Publications
Selected publications
- Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics (Journal article - 2020)
- SnoRNA signatures in cartilage ageing and osteoarthritis. (Journal article - 2020)
- Metabolomic and Proteomic Stratification of Equine Osteoarthritis (Journal article - 2020)
- THE ROLE OF SNORD116 IN CARTILAGE AGEING AND OSTEOARTHRITIS (Conference Paper - 2020)
- Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study (Journal article - 2020)
- Epigenetic mechanisms in tendon ageing (Journal article - 2020)
- The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion. (Journal article - 2019)
- Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to diagnose osteoarthritis in equine serum. (Journal article - 2019)
- RIBOSOMAL PROFILING AND SECRETOME ANALYSIS IDENTIFY THAT INTERLEUKIN-1B DRIVEN CYTOKINE/CHEMOKINE RELEASE FROM CHONDROCYTIC CELLS IS UNDERPINNED BY DIFFERENTIAL TRANSLATION (Conference Paper - 2018)
- Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females (Journal article - 2017)
2024
Defining an ageing-related pathology, disease or syndrome: International Consensus Statement.
Short, E., ICCARP., Calimport, S., & Bentley, B. (2024). Defining an ageing-related pathology, disease or syndrome: International Consensus Statement.. GeroScience. doi:10.1007/s11357-024-01315-9
Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement.
Lifelong dietary protein restriction induces denervation and skeletal muscle atrophy in mice.
Ersoy, U., Altinpinar, A. E., Kanakis, I., Alameddine, M., Gioran, A., Chondrogianni, N., . . . Vasilaki, A. (2024). Lifelong dietary protein restriction induces denervation and skeletal muscle atrophy in mice.. Free radical biology & medicine, S0891-5849(24)00648-8. doi:10.1016/j.freeradbiomed.2024.09.005
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2024.
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2024. (2024). In Equine veterinary journal Vol. 56 Suppl 59 (pp. 11-12). doi:10.1111/evj.14151
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2024.
Clinical Research Abstracts of the British Equine Veterinary Association Congress 2024. (2024). In Equine veterinary journal Vol. 56 Suppl 59 (pp. 13). doi:10.1111/evj.14153
Allogenic platelet-rich plasma and platelet-rich plasma extracellular vesicles alter the proteome of tenocytes in an in vitro equine model of tendon inflammation: A pilot study
Lifelong protein restriction induces denervation and increases proteasomal activity in skeletal muscle
Ersoy, U., Altinpinar, A. E., Alameddine, M., Kanakis, I., Peffers, M. J., Ozanne, S. E., . . . Vasilaki, A. (2024). Lifelong protein restriction induces denervation and increases proteasomal activity in skeletal muscle. Free Radical Biology and Medicine, 218, 38. doi:10.1016/j.freeradbiomed.2024.04.138
TGF-β2 Induces Ribosome Activity, Alters Ribosome Composition and Inhibits IRES-Mediated Translation in Chondrocytes.
van den Akker, G. G. H., Chabronova, A., Housmans, B. A. C., van der Vloet, L., Surtel, D. A. M., Cremers, A., . . . Welting, T. J. M. (2024). TGF-β2 Induces Ribosome Activity, Alters Ribosome Composition and Inhibits IRES-Mediated Translation in Chondrocytes.. International journal of molecular sciences, 25(9), 5031. doi:10.3390/ijms25095031
Equine odontoclastic tooth resorption and hypercementosis
Nugent, Z., Paice, E., Jensen, A., & Peffers, M. (2024). Equine odontoclastic tooth resorption and hypercementosis. UK-Vet Equine, 8(3), 146-150. doi:10.12968/ukve.2024.8.3.146
Identification of canine cruciate ligament microRNA:mRNA interactome to determine mechanistic pathways in canine cruciate ligament disease
Jeyaseelan, S., Peffers, M., Ashraf-Kharaz, Y., & Comerford, E. (2024). Identification of canine cruciate ligament microRNA:mRNA interactome to determine mechanistic pathways in canine cruciate ligament disease. In BSAVA Congress Proceedings 2024. British Small Animal Veterinary Association. doi:10.22233/9781913859411.45.1
Plasma and synovial fluid extracellular vesicles display altered microRNA profiles in horses with naturally occurring post-traumatic osteoarthritis: an exploratory study.
Connard, S. S., Gaesser, A. M., Clarke, E. J., Linardi, R. L., Even, K. M., Engiles, J. B., . . . Ortved, K. F. (2024). Plasma and synovial fluid extracellular vesicles display altered microRNA profiles in horses with naturally occurring post-traumatic osteoarthritis: an exploratory study.. Journal of the American Veterinary Medical Association, 1-12. doi:10.2460/javma.24.02.0102
185 IDENTIFICATION OF SMALL NON-CODING RNAS IN CANINE ANTERIOR CRUCIATE LIGAMENT DISEASE AS DIAGNOSTIC MARKERS AND FUTURE THERAPEUTIC TARGETS
Ashraf- Kharaz, Y., Mullins, R., Muir, P., Sample, S., Cookson, D., Maddox, T., . . . Comerford, E. (2024). 185 IDENTIFICATION OF SMALL NON-CODING RNAS IN CANINE ANTERIOR CRUCIATE LIGAMENT DISEASE AS DIAGNOSTIC MARKERS AND FUTURE THERAPEUTIC TARGETS. Osteoarthritis and Cartilage, 32, S138. doi:10.1016/j.joca.2024.02.196
EXPLOITING ACTIVITY-BASED PROBES TO IDENTIFY SERINE PROTEASE ACTIVITY IN OSTEOARTHRITIS
Hines, M., Wright, M., Bou-Gharios, G., Peffers, M., & Wilkinson, D. J. (2024). EXPLOITING ACTIVITY-BASED PROBES TO IDENTIFY SERINE PROTEASE ACTIVITY IN OSTEOARTHRITIS. Osteoarthritis and Cartilage, 32, S476. doi:10.1016/j.joca.2024.02.707
PROTEOMIC CHARACTERIZATION OF REGENERATED CARTILAGE AFTER KNEE JOINT DISTRACTION, A HUMAN CASE-STUDY
Steijns, J., Caron, M., Emans, P., Boymans, T., Stassen, R., Akker, G. V. D., . . . Welting, T. (2024). PROTEOMIC CHARACTERIZATION OF REGENERATED CARTILAGE AFTER KNEE JOINT DISTRACTION, A HUMAN CASE-STUDY. Osteoarthritis and Cartilage, 32, S462. doi:10.1016/j.joca.2024.02.686
SnoRNAs in cardiovascular development, function, and disease.
Chabronova, A., Holmes, T. L., Hoang, D. M., Denning, C., James, V., Smith, J. G. W., & Peffers, M. J. (2024). SnoRNAs in cardiovascular development, function, and disease.. Trends in molecular medicine, S1471-4914(24)00059-5. doi:10.1016/j.molmed.2024.03.004
Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory 'multi-omics' study to identify composite biomarkers.
Clarke, E., Varela, L., Jenkins, R. E., Lozano-Andrés, E., Cywińska, A., Przewozny, M., . . . Wauben, M. H. M. (2024). Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory 'multi-omics' study to identify composite biomarkers.. Biochemistry and biophysics reports, 37, 101635. doi:10.1016/j.bbrep.2023.101635
Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles.
Brown, T. J., Rutland, C. S., Choi, K. K., Tse, F., Peffers, M. J., Mongan, N. P., . . . James, V. (2024). Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles.. Frontiers in cell and developmental biology, 12, 1354606. doi:10.3389/fcell.2024.1354606
Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.
Ersoy, U., Kanakis, I., Alameddine, M., Pedraza-Vazquez, G., Ozanne, S. E., Peffers, M. J., . . . Vasilaki, A. (2024). Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.. Redox biology, 69, 102980. doi:10.1016/j.redox.2023.102980
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes.
Johnson, B. B., Cosson, M. -V., Tsansizi, L. I., Holmes, T. L., Gilmore, T., Hampton, K., . . . Smith, J. G. W. (2024). Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes.. Cell reports, 43(1), 113668. doi:10.1016/j.celrep.2023.113668
Current evidence for non-pharmaceutical, non-surgical treatments of canine osteoarthritis
Pye, C., Clark, N., Bruniges, N., Peffers, M., & Comerford, E. (n.d.). Current evidence for non-pharmaceutical, non-surgical treatments of canine osteoarthritis. Journal of Small Animal Practice. doi:10.1111/jsap.13670
2023
Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis
Kharaz-Ashraf, Y., Zamboulis, D., Fang, Y., Welting, T., Peffers, M., & Comerford, E. (2023). Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2023.1266088
Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament rupture.
Pye, C., Green, D., Anderson, J., Fitzgerald, M., Phelan, M., Comerford, E., & Peffers, M. (2023). Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament rupture.. Journal of Small Animal Practice.
SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS
Wright, K., McDonald, J., Mennan, C., Perry, J., Peffers, M., & Hulme, C. (2023). SYNOVIAL FLUID PROTEOMICS AND BIOINFORMATICS HIGHLIGHTS POTENTIAL MECHANISMS OF UMBILICAL CORD-MSC INDUCED RADIOLOGICAL IMPROVEMENT IN AN OVINE MODEL OF OSTEOARTHRITIS. Orthopaedic Proceedings, 105-B(SUPP_16), 53. doi:10.1302/1358-992x.2023.16.053
Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age.
Turlo, A. J., Hammond, D. E., Ramsbottom, K. A., Soul, J., Gillen, A., McDonald, K., & Peffers, M. J. (2023). Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age.. Stem cells (Dayton, Ohio), 41(11), 1047-1059. doi:10.1093/stmcls/sxad060
Extracellular vesicles in osteoarthritis: from biomarkers to therapeutic potential
Clarke, E. J., & Peffers, M. J. (2023). Extracellular vesicles in osteoarthritis: from biomarkers to therapeutic potential. UK-Vet Equine, 7(6), 254-259. doi:10.12968/ukve.2023.7.6.254
Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis
Ersoy, U., Vasilaki, A., Jackson, M., Kanakis, I., Peffers, M. J., & Goljanek-Whysall, K. (2023). Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis. Free Radical Biology and Medicine, 208, S65. doi:10.1016/j.freeradbiomed.2023.10.146
Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis.
