Clegg, P. D., & Peffers, M. J. (2021). SYNOVIAL FLUID AND SERUM SMALL NON-CODING RNA SIGNATURES IN EQUINE OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S162). Retrieved from https://www.webofscience.com/
Intra-Fascicular Chondroid-like Bodies in the Ageing Equine Superficial Digital Flexor Tendon comprise Glycosaminoglycans and Type II Collagen.
Ali, O. J., Ehrle, A., Comerford, E. J., Canty-Laird, E. G., Mead, A., Clegg, P. D., & Maddox, T. W. (2021). Intra-Fascicular Chondroid-like Bodies in the Ageing Equine Superficial Digital Flexor Tendon comprise Glycosaminoglycans and Type II Collagen.. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. doi:10.1002/jor.25002
Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
Castanheira, C., Balaskas, P., Falls, C., Ashraf-Kharaz, Y., Clegg, P., Burke, K., . . . Peffers, M. J. (2021). Equine synovial fluid small non-coding RNA signatures in early osteoarthritis. BMC VETERINARY RESEARCH, 17(1). doi:10.1186/s12917-020-02707-7
2020
Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix
Zamboulis, D. E., Thorpe, C. T., Ashraf Kharaz, Y., Birch, H. L., Screen, H. R. C., & Clegg, P. D. (n.d.). Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix. eLife, 2020(9). doi:10.7554/elife.58075
Epigenetic mechanisms in tendon ageing
Riasat, K., Bardell, D., Goljanek-Whysall, K., Clegg, P., & Peffers, M. (n.d.). Epigenetic mechanisms in tendon ageing. British Medical Bulletin. doi:10.1093/bmb/ldaa023
Is the T-ligament a ligament? A histological study in equine cadaver forelimbs.
Hontoir, F., Paques, F., Simon, V., Balau, B., Nicaise, C., Clegg, P., . . . Vandeweerd, J. M. (2020). Is the T-ligament a ligament? A histological study in equine cadaver forelimbs.. Research in veterinary science, 132, 10-16. doi:10.1016/j.rvsc.2020.05.018
Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study.
Anderson, J. R., Phelan, M. M., Foddy, L., Clegg, P. D., & Peffers, M. J. (2020). Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study.. Journal of proteome research. doi:10.1021/acs.jproteome.0c00143
Active synthesis of type I collagen homotrimer in Dupuytren’s fibrosis is unaffected by anti-TNF-α treatment
Williamson, K., Lee, K., Beamish, E., Carter, A., Gumbs, J., Cooper, G., . . . Canty-Laird, E. (2020). Active synthesis of type I collagen homotrimer in Dupuytren’s fibrosis is unaffected by anti-TNF-α treatment. doi:10.1101/2020.07.13.195107
Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice
Lee, K., Rambault, L., Bou-Gharios, G., Clegg, P., Akhtar, R., Czanner, G., . . . Canty-Laird, E. (2020). Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice. doi:10.1101/2020.07.13.198283
Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics
Anderson, J. R., Phelan, M. M., Rubio-Martinez, L. M., Fitzgerald, M. M., Jones, S. W., Clegg, P. D., & Peffers, M. J. (2020). Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics. Journal of Proteome Research, 19(7), 2585-2597. doi:10.1021/acs.jproteome.0c00035
Heterogeneity of proteome dynamics between connective tissue phases of adult tendon
Choi, H., Simpson, D., Wang, D., Prescott, M., Pitsillides, A. A., Dudhia, J., . . . Thorpe, C. T. (2020). Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. eLife, 9. doi:10.7554/elife.55262
Metabolomic and Proteomic Stratification of Equine Osteoarthritis
Anderson, J., Phelan, M., Caamaño-Gutiérrez, E., Clegg, P., Rubio-Martinez, L., & Peffers, M. (2020). Metabolomic and Proteomic Stratification of Equine Osteoarthritis. doi:10.1101/2020.05.04.077305
Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis.
Lo Monaco, M., Gervois, P., Beaumont, J., Clegg, P., Bronckaers, A., Vandeweerd, J. -M., & Lambrichts, I. (2020). Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis.. Cells, 9(4), E980. doi:10.3390/cells9040980
THE EFFECT OF EXERCISE ON THE PROTEIN PROFILE OF RAT KNEE JOINT INTRA- AND EXTRA-ARTICULAR LIGAMENTS
Kharaz, Y. A., Birch, H., Allchorne, E., Chesten, A., Clegg, P., & Comerford, E. (2018). THE EFFECT OF EXERCISE ON THE PROTEIN PROFILE OF RAT KNEE JOINT INTRA- AND EXTRA-ARTICULAR LIGAMENTS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S171). doi:10.1016/j.joca.2018.02.371
2019
Insulin-like growth factor binding protein (IGFBP6) is a cross-species tendon marker.
Turlo, A. J., Mueller-Breckenridge, A. J., Zamboulis, D. E., Tew, S. R., Canty-Laird, E. G., & Clegg, P. D. (2019). Insulin-like growth factor binding protein (IGFBP6) is a cross-species tendon marker.. European Cells and Materials, 38, 123-136. doi:10.22203/ecm.v038a10
Emergence of carriage of CTX-M-15 in faecal Escherichia coli in horses at an equine hospital in the UK; increasing prevalence over a decade (2008-2017))
Isgren, C. M., Edwards, T., Pinchbeck, G. L., Winward, E., Adams, E. R., Norton, P., . . . Williams, N. J. (2019). Emergence of carriage of CTX-M-15 in faecal Escherichia coli in horses at an equine hospital in the UK; increasing prevalence over a decade (2008-2017)). BMC VETERINARY RESEARCH, 15. doi:10.1186/s12917-019-2011-9
Age-related morphometric changes of the tidemark in the ovine stifle.
Hontoir, F., Pirson, R., Simon, V., Clegg, P., Nisolle, J. -F., Kirschvink, N., & Vandeweerd, J. -M. E. (2019). Age-related morphometric changes of the tidemark in the ovine stifle.. Anatomia, histologia, embryologia, 48(4), 366-374. doi:10.1111/ahe.12449
The synovial fluid proteome differentiates between septic and nonseptic articular pathologies
Anderson, J. R., Smagul, A., Simpson, D., Clegg, P. D., Rubio-Martinez, L. M., & Peffers, M. J. (2019). The synovial fluid proteome differentiates between septic and nonseptic articular pathologies. JOURNAL OF PROTEOMICS, 202. doi:10.1016/j.jprot.2019.04.020
Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography
Hontoir, F., Rejas, E., Falticeanu, A., Nisolle, J. -F., Simon, V., Nicaise, C., . . . Vandeweerd, J. -M. E. (2019). Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography. ANATOMIA HISTOLOGIA EMBRYOLOGIA, 48(2), 133-141. doi:10.1111/ahe.12421
Identification and Characterization of Canine Ligament Progenitor Cells and Their Extracellular Matrix Niche
Lee, K. J., Comerford, E. J., Simpson, D. M., Clegg, P. D., & Canty-Laird, E. G. (2019). Identification and Characterization of Canine Ligament Progenitor Cells and Their Extracellular Matrix Niche. Journal of Proteome Research, 18(3), 1328-1339. doi:10.1021/acs.jproteome.8b00933
Insulin-like growth factor binding protein 6 (<i>Igfbp6</i>) as a gene expression marker of normal tendon phenotype in native tissue and cell culture systems
Turlo, A. J., Mueller-Breckenridge, A. J., Zamboulis, D., Millar, N. L., Akbar, M., Laird, E., . . . Clegg, P. D. (2019). Insulin-like growth factor binding protein 6 (<i>Igfbp6</i>) as a gene expression marker of normal tendon phenotype in native tissue and cell culture systems. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A40-A41). Retrieved from https://www.webofscience.com/
Morphometric Measurements of the Equine Hoof: How is Hoof Shape Altered by Trimming?
Harley, S. L., Milner, P. I., Clegg, P. D., Pinchbeck, G. L., & Ireland, J. I. (2019). Morphometric Measurements of the Equine Hoof: How is Hoof Shape Altered by Trimming?. In JOURNAL OF MORPHOLOGY Vol. 280 (pp. S132-S133). Retrieved from https://www.webofscience.com/
2018
Insulin-like growth factor binding protein (Igfbp6) is a cross-species transcriptomic tendon marker
Mueller-Breckenridge, A. J., Turlo, A. J., Zamboulis, D., Peffers, M. J., & Clegg, P. D. (2018). Insulin-like growth factor binding protein (Igfbp6) is a cross-species transcriptomic tendon marker. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A2-A3). Retrieved from https://www.webofscience.com/
Clinical insights: Recent developments in equine articular disease (2016-2018)
Clegg, P. (2018). Clinical insights: Recent developments in equine articular disease (2016-2018). EQUINE VETERINARY JOURNAL, 50(6), 705-707. doi:10.1111/evj.13016
Towards a toolkit for the assessment and monitoring of musculoskeletal ageing
Kemp, G. J., Jackson, M. J., Mccloskey, E. V., & Mathers, J. C. (2018). Towards a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(6), 774-777. doi:10.1093/ageing/afy078
Developing a toolkit for the assessment and monitoring of musculoskeletal ageing
Kemp, G. J., Birrell, F., Clegg, P. D., Cuthbertson, D. J., De Vito, G., van Dieen, J. H., . . . Mathers, J. C. (2018). Developing a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(suppl_4), iv1-iv19. doi:10.1093/ageing/afy143
Stratifying osteoarthritis using liquid chromatography‐tandem mass spectrometry proteomic analysis of synovial fluid
Stratifying osteoarthritis using liquid chromatography‐tandem mass spectrometry proteomic analysis of synovial fluid (2018). In Equine Veterinary Journal Vol. 50 (pp. 26-27). Wiley. doi:10.1111/evj.48_13008
Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies
Anderson, J. R., Phelan, M. M., Clegg, P. D., Peffers, M. J., & Rubio-Martinez, L. M. (2018). Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies. Journal of Proteome Research, 17(8), 2735-2743. doi:10.1021/acs.jproteome.8b00190
Avulsion of the proximal digital annular ligament in five hindlimbs
O'Brien, E. J. O., McAlpine, J. M., Schramme, M. C., Clegg, P. D., Archer, R. M., De Guio, C., & Smith, R. K. W. (2018). Avulsion of the proximal digital annular ligament in five hindlimbs. EQUINE VETERINARY EDUCATION, 30(8), 427-432. doi:10.1111/eve.12861
A comparison of the stem cell characteristics of murine tenocytes and tendon-derived stem cells
Lee, K. J., Clegg, P. D., Comerford, E. J., & Canty-Laird, E. G. (2018). A comparison of the stem cell characteristics of murine tenocytes and tendon-derived stem cells. BMC MUSCULOSKELETAL DISORDERS, 19. doi:10.1186/s12891-018-2038-2
PRE- AND POST-NATAL DEVELOPMENT OF THE TENDON INTER-FASCICULAR MATRIX AND FASCICLES IN THE EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON AND COMMON DIGITAL EXTENSOR TENDON
Zamboulis, D. E., Thorpe, C. T., Birch, H. L., Screen, H. R., & Clegg, P. D. (2018). PRE- AND POST-NATAL DEVELOPMENT OF THE TENDON INTER-FASCICULAR MATRIX AND FASCICLES IN THE EQUINE SUPERFICIAL DIGITAL FLEXOR TENDON AND COMMON DIGITAL EXTENSOR TENDON. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S403-S404). doi:10.1016/j.joca.2018.02.783
STRATIFYING OSTEOARTHRITIS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY PROTEOMIC ANALYSIS OF SYNOVIAL FLUID
Anderson, J. R., Clegg, P. D., Rubio-Martinez, L. M., Riggs, C. M., & Peffers, M. J. (2018). STRATIFYING OSTEOARTHRITIS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY PROTEOMIC ANALYSIS OF SYNOVIAL FLUID. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S171). doi:10.1016/j.joca.2018.02.372
THE ROLE OF MICRORNAS IN TENDON DYSFUNCTION
Bardell, D., Peffers, M. J., Clegg, P. D., Molloy, A. P., & Goljanek-Whysall, K. (2018). THE ROLE OF MICRORNAS IN TENDON DYSFUNCTION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165-S166). doi:10.1016/j.joca.2018.02.361
Interaction with macrophages attenuates equine fibroblast-like synoviocyte ADAMTS5 (aggrecanase-2) gene expression following inflammatory stimulation
Morgan, R. E., Clegg, P. D., Hunt, J. A., Innes, J. F., & Tew, S. R. (2018). Interaction with macrophages attenuates equine fibroblast-like synoviocyte ADAMTS5 (aggrecanase-2) gene expression following inflammatory stimulation. JOURNAL OF ORTHOPAEDIC RESEARCH, 36(08), 2178-2185. doi:10.1002/jor.23891
Biomarkers for equine joint injury and osteoarthritis
McIlwraith, C. W., Kawcak, C. E., Frisbie, D. D., Little, C. B., Clegg, P. D., Peffers, M. J., . . . Kraus, V. B. (2018). Biomarkers for equine joint injury and osteoarthritis. JOURNAL OF ORTHOPAEDIC RESEARCH, 36(3), 823-831. doi:10.1002/jor.23738
Variations during ageing in the three-dimensional anatomical arrangement of fascicles within the equine superficial digital flexor tendon
Ali, O., Comerford, E., Clegg, P., & Laird, E. G. (2018). Variations during ageing in the three-dimensional anatomical arrangement of fascicles within the equine superficial digital flexor tendon. European Cells and Materials, 35, 87-102. doi:10.22203/eCM.v035a07
Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements
Li, I. M. H., Liu, K., Neal, A., Clegg, P. D., De Val, S., & Bou-Gharios, G. (2018). Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements. SCIENTIFIC REPORTS, 8. doi:10.1038/s41598-018-19186-4
Donor age affects proteome composition of tenocyte-derived engineered tendon
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2018). Donor age affects proteome composition of tenocyte-derived engineered tendon. BMC BIOTECHNOLOGY, 18. doi:10.1186/s12896-018-0414-5
Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures
Lo Monaco, M., Merckx, G., Ratajczak, J., Gervois, P., Hilkens, P., Clegg, P., . . . Lambrichts, I. (2018). Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures. STEM CELLS INTERNATIONAL, 2018. doi:10.1155/2018/9079538
2017
Variation in the Quantity of Elastic Fibres with Degeneration in Canine Cranial Cruciate Ligaments from Labrador Retrievers
Smith, K. D., Hayashi, K., Clements, D. N., Clegg, P. D., Innes, J. F., & Comerford, E. J. (2017). Variation in the Quantity of Elastic Fibres with Degeneration in Canine Cranial Cruciate Ligaments from Labrador Retrievers. VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY, 30(6), 398-402. doi:10.3415/VCOT-17-02-0019
Aggrecan Gene Expression in Chondrocytes is Controlled by Multiple DNA Regulatory Elements.
Li, I. M. H., Liu, K., Neal, A., Clegg, P. D., De Val, S., & Bou-Gharios, G. (2017). Aggrecan Gene Expression in Chondrocytes is Controlled by Multiple DNA Regulatory Elements.. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 32 (pp. S314). Retrieved from https://www.webofscience.com/
Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
Rubio Martinez, L. M., Rioja, E., Castro Martins, M., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. Arthritis Research and Therapy. doi:10.1186/s12917-017-1244-8
Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
Rubio-Martinez, L. M., Rioja, E., Martins, M. C., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. BMC VETERINARY RESEARCH, 13. doi:10.1186/s12917-017-1244-8
Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females
Pease, L. I., Clegg, P. D., Proctor, C. J., Shanley, D. J., Cockell, S. J., & Peffers, M. J. (2017). Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. Scientific Reports, 7. doi:10.1038/s41598-017-14650-z
MicroRNA Profiling in Cartilage Ageing
Balaskas, P., Goljanek-Whysall, K., Clegg, P., Fang, Y., Cremers, A., Emans, P., . . . Peffers, M. (2017). MicroRNA Profiling in Cartilage Ageing. INTERNATIONAL JOURNAL OF GENOMICS, 2017. doi:10.1155/2017/2713725
Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.
