Publications

Selected publications

Circulating Proteome for Pulmonary Nodule Malignancy. (Journal article - 2023)
Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis (Journal article - 2021)
Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation (Journal article - 2021)
Plasma protein biomarkers for early prediction of lung cancer (Journal article - 2023)
Unique volatolomic signatures of TP53 and KRAS in lung cells (Journal article - 2014)
A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article - 2013)
Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response (Journal article - 2019)
Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer (Journal article - 2008)
Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study (Journal article - 2007)
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours (Journal article - 1996)

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2024

Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers.

DOI: 10.1101/2024.06.26.24309127
: Preprint

EP.13D.12 International Consortium Real-World Outcomes in Extensive Disease Small Cell Lung Cancer Compared to IMPOWER133 And CASPIAN

Khan, S., Hueniken, K., Brown, C. M., Tan, K., Wenzlaff, A. S., Fernandez-Tardon, G., . . . Liu, G. (2024). EP.13D.12 International Consortium Real-World Outcomes in Extensive Disease Small Cell Lung Cancer Compared to IMPOWER133 And CASPIAN. In Journal of Thoracic Oncology Vol. 19 (pp. S679-S680). Elsevier BV. doi:10.1016/j.jtho.2024.09.1286

DOI: 10.1016/j.jtho.2024.09.1286
: Conference Paper

MA17.03 30 Years of International Real World Outcomes in Patients with Limited Disease Small Cell Lung Cancer

Khan, S., Hueniken, K., Brown, C. M., Tan, K., Wenzlaff, A. S., Fernandez-Tardon, G., . . . Liu, G. (2024). MA17.03 30 Years of International Real World Outcomes in Patients with Limited Disease Small Cell Lung Cancer. In Journal of Thoracic Oncology Vol. 19 (pp. S123-S124). Elsevier BV. doi:10.1016/j.jtho.2024.09.222

DOI: 10.1016/j.jtho.2024.09.222
: Conference Paper

On the informative value of community-based indoor radon values in relation to lung cancer.

Rosenberger, A., Bickeböller, H., Christiani, D. C., Liu, G., Schabath, M. B., Duarte, L. F., . . . Hung, R. J. (2024). On the informative value of community-based indoor radon values in relation to lung cancer.. Cancer medicine, 13(16), e70126. doi:10.1002/cam4.70126

DOI: 10.1002/cam4.70126
: Journal article

Retrospective evaluation of plasma protein tumour markers for early lung cancer detection

Davies, M. P. A., Kolamunnage-Dona, R., Phillips, S., Lambert, A., Tate, S., & Field, J. K. (2024). Retrospective evaluation of plasma protein tumour markers for early lung cancer detection. BJC Reports, 2(1). doi:10.1038/s44276-024-00082-6

DOI: 10.1038/s44276-024-00082-6
: Journal article

Impact of single round of low dose CT lung cancer screening on cause of mortality in different socio-economic groups: a post-hoc analysis of long-term follow-up of the UKLS trial.

Davies, M. P. A., Vulkan, D., Gabe, R., Duffy, S. W., & Field, J. K. (2024). Impact of single round of low dose CT lung cancer screening on cause of mortality in different socio-economic groups: a post-hoc analysis of long-term follow-up of the UKLS trial.. The Lancet regional health. Europe, 42, 100936. doi:10.1016/j.lanepe.2024.100936

DOI: 10.1016/j.lanepe.2024.100936
: Journal article

Novel Transcriptional and DNA Methylation Abnormalities of SORT1 Gene in Non-Small Cell Lung Cancer.

Acha-Sagredo, A., Wilson, C. M., Garcia Bediaga, N., Kalirai, H., Davies, M. P. A., Coupland, S. E., . . . Liloglou, T. (2024). Novel Transcriptional and DNA Methylation Abnormalities of SORT1 Gene in Non-Small Cell Lung Cancer.. Cancers, 16(11), 2154. doi:10.3390/cancers16112154

DOI: 10.3390/cancers16112154
: Journal article

Lung cancer in ever- and never-smokers: findings from multi-population GWAS studies.

Li, Y., Xiao, X., Li, J., Han, Y., Cheng, C., Fernandes, G. F., . . . Amos, C. I. (2024). Lung cancer in ever- and never-smokers: findings from multi-population GWAS studies.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. doi:10.1158/1055-9965.epi-23-0613

DOI: 10.1158/1055-9965.epi-23-0613
: Journal article

2023

Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls.

Zhao, X., Yang, M., Fan, J., Wang, M., Wang, Y., Qin, N., . . . Dai, J. (2023). Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls.. Cancer. doi:10.1002/cncr.35130

DOI: 10.1002/cncr.35130
: Journal article

Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer.

Xu, J., Xu, W., Choi, J., Brhane, Y., Christiani, D. C., Kothari, J., . . . Briollais, L. (2023). Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer.. PLoS genetics, 19(9), e1010902. doi:10.1371/journal.pgen.1010902

DOI: 10.1371/journal.pgen.1010902
: Journal article

Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies

Fares, A. F., Li, Y., Jiang, M., Brown, M. C., Lam, A. C. L., Aggarwal, R., . . . Liu, G. (2023). Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies. LANCET PUBLIC HEALTH, 8(9), E691-E700. Retrieved from https://www.webofscience.com/

: Journal article

Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications

Abdellatif, A. A. H., Scagnetti, G., Younis, M. A., Bouazzaoui, A., Tawfeek, H. M., Aldosari, B. N., . . . Saleem, I. (2023). Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications. COLLOIDS AND SURFACES B-BIOINTERFACES, 229. doi:10.1016/j.colsurfb.2023.113466

DOI: 10.1016/j.colsurfb.2023.113466
: Journal article

Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk.

Luyapan, J., Bossé, Y., Li, Z., Xiao, X., Rosenberger, A., Hung, R. J., . . . Amos, C. I. (2023). Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk.. Human molecular genetics, ddad095. doi:10.1093/hmg/ddad095

DOI: 10.1093/hmg/ddad095
: Journal article

Plasma protein biomarkers for early prediction of lung cancer

Davies, M. P. A., Sato, T., Ashoor, H., Hou, L., Liloglou, T., Yang, R., & Field, J. K. (2023). Plasma protein biomarkers for early prediction of lung cancer. EBIOMEDICINE, 93. doi:10.1016/j.ebiom.2023.104686

DOI: 10.1016/j.ebiom.2023.104686
: Journal article

Circulating Proteome for Pulmonary Nodule Malignancy.

