Publications
2023
Disruption of Dcp1 leads to a Dcp2-dependent aberrant ribosome profiles in <i>Aspergillus nidulans</i>
Bharudin, I., Caddick, M. X., Connell, S. R., Lamaudiere, M. T. F., & Morozov, I. Y. (2023). Disruption of Dcp1 leads to a Dcp2-dependent aberrant ribosome profiles in <i>Aspergillus nidulans</i>. MOLECULAR MICROBIOLOGY. doi:10.1111/mmi.15059
2022
VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center
Amos, B., Aurrecoechea, C., Barba, M., Barreto, A., Basenko, E. Y., Bazant, W., . . . Zheng, J. (2022). VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center. NUCLEIC ACIDS RESEARCH, 50(D1), D898-D911. doi:10.1093/nar/gkab929
2021
Histone mRNA is subject to 3′ uridylation and re-adenylation in <i>Aspergillus nidulans</i>
Mossanen-Parsi, A., Parisi, D., Browne-Marke, N., Bharudin, I., Connell, S. R., Mayans, O., . . . Caddick, M. X. (2021). Histone mRNA is subject to 3′ uridylation and re-adenylation in <i>Aspergillus nidulans</i>. MOLECULAR MICROBIOLOGY, 115(2), 238-254. doi:10.1111/mmi.14613
2020
Growing a circular economy with fungal biotechnology: a white paper.
Meyer, V., Basenko, E. Y., Benz, J. P., Braus, G. H., Caddick, M. X., Csukai, M., . . . Wösten, H. A. B. (2020). Growing a circular economy with fungal biotechnology: a white paper.. Fungal biology and biotechnology, 7, 5. doi:10.1186/s40694-020-00095-z
2019
High-Quality Draft Genome Sequence and Annotation of the Basidiomycete Yeast <i>Sporisorium graminicola</i> CBS10092, a Producer of Mannosylerythritol Lipids
Solano-Gonzalez, S., Darby, A. C., Cossar, D., & Caddick, M. X. (2019). High-Quality Draft Genome Sequence and Annotation of the Basidiomycete Yeast <i>Sporisorium graminicola</i> CBS10092, a Producer of Mannosylerythritol Lipids. MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 8(42). doi:10.1128/MRA.00479-19
Building a global alliance of biofoundries (vol 10, 2040, 2019)
Hillson, N., Caddick, M., Cai, Y., Carrasco, J. A., Chang, M. W., Curach, N. C., . . . Freemont, P. S. (2019). Building a global alliance of biofoundries (vol 10, 2040, 2019). NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-10862-1
Similarity Regression predicts evolution of transcription factor sequence specificity
Lambert, S. A., Yang, A., Sasse, A., Cowley, G., Albu, M., Caddick, M. X., . . . Hughes, T. R. (2019). Similarity Regression predicts evolution of transcription factor sequence specificity. Nature Genetics, 51, 981-989. doi:10.1038/s41588-019-0411-1
Building a global alliance of biofoundries
Hillson, N., Caddick, M., Cai, Y., Carrasco, J. A., Chang, M. W., Curach, N. C., . . . Freemont, P. S. (2019). Building a global alliance of biofoundries. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-10079-2
The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans
Caddick, M. X. (2019). The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans. FEMS Microbiology Letters. doi:10.1093/femsle/fnz066
The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans.
Chudzicka-Ormaniec, P., Macios, M., Koper, M., Weedall, G., Caddick, M., Weglenski, P., & Dzikowska, A. (2019). The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans.. FEMS Microbiology Letters, 366(6). doi:10.1093/femsle/fnz066
2017
The Role of eIF6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-Expression Networks
Clarke, K., Ricciardi, S., Pearson, T., Bharudin, I., Davidsen, P. K., Bonomo, M., . . . Falciani, F. (2017). The Role of eIF6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-Expression Networks. Cell Reports, 21(6), 1507-1520. doi:10.1016/j.celrep.2017.10.040
Leaf LIMS: A Flexible Laboratory Information Management System with a Synthetic Biology Focus.