Anderson, J. R., Johnson, E., Jenkins, R., Jacobsen, S., Green, D., Walters, M., . . . Peffers, M. J. (2023). Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis.. International journal of molecular sciences, 24(19), 14888. doi:10.3390/ijms241914888
Depletion of <i>SNORA33</i> Abolishes ψ of 28S-U4966 and Affects the Ribosome Translational Apparatus
Chabronova, A., van den Akker, G., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2023). Depletion of <i>SNORA33</i> Abolishes ψ of 28S-U4966 and Affects the Ribosome Translational Apparatus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(16). doi:10.3390/ijms241612578
Cartilage-specific <i>Sirt6</i> deficiency represses IGF-1 and enhances osteoarthritis severity in mice.
Collins, J. A., Kim, C. J., Coleman, A., Little, A., Perez, M. M., Clarke, E. J., . . . Loeser, R. F. (2023). Cartilage-specific <i>Sirt6</i> deficiency represses IGF-1 and enhances osteoarthritis severity in mice.. Annals of the rheumatic diseases, ard-2023-224385. doi:10.1136/ard-2023-224385
Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory ‘multi-omics’ study to identify composite biomarkers
Unravelling the Basic Calcium Phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling.
Stassen, R. H. M. J., van den Akker, G. G. H., Surtel, D. A. M., Housmans, B. A. C., Cremers, A., Caron, M. M. J., . . . Welting, T. J. M. (2023). Unravelling the Basic Calcium Phosphate crystal-dependent chondrocyte protein secretome; a role for TGF-β signaling.. Osteoarthritis and cartilage, 31(8), 1035-1046. doi:10.1016/j.joca.2023.02.079
Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening
Hulme, C. H., Peffers, M. J., Roberts, S., Gallacher, P., Jermin, P., & Wright, K. T. (2023). Proteomic Analyses of Autologous Chondrocyte Implantation Plasma Highlight Cartilage Acidic Protein 1 as a Candidate for Preclinical Screening. AMERICAN JOURNAL OF SPORTS MEDICINE, 51(6), 1422-1433. doi:10.1177/03635465231156616
MicroRNA Signatures in Cartilage Ageing and Osteoarthritis
Balaskas, P., Goljanek-Whysall, K., Clegg, P. D., Fang, Y., Cremers, A., Smagul, A., . . . Peffers, M. J. (2023). MicroRNA Signatures in Cartilage Ageing and Osteoarthritis. BIOMEDICINES, 11(4). doi:10.3390/biomedicines11041189
MICRORNA BIOMARKERS IN EQUINE DISTAL INTERPHALANGEAL OSTEOARTHRITIS
Baker, M. E., Clinton, M., Lee, S., Castanheira, C., Peffers, M. J., & Taylor, S. E. (2023). MICRORNA BIOMARKERS IN EQUINE DISTAL INTERPHALANGEAL OSTEOARTHRITIS. Orthopaedic Proceedings, 105-B(SUPP_8), 147. doi:10.1302/1358-992x.2023.8.147
SMALL NON-CODING RNA LANDSCAPE OF EXTRACELLULAR VESICLES FROM AN EXPERIMENTAL MODEL OF EQUINE OSTEOARTHRITIS
Peffers, M., Anderson, J., Jacobsen, S., Walters, M., Bundgaard, L., Hackle, M., & James, V. (2023). SMALL NON-CODING RNA LANDSCAPE OF EXTRACELLULAR VESICLES FROM AN EXPERIMENTAL MODEL OF EQUINE OSTEOARTHRITIS. Orthopaedic Proceedings, 105-B(SUPP_8), 119. doi:10.1302/1358-992x.2023.8.119
Analysis of RNA Polyadenylation in Healthy and Osteoarthritic Human Articular Cartilage
Winstanley-Zarach, P., Rot, G., Kuba, S., Smagul, A., Peffers, M. J. J., & Tew, S. R. R. (2023). Analysis of RNA Polyadenylation in Healthy and Osteoarthritic Human Articular Cartilage. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(7). doi:10.3390/ijms24076611
CARTILAGE-SPECIFIC <i>SIRT6</i> LOSS INCREASES SURGERY-INDUCED AND AGE-ASSOCIATED OA IN MICE
Collins, J. A., Kim, C., Coleman, A., Little, A., Kelley, K., Chubinskaya, S., . . . Loeser, R. (2023). CARTILAGE-SPECIFIC <i>SIRT6</i> LOSS INCREASES SURGERY-INDUCED AND AGE-ASSOCIATED OA IN MICE. In OSTEOARTHRITIS AND CARTILAGE Vol. 31 (pp. S24). Retrieved from https://www.webofscience.com/
EXTRACELLULAR VESICLE MICRORNA CROSSTALK BETWEEN EQUINE CHONDROCYTES AND SYNOVIOCYTES - AN <i>IN VITRO</i> APPROACH
Castanheira, C. I., Anderson, J. R., Clarke, E. J., Taylor, S. E., Hackl, M., Clegg, P., . . . Peffers, M. J. (2023). EXTRACELLULAR VESICLE MICRORNA CROSSTALK BETWEEN EQUINE CHONDROCYTES AND SYNOVIOCYTES - AN <i>IN VITRO</i> APPROACH. In OSTEOARTHRITIS AND CARTILAGE Vol. 31 (pp. S338). Retrieved from https://www.webofscience.com/
FAT PAD ALTERATIONS WITH AGEING AND OSTEOARTHRITIS IN AN OVINE MODEL
Bernard, A., Vandeweerd, J. -M., Simon, V., Houbotte, D., Peffers, M. J., Welting, T., & Hontoir, F. (2023). FAT PAD ALTERATIONS WITH AGEING AND OSTEOARTHRITIS IN AN OVINE MODEL. In OSTEOARTHRITIS AND CARTILAGE Vol. 31 (pp. S317-S318). Retrieved from https://www.webofscience.com/
REGENERATIVE POTENTIAL OF EXTRACELLULAR VESICLES FROM MULTIPLE SOURCES
Anderson, J., Riasat, K., James, V., & Peffers, M. J. (2023). REGENERATIVE POTENTIAL OF EXTRACELLULAR VESICLES FROM MULTIPLE SOURCES. OSTEOARTHRITIS AND CARTILAGE, 31, S234. Retrieved from https://www.webofscience.com/
Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis
Chabronova, A., van den Akker, G. G. H., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2023). Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis. OSTEOARTHRITIS AND CARTILAGE, 31(3), 374-385. doi:10.1016/j.joca.2022.12.010
TEMPORAL PROTEOMIC LANDSCAPE OF PLASMA AND SYNOVIAL FLUID DERIVED EXTRACELLULAR VESICLES USING AN EXPERIMENTAL MODEL OF EQUINE OSTEOARTHRITIS
Anderson, J., Jenkins, R., Welting, T., Green, D., Johnson, E., Jocobsen, S., & Peffers, M. J. (2023). TEMPORAL PROTEOMIC LANDSCAPE OF PLASMA AND SYNOVIAL FLUID DERIVED EXTRACELLULAR VESICLES USING AN EXPERIMENTAL MODEL OF EQUINE OSTEOARTHRITIS. OSTEOARTHRITIS AND CARTILAGE, 31, S345. Retrieved from https://www.webofscience.com/
THE BIOLOGICAL RESPONSE OF ANTERIOR CRUCIATE LIGAMENTOCYTES FOLLOWING TREATMENT WITH SYNOVIAL FLUID EXTRACELLULAR VESICLES
Cookson, D., Comerford, E., Anderson, J., Peffers, M., & Kharaz, Y. A. (2023). THE BIOLOGICAL RESPONSE OF ANTERIOR CRUCIATE LIGAMENTOCYTES FOLLOWING TREATMENT WITH SYNOVIAL FLUID EXTRACELLULAR VESICLES. OSTEOARTHRITIS AND CARTILAGE, 31, S35. Retrieved from https://www.webofscience.com/
The biological response of canine cruciate ligamentocytes following treatment with synovial fluid extracellular vesicles
Cookson, D., Kharaz, Y. A., Anderson, J., Peffers, M., & Comerford, E. (2023). The biological response of canine cruciate ligamentocytes following treatment with synovial fluid extracellular vesicles. In BSAVA Congress Proceedings 2023. British Small Animal Veterinary Association. doi:10.22233/9781913859152.38.3
Editorial: Epigenetic regulation of the musculoskeletal system in health, disease, and aging
Goljanek-Whysall, K., Tew, S., Peffers, M. J., & Kanakis, I. (2023). Editorial: Epigenetic regulation of the musculoskeletal system in health, disease, and aging. FRONTIERS IN ENDOCRINOLOGY, 14. doi:10.3389/fendo.2023.1143210
Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3
Direct comparison of non-osteoarthritic and osteoarthritic synovial fluid-induced intracellular chondrocyte signaling and phenotype changes
Housmans, B. A. C., van den Akker, G. G. H., Neefjes, M., Timur, U. T., Cremers, A., Peffers, M. J., . . . Welting, T. J. M. (2023). Direct comparison of non-osteoarthritic and osteoarthritic synovial fluid-induced intracellular chondrocyte signaling and phenotype changes. OSTEOARTHRITIS AND CARTILAGE, 31(1), 60-71. doi:10.1016/j.joca.2022.09.004
Extracellular vesicle microRNA crosstalk between chondrocytes and sysnoviocytes- an in vitro approach
Peffers, M. J., Castanheira, C. I., Anderson, J. R., Hackl, M., Clarke, E. J., James, V., & Clegg, P. D. (2023). Extracellular vesicle microRNA crosstalk between chondrocytes and sysnoviocytes- an in vitro approach. In TISSUE ENGINEERING PART A Vol. 29. Retrieved from https://www.webofscience.com/
The effect of maternal and early-life nutrition on redox homeostasis
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3
2022
Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis
Baker, M. E. E., Lee, S., Clinton, M., Hackl, M., Castanheira, C., Peffers, M. J. J., & Taylor, S. E. E. (2022). Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(24). doi:10.3390/ijms232415526
Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis.