Wardle, R., Pullman, J. A., Haldenby, S., Ressel, L., Pope, M., Clegg, P. D., . . . Peffers, M. J. (2017). Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.. Wellcome open research, 2, 60. doi:10.12688/wellcomeopenres.12176.2
Systems Approaches in Osteoarthritis: Identifying Routes to Novel Diagnostic and Therapeutic Strategies
Mueller, A. J., Peffers, M. J., Proctor, C. J., & Clegg, P. D. (2017). Systems Approaches in Osteoarthritis: Identifying Routes to Novel Diagnostic and Therapeutic Strategies. JOURNAL OF ORTHOPAEDIC RESEARCH, 35(8), 1573-1588. doi:10.1002/jor.23563
Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2017). Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis. Proteomics, 17(13-14). doi:10.1002/pmic.201700018
Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2017). Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons. Acta biomaterialia, 56, 58-64. doi:10.1016/j.actbio.2017.03.024
Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint
Davidson, R., Gardner, S., Jupp, O., Bullough, A., Butters, S., Watts, L., . . . Clark, I. (2017). Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint. Scientific Reports, 7. doi:10.1038/s41598-017-03629-5
Cross-species gene modules emerge from a systems biology approach to osteoarthritis
Mueller, A. J., Canty-Laird, E. G., Clegg, P. D., & Tew, S. R. (2017). Cross-species gene modules emerge from a systems biologyapproach to osteoarthritis. NPJ Systems Biology and Applications, 3. doi:10.1038/s41540-017-0014-3
THE EFFECT OF DONOR AGE ON ENGINEERED TENDON TISSUE DERIVED FROM TENOCYTES AND MESENCHYMAL STEM CELLS
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2017). THE EFFECT OF DONOR AGE ON ENGINEERED TENDON TISSUE DERIVED FROM TENOCYTES AND MESENCHYMAL STEM CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S88). doi:10.1016/j.joca.2017.02.137
Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis
Steinbusch, M. M. F., Fang, Y., Milner, P. I., Clegg, P. D., Young, D. A., Welting, T. J. M., & Peffers, M. J. (2017). Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis. Scientific reports, 7, 11 pages. doi:10.1038/srep43558
Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans
Soriano-Arroquia, A., Clegg, P. D., Molloy, A. P., & Goljanek-Whysall, K. (2017). Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (120). doi:10.3791/55047
Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics
Wedley, A. L., Dawson, S., Maddox, T. W., Coyne, K. P., Pinchbeck, G. L., Clegg, P., . . . Williams, N. J. (2017). Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics. VETERINARY MICROBIOLOGY, 199, 23-30. doi:10.1016/j.vetmic.2016.11.017
Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application
Lee, K. J., Clegg, P. D., Comerford, E. J., & Canty-Laird, E. G. (2017). Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application. STEM CELLS INTERNATIONAL, 2017. doi:10.1155/2017/1919845
2016
Aggrecan gene expression in chondrocytes is controlled by multiple regulatory elements
Li, I. M., Liu, K., Neal, A., Clegg, P. D., De Val, S., & Bou-Gharios, G. (2016). Aggrecan gene expression in chondrocytes is controlled by multiple regulatory elements. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A8-A9). Retrieved from https://www.webofscience.com/
Comparison of protein extraction methods in tendon for mass spectrometry analysis
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2016). Comparison of protein extraction methods in tendon for mass spectrometry analysis. In International Journal of Experimental Pathology Vol. 9 (pp. A26). Chester University.
Energy storing and positional human tendons: mechanics and changes with ageing
Patel, D., Spiesz, E. M., Thorpe, C. T., Birch, H. L., Riley, G. P., Clegg, P. D., & Screen, H. R. C. (2016). Energy storing and positional human tendons: mechanics and changes with ageing. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A3). Retrieved from https://www.webofscience.com/
Impact of ageing on TGF-Beta stimulated type I collagen production
Gumbs, J. A., Chapman, N. R., Young, D. A., Clegg, P. D., & Canty-Laird, E. G. (2016). Impact of ageing on TGF-Beta stimulated type I collagen production. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A15). Retrieved from https://www.webofscience.com/
The characterisation of canine ligament stem cells
Lee, K. J., Clegg, P. D., Comerford, E. J. V., & Canty-Laird, E. G. (2016). The characterisation of canine ligament stem cells. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A10-A11). Retrieved from https://www.webofscience.com/
A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes
Mueller, A. J., Tew, S. R., Vasieva, O., Clegg, P. D., & Canty-Laird, E. G. (2016). A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes. SCIENTIFIC REPORTS, 6, 1-14. doi:10.1038/srep33956
Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2016). Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons. Acta Biomaterialia, 42, 308-315. doi:10.1016/j.actbio.2016.06.012
A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells
Peffers, M. J., Collins, J., Loughlin, J., proctor, C., & Clegg, P. (2016). A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells. Stem Cell Research & Therapy. doi:10.1186/s13287-016-0384-2
Distribution of proteins within different compartments of tendon varies according to tendon type.
Thorpe, C. T., Karunaseelan, K. J., Ng Chieng Hin, J., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2016). Distribution of proteins within different compartments of tendon varies according to tendon type.. Journal of anatomy, 229(3), 450-458. doi:10.1111/joa.12485
Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq
Peffers, M. J., Goljanek-Whysall, K., Collins, J., Fang, Y., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq. PLOS ONE, 11(8). doi:10.1371/journal.pone.0160517
Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging
Nisolle, J. -F., Bihin, B., Kirschvink, N., Neveu, F., Clegg, P., Dugdale, A., . . . Vandeweerd, J. -M. (2016). Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging. COMPARATIVE MEDICINE, 66(4), 300-307. Retrieved from https://www.webofscience.com/
Letter to the Editor: <i>Equine</i> <i>Veterinary</i> <i>Journal</i>'<i>s</i> antimicrobial stewardship policy
Bowen, M., Marr, C. M., & Clegg, P. D. (2016). Letter to the Editor: <i>Equine</i> <i>Veterinary</i> <i>Journal</i>'<i>s</i> antimicrobial stewardship policy. EQUINE VETERINARY JOURNAL, 48(4), 532-533. doi:10.1111/evj.12589
RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes
McDermott, B., Ellis, S., Bou-Gharios, G., Clegg, P., & Tew, S. (2016). RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. Osteoarthritis and Cartilage, 24(7), 1263-1273. doi:10.1016/j.joca.2016.01.988
Ageing does not result in a decline in cell synthetic activity in an injury prone tendon
Thorpe, C. T., McDermott, B. T., Goodship, A. E., Clegg, P. D., & Birch, H. L. (2016). Ageing does not result in a decline in cell synthetic activity in an injury prone tendon. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 26(6), 684-693. doi:10.1111/sms.12500
AGE-RELATED CHANGES IN MESENCHYMAL STEM CELLS IDENTIFIED USING A MULTI-OMICS APPROACH
Peffers, M. J., Collins, J., Fang, Y., Goljanek-Whysall, K., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). AGE-RELATED CHANGES IN MESENCHYMAL STEM CELLS IDENTIFIED USING A MULTI-OMICS APPROACH. EUROPEAN CELLS & MATERIALS, 31, 136-159. doi:10.22203/eCM.v031a10
Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition
Thorpe, C. T., Peffers, M. J., Simpson, D., Halliwell, E., Screen, H. R. C., & Clegg, P. D. (2016). Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. Scientific Reports, 6. doi:10.1038/srep20455
Epidemiology of antimicrobial resistance of bacterial pathogens in equine medicine
Maddox, T. W., Clegg, P. D., Williams, N. J., & Pinchbeck, G. L. (2016). Epidemiology of antimicrobial resistance of bacterial pathogens in equine medicine. Praktische Tierarzt, 97(2), 137.
A test of the universal applicability of a commonly used principle of hoof balance
Caldwell, M. N., Allan, L. A., Pinchbeck, G., Clegg, P., Kissick, K. E., & Milner, P. (2016). A test of the universal applicability of a commonly used principle of hoof balance. Veterinary Journal, 207, 169-176. doi:10.1016/j.tvjl.2015.10.003
Characterization of Neopeptides in Equine Articular Cartilage Degradation
Peffers, M. J., Thornton, D. J., & Clegg, P. D. (2016). Characterization of Neopeptides in Equine Articular Cartilage Degradation. JOURNAL OF ORTHOPAEDIC RESEARCH, 34(1), 106-120. doi:10.1002/jor.22963
Influence of Ageing on Tendon Homeostasis
Birch, H. L., Peffers, M. J., & Clegg, P. D. (2016). Influence of Ageing on Tendon Homeostasis. METABOLIC INFLUENCES ON RISK FOR TENDON DISORDERS, 920, 247-260. doi:10.1007/978-3-319-33943-6_24
2015
The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons
Thorpe, C. T., Godinho, M. S. C., Riley, G. P., Birch, H. L., Clegg, P., & Screen, H. R. C. (2015). The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons. Journal of the Mechanical Behavior of Biomedical Materials, 52, 85-94. doi:10.1016/j.jmbbm.2015.04.009
Clinical research: developing an appropriate career structure
Mellanby, R. J., Price, J., Wooldridge, L., Jonsson, N. N., Clegg, P. D., Emes, R. D., . . . Argyle, D. J. (2015). Clinical research: developing an appropriate career structure. VETERINARY RECORD, 177(21). doi:10.1136/vr.h6169
Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance
Maddox, T. W., Clegg, P. D., Williams, N. J., & Pinchbeck, G. L. (2015). Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance. EQUINE VETERINARY JOURNAL, 47(6), 756-765. doi:10.1111/evj.12471
Antimicrobial resistance in the horse - <i>EVJ</i>'s online collection
Bowen, I. M., & Clegg, P. D. (2015). Antimicrobial resistance in the horse - <i>EVJ</i>'s online collection. EQUINE VETERINARY JOURNAL, 47(6), 745-746. doi:10.1111/evj.12495
Computed Tomography and Magnetic Resonance Anatomy of the Normal Orbit and Eye of the Horse
D'Aout, C., Nisolle, J. F., Navez, M., Perrin, R., Launois, T., Brogniez, L., . . . Vandeweerd, J. M. (2015). Computed Tomography and Magnetic Resonance Anatomy of the Normal Orbit and Eye of the Horse. ANATOMIA HISTOLOGIA EMBRYOLOGIA, 44(5), 370-377. doi:10.1111/ahe.12149
Effect of corticosteroids on articular cartilage: have animal studies said everything?
Vandeweerd, J. -M., Zhao, Y., Nisolle, J. -F., Zhang, W., Liu, Z., Clegg, P., & Gustin, P. (2015). Effect of corticosteroids on articular cartilage: have animal studies said everything?. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 29(5), 427-438. doi:10.1111/fcp.12137
PI-3K signalling is a consensus pathway in musculoskeletal de- and re-differentiation
Mueller, A. J., Tew, S. R., Canty-Laird, E. G., & Clegg, P. D. (2015). PI-3K signalling is a consensus pathway in musculoskeletal de- and re-differentiation. In Bone and Joint Journal Vol. 97-B. British Editorial Society of Bone and Joint Surgery. Retrieved from http://www.bjjprocs.boneandjoint.org.uk/content/97-B/SUPP_11/8
Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation
Thorpe, C. T., Chaudhry, S., Lei, I. I., Varone, A., Riley, G. P., Birch, H. L., . . . Screen, H. R. C. (2015). Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation. Scandinavian Journal Of Medicine & Science In Sports, 25(4), e381-e391. doi:10.1111/sms.12333
Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization
Peffers, M., McDermott, B., Clegg, P., & Riggs, C. (2015). Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization. Osteoarthritis and Cartilage, 23(7), 1204-1213. doi:10.1016/j.joca.2015.03.019
Magnetic resonance compositional imaging of articular cartilage: What can we expect in veterinary medicine?
Hontoir, F., Clegg, P., Nisolle, J. -F., Tew, S., & Vandeweerd, J. -M. (2015). Magnetic resonance compositional imaging of articular cartilage: What can we expect in veterinary medicine?. VETERINARY JOURNAL, 205(1), 11-20. doi:10.1016/j.tvjl.2015.04.035
Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions
Collins, J. A., Moots, R., Clegg, P., & Milner, P. (2015). Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions. Free Radical Biology & Medicine, 86, 57-64. doi:10.1016/j.freeradbiomed.2015.05.008
Restricted Differentiation Potential of Progenitor Cell Populations Obtained From the Equine Superficial Digital Flexor Tendon (SDFT)
Williamson, K. A., Lee, K. J., Humphreys, W. J. E., Comerford, E. J. V., Clegg, P. D., & Canty-Laird, E. G. (2015). Restricted Differentiation Potential of Progenitor Cell Populations Obtained From the Equine Superficial Digital Flexor Tendon (SDFT). JOURNAL OF ORTHOPAEDIC RESEARCH, 33(6), 849-858. doi:10.1002/jor.22891
Tendon extracellular matrix damage, degradation and inflammation in response to in-vitro overload exercise
Spiesz, E., Thorpe, C., Chaudhry, S., Riley, G., Birch, H., Clegg, P., & Screen, H. (2015). Tendon extracellular matrix damage, degradation and inflammation in response to in-vitro overload exercise. Journal of Orthopaedic Research, 33(6), 889-897. doi:10.1002/jor.22879
A topographic anatomical study of the equine epiploic foramen and comparison with laparoscopic visualisation
van Bergen, T., Doom, M., van den Broeck, W., Wiemer, P., Clegg, P. D., Cornillie, P., & Martens, A. (2015). A topographic anatomical study of the equine epiploic foramen and comparison with laparoscopic visualisation. EQUINE VETERINARY JOURNAL, 47(3), 313-318. doi:10.1111/evj.12282
Science in brief: Recent advances into understanding tendon function and injury risk
Thorpe, C. T., Spiesz, E. M., Chaudhry, S., Screen, H. R. C., & Clegg, P. D. (2015). Science in brief: Recent advances into understanding tendon function and injury risk. EQUINE VETERINARY JOURNAL, 47(2), 137-140. doi:10.1111/evj.12346
Transcriptome analysis of ageing in uninjured human Achilles tendon
Peffers, M. J., Fang, Y., Cheung, K., Wei, T. K. J., Clegg, P. D., & Birch, H. L. (2015). Transcriptome analysis of ageing in uninjured human Achilles tendon. ARTHRITIS RESEARCH & THERAPY, 17. doi:10.1186/s13075-015-0544-2
The role of polyphosphates in the sequestration of matrix metalloproteinases
McCarty, S. M., Percival, S. L., Clegg, P. D., & Cochrane, C. A. (2015). The role of polyphosphates in the sequestration of matrix metalloproteinases. INTERNATIONAL WOUND JOURNAL, 12(1), 89-99. doi:10.1111/iwj.12058
Investigation into cell specific responses during cellular interactions between equine fibroblast-like synoviocytes and canine macrophages in an inflammatory environment - development of a synovial co-culture model system
Morgan, R., Hunt, J. A., Clegg, P. D., & Tew, S. R. (2015). Investigation into cell specific responses during cellular interactions between equine fibroblast-like synoviocytes and canine macrophages in an inflammatory environment - development of a synovial co-culture model system. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 96 (pp. A28). Retrieved from https://www.webofscience.com/
Tendon Physiology and Mechanical Behavior
Thorpe, C. T., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2015). Tendon Physiology and Mechanical Behavior. In Tendon Regeneration (pp. 3-39). Elsevier. doi:10.1016/b978-0-12-801590-2.00001-6
2014
Science in brief: Report on the Havemeyer Foundation workshop on equine musculoskeletal biomarkers - current knowledge and future needs
McIlwraith, C. W., & Clegg, P. D. (2014). Science in brief: Report on the Havemeyer Foundation workshop on equine musculoskeletal biomarkers - current knowledge and future needs. EQUINE VETERINARY JOURNAL, 46(6), 651-653. doi:10.1111/evj.12339
Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes
Tew, S., McDermott, B., Fentem, R. B., Peffers, M., & Clegg, P. (2014). Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes. Arthritis and Rheumatology, 66(11), 3052-3061. doi:10.1002/art.38849
Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation
Peffers, M., Thorpe, C., Collins, J., Eong, R., Wei, T., Screen, H., & Clegg, P. (2014). Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation. The Journal of Biological Chemistry, 289(37), 25867-25878. doi:10.1074/jbc.M114.566554
54 The Stem Cell Niche In Tendon And Ligament – Investigating Alterations With Ageing And Disease
Lee, K., Williamson, K., Clegg, P., Comerford, E., & Canty-Laird, E. (2014). 54 The Stem Cell Niche In Tendon And Ligament – Investigating Alterations With Ageing And Disease. In Abstracts (pp. A35-A36). BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine. doi:10.1136/bjsports-2014-094114.54
77 Three Dimensional And Histological Study Of The Equine Superficial Digital Flexor Tendon
Ali, O., Clegg, P., Comerford, E., & Canty-Laird, E. (2014). 77 Three Dimensional And Histological Study Of The Equine Superficial Digital Flexor Tendon. In Abstracts (pp. A50-A51). BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine. doi:10.1136/bjsports-2014-094114.76
Identifying key proteoglycans in different regions of canine cranial cruciate ligament
Allaith, M. S., Tew, S., Clegg, P. D., Laird, E., Comerford, E., & Caterson, B. (2014). Identifying key proteoglycans in different regions of canine cranial cruciate ligament. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A2-A3). Retrieved from https://www.webofscience.com/
Carriage of Staphylococcus species in the veterinary visiting dog population in mainland UK: Molecular characterisation of resistance and virulence
Wedley, A. L., Dawson, S., Maddox, T. W., Coyne, K. P., Pinchbeck, G. L., Clegg, P., . . . Williams, N. J. (2014). Carriage of Staphylococcus species in the veterinary visiting dog population in mainland UK: Molecular characterisation of resistance and virulence. Veterinary Microbiology, 170(1-2), 81-88. doi:10.1016/j.vetmic.2014.01.015
Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., Eijkel, G. B., Clegg, P. D., & Heeren, R. M. A. (2014). Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage. Arthritis Research and Therapy, 16. doi:10.1186/ar4560
COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS
Peffers, M. J., McDermott, B. T., Riggs, C. M., & Clegg, P. D. (2014). COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S65-S66). doi:10.1016/j.joca.2014.02.134
LONGITUDINAL ANALYSIS OF PRIMARY HUMAN ARTICULAR CHONDROCYTE TRANSCRIPTOMIC REGULATION BY INTERLEUKIN 1β UNDER HYPEROSMOTIC CONDITIONS
Tew, S. R., McDermott, B. T., & Clegg, P. D. (2014). LONGITUDINAL ANALYSIS OF PRIMARY HUMAN ARTICULAR CHONDROCYTE TRANSCRIPTOMIC REGULATION BY INTERLEUKIN 1β UNDER HYPEROSMOTIC CONDITIONS. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S167-S168). doi:10.1016/j.joca.2014.02.312
MAPPING NOVEL PROTEIN INTERACTIONS IN THE 3'UTR OF THE MASTER CHONDROCYTE REGULATORY FACTOR SOX9
McDermott, B. T., Clegg, P. D., & Tew, S. R. (2014). MAPPING NOVEL PROTEIN INTERACTIONS IN THE 3'UTR OF THE MASTER CHONDROCYTE REGULATORY FACTOR SOX9. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S168). doi:10.1016/j.joca.2014.02.314
POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES
Peffers, M. J., Fentom, R., Tew, S. R., & Clegg, P. D. (2014). POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S62-S63). doi:10.1016/j.joca.2014.02.128
THE IDENTIFICATION AND DISTRIBUTION OF KEY PROTEOGLYCANS IN CANINE CRUCIATE LIGAMENT
Allaith, S., Clegg, P. D., Canty-Laird, E. G., Tew, S., Caterson, B., & Comerford, E. (2014). THE IDENTIFICATION AND DISTRIBUTION OF KEY PROTEOGLYCANS IN CANINE CRUCIATE LIGAMENT. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S332-S333). doi:10.1016/j.joca.2014.02.614
Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading.