Craig, T., Holland, R., D'Amore, R., Johnson, J. R., McCue, H. V., West, A., . . . Caddick, M. X. (2017). Leaf LIMS: A Flexible Laboratory Information Management System with a Synthetic Biology Focus.. ACS synthetic biology, 6(12), 2273-2280. doi:10.1021/acssynbio.7b00212
2016
Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.
Meyer, V., Andersen, M. R., Brakhage, A. A., Braus, G. H., Caddick, M. X., Cairns, T. C., . . . Head, R. M. (2016). Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.. Fungal biology and biotechnology, 3, 6. doi:10.1186/s40694-016-0024-8
2015
3' end mRNA tagging: A novel quality control mechanism that coordinates mRNA translation and degradation
Morozov, I., & Caddick, M. X. (2015). 3' end mRNA tagging: A novel quality control mechanism that coordinates mRNA translation and degradation. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 36, S29. Retrieved from https://www.webofscience.com/
2013
Transcriptome analysis of the filamentous fungus Aspergillus nidulans directed to the global identification of promoters.
Sibthorp, C., Wu, H., Cowley, G., Wong, P. W. H., Palaima, P., Morozov, I. Y., . . . Caddick, M. X. (2013). Transcriptome analysis of the filamentous fungus Aspergillus nidulans directed to the global identification of promoters.. BMC genomics, 14, 847. doi:10.1186/1471-2164-14-847
RrmA regulates the stability of specific transcripts in response to both nitrogen source and oxidative stress.
Krol, K., Morozov, I. Y., Jones, M. G., Wyszomirski, T., Weglenski, P., Dzikowska, A., & Caddick, M. X. (2013). RrmA regulates the stability of specific transcripts in response to both nitrogen source and oxidative stress.. Molecular microbiology, 89(5), 975-988. doi:10.1111/mmi.12324
Finding DNA Regulatory Motifs with Position-dependent Models
Wu, H., Wong, P. W. H., Caddick, M. X., & Sibthorp, C. (2013). Finding DNA Regulatory Motifs with Position-dependent Models. Journal of Medical and Bioengineering, 2(2), 103-109. doi:10.12720/jomb.2.2.103-109
2012
mRNA 3′ Tagging Is Induced by Nonsense-Mediated Decay and Promotes Ribosome Dissociation
Morozov, I. Y., Jones, M. G., Gould, P. D., Crome, V., Wilson, J. B., Hall, A. J. W., . . . Caddick, M. X. (2012). mRNA 3′ Tagging Is Induced by Nonsense-Mediated Decay and Promotes Ribosome Dissociation. MOLECULAR AND CELLULAR BIOLOGY, 32(13), 2585-2595. doi:10.1128/MCB.00316-12
The GATA factors AREA and AREB together with the co-repressor NMRA, negatively regulate arginine catabolism in Aspergillus nidulans in response to nitrogen and carbon source.
Macios, M., Caddick, M. X., Weglenski, P., Scazzocchio, C., & Dzikowska, A. (2012). The GATA factors AREA and AREB together with the co-repressor NMRA, negatively regulate arginine catabolism in Aspergillus nidulans in response to nitrogen and carbon source.. Fungal genetics and biology : FG & B, 49(3), 189-198. doi:10.1016/j.fgb.2012.01.004
Cytoplasmic mRNA 3' tagging in eukaryotes: Does it spell the end?
Morozov, I. Y., & Caddick, M. (2012). Cytoplasmic mRNA 3' tagging in eukaryotes: Does it spell the end?. Unknown Journal, 1.