Clarke, E. J., Johnson, E., Caamaño Gutierrez, E., Andersen, C., Berg, L. C., Jenkins, R. E., . . . Peffers, M. J. (2022). Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis.. Frontiers in veterinary science, 9, 1057667. doi:10.3389/fvets.2022.1057667
Advances in the pharmaceutical treatment options for canine osteoarthritis
Pye, C., Bruniges, N., Peffers, M., & Comerford, E. (2022). Advances in the pharmaceutical treatment options for canine osteoarthritis. JOURNAL OF SMALL ANIMAL PRACTICE, 63(10), 721-738. doi:10.1111/jsap.13495
The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence
Wijesinghe, S. N., Anderson, J., Brown, T. J., Nanus, D. E., Housmans, B., Green, J. A., . . . Peffers, M. J. (2022). The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence. In FRONTIERS IN MOLECULAR BIOSCIENCES Vol. 9. doi:10.3389/fmolb.2022.971621
The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence
Peffers, M. (2022). The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2022.971621
Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls
Clarke, E. J., Lima, C., Anderson, J. R., Castanheira, C., Beckett, A., James, V., . . . Peffers, M. J. (2022). Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls. ANALYTICAL METHODS. doi:10.1039/d2ay00779g
Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament disease
Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis
Anderson, J. R., Jacobsen, S., Walters, M., Bundgaard, L., Diendorfer, A., Hackl, M., . . . Peffers, M. J. (n.d.). Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis. Frontiers in Veterinary Science, 9. doi:10.3389/fvets.2022.901269
Adaptation of the protein translational apparatus during ATDC5 chondrogenic differentiation
Steinbusch, M. M. F., van den Akker, G. G. H., Cremers, A., Witlox, A. M. A., Staal, H. M., Peffers, M. J., . . . Welting, T. J. M. (2022). Adaptation of the protein translational apparatus during ATDC5 chondrogenic differentiation. NON-CODING RNA RESEARCH, 7(2), 55-65. doi:10.1016/j.ncrna.2022.02.003
Differences in the metabolomic profile of canine stifle joint synovial fluid in dogs with cranial cruciate ligament rupture with or without meniscal injury
Pye, C., Phelan, M., Green, D., Comerford, E., & Peffers, M. (2022). Differences in the metabolomic profile of canine stifle joint synovial fluid in dogs with cranial cruciate ligament rupture with or without meniscal injury. In BSAVA Congress Proceedings 2022. British Small Animal Veterinary Association. doi:10.22233/9781913859114.32.2
Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era
Jahangir, S., John, P., Bhatti, A., Aslam, M. M., & Peffers, M. J. (2022). Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era. In 2022 2nd International Conference on Advance Computing and Innovative Technologies in Engineering (ICACITE) (pp. 956-964). IEEE. doi:10.1109/icacite53722.2022.9823601
Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated Network
Shorter, E., Avelar, R., Zachariou, M., Spyrou, G. M., Raina, P., Smagul, A., . . . Poulet, B. (n.d.). Identifying Novel Osteoarthritis-Associated Genes in Human Cartilage Using a Systematic Meta-Analysis and a Multi-Source Integrated Network. International Journal of Molecular Sciences, 23(8), 4395. doi:10.3390/ijms23084395
BCP CRYSTALS IN OSTEOARTHRITIS; UNRAVELLING THE CHANGING CHONDROCYTE SECRETOME
Stassen, R., van den Akker, G., Surtel, D., Cremers, A., Peffers, M., van Rhijn, L., & Welting, T. (2022). BCP CRYSTALS IN OSTEOARTHRITIS; UNRAVELLING THE CHANGING CHONDROCYTE SECRETOME. Osteoarthritis and Cartilage, 30, S26. doi:10.1016/j.joca.2022.02.023
DYNAMIC RIBOSOMES IN OSTEOARTHRITIS
Chabronova, A., van den Akker, G. G., Housmans, B. A., Caron, M. M., Cremers, A., Surtel, D. A., . . . Welting, T. J. (2022). DYNAMIC RIBOSOMES IN OSTEOARTHRITIS. Osteoarthritis and Cartilage, 30, S348-S350. doi:10.1016/j.joca.2022.02.469
NOVEL SPECTROSCOPY TECHNIQUES USED TO INTERROGATE EQUINE OSTEOARTHRITIC EXTRACELLULAR VESICLES
Clarke, E. J., Lima, C., Anderson, J. R., Castanheira, C., Hyett, J., Goodacre, R., & Peffers, M. J. (2022). NOVEL SPECTROSCOPY TECHNIQUES USED TO INTERROGATE EQUINE OSTEOARTHRITIC EXTRACELLULAR VESICLES. OSTEOARTHRITIS AND CARTILAGE, 30, S95-S96. Retrieved from https://www.webofscience.com/
SYNOVIAL FLUID SNORNAS METANALYSIS IN EQUINE OSTEOARTHRITIS
Regardh, S., Jacobsen, S., Bundgaard, L., Walters, M., Anderson, J., Castanheira, C., & Peffers, M. J. (2022). SYNOVIAL FLUID SNORNAS METANALYSIS IN EQUINE OSTEOARTHRITIS. OSTEOARTHRITIS AND CARTILAGE, 30, S351. Retrieved from https://www.webofscience.com/
TRANSCRIPTOMIC EXPRESSION COMPARISON BETWEEN THE MEDIAL AND LATERAL FEMORAL CARTILAGE OF SHEEP
Hontoir, F., Peffers, M. J., Welting, T., Steijns, J., Simon, V., & Vandeweerd, J. -M. (2022). TRANSCRIPTOMIC EXPRESSION COMPARISON BETWEEN THE MEDIAL AND LATERAL FEMORAL CARTILAGE OF SHEEP. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S344-S345). Retrieved from https://www.webofscience.com/
USE OF A 3′ RNA SEQUENCING APPROACH TO DETERMINE DIFFERENTIAL TRANSCRIPT EXPRESSION AND ALTERNATIVE POLYADENYLATION SITE USAGE BETWEEN AGE MATCHED, HEALTHY AND OSTEOARTHRITIC KNEE CARTILAGE
Winstanley-Zarach, P., Kuba, S., Smagul, A., Peffers, M. J., Rot, G., & Tew, S. R. (2022). USE OF A 3′ RNA SEQUENCING APPROACH TO DETERMINE DIFFERENTIAL TRANSCRIPT EXPRESSION AND ALTERNATIVE POLYADENYLATION SITE USAGE BETWEEN AGE MATCHED, HEALTHY AND OSTEOARTHRITIC KNEE CARTILAGE. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S351-S352). Retrieved from https://www.webofscience.com/
LC-MS/MS-Based Serum Protein Profiling for Identification of Candidate Biomarkers in Pakistani Rheumatoid Arthritis Patients
Jahangir, S., John, P., Bhatti, A., Aslam, M. M., Mehmood Malik, J., Anderson, J. R., & Peffers, M. J. (n.d.). LC-MS/MS-Based Serum Protein Profiling for Identification of Candidate Biomarkers in Pakistani Rheumatoid Arthritis Patients. Life, 12(3), 464. doi:10.3390/life12030464
Open Research-What is it, and how can <i>Equine Veterinary Journal's</i> authors engage with Open Research initiatives?
Peffers, M. J., & Webster, L. C. (2022). Open Research-What is it, and how can <i>Equine Veterinary Journal's</i> authors engage with Open Research initiatives?. EQUINE VETERINARY JOURNAL, 54(2), 197-200. doi:10.1111/evj.13546
Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study
Guitart-Mampel, M., Urquiza, P., Carnevale Neto, F., Anderson, J. R., Hambardikar, V., Scoma, E. R., . . . Solesio, M. E. (n.d.). Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study. Frontiers in Cell and Developmental Biology, 10. doi:10.3389/fcell.2022.833127
A systems biology approach to study the dysregulation of type I collagen during ageing and disease
Johnson, E. (2022). A systems biology approach to study the dysregulation of type I collagen during ageing and disease.