Khodayari Moez, E., Warkentin, M. T., Brhane, Y., Lam, S., Field, J. K., Liu, G., . . . Hung, R. J. (2023). Circulating Proteome for Pulmonary Nodule Malignancy.. Journal of the National Cancer Institute, djad122. doi:10.1093/jnci/djad122

DOI: 10.1093/jnci/djad122
: Journal article

Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis.

Cheng, C., Hong, W., Li, Y., Xiao, X., McKay, J., Han, Y., . . . INTEGRAL-ILCCO lung cancer consortium. (2023). Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, S1556-0864(23)00527-0. doi:10.1016/j.jtho.2023.05.001

DOI: 10.1016/j.jtho.2023.05.001
: Journal article

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program

Robbins, H. A., Alcala, K., Moez, E. K., Guida, F., Thomas, S., Zahed, H., . . . Hung, R. J. (2023). Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program. ANNALS OF EPIDEMIOLOGY, 77, 1-12. doi:10.1016/j.annepidem.2022.10.014

DOI: 10.1016/j.annepidem.2022.10.014
: Journal article

On the Non-Linearity of Radon-Induced Lung Cancer

DOI: 10.2139/ssrn.4347965
: Preprint

2022

EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups

Davies, M. P. A., Vulkan, D., Gabe, R., Duffy, S. W., & Field, J. K. (2022). EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups. Journal of Thoracic Oncology, 17(9), S190. doi:10.1016/j.jtho.2022.07.318

DOI: 10.1016/j.jtho.2022.07.318
: Journal article

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

Li, Y., Xiao, X., Li, J., Byun, J., Cheng, C., Bosse, Y., . . . Amos, C. I. (2022). Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk. HUMAN MOLECULAR GENETICS, 31(16), 2831-2843. doi:10.1093/hmg/ddac030

DOI: 10.1093/hmg/ddac030
: Journal article

On the non-linearity of radon-induced lung cancer

DOI: 10.21203/rs.3.rs-1933741/v1
: Preprint

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program

DOI: 10.1101/2022.03.21.22272544
: Preprint

Impact of risk-based low dose CT screening on different socio-economic groups

Davies, M., Vulkan, D., Gabe, R., Duffy, S., & Field, J. (2022). Impact of risk-based low dose CT screening on different socio-economic groups. In Lung Cancer Vol. 165 (pp. S20). Elsevier BV. doi:10.1016/s0169-5002(22)00088-5

DOI: 10.1016/s0169-5002(22)00088-5
: Conference Paper

Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Rosenberger, A., Muttray, N., Hung, R. J., Christiani, D. C., Caporaso, N. E., Liu, G., . . . Bickeboeller, H. (2022). Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer. EUROPEAN JOURNAL OF MEDICAL RESEARCH, 27(1). doi:10.1186/s40001-022-00638-7

DOI: 10.1186/s40001-022-00638-7
: Journal article

Iam hiQ-a novel pair of accuracy indices for imputed genotypes

Rosenberger, A., Tozzi, V., Bickeboeller, H., & Consortium, I. N. T. E. G. R. A. L. -I. L. C. C. O. (2022). Iam hiQ-a novel pair of accuracy indices for imputed genotypes. BMC BIOINFORMATICS, 23(1). doi:10.1186/s12859-022-04568-3

DOI: 10.1186/s12859-022-04568-3
: Journal article

Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data.

Schmid, S., Jiang, M., Brown, M. C., Fares, A., Garcia, M., Soriano, J., . . . Liu, G. (2022). Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. doi:10.1158/1055-9965.epi-21-0747

DOI: 10.1158/1055-9965.epi-21-0747
: Journal article

Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups

Davies, M. P. A., Vulkan, D., Gabe, R., Duffy, S. W., & Field, J. K. (2022). Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups. In JOURNAL OF THORACIC ONCOLOGY Vol. 17 (pp. S190). Retrieved from https://www.webofscience.com/

: Conference Paper

2021

Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis

Field, J. K., Vulkan, D., Davies, M. P. A., Baldwin, D. R., Brain, K. E., Devaraj, A., . . . Duffy, S. W. (2021). Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis. LANCET REGIONAL HEALTH-EUROPE, 10. doi:10.1016/j.lanepe.2021.100179

DOI: 10.1016/j.lanepe.2021.100179
: Journal article

OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis

Field, J., Vulkan, D., Davies, M., Gabe, R., & Duffy, S. (2021). OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis. In Journal of Thoracic Oncology Vol. 16 (pp. S882). Elsevier BV. doi:10.1016/j.jtho.2021.08.098

DOI: 10.1016/j.jtho.2021.08.098
: Conference Paper

Gene-gene Interaction of AhR with and within the Wnt Cascade Affects Susceptibility to Lung Cancer

DOI: 10.21203/rs.3.rs-658360/v2
: Preprint

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

DOI: 10.21203/rs.3.rs-647012/v1
: Preprint

Gene-gene Interaction of AhR With and Within the Wnt Cascade Affects Susceptibility to Lung Cancer

DOI: 10.21203/rs.3.rs-658360/v1
: Preprint

Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium

Guha, N., Bouaoun, L., Kromhout, H., Vermeulen, R., Bruening, T., Behrens, T., . . . Olsson, A. (2021). Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 78(4), 269-278. doi:10.1136/oemed-2020-106770

DOI: 10.1136/oemed-2020-106770
: Journal article

FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC

Haragan, A., Nekolla, K., Kapil, A., Brieu, N., Widmaier, M., Budco, A., . . . Gosney, J. (2021). FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC. In Journal of Thoracic Oncology Vol. 16 (pp. S203). Elsevier BV. doi:10.1016/j.jtho.2021.01.102

DOI: 10.1016/j.jtho.2021.01.102
: Conference Paper

FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People

Field, J., Vulkan, D., Davies, M., Duffy, S., & Gabe, R. (2021). FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People. In Journal of Thoracic Oncology Vol. 16 (pp. S212). Elsevier BV. doi:10.1016/j.jtho.2021.01.119