2011
Title: Characterisation of AnBEST1, a functional anion channel in the plasma membrane of the filamentous fungus, Aspergillus nidulans
Roberts, S. K., Milnes, J., & Caddick, M. (2011). Title: Characterisation of AnBEST1, a functional anion channel in the plasma membrane of the filamentous fungus, Aspergillus nidulans. FUNGAL GENETICS AND BIOLOGY, 48(9), 928-938.
2010
The bZIP Transcription Factor MeaB Mediates Nitrogen Metabolite Repression at Specific Loci
Wagner, D., Schmeinck, A., Mos, M., Morozov, I. Y., Caddick, M. X., & Tudzynski, B. (2010). The bZIP Transcription Factor MeaB Mediates Nitrogen Metabolite Repression at Specific Loci. Eukaryotic Cell, 9(10), 1588-1601. doi:10.1128/ec.00146-10
The bZIP transcription factor MeaB mediates nitrogen metabolite repression at specific loci.
Wagner, D., Schmeinck, A., Mos, M., Morozov, I. Y., Caddick, M. X., & Tudzynski, B. (2010). The bZIP transcription factor MeaB mediates nitrogen metabolite repression at specific loci.. Eukaryotic cell, 9(10), 1588-1601. doi:10.1128/ec.00146-10
Blue Skies, Green Fields
Caddick, M. X. (2010). Blue Skies, Green Fields. Public Service Review: UK Science and Technology, 1, 72.
CUCU Modification of mRNA Promotes Decapping and Transcript Degradation in <i>Aspergillus nidulans</i>
Morozov, I. Y., Jones, M. G., Razak, A. A., Rigden, D. J., & Caddick, M. X. (2010). CUCU Modification of mRNA Promotes Decapping and Transcript Degradation in <i>Aspergillus nidulans</i>. MOLECULAR AND CELLULAR BIOLOGY, 30(2), 460-469. doi:10.1128/MCB.00997-09
Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co-ordination of transcript deadenylation, decapping and P-body formation in <i>Aspergillus nidulans</i>
Morozov, I. Y., Jones, M. G., Spiller, D. G., Rigden, D. J., Dattenboeck, C., Novotny, R., . . . Caddick, M. X. (2010). Distinct roles for Caf1, Ccr4, Edc3 and CutA in the co-ordination of transcript deadenylation, decapping and P-body formation in <i>Aspergillus nidulans</i>. MOLECULAR MICROBIOLOGY, 76(2), 503-516. doi:10.1111/j.1365-2958.2010.07118.x
mRNA stability and its role in biomedical sciences
Morozov, I., & Caddick, M. X. (2010). mRNA stability and its role in biomedical sciences. Int J Mol Med, 26, s24.
2007
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88.
Pel, H. J., de Winde, J. H., Archer, D. B., Dyer, P. S., Hofmann, G., Schaap, P. J., . . . Stam, H. (2007). Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88.. Nature biotechnology, 25(2), 221-231. doi:10.1038/nbt1282
Applications of Inducible Transcription in Plant Research and Biotechnology
Tomsett, B., Tregova, A., & Caddick, M. (n.d.). Applications of Inducible Transcription in Plant Research and Biotechnology. In Unknown Book (pp. 309-328). Wiley. doi:10.1002/9781119312994.apr0308
Gene regulation
Caddick, M. X., & Dobson, C. (2007). Gene regulation. In G. Goldman, & S. Osmani (Eds.), The Aspergilli: Genomics, Medical Applications, Biotechnology, and Research Methods. (pp. 153-161). New York: CRC Press.
2006
Nonsense-mediated mRNA decay mutation in Aspergillus nidulans.
Morozov, I. Y., Negrete-Urtasun, S., Tilburn, J., Jansen, C. A., Caddick, M. X., & Arst, H. N. (2006). Nonsense-mediated mRNA decay mutation in Aspergillus nidulans.. Eukaryotic cell, 5(11), 1838-1846. doi:10.1128/ec.00220-06
Opposing signals differentially regulate transcript stability in Aspergillus nidulans.
