Publications
2024
Magnetic particle imaging: The need for standardized approaches
Poptani, H., O’Brien, L., & Giardiello, M. (2024). Magnetic particle imaging: The need for standardized approaches. Matter, 7(8), 2718-2720. doi:10.1016/j.matt.2024.05.049
2023
Controllable and tuneable growth of NaYbF<sub>4</sub>:Tm(0.5%)Fe(5%)@Na(Yb/Y)F<sub>4</sub>-core@shell structures and the effect of their geometry on upconversion luminescence
Urena-Horno, E., Liu, K., & Giardiello, M. (2023). Controllable and tuneable growth of NaYbF<sub>4</sub>:Tm(0.5%)Fe(5%)@Na(Yb/Y)F<sub>4</sub>-core@shell structures and the effect of their geometry on upconversion luminescence. JOURNAL OF MATERIALS CHEMISTRY C. doi:10.1039/d3tc01215h
2022
Aqueous (co)polymer stabilisers for size-controlled 2-5 nm gold nanoparticle synthesis with tuneable catalytic activity
Traynor, D. J., Urena-Horno, E., Hobson, J. J., Croft, E. J., Edwards, S. E., Rannard, S. P., & Giardiello, M. (2022). Aqueous (co)polymer stabilisers for size-controlled 2-5 nm gold nanoparticle synthesis with tuneable catalytic activity. NEW JOURNAL OF CHEMISTRY, 46(36), 17282-17291. doi:10.1039/d2nj03257k
2019
Nanomedicines towards targeting intracellular <i>Mtb</i> for the treatment of tuberculosis
Donnellan, S., & Giardiello, M. (2019). Nanomedicines towards targeting intracellular <i>Mtb</i> for the treatment of tuberculosis. Journal of Interdisciplinary Nanomedicine, 4(3), 76-85. doi:10.1002/jin2.61
2018
Barriers for the development, translation, and implementation of nanomedicine: an African perspective
Saravanan, M., Ramachandran, B., Hamed, B., & Giardiello, M. (n.d.). Barriers for the development, translation, and implementation of nanomedicine: an African perspective. Journal of Interdisciplinary Nanomedicine. doi:10.1002/jin2.43
Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems
Liptrott, N. J., Giardiello, M., McDonald, T. O., Rannard, S. P., & Owen, A. (2018). Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems. JOURNAL OF NANOBIOTECHNOLOGY, 16. doi:10.1186/s12951-018-0349-y
2017
In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line
Curley, P., Giardiello, M., Liptrott, N. J., Dickens, D., Moss, D. M., Hobson, J. J., . . . Owen, A. (2017). In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line. Journal of Interdisciplinary Nanomedicine, 2(3), 157-169. doi:10.1002/jin2.32
Intracellular delivery of nano-formulated antituberculosis drugs enhances bactericidal activity
Donnellan, S., Stone, V., Johnston, H., Giardiello, M., Owen, A., Rannard, S., . . . Stevenson, K. (2017). Intracellular delivery of nano-formulated antituberculosis drugs enhances bactericidal activity. Journal of Interdisciplinary Nanomedicine, 2(3), 146-156. doi:10.1002/jin2.27
Lack of interaction of lopinavir solid drug nanoparticles with cells of the immune system
Liptrott, N. J., Giardiello, M., McDonald, T. O., Rannard, S. P., & Owen, A. (2017). Lack of interaction of lopinavir solid drug nanoparticles with cells of the immune system. NANOMEDICINE, 12(17), 2043-2054. doi:10.2217/nnm-2017-0095
Dual-stimuli responsive injectable nanogel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs
Town, A., Gurjar, R., Giardiello, M., Briggs, M., Akhtar, R., Siccardi, M., & McDonald, T. (2017). Dual-stimuli responsive injectable nanogel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 254. doi:10.1039/C6NR07858C
Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs
Town, A. R., Giardiello, M., Gurjar, R., Siccardi, M., Briggs, M. E., Akhtar, R., & McDonald, T. O. (2017). Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs. Nanoscale, 9(19), 6302-6314. doi:10.1039/c6nr07858c
Assessment of the potential interactions of hyperbranched polydendrons with immunological and haematological systems.