DYNAMIC RIBOSOMES IN OSTEOARTHRITIS
Chabronova, A., van den Akker, G. G., Housmans, B. A., Caron, M. M., Cremers, A., Surtel, D. A., . . . Welting, T. J. (2022). DYNAMIC RIBOSOMES IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 30 (pp. S349-S350). Retrieved from https://www.webofscience.com/
Ribosome dysfunction in osteoarthritis
van den Akker, G. G. H., Caron, M. M. J., Peffers, M. J., & Welting, T. J. M. (2022). Ribosome dysfunction in osteoarthritis. CURRENT OPINION IN RHEUMATOLOGY, 34(1), 61-67. doi:10.1097/BOR.0000000000000858
SOX9 DETERMINES TRANSLATIONAL CAPACITY DURING EARLY CHONDROGENIC DIFFERENTIATION OF ATDC5 CELLS BY REGULATING EXPRESSION OF RIBOSOME BIOGENESIS FACTORS AND RIBOSOMAL PROTEINS
Caron, M. M. J., Eveque, M., Cillero-Pastor, B., Heeren, R. M. A., Housmans, B., Derks, K., . . . Welting, T. J. M. (2022). SOX9 DETERMINES TRANSLATIONAL CAPACITY DURING EARLY CHONDROGENIC DIFFERENTIATION OF ATDC5 CELLS BY REGULATING EXPRESSION OF RIBOSOME BIOGENESIS FACTORS AND RIBOSOMAL PROTEINS. In TISSUE ENGINEERING PART A Vol. 28 (pp. S385-S386). Retrieved from https://www.webofscience.com/
2021
Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts
Chabronova, A., van den Akker, G. G. H., Meekels-Steinbusch, M. M. F., Friedrich, F., Cremers, A., Surtel, D. A. M., . . . Welting, T. J. M. (2021). Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts. NON-CODING RNA RESEARCH, 6(4), 211-224. doi:10.1016/j.ncrna.2021.12.003
A Network Biology Approach to Understanding the Tissue-Specific Roles of Non-Coding RNAs in Arthritis
Ali, S. A., Pastrello, C., Kaur, N., Peffers, M. J., Ormseth, M. J., & Jurisica, I. (2021). A Network Biology Approach to Understanding the Tissue-Specific Roles of Non-Coding RNAs in Arthritis. FRONTIERS IN ENDOCRINOLOGY, 12. doi:10.3389/fendo.2021.744747
An Evaluation of Current Preventative Measures Used in Equine Practice to Maintain Distal Forelimb Functionality: A Mini Review
Clarke, E. J., Gillen, A., Turlo, A., & Peffers, M. J. (2021). An Evaluation of Current Preventative Measures Used in Equine Practice to Maintain Distal Forelimb Functionality: A Mini Review. FRONTIERS IN VETERINARY SCIENCE, 8. doi:10.3389/fvets.2021.758970
The non-coding RNA interactome in joint health and disease
Ali, S. A., Peffers, M. J., Ormseth, M. J., Jurisica, I., & Kapoor, M. (2021). The non-coding RNA interactome in joint health and disease. Nature Reviews Rheumatology. doi:10.1038/s41584-021-00687-y
CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4
Marr, N., Meeson, R., Kelly, E. F., Fang, Y., Peffers, M. J., Pitsillides, A. A., . . . Thorpe, C. T. (2021). CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(18). doi:10.3390/ijms22189729
Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins
Caron, M. M. J., Eveque, M., Cillero-Pastor, B., Heeren, R. M. A., Housmans, B., Derks, K., . . . Welting, T. J. M. (2021). Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9. doi:10.3389/fcell.2021.686096
Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis
Castanheira, C. I. G. D., Anderson, J. R., Fang, Y., Milner, P. I., Goljanek-Whysall, K., House, L., . . . Peffers, M. J. (2021). Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis. Osteoarthritis and Cartilage Open, 100186. doi:10.1016/j.ocarto.2021.100186
Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S. E., . . . Vasilaki, A. (2021). Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation. CELLS, 10(5). doi:10.3390/cells10051166
Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy
Hulme, C. H., Peffers, M. J., Harrington, G. M. B., Wilson, E., Perry, J., Roberts, S., . . . Wright, K. T. (2021). Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome After Microfracture or Osteotomy. AMERICAN JOURNAL OF SPORTS MEDICINE, 49(6), 1512-1523. doi:10.1177/0363546521995565
CHANGES IN SMALL NON-CODING RNA EXPRESSION IN SYNOVIAL FLUID DURING DISEASE PROGRESSION IN AN EQUINE MODEL OF EXPERIMENTAL OSTEOARTHRITIS
Walters, M., Skovgaard, K., Heegaard, P., Peffers, M., Fang, Y., Bundgaard, L., . . . Jacobsen, S. (2021). CHANGES IN SMALL NON-CODING RNA EXPRESSION IN SYNOVIAL FLUID DURING DISEASE PROGRESSION IN AN EQUINE MODEL OF EXPERIMENTAL OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S155-S156). Retrieved from https://www.webofscience.com/
EPIGENETIC CHANGES IN AGEING HUMAN TENDON TISSUE
Riasat, K., Cockell, S. J., Green, D. C., Pease, L. I., & Peffers, M. J. (2021). EPIGENETIC CHANGES IN AGEING HUMAN TENDON TISSUE. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S309-S310). Retrieved from https://www.webofscience.com/
SYNOVIAL FLUID AND SERUM SMALL NON-CODING RNA SIGNATURES IN EQUINE OSTEOARTHRITIS
Castanheira, C., James, V., Taylor, S., Skioldebrand, E., Clegg, P. D., & Peffers, M. J. (2021). SYNOVIAL FLUID AND SERUM SMALL NON-CODING RNA SIGNATURES IN EQUINE OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S162). Retrieved from https://www.webofscience.com/
TNF-ALPHA INDUCES FGF1 IRES MEDIATED MESSENGER RNA TRANSLATION IN CHONDROCYTES
van den Akker, G. G., Chabronova, A., Housmans, B. A., Surtel, D., Cremers, A., Peffers, M., . . . Welting, T. J. (2021). TNF-ALPHA INDUCES FGF1 IRES MEDIATED MESSENGER RNA TRANSLATION IN CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S50-S51). Retrieved from https://www.webofscience.com/
Nuclear magnetic resonance spectroscopy of biofluids for osteoarthritis
Clarke, E. J., Anderson, J. R., & Peffers, M. J. (2021). Nuclear magnetic resonance spectroscopy of biofluids for osteoarthritis. BRITISH MEDICAL BULLETIN, 137(1), 28-41. doi:10.1093/bmb/ldaa037
Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S., . . . Vasilaki, A. (2021). Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation. doi:10.1101/2021.02.22.432208
Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
Castanheira, C., Balaskas, P., Falls, C., Ashraf-Kharaz, Y., Clegg, P., Burke, K., . . . Peffers, M. J. (2021). Equine synovial fluid small non-coding RNA signatures in early osteoarthritis. BMC VETERINARY RESEARCH, 17(1). doi:10.1186/s12917-020-02707-7
1H NMR Lipidomic Analysis of Canine Stifle Joint Synovial Fluid to Detect Biomarkers of Medial Meniscal Injury
Burke, C., Anderson, J. R., Clarke, E. J., Phelan, M. M., Comerford, E. J., & Peffers, M. J. (2021). 1H NMR Lipidomic Analysis of Canine Stifle Joint Synovial Fluid to Detect Biomarkers of Medial Meniscal Injury. British Small Animal Veterinary Association. doi:10.22233/9781913859039.19
Identification of tissue-dependent proteins in knee OA synovial fluid
Timur, U. T., Jahr, H., Anderson, J., Green, D. C., Emans, P. J., Smagul, A., . . . Welting, T. J. M. (2021). Identification of tissue-dependent proteins in knee OA synovial fluid. OSTEOARTHRITIS AND CARTILAGE, 29(1), 124-133. doi:10.1016/j.joca.2020.09.005
Small Nucleolar RNA Expression Profiling in Cartilage
Peffers, M. J., Cremers, A., & Welting, T. J. M. (2021). Small Nucleolar RNA Expression Profiling in Cartilage. In CHONDROCYTES (Vol. 2245, pp. 135-149). doi:10.1007/978-1-0716-1119-7_10
microRNA:target interactions in tendinopathy
Bardell, D. A. (2021). microRNA:target interactions in tendinopathy.
2020
SnoRNA signatures in cartilage ageing and osteoarthritis
Peffers, M. J., Chabronova, A., Balaskas, P., Fang, Y., Dyer, P., Cremers, A., . . . Welting, T. J. M. (2020). SnoRNA signatures in cartilage ageing and osteoarthritis. In SCIENTIFIC REPORTS Vol. 10. doi:10.1038/s41598-020-67446-z
Epigenetic mechanisms in tendon ageing
Riasat, K., Bardell, D., Goljanek-Whysall, K., Clegg, P., & Peffers, M. (n.d.). Epigenetic mechanisms in tendon ageing. British Medical Bulletin. doi:10.1093/bmb/ldaa023
The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach
Mennan, C., Hopkins, T., Channon, A., Elliott, M., Johnstone, B., Kadir, T., . . . Roberts, S. (2020). The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach. Osteoarthritis and Cartilage Open, 100081. doi:10.1016/j.ocarto.2020.100081
Impaired chondrocyte U3 snoRNA expression in osteoarthritis impacts the chondrocyte protein translation apparatus
Peffers, M. (2020). Impaired chondrocyte U3 snoRNA expression in osteoarthritis impacts the chondrocyte protein translation apparatus. Scientific Reports, 10. doi:10.1038/s41598-020-70453-9
Small Non-Coding RNAome of Ageing Chondrocytes
Balaskas, P., Green, J. A., Haqqi, T. M., Dyer, P., Kharaz, Y. A., Fang, Y., . . . Peffers, M. J. (2020). Small Non-Coding RNAome of Ageing Chondrocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(16). doi:10.3390/ijms21165675
Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study.
Anderson, J. R., Phelan, M. M., Foddy, L., Clegg, P. D., & Peffers, M. J. (2020). Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study.. Journal of proteome research. doi:10.1021/acs.jproteome.0c00143
Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics
Anderson, J. R., Phelan, M. M., Rubio-Martinez, L. M., Fitzgerald, M. M., Jones, S. W., Clegg, P. D., & Peffers, M. J. (2020). Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics. Journal of Proteome Research, 19(7), 2585-2597. doi:10.1021/acs.jproteome.0c00035
SnoRNA signatures in cartilage ageing and osteoarthritis.