Caddick, M. X., Jones, M. G., van Tonder, J. M., Le Cordier, H., Narendja, F., Strauss, J., & Morozov, I. Y. (2006). Opposing signals differentially regulate transcript stability in Aspergillus nidulans.. Molecular microbiology, 62(2), 509-519. doi:10.1111/j.1365-2958.2006.05383.x
Gene regulation in Aspergillus: From genetics to genomics.
Caddick, M. X., Dobson, C., Morozov, I. Y., & Jones, M. G. (2006). Gene regulation in Aspergillus: From genetics to genomics.. Medical mycology, 44(Supplement_1), S13-S16. doi:10.1080/13693780600835781
The GATA factor AreA regulates localization and in vivo binding site occupancy of the nitrate activator NirA.
Berger, H., Pachlinger, R., Morozov, I., Goller, S., Narendja, F., Caddick, M., & Strauss, J. (2006). The GATA factor AreA regulates localization and in vivo binding site occupancy of the nitrate activator NirA.. Molecular microbiology, 59(2), 433-446. doi:10.1111/j.1365-2958.2005.04957.x
2005
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.
Galagan, J. E., Calvo, S. E., Cuomo, C., Ma, L. -J., Wortman, J. R., Batzoglou, S., . . . Birren, B. W. (2005). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.. Nature, 438(7071), 1105-1115. doi:10.1038/nature04341
Genetic analysis of the TOR pathway in Aspergillus nidulans.
Fitzgibbon, G. J., Morozov, I. Y., Jones, M. G., & Caddick, M. X. (2005). Genetic analysis of the TOR pathway in Aspergillus nidulans.. Eukaryotic cell, 4(9), 1595-1598. doi:10.1128/ec.4.9.1595-1598.2005
The alc-GR system: a modified alc gene switch designed for use in plant tissue culture.
Roberts, G. R., Garoosi, G. A., Koroleva, O., Ito, M., Laufs, P., Leader, D. J., . . . Tomsett, A. B. (2005). The alc-GR system: a modified alc gene switch designed for use in plant tissue culture.. Plant physiology, 138(3), 1259-1267. doi:10.1104/pp.105.059659
Characterization of the ethanol-inducible alc gene expression system in tomato.
Garoosi, G. A., Salter, M. G., Caddick, M. X., & Tomsett, A. B. (2005). Characterization of the ethanol-inducible alc gene expression system in tomato.. Journal of experimental botany, 56(416), 1635-1642. doi:10.1093/jxb/eri159
2004
Nitrogen Regulation in Mycelial Fungi
Caddick, M. X. (2004). Nitrogen Regulation in Mycelial Fungi. In Biochemistry and Molecular Biology (pp. 349-368). Springer Berlin Heidelberg. doi:10.1007/978-3-662-06064-3_17
2003
A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus.
O'Callaghan, J., Caddick, M. X., & Dobson, A. D. W. (2003). A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus.. Microbiology (Reading, England), 149(Pt 12), 3485-3491. doi:10.1099/mic.0.26619-0
Re: Watts et al. Proteins 2002;48:161-168.
Arst, H. N., Nicholas, H. B., & Caddick, M. X. (2003). Re: Watts et al. Proteins 2002;48:161-168.. Proteins, 52(2), 125-128. doi:10.1002/prot.10447
Differential expression of cold- and diet-specific genes encoding two carp liver delta 9-acyl-CoA desaturase isoforms.