DOI: 10.1016/j.jtho.2021.01.119
: Conference Paper

Rare deleterious germline variants and risk of lung cancer

Liu, Y., Xia, J., McKay, J., Tsavachidis, S., Xiao, X., Spitz, M. R., . . . Amos, C. I. (2021). Rare deleterious germline variants and risk of lung cancer. NPJ PRECISION ONCOLOGY, 5(1). doi:10.1038/s41698-021-00146-7

DOI: 10.1038/s41698-021-00146-7
: Journal article

Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation

Field, J. K., Vulkan, D., Davies, M. P. A., Duffy, S. W., & Gabe, R. (2021). Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation. THORAX, 76(2), 161-168. doi:10.1136/thoraxjnl-2020-215158

DOI: 10.1136/thoraxjnl-2020-215158
: Journal article

The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients

Jiang, M., Fares, A. F., Shepshelovich, D., Yang, P., Christiani, D., Zhang, J., . . . Liu, G. (2021). The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients. Lung Cancer, 152, 58-65. doi:10.1016/j.lungcan.2020.11.029

DOI: 10.1016/j.lungcan.2020.11.029
: Journal article

2020

Protein-altering germline mutations implicate novel genes related to lung cancer development

Ji, X., Mukherjee, S., Landi, M. T., Bosse, Y., Joubert, P., Zhu, D., . . . Amos, C. I. (2020). Protein-altering germline mutations implicate novel genes related to lung cancer development. NATURE COMMUNICATIONS, 11. doi:10.1038/s41467-020-15905-6

DOI: 10.1038/s41467-020-15905-6
: Journal article

Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis

Acha-Sagredo, A., Uko, B., Pantazi, P., Bediaga, N., Moschandrea, C., Rainbow, L., . . . Liloglou, T. (2020). Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. British Journal of Cancer, 122(7), 1050-1058. doi:10.1038/s41416-020-0742-9

DOI: 10.1038/s41416-020-0742-9
: Journal article

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Kachuri, L., Johansson, M., Rashkin, S. R., Graff, R. E., Bosse, Y., Manem, V., . . . Hung, R. J. (2020). Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-019-13855-2

DOI: 10.1038/s41467-019-13855-2
: Journal article

2019

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review

Cheng, Y. I., Gan, Y. C., Liu, D., Davies, M. P. A., Li, W. M., & Field, J. K. (2019). Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review. BMC CANCER, 19(1). doi:10.1186/s12885-019-6317-6

DOI: 10.1186/s12885-019-6317-6
: Journal article

The Role of Autophagy in Lung Disease

Davies, M. P. A., & Wilson, C. M. (2016). The Role of Autophagy in Lung Disease. In AUTOPHAGY IN CURRENT TRENDS IN CELLULAR PHYSIOLOGY AND PATHOLOGY (pp. 267-285). doi:10.5772/64167

DOI: 10.5772/64167
: Chapter

Implementation Planning of Lung Cancer Screening in China

Cheng, Y., Davies, M., Liu, D., Li, W., & Field, J. (2019). Implementation Planning of Lung Cancer Screening in China. In JOURNAL OF THORACIC ONCOLOGY Vol. 14 (pp. S1008). doi:10.1016/j.jtho.2019.08.2223

DOI: 10.1016/j.jtho.2019.08.2223
: Conference Paper

Pathogenic Germline Rare Variants and Risk of Lung Cancer

Liu, Y., Mckay, J., Xiao, X., Field, J., Davies, M., Brennan, P., . . . Amos, C. (2019). Pathogenic Germline Rare Variants and Risk of Lung Cancer. In JOURNAL OF THORACIC ONCOLOGY Vol. 14 (pp. S689-S690). doi:10.1016/j.jtho.2019.08.1465

DOI: 10.1016/j.jtho.2019.08.1465
: Conference Paper

Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium

Shepshelovich, D., Xu, W., Lu, L., Fares, A., Yang, P., Christiani, D., . . . Hung, R. J. (2019). Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium. JOURNAL OF THORACIC ONCOLOGY, 14(9), 1594-1607. doi:10.1016/j.jtho.2019.05.031

DOI: 10.1016/j.jtho.2019.05.031
: Journal article

Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response

Haragan, A., Field, J. K., Davies, M. P. A., Escriu, C., Gruver, A., & Gosney, J. R. (2019). Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response. Lung Cancer, 134, 79-84. doi:10.1016/j.lungcan.2019.06.005

DOI: 10.1016/j.lungcan.2019.06.005
: Journal article

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., . . . Gorlova, O. Y. (2019). Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. JOURNAL OF THORACIC ONCOLOGY, 14(8), 1360-1369. doi:10.1016/j.jtho.2019.04.008

DOI: 10.1016/j.jtho.2019.04.008
: Journal article

Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer

Kachuri, L., Helby, J., Bojesen, S. E., Christiani, D. C., Su, L., Wu, X., . . . Hung, R. J. (2019). Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 28(7), 1228-1237. doi:10.1158/1055-9965.EPI-18-1215

DOI: 10.1158/1055-9965.EPI-18-1215
: Journal article

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Kachuri, L., Johansson, M., Rashkin, S., Graff, R., Bossé, Y., Manem, V., . . . Hung, R. (2019). Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility: bioRxiv. doi:10.1101/635318

DOI: 10.1101/635318
: Report

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis

Zhu, Y., Wei, Y., Zhang, R., Dong, X., Shen, S., Zhao, Y., . . . Christiani, D. C. (2019). Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 28(5), 935-942. doi:10.1158/1055-9965.EPI-18-0356

DOI: 10.1158/1055-9965.EPI-18-0356
: Journal article

PD-L1 Expression Heterogeneity in NSCLC: Accuracy and Reliability of Using Primary Lung Tumour Versus Metastatic Lymph Node Deposits

Haragan, A. K., Field, J. K., Davies, M. P. A., Escriu, C., Gruver, A., & Gosney, J. R. (2019). PD-L1 Expression Heterogeneity in NSCLC: Accuracy and Reliability of Using Primary Lung Tumour Versus Metastatic Lymph Node Deposits. In JOURNAL OF PATHOLOGY Vol. 248 (pp. S11). Retrieved from https://www.webofscience.com/

: Conference Paper

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases

Haragan, A., Gosney, J., Field, J., Davies, M., Escriu, C., & Gruver, A. (2019). PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases. In Journal of Pathology Vol. 248 (pp. S11). Wiley-Blackwell.

