Publications
Selected publications
- Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor (Journal article - 2021)
- Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. (Journal article - 2017)
- Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis (Journal article - 2019)
- Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury (Journal article - 2015)
- Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B (Journal article - 2014)
- Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein (vol 79, pg 887, 2013) (Journal article - 2013)
- Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons (Journal article - 2012)
- Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation (Journal article - 2011)
- Multimodal imaging of synaptic vesicles with a single probe (Journal article - 2022)
2023
Impact of various buffers and weak bases on lysosomal and intracellular pH: Implications for infectivity of SARS-CoV-2
Kraut, J. A., Cheetham-Wilkinson, I. J., Swan, L. E., Stagi, M., & Kurtz, I. (2023). Impact of various buffers and weak bases on lysosomal and intracellular pH: Implications for infectivity of SARS-CoV-2. FASEB BIOADVANCES, 5(4), 149-155. doi:10.1096/fba.2022-00062
In silico modeling human VPS13 proteins associated with donor and target membranes suggests lipid transfer mechanisms
Dall'Armellina, F., Stagi, M., & Swan, L. E. (2023). In silico modeling human VPS13 proteins associated with donor and target membranes suggests lipid transfer mechanisms. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 91(4), 439-455. doi:10.1002/prot.26446
2022
Multimodal imaging of synaptic vesicles with a single probe
An, S. J., Stagi, M., Gould, T. J., Wu, Y., Mlodzianoski, M., Rivera-Molina, F., . . . Zenisek, D. (2022). Multimodal imaging of synaptic vesicles with a single probe. Cell Reports Methods, 2(4), 100199. doi:10.1016/j.crmeth.2022.100199
Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses
Papoutsopoulou, S., Morris, L., Bayliff, A., Mair, T., England, H., Stagi, M., . . . Campbell, B. J. (2022). Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses. BIOMEDICINES, 10(4). doi:10.3390/biomedicines10040757
2021
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
Ponsford, A. H., Ryan, T. A., Raimondi, A., Cocucci, E., Wycislo, S. A., Fröhlich, F., . . . Stagi, M. (n.d.). Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor. Autophagy, 1-19. doi:10.1080/15548627.2020.1771858
How mTORC1 makes sense of nutrients
Luciani, A., & Stagi, M. (2021). How mTORC1 makes sense of nutrients. KIDNEY INTERNATIONAL, 99(2), 295-298. doi:10.1016/j.kint.2020.07.052
2019
Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.
Luscher, A., Fröhlich, F., Barisch, C., Littlewood, C., Metcalfe, J., Leuba, F., . . . Swan, L. E. (2019). Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.. Molecular biology of the cell, 30(17), 2268-2282. doi:10.1091/mbc.E18-08-0510
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis
Fernandez-Mosquera, L., Yambire, K. F., Renata, C., Pereyra, L., Pabis, K., Ponsford, A. H., . . . Raimundo, N. (2019). Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis. Autophagy, 15(9), 1572-1591. doi:10.1080/15548627.2019.1586256
Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists (vol 26, pg 145, 2019)
Gunther, E. C., Smith, L. M., Kostylev, M. A., Cox, T. O., Kaufman, A. C., Lee, S., . . . Strittmatter, S. M. (2019). Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists (vol 26, pg 145, 2019). CELL REPORTS, 26(5), 1368. doi:10.1016/j.celrep.2019.01.064
2017
Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice.