Peffers, M. J., Chabronova, A., Balaskas, P., Fang, Y., Dyer, P., Cremers, A., . . . Welting, T. J. M. (2020). SnoRNA signatures in cartilage ageing and osteoarthritis.. Scientific Reports, 10. doi:10.1038/s41598-020-67446-z
Small Non-coding RNAome of ageing chondrocytes
Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis
Kharaz, Y., Fang, Y., Welting, T., Peffers, M., & Comerford, E. (2020). Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis. doi:10.1101/2020.05.14.20101048
Metabolomic and Proteomic Stratification of Equine Osteoarthritis
Anderson, J., Phelan, M., Caamaño-Gutiérrez, E., Clegg, P., Rubio-Martinez, L., & Peffers, M. (2020). Metabolomic and Proteomic Stratification of Equine Osteoarthritis. doi:10.1101/2020.05.04.077305
Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
Castanheira, C., Balaskas, P., Falls, C., Ashraf-Kharaz, Y., Clegg, P., Burke, K., . . . Peffers, M. (2020). Equine synovial fluid small non-coding RNA signatures in early osteoarthritis. doi:10.1101/2020.05.01.066027
SnoRNA signatures in cartilage ageing and osteoarthritis
IMPAIRED CHONDRCOYTE U3 SNORNA EXPRESSION IN OSTEOARTHRITIS AND ITS IMPACT ON THE CHONDROCYTE'S PROTEIN TRANSLATION APPARATUS
Ripmeester, E. G., Caron, M. M., Balaskas, P., Dyer, P., Chabronova, A., van den Akker, G. G., . . . Welting, T. J. (2020). IMPAIRED CHONDRCOYTE U3 SNORNA EXPRESSION IN OSTEOARTHRITIS AND ITS IMPACT ON THE CHONDROCYTE'S PROTEIN TRANSLATION APPARATUS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S47). Retrieved from https://www.webofscience.com/
SMALL NON-CODING RNA SIGNATURES IN CARTILAGE AGEING
Peffers, M. J., Balaskas, P., Fang, Y., Green, J. A., Haqqi, T. M., & Welting, T. J. (2020). SMALL NON-CODING RNA SIGNATURES IN CARTILAGE AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S347-S348). Retrieved from https://www.webofscience.com/
SMALL NON-CODING RNA SIGNATURES OF HEALTHY AND DISEASED ANTERIOR CRUCIATE LIGAMENT
Kharaz, Y. A., Peffers, M., Fang, Y., Welting, T., & Comerford, E. (2020). SMALL NON-CODING RNA SIGNATURES OF HEALTHY AND DISEASED ANTERIOR CRUCIATE LIGAMENT. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S198-S199). Retrieved from https://www.webofscience.com/
SMALL NUCLEOLAR RNAS AS MEDIATORS OF OXIDATIVE STRESS IN CROSS SPECIES CARTILAGE AND OSTEOARTHRITIS
Pimlott, Z., Hontoir, F., Kharaz, Y. A., Anderson, J., Dyer, P., Collins, J., . . . Peffers, M. J. (2020). SMALL NUCLEOLAR RNAS AS MEDIATORS OF OXIDATIVE STRESS IN CROSS SPECIES CARTILAGE AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S342). Retrieved from https://www.webofscience.com/
TGF-BETA INDUCES RIBOSOME ACTIVITY, ALTERS RIBOSOME COMPOSITION AND INHIBITS IRES-MEDIATED TRANSLATION IN CHONDROCYTES
van den Akker, G. G., Surtel, D. A., Chabronova, A., Housmans, B. A., Caron, M. M., Peffers, M. J., & Welting, T. J. (2020). TGF-BETA INDUCES RIBOSOME ACTIVITY, ALTERS RIBOSOME COMPOSITION AND INHIBITS IRES-MEDIATED TRANSLATION IN CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S348-S349). Retrieved from https://www.webofscience.com/
THE ROLE OF SNORD116 IN CARTILAGE AGEING AND OSTEOARTHRITIS
Peffers, M. J., Dale, A. G., Clough, H., Dyer, P., Ellis, J., Tew, S., . . . Welting, T. (2020). THE ROLE OF SNORD116 IN CARTILAGE AGEING AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 28 (pp. S342-S343). Retrieved from https://www.webofscience.com/
Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Anderson, J., Phelan, M., Foddy, L., Clegg, P., & Peffers, M. (2020). <i>Ex-Vivo</i>Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study. doi:10.1101/2020.03.03.974501
2019
Translational regulation contributes to the secretory response of chondrocytic cells following exposure to Interleukin-1β
Mcdermott, B., Peffers, M., McDonagh, B., & Tew, S. R. (2019). Translational regulation contributes to the secretory response of chondrocytic cells following exposure to Interleukin-1β. Journal of Biological Chemistry, 294(35), 13027-13029. doi:10.1074/jbc.RA118.006865
Defining the role and mechanism of microRNAs in osteoarthritis
Balaskas, P., Whysall, K., Clegg, P., Welting, T., & Peffers, M. (2019). Defining the role and mechanism of microRNAs in osteoarthritis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A10). Retrieved from https://www.webofscience.com/
The synovial fluid proteome differentiates between septic and nonseptic articular pathologies
Anderson, J. R., Smagul, A., Simpson, D., Clegg, P. D., Rubio-Martinez, L. M., & Peffers, M. J. (2019). The synovial fluid proteome differentiates between septic and nonseptic articular pathologies. JOURNAL OF PROTEOMICS, 202. doi:10.1016/j.jprot.2019.04.020
Proteomic analysis of synovial fluid: current and potential uses to improve clinical outcomes.
Peffers, M. J., Smagul, A., & Anderson, J. R. (2019). Proteomic analysis of synovial fluid: current and potential uses to improve clinical outcomes. EXPERT REVIEW OF PROTEOMICS, 16(4), 287-302. doi:10.1080/14789450.2019.1578214
COMPARISON MICRORNAS EXPRESSION IN NORMAL AND RUPTURED CANINE CRUCIATE LIGAMENTS
Kharaz, Y. A., Peffers, M., & Comerford, E. (2019). COMPARISON MICRORNAS EXPRESSION IN NORMAL AND RUPTURED CANINE CRUCIATE LIGAMENTS. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S477). doi:10.1016/j.joca.2019.02.524
THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS
Caron, M. M., Derks, K., Sanderink, L., van Rhijn, L., Peffers, M., & Welting, T. (2019). THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S196). doi:10.1016/j.joca.2019.02.303
The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion.
Steinbusch, M. M. F., Caron, M. M. J., Surtel, D. A. M., van den Akker, G. G. H., van Dijk, P. J., Friedrich, F., . . . Welting, T. J. M. (2019). The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion.. The Journal of Biological Chemistry, 294(13), 5121-5136. doi:10.1074/jbc.ra119.007356
Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to diagnose osteoarthritis in equine serum.
Paraskevaidi, M., Hook, P. D., Morais, C. L. M., Anderson, J. R., White, R., Martin-Hirsch, P. L., . . . Martin, F. L. (2019). Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to diagnose osteoarthritis in equine serum.. Equine veterinary journal. doi:10.1111/evj.13115
Differences in plasma and peritoneal fluid proteomes identifies potential biomarkers associated with survival following strangulating small intestinal disease
Bardell, D. A., Milner, P., Whysall, K., & Peffers, M. (2019). Differences in plasma and peritoneal fluid proteomes identifies potential biomarkers associated with survival following strangulating small intestinal disease. Equine Veterinary Journal. doi:10.1111/evj.13094
Osteoarthritis year in review 2018: genetics and epigenetics.
Jeffries, M. A. (2019). Osteoarthritis year in review 2018: genetics and epigenetics.. Osteoarthritis and cartilage, 27(3), 371-377. doi:10.1016/j.joca.2018.10.004
The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion
Peffers, M. J. (2019). The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion. Journal of Biological Chemistry. doi:10.1074/jbc.RA119.007356
A metabolic approach towards optimising equine in vitro maturation
Lewis, N. L. (2019). A metabolic approach towards optimising equine in vitro maturation.
Comparison of RNA extraction methods in equine synovial fluid in the determination of the expression of small non-coding RNAs
Kharaz, Y. A., Comerford, E., & Peffers, M. (2019). Comparison of RNA extraction methods in equine synovial fluid in the determination of the expression of small non-coding RNAs. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A23). Retrieved from https://www.webofscience.com/
Proteomic and metabolomic signatures of arthropathies
Anderson, J. R. (2019). Proteomic and metabolomic signatures of arthropathies.
Small non-coding RNA transcriptome signatures of chondrocyte ageing
Peffers, M. J., Smaghul, A., Balaska, P., Fang, Y., & Welting, S. T. M. (2019). Small non-coding RNA transcriptome signatures of chondrocyte ageing. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A30). Retrieved from https://www.webofscience.com/
The articular cartilage proteome is dependent on zone, age and disease state
Smagul, A., Simpson, D., Tew, S., & Peffers, M. J. (2019). The articular cartilage proteome is dependent on zone, age and disease state. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A36). Retrieved from https://www.webofscience.com/
Understanding the role of HACD enzymes and very long chain fatty acids in muscle development and disease
Morgan, R. S. (2019). Understanding the role of HACD enzymes and very long chain fatty acids in muscle development and disease.