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2014). Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading.. Journal of the Royal Society Interface, 11(92). doi:10.1098/rsif.2013.1058
A comparison of 3-T magnetic resonance imaging and computed tomography arthrography to identify structural cartilage defects of the fetlock joint in the horse
Hontoir, F., Nisolle, J. -F., Meurisse, H., Simon, V., Tallier, M., Vanderstricht, R., . . . Vandeweerd, J. -M. (2014). A comparison of 3-T magnetic resonance imaging and computed tomography arthrography to identify structural cartilage defects of the fetlock joint in the horse. VETERINARY JOURNAL, 199(1), 115-122. doi:10.1016/j.tvjl.2013.10.021
Advances in the understanding of tendinopathies: A report on the Second Havemeyer Workshop on equine tendon disease
Smith, R., McIlwraith, W., Schweitzer, R., Kadler, K., Cook, J., Caterson, B., . . . Nixon, A. (2014). Advances in the understanding of tendinopathies: A report on the Second Havemeyer Workshop on equine tendon disease. EQUINE VETERINARY JOURNAL, 46(1), 4-9. doi:10.1111/evj.12128
Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites
Peffers, M. J., McKnight, W., & Clegg, P. D. (2014). Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A27-A28). Retrieved from https://www.webofscience.com/
Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2014). Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons. ACTA BIOMATERIALIA, 10(7), 3217-3224. doi:10.1016/j.actbio.2014.04.008
Elastin content is high in the canine cruciate ligament and is associated with degeneration
Smith, K. D., Clegg, P. D., Innes, J. F., & Comerford, E. J. (2014). Elastin content is high in the canine cruciate ligament and is associated with degeneration. VETERINARY JOURNAL, 199(1), 169-174. doi:10.1016/j.tvjl.2013.11.002
Fatigue loading causes a reduction in the ability of tendon fascicles to recoil
Thorpe, C. T., Udeze, C. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2014). Fatigue loading causes a reduction in the ability of tendon fascicles to recoil. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A32-A33). Retrieved from https://www.webofscience.com/
Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Lumbar Spine
Nisolle, J. F., Wang, X. Q., Squelart, M., Hontoir, F., Kirschvink, N., Clegg, P., & Vandeweerd, J. M. (2014). Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Lumbar Spine. ANATOMIA HISTOLOGIA EMBRYOLOGIA, 43(3), 203-209. doi:10.1111/ahe.12063
Transcriptomic profiling of cartilage ageing.
Peffers, M. J., Liu, X., & Clegg, P. D. (2014). Transcriptomic profiling of cartilage ageing.. Genomics data, 2, 27-28. doi:10.1016/j.gdata.2014.03.001
2013
CT-guided injection technique into intervertebral discs in the ovine lumbar spine
Nisolle, J. F., Neveu, F., Hontoir, F., Clegg, P., Kirschvink, N., & Vandeweerd, J. -M. (2013). CT-guided injection technique into intervertebral discs in the ovine lumbar spine. EUROPEAN SPINE JOURNAL, 22(12), 2760-2765. doi:10.1007/s00586-013-2936-9
Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis.
Zamboulis, D. E., Senior, M., Clegg, P. D., & Milner, P. I. (2013). Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis.. Veterinary journal (London, England : 1997), 198(2), 472-478. doi:10.1016/j.tvjl.2013.08.017
Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system
Collins, J. A., Moots, R. J., Winstanley, R., Clegg, P. D., & Milner, P. I. (2013). Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system. OSTEOARTHRITIS AND CARTILAGE, 21(11), 1790-1798. doi:10.1016/j.joca.2013.06.028
Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(10), 20658-20681. doi:10.3390/ijms141020658
Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia
Zamboulis, D. E., Senior, J. M., Clegg, P. D., Gallagher, J. A., Carter, S. D., & Milner, P. I. (2013). Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia. PURINERGIC SIGNALLING, 9(3), 383-393. doi:10.1007/s11302-013-9356-5
Evaluation of cartilage, synovium and adipose tissue as cellular sources for osteochondral repair
Innes, J. F., Gordon, C., Vaughan-Thomas, A., Rhodes, N. P., & Clegg, P. D. (2013). Evaluation of cartilage, synovium and adipose tissue as cellular sources for osteochondral repair. VETERINARY JOURNAL, 197(3), 619-624. doi:10.1016/j.tvjl.2013.05.044
Horse-, training- and race-level risk factors for palmar/plantar osteochondral disease in the racing Thoroughbred
Pinchbeck, G. L., Clegg, P. D., Boyde, A., Barr, E. D., & Riggs, C. M. (2013). Horse-, training- and race-level risk factors for palmar/plantar osteochondral disease in the racing Thoroughbred. EQUINE VETERINARY JOURNAL, 45(5), 582-586. doi:10.1111/evj.12038
Pathological and clinical features associated with palmar/plantar osteochondral disease of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses
Pinchbeck, G. L., Clegg, P. D., Boyde, A., & Riggs, C. M. (2013). Pathological and clinical features associated with palmar/plantar osteochondral disease of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses. EQUINE VETERINARY JOURNAL, 45(5), 587-592. doi:10.1111/evj.12036
Transcriptomic signatures in cartilage ageing
Peffers, M. J., Liu, X., & Clegg, P. D. (2013). Transcriptomic signatures in cartilage ageing. ARTHRITIS RESEARCH & THERAPY, 15(4). doi:10.1186/ar4278
Prevalence of naturally occurring cartilage defects in the ovine knee
Vandeweerd, J. -M., Hontoir, F., Kirschvink, N., Clegg, P., Nisolle, J. -F., Antoine, N., & Gustin, P. (2013). Prevalence of naturally occurring cartilage defects in the ovine knee. OSTEOARTHRITIS AND CARTILAGE, 21(8), 1125-1131. doi:10.1016/j.joca.2013.05.006
The role of the non-collagenous matrix in tendon function
Thorpe, C. T., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2013). The role of the non-collagenous matrix in tendon function. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94(4), 248-259. doi:10.1111/iep.12027
EFFECT OF FATIGUE LOADING ON TENDON FASCICLE EXTENSION MECHANISMS
Thorpe, C. T., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2014). EFFECT OF FATIGUE LOADING ON TENDON FASCICLE EXTENSION MECHANISMS. In PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE - 2013, PT B. Retrieved from https://www.webofscience.com/
Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Stifle
Vandeweerd, J. -M., Kirschvink, N., Muylkens, B., Cintas, C., Vande Catsyne, C., Hontoir, F., . . . Nisolle, J. -F. (2013). Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Stifle. VETERINARY SURGERY, 42(5), 551-558. doi:10.1111/j.1532-950X.2013.12026.x
AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. (2013). AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S63). doi:10.1016/j.joca.2013.02.140
TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING
Peffers, M. J., Tew, S. R., & Clegg, P. D. (2013). TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S9). doi:10.1016/j.joca.2013.02.040
Antimicrobial prescribing practice in UK equine veterinary practice
Hughes, L. A., Pinchbeck, G., Callaby, R., Dawson, S., Clegg, P., & Williams, N. (2013). Antimicrobial prescribing practice in UK equine veterinary practice. EQUINE VETERINARY JOURNAL, 45(2), 141-147. doi:10.1111/j.2042-3306.2012.00602.x
Antimicrobial prescribing practice in UK equine veterinary practice
HUGHES, L. A., PINCHBECK, G., CALLABY, R., DAWSON, S., CLEGG, P., & WILLIAMS, N. (2013). Antimicrobial prescribing practice in UK equine veterinary practice. Equine Veterinary Journal, 45(2), 141-147. doi:10.1111/j.2042-3306.2012.00602.x
Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases
Fonfara, S., Hetzel, U., Tew, S. R., Cripps, P., Dukes-McEwan, J., & Clegg, P. D. (2013). Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases. AMERICAN JOURNAL OF VETERINARY RESEARCH, 74(3), 408-416. doi:10.2460/ajvr.74.3.408
Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases
Fonfara, S., Hetzel, U., Tew, S. R., Cripps, P., Dukes-McEwan, J., & Clegg, P. D. (2013). Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases. AMERICAN JOURNAL OF VETERINARY RESEARCH, 74(2), 216-223. doi:10.2460/ajvr.74.2.216
Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases.
Fonfara, S., Hetzel, U., Tew, S. R., Cripps, P., Dukes-McEwan, J., & Clegg, P. D. (2013). Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases.. American journal of veterinary research, 74(3), 408-416. doi:10.2460/ajvr.74.3.408
CAPACITY FOR SLIDING BETWEEN TENDON FASCICLES DECREASES WITH AGEING IN INJURY PRONE EQUINE TENDONS: A POSSIBLE MECHANISM FOR AGE-RELATED TENDINOPATHY?
Thorpe, C. T., Udeze, C. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2013). CAPACITY FOR SLIDING BETWEEN TENDON FASCICLES DECREASES WITH AGEING IN INJURY PRONE EQUINE TENDONS: A POSSIBLE MECHANISM FOR AGE-RELATED TENDINOPATHY?. EUROPEAN CELLS & MATERIALS, 25, 48-60. doi:10.22203/eCM.v025a04
Antimicrobial resistance changes in enteric <i>Escherichia coli</i> of horses during hospitalisation: Resistance profiling of isolates
Williams, A., Christley, R. M., McKane, S. A., Roberts, V. L. H., Clegg, P. D., & Williams, N. J. (2013). Antimicrobial resistance changes in enteric <i>Escherichia coli</i> of horses during hospitalisation: Resistance profiling of isolates. VETERINARY JOURNAL, 195(1), 121-126. doi:10.1016/j.tvjl.2012.08.001
Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia
Zamboulis, D. E., Senior, J. M., Clegg, P. D., Gallagher, J. A., Carter, S. D., & Milner, P. I. (2013). Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia. Purinergic Signalling, 9(3), 383-393. doi:10.1007/s11302-013-9356-5
Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis
Zamboulis, D. E., Senior, M., Clegg, P. D., & Milner, P. I. (2013). Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis. VETERINARY JOURNAL, 198(2), 472-478. doi:10.1016/j.tvjl.2013.08.017
Gene expression alterations in tendon-derived cells after serial passage in 2D cell culture
Mueller, A. J., Tew, S. R., Vasieva, O., Clegg, P. D., & Canty-Laird, E. G. (2013). Gene expression alterations in tendon-derived cells after serial passage in 2D cell culture. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A4-A5). Retrieved from https://www.webofscience.com/
Helical fascicles in energy storing tendons: a mechanism for efficient recoil?
Thorpe, C. T., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2013). Helical fascicles in energy storing tendons: a mechanism for efficient recoil?. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A3-A4). Retrieved from https://www.webofscience.com/
Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return
Thorpe, C. T., Klemt, C., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2013). Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return. ACTA BIOMATERIALIA, 9(8), 7948-7956. doi:10.1016/j.actbio.2013.05.004
Investigating the post-transcriptional regulatory mechanisms controlling SOX9 in chondrocytes
McDermott, B. T., Clegg, P. D., & Tew, S. R. (2013). Investigating the post-transcriptional regulatory mechanisms controlling SOX9 in chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A14-A15). Retrieved from https://www.webofscience.com/
MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. A. (2013). MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A12). Retrieved from https://www.webofscience.com/
Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system.
Collins, J. A., Moots, R. J., Winstanley, R., Clegg, P. D., & Milner, P. I. (2013). Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system.. Osteoarthritis and Cartilage, 21, 1790-1798.