: Conference Paper

Implementation planning for lung cancer screening in China

Cheng, Y. I., Davies, M. P. A., Liu, D., Li, W., & Field, J. K. (2019). Implementation planning for lung cancer screening in China. PRECISION CLINICAL MEDICINE, 2(1), 13-44. doi:10.1093/pcmedi/pbz002

DOI: 10.1093/pcmedi/pbz002
: Journal article

Lung cancer screening programmes: landscape in China

Cheng, Y., Davies, M. P. A., Li, W., & Field, J. K. (2019). Lung cancer screening programmes: landscape in China. In LUNG CANCER Vol. 127 (pp. S60-S61). doi:10.1016/S0169-5002(19)30188-6

DOI: 10.1016/S0169-5002(19)30188-6
: Conference Paper

Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci.

Dai, J., Li, Z., Amos, C. I., Hung, R. J., Tardon, A., Andrew, A., . . . Shen, H. (2019). Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci.. Carcinogenesis. doi:10.1093/carcin/bgy187

DOI: 10.1093/carcin/bgy187
: Journal article

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases

Haragan, A., Gosney, J., Field, J. K., Davies, M., Escriu, C., & Gruver, A. (2019). PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases. In LUNG CANCER Vol. 127 (pp. S25). doi:10.1016/S0169-5002(19)30106-0

DOI: 10.1016/S0169-5002(19)30106-0
: Conference Paper

2018

Digital Core Needle-Biopsy to Assess PD-L1 Expression in Non-Small Cell Lung Cancer: Optimal Sampling and Need for Re-Biopsy

Haragan, A., Field, J., Davies, M., Escriu, C., Gruver, A., & Gosney, J. (2018). Digital Core Needle-Biopsy to Assess PD-L1 Expression in Non-Small Cell Lung Cancer: Optimal Sampling and Need for Re-Biopsy. In JOURNAL OF THORACIC ONCOLOGY Vol. 13 (pp. S534-S535). doi:10.1016/j.jtho.2018.08.739

DOI: 10.1016/j.jtho.2018.08.739
: Conference Paper

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer

Liu, Y., Lusk, C. M., Cho, M. H., Silverman, E. K., Qiao, D., Zhang, R., . . . Spitz, M. R. (2018). Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 13(10), 1483-1495. doi:10.1016/j.jtho.2018.06.016

DOI: 10.1016/j.jtho.2018.06.016
: Journal article

Utilising Heterogeneity: Using a Digital Database of Lung Cancers and Immune Profile to Complement Subjective Assessment

Haragan, A., Field, J., Davies, M., Escriu, C., Gruver, A., & Gosney, J. (2018). Utilising Heterogeneity: Using a Digital Database of Lung Cancers and Immune Profile to Complement Subjective Assessment. In JOURNAL OF THORACIC ONCOLOGY Vol. 13 (pp. S768). doi:10.1016/j.jtho.2018.08.1316

DOI: 10.1016/j.jtho.2018.08.1316
: Conference Paper

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

Ferreiro-Iglesias, A., Lesseur, C., McKay, J., Hung, R. J., Han, Y., Zong, X., . . . Brennan, P. (2018). Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. NATURE COMMUNICATIONS, 9, 12 pages. doi:10.1038/s41467-018-05890-2

DOI: 10.1038/s41467-018-05890-2
: Journal article

2017

Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium

Lohavanichbutr, P., Sakoda, L. C., Amos, C. I., Arnold, S. M., Christiani, D. C., Davies, M. P. A., . . . Chen, C. (2017). Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium. CLINICAL CANCER RESEARCH, 23(24), 7550-7557. doi:10.1158/1078-0432.CCR-17-1401

DOI: 10.1158/1078-0432.CCR-17-1401
: Journal article

Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium

Wang, T., Moon, J. -Y., Wu, Y., Amos, C. I., Hung, R. J., Tardon, A., . . . Ho, G. Y. F. (2017). Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium. PLOS ONE, 12(9). doi:10.1371/journal.pone.0185660

DOI: 10.1371/journal.pone.0185660
: Journal article

Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Lohavanichbutr, P., Sakoda, L. C., Amos, C. I., Arnold, S. M., Christiani, D. C., Davies, M. P., . . . Chen, C. (2017). Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium. In CANCER RESEARCH Vol. 77. doi:10.1158/1538-7445.AM2017-2248

DOI: 10.1158/1538-7445.AM2017-2248
: Conference Paper

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

McKay, J. D., Hung, R. J., Han, Y., Zong, X., Carreras-Torres, R., Christiani, D. C., . . . Field, J. K. (2017). Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.. Nature Genetics, 49(7), 1126-1132. doi:10.1038/ng.3892

DOI: 10.1038/ng.3892
: Journal article

AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer

Al-Khafaji, A. S. K., Marcus, M. W., Davies, M. P. A., Risk, J. M., Shaw, R. J., Field, J. K., & Liloglou, T. (2017). AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer. Oncology letters, 13(6), 4463-4468. doi:10.3892/ol.2017.6012

DOI: 10.3892/ol.2017.6012
: Journal article

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

Carreras-Torres, R., Johansson, M., Haycock, P. C., Wade, K. H., Relton, C. L., Martin, R. M., . . . Brennan, P. (2017). Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study. PLOS ONE, 12(6). doi:10.1371/journal.pone.0177875

DOI: 10.1371/journal.pone.0177875
: Journal article

Aurora B expression modulates paclitaxel response in non-small cell lung cancer.