2018
Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs)
Hulme, C. H., Wilson, E., Fuller, H. R., Roberts, S., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). Identification of synovial fluid proteins that are associated with early osteoarthritis treatment failure: the search for novel markers leads us back to matrix metalloproteinases (MMPs). In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A2). Retrieved from https://www.webofscience.com/
Insulin-like growth factor binding protein (Igfbp6) is a cross-species transcriptomic tendon marker
Mueller-Breckenridge, A. J., Turlo, A. J., Zamboulis, D., Peffers, M. J., & Clegg, P. D. (2018). Insulin-like growth factor binding protein (Igfbp6) is a cross-species transcriptomic tendon marker. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A2-A3). Retrieved from https://www.webofscience.com/
1H NMR metabolomics identifies underlying inflammatory pathology in osteoarthritis and rheumatoid arthritis synovial joints
Anderson, J., Chokesuwattanaskul, S., Phelan, M., Welting, T., Lian, L. Y., Peffers, M., & Wright, H. L. (2018). 1H NMR metabolomics identifies underlying inflammatory pathology in osteoarthritis and rheumatoid arthritis synovial joints. Journal of Proteome Research, 17(11), 3780-3790. doi:10.1021/acs.jproteome.8b00455
Towards a toolkit for the assessment and monitoring of musculoskeletal ageing
Kemp, G. J., Jackson, M. J., Mccloskey, E. V., & Mathers, J. C. (2018). Towards a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(6), 774-777. doi:10.1093/ageing/afy078
Developing a toolkit for the assessment and monitoring of musculoskeletal ageing
Kemp, G. J., Birrell, F., Clegg, P. D., Cuthbertson, D. J., De Vito, G., van Dieen, J. H., . . . Mathers, J. C. (2018). Developing a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47(suppl_4), iv1-iv19. doi:10.1093/ageing/afy143
Stratifying osteoarthritis using liquid chromatography‐tandem mass spectrometry proteomic analysis of synovial fluid
Stratifying osteoarthritis using liquid chromatography‐tandem mass spectrometry proteomic analysis of synovial fluid (2018). In Equine Veterinary Journal Vol. 50 (pp. 26-27). Wiley. doi:10.1111/evj.48_13008
Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies
Anderson, J. R., Phelan, M. M., Clegg, P. D., Peffers, M. J., & Rubio-Martinez, L. M. (2018). Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies. Journal of Proteome Research, 17(8), 2735-2743. doi:10.1021/acs.jproteome.8b00190
Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation
Hulme, C. H., Wilson, E. L., Fuller, H. R., Roberts, S., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation. ARTHRITIS RESEARCH & THERAPY, 20. doi:10.1186/s13075-018-1573-4
251 Synovial fluid metabolite profiles differ between osteoarthritis and rheumatoid arthritis
Anderson, J. R., Chokesuwattanaskul, S., Phelan, M. P., Welting, T. J. M., Lian, L. -Y., Peffers, M. J., & Wright, H. L. (2018). 251 Synovial fluid metabolite profiles differ between osteoarthritis and rheumatoid arthritis. Rheumatology, 57(suppl_3). doi:10.1093/rheumatology/key075.475
A ROLE FOR SMALL NUCLEOLAR RNA HOST GENES IN CARTILAGE AGEING AND OSTEOARTHRITIS
Peffers, M. J., Balaska, P., Dyers, P., Welting, T., & Cremers, A. (2018). A ROLE FOR SMALL NUCLEOLAR RNA HOST GENES IN CARTILAGE AGEING AND OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S160-S161). doi:10.1016/j.joca.2018.02.349
A ROLE FOR THE SNORNA U3 IN THE ALTERED TRANSLATIONAL CAPACITY OF AGEING AND OSTEOARTHRITIC CHONDROCYTES
Peffers, M. J., Ripmeester, E., Caron, M., Steinbusch, M., Balaskas, P., Cremers, A., . . . Welting, T. J. (2018). A ROLE FOR THE SNORNA U3 IN THE ALTERED TRANSLATIONAL CAPACITY OF AGEING AND OSTEOARTHRITIC CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S45-S46). doi:10.1016/j.joca.2018.02.106
ACUTE PHASE RESPONSE SIGNALLING IS ALTERED FOLLOWING CARTILAGE HARVEST IN NON-RESPONDERS TO AUTOLOGOUS CHONDROCYTE IMPLANTATION
Hulme, C. H., Wilson, E. L., Fuller, H. R., Roberts, S. R., Richardson, J. B., Gallacher, P., . . . Wright, K. T. (2018). ACUTE PHASE RESPONSE SIGNALLING IS ALTERED FOLLOWING CARTILAGE HARVEST IN NON-RESPONDERS TO AUTOLOGOUS CHONDROCYTE IMPLANTATION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S167). doi:10.1016/j.joca.2018.02.363
COMPREHENSIVE EXPRESSION ANALYSIS OF SMALL NON CODING RNAS IN EARLY OSTEOARTHRITIS SYNOVIAL FLUID
Peffers, M. J., Balaska, P., Fang, Y., Anderson, J., Burke, K., & Welting, T. (2018). COMPREHENSIVE EXPRESSION ANALYSIS OF SMALL NON CODING RNAS IN EARLY OSTEOARTHRITIS SYNOVIAL FLUID. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S186-S187). doi:10.1016/j.joca.2018.02.401
DEFINING THE ROLE AND MECHANISMS OF MICRORNAS IN CARTILAGE AGEING AND DISEASE
Balaskas, P., Goljanek-Whysall, K., Clegg, P., Welting, T., & Peffers, M. (2018). DEFINING THE ROLE AND MECHANISMS OF MICRORNAS IN CARTILAGE AGEING AND DISEASE. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165). doi:10.1016/j.joca.2018.02.360
IDENTIFICATION OF TISSUE-SPECIFIC BIOMARKERS IN KNEE OSTEOARTHRITIS SYNOVIAL FLUID: A PROTEOMIC APPROACH
Timur, U., Jahr, H., Emans, P., van Rhijn, L., Peffers, M., & Welting, T. (2018). IDENTIFICATION OF TISSUE-SPECIFIC BIOMARKERS IN KNEE OSTEOARTHRITIS SYNOVIAL FLUID: A PROTEOMIC APPROACH. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S42). doi:10.1016/j.joca.2018.02.100
Proteomic analysis of equine plasma and peritoneal fluid in strangulating small intestinal disease
Bardell, D. A., Peffers, M. J., & Milner, P. I. (n.d.). Proteomic analysis of equine plasma and peritoneal fluid in strangulating small intestinal disease. The FASEB Journal.
RIBOSOMAL PROFILING AND SECRETOME ANALYSIS IDENTIFY THAT INTERLEUKIN-1B DRIVEN CYTOKINE/CHEMOKINE RELEASE FROM CHONDROCYTIC CELLS IS UNDERPINNED BY DIFFERENTIAL TRANSLATION
McDermott, B. T., Peffers, M. J., McDonagh, B., & Tew, S. R. (2018). RIBOSOMAL PROFILING AND SECRETOME ANALYSIS IDENTIFY THAT INTERLEUKIN-1B DRIVEN CYTOKINE/CHEMOKINE RELEASE FROM CHONDROCYTIC CELLS IS UNDERPINNED BY DIFFERENTIAL TRANSLATION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S105). doi:10.1016/j.joca.2018.02.228
STRATIFYING OSTEOARTHRITIS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY PROTEOMIC ANALYSIS OF SYNOVIAL FLUID
Anderson, J. R., Clegg, P. D., Rubio-Martinez, L. M., Riggs, C. M., & Peffers, M. J. (2018). STRATIFYING OSTEOARTHRITIS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY PROTEOMIC ANALYSIS OF SYNOVIAL FLUID. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S171). doi:10.1016/j.joca.2018.02.372
THE EFFECT OF U3 SNORNA KNOCKDOWN ON THE CHONDROCYTE PROTEOME
Smagul, A., Tew, S., & Peffers, M. J. (2018). THE EFFECT OF U3 SNORNA KNOCKDOWN ON THE CHONDROCYTE PROTEOME. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165). doi:10.1016/j.joca.2018.02.359
THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS
Caron, M. M., Derks, K. W., Sanderink, L., van Rhijn, L. W., Peffers, M. J., & Welting, T. J. (2018). THE GATE TO CONTROLLING CHONDROGENIC DIFFERENTIATION: TRANSCRIPTIONAL REGULATION BY SOX9 IN ATDC5 CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S109). doi:10.1016/j.joca.2018.02.238
THE ROLE OF MICRORNAS IN TENDON DYSFUNCTION
Bardell, D., Peffers, M. J., Clegg, P. D., Molloy, A. P., & Goljanek-Whysall, K. (2018). THE ROLE OF MICRORNAS IN TENDON DYSFUNCTION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S165-S166). doi:10.1016/j.joca.2018.02.361
VIPERIN REGULATES CHONDROGENIC DIFFERENTIATION VIA CXCL10 PROTEIN SECRETION
Steinbusch, M. M., Caroni, M. M., Surtel, D. A., van Dijk, P. J., Friedrich, F., Zabel, B., . . . Welting, T. J. (2018). VIPERIN REGULATES CHONDROGENIC DIFFERENTIATION VIA CXCL10 PROTEIN SECRETION. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S93). doi:10.1016/j.joca.2018.02.200
Effects of stanozolol on normal and IL-1β-stimulated equine chondrocytes in vitro
Martins, M. C., Peffers, M. J., Lee, K., & Rubio-Martinez, L. M. (2018). Effects of stanozolol on normal and IL-1β-stimulated equine chondrocytes in vitro. BMC VETERINARY RESEARCH, 14. doi:10.1186/s12917-018-1426-z
Biomarkers for equine joint injury and osteoarthritis
McIlwraith, C. W., Kawcak, C. E., Frisbie, D. D., Little, C. B., Clegg, P. D., Peffers, M. J., . . . Kraus, V. B. (2018). Biomarkers for equine joint injury and osteoarthritis. JOURNAL OF ORTHOPAEDIC RESEARCH, 36(3), 823-831. doi:10.1002/jor.23738
Osteoarthritis year in review 2017: genetics and epigenetics
Peffers, M. J., Balaskas, P., & Smagul, A. (2018). Osteoarthritis year in review 2017: genetics and epigenetics. OSTEOARTHRITIS AND CARTILAGE, 26(3), 304-311. doi:10.1016/j.joca.2017.09.009
The role of microRNA:target interactions in tendon dysfunction
Bardell, D. A., Peffers, M. J., Clegg, P. D., Molloy, A., & Whysall, K. A. (n.d.). The role of microRNA:target interactions in tendon dysfunction. Osteoarthritis and Cartilage.
