Publications
2022
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020)
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2022). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020). SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-08813-w
2021
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020)
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2021). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity (vol 10, 17313, 2020). SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-86214-1
2020
Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity
Panagiotou, S., Chaguza, C., Yahya, R., Audshasai, T., Baltazar, M., Ressel, L., . . . Yang, M. (2020). Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-73454-w
Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism
Chaguza, C., Yang, M., Cornick, J. E., du Plessis, M., Gladstone, R. A., Kwambana-Adams, B. A., . . . Bentley, S. D. (2020). Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism. COMMUNICATIONS BIOLOGY, 3(1). doi:10.1038/s42003-020-01290-9
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin
Jacques, L. C., Panagiotou, S., Baltazar, M., Senghore, M., Khandaker, S., Xu, R., . . . Kadioglu, A. (2020). Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-15751-6
2019
Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival
Subramanian, K., Neill, D. R., Malak, H., Spelmink, L., Khandaker, S., Marchiori, G., . . . Henriques-Normark, B. (2019). Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nature Microbiology, 4(1), 62-70. doi:10.1038/s41564-018-0280-x
Pneumolysin interaction with the mannose receptor promotes pneumococcal invasion of the airways by blocking inflammatory responses
Subramanian, K., Neill, D. R., Malak, H. A., Spelmink, L., Khandaker, S., Marchiori, G. D. L., . . . Henriques-Normark, B. (2019). Pneumolysin interaction with the mannose receptor promotes pneumococcal invasion of the airways by blocking inflammatory responses. In SCANDINAVIAN JOURNAL OF IMMUNOLOGY Vol. 90. Retrieved from https://www.webofscience.com/
2017
Comparative genomic analysis and in vivo modelling of Streptococcus pneumoniae ST3081 and ST618 isolates reveal key genetic and phenotypic differences contributing to clonal replacement of serotype 1 in The Gambia.
Bricio-Moreno, L., Ebruke, C., Chaguza, C., Cornick, J., Kwambana-Adams, B., Yang, M., . . . Kadioglu, A. (2017). Comparative genomic analysis and in vivo modelling of Streptococcus pneumoniae ST3081 and ST618 isolates reveal key genetic and phenotypic differences contributing to clonal replacement of serotype 1 in The Gambia.. The Journal of infectious diseases, 216(10), 1318-1327. doi:10.1093/infdis/jix472
2016
Understanding pneumococcal serotype 1 biology through population genomic analysis
Chaguza, C., Cornick, J. E., Harris, S. R., Andam, C. P., Bricio-Moreno, L., Yang, M., . . . Bentley, S. D. (2016). Understanding pneumococcal serotype 1 biology through population genomic analysis. BMC INFECTIOUS DISEASES, 16. doi:10.1186/s12879-016-1987-z
Recombination in <i>Streptococcus pneumoniae</i> Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule
Chaguza, C., Andam, C. P., Harris, S. R., Cornick, J. E., Yang, M., Bricio-Moreno, L., . . . Hanage, W. P. (2016). Recombination in <i>Streptococcus pneumoniae</i> Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule. MBIO, 7(5). doi:10.1128/mBio.01053-16
Pneumococcal Biology, Diversity, Evolution and Host Responses to Infection
Neill, D. R., Yang, M., & Kadioglu, A. (2016). Pneumococcal Biology, Diversity, Evolution and Host Responses to Infection. In ENCYCLOPEDIA OF IMMUNOBIOLOGY, VOL 4: IMMUNITY TO PATHOGENS AND TUMORS (pp. 60-65). doi:10.1016/B978-0-12-374279-7.13019-X
2014
Mitochondrial complex I activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization.
Jin, Z., Wei, W., Yang, M., Du, Y., & Wan, Y. (2014). Mitochondrial complex I activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization.. Cell metabolism, 20(3), 483-498. doi:10.1016/j.cmet.2014.07.011
Elucidation of the pathogenesis of pneumococcal meningitis in a nasopharynx-to-meninges translocation mouse model
Yang, M., Engel, H., Clauzier, L., Riley, L., Pottinger, S., Cornick, J., . . . Kadioglu, A. (2014). Elucidation of the pathogenesis of pneumococcal meningitis in a nasopharynx-to-meninges translocation mouse model. IMMUNOLOGY, 143, 165. Retrieved from https://www.webofscience.com/
Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes.