Polley, S. D., Tiku, P. E., Trueman, R. T., Caddick, M. X., Morozov, I. Y., & Cossins, A. R. (2003). Differential expression of cold- and diet-specific genes encoding two carp liver delta 9-acyl-CoA desaturase isoforms.. American journal of physiology. Regulatory, integrative and comparative physiology, 284(1), R41-R50. doi:10.1152/ajpregu.00263.2002
2002
The role of desaturases in cold-induced lipid restructuring
Cossins, A. R., Murray, P. A., Gracey, A. Y., Logue, J., Polley, S., Caddick, M., . . . Maclean, N. (2002). The role of desaturases in cold-induced lipid restructuring. BIOCHEMICAL SOCIETY TRANSACTIONS, 30, 1082-1086. doi:10.1042/bst0301082
The role of desaturases in cold-induced lipid restructuring
Cossins, A. R., Murray, P. A., Gracey, A. Y., Logue, J., Polley, S., Caddick, M., . . . Maclean, N. (2002). The role of desaturases in cold-induced lipid restructuring. BIOCHEMICAL SOCIETY TRANSACTIONS, 30, 1082-1086 Part 6.
2001
Characterization of nitrogen metabolite signalling in <i>Aspergillus</i> via the regulated degradation of <i>areA</i> mRNA
Morozov, I. Y., Galbis‐Martinez, M., Jones, M. G., & Caddick, M. X. (2001). Characterization of nitrogen metabolite signalling in <i>Aspergillus</i> via the regulated degradation of <i>areA</i> mRNA. Molecular Microbiology, 42(1), 269-277. doi:10.1046/j.1365-2958.2001.02636.x
Characterization of nitrogen metabolite signalling in Aspergillus via the regulated degradation of areA mRNA.
Morozov, I. Y., Galbis-Martinez, M., Jones, M. G., & Caddick, M. X. (2001). Characterization of nitrogen metabolite signalling in Aspergillus via the regulated degradation of areA mRNA.. Molecular microbiology, 42(1), 269-277. doi:10.1046/j.1365-2958.2001.02636.x
The Aspergillus nidulans GATA transcription factor gene areB encodes at least three proteins and features three classes of mutation.
Conlon, H., Zadra, I., Haas, H., Arst, H. N., Jones, M. G., & Caddick, M. X. (2001). The Aspergillus nidulans GATA transcription factor gene areB encodes at least three proteins and features three classes of mutation.. Molecular microbiology, 40(2), 361-375. doi:10.1046/j.1365-2958.2001.02399.x
The<i>Aspergillus nidulans</i>GATA transcription factor gene<i>areB</i>encodes at least three proteins and features three classes of mutation
Conlon, H., Zadra, I., Haas, H., Arst, H. N., Jones, M. G., & Caddick, M. X. (2001). The<i>Aspergillus nidulans</i>GATA transcription factor gene<i>areB</i>encodes at least three proteins and features three classes of mutation. Molecular Microbiology, 40(2), 361-375. doi:10.1046/j.1365-2958.2001.02399.x
Characterization of the ethanol-inducible alc gene-expression system in Arabidopsis thaliana
Roslan, H. A., Salter, M. G., Wood, C. D., White, M. R. H., Croft, K. P., Robson, F., . . . Caddick, M. X. (2001). Characterization of the ethanol-inducible alc gene-expression system in Arabidopsis thaliana. Plant Journal, 28(2), 225-235.
Evaluating low level sequence identities - Are Aspergillus QUTA and AROM homologous?
Nicholas, H. B., Arst, H. N., & Caddick, M. X. (2001). Evaluating low level sequence identities - Are Aspergillus QUTA and AROM homologous?. European Journal Of Biochemistry, 268(2), 414-419.
2000
Thermal thresholds of lipid restructuring and Δ<SUP>9</SUP>-desaturase expression in the liver of carp (<i>Cyprinus</i> <i>carpio</i> L.)
Trueman, R. J., Tiku, P. E., Caddick, M. X., & Cossins, A. R. (2000). Thermal thresholds of lipid restructuring and Δ<SUP>9</SUP>-desaturase expression in the liver of carp (<i>Cyprinus</i> <i>carpio</i> L.). JOURNAL OF EXPERIMENTAL BIOLOGY, 203(3), 641-650. Retrieved from https://www.webofscience.com/