Al-Khafaji, A. S., Davies, M. P., Risk, J. M., Marcus, M. W., Koffa, M., Gosney, J. R., . . . Liloglou, T. (2017). Aurora B expression modulates paclitaxel response in non-small cell lung cancer.. British journal of cancer, 116(05), 592-599. doi:10.1038/bjc.2016.453

DOI: 10.1038/bjc.2016.453
: Journal article

The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer

Meyer, M., Bell, T., Sussman, D., Wilbur, D., Presley, C., Hayenga, J., . . . Nelson, A. (2017). The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer. In JOURNAL OF THORACIC ONCOLOGY Vol. 12 (pp. S343-S344). doi:10.1016/j.jtho.2016.11.375

DOI: 10.1016/j.jtho.2016.11.375
: Conference Paper

2016

The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study

Carreras-Torres, R., Haycock, P. C., Relton, C. L., Martin, R. M., Smith, G. D., Kraft, P., . . . Brennan, P. (2016). The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study. SCIENTIFIC REPORTS, 6. doi:10.1038/srep31121

DOI: 10.1038/srep31121
: Journal article

Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath

Shehada, N., Cancilla, J. C., Torrecilla, J. S., Pariente, E. S., Broenstrup, G., Christiansen, S., . . . Haick, H. (2016). Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath. ACS NANO, 10(7), 7047-7057. doi:10.1021/acsnano.6b03127

DOI: 10.1021/acsnano.6b03127
: Journal article

Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci

Kachuri, L., Amos, C. I., Mckay, J. D., Johansson, M., Vineis, P., Bueno-de-Mesquita, H. B., . . . Hung, R. J. (2016). Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. CARCINOGENESIS, 37(1), 96-105. doi:10.1093/carcin/bgv165

DOI: 10.1093/carcin/bgv165
: Journal article

2015

Differentiation between genetic mutations of breast cancer by breath volatolomics

Barash, O., Zhang, W., Halpern, J. M., Hua, Q. -L., Pan, Y. -Y., Kayal, H., . . . Haick, H. (2015). Differentiation between genetic mutations of breast cancer by breath volatolomics. ONCOTARGET, 6(42), 44864-44876. doi:10.18632/oncotarget.6269

DOI: 10.18632/oncotarget.6269
: Journal article

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

Huang, R., Wei, Y., Hung, R. J., Liu, G., Su, L., Zhang, R., . . . Christiani, D. C. (2015). Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBIOMEDICINE, 2(11), 1677-1685. doi:10.1016/j.ebiom.2015.09.031

DOI: 10.1016/j.ebiom.2015.09.031
: Journal article

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N., Wang, Y., . . . Hung, R. J. (2015). Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis, 36(11), 1314-1326. doi:10.1093/carcin/bgv128

DOI: 10.1093/carcin/bgv128
: Journal article

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020

Olajide, O. O., Field, J. K., Davies, M. M. P. A., & Marcus, M. W. (2015). Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020. INTERNATIONAL JOURNAL OF ONCOLOGY, 47(2), 739-746. doi:10.3892/ijo.2015.3049

DOI: 10.3892/ijo.2015.3049
: Journal article

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020

OLAJIDE, O. O., FIELD, J. K., DAVIES, M. M. P. A., & MARCUS, M. W. (2015). Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020. International Journal of Oncology, 47(2), 739-746. doi:10.3892/ijo.2015.3049

DOI: 10.3892/ijo.2015.3049
: Journal article

Application of SureSeq solid tumour panel sequencing to a panel of FFPE samples of non small cell lung cancer from the Liverpool lung project

Hyde, R., Davies, M. P. A., Gosney, J., & Field, J. (2015). Application of SureSeq solid tumour panel sequencing to a panel of FFPE samples of non small cell lung cancer from the Liverpool lung project. In LUNG CANCER Vol. 87 (pp. S5). doi:10.1016/S0169-5002(15)50011-1

DOI: 10.1016/S0169-5002(15)50011-1
: Conference Paper

Volatile biomarkers for discrimination of lung cancer risk and mutation

Davies, M. P. A., Barash, O., Jeries, R., Peled, N., Ilouze, M., Hyde, R., . . . Field, J. (2015). Volatile biomarkers for discrimination of lung cancer risk and mutation. In LUNG CANCER Vol. 87 (pp. S4-S5). doi:10.1016/S0169-5002(15)50010-X

DOI: 10.1016/S0169-5002(15)50010-X
: Conference Paper

2014

Unique volatolomic signatures of TP53 and KRAS in lung cells

Davies, M. P. A., Barash, O., Jeries, R., Peled, N., Ilouze, M., Hyde, R., . . . Haick, H. (2014). Unique volatolomic signatures of TP53 and KRAS in lung cells. BRITISH JOURNAL OF CANCER, 111(6), 1213-1221. doi:10.1038/bjc.2014.411

DOI: 10.1038/bjc.2014.411
: Journal article

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Fernandez-Cuesta, L., Peifer, M., Lu, X., Sun, R., Ozretic, L., Seidel, D., . . . Thomas, R. K. (2014). Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids. NATURE COMMUNICATIONS, 5. doi:10.1038/ncomms4518

DOI: 10.1038/ncomms4518
: Journal article

Epigenetic biomarkers in lung cancer

Liloglou, T., Bediaga, N. G., Brown, B. R. B., Field, J. K., & Davies, M. P. A. (2014). Epigenetic biomarkers in lung cancer. CANCER LETTERS, 342(2), 200-212. doi:10.1016/j.canlet.2012.04.018

DOI: 10.1016/j.canlet.2012.04.018
: Journal article

2013

A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer

Sandoval, J., Mendez-Gonzalez, J., Nadal, E., Chen, G., Carmona, F. J., Sayols, S., . . . Esteller, M. (2013). A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer. JOURNAL OF CLINICAL ONCOLOGY, 31(32), 4140-+. doi:10.1200/JCO.2012.48.5516

DOI: 10.1200/JCO.2012.48.5516
: Journal article

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material

Bediaga, N. G., Davies, M. P. A., Acha-Sagredo, A., Hyde, R., Raji, O. Y., Page, R., . . . Liloglou, T. (2013). A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material. BRITISH JOURNAL OF CANCER, 109(9), 2404-2411. doi:10.1038/bjc.2013.623

DOI: 10.1038/bjc.2013.623
: Journal article

2012

PRE-clinical investigation of AT7519, a novel CDK inhibitor, as a potential therapeutic agent in pancreatic cancer

Thomas, A., Shaw, E., Ghaneh, P., Greenhalf, W., Davies, M., Costello, E., . . . Neoptolemos, J. P. (2012). PRE-clinical investigation of AT7519, a novel CDK inhibitor, as a potential therapeutic agent in pancreatic cancer. In Pancreatology Vol. 12 (pp. e10). Elsevier BV. doi:10.1016/j.pan.2012.03.023