Protein signatures of the human osteoarthritic cartilage secretome
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Protein signatures of the human osteoarthritic cartilage secretome. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A11-A12). Retrieved from https://www.webofscience.com/
Transcriptomic signatures in cartilage ageing
Peffers, M. J., Liu, X., & Clegg, P. D. (n.d.). Transcriptomic signatures in cartilage ageing. Arthritis Research & Therapy, 15(4). doi:10.1186/ar4278
2012
Specialization of tendon mechanical properties results from interfascicular differences
Thorpe, C. T., Udeze, C. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2012). Specialization of tendon mechanical properties results from interfascicular differences. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 9(76), 3108-3117. doi:10.1098/rsif.2012.0362
Increased blood mRNA expression of inflammatory and anti-fibrotic markers in dogs with congestive heart failure
Fonfara, S., Tew, S. R., Cripps, P., Dukes-McEwan, J., & Clegg, P. D. (2012). Increased blood mRNA expression of inflammatory and anti-fibrotic markers in dogs with congestive heart failure. RESEARCH IN VETERINARY SCIENCE, 93(2), 879-885. doi:10.1016/j.rvsc.2011.10.020
Untitled
Vandeweerd, J. -M., Clegg, P., & Buczinski, S. (2012). Untitled. JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(5), 1085-1086. doi:10.1111/j.1939-1676.2012.00974.x
A study of the anatomy and injection techniques of the ovine stifle by positive contrast arthrography, computed tomography arthrography and gross anatomical dissection
Vandeweerd, J. -M., Kirschvink, N., Muylkens, B., Depiereux, E., Clegg, P., Herteman, N., . . . Nisolle, J. -F. (2012). A study of the anatomy and injection techniques of the ovine stifle by positive contrast arthrography, computed tomography arthrography and gross anatomical dissection. VETERINARY JOURNAL, 193(2), 426-432. doi:10.1016/j.tvjl.2011.12.011
Variations in cell morphology in the canine cruciate ligament complex
Smith, K. D., Vaughan-Thomas, A., Spiller, D. G., Clegg, P. D., Innes, J. F., & Comerford, E. J. (2012). Variations in cell morphology in the canine cruciate ligament complex. VETERINARY JOURNAL, 193(2), 561-566. doi:10.1016/j.tvjl.2012.02.017
Repair or destruction: Optimising therapies for joint diseases
Clegg, P. D. (2012). Repair or destruction: Optimising therapies for joint diseases. EQUINE VETERINARY JOURNAL, 44(4), 382-383. doi:10.1111/j.2042-3306.2012.00592.x
Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus
Maddox, T. W., Clegg, P. D., Diggle, P. J., Wedley, A. L., Dawson, S., Pinchbeck, G. L., & Williams, N. J. (2012). Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus. EQUINE VETERINARY JOURNAL, 44(3), 289-296. doi:10.1111/j.2042-3306.2011.00441.x
Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses
Maddox, T. W., Pinchbeck, G. L., Clegg, P. D., Wedley, A. L., Dawson, S., & Williams, N. J. (2012). Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses. EQUINE VETERINARY JOURNAL, 44(3), 297-303. doi:10.1111/j.2042-3306.2011.00440.x
Cross-sectional survey of antimicrobial prescribing patterns in UK small animal veterinary practice
Hughes, L. A., Williams, N., Clegg, P., Callaby, R., Nuttall, T., Coyne, K., . . . Dawson, S. (2012). Cross-sectional survey of antimicrobial prescribing patterns in UK small animal veterinary practice. PREVENTIVE VETERINARY MEDICINE, 104(3-4), 309-316. doi:10.1016/j.prevetmed.2011.12.003
GLOBAL GENE EXPRESSION ANALYSIS OF DEDIFFERENTIATED CHONDROCYTES
Mueller, A. J., Laird, E. G., Tew, S. R., & Clegg, P. D. (2012). GLOBAL GENE EXPRESSION ANALYSIS OF DEDIFFERENTIATED CHONDROCYTES. In RHEUMATOLOGY Vol. 51 (pp. 49). Retrieved from https://www.webofscience.com/
Musculoskeletal disease and injury, now and in the future. Part 2: Tendon and ligament injuries
Clegg, P. D. (2012). Musculoskeletal disease and injury, now and in the future. Part 2: Tendon and ligament injuries. EQUINE VETERINARY JOURNAL, 44(3), 371-375. doi:10.1111/j.2042-3306.2012.00563.x
Systematic Review of Efficacy of Nutraceuticals to Alleviate Clinical Signs of Osteoarthritis
Vandeweerd, J. -M., Coisnon, C., Clegg, P., Cambier, C., Pierson, A., Hontoir, F., . . . Buczinski, S. (2012). Systematic Review of Efficacy of Nutraceuticals to Alleviate Clinical Signs of Osteoarthritis. JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(3), 448-456. doi:10.1111/j.1939-1676.2012.00901.x
The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells
Parker, R. A., Clegg, P. D., & Taylor, S. E. (2012). The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells. EQUINE VETERINARY JOURNAL, 44(3), 355-360. doi:10.1111/j.2042-3306.2011.00437.x
The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells
Parker, R. A., Clegg, P. D., & Taylor, S. E. (2012). The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells. Equine Veterinary Journal, 44(3), 355-360. doi:10.1111/j.2042-3306.2011.00437.x
A survey of health care and disease in geriatric horses aged 30 years or older
Ireland, J. L., McGowan, C. M., Clegg, P. D., Chandler, K. J., & Pinchbeck, G. L. (2012). A survey of health care and disease in geriatric horses aged 30 years or older. VETERINARY JOURNAL, 192(1), 57-64. doi:10.1016/j.tvjl.2011.03.021
Analysis of Risk Factors Associated with Antibiotic-Resistant <i>Escherichia coli</i>
Ahmed, M. O., Williams, N. J., Clegg, P. D., van Velkinburgh, J. C., Baptiste, K. E., & Bennett, M. (2012). Analysis of Risk Factors Associated with Antibiotic-Resistant <i>Escherichia coli</i>. MICROBIAL DRUG RESISTANCE, 18(2), 161-168. doi:10.1089/mdr.2011.0213
EFFECT OF OXYGEN TENSION AND PH ON MITOCHONDRIAL FUNCTION IN HUMAN OSTEOARTHRITIC ARTICULAR CHONDROCYTES (HOAC)
Collins, J., Moots, R., Milner, P., & Clegg, P. (2012). EFFECT OF OXYGEN TENSION AND PH ON MITOCHONDRIAL FUNCTION IN HUMAN OSTEOARTHRITIC ARTICULAR CHONDROCYTES (HOAC). In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S148-S149). doi:10.1016/j.joca.2012.02.214
PREVALENCE OF NATURALLY OCCURRING CARTILAGE DEFECTS IN THE OVINE STIFLE (KNEE)
Pierson, A., Kirschvink, N., Muylkens, B., Hontoir, F., Raes, M., Clegg, P., . . . Vandeweerd, J. -M. (2012). PREVALENCE OF NATURALLY OCCURRING CARTILAGE DEFECTS IN THE OVINE STIFLE (KNEE). In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S73-S74). doi:10.1016/j.joca.2012.02.057
PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL
Peffers, M. J., Beynon, R. J., Thornton, D., & Clegg, P. D. (2012). PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL. In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S261-S262). doi:10.1016/j.joca.2012.02.439
SUBSTANTIAL ALTERATION OF POST-TRANSCRIPTIONAL GENE CONTROL IN CHONDROCYTES FROM OSTEOARTHRITIC JOINTS
Tew, S. R., McDermott, B., Vasieva, O., & Clegg, P. D. (2012). SUBSTANTIAL ALTERATION OF POST-TRANSCRIPTIONAL GENE CONTROL IN CHONDROCYTES FROM OSTEOARTHRITIC JOINTS. OSTEOARTHRITIS AND CARTILAGE, 20, S43. doi:10.1016/j.joca.2012.02.582
THE MICRO-STRUCTURAL RESPONSE OF TENDON FASCICLES TO APPLIED MAIN IS ALTERED WITH AGEING
Thorpe, C. T., Birch, H. L., Clegg, P. D., & Screen, H. R. (2012). THE MICRO-STRUCTURAL RESPONSE OF TENDON FASCICLES TO APPLIED MAIN IS ALTERED WITH AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S246-S247). doi:10.1016/j.joca.2012.02.409
How Can Veterinarians Base Their Medical Decisions on the Best Available Scientific Evidence?
Vandeweerd, J. -M., Clegg, P., & Buczinski, S. (2012). How Can Veterinarians Base Their Medical Decisions on the Best Available Scientific Evidence?. VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 28(1), 1-+. doi:10.1016/j.cvfa.2011.12.001
Identification of risk factors for traumatic injury in the general horse population of north-west England, Midlands and north Wales
Owen, K. R., Singer, E. R., Clegg, P. D., Ireland, J. L., & Pinchbeck, G. L. (2012). Identification of risk factors for traumatic injury in the general horse population of north-west England, Midlands and north Wales. EQUINE VETERINARY JOURNAL, 44(2), 143-148. doi:10.1111/j.2042-3306.2011.00387.x
Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit
Milner, P. I., Sidwell, S., Talbot, A. M., & Clegg, P. D. (2012). Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit. Equine Veterinary Journal, 44(2), 157-162. doi:10.1111/j.2042-3306.2011.00410.x
Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit
Milner, P. I., Sidwell, S., Talbot, A. M., & Clegg, P. D. (2012). Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit. EQUINE VETERINARY JOURNAL, 44(2), 157-162. doi:10.1111/j.2042-3306.2011.00410.x
The role of endogenous and exogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing
McCarty, S. M., Cochrane, C. A., Clegg, P. D., & Percival, S. L. (2012). The role of endogenous and exogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing. WOUND REPAIR AND REGENERATION, 20(2), 125-136. doi:10.1111/j.1524-475X.2012.00763.x
Using Systematic Reviews to Critically Appraise the Scientific Information for the Bovine Veterinarian
Vandeweerd, J. -M., Clegg, P., Hougardy, V., & Buczinski, S. (2012). Using Systematic Reviews to Critically Appraise the Scientific Information for the Bovine Veterinarian. VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 28(1), 13-+. doi:10.1016/j.cvfa.2011.12.002
ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2012). ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS. In RHEUMATOLOGY Vol. 51 (pp. 98). Retrieved from https://www.webofscience.com/
Comparison of owner-reported health problems with veterinary assessment of geriatric horses in the United Kingdom
Ireland, J. L., Clegg, P. D., McGowan, C. M., McKane, S. A., Chandler, K. J., & Pinchbeck, G. L. (2012). Comparison of owner-reported health problems with veterinary assessment of geriatric horses in the United Kingdom. EQUINE VETERINARY JOURNAL, 44(1), 94-100. doi:10.1111/j.2042-3306.2011.00394.x
Disease prevalence in geriatric horses in the United Kingdom: Veterinary clinical assessment of 200 cases
Ireland, J. L., Clegg, P. D., McGowan, C. M., McKane, S. A., Chandler, K. J., & Pinchbeck, G. L. (2012). Disease prevalence in geriatric horses in the United Kingdom: Veterinary clinical assessment of 200 cases. EQUINE VETERINARY JOURNAL, 44(1), 101-106. doi:10.1111/j.2042-3306.2010.00361.x
EFFECT OF OXYGEN TENSION AND PH ON MITOCHONDRIAL FUNCTION IN HUMAN OSTEOARTHRITIC ARTICULAR CHONDROCYTES
Collins, J., Moots, R. J., Clegg, P. D., & Milner, P. I. (2012). EFFECT OF OXYGEN TENSION AND PH ON MITOCHONDRIAL FUNCTION IN HUMAN OSTEOARTHRITIC ARTICULAR CHONDROCYTES. In RHEUMATOLOGY Vol. 51 (pp. 97). Retrieved from https://www.webofscience.com/
Is evidence-based medicine so evident in veterinary research and practice? History, obstacles and perspectives
Vandeweerd, J. -M., Kirschvink, N., Clegg, P., Vandenput, S., Gustin, P., & Saegerman, C. (2012). Is evidence-based medicine so evident in veterinary research and practice? History, obstacles and perspectives. VETERINARY JOURNAL, 191(1), 28-34. doi:10.1016/j.tvjl.2011.04.013
MYOCARDIAL ICAM1 MRNA IS INCREASED IN CANINE DILATED CARDIOMYOPATHY.
Fonfara, S., Oyama, M. A., Cripps, P., Tew, S. R., & Clegg, P. D. (2012). MYOCARDIAL ICAM1 MRNA IS INCREASED IN CANINE DILATED CARDIOMYOPATHY.. JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(3), 716. Retrieved from https://www.webofscience.com/
Substantial alteration of post-transcriptional gene control in chondrocytes from osteoarthritic joints
Tew, S. R., McDermott, B., & Clegg, P. D. (2012). Substantial alteration of post-transcriptional gene control in chondrocytes from osteoarthritic joints. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 93 (pp. A22). Retrieved from https://www.webofscience.com/
The effect of treatment for obesity on articular cartilage
Macrory, L., Carter, S. D., Clegg, P. D., Vaughan-Thomas, A., & Innes, J. F. (2012). The effect of treatment for obesity on articular cartilage. Journal of Orthopaedic Research.
The role of endogenous and exogenous enzymes in chronic wounds: a focus on the implications of aberrant levels of both host and bacterial proteases in wound healing
McCarty, S. M., Cochrane, C. A., Clegg, P. D., & Percival, S. L. (2012). The role of endogenous and exogenous enzymes in chronic wounds: a focus on the implications of aberrant levels of both host and bacterial proteases in wound healing. Wound Repair Regen., 20, 125-136.
Treatment of a severe distal forelimb wound presenting with extensive laceration and distal interphalangeal joint luxation in a donkey
Brogniez, L., Launois, M. T., Perrin, R. A. R., Horn, L., Clegg, P. D., Coomer, R., . . . Vandeweerd, J. M. E. F. (2012). Treatment of a severe distal forelimb wound presenting with extensive laceration and distal interphalangeal joint luxation in a donkey. PFERDEHEILKUNDE, 28(2), 160-+. doi:10.21836/PEM20120204
Understanding Veterinary Practitioners' Decision-Making Process: Implications for Veterinary Medical Education
Vandeweerd, J. -M., Vandeweerd, S., Gustin, C., Keesemaecker, G., Cambier, C., Clegg, P., . . . Gustin, P. (2012). Understanding Veterinary Practitioners' Decision-Making Process: Implications for Veterinary Medical Education. JOURNAL OF VETERINARY MEDICAL EDUCATION, 39(2), 142-151. doi:10.3138/jvme.0911.098R1
2011
HBLB's advances in equine veterinary science and practice: Musculoskeletal disease and injury, now and in the future. Part 1: Fractures and fatalities
Clegg, P. D. (2011). HBLB's advances in equine veterinary science and practice: Musculoskeletal disease and injury, now and in the future. Part 1: Fractures and fatalities. Equine Veterinary Journal, 43(6), 643-649. doi:10.1111/j.2042-3306.2011.00457.x
Musculoskeletal disease and injury, now and in the future. Part 1: Fractures and fatalities
Clegg, P. D. (2011). Musculoskeletal disease and injury, now and in the future. Part 1: Fractures and fatalities. EQUINE VETERINARY JOURNAL, 43(6), 643-649. doi:10.1111/j.2042-3306.2011.00457.x
Owners' perceptions of quality of life in geriatric horses: a cross-sectional study
Ireland, J. L., Clegg, P. D., McGowan, C. M., Duncan, J. S., McCall, S., Platt, L., & Pinchbeck, G. L. (2011). Owners' perceptions of quality of life in geriatric horses: a cross-sectional study. ANIMAL WELFARE, 20(4), 483-495. Retrieved from https://www.webofscience.com/
Factors associated with mortality of geriatric horses in the United Kingdom
Ireland, J. L., Clegg, P. D., McGowan, C. M., Platt, L., & Pinchbeck, G. L. (2011). Factors associated with mortality of geriatric horses in the United Kingdom. PREVENTIVE VETERINARY MEDICINE, 101(3-4), 204-218. doi:10.1016/j.prevetmed.2011.06.002
Leptin Expression in Dogs with Cardiac Disease and Congestive Heart Failure
Fonfara, S., Hetzel, U., Tew, S. R., Dukes-Mcewan, J., Cripps, P., & Clegg, P. D. (2011). Leptin Expression in Dogs with Cardiac Disease and Congestive Heart Failure. JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(5), 1017-1024. doi:10.1111/j.1939-1676.2011.00782.x
Collection and Propagation Methods for Mesenchymal Stromal Cells
Taylor, S. E., & Clegg, P. D. (2011). Collection and Propagation Methods for Mesenchymal Stromal Cells. VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 27(2), 263-+. doi:10.1016/j.cveq.2011.05.003
Evidence-Based Medicine and Stem Cell Therapy: How Do We Know Such Technologies are Safe and Efficacious?
