Publications
2024
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
Shepherd, M. J., Fu, T., Harrington, N. E., Kottara, A., Cagney, K., Chalmers, J. D., . . . Brockhurst, M. A. (n.d.). Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance. Nature Reviews Microbiology. doi:10.1038/s41579-024-01041-1
Global genomic diversity of Pseudomonas aeruginosa in bronchiectasis
Harrington, N. E., Kottara, A., Cagney, K., Shepherd, M. J., Grimsey, E. M., Fu, T., . . . Paterson, S. (2024). Global genomic diversity of Pseudomonas aeruginosa in bronchiectasis. Journal of Infection, 106275. doi:10.1016/j.jinf.2024.106275
2023
Combining SNAPs with antibiotics shows enhanced synergistic efficacy against S. <i>aureus</i> and P. <i>aeruginosa</i> biofilms (vol 9, 36, 2023)
Maset, R. G., Hapeshi, A., Lapage, J., Harrington, N., Littler, J., Perrier, S., & Harrison, F. (2023). Combining SNAPs with antibiotics shows enhanced synergistic efficacy against S. <i>aureus</i> and P. <i>aeruginosa</i> biofilms (vol 9, 36, 2023). NPJ BIOFILMS AND MICROBIOMES, 9(1). doi:10.1038/s41522-023-00407-2
Combining SNAPs with antibiotics shows enhanced synergistic efficacy against <i>S. aureus</i> and <i>P. aeruginosa</i> biofilms
Maset, R. G., Hapeshi, A., Lapage, J., Harrington, N., Littler, J., Perrier, S., & Harrison, F. (2023). Combining SNAPs with antibiotics shows enhanced synergistic efficacy against <i>S. aureus</i> and <i>P. aeruginosa</i> biofilms. NPJ BIOFILMS AND MICROBIOMES, 9(1). doi:10.1038/s41522-023-00401-8
2022
<i>Pseudomonas aeruginosa</i> transcriptome analysis in a cystic fibrosis lung model reveals metabolic changes accompanying biofilm maturation and increased antibiotic tolerance over time
Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an <i>Ex Vivo</i> Pig Model of the Cystic Fibrosis Lung.
Harrington, N. E., Littler, J. L., & Harrison, F. (2022). Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an <i>Ex Vivo</i> Pig Model of the Cystic Fibrosis Lung.. Applied and environmental microbiology, 88(3), e0178921. doi:10.1128/aem.01789-21
2021
Transcriptome analysis of<i>Pseudomonas aeruginosa</i>biofilm infection in an<i>ex vivo</i>pig model of the cystic fibrosis lung
Antibiotic Efficacy Testing in an Ex vivo Model of <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> Biofilms in the Cystic Fibrosis Lung
Harrington, N. E., Sweeney, E., Alav, I., Allen, F., Moat, J., & Harrison, F. (n.d.). Antibiotic Efficacy Testing in an Ex vivo Model of <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> Biofilms in the Cystic Fibrosis Lung. Journal of Visualized Experiments, (167). doi:10.3791/62187-v
Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung.
Harrington, N. E., Sweeney, E., Alav, I., Allen, F., Moat, J., & Harrison, F. (2021). Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung.. Journal of visualized experiments : JoVE, (167). doi:10.3791/62187
An <i>ex vivo</i> cystic fibrosis model recapitulates key clinical aspects of chronic <i>Staphylococcus aureus</i> infection.
Sweeney, E., Harrington, N. E., Harley Henriques, A. G., Hassan, M. M., Crealock-Ashurst, B., Smyth, A. R., . . . Harrison, F. (2021). An <i>ex vivo</i> cystic fibrosis model recapitulates key clinical aspects of chronic <i>Staphylococcus aureus</i> infection.. Microbiology (Reading, England), 167(1). doi:10.1099/mic.0.000987
2020
Building a better biofilm - Formation of <i>in vivo</i>-like biofilm structures by <i>Pseudomonas aeruginosa</i> in a porcine model of cystic fibrosis lung infection.
Harrington, N. E., Sweeney, E., & Harrison, F. (2020). Building a better biofilm - Formation of <i>in vivo</i>-like biofilm structures by <i>Pseudomonas aeruginosa</i> in a porcine model of cystic fibrosis lung infection.. Biofilm, 2, 100024. doi:10.1016/j.bioflm.2020.100024
Predicting antibiotic-associated virulence of<i>Pseudomonas aeruginosa</i>using an<i>ex-vivo</i>lung biofilm model
Predicting Antibiotic-Associated Virulence of <i>Pseudomonas aeruginosa</i> Using an <i>ex vivo</i> Lung Biofilm Model.
Hassan, M. M., Harrington, N. E., Sweeney, E., & Harrison, F. (2020). Predicting Antibiotic-Associated Virulence of <i>Pseudomonas aeruginosa</i> Using an <i>ex vivo</i> Lung Biofilm Model.. Frontiers in microbiology, 11, 568510. doi:10.3389/fmicb.2020.568510