DOI: 10.1016/j.pan.2012.03.023
: Conference Paper

Pre-clinical assessment of AT13387, an HSP90 inhibitor, in a pancreatic cancer xenograft model

Shaw, E., Thomas, A., Ghaneh, P., Greenhalf, W., Davies, M., Costello, E., . . . Sibson, D. R. (2012). Pre-clinical assessment of AT13387, an HSP90 inhibitor, in a pancreatic cancer xenograft model. In Pancreatology Vol. 12 (pp. e7-e8). Elsevier BV. doi:10.1016/j.pan.2012.03.020

DOI: 10.1016/j.pan.2012.03.020
: Conference Paper

MicroRNAs for early detection of lung cancer

Bediaga, N., Davies, M. P. A., Raji, O. Y., Alfirevic, A., Liloglou, T., & Field, J. K. (2012). MicroRNAs for early detection of lung cancer. CANCER RESEARCH, 72. doi:10.1158/1538-7445.AM2012-4133

DOI: 10.1158/1538-7445.AM2012-4133
: Journal article

2010

Expression of the rat calcium-binding protein p9Ka in transgenic mice.

Davies, M. P. A. (2010). Expression of the rat calcium-binding protein p9Ka in transgenic mice..

: Thesis / Dissertation

Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression

Barraclough, D. L., Sewart, S., Rudland, P. S., Shoker, B. S., Sibson, D. R., Barraclough, R., & Davies, M. P. A. (2010). Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression. Analytical Cellular Pathology, 32(1-2), 87-99. doi:10.1155/2010/582416

DOI: 10.1155/2010/582416
: Journal article

2008

Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer

Davies, M. P. A., Barraclough, D. L., Stewart, C., Joyce, K. A., Eccles, R. M., Barraclough, R., . . . Sibson, D. R. (2008). Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer. INTERNATIONAL JOURNAL OF CANCER, 123(1), 85-88. doi:10.1002/ijc.23479

DOI: 10.1002/ijc.23479
: Journal article

2007

Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study

Vinayagam, R., Sibson, D. R., Holcombe, C., Aachi, V., & Davies, M. P. (2007). Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study. BMC CANCER, 7. doi:10.1186/1471-2407-7-131

DOI: 10.1186/1471-2407-7-131
: Journal article

2006

Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients

Innes, H. E., Liu, D., Barraclough, R., Davies, M. P. A., O'Neill, P. A., Platt-Higgins, A., . . . Rudland, P. S. (2006). Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. BRITISH JOURNAL OF CANCER, 94(7), 1057-1065. doi:10.1038/sj.bjc.6603065

DOI: 10.1038/sj.bjc.6603065
: Journal article

2005

Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas

Davies, M. P. A., O'Neill, P. A., Innes, H., & Sibson, D. R. (2005). Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas. BREAST CANCER RESEARCH, 7(1), R113-R118. doi:10.1186/bcr965

DOI: 10.1186/bcr965
: Journal article

2004

Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer

Davies, M. P. A., O'Neill, P. A., Innes, H., Sibson, D. R., Prime, W., Holcombe, C., & Foster, C. S. (2004). Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer. JOURNAL OF MOLECULAR ENDOCRINOLOGY, 33(3), 773-782. doi:10.1677/jme.1.01574

DOI: 10.1677/jme.1.01574
: Journal article

Wild-type oestrogen receptor beta (ERb1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers

O'Neill, P. A., Davies, M. P. A., Shaaban, A. M., Innes, H., Torevell, A., Sibson, D. R., & Foster, C. S. (2004). Wild-type oestrogen receptor beta (ERb1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers. BRITISH JOURNAL OF CANCER, 91(9), 1694-1702. doi:10.1038/sj.bjc.6602183

DOI: 10.1038/sj.bjc.6602183
: Journal article

Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27

O'Neill, P. A., Shaaban, A. M., West, C. R., Dodson, A., Jarvis, C., Moore, P., . . . Foster, C. S. (2004). Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27. BRITISH JOURNAL OF CANCER, 90(1), 182-188. doi:10.1038/sj.bjc.6601449

DOI: 10.1038/sj.bjc.6601449
: Journal article

2003

Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia

Shaaban, A. M., O'Neill, P. A., Davies, M. P. A., Sibson, R., West, C. R., Smith, P. H., & Foster, C. S. (2003). Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 27(12), 1502-1512. doi:10.1097/00000478-200312000-00002

DOI: 10.1097/00000478-200312000-00002
: Journal article

Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer

Simpson, P. T., Shoker, B. S., Barraclough, R., Halliwell, N., Rudland, P. S., Sibson, D. R., & Davies, M. P. A. (2003). Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 84(4), 173-183. doi:10.1046/j.1365-2613.2003.00350.x

DOI: 10.1046/j.1365-2613.2003.00350.x
: Journal article

2002

Molecular and genetic abnormalities in radial scar

Iqbal, M., Shoker, B. S., Foster, C. S., Jarvis, C., Sibson, D. R., & Davies, M. P. A. (2002). Molecular and genetic abnormalities in radial scar. HUMAN PATHOLOGY, 33(7), 715-722. doi:10.1053/hupa.2002.125375

DOI: 10.1053/hupa.2002.125375
: Journal article

2001

Hypersensitive K303R oestrogen receptor variant not found in ductal carcinoma in situ

Davies, M. P. A., Iqbal, M., Shoker, B. S., & Sibson, D. R. (2001). Hypersensitive K303R oestrogen receptor variant not found in ductal carcinoma in situ. In European Journal of Cancer Vol. 37 (pp. 29). Elsevier BV. doi:10.1016/s0959-8049(01)80116-7

DOI: 10.1016/s0959-8049(01)80116-7
: Conference Paper

Immunodetectable cyclin D1 is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions

Shoker, B. S., Jarvis, C., Davies, M. P. A., Iqbal, M., Sibson, D. R., & Sloane, J. P. (2001). Immunodetectable cyclin D1 is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions. BRITISH JOURNAL OF CANCER, 84(8), 1064-1069. doi:10.1054/bjoc.2001.1705