Clegg, P. D., & Pinchbeck, G. L. (2011). Evidence-Based Medicine and Stem Cell Therapy: How Do We Know Such Technologies are Safe and Efficacious?. VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 27(2), 373-+. doi:10.1016/j.cveq.2011.04.002
Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions
Tew, S. R., Vasieva, O., Peffers, M. J., & Clegg, P. D. (2011). Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions. OSTEOARTHRITIS AND CARTILAGE, 19(8), 1036-1046. doi:10.1016/j.joca.2011.04.015
Stem Cell-based Therapies for Bone Repair
Milner, P. I., Clegg, P. D., & Stewart, M. C. (2011). Stem Cell-based Therapies for Bone Repair. VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 27(2), 299-+. doi:10.1016/j.cveq.2011.05.002
Analysis of Post Transcriptional Regulation of SOX9 mRNA During <i>In Vitro</i> Chondrogenesis
Tew, S. R., & Clegg, P. D. (2011). Analysis of Post Transcriptional Regulation of SOX9 mRNA During <i>In Vitro</i> Chondrogenesis. TISSUE ENGINEERING PART A, 17(13-14), 1801-1807. doi:10.1089/ten.tea.2010.0579
Longitudinal study of antimicrobial-resistant commensal <i>Escherichia coli</i> in the faeces of horses in an equine hospital
Maddox, T. W., Williams, N. J., Clegg, P. D., O'Donnell, A. J., Dawson, S., & Pinchbeck, G. L. (2011). Longitudinal study of antimicrobial-resistant commensal <i>Escherichia coli</i> in the faeces of horses in an equine hospital. PREVENTIVE VETERINARY MEDICINE, 100(2), 134-145. doi:10.1016/j.prevetmed.2011.02.006
The organisation of elastin and fibrillins 1 and 2 in the cruciate ligament complex
Smith, K. D., Vaughan-Thomas, A., Spiller, D. G., Innes, J. F., Clegg, P. D., & Comerford, E. J. (2011). The organisation of elastin and fibrillins 1 and 2 in the cruciate ligament complex. JOURNAL OF ANATOMY, 218(6), 600-607. doi:10.1111/j.1469-7580.2011.01374.x
The use of computed tomography to assist orthopaedic surgery in 86 horses (2002-2010)
Perrin, R. A. R., Launois, M. T., Brogniez, L., Clegg, P. D., Coomer, R. P. C., Desbrosse, F. G., & Vandeweerd, J. M. E. F. (2011). The use of computed tomography to assist orthopaedic surgery in 86 horses (2002-2010). EQUINE VETERINARY EDUCATION, 23(6), 306-313. doi:10.1111/j.2042-3292.2010.00159.x
CARTILAGE DAMAGE INVOLVING EXTRUSION OF MINERALISABLE MATRIX FROM THE ARTICULAR CALCIFIED CARTILAGE AND SUBCHONDRAL BONE
Boyde, A., Riggs, C. M., Bushby, A. J., McDermott, B., Pinchbeck, G. L., & Clegg, P. D. (2011). CARTILAGE DAMAGE INVOLVING EXTRUSION OF MINERALISABLE MATRIX FROM THE ARTICULAR CALCIFIED CARTILAGE AND SUBCHONDRAL BONE. EUROPEAN CELLS & MATERIALS, 21, 470-478. doi:10.22203/eCM.v021a35
Muc5b Is the Major Polymeric Mucin in Mucus from Thoroughbred Horses With and Without Airway Mucus Accumulation
Rousseau, K., Cardwell, J. M., Humphrey, E., Newton, R., Knight, D., Clegg, P., & Thornton, D. J. (2011). Muc5b Is the Major Polymeric Mucin in Mucus from Thoroughbred Horses With and Without Airway Mucus Accumulation. PLOS ONE, 6(5). doi:10.1371/journal.pone.0019678
Microbiology of equine wounds and evidence of bacterial biofilms
Westgate, S. J., Percival, S. L., Knottenbelt, D. C., Clegg, P. D., & Cochrane, C. A. (2011). Microbiology of equine wounds and evidence of bacterial biofilms. VETERINARY MICROBIOLOGY, 150(1-2), 152-159. doi:10.1016/j.vetmic.2011.01.003
Microbiology of equine wounds and evidence of bacterial biofilms
Westgate, S. J., Percival, S. L., Knottenbelt, D. C., Clegg, P. D., & Cochrane, C. A. (2011). Microbiology of equine wounds and evidence of bacterial biofilms. Veterinary Microbiology, 150(1-2), 152-159. doi:10.1016/j.vetmic.2011.01.003
A cross-sectional study of geriatric horses in the United Kingdom. Part 1: Demographics and management practices
Ireland, J. L., Clegg, P. D., McGowan, C. M., McKane, S. A., & Pinchbeck, G. L. (2011). A cross-sectional study of geriatric horses in the United Kingdom. Part 1: Demographics and management practices. EQUINE VETERINARY JOURNAL, 43(1), 30-36. doi:10.1111/j.2042-3306.2010.00145.x
A cross-sectional study of geriatric horses in the United Kingdom. Part 2: Health care and disease
Ireland, J. L., Clegg, P. D., McGowan, C. M., McKane, S. A., & Pinchbeck, G. L. (2011). A cross-sectional study of geriatric horses in the United Kingdom. Part 2: Health care and disease. EQUINE VETERINARY JOURNAL, 43(1), 37-44. doi:10.1111/j.2042-3306.2010.00142.x
Absolute quantification of the equine early osteoarthritis secretome using QconCAT
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Absolute quantification of the equine early osteoarthritis secretome using QconCAT. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A20-A21). Retrieved from https://www.webofscience.com/
Are changes in the cartilage and synovial membrane in a traumatic equine osteochondral disease similar to those seen in chronic human osteoarthritis?
McDermott, B. T., Riggs, C. M., Boyde, A., Pinchbeck, G. L., Barr, E. D., & Clegg, P. D. (2011). Are changes in the cartilage and synovial membrane in a traumatic equine osteochondral disease similar to those seen in chronic human osteoarthritis?. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A28). Retrieved from https://www.webofscience.com/
Development of a luciferase-based reporter system to analyse post-transcriptional gene regulation in osteoarthritis
McDermott, B. T., Tew, S. R., & Clegg, P. D. (2011). Development of a luciferase-based reporter system to analyse post-transcriptional gene regulation in osteoarthritis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A31-A32). Retrieved from https://www.webofscience.com/
Disease prevalence in geriatric horses in the United Kingdom: Veterinary clinical assessment of 200 cases
Ireland, J. L., Clegg, P. D., McGowan, C. M., McKane, S. A., Chandler, K. J., & Pinchbeck, G. L. (2011). Disease prevalence in geriatric horses in the United Kingdom: Veterinary clinical assessment of 200 cases. Equine Veterinary Journal. doi:10.1111/j.2042-3306.2010.00361
Effect of oxygen tension and pH on cell viability and GAG release in human osteoarthritic articular chondrocytes
Collins, J. A., Winstanley, R., Moots, R. J., Clegg, P. D., & Milner, P. I. (2011). Effect of oxygen tension and pH on cell viability and GAG release in human osteoarthritic articular chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A19-A20). Retrieved from https://www.webofscience.com/
Evidence for a novel destructive mechanism in hyaline articular cartilage (HAC) involving extrusion of mineralised matrix from the articular calcified cartilage (ACC) and subchondral bone
Boyde, A., Riggs, C. M., Pinchbeck, G. L., & Clegg, P. D. (2011). Evidence for a novel destructive mechanism in hyaline articular cartilage (HAC) involving extrusion of mineralised matrix from the articular calcified cartilage (ACC) and subchondral bone. JOURNAL OF ANATOMY, 218(3), 351-352. Retrieved from https://www.webofscience.com/
Extrusion of mineralisable matrix via articular calcified cartilage and subchondral bone forming hard outcrops in hyaline articular cartilage: a novel mechanism in cartilage loss
Boyde, A., Riggs, C. M., Bushby, A. J., Pinchbeck, G. L., & Clegg, P. D. (2011). Extrusion of mineralisable matrix via articular calcified cartilage and subchondral bone forming hard outcrops in hyaline articular cartilage: a novel mechanism in cartilage loss. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A17). Retrieved from https://www.webofscience.com/
Is it evident that veterinary surgeons should adopt the Evidence-Based Medicine (EBM) approach
Vandeweerd, J. M., Kirschvink, N., Clegg, P., Vandenput, S., Gustin, P., & Saegerman, C. (2011). Is it evident that veterinary surgeons should adopt the Evidence-Based Medicine (EBM) approach. The Veterinary Journal.
LEPTIN EXPRESSION IN BLOOD AND MYOCARDIAL SAMPLES OF DOGS WITH CARDIAC DISEASE
Fonfara, S., Hetzel, U., Tew, S. R., Dukes-McEwan, J., & Clegg, P. D. (2011). LEPTIN EXPRESSION IN BLOOD AND MYOCARDIAL SAMPLES OF DOGS WITH CARDIAC DISEASE. JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(3), 649-650. Retrieved from https://www.webofscience.com/
Longitudinal Study of Antimicrobial Resistant Commensal Escherichia Coli in the Faeces of Horses in an Equine Hospital
Maddox, T., Williams, N., Clegg, P., O'Donnell, A., Dawson, S., & Pinchbeck, G. (2011). Longitudinal Study of Antimicrobial Resistant Commensal Escherichia Coli in the Faeces of Horses in an Equine Hospital. Veterinary Preventive Medicine, 100(2 (SI), 134-145.
Protein profiling of pathological cartilage
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Protein profiling of pathological cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A18-A19). Retrieved from https://www.webofscience.com/
Regulation of SOX9 mRNA decay correlates with overall SOX9 levels in human articular chondrocytes: evidence for the involvement of the RNA binding protein tristetraprolin
Tew, S. R., & Clegg, P. D. (2011). Regulation of SOX9 mRNA decay correlates with overall SOX9 levels in human articular chondrocytes: evidence for the involvement of the RNA binding protein tristetraprolin. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A31). Retrieved from https://www.webofscience.com/
Synthesis <i>vs</i>. degradation of Prostaglandin E<sub>2</sub>: a comparison of gene expression in normal and injured equine tendon
Dakin, S. G., Dudhia, J., Young, N. J., Clegg, P. D., & Smith, R. K. W. (2011). Synthesis <i>vs</i>. degradation of Prostaglandin E<sub>2</sub>: a comparison of gene expression in normal and injured equine tendon. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A19). Retrieved from https://www.webofscience.com/
Tendon material properties cannot be predicted by the material properties of the tendon fascicles
Thorpe, C. T., Udeze, C. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2011). Tendon material properties cannot be predicted by the material properties of the tendon fascicles. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A10). Retrieved from https://www.webofscience.com/
2010
Computed Tomography to Identify Preoperative Guidelines for Internal Fixation of the Distal Sesamoid Bone in Horses: An In Vitro Study
Perrin, R., Launois, T., Brogniez, L., Desbrosse, F. G., Coomer, R. P., Clegg, P. D., . . . Vandeweerd, J. -M. E. (2010). Computed Tomography to Identify Preoperative Guidelines for Internal Fixation of the Distal Sesamoid Bone in Horses: An In Vitro Study. VETERINARY SURGERY, 39(8), 1030-1036. doi:10.1111/j.1532-950X.2010.00749.x
Post-transcriptional gene regulation in chondrocytes
Tew, S. R., & Clegg, P. D. (2010). Post-transcriptional gene regulation in chondrocytes. BIOCHEMICAL SOCIETY TRANSACTIONS, 38, 1627-1631. doi:10.1042/BST0381627
Proposed Definitions and Criteria for Reporting Time Frame, Outcome, and Complications For Clinical Orthopedic Studies in Veterinary Medicine
Cook, J. L., Evans, R., Conzemius, M. G., Lascelles, B. D. X., McIlwraith, C. W., Pozzi, A., . . . Stewart, A. (2010). Proposed Definitions and Criteria for Reporting Time Frame, Outcome, and Complications For Clinical Orthopedic Studies in Veterinary Medicine. VETERINARY SURGERY, 39(8), 905-908. doi:10.1111/j.1532-950X.2010.00763.x
Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading
Peffers, M. J., Milner, P. I., Tew, S. R., & Clegg, P. D. (2010). Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading. OSTEOARTHRITIS AND CARTILAGE, 18(11), 1502-1508. doi:10.1016/j.joca.2010.08.011
Haemoperitoneum in horses: a retrospective review of 54 cases
Conwell, R. C., Hillyer, M. H., Mair, T. S., Pirie, R. S., & Clegg, P. D. (2010). Haemoperitoneum in horses: a retrospective review of 54 cases. VETERINARY RECORD, 167(14), 514-518. doi:10.1136/vr.c4569
CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED
Peffers, M. J., Clegg, P. D., Tew, S., & Milne, P. I. (2010). CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED. In OSTEOARTHRITIS AND CARTILAGE Vol. 18 (pp. S125). doi:10.1016/S1063-4584(10)60306-8
IDENTIFICATION OF POST-TRANSCRIPTIONALLY REGULATED GENES FOLLOWING EXPOSURE OF HUMAN ARTICULAR CHONDROCYTES TO HYPEROSMOTIC CONDITIONS
Tew, S. R., & Clegg, P. D. (2010). IDENTIFICATION OF POST-TRANSCRIPTIONALLY REGULATED GENES FOLLOWING EXPOSURE OF HUMAN ARTICULAR CHONDROCYTES TO HYPEROSMOTIC CONDITIONS. In OSTEOARTHRITIS AND CARTILAGE Vol. 18 (pp. S99). doi:10.1016/S1063-4584(10)60237-3
Investigating the efficacy of articular medications in the horse: The science behind clinical practices
Clegg, P. D. (2010). Investigating the efficacy of articular medications in the horse: The science behind clinical practices. EQUINE VETERINARY JOURNAL, 42(6), 484-486. doi:10.1111/j.2042-3306.2010.00210.x
Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis
Garvican, E. R., Vaughan-Thomas, A., Innes, J. F., & Clegg, P. D. (2010). Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis. VETERINARY JOURNAL, 185(1), 36-42. doi:10.1016/j.tvjl.2010.04.011
Biomarkers of cartilage turnover. Part 2: Non-collagenous markers
Garvican, E. R., Vaughan-Thomas, A., Clegg, P. D., & Innes, J. F. (2010). Biomarkers of cartilage turnover. Part 2: Non-collagenous markers. VETERINARY JOURNAL, 185(1), 43-49. doi:10.1016/j.tvjl.2010.04.012
Chronic Equine Wounds: What Is the Role of Infection and Biofilms?
Westgate, S. J., Percival, S. L., Knottenbelt, D. C., Clegg, P. D., & Cochrane, C. A. (2010). Chronic Equine Wounds: What Is the Role of Infection and Biofilms?. WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE, 22(6), 138-145. Retrieved from https://www.webofscience.com/
Comparative rheumatology: what can be learnt from naturally occurring musculoskeletal disorders in domestic animals?
Innes, J. F., & Clegg, P. (2010). Comparative rheumatology: what can be learnt from naturally occurring musculoskeletal disorders in domestic animals?. RHEUMATOLOGY, 49(6), 1030-1039. doi:10.1093/rheumatology/kep465
Chronic equine wounds: what is the role of infection and biofilms?.
Westgate, S. J., Percival, S. L., Knottenbelt, D. C., Clegg, P. D., & Cochrane, C. A. (2010). Chronic equine wounds: what is the role of infection and biofilms?.. Wounds : a compendium of clinical research and practice, 22(6), 138-145.
Aspartic Acid Racemization and Collagen Degradation Markers Reveal an Accumulation of Damage in Tendon Collagen That Is Enhanced with Aging
Thorpe, C. T., Streeter, I., Pinchbeck, G. L., Goodship, A. E., Clegg, P. D., & Birch, H. L. (2010). Aspartic Acid Racemization and Collagen Degradation Markers Reveal an Accumulation of Damage in Tendon Collagen That Is Enhanced with Aging. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(21), 15674-15681. doi:10.1074/jbc.M109.077503
Antimicrobial resistance in equine faecal Escherichia coli isolates from North West England
Ahmed, M. O., Clegg, P. D., Williams, N. J., Baptiste, K. E., & Bennett, M. (2010). Antimicrobial resistance in equine faecal Escherichia coli isolates from North West England. ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 9. doi:10.1186/1476-0711-9-12
The organization of microfibrils and elastin fibres within the canine cruciate ligament complex
Smith, K. D., Vaughan-Thomas, A., Clegg, P. D., Spiller, D., Innes, J. F., & Comerford, E. J. (2010). The organization of microfibrils and elastin fibres within the canine cruciate ligament complex. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 91(2), A43. Retrieved from https://www.webofscience.com/
A review of tendon injury: Why is the equine superficial digital flexor tendon most at risk?
Thorpe, C. T., Clegg, P. D., & Birch, H. L. (2010). A review of tendon injury: Why is the equine superficial digital flexor tendon most at risk?. EQUINE VETERINARY JOURNAL, 42(2), 174-180. doi:10.2746/042516409X480395
A review of tendon injury: Why is the equine superficial digital flexor tendon most at risk?
THORPE, C. T., CLEGG, P. D., & BIRCH, H. L. (2010). A review of tendon injury: Why is the equine superficial digital flexor tendon most at risk?. Equine Veterinary Journal, 42(2), 174-180. doi:10.2746/042516409x480395
MMP-Mediated Collagen Breakdown Induced by Activated Protein C in Equine Cartilage Is Reduced by Corticosteroids
Garvican, E. R., Vaughan-Thomas, A., Redmond, C., Gabriel, N., & Clegg, P. D. (2010). MMP-Mediated Collagen Breakdown Induced by Activated Protein C in Equine Cartilage Is Reduced by Corticosteroids. JOURNAL OF ORTHOPAEDIC RESEARCH, 28(3), 370-378. doi:10.1002/jor.21001
A review of the characteristics and treatment of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) in the horse and a case series of MRSA infection in four horses
Maddox, T. W., Scantlebury, C. E., Clegg, P. D., Dawson, S., Pinchbeck, G. L., & Williams, N. J. (2010). A review of the characteristics and treatment of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) in the horse and a case series of MRSA infection in four horses. EQUINE VETERINARY EDUCATION, 22(2), 91-102. doi:10.1111/j.2042-3292.2009.00026.x
A review of the characteristics and treatment of methicillin‐resistant <i>Staphylococcus aureus</i> (MRSA) in the horse and a case series of MRSA infection in four horses
Maddox, T. W., Scantlebury, C. E., Clegg, P. D., Dawson, S., Pinchbeck, G. L., & Williams, N. J. (2010). A review of the characteristics and treatment of methicillin‐resistant <i>Staphylococcus aureus</i> (MRSA) in the horse and a case series of MRSA infection in four horses. Equine Veterinary Education, 22(2), 91-102. doi:10.1111/j.2042-3292.2009.00026.x
Cytokine and matrix metalloproteinase expression in blood samples of dogs with congestive heart failure.
Fonfara, S., Tew, S., Clegg, P., & Dukes-McEwan, J. (2010). Cytokine and matrix metalloproteinase expression in blood samples of dogs with congestive heart failure.. In ACVIM (pp. 1). Anaheim: ACVIM.
Cytokine and matrix metalloproteinase expression in myocardium of dogs with cardiac disease.
Fonfara, S., Tew, S., Hetzel, U., Clegg, P., & Dukes-McEwan, J. (2010). Cytokine and matrix metalloproteinase expression in myocardium of dogs with cardiac disease.. In ACVIM (pp. 153). Anaheim: ACVIM.
Cytokine and matrix metalloproteinase expression in myocardium of dogs with cardiac disease.
Fonfara, S., Tew, S., Hetzel, U., Clegg, P., & Dukes-McEwan, J. (2010). Cytokine and matrix metalloproteinase expression in myocardium of dogs with cardiac disease.. Proceedings of the American College of Veterinary Internal Medicine Forum., Jun 20, 153.
Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy
Brew, C. J., Clegg, P. D., Boot-Handford, R. P., Andrew, J. G., & Hardingham, T. (2010). Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy. ANNALS OF THE RHEUMATIC DISEASES, 69(1), 234-240. doi:10.1136/ard.2008.097139
Matrix genes show a different pattern of expression in functionally distinct equine tendons
Thorpe, C. T., Clegg, P. D., Goodship, A. E., & Birch, H. L. (2010). Matrix genes show a different pattern of expression in functionally distinct equine tendons. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A25). Retrieved from https://www.webofscience.com/
The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes
Peffers, M. J., Tew, S. R., Milner, P. I., & Clegg, P. D. (2010). The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A38). Retrieved from https://www.webofscience.com/
2009
Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems
Taylor, S. E., Vaughan-Thomas, A., Clements, D. N., Pinchbeck, G., Macrory, L. C., Smith, R. K. W., & Clegg, P. D. (2009). Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems. BMC Musculoskeletal Disorders, 10(1). doi:10.1186/1471-2474-10-27
Evaluation of a vessel-sealing device to assist eye enucleation and exenteration in the horse
Launois, M. T., Vandeweerd, J. M. E. F., Perrin, R. A. R., Brogniez, L., Gabriel, A., Coomer, R., . . . Desbrosse, F. G. (2009). Evaluation of a vessel-sealing device to assist eye enucleation and exenteration in the horse. EQUINE VETERINARY EDUCATION, 21(11), 596-601. doi:10.2746/095777309X477834
Clegg, P. D. (2009). . The Veterinary Journal, 182(2), 362-363. doi:10.1016/j.tvjl.2009.05.015
Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes
Tew, S. R., Peffers, M. J., McKay, T. R., Lowe, E. T., Khan, W. S., Hardingham, T. E., & Clegg, P. D. (2009). Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 297(4), C898-C906. doi:10.1152/ajpcell.00571.2008
Tendon-derived cells differentially modulate proliferation of mesenchymal progenitor cells from different sources
Abdulrazzak, H., Dudhia, J., Clegg, P. D., & Smith, R. K. W. (2009). Tendon-derived cells differentially modulate proliferation of mesenchymal progenitor cells from different sources. In European Cells and Materials Vol. 18 (pp. 36).
An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine <i>in vitro</i> model
Macrory, L., Vaughan-Thomas, A., Clegg, P. D., & Innes, J. F. (2009). An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine <i>in vitro</i> model. BMC VETERINARY RESEARCH, 5. doi:10.1186/1746-6148-5-25
Validation of a client-based clinical metrology instrument for the evaluation of canine elbow osteoarthritis
Hercock, C. A., Pinchbeck, G., Giejda, A., Clegg, P. D., & Innes, J. F. (2009). Validation of a client-based clinical metrology instrument for the evaluation of canine elbow osteoarthritis. JOURNAL OF SMALL ANIMAL PRACTICE, 50(6), 266-271. doi:10.1111/j.1748-5827.2009.00765.x
Antimicrobial use in companion animal and equine practice
Hughes, L., Dawson, S., Clegg, P., Pinchbeck, G., Nuttall, T., Clough, H., & Williams, N. J. (2009). Antimicrobial use in companion animal and equine practice. VETERINARY RECORD, 164(19), 604. doi:10.1136/vr.164.19.604
<i>Post mortem</i> evaluation of palmar osteochondral disease (traumatic osteochondrosis) of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses
Barr, E. D., Pinchbeck, G. L., Clegg, P. D., Boyde, A., & Riggs, C. M. (2009). <i>Post mortem</i> evaluation of palmar osteochondral disease (traumatic osteochondrosis) of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses. EQUINE VETERINARY JOURNAL, 41(4), 366-371. doi:10.2746/042516409X368372
Effects of Hypoxia on Glucose Transport in Primary Equine Chondrocytes <i>In Vitro</i> and Evidence of Reduced GLUT1 Gene Expression in Pathologic Cartilage <i>In Vivo</i>
Peansukmanee, S., Vaughan-Thomas, A., Carter, S. D., Clegg, P. D., Taylor, S., Redmond, C., & Mobasheri, A. (2009). Effects of Hypoxia on Glucose Transport in Primary Equine Chondrocytes <i>In Vitro</i> and Evidence of Reduced GLUT1 Gene Expression in Pathologic Cartilage <i>In Vivo</i>. JOURNAL OF ORTHOPAEDIC RESEARCH, 27(4), 529-535. doi:10.1002/jor.20772
Use of Computed Tomography in Standing Position to Identify Guidelines for Screw Insertion in the Distal Phalanx of Horses: An Ex Vivo Study
Vandeweerd, J. -M. E., Perrin, R., Launois, T., Brogniez, L., Clegg, P. D., & Desbrosse, F. G. (2009). Use of Computed Tomography in Standing Position to Identify Guidelines for Screw Insertion in the Distal Phalanx of Horses: An Ex Vivo Study. VETERINARY SURGERY, 38(3), 373-379. doi:10.1111/j.1532-950X.2009.00502.x
Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems
Taylor, S. E., Vaughan-Thomas, A., Clements, D. N., Pinchbeck, G., Macrory, L. C., Smith, R. K. W., & Clegg, P. D. (2009). Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems. BMC MUSCULOSKELETAL DISORDERS, 10. doi:10.1186/1471-2474-10-27
Use of computed tomography to diagnose new bone formation associated with desmitis of the proximal aspect of the suspensory ligament in third metacarpal or third metatarsal bones of three horses
Launois, M. T., Vandeweerd, J. -M. E. F., Perrin, R. A. R., Brogniez, L., Desbrosse, F. G., & Clegg, P. D. (2009). Use of computed tomography to diagnose new bone formation associated with desmitis of the proximal aspect of the suspensory ligament in third metacarpal or third metatarsal bones of three horses. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 234(4), 514-518. doi:10.2460/javma.234.4.514
The influence of donor and hypoxic conditions on the assembly of cartilage matrix by osteoarthritic human articular chondrocytes on Hyalograft matrices
Katopodi, T., Tew, S. R., Clegg, P. D., & Hardingham, T. E. (2009). The influence of donor and hypoxic conditions on the assembly of cartilage matrix by osteoarthritic human articular chondrocytes on Hyalograft matrices. BIOMATERIALS, 30(4), 535-540. doi:10.1016/j.biomaterials.2008.09.064
Chondrocytes harvested from equine osteochondritis dissecans cartilage are able to undergo limited <i>in-vitro</i> chondrogenesis despite having perturbations of cell phenotype <i>in-vivo</i>
Garvican, E. R., Vaughan-Thomas, A., Redmond, C., & Clegg, P. D. (2009). Chondrocytes harvested from equine osteochondritis dissecans cartilage are able to undergo limited <i>in-vitro</i> chondrogenesis despite having perturbations of cell phenotype <i>in-vivo</i>. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 90(1), A52-A53. Retrieved from https://www.webofscience.com/
Evaluation of a vessel sealing device to assist eye enucleation and exenteration in the horse.
Launois, M. T., Vanderweerd, J. M., Perrin, R. A., Brogniez, L., Gabriel, A., Coomer, R., . . . Desbrosse, F. G. (2009). Evaluation of a vessel sealing device to assist eye enucleation and exenteration in the horse.. Equine Veterinary Education ,, 21, 603-609.
Markers of osteoarthritis altered in the subchondral bone are also altered in the cartilage of horses with palmar osteochondral disease
Barr, E. D., Riggs, C. M., & Clegg, P. D. (2009). Markers of osteoarthritis altered in the subchondral bone are also altered in the cartilage of horses with palmar osteochondral disease. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 90(1), A56. Retrieved from https://www.webofscience.com/
Matrix ageing in functionally distinct equine tendons
Thorpe, C. T., Goodship, A. E., Clegg, P. D., & Birch, H. L. (2009). Matrix ageing in functionally distinct equine tendons. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 90 (pp. A58-A59). Retrieved from https://www.webofscience.com/
The potential for matrix synthesis and degradation in functionally distinct equine tendons
Thorpe, C. T., Goodship, A. E., Clegg, P. D., & Birch, H. L. (2009). The potential for matrix synthesis and degradation in functionally distinct equine tendons. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 90(2), A132. Retrieved from https://www.webofscience.com/
2008
High-intensity exercise induces structural, compositional and metabolic changes in cuboidal bones - findings from an equine athlete model
Tidswell, H. K., Innes, J. F., Avery, N. C., Clegg, P. D., Barr, A. R. S., Vaughan-Thomas, A., . . . Tarlton, J. F. (2008). High-intensity exercise induces structural, compositional and metabolic changes in cuboidal bones - findings from an equine athlete model. BONE, 43(4), 724-733. doi:10.1016/j.bone.2008.06.003
MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis
Garvican, E. R., Vaughan-Thomas, A., Redmond, C., & Clegg, P. D. (2008). MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis. CONNECTIVE TISSUE RESEARCH, 49(2), 62-67. doi:10.1080/03008200801913338
Chondrocytes harvested from osteochondritis dissecans cartilage are able to undergo limited in vitro chondrogenesis despite having perturbations of cell phenotype in vivo
Garvican, E. R., Vaughan-Thomas, A., Redmond, C., & Clegg, P. D. (2008). Chondrocytes harvested from osteochondritis dissecans cartilage are able to undergo limited in vitro chondrogenesis despite having perturbations of cell phenotype in vivo. JOURNAL OF ORTHOPAEDIC RESEARCH, 26(8), 1133-1140. doi:10.1002/jor.20602
Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva
Rousseau, K., Kirkham, S., Johnson, L., Fitzpatrick, B., Howard, M., Adams, E. J., . . . Thornton, D. J. (2008). Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva. BIOCHEMICAL JOURNAL, 413, 545-552. doi:10.1042/BJ20080260
A technique for computed tomography (CT) of the foot in the standing horse
Desbrosse, F. G., Vandeweerd, J. -M. E. F., Perrin, R. A. R., Clegg, P. D., Launois, M. T., Brogniez, L., & Gehin, S. P. (2008). A technique for computed tomography (CT) of the foot in the standing horse. EQUINE VETERINARY EDUCATION, 20(2), 93-98. doi:10.2746/095777308X272085
Antimicrobial resistance in dogs and horses
Maddox, T. W., Wedley, A. L., Dawson, S., Clegg, P., Pinchbeck, G. L., Nuttall, T., & Williams, N. J. (2008). Antimicrobial resistance in dogs and horses. VETERINARY RECORD, 162(2), 63. doi:10.1136/vr.162.2.63-a
Activated Protein C synergises with IL-1 to drive MMP-mediated collagen breakdown in an <i>in-vitro</i> model of equine cartilage degradation.
Garvican, E. R., Vaughan-Thomas, A., & Clegg, P. D. (2008). Activated Protein C synergises with IL-1 to drive MMP-mediated collagen breakdown in an <i>in-vitro</i> model of equine cartilage degradation.. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 89 (pp. A14-A15). Retrieved from https://www.webofscience.com/
Can exogenous multipotent mesenchymal stromal cells (MSCs) improve tendon repair?
O'Brien, E., McGrouther, D. A., Clegg, P. D., Hardingham, T. E., & Kielty, C. M. (2008). Can exogenous multipotent mesenchymal stromal cells (MSCs) improve tendon repair?. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 89 (pp. A5-A6). Retrieved from https://www.webofscience.com/
Chirugie mini-invasive de rapprochement des apophyses epineuses.
Perrin, R., Launois, T., Desbrosse, F. G., Vandeweerd, J. M., & Clegg, P. D. (2008). Chirugie mini-invasive de rapprochement des apophyses epineuses.. Pratique Veterinaire equine, 41, 143-146.
Electrospun nanofibres of polycaprolactone, and their use for tendon regeneration
Bosworth, L., Clegg, P., & Downes, S. (2008). Electrospun nanofibres of polycaprolactone, and their use for tendon regeneration. International Journal of Nano and Biomaterials, 1(3), 263. doi:10.1504/ijnbm.2008.016875
Osmotic regulation of SOX9 in human articular chondrocytes through p38 MAPK mediated mRNA stabilization
Tew, S. R., Mckay, T., Lowe, E., Clegg, P. D., & Hardingham, T. E. (2008). Osmotic regulation of SOX9 in human articular chondrocytes through p38 MAPK mediated mRNA stabilization. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 89 (pp. A26). Retrieved from https://www.webofscience.com/
2007
Biofilms and their relevance to veteninary medicine (Vol 121, Pg 1, 2007)
Clutterbuck, A. L., Woods, E. J., Knottenbelt, D. C., Clegg, P. D., Cochrane, C. A., & Percival, S. L. (2007). Biofilms and their relevance to veteninary medicine (Vol 121, Pg 1, 2007). VETERINARY MICROBIOLOGY, 125(3-4), 390. doi:10.1016/j.vetmic.2007.05.029
Matrix metabolism rate differs in functionally distinct tendons
Birch, H. L., Worboys, S., Eissa, S., Jackson, B., Strassburg, S., & Clegg, P. D. (2008). Matrix metabolism rate differs in functionally distinct tendons. MATRIX BIOLOGY, 27(3), 182-189. doi:10.1016/j.matbio.2007.10.004
SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis
Tew, S. R., Clegg, P. D., Brew, C. J., Redmond, C. M., & Hardingham, T. E. (2007). SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis. ARTHRITIS RESEARCH & THERAPY, 9(5). doi:10.1186/ar2311
Coxofemoral luxation - how does our knowledge of treatment in other species heap us in the horse?
Clegg, P. D., & Comerford, E. J. (2007). Coxofemoral luxation - how does our knowledge of treatment in other species heap us in the horse?. EQUINE VETERINARY EDUCATION, 19(9), 482-483. doi:10.2746/095777307X238525
Stem cells in veterinary medicine - attempts at regenerating equine tendon after injury
Richardson, L. E., Dudhia, J., Clegg, P. D., & Smith, R. (2007). Stem cells in veterinary medicine - attempts at regenerating equine tendon after injury. TRENDS IN BIOTECHNOLOGY, 25(9), 409-416. doi:10.1016/j.tibtech.2007.07.009
Cell phenotypic variation in normal and damaged tendons
Clegg, P. D., Strassburg, S., & Smith, R. K. (2007). Cell phenotypic variation in normal and damaged tendons. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 88(4), 227-235. doi:10.1111/j.1365-2613.2007.00549.x
Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus
Rousseau, K., Kirkham, S., McKane, S., Newton, R., Clegg, P., & Thornton, D. J. (2007). Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 292(6), L1396-L1404. doi:10.1152/ajplung.00444.2006
Biofilms and their relevance to veterinary medicine
Clutterbuck, A. L., Woods, E. J., Knottenbelt, D. C., Clegg, P. D., Cochrane, C. A., & Percival, S. L. (2007). Biofilms and their relevance to veterinary medicine. VETERINARY MICROBIOLOGY, 121(1-2), 1-17. doi:10.1016/j.vetmic.2006.12.029
Reported morbidities following 861 anaesthetics given at four equine hospitals
Senior, J. M., Pinchbeck, G. L., Allister, R., Dugdale, A. H. A., Clark, L., Clutton, R. E., . . . Clegg, P. D. (2007). Reported morbidities following 861 anaesthetics given at four equine hospitals. VETERINARY RECORD, 160(12), 407-408. doi:10.1136/vr.160.12.407
Treatment of recurrent luxation of the shoulder in an alpaca
Vandeweerd, J. M., Clegg, P., Wawra, E., & Dugdale, A. (2007). Treatment of recurrent luxation of the shoulder in an alpaca. VETERINARY RECORD, 160(9), 304-306. doi:10.1136/vr.160.9.304
Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?
Taylor, S. E., Smith, R. K. W., & Clegg, P. D. (2007). Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?. EQUINE VETERINARY JOURNAL, 39(2), 172-180. doi:10.2746/042516407X180868
Endoscopic resection of dorsal spinous processes and interspinous ligament in ten horses
Desbrosse, F. G., Perrin, R., Launois, T., Vandeweerd, J. -M. E., & Clegg, P. D. (2007). Endoscopic resection of dorsal spinous processes and interspinous ligament in ten horses. VETERINARY SURGERY, 36(2), 149-155. doi:10.1111/j.1532-950X.2007.00247.x
) Recurrent luxation of the shoulder in an alpaca treated by greater tubercle osteotomy and bicipital tendon transposition
Vandeweerd, J. M., Dugdale, A., Wawra, E., & Clegg, P. D. (2007). ) Recurrent luxation of the shoulder in an alpaca treated by greater tubercle osteotomy and bicipital tendon transposition. The Veterinary Record, 160(9), 304-306.
An anatomic study of the calcaneal bursae in the horse
Post, E. M., Singer, E. R., & Clegg, P. D. (2007). An anatomic study of the calcaneal bursae in the horse. VETERINARY SURGERY, 36(1), 3-9. doi:10.1111/j.1532-950X.2007.00229.x
An anatomical post mortem study of the calcaneal bursae in the horse
Post, E. M., Singer, E. R., & Clegg, P. D. (2007). An anatomical post mortem study of the calcaneal bursae in the horse. Veterinary Surgery, 36, 3-9.
Innervation and nerve injections of the lumbar spine of the horse: a cadaveric study
Vandeweerd, J. -M., Desbrosse, F., Clegg, P., Hougardy, V., Brock, L., Welch, A., & Cripps, P. (2007). Innervation and nerve injections of the lumbar spine of the horse: a cadaveric study. EQUINE VETERINARY JOURNAL, 39(1), 59-63. doi:10.2746/042516407X153147
Skeletal scintigraphy in the horse: Current indications and validity as a diagnostic test
Archer, D. C., Boswell, J. C., Voute, L. C., & Clegg, P. D. (2007). Skeletal scintigraphy in the horse: Current indications and validity as a diagnostic test. The Veterinary Journal, 173, 33-46.
Skeletal scintigraphy in the horse: Current indications and validity as a diagnostic test
Archer, D. C., Boswell, J. C., Voute, L. C., & Clegg, P. D. (2007). Skeletal scintigraphy in the horse: Current indications and validity as a diagnostic test. VETERINARY JOURNAL, 173(1), 31-44. doi:10.1016/j.tvjl.2005.10.006
2006
Complete and partial hoof wall resection for keratoma removal: Post operative complications and final outcome in 26 horses (1994-2004)
Boys Smith, S. J., Clegg, P. D., Hughes, I., & Singer, E. R. (2006). Complete and partial hoof wall resection for keratoma removal: Post operative complications and final outcome in 26 horses (1994-2004). Handbook of Environmental Chemistry, Volume 5: Water Pollution, 38(2), 127-133.
Assessment of the use of RNA quality metrics for the screening of articular cartilage specimens from clinically normal dogs and dogs with osteoarthritis
Clements, D. N., Vaughan-Thomas, A., Peansukmanee, S., Carter, S. D., Innes, J. E., Ollier, W. E. R., & Clegg, P. D. (2006). Assessment of the use of RNA quality metrics for the screening of articular cartilage specimens from clinically normal dogs and dogs with osteoarthritis. AMERICAN JOURNAL OF VETERINARY RESEARCH, 67(8), 1438-1444. doi:10.2460/ajvr.67.8.1438
TNF-α SNP haplotype frequencies in equidae
Brown, J. J., Ollier, W. E. R., Thomson, W., Matthews, J. B., Carter, S. D., Binns, M., . . . Clegg, P. D. (2006). TNF-α SNP haplotype frequencies in equidae. TISSUE ANTIGENS, 67(5), 377-382. doi:10.1111/j.1399-0039.2006.00581.x
Analysis of horse race videos to identify intra-race risk factors for fatal distal limb fracture
Parkin, T. D. H., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2006). Analysis of horse race videos to identify intra-race risk factors for fatal distal limb fracture. PREVENTIVE VETERINARY MEDICINE, 74(1), 44-55. doi:10.1016/j.prevetmed.2006.01.006
Accuracy of Diagnostic Techniques Used in Investigation of Stifle Lameness in Horses - 40 Cases
Barr, E. D., Pinchbeck, G. L., Clegg, P. D., & Singer, E. R. (2006). Accuracy of Diagnostic Techniques Used in Investigation of Stifle Lameness in Horses - 40 Cases. Equine Veterinary Education, 38(6), 326-332.
Accuracy of diagnostic techniques used in investigation of stifle lameness in horses - 40 cases
Barr, E. D., Pinchbeck, G. L., Clegg, P. D., & Singer, E. R. (2006). Accuracy of diagnostic techniques used in investigation of stifle lameness in horses - 40 cases. EQUINE VETERINARY EDUCATION, 18(6), 326-331. Retrieved from https://www.webofscience.com/
Assessment of the use of RNA quality metrics for the screening of normal and pathological canine articular cartilage samples.
Clements, D. N., Vaughan-Thomas, A., Peansukmanee, S., Carter, S. D., Innes, J. F., Ollier, W. E. R., & Clegg, P. D. (2006). Assessment of the use of RNA quality metrics for the screening of normal and pathological canine articular cartilage samples.. American Journal of Veterinary Research, 67(8), 1438-1444.
Catastrophic fracture of the lateral condyle of the third metacarpus/metatarsus in UK racehorses - fracture descriptions and pre-existing pathology
Parkin, T. D. H., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2006). Catastrophic fracture of the lateral condyle of the third metacarpus/metatarsus in UK racehorses - fracture descriptions and pre-existing pathology. VETERINARY JOURNAL, 171(1), 157-165. doi:10.1016/j.tvjl.2004.10.009
Chondrogenesis in cultured equine chondrocytes - effect of hypoxia, culture conditions and zonal source of chondrocytes
Clegg, P. D., Redmond, C. M., & Hardingham, T. E. (2006). Chondrogenesis in cultured equine chondrocytes - effect of hypoxia, culture conditions and zonal source of chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 87 (pp. A51-A52). Retrieved from https://www.webofscience.com/
Complete and partial hoof wall resection for keratoma removal: post operative complications and final outcome in 26 horses (1994-2004)
Smith, S. J. B., Clegg, P. D., Hughes, I., & Singer, E. R. (2006). Complete and partial hoof wall resection for keratoma removal: post operative complications and final outcome in 26 horses (1994-2004). EQUINE VETERINARY JOURNAL, 38(2), 127-133. doi:10.2746/042516406776563288
Innervation and techniques for injection of lumbar spine in the horse
Vandeweerd, J. M., Desbrosse, F., & Clegg, P. (2006). Innervation and techniques for injection of lumbar spine in the horse. Proceedings SIVE Congress, Bologna, Italy, 1, 00.
Multilineage differentiation potential of equine tendon cells in comparison with bone marrow cells
Strassburg, S., Roger, K. S., Hardingham, T. E., & Clegg, P. D. (2006). Multilineage differentiation potential of equine tendon cells in comparison with bone marrow cells. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 87 (pp. A25). Retrieved from https://www.webofscience.com/
Post anaesthetic colic in horses: a preventable complication?
Senior, J. M., Pinchbeck, G. L., Allister, R., Dugdale, A. H. A., Clark, L., Clutton, R. E., . . . Clegg, P. D. (2006). Post anaesthetic colic in horses: a preventable complication?. EQUINE VETERINARY JOURNAL, 38(5), 479-484. doi:10.2746/042516406778400673
Therapy for osteoarthritis in the horse - How do we know that it works?
Clegg, P. D. (2006). Therapy for osteoarthritis in the horse - How do we know that it works?. VETERINARY JOURNAL, 171(1), 9-10. doi:10.1016/j.tvjl.2005.02.003
2005
Quantitative analysis of voltage-gated potassium currents from primary equine (<i>Equus caballus</i>) and elephant (<i>Loxodonta africana</i>) articular chondrocytes
Mobasheri, A., Gent, T. C., Womack, M. D., Carter, S. D., Clegg, P. D., & Barrett-Jolley, R. (2005). Quantitative analysis of voltage-gated potassium currents from primary equine (<i>Equus caballus</i>) and elephant (<i>Loxodonta africana</i>) articular chondrocytes. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 289(1), R172-R180. doi:10.1152/ajpregu.00710.2004
Nutraceutical therapies for degenerative joint diseases: A critical review
Goggs, R., Vaughan-Thomas, A., Clegg, P. D., Carter, S. D., Innes, J. F., Mobasheri, A., . . . Bondy, C. A. (2005). Nutraceutical therapies for degenerative joint diseases: A critical review. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 45(3), 145-164. doi:10.1080/10408690590956341
Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses
Barr, E. D., Clegg, P. D., Senior, J. M., & Singer, E. R. (2005). Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses. VETERINARY SURGERY, 34(2), 159-166. doi:10.1111/j.1532-950X.2005.00026.x
Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.
Barr, E. D., Clegg, P. D., Mark Senior, J., & Singer, E. R. (2005). Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.. Veterinary surgery : VS, 34(2), 159-166. doi:10.1111/j.1532-950x.2005.00026.x
Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes
Phillips, T., Ferraz, I., Bell, S., Clegg, P. D., Carter, S. D., & Mobasheri, A. (2005). Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes. VETERINARY JOURNAL, 169(2), 216-222. doi:10.1016/j.tvjl.2004.01.026
Analysis of stretch activated ion channels in primary cultures of equine articular chondrocytes
Womack, M. D., Mobasheri, A., Clegg, P. D., Mason, S. L., & Barrett-Jolley, R. (2005). Analysis of stretch activated ion channels in primary cultures of equine articular chondrocytes. In BIOPHYSICAL JOURNAL Vol. 88 (pp. 290A). Retrieved from https://www.webofscience.com/
Effect of age at presentation on outcome following arthroscopic debridement of subchondral cystic lesions of the medial femoral condyle: 85 horses (1993-2003)
Smith, M. A., Walmsley, J. P., Phillips, T. J., Pinchbeck, G. L., Booth, T. M., Greet, T. R. C., . . . Clegg, P. D. (2005). Effect of age at presentation on outcome following arthroscopic debridement of subchondral cystic lesions of the medial femoral condyle: 85 horses (1993-2003). EQUINE VETERINARY JOURNAL, 37(2), 175-180. doi:10.2746/0425164054223741
Increased collagen and matrix metalloproteinase-13 gene expression in post-traumatic equine tendonitis
Clegg, P. D., Strassburg, S., Smith, R. K., Goodship, A., Redmond, C. A., & Hardingham, T. E. (2005). Increased collagen and matrix metalloproteinase-13 gene expression in post-traumatic equine tendonitis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 86 (pp. A84-A85). Retrieved from https://www.webofscience.com/
Increased expression and total activity of collagenase does not correlate with collagen degradation from cytokine-treated equine cartilage explants
Donaldson, F., Vaughan-Thomas, A., Clegg, P. D., Carter, S. D., Mobasheri, A., & Innes, J. F. (2005). Increased expression and total activity of collagenase does not correlate with collagen degradation from cytokine-treated equine cartilage explants. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 86(6), A93. Retrieved from https://www.webofscience.com/
Is it just joint inflammation or is it septic? The nagging worry!
Clegg, P. (2005). Is it just joint inflammation or is it septic? The nagging worry!. EQUINE VETERINARY EDUCATION, 17(4), 210-211. Retrieved from https://www.webofscience.com/
Methicillin-resistant staphylococci in companion animals
Baptiste, K. E., Williams, K., Willams, N. J., Wattret, A., Clegg, P. D., Dawson, S., . . . Hart, C. A. (2005). Methicillin-resistant staphylococci in companion animals. EMERGING INFECTIOUS DISEASES, 11(12), 1942-1944. doi:10.3201/eid1112.050241
Methicillin-resistant staphylococci in companion animals
Baptiste, K. E., Williams, K., Williams, N. J., Wattret, A., Clegg, P. D., Dawson, S., . . . Hart, C. A. (2005). Methicillin-resistant staphylococci in companion animals. Emerging Infectious Diseases, 11(12), 1942-1944.
Methicillin-resistant staphylococci in companion animals
Baptiste, K. E., Williams, K., Williams, N. J., Wattret, A., Clegg, P. D., Dawson, S., . . . Hart, C. A. (2005). Methicillin-resistant staphylococci in companion animals. Emerging Infectious Diseases, 11(12), 1942-1944. Retrieved from http://www.cdc.gov/ncidod/EID/vol11no12/pdfs/05-0241.pdf
Methicillin-resistant staphylococci in companion animals
Baptiste, K. E., Williams, K., Willams, N. J., Wattret, A., Clegg, P. D., Dawson, S., . . . Hart, C. A. (2005). Methicillin-resistant staphylococci in companion animals. Emerg Infect Dis, 11(12), 1942-1944. Retrieved from http://www.ncbi.nlm.nih.gov/
Risk factors for fatal lateral condylar fracture of the third metacarpus/metatarsus in UK racing
Parkin, T. D. H., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2005). Risk factors for fatal lateral condylar fracture of the third metacarpus/metatarsus in UK racing. EQUINE VETERINARY JOURNAL, 37(3), 192-199. doi:10.2746/0425164054530641
2004
Septic tenosynovitis of the tarsal sheath of an Arab gelding and suspected sepsis of the lateral digital flexor tendon subsequent to bacterial peritonitis
Archer, D. C., Clegg, P. D., & Edwards, G. B. (2004). Septic tenosynovitis of the tarsal sheath of an Arab gelding and suspected sepsis of the lateral digital flexor tendon subsequent to bacterial peritonitis. VETERINARY RECORD, 155(16), 485-489. doi:10.1136/vr.155.16.485
Retrospective study of the risk factors and prevalence of colic in horses after orthopaedic surgery
Senior, J. M., Pinchbeck, G. L., Dugdale, A. H. A., & Clegg, P. D. (2004). Retrospective study of the risk factors and prevalence of colic in horses after orthopaedic surgery. VETERINARY RECORD, 155(11), 321-+. doi:10.1136/vr.155.11.321
Aquaporin water channels AQP1 and AQP3, are expressed in equine articular chondrocytes
Mobasheri, A., Trujillo, E., Bell, S., Carter, S. D., Clegg, P. D., Martín-Vasallo, P., & Marples, D. (2004). Aquaporin water channels AQP1 and AQP3, are expressed in equine articular chondrocytes. VETERINARY JOURNAL, 168(2), 143-150. doi:10.1016/j.tvjl.2003.08.001
Cultivation of human tenocytes in high-density culture
Schulze-Tanzil, G., Mobasheri, A., Clegg, P. D., Sendzik, J., John, T., & Shakibaei, M. (2004). Cultivation of human tenocytes in high-density culture. HISTOCHEMISTRY AND CELL BIOLOGY, 122(3), 219-228. doi:10.1007/s00418-004-0694-9
Polymorphisms of the equine major histocompatibility complex class II <i>DRA</i> locus
Brown, J. J., Thomson, W., Clegg, P., Eyre, S., Kennedy, L. J., Matthews, J., . . . Ollier, W. E. R. (2004). Polymorphisms of the equine major histocompatibility complex class II <i>DRA</i> locus. TISSUE ANTIGENS, 64(2), 173-179. doi:10.1111/j.1399-0039.2004.00269.x
Case-control investigation of the factors affecting the risk of horses falling during steeplechase racing in the UK
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. P. (2004). Case-control investigation of the factors affecting the risk of horses falling during steeplechase racing in the UK. VETERINARY RECORD, 155(1), 11-15. doi:10.1136/vr.155.1.11
Risk of fatal distal limb fractures among thoroughbreds involved in the five types of racing in the United Kingdom
Parkin, I. D. H., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2004). Risk of fatal distal limb fractures among thoroughbreds involved in the five types of racing in the United Kingdom. VETERINARY RECORD, 154(16), 493-497. doi:10.1136/vr.154.16.493
Equine welfare: risk of horses falling in the Grand National.