Zoe Klein., Hideyuki Takahashi., Mengxiao Ma., Massimiliano Stagi., Melissa Zhou., TuKiet Lam., & Stephen M. Strittmatter. (2017). Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice.. Neuron, 95(2), 281-296. doi:10.1016/j.neuron.2017.06.026
Co-culture Synaptogenic Assay: A New Look at Fluorescence Reporters and Technological Devices
de Arce, K. P., & Stagi, M. (2017). Co-culture Synaptogenic Assay: A New Look at Fluorescence Reporters and Technological Devices. In SYNAPSE DEVELOPMENT (Vol. 1538, pp. 13-27). doi:10.1007/978-1-4939-6688-2_2
2015
Low cost production of 3D-printed devices and electrostimulation chambers for the culture of primary neurons
Wardyn, J., Sanderson, C., Swan, L., & Stagi, M. (2015). Low cost production of 3D-printed devices and electrostimulation chambers for the culture of primary neurons. Journal of Neuroscience Methods, 251, 17-23. doi:10.1016/j.jneumeth.2015.05.001
Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury
Zou, Y., Stagi, M., Wang, X., Yigitkanli, K., Siegel, C. S., Nakatsu, F., . . . Strittmatter, S. M. (2015). Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury. The Journal of Neuroscience, 35(29), 10429-10439. doi:10.1523/JNEUROSCI.1718-15.2015
2014
Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B
Stagi, M., Klein, Z. A., Gould, T. J., Bewersdorf, J., & Strittmatter, S. M. (2016). Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B. Molecular and Cellular Neuroscience, 61, 226-240. doi:10.1016/j.mcn.2014.07.006
2013
Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein (vol 79, pg 887, 2013)
Um, J. W., Kaufman, A. C., Kostylev, M., Heiss, J. K., Stagi, M., Takahashi, H., . . . Strittmatter, S. M. (2013). Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein (vol 79, pg 887, 2013). NEURON, 80(2), 531. doi:10.1016/j.neuron.2013.10.001
Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
Um, J. W., Kaufman, A. C., Kostylev, M., Heiss, J. K., Stagi, M., Takahashi, H., . . . Strittmatter, S. M. (2013). Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein. NEURON, 79(5), 887-902. doi:10.1016/j.neuron.2013.06.036
2012
Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
Um, J. W., Nygaard, H. B., Heiss, J. K., Kostylev, M. A., Stagi, M., Vortmeyer, A., . . . Strittmatter, S. M. (2012). Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. NATURE NEUROSCIENCE, 15(9), 1227-1U85. doi:10.1038/nn.3178
2011
Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation
Fogel, A. I., Stagi, M., de Arce, K. P., & Biederer, T. (2011). Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO JOURNAL, 30(23), 4728-4738. doi:10.1038/emboj.2011.336
2010
SynCAM 1 participates in axo-dendritic contact assembly and shapes neuronal growth cones
Stagi, M., Fogel, A. I., & Biederer, T. (2010). SynCAM 1 participates in axo-dendritic contact assembly and shapes neuronal growth cones. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(16), 7568-7573. doi:10.1073/pnas.0911798107
2008
SynCAM complexes encode synaptic adhesion to organize nascent synapses
Fogel, A. I., Stagi, M., Krupp, A., Stein, V., & Biederer, T. (2008). SynCAM complexes encode synaptic adhesion to organize nascent synapses. In INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE Vol. 26 (pp. 840). doi:10.1016/j.ijdevneu.2008.09.045
Signaling by synaptogenic molecules
Biederer, T., & Stagi, M. (2008). Signaling by synaptogenic molecules. CURRENT OPINION IN NEUROBIOLOGY, 18(3), 261-269. doi:10.1016/j.conb.2008.07.014
2007
SynCAMs organize synapses through heterophilic adhesion
Fogel, A. I., Akins, M. R., Krupp, A. J., Stagi, M., Stein, V., & Biederer, T. (2007). SynCAMs organize synapses through heterophilic adhesion. JOURNAL OF NEUROSCIENCE, 27(46), 12516-12530. doi:10.1523/JNEUROSCI.2739-07.2007
TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis
Takahashi, K., Prinz, M., Stagi, M., Chechneva, O., & Neumann, H. (2007). TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis. PLOS MEDICINE, 4(4), 675-689. doi:10.1371/journal.pmed.0040124
Tissue debris clearance by TREM2-transduced myeloid precursors in experimental autoimmune encephalomyelitis
Takahashi, K., Prinz, M., Stagi, M., Chechneva, O., & Neumann, H. (2007). Tissue debris clearance by TREM2-transduced myeloid precursors in experimental autoimmune encephalomyelitis. In EUROPEAN JOURNAL OF NEUROLOGY Vol. 14 (pp. 130). Retrieved from https://www.webofscience.com/
2006
Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway
Stagi, M., Gorlovoy, P., Larionov, S., Takahashi, K., & Neumann, H. (2006). Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway. FASEB JOURNAL, 20(14), 2573-+. doi:10.1096/fj.06-6679fje
2005
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide
Liu, Y., Walter, S., Stagi, M., Cherny, D., Letiembre, M., Schulz-Schaeffer, W., . . . Fassbender, K. (2005). LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide. BRAIN, 128, 1778-1789. doi:10.1093/brain/awh531
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide
Stagi, M., Dittrich, P. S., Frank, N., Iliev, A. I., Schwille, P., & Neumann, H. (2005). Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide. JOURNAL OF NEUROSCIENCE, 25(2), 352-362. doi:10.1523/JNEUROSCI.3887-04.2005
2004
Effect of inflammatory mediators on axonal transport of synaptic vesicle proteins
Stagi, M., Frank, N., & Neumann, H. (2004). Effect of inflammatory mediators on axonal transport of synaptic vesicle proteins. In JOURNAL OF NEUROIMMUNOLOGY Vol. 154 (pp. 168). Retrieved from https://www.webofscience.com/
2003
Effect of inflammatory mediators on axonal transport of synaptic vesicle proteins
Stagi, M., Frank, N., & Neumann, H. (2003). Effect of inflammatory mediators on axonal transport of synaptic vesicle proteins. In GLIA (pp. 43). Retrieved from https://www.webofscience.com/