David, C., Giardiello, M., Rannard, S. P., Owen, A., & Liptrott, N. J. (2017). Assessment of the potential interactions of hyperbranched polydendrons with immunological and haematological systems.. Poster session presented at the meeting of BSNM Early Career Researchers' Meeting. Belfast.
Six year manufacturing to human clinical trial programme for the first oral dosed HIV nanomedicines
Giardiello, M., McDonald, T., Liptrott, N., Martin, P., Smith, D., Siccardi, M., . . . Rannard, S. (2017). Six year manufacturing to human clinical trial programme for the first oral dosed HIV nanomedicines. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 254. Retrieved from https://www.webofscience.com/
2016
Accelerated oral nanomedicine discovery from miniaturized screening to clinical production exemplified by paediatric HIV nanotherapies
Giardiello, M., Liptrott, M. J., McDonald, T. O., Moss, D., Siccardi, M., Martin, P., . . . Owen, A. (2016). Accelerated oral nanomedicine discovery from miniaturized screening to clinical production exemplified by paediatric HIV nanotherapies. Nature Communications, 7. doi:10.1038/ncomms13184
Towards a rational design of solid drug nanoparticles with optimised pharmacological properties.
Siccardi, M., Martin, P., Smith, D., Curley, P., McDonald, T., Giardiello, M., . . . Owen, A. (2016). Towards a rational design of solid drug nanoparticles with optimised pharmacological properties.. Journal of interdisciplinary nanomedicine, 1(3), 110-123. doi:10.1002/jin2.21
Early Investigation of the Stabilisation Effects of Polymer and Surfactant Combinations in the Formulation of Solid Drug Nanoparticles
Savage, A. C., Giardiello, M., Owen, A., & Rannard, S. (2016). Early Investigation of the Stabilisation Effects of Polymer and Surfactant Combinations in the Formulation of Solid Drug Nanoparticles. In British Society of Nanomedicine Early Career Meeting Vol. 1 (pp. 78). Swansea University. doi:10.1002/jin2.14
Early Investigation of the Stabilisation Effects of Polymer and Surfactant Combinations in the Formulation of Solid Drug Nanoparticles
Savage, A. C., Giardiello, M., Owen, A., & Rannard, S. P. (2016). Early Investigation of the Stabilisation Effects of Polymer and Surfactant Combinations in the Formulation of Solid Drug Nanoparticles. Poster session presented at the meeting of Royal Society of Chemistry Early Career Symposium. University of Strathclyde.
Stable, polymer-directed and SPION-nucleated magnetic amphiphilic block copolymer nanoprecipitates with readily reversible assembly in magnetic fields
Giardiello, M., Hatton, F. L., Slater, R. A., Chambon, P., North, J., Peacock, A. K., . . . Rannard, S. P. (2016). Stable, polymer-directed and SPION-nucleated magnetic amphiphilic block copolymer nanoprecipitates with readily reversible assembly in magnetic fields. Nanoscale, 8(13), 7224-7231. doi:10.1039/c6nr00788k
2015
Augmented Inhibition of CYP3A4 in Human Primary Hepatocytes by Ritonavir Solid Drug Nanoparticles
Martin, P., Giardiello, M., McDonald, T. C., Smith, D., Siccardi, M., Rannard, S. P., & Owen, A. (2015). Augmented Inhibition of CYP3A4 in Human Primary Hepatocytes by Ritonavir Solid Drug Nanoparticles. MOLECULAR PHARMACEUTICS, 12(10), 3556-3568. doi:10.1021/acs.molpharmaceut.5b00204
The Application of Nanotechnology to Drug Delivery in Medicine
McDonald, T. O., Siccardi, M., Moss, D., Liptrott, N., Giardiello, M., Rannard, S., & Owen, A. (2015). The Application of Nanotechnology to Drug Delivery in Medicine. In Nanoengineering (pp. 173-223). Elsevier. doi:10.1016/b978-0-444-62747-6.00007-5
Flow cytometric analysis of the physical and protein-binding characteristics of solid drug nanoparticle suspensions