Donor age affects proteome composition of tenocyte-derived engineered tendon
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2018). Donor age affects proteome composition of tenocyte-derived engineered tendon. BMC BIOTECHNOLOGY, 18. doi:10.1186/s12896-018-0414-5
Proteomic Analysis of Equine Plasma and Peritoneal Fluid in Strangulating Small Intestinal Disease
Bardell, D., Peffers, M. J., & Milner, P. (2018). Proteomic Analysis of Equine Plasma and Peritoneal Fluid in Strangulating Small Intestinal Disease. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
SYNOVIAL FLUID METABOLITE PROFILES DIFFER BETWEEN OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS
Anderson, J. R., Chokesuwattanaskul, S., Phelan, M. P., Welting, T. J. M., Lian, L. -Y., Peffers, M. J., & Wright, H. L. (2018). SYNOVIAL FLUID METABOLITE PROFILES DIFFER BETWEEN OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS. In RHEUMATOLOGY Vol. 57. Retrieved from https://www.webofscience.com/
2017
Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
Rubio-Martinez, L. M., Rioja, E., Martins, M. C., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. BMC VETERINARY RESEARCH, 13. doi:10.1186/s12917-017-1244-8
Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
Rubio Martinez, L. M., Rioja, E., Castro Martins, M., Wipawee, S., Clegg, P., & Peffers, M. J. (2017). Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro. Arthritis Research and Therapy. doi:10.1186/s12917-017-1244-8
Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females
Pease, L. I., Clegg, P. D., Proctor, C. J., Shanley, D. J., Cockell, S. J., & Peffers, M. J. (2017). Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. Scientific Reports, 7. doi:10.1038/s41598-017-14650-z
MicroRNA Profiling in Cartilage Ageing
Balaskas, P., Goljanek-Whysall, K., Clegg, P., Fang, Y., Cremers, A., Emans, P., . . . Peffers, M. (2017). MicroRNA Profiling in Cartilage Ageing. INTERNATIONAL JOURNAL OF GENOMICS, 2017. doi:10.1155/2017/2713725
Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.
Wardle, R., Pullman, J. A., Haldenby, S., Ressel, L., Pope, M., Clegg, P. D., . . . Peffers, M. J. (2017). Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.. Wellcome open research, 2, 60. doi:10.12688/wellcomeopenres.12176.2
Systems Approaches in Osteoarthritis: Identifying Routes to Novel Diagnostic and Therapeutic Strategies
Mueller, A. J., Peffers, M. J., Proctor, C. J., & Clegg, P. D. (2017). Systems Approaches in Osteoarthritis: Identifying Routes to Novel Diagnostic and Therapeutic Strategies. JOURNAL OF ORTHOPAEDIC RESEARCH, 35(8), 1573-1588. doi:10.1002/jor.23563
Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2017). Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis. Proteomics, 17(13-14). doi:10.1002/pmic.201700018
POOR CLINICAL RESPONSE TO AUTOLOGOUS CHONDROCYTE IMPLANTATION IS ASSOCIATED WITH A UNIQUE SYNOVIAL FLUID PROTEOME PROFILE
Hulme, C. H., Wilson, E. L., Peffers, M. J., Peffers, M. J., Fuller, H., Roberts, S., . . . Wright, K. T. (2017). POOR CLINICAL RESPONSE TO AUTOLOGOUS CHONDROCYTE IMPLANTATION IS ASSOCIATED WITH A UNIQUE SYNOVIAL FLUID PROTEOME PROFILE. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S92). doi:10.1016/j.joca.2017.02.146
Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles
Hulme, C. H., Wilson, E. L., Peffers, M. J., Roberts, S., Simpson, D. M., Richardson, J. B., . . . Wright, K. T. (2017). Autologous chondrocyte implantation-derived synovial fluids display distinct responder and non-responder proteomic profiles. Arthritis Research and Therapy, 19. doi:10.1186/s13075-017-1336-7
Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint
Davidson, R., Gardner, S., Jupp, O., Bullough, A., Butters, S., Watts, L., . . . Clark, I. (2017). Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint. Scientific Reports, 7. doi:10.1038/s41598-017-03629-5
THE EFFECT OF DONOR AGE ON ENGINEERED TENDON TISSUE DERIVED FROM TENOCYTES AND MESENCHYMAL STEM CELLS
Turlo, A. J., Kharaz, Y. A., Clegg, P. D., Anderson, J., & Peffers, M. J. (2017). THE EFFECT OF DONOR AGE ON ENGINEERED TENDON TISSUE DERIVED FROM TENOCYTES AND MESENCHYMAL STEM CELLS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S88). doi:10.1016/j.joca.2017.02.137
Neopeptide Analyser: A software tool for neopeptide discovery in proteomics data.
Peffers, M., Jones, A. R., McCabe, A., & Anderson, J. (2017). Neopeptide Analyser: A software tool for neopeptide discovery in proteomics data.. Wellcome open research, 2, 24. doi:10.12688/wellcomeopenres.11275.1
YEAR IN REVIEW - GENETICS/GENOMICS AND EPIGENETICS
Peffers, M. J. (2017). YEAR IN REVIEW - GENETICS/GENOMICS AND EPIGENETICS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S7). doi:10.1016/j.joca.2017.02.026
Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis
Steinbusch, M. M. F., Fang, Y., Milner, P. I., Clegg, P. D., Young, D. A., Welting, T. J. M., & Peffers, M. J. (2017). Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis. Scientific reports, 7, 11 pages. doi:10.1038/srep43558
2016
Comparison of protein extraction methods in tendon for mass spectrometry analysis
Ashraf Kharaz, Y., Zamboulis, D., Sander, K., Comerford, E., Clegg, P., & Peffers, M. (2016). Comparison of protein extraction methods in tendon for mass spectrometry analysis. In International Journal of Experimental Pathology Vol. 9 (pp. A26). Chester University.
Comparison of protein extraction methods in tendon for mass spectrometry analysis
Kharaz, Y. A., Zamboulis, D., Sanders, K., Comerford, E., Clegg, P., & Peffers, M. (2016). Comparison of protein extraction methods in tendon for mass spectrometry analysis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A26). Retrieved from https://www.webofscience.com/
A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells
Peffers, M. J., Collins, J., Loughlin, J., proctor, C., & Clegg, P. (2016). A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells. Stem Cell Research & Therapy. doi:10.1186/s13287-016-0384-2
Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq
Peffers, M. J., Goljanek-Whysall, K., Collins, J., Fang, Y., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq. PLOS ONE, 11(8). doi:10.1371/journal.pone.0160517
Proteomic differences between native and tissue-engineered tendon and ligament
Kharaz, Y. A., Tew, S. R., Peffers, M., Canty-Laird, E. G., & Comerford, E. (2016). Proteomic differences between native and tissue-engineered tendon and ligament. PROTEOMICS, 16(10), 1547-1556. doi:10.1002/pmic.201500459
BIG TASKS FOR SMALL RNAS; A NEW CLASS OF RNAS IN THE PATHGENESIS OF OSTEARTHRITIS
Peffers, M. J., Clegg, P. D., Boothroyd, E., Cremer, A., Durtel, D. A., Caron, M. M., & Welting, T. J. (2016). BIG TASKS FOR SMALL RNAS; A NEW CLASS OF RNAS IN THE PATHGENESIS OF OSTEARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S372). doi:10.1016/j.joca.2016.01.665
DO BIOACTIVE COMPOUNDS FROM CRUCIFEROUS VEGETABLES REACH THE KNEE JOINT?
Davidson, R. K., Gardner, S., Jupp, O., Bullough, A., Butters, S., Watts, L., . . . Clark, I. M. (2016). DO BIOACTIVE COMPOUNDS FROM CRUCIFEROUS VEGETABLES REACH THE KNEE JOINT?. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S459). doi:10.1016/j.joca.2016.01.838
IDENTIFICATION OF SERUM SNORNAS AS BIOMARKERS OF MUSCULOSKELETAL AGEING AND DISEASE
Peffers, M. J., Milner, P. M., Fang, Y., Young, D., Whysall, K., & Clegg, P. D. (2016). IDENTIFICATION OF SERUM SNORNAS AS BIOMARKERS OF MUSCULOSKELETAL AGEING AND DISEASE. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S41-S42). doi:10.1016/j.joca.2016.01.099
THE ROLE OF MICRORNAS IN OSTEOARTHRITIS AND AGEING RELATED FUNCTIONAL DECLINE IN JOINT TISSUE HOMEOSTASIS.