Proudman, C., Pinchbeck, G., Clegg, P., & French, N. (2004). Equine welfare: risk of horses falling in the Grand National.. Nature, 428(6981), 385-386. doi:10.1038/428385a
Treatment of septic common digital extensor tenosynovitis by complete resection in seven horses
Booth, T. M., Abbot, J., Clements, A., Singer, E. R., & Clegg, P. D. (2004). Treatment of septic common digital extensor tenosynovitis by complete resection in seven horses. VETERINARY SURGERY, 33(2), 107-111. doi:10.1111/j.1532-950X.2004.04017.x
Genetic Testing
Ollier, W. E. R., & Clegg, P. D. (2004). Genetic Testing.
A prospective cohort study to investigate risk factors for horse falls in UK hurdle and steeplechase racing
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. P. (2004). A prospective cohort study to investigate risk factors for horse falls in UK hurdle and steeplechase racing. Equine Vet J, 36(7), 595-601. Retrieved from http://www.ncbi.nlm.nih.gov/
A prospective cohort study to investigate risk factors for horse falls in UK hurdle and steeplechase racing
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. P. (2004). A prospective cohort study to investigate risk factors for horse falls in UK hurdle and steeplechase racing. EQUINE VETERINARY JOURNAL, 36(7), 595-601. doi:10.2746/0425164044864552
Chronic equine larninitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes
Mobasheri, A., Critchlow, K., Clegg, R. D., Carter, S. D., & Canessa, C. M. (2004). Chronic equine larninitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes. EQUINE VETERINARY JOURNAL, 36(3), 248-254. doi:10.2746/0425164044877224
Cultivation of human tenocytes in high-density culture
Schulze-Tanzil, G., Mobasheri, A., Clegg, P. D., Sendzik, J., John, T., & Shakibaei, M. (2004). Cultivation of human tenocytes in high-density culture. In OSTEOARTHRITIS AND CARTILAGE Vol. 12 (pp. S131-S132). Retrieved from https://www.webofscience.com/
Horse injuries and racing practices in National Hunt racehorses in the UK: the results of a prospective cohort study
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Stirk, A., Morgan, K. L., & French, N. P. (2004). Horse injuries and racing practices in National Hunt racehorses in the UK: the results of a prospective cohort study. VETERINARY JOURNAL, 167(1), 45-52. doi:10.1016/S1090-0233(03)00141-2
Horse-level risk factors for fatal distal limb fracture in racing Thoroughbreds in the UK
Parkin, T. D. H., Clegg, R. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2004). Horse-level risk factors for fatal distal limb fracture in racing Thoroughbreds in the UK. EQUINE VETERINARY JOURNAL, 36(6), 513-519. doi:10.2746/0425164044877387
Horse-level risk factors for fatal distal limb fracture in racing Thoroughbreds in the UK
Parkin, T. D., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2004). Horse-level risk factors for fatal distal limb fracture in racing Thoroughbreds in the UK. Equine Vet J, 36(6), 513-519. Retrieved from http://www.ncbi.nlm.nih.gov/
Race- and course-level risk factors for fatal distal limb fracture in racing Thoroughbreds
Parkin, T. D. H., Clegg, P. D., French, N. P., Proudman, C. J., Riggs, C. M., Singer, E. R., . . . Morgan, K. L. (2004). Race- and course-level risk factors for fatal distal limb fracture in racing Thoroughbreds. EQUINE VETERINARY JOURNAL, 36(6), 521-526. doi:10.2746/0425164044877332
Unilateral hindlimb swelling may be a sign of serious disseminated neoplasia in horses
Knottenbelt, D. C., & Clegg, P. D. (2004). Unilateral hindlimb swelling may be a sign of serious disseminated neoplasia in horses. EQUINE VETERINARY EDUCATION, 16(1), 7-11. Retrieved from https://www.webofscience.com/
Voltage-gated potassium currents of horse and elephant chondrocytes
Barrett-Jolley, R., Womack, M. D., Clegg, P. D., & Mobasheri, A. (2004). Voltage-gated potassium currents of horse and elephant chondrocytes. In OSTEOARTHRITIS AND CARTILAGE Vol. 12 (pp. S109). Retrieved from https://www.webofscience.com/
Whip use and race progress are associated with horse falls in hurdle and steeplechase racing in the UK
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. R. (2004). Whip use and race progress are associated with horse falls in hurdle and steeplechase racing in the UK. EQUINE VETERINARY JOURNAL, 36(5), 384-389. doi:10.2746/0425164044868387
2003
Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis
Clegg, P. D., & Mobasheri, A. (2003). Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis. VETERINARY JOURNAL, 166(1), 3-4. doi:10.1016/S1090-0233(02)00270-8
Case-control study to investigate risk factors for horse falls in hurdle racing in England and Wales
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. P. (2003). Case-control study to investigate risk factors for horse falls in hurdle racing in England and Wales. VETERINARY RECORD, 152(19), 583-587. doi:10.1136/vr.152.19.583
Differential diagnosis of a swollen hock in the horse
Clegg, P. (2003). Differential diagnosis of a swollen hock in the horse. In Practice, 25(6), 328-341. doi:10.1136/inpract.25.6.328
Primary retroperitoneal tumour in a horse
McKay, J. S., Clegg, P. D., Morthole, V. I., & Blake, C. L. (2003). Primary retroperitoneal tumour in a horse. EQUINE VETERINARY JOURNAL, 35(1), 103-106. doi:10.2746/042516403775467432
Retrospective study of 24 cases of septic calcaneal bursitis in the horse
Post, E. M., Singer, E. R., Clegg, P. D., Smith, R. K., & Cripps, P. J. (2003). Retrospective study of 24 cases of septic calcaneal bursitis in the horse. EQUINE VETERINARY JOURNAL, 35(7), 662-668. doi:10.2746/042516403775696285
2002
Risk factors and sources of variation in horse falls in steeplechase racing in the UK
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., Wood, J. L. N., & French, N. P. (2002). Risk factors and sources of variation in horse falls in steeplechase racing in the UK. PREVENTIVE VETERINARY MEDICINE, 55(3), 179-192. doi:10.1016/S0167-5877(02)00098-3
Subluxation of the left elbow joint in a pony at induction of general anaesthesia
Senior, M., Smith, M., & Clegg, P. (2002). Subluxation of the left elbow joint in a pony at induction of general anaesthesia. VETERINARY RECORD, 151(6), 183-184. doi:10.1136/vr.151.6.183
Horse falls in national hunt racing in the UK: Risk factors and sources of variation
Pinchbeck, G. L., Clegg, P. D., Proudman, C. J., Morgan, K. L., & French, N. P. (2002). Horse falls in national hunt racing in the UK: Risk factors and sources of variation. In SOCIETY FOR VETERINARY EPIDEMIOLOGY AND PREVENTIVE MEDICINE, VICENARY PROCEEDINGS (pp. 84-95). Retrieved from https://www.webofscience.com/
Microscopic localization of active gelatinases in equine osteochondritis dissecans (OCD) cartilage
Al-Hizab, F., Clegg, P. D., Thompson, C. C., & Carter, S. D. (2002). Microscopic localization of active gelatinases in equine osteochondritis dissecans (OCD) cartilage. OSTEOARTHRITIS AND CARTILAGE, 10(8), 653-661. doi:10.1053/joca.2002.0811
Subluxation of the left elbow joint in a pony at induction of general anaesthesia
Senior, M., Smith, M., & Clegg, P. (2002). Subluxation of the left elbow joint in a pony at induction of general anaesthesia. Vet Rec, 151(6), 183-184. Retrieved from http://www.ncbi.nlm.nih.gov/
2001
Treatment of sepsis in the small tarsal joints of 11 horses with gentamicin-impregnated polymethylmethacrylate beads
Booth, T. M., Butson, R. J., Clegg, P. D., Schramme, M. C., & Smith, R. K. (2001). Treatment of sepsis in the small tarsal joints of 11 horses with gentamicin-impregnated polymethylmethacrylate beads. VETERINARY RECORD, 148(12), 376-380. doi:10.1136/vr.148.12.376
Scapulohumeral osteoarthritis in 20 Shetland ponies, miniature horses and falabella ponies
Clegg, P. D., Dyson, S. J., Summerhays, G. E. S., & Schramme, M. C. (2001). Scapulohumeral osteoarthritis in 20 Shetland ponies, miniature horses and falabella ponies. VETERINARY RECORD, 148(6), 175-179. doi:10.1136/vr.148.6.175
Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes
Thompson, C. C., Clegg, P. D., & Carter, S. D. (2001). Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes. Osteoarthritis Cartilage, 9(4), 325-331. Retrieved from http://www.ncbi.nlm.nih.gov/
Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes
Thompson, C. C. M., Clegg, P. D., & Carter, S. D. (2001). Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes. OSTEOARTHRITIS AND CARTILAGE, 9(4), 325-331. doi:10.1053/joca.2000.0392
Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids
Misum, K., Villim, V., Clegg, P. D., Thompson, C. M., & Carter, S. D. (2001). Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids. Osteoarthritis and Cartilage, 9(2), 119-127. doi:10.1053/joca.2000.0367
Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids
Misumi, K., Vilim, V., Clegg, P. D., Thompson, C. C. M., & Carter, S. D. (2001). Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids. OSTEOARTHRITIS AND CARTILAGE, 9(2), 119-127. doi:10.1053/joca.2000.0367
2000
Endoscopic electrosurgical excision of laryngeal granulation tissue in a standing pregnant mare
Booth, T. M., Hainisch, E. K., Knottenbelt, D. C., Edwards, G. B., Clegg, P. D., & Kelly, D. F. (2000). Endoscopic electrosurgical excision of laryngeal granulation tissue in a standing pregnant mare. VETERINARY RECORD, 147(15), 418-420. doi:10.1136/vr.147.15.418
Canine TIMP-2: Purification, characterization and molecular detection
Bee, A., Barnes, A., Jones, M. D., Robertson, D. H. L., Clegg, P. D., & Carter, S. D. (2000). Canine TIMP-2: Purification, characterization and molecular detection. VETERINARY JOURNAL, 160(2), 126-134. Retrieved from https://www.webofscience.com/
Resection of the common digital extensor tendon in a gelding
Booth, T. M., Clegg, P. D., Singer, E. R., & Cheeseman, M. T. (2000). Resection of the common digital extensor tendon in a gelding. VETERINARY RECORD, 146(13), 373-376. doi:10.1136/vr.146.13.373
Canine TIMP-2: purification, characterization and molecular detection.
Bee, A., Barnes, A., Jones, M. D., Robertson, D. H., Clegg, P. D., & Carter, S. D. (2000). Canine TIMP-2: purification, characterization and molecular detection.. Veterinary journal (London, England : 1997), 160(2), 126-134. doi:10.1053/tvjl.2000.0467
Clinical findings associated with chronic ischial fracture in a gelding
Booth, T. M., & Clegg, P. D. (2000). Clinical findings associated with chronic ischial fracture in a gelding. AUSTRALIAN VETERINARY JOURNAL, 78(10), 681-682. doi:10.1111/j.1751-0813.2000.tb10403.x
Drugs used to treat osteoarthritis in the horse
Clegg, P., & Booth, T. (2000). Drugs used to treat osteoarthritis in the horse. In Practice, 22(10), 594-603. doi:10.1136/inpract.22.10.594
Matrix metalloproteinases 2 and 9 activity in bovine synovial fluids
Arican, M., Coughlan, A. R., Clegg, D., & Carter, S. D. (2000). Matrix metalloproteinases 2 and 9 activity in bovine synovial fluids. JOURNAL OF VETERINARY MEDICINE SERIES A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE, 47(8), 449-456. doi:10.1046/j.1439-0442.2000.00291.x
1999
Matrix metalloproteinase-2 and-9 are activated in joint diseases
Clegg, P. D., & Carter, S. D. (1999). Matrix metalloproteinase-2 and-9 are activated in joint diseases. EQUINE VETERINARY JOURNAL, 31(4), 324-330. doi:10.1111/j.2042-3306.1999.tb03825.x
Molecular studies of matrix metalloproteinases and tissue inhibitors of metalloproteinases in equine joints
Clegg, P. D., Radford, A. D., & Carter, S. D. (1999). Molecular studies of matrix metalloproteinases and tissue inhibitors of metalloproteinases in equine joints. VETERINARY JOURNAL, 157(3), 336-338. doi:10.1053/tvjl.1998.0328
1998
The effect of drugs commonly used in the treatment of equine articular disorders on the activity of equine matrix metalloproteinase-2 and 9
Clegg, P. D., Jones, M. D., & Carter, S. D. (1998). The effect of drugs commonly used in the treatment of equine articular disorders on the activity of equine matrix metalloproteinase-2 and 9. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 21(5), 406-413. Retrieved from https://www.webofscience.com/
Equine TIMP-1 and TIMP-2: Identification, activity and cellular sources
Clegg, P. D., Coughlan, A. R., & Carter, S. D. (1998). Equine TIMP-1 and TIMP-2: Identification, activity and cellular sources. EQUINE VETERINARY JOURNAL, 30(5), 416-423. doi:10.1111/j.2042-3306.1998.tb04512.x
1997
Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints
Clegg, P. D., Burke, R. M., Coughlan, A. R., Riggs, C. M., & Carter, S. D. (1997). Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints. EQUINE VETERINARY JOURNAL, 29(5), 335-342. doi:10.1111/j.2042-3306.1997.tb03136.x
Matrix metalloproteinases 2 and 9 in equine synovial fluids
Clegg, P. D., Coughlan, A. R., Riggs, C. M., & Carter, S. D. (1997). Matrix metalloproteinases 2 and 9 in equine synovial fluids. EQUINE VETERINARY JOURNAL, 29(5), 343-348. doi:10.1111/j.2042-3306.1997.tb03137.x
Osteoarthritis - what hope for effective therapy?
Clegg, P. D., Carter, S. D., & Riggs, C. M. (1997). Osteoarthritis - what hope for effective therapy?. EQUINE VETERINARY JOURNAL, 29(5), 331-332. doi:10.1111/j.2042-3306.1997.tb03134.x
1996
Treatment of a coxofemoral luxation secondary to upward fixation of the patella in a Shetland pony.
Clegg, P. D., & Butson, R. J. (1996). Treatment of a coxofemoral luxation secondary to upward fixation of the patella in a Shetland pony.. The Veterinary record, 138(6), 134-137. doi:10.1136/vr.138.6.134
1995
Desflurane in equine anaesthesia: a preliminary trial.
Jones, N. Y., Clarke, K. W., & Clegg, P. D. (1995). Desflurane in equine anaesthesia: a preliminary trial.. The Veterinary record, 137(24), 618-620.
Idiopathic infective arthritis of the coxofemoral joint in a mature horse.
Clegg, P. D. (1995). Idiopathic infective arthritis of the coxofemoral joint in a mature horse.. The Veterinary record, 137(18), 460-464. doi:10.1136/vr.137.18.460
1993
Alveolar rhabdomyosarcoma: an unusual cause of lameness in a pony.
Clegg, P. D., & Coumbe, A. (1993). Alveolar rhabdomyosarcoma: an unusual cause of lameness in a pony.. Equine veterinary journal, 25(6), 547-549. doi:10.1111/j.2042-3306.1993.tb03012.x