DOI: 10.1054/bjoc.2001.1705
: Journal article

Characterisation of molecular alterations in microdissected archival gliomas

Walker, C., Joyce, K. A., Thompson-Hehir, J., Davies, M. P. A., Gibbs, F. E. M., Halliwell, N., . . . Rossi, M. L. (2001). Characterisation of molecular alterations in microdissected archival gliomas. ACTA NEUROPATHOLOGICA, 101(4), 321-333. Retrieved from https://www.webofscience.com/

: Journal article

Subgroups of non-atypical hyperplasia of breast defined by proliferation of oestrogen receptor-positive cells

Iqbal, M., Davies, M. P. A., Shoker, B. S., Jarvis, C., Sibson, D. R., & Sloane, J. P. (2001). Subgroups of non-atypical hyperplasia of breast defined by proliferation of oestrogen receptor-positive cells. JOURNAL OF PATHOLOGY, 193(3), 333-338. doi:3.0.CO;2-#">10.1002/1096-9896(2000)9999:9999<::AID-PATH801>3.0.CO;2-#

DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH801>3.0.CO;2-#
: Journal article

2000

Abnormal regulation of the oestrogen receptor in benign breast lesions

Shoker, B. S., Jarvis, C., Clarke, R. B., Anderson, E., Munro, C., Davies, M. P. A., . . . Sloane, J. P. (2000). Abnormal regulation of the oestrogen receptor in benign breast lesions. JOURNAL OF CLINICAL PATHOLOGY, 53(10), 778-783. doi:10.1136/jcp.53.10.778

DOI: 10.1136/jcp.53.10.778
: Journal article

Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors

Thompson-Hehir, J., Davies, M. P. A., Green, J. A., Halliwell, N., Joyce, K. A., Salisbury, J., . . . Walker, C. (2000). Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors. DIAGNOSTIC MOLECULAR PATHOLOGY, 9(2), 110-119. doi:10.1097/00019606-200006000-00007

DOI: 10.1097/00019606-200006000-00007
: Journal article

1999

Estrogen receptor-positive proliferating cells in the normal and precancerous breast

Shoker, B. S., Jarvis, C., Clarke, R. B., Anderson, E., Hewlett, J., Davies, M. P. A., . . . Sloane, J. P. (1999). Estrogen receptor-positive proliferating cells in the normal and precancerous breast. AMERICAN JOURNAL OF PATHOLOGY, 155(6), 1811-1815. doi:10.1016/S0002-9440(10)65498-3

DOI: 10.1016/S0002-9440(10)65498-3
: Journal article

Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas

Davies, M. P. A., Gibbs, F. E. M., Halliwell, N., Joyce, K. A., Roebuck, M. M., Rossi, M. L., . . . Walker, C. (1999). Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas. BRITISH JOURNAL OF CANCER, 79(9-10), 1542-1548. doi:10.1038/sj.bjc.6690246

DOI: 10.1038/sj.bjc.6690246
: Journal article

1998

Use of DNA transfer in the induction of metastasis in experimental mammary systems

Barraclough, R., Chen, H. J., Davies, B. R., Davies, M. P. A., Ke, Y. Q., Lloyd, B. H., . . . Rudland, P. S. (1998). Use of DNA transfer in the induction of metastasis in experimental mammary systems. MAMMARY DEVELOPMENT IN CANCER, (63), 273-294. Retrieved from https://www.webofscience.com/

: Journal article

1997

Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor

Chen, D. S., Davies, M. P. A., Rudland, P. S., & Barraclough, R. (1997). Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor. JOURNAL OF BIOLOGICAL CHEMISTRY, 272(32), 20283-20290. doi:10.1074/jbc.272.32.20283

DOI: 10.1074/jbc.272.32.20283
: Journal article

Elevated expression of calcium-binding protein p9Ka is associated with increasing malignant characteristics of rat prostate carcinoma cells

Ke, Y. Q., Jing, C., Barraclough, R., Smith, P., Davies, M. P. A., & Foster, C. S. (1997). Elevated expression of calcium-binding protein p9Ka is associated with increasing malignant characteristics of rat prostate carcinoma cells. INTERNATIONAL JOURNAL OF CANCER, 71(5), 832-837. doi:3.0.CO;2-8">10.1002/(SICI)1097-0215(19970529)71:5<832::AID-IJC22>3.0.CO;2-8

DOI: 10.1002/(SICI)1097-0215(19970529)71:5<832::AID-IJC22>3.0.CO;2-8
: Journal article

1996

Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours

Davies, M. P. A., Rudland, P. S., Robertson, L., Parry, E. W., Jolicoeur, P., & Barraclough, R. (1996). Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. ONCOGENE, 13(8), 1631-1637. Retrieved from https://www.webofscience.com/

: Journal article

Growth & mammary abnormalities in mice containing an altered calcium-binding protein transgene

Davies, M. P. A., Harris, S., Rudland, P. S., & Barraclough, R. (1996). Growth & mammary abnormalities in mice containing an altered calcium-binding protein transgene. BIOCHEMICAL SOCIETY TRANSACTIONS, 24(3), S356. doi:10.1042/bst024356s

DOI: 10.1042/bst024356s
: Journal article

1995

EXPRESSION OF THE RAT, S-100-RELATED, CALCIUM-BINDING PROTEIN GENE, P9KA, IN TRANSGENIC MICE DEMONSTRATES DIFFERENT PATTERNS OF EXPRESSION BETWEEN THESE 2 SPECIES

DAVIES, M., HARRIS, S., RUDLAND, P., & BARRACLOUGH, R. (1995). EXPRESSION OF THE RAT, S-100-RELATED, CALCIUM-BINDING PROTEIN GENE, P9KA, IN TRANSGENIC MICE DEMONSTRATES DIFFERENT PATTERNS OF EXPRESSION BETWEEN THESE 2 SPECIES. DNA AND CELL BIOLOGY, 14(10), 825-832. doi:10.1089/dna.1995.14.825

DOI: 10.1089/dna.1995.14.825
: Journal article

1993

Induction of the metastatic phenotype in rat mammary benign tumour cells by the gene for p9Ka a novel calcium-binding protein

Barraclough, R., Davies, B. R., Davies, M. P. A., Gibbs, F. E. M., & Rudland, P. S. (1993). Induction of the metastatic phenotype in rat mammary benign tumour cells by the gene for p9Ka a novel calcium-binding protein. In The Breast Vol. 2 (pp. 191). Elsevier BV. doi:10.1016/0960-9776(93)90090-3