Meraz, I. M., Hearnden, C. H., Liu, X., Yang, M., Williams, L., Savage, D. J., . . . Serda, R. E. (2014). Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes.. PloS one, 9(4), e94703. doi:10.1371/journal.pone.0094703
2013
Functionalization of carbon nanoparticles modulates inflammatory cell recruitment and NLRP3 inflammasome activation.
Yang, M., Flavin, K., Kopf, I., Radics, G., Hearnden, C. H. A., McManus, G. J., . . . Lavelle, E. C. (2013). Functionalization of carbon nanoparticles modulates inflammatory cell recruitment and NLRP3 inflammasome activation.. Small (Weinheim an der Bergstrasse, Germany), 9(24), 4194-4206. doi:10.1002/smll.201300481
2012
Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity.
Du, Y., Yang, M., Lee, S., Behrendt, C. L., Hooper, L. V., Saghatelian, A., & Wan, Y. (2012). Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity.. Genes & development, 26(12), 1306-1311. doi:10.1101/gad.191031.112
Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.
Bricio-Moreno, L., Chaguza, C., Yahya, R., Shears, R. K., Cornick, J. E., Hokamp, K., . . . Kadioglu, A. (2012). Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.. mBio, 11(6). doi:10.1093/infdis/jis223
Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates.
Du, Y., Yang, M., Wei, W., Huynh, H. D., Herz, J., Saghatelian, A., & Wan, Y. (2012). Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates.. Nature communications, 3, 1008. doi:10.1038/ncomms2011
2010
PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss.
Wei, W., Wang, X., Yang, M., Smith, L. C., Dechow, P. C., Sonoda, J., . . . Wan, Y. (2010). PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss.. Cell metabolism, 11(6), 503-516. doi:10.1016/j.cmet.2010.04.015
Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3- and transforming growth factor-beta-associated mechanisms.
Yang, M., Yang, C., & Mine, Y. (2010). Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3- and transforming growth factor-beta-associated mechanisms.. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 40(4), 668-678. doi:10.1111/j.1365-2222.2009.03442.x
2009
Immunomodulatory effects of egg white enzymatic hydrolysates containing immunodominant epitopes in a BALB/c mouse model of egg allergy.
Yang, M., Yang, C., Nau, F., Pasco, M., Juneja, L. R., Okubo, T., & Mine, Y. (2009). Immunomodulatory effects of egg white enzymatic hydrolysates containing immunodominant epitopes in a BALB/c mouse model of egg allergy.. Journal of agricultural and food chemistry, 57(6), 2241-2248. doi:10.1021/jf803372b
Novel T-cell epitopes of ovalbumin in BALB/c mouse: potential for peptide-immunotherapy.
Yang, M., & Mine, Y. (2009). Novel T-cell epitopes of ovalbumin in BALB/c mouse: potential for peptide-immunotherapy.. Biochemical and biophysical research communications, 378(2), 203-208. doi:10.1016/j.bbrc.2008.11.037
2008
Recent advances in the understanding of egg allergens: basic, industrial, and clinical perspectives.
Mine, Y., & Yang, M. (2008). Recent advances in the understanding of egg allergens: basic, industrial, and clinical perspectives.. Journal of agricultural and food chemistry, 56(13), 4874-4900. doi:10.1021/jf8001153
2007
Proteomic analysis of ovomucoid hypersensitivity in mice by two-dimensional difference gel electrophoresis (2D-DIGE).
Hobson, D. J., Rupa, P., Diaz, G. J., Zhang, H., Yang, M., Mine, Y., . . . Kirby, G. M. (2007). Proteomic analysis of ovomucoid hypersensitivity in mice by two-dimensional difference gel electrophoresis (2D-DIGE).. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(12), 2372-2380. doi:10.1016/j.fct.2007.06.039
Epitope characterization of ovalbumin in BALB/c mice using different entry routes.
Mine, Y., & Yang, M. (2007). Epitope characterization of ovalbumin in BALB/c mice using different entry routes.. Biochimica et biophysica acta, 1774(2), 200-212. doi:10.1016/j.bbapap.2006.12.003