House, L., Bou-Gharios, G., Peffers, M., Milner, P., Clegg, P. D., Young, D. A., & Whysall, K. A. (2016). THE ROLE OF MICRORNAS IN OSTEOARTHRITIS AND AGEING RELATED FUNCTIONAL DECLINE IN JOINT TISSUE HOMEOSTASIS.. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S63-S64). doi:10.1016/j.joca.2016.01.141
AGE-RELATED CHANGES IN MESENCHYMAL STEM CELLS IDENTIFIED USING A MULTI-OMICS APPROACH
Peffers, M. J., Collins, J., Fang, Y., Goljanek-Whysall, K., Rushton, M., Loughlin, J., . . . Clegg, P. D. (2016). AGE-RELATED CHANGES IN MESENCHYMAL STEM CELLS IDENTIFIED USING A MULTI-OMICS APPROACH. EUROPEAN CELLS & MATERIALS, 31, 136-159. doi:10.22203/eCM.v031a10
Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition
Thorpe, C. T., Peffers, M. J., Simpson, D., Halliwell, E., Screen, H. R. C., & Clegg, P. D. (2016). Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. Scientific Reports, 6. doi:10.1038/srep20455
A role for small nucleolar RNAs in musculoskeletal ageing and osteoarthritis
Peffers, M., Steinbusch, M., Milner, P., Fang, Y., Young, D., Welting, T., & Clegg, P. (2016). A role for small nucleolar RNAs in musculoskeletal ageing and osteoarthritis. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A11). Retrieved from https://www.webofscience.com/
Characterization of Neopeptides in Equine Articular Cartilage Degradation
Peffers, M. J., Thornton, D. J., & Clegg, P. D. (2016). Characterization of Neopeptides in Equine Articular Cartilage Degradation. JOURNAL OF ORTHOPAEDIC RESEARCH, 34(1), 106-120. doi:10.1002/jor.22963
Influence of Ageing on Tendon Homeostasis
Birch, H. L., Peffers, M. J., & Clegg, P. D. (2016). Influence of Ageing on Tendon Homeostasis. METABOLIC INFLUENCES ON RISK FOR TENDON DISORDERS, 920, 247-260. doi:10.1007/978-3-319-33943-6_24
2015
Identification of Disease Specific Metabolic Fingerprints in Early Osteoarthritis
Peffers, M., Riggs, C., Phelan, M., & Clegg, P. (2015). Identification of Disease Specific Metabolic Fingerprints in Early Osteoarthritis. Equine Veterinary Journal, 47(S48), 13. doi:10.1111/evj.12486_28
Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization
Peffers, M., McDermott, B., Clegg, P., & Riggs, C. (2015). Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization. Osteoarthritis and Cartilage, 23(7), 1204-1213. doi:10.1016/j.joca.2015.03.019
Transcriptome analysis of ageing in uninjured human Achilles tendon
Peffers, M. J., Fang, Y., Cheung, K., Wei, T. K. J., Clegg, P. D., & Birch, H. L. (2015). Transcriptome analysis of ageing in uninjured human Achilles tendon. ARTHRITIS RESEARCH & THERAPY, 17. doi:10.1186/s13075-015-0544-2
2014
Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes
Tew, S., McDermott, B., Fentem, R. B., Peffers, M., & Clegg, P. (2014). Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes. Arthritis and Rheumatology, 66(11), 3052-3061. doi:10.1002/art.38849
Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation
Peffers, M., Thorpe, C., Collins, J., Eong, R., Wei, T., Screen, H., & Clegg, P. (2014). Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation. The Journal of Biological Chemistry, 289(37), 25867-25878. doi:10.1074/jbc.M114.566554
104 Characterisation Of The Proteome Of The Tendon Interfascicular Matrix
Thorpe, C., Peffers, M., Simpson, D., Halliwell, E., Screen, H., & Clegg, P. (2014). 104 Characterisation Of The Proteome Of The Tendon Interfascicular Matrix. In Abstracts (pp. A68.1-A68). BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine. doi:10.1136/bjsports-2014-094114.103
22 Transcriptomic Signatures Of Tendon Ageing
Peffers, M., Fang, Y., Birch, H., Pei, T. K. J., Cheung, K., & Clegg, P. (2014). 22 Transcriptomic Signatures Of Tendon Ageing. Abstracts, A14.2-A15. doi:10.1136/bjsports-2014-094114.22
79 Increased Matrix Production In Tendon Constructs Derived From Older Stem Cells
Peffers, M., & Clegg, P. (2014). 79 Increased Matrix Production In Tendon Constructs Derived From Older Stem Cells. In Abstracts (pp. A51.2-A52). BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine. doi:10.1136/bjsports-2014-094114.78
Comprehensive Protein Profiling of Synovial Fluid in Osteoarthritis
Peffers, M., Riggs, C., McDermott, B., & Clegg, P. (2014). Comprehensive Protein Profiling of Synovial Fluid in Osteoarthritis. Equine Veterinary Journal, 46(S47), 19. doi:10.1111/evj.12323_42
Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., Eijkel, G. B., Clegg, P. D., & Heeren, R. M. A. (2014). Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage. Arthritis Research and Therapy, 16. doi:10.1186/ar4560
Under pressure: the cell's response
Under pressure: the cell's response (2014). In International Journal of Experimental Pathology Vol. 95. Wiley. doi:10.1111/iep.12078
COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS
Peffers, M. J., McDermott, B. T., Riggs, C. M., & Clegg, P. D. (2014). COMPREHENSIVE PROTEIN PROFILING OF SYNOVIAL FLUID IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S65-S66). doi:10.1016/j.joca.2014.02.134
POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES
Peffers, M. J., Fentom, R., Tew, S. R., & Clegg, P. D. (2014). POST 'TRANSCRIPTIONAL GENE REGULATION IN AGEING CARTILAGE AND CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S62-S63). doi:10.1016/j.joca.2014.02.128
Biosynthetic alterations in collagen production in ruptured canine anterior cruciate ligament
Williamson, K. A., Peffers, M., Pettitt, R., Comerford, E., & Canty-Laird, E. G. (2014). Biosynthetic alterations in collagen production in ruptured canine anterior cruciate ligament. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A37). Retrieved from https://www.webofscience.com/
Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites
Peffers, M. J., McKnight, W., & Clegg, P. D. (2014). Characterisation of neopeptides in articular cartilage identifies novel degradative cleavage sites. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 95 (pp. A27-A28). Retrieved from https://www.webofscience.com/
Transcriptomic profiling of cartilage ageing.
Peffers, M. J., Liu, X., & Clegg, P. D. (2014). Transcriptomic profiling of cartilage ageing.. Genomics data, 2, 27-28. doi:10.1016/j.gdata.2014.03.001
2013
MALDI imaging mass spectrometry of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., & Eijkel, G. (2013). MALDI imaging mass spectrometry of ageing and osteoarthritic cartilage. In Farm animal proteomics 2013 (pp. 75-78). Brill | Wageningen Academic. doi:10.3920/9789086867769_024
Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Absolute Quantification of Selected Proteins in the Human Osteoarthritic Secretome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(10), 20658-20681. doi:10.3390/ijms141020658
Transcriptomic signatures in cartilage ageing
Peffers, M. J., Liu, X., & Clegg, P. D. (2013). Transcriptomic signatures in cartilage ageing. ARTHRITIS RESEARCH & THERAPY, 15(4). doi:10.1186/ar4278
AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. (2013). AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S63). doi:10.1016/j.joca.2013.02.140
TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING
Peffers, M. J., Tew, S. R., & Clegg, P. D. (2013). TRANSCRIPTOMIC SIGNATURES IN CARTILAGE AGEING. In OSTEOARTHRITIS AND CARTILAGE Vol. 21 (pp. S9). doi:10.1016/j.joca.2013.02.040
MALDI imaging mass spectrometry of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., & Eijkel, G. (2013). MALDI imaging mass spectrometry of ageing and osteoarthritic cartilage. In Farm animal proteomics 2013 (pp. 75-78). Wageningen Academic Publishers. doi:10.3920/978-90-8686-776-9_22
MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage
Peffers, M. J., Cillero-Pastor, B., Eijkel, G., Clegg, P. D., & Heeren, R. M. A. (2013). MALDI imaging mass spectrometry reveals peptide markers of ageing and osteoarthritic cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A12). Retrieved from https://www.webofscience.com/
Protein signatures of the human osteoarthritic cartilage secretome
Peffers, M. J., Beynon, R. J., & Clegg, P. D. (2013). Protein signatures of the human osteoarthritic cartilage secretome. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 94 (pp. A11-A12). Retrieved from https://www.webofscience.com/
Transcriptomic signatures in cartilage ageing
Peffers, M. J., Liu, X., & Clegg, P. D. (n.d.). Transcriptomic signatures in cartilage ageing. Arthritis Research & Therapy, 15(4). doi:10.1186/ar4278
2012
PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL
Peffers, M. J., Beynon, R. J., Thornton, D., & Clegg, P. D. (2012). PROTEOMIC CHARACTERISATION AND QUANTIFICATION OF AN IN-VITRO EARLY EQUINE OSTEOARTHRITIS MODEL. In OSTEOARTHRITIS AND CARTILAGE Vol. 20 (pp. S261-S262). doi:10.1016/j.joca.2012.02.439
ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2012). ABSOLUTE QUANTIFICATION OF CARTILAGE MATRIX PROTEINS. In RHEUMATOLOGY Vol. 51 (pp. 98). Retrieved from https://www.webofscience.com/
2011
Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions
Tew, S. R., Vasieva, O., Peffers, M. J., & Clegg, P. D. (2011). Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions. OSTEOARTHRITIS AND CARTILAGE, 19(8), 1036-1046. doi:10.1016/j.joca.2011.04.015
Absolute quantification of the equine early osteoarthritis secretome using QconCAT
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Absolute quantification of the equine early osteoarthritis secretome using QconCAT. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A20-A21). Retrieved from https://www.webofscience.com/
Protein profiling of pathological cartilage
Peffers, M. J., Beynon, R. J., Thornton, D. J., & Clegg, P. D. (2011). Protein profiling of pathological cartilage. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 92 (pp. A18-A19). Retrieved from https://www.webofscience.com/
2010
Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading
Peffers, M. J., Milner, P. I., Tew, S. R., & Clegg, P. D. (2010). Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading. OSTEOARTHRITIS AND CARTILAGE, 18(11), 1502-1508. doi:10.1016/j.joca.2010.08.011
CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED
Peffers, M. J., Clegg, P. D., Tew, S., & Milne, P. I. (2010). CYCLICAL HYPEROSMOLAR LOADING OF HUMAN ARTICULAR CHONDROCYTES INCREASES SOX9 GENE EXPRESSION AND P38 SIGNALLING IS REQUIRED. In OSTEOARTHRITIS AND CARTILAGE Vol. 18 (pp. S125). doi:10.1016/S1063-4584(10)60306-8
The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes
Peffers, M. J., Tew, S. R., Milner, P. I., & Clegg, P. D. (2010). The MEK-ERK signalling pathway plays a role in SOX9 gene expression in human articular chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 91 (pp. A38). Retrieved from https://www.webofscience.com/
2009
Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes
Tew, S. R., Peffers, M. J., McKay, T. R., Lowe, E. T., Khan, W. S., Hardingham, T. E., & Clegg, P. D. (2009). Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 297(4), C898-C906. doi:10.1152/ajpcell.00571.2008