Liptrott, N. J., Giardiello, M., Hunter, J. W., Tatham, L., Tidbury, L. R., Siccardi, M., . . . Owen, A. (2015). Flow cytometric analysis of the physical and protein-binding characteristics of solid drug nanoparticle suspensions. NANOMEDICINE, 10(9), 1407-1421. doi:10.2217/NNM.14.77
Multiple and Co-Nanoprecipitation Studies of Branched Hydrophobic Copolymers and A-B Amphiphilic Block Copolymers, Allowing Rapid Formation of Sterically Stabilized Nanoparticles in Aqueous Media
Ford, J., Chambon, P., North, J., Hatton, F. L., Giardiello, M., Owen, A., & Rannard, S. P. (2015). Multiple and Co-Nanoprecipitation Studies of Branched Hydrophobic Copolymers and A-B Amphiphilic Block Copolymers, Allowing Rapid Formation of Sterically Stabilized Nanoparticles in Aqueous Media. MACROMOLECULES, 48(6), 1883-1893. doi:10.1021/acs.macromol.5b00099
2014
Antiretroviral Solid Drug Nanoparticles with Enhanced Oral Bioavailability: Production, Characterization, and In Vitro–In Vivo Correlation
McDonald, T. O., Giardiello, M., Martin, P., Siccardi, M., Liptrott, N. J., Roberts, P., . . . Owen, A. (2014). Antiretroviral Solid Drug Nanoparticles with Enhanced Oral Bioavailability: Production, Characterization, and In Vitro–In Vivo Correlation. Advanced Healthcare Materials, 3(3), 400-411. doi:10.1002/adhm.201300280
<i>In vitro</i> characterization of efavirenz-containing solid drug nanoparticles
King, S. C., Oliveira, M., Moisi, D., Brenner, B., Giardiello, M., Rannard, S. P., . . . Geretti, A. M. (2014). <i>In vitro</i> characterization of efavirenz-containing solid drug nanoparticles. In ANTIVIRAL THERAPY Vol. 19 (pp. A126). Retrieved from https://www.webofscience.com/
Flow cytometric analysis of the physical and protein-binding characteristics of solid drug nanoparticle suspensions
Liptrott, N., Giardiello, M., Hunter, J. W., Tatham, L., Tidbury, L. R., Siccardi, M., . . . Owen, A. (2014). Flow cytometric analysis of the physical and protein-binding characteristics of solid drug nanoparticle suspensions. Nanomedicine (London).
The in vivo effects of solid drug nanoparticle and conventional efavirenz on anxiogenesis in rodents
Curley, P., Giardiello, M., Liptrott, N., Martin, P., McDonald, T., Siccardi, M., . . . Owen, A. (2014). The in vivo effects of solid drug nanoparticle and conventional efavirenz on anxiogenesis in rodents. Poster session presented at the meeting of 21st Conference on Retroviruses and Opportunistic Infections. Boston, USA.
2013
pH-Responsive Lanthanide Complexes Based on Reversible Ligation of a Diphenylphosphinamide
Giardiello, M., Botta, M., & Lowe, M. P. (2013). pH-Responsive Lanthanide Complexes Based on Reversible Ligation of a Diphenylphosphinamide. INORGANIC CHEMISTRY, 52(24), 14264-14269. doi:10.1021/ic402205j
High-throughput nanoprecipitation of the organic antimicrobial triclosan and enhancement of activity against <i>Escherichia coli</i>
McDonald, T. O., Tatham, L. M., Southworth, F. Y., Giardiello, M., Martin, P., Liptrott, N. J., . . . Rannard, S. P. (2013). High-throughput nanoprecipitation of the organic antimicrobial triclosan and enhancement of activity against <i>Escherichia coli</i>. JOURNAL OF MATERIALS CHEMISTRY B, 1(35), 4455-4465. doi:10.1039/c3tb20543f
Mediation of in Vitro Cytochrome P450 Activity by Common Pharmaceutical Excipients
Martin, P., Giardiello, M., McDonald, T. O., Rannard, S. P., & Owen, A. (2013). Mediation of in Vitro Cytochrome P450 Activity by Common Pharmaceutical Excipients. MOLECULAR PHARMACEUTICS, 10(7), 2739-2748. doi:10.1021/mp400175n
Compositions of Lopinavir and Ritonavir
Rannard, S., Owen, A., Smith, D., Giardiello, M., McDonald, T., & Martin, P. (2013). Compositions of Lopinavir and Ritonavir.
HIV Drug Nanodispersions
Rannard, S., Owen, A., Giardiello, M., McDonald, T., Smith, D., & Martin, P. (2013). HIV Drug Nanodispersions.
Nanoparticles Formulation of Lopinavir
Rannard, S., Owen, A., Smith, S., Giardiello, M., McDonald, T., Martin, P., & Long, J. (2013). Nanoparticles Formulation of Lopinavir.
Enhanced Pharmacological Properties of Efavirenz Formulated as Solid Drug Nanoparticles
Martin, P., Liptrott, N., McDonald, T., Giardiello, M., Roberts, P., Curley, P., . . . Owen, A. (2013). Enhanced Pharmacological Properties of Efavirenz Formulated as Solid Drug Nanoparticles. In 20th Conference on Retroviruses and Opportunistic Infections. Atlanta, USA.
High-throughput nanoprecipitation of the organic antimicrobial triclosan and enhancement of activity against Escherichia coli
McDonald, T. O., Tatham, L. M., Southworth, F. Y., Giardiello, M., Martin, P., Liptrott, N. J., . . . Rannard, S. P. (2013). High-throughput nanoprecipitation of the organic antimicrobial triclosan and enhancement of activity against Escherichia coli. Journal of Materials Chemistry B, 1(35), 4455. doi:10.1039/c3tb20543f
Nanomedicines for HIV therapy.
Siccardi, M., Martin, P., McDonald, T. O., Liptrott, N. J., Giardiello, M., Rannard, S., & Owen, A. (2013). Nanomedicines for HIV therapy.. Therapeutic delivery, 4(2), 153-156. doi:10.4155/tde.12.156
Reactions of hydrophobic organic nanoparticle mixtures in water: nanoparticle-on-nanoparticle oxidative dye bleaching
Giardiello, M., McDonald, T. O., Lee, J. -S., Roberts, A. D., Owen, A., & Rannard, S. P. (2013). Reactions of hydrophobic organic nanoparticle mixtures in water: nanoparticle-on-nanoparticle oxidative dye bleaching. GREEN CHEMISTRY, 15(6), 1590-1599. doi:10.1039/c3gc40573g
2012
Facile synthesis of complex multi-component organic and organic-magnetic inorganic nanocomposite particles
Giardiello, M., McDonald, T. O., Martin, P., Owen, A., & Rannard, S. P. (2012). Facile synthesis of complex multi-component organic and organic-magnetic inorganic nanocomposite particles. JOURNAL OF MATERIALS CHEMISTRY, 22(47), 24744-24752. doi:10.1039/c2jm34974d
Multicomponent Organic Nanoparticles for Fluorescence Studies in Biological Systems
McDonald, T. O., Martin, P., Patterson, J. P., Smith, D., Giardiello, M., Marcello, M., . . . Rannard, S. (2012). Multicomponent Organic Nanoparticles for Fluorescence Studies in Biological Systems. ADVANCED FUNCTIONAL MATERIALS, 22(12), 2469-2478. doi:10.1002/adfm.201103059
Rapid "bottom-up" production of organic nanoparticles: From drug bioavailability enhancement to fluorescence studies of cellular accumulation
Rannard, S. P., McDonald, T. O., Owen, A., Giardiello, M., Martin, P., & Liptrot, N. (2012). Rapid "bottom-up" production of organic nanoparticles: From drug bioavailability enhancement to fluorescence studies of cellular accumulation. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244. Retrieved from https://www.webofscience.com/
2011
Synthesis of lanthanide(III) complexes appended with a diphenylphosphinamide and their interaction with human serum albumin
Giardiello, M., Botta, M., & Lowe, M. P. (2011). Synthesis of lanthanide(III) complexes appended with a diphenylphosphinamide and their interaction with human serum albumin. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 71(3-4), 435-444. doi:10.1007/s10847-011-0009-4
Cell-Permeable Ln(III) Chelate-Functionalized InP Quantum Dots As Multimodal Imaging Agents
Stasiuk, G. J., Tamang, S., Imbert, D., Poillot, C., Giardiello, M., Tisseyre, C., . . . Mazzanti, M. (2011). Cell-Permeable Ln(III) Chelate-Functionalized InP Quantum Dots As Multimodal Imaging Agents. ACS NANO, 5(10), 8193-8201. doi:10.1021/nn202839w
Compositions of Lopinavir & Ritonavir
Rannard, S., Owen, A., Smith, D., Giardiello, M., McDonald, T., & Martin, P. (2011). Compositions of Lopinavir & Ritonavir.
HIV Drug Nanodispersions
Rannard, S., Owen, A., McDonald, T., Smith, D., Giardiello, M., & Martin, P. (2011). HIV Drug Nanodispersions.
Nanoparticles Formulation of Lopinavir
Rannard, S., Owen, A., Smith, D., Giardiello, M., McDonald, T., Martin, P., & Long, J. (2011). Nanoparticles Formulation of Lopinavir.
2010
Influence of particle size and surface charge on the cytotoxicity of nanodispersions
Martin, P., McDonald, T., Smith, D., Giardiello, M., Rannard, S., & Owen, A. (2010). Influence of particle size and surface charge on the cytotoxicity of nanodispersions. DRUG METABOLISM REVIEWS, 42, 50-51. Retrieved from https://www.webofscience.com/
2009
Luminescence Study of Eu(III) Analogues of Esterase-Activated Magnetic Resonance Contrast Agents
Giardiello, M., & Lowe, M. P. (2009). Luminescence Study of Eu(III) Analogues of Esterase-Activated Magnetic Resonance Contrast Agents. INORGANIC CHEMISTRY, 48(17), 8515-8522. doi:10.1021/ic901284t
2007
An esterase-activated magnetic resonance contrast agent
Giardiello, M., Lowe, M. P., & Botta, M. (2007). An esterase-activated magnetic resonance contrast agent. CHEMICAL COMMUNICATIONS, (39), 4044-4046. doi:10.1039/b711989e
2003
Room-temperature cyclometallation of amines, imines and oxazolines with [MCl<sub>2</sub>Cp*]<sub>2</sub> (M = Rh, Ir) and [RuCl<sub>2</sub>(<i>p</i>-cymene)]<sub>2</sub>
Davies, D. L., Al-Duaij, O., Fawcett, J., Giardiello, M., Hilton, S. T., & Russell, D. R. (2003). Room-temperature cyclometallation of amines, imines and oxazolines with [MCl<sub>2</sub>Cp*]<sub>2</sub> (M = Rh, Ir) and [RuCl<sub>2</sub>(<i>p</i>-cymene)]<sub>2</sub>. DALTON TRANSACTIONS, (21), 4132-4138. doi:10.1039/b303737a
2001
Redox behavior of boronato-functionalized 1,1′-bis(diphenylphosphino)ferrocenes
Zanello, P., Cinquantini, A., Fontani, M., Giardiello, M., Giorgi, G., Landis, C. R., & Kimmich, B. F. M. (2001). Redox behavior of boronato-functionalized 1,1′-bis(diphenylphosphino)ferrocenes. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 637, 800-804. doi:10.1016/S0022-328X(01)01132-9