DOI: 10.1016/0960-9776(93)90090-3
: Conference Paper

INDUCTION OF THE METASTATIC PHENOTYPE BY TRANSFECTION OF A BENIGN RAT MAMMARY EPITHELIAL-CELL LINE WITH THE GENE FOR P9KA, A RAT CALCIUM-BINDING PROTEIN, BUT NOT WITH THE ONCOGENE EJ-RAS-1

DAVIES, B. R., DAVIES, M. P. A., GIBBS, F. E. M., BARRACLOUGH, R., & RUDLAND, P. S. (1993). INDUCTION OF THE METASTATIC PHENOTYPE BY TRANSFECTION OF A BENIGN RAT MAMMARY EPITHELIAL-CELL LINE WITH THE GENE FOR P9KA, A RAT CALCIUM-BINDING PROTEIN, BUT NOT WITH THE ONCOGENE EJ-RAS-1. ONCOGENE, 8(4), 999-1008. Retrieved from https://www.webofscience.com/

: Journal article

PRODUCTION OF THE METASTATIC PHENOTYPE BY DNA TRANSFECTION IN A RAT MAMMARY MODEL

DAVIES, B. R., BARRACLOUGH, R., DAVIES, M. P. A., & RUDLAND, P. S. (1993). PRODUCTION OF THE METASTATIC PHENOTYPE BY DNA TRANSFECTION IN A RAT MAMMARY MODEL. CELL BIOLOGY INTERNATIONAL, 17(9), 871-879. doi:10.1006/cbir.1993.1150

DOI: 10.1006/cbir.1993.1150
: Journal article

1990

USE OF FLUO-3 TO MEASURE CYTOSOLIC CA-2+ IN PLATELETS AND NEUTROPHILS - LOADING CELLS WITH THE DYE, CALIBRATION OF TRACES, MEASUREMENTS IN THE PRESENCE OF PLASMA, AND BUFFERING OF CYTOSOLIC CA-2+

MERRITT, J. E., MCCARTHY, S. A., DAVIES, M. P. A., & MOORES, K. E. (1990). USE OF FLUO-3 TO MEASURE CYTOSOLIC CA-2+ IN PLATELETS AND NEUTROPHILS - LOADING CELLS WITH THE DYE, CALIBRATION OF TRACES, MEASUREMENTS IN THE PRESENCE OF PLASMA, AND BUFFERING OF CYTOSOLIC CA-2+. BIOCHEMICAL JOURNAL, 269(2), 513-519. doi:10.1042/bj2690513

DOI: 10.1042/bj2690513
: Journal article

A ROLE FOR CALCIUM AND PROTEIN KINASE-C IN AGONIST-STIMULATED ADHESION OF HUMAN NEUTROPHILS

DAVIES, M. P. A., HALLAM, T. J., & MERRITT, J. E. (1990). A ROLE FOR CALCIUM AND PROTEIN KINASE-C IN AGONIST-STIMULATED ADHESION OF HUMAN NEUTROPHILS. BIOCHEMICAL JOURNAL, 267(1), 13-16. doi:10.1042/bj2670013

DOI: 10.1042/bj2670013
: Journal article

1989

A ROLE FOR CYTOPLASMIC CALCIUM IN THE STIMULATION OF NEUTROPHIL ADHESION

DAVIES, M. P. A., MOORES, K. E., & MERRITT, J. E. (1989). A ROLE FOR CYTOPLASMIC CALCIUM IN THE STIMULATION OF NEUTROPHIL ADHESION. BIOCHEMICAL SOCIETY TRANSACTIONS, 17(1), 123. doi:10.1042/bst0170123

DOI: 10.1042/bst0170123
: Journal article

Publications

Selected publications

2024

Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers.

EP.13D.12 International Consortium Real-World Outcomes in Extensive Disease Small Cell Lung Cancer Compared to IMPOWER133 And CASPIAN

MA17.03 30 Years of International Real World Outcomes in Patients with Limited Disease Small Cell Lung Cancer

Impact of single round of low dose CT lung cancer screening on cause of mortality in different socio-economic groups: a post-hoc analysis of long-term follow-up of the UKLS trial.

2023

Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications

On the Non-Linearity of Radon-Induced Lung Cancer

2022

On the non-linearity of radon-induced lung cancer

On the non-linearity of radon-induced lung cancer

Circulating Proteome for Pulmonary Nodule Malignancy

EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups

On the non-linearity of radon-induced lung cancer

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program

Impact of risk-based low dose CT screening on different socio-economic groups

Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups

2021

OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis

Gene-gene Interaction of AhR with and within the Wnt Cascade Affects Susceptibility to Lung Cancer

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

Gene-gene Interaction of AhR With and Within the Wnt Cascade Affects Susceptibility to Lung Cancer

FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC

FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People

2020

2019

Implementation Planning of Lung Cancer Screening in China

Pathogenic Germline Rare Variants and Risk of Lung Cancer

Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Implementation planning for lung cancer screening in China

Lung cancer screening programmes: landscape in China

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases

2018

2017

Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer

2016

2015

Differentiation between genetic mutations of breast cancer by breath volatolomics

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020

Application of SureSeq solid tumour panel sequencing to a panel of FFPE samples of non small cell lung cancer from the Liverpool lung project

Volatile biomarkers for discrimination of lung cancer risk and mutation

2014

Unique volatolomic signatures of TP53 and KRAS in lung cells

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Epigenetic biomarkers in lung cancer

2013

A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material

2012

PRE-clinical investigation of AT7519, a novel CDK inhibitor, as a potential therapeutic agent in pancreatic cancer

Pre-clinical assessment of AT13387, an HSP90 inhibitor, in a pancreatic cancer xenograft model

MicroRNAs for early detection of lung cancer

2010

Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression

2008

Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer

2007

2006

Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients

2005

Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas

2004

Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer

Wild-type oestrogen receptor beta (ERb1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers

Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27

2003

Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia

Examination of tumour histopathology and gene expression in a <i>neu</i>/<i>S100A4</i> transgenic model of metastatic breast cancer

2002

Molecular and genetic abnormalities in radial scar

2001

Hypersensitive K303R oestrogen receptor variant not found in ductal carcinoma in situ

Immunodetectable cyclin D<sub>1</sub> is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions