Publications
2023
Where the metabolome meets the microbiome for pancreatic cancer detection.
Oldfield, L., & Costello, E. (2023). Where the metabolome meets the microbiome for pancreatic cancer detection.. Cell reports. Medicine, 4(9), 101011. doi:10.1016/j.xcrm.2023.101011
2022
United Kingdom Early Detection Initiative (UK-EDI): protocol for establishing a national multicentre cohort of individuals with new-onset diabetes for early detection of pancreatic cancer
Oldfield, L., Stott, M., Hanson, R., Jackson, R. J., Reynolds, W., Chandran-Gorner, V., . . . Costello, E. (2022). United Kingdom Early Detection Initiative (UK-EDI): protocol for establishing a national multicentre cohort of individuals with new-onset diabetes for early detection of pancreatic cancer. BMJ OPEN, 12(10). doi:10.1136/bmjopen-2022-068010
Recent advances in understanding pancreatic cancer.
Stott, M. C., Oldfield, L., Hale, J., Costello, E., & Halloran, C. M. (2022). Recent advances in understanding pancreatic cancer.. Faculty reviews, 11, 9. doi:10.12703/r/11-9
Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes
Oldfield, L., Evans, A., Rao, R. G., Jenkinson, C., Purewal, T., Psarelli, E. E., . . . Costello, E. (2022). Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes. EBIOMEDICINE, 75. doi:10.1016/j.ebiom.2021.103802
2021
The holding temperature of blood during a delay to processing can affect serum and plasma protein measurements
Ashworth, M., Small, B., Oldfield, L., Evans, A., Greenhalf, W., Halloran, C., & Costello, E. (2021). The holding temperature of blood during a delay to processing can affect serum and plasma protein measurements. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-85052-5
2020
Challenges and Opportunities for Early Pancreatic Cancer Detection: Role for Protein Biomarkers
Oldfield, L., Barrera, L., Williams, D., Evans, A. E., Neoptolemos, J., & Costello, E. (2020). Challenges and Opportunities for Early Pancreatic Cancer Detection: Role for Protein Biomarkers. In Molecular and Translational Medicine (pp. 73-82). Springer International Publishing. doi:10.1007/978-3-030-49476-6_4
Early detection of pancreatic cancer
Pereira, S. P., Oldfield, L., Ney, A., Hart, P. A., Keane, M. G., Pandol, S. J., . . . Costello, E. (2020). Early detection of pancreatic cancer. The Lancet Gastroenterology and Hepatology, 5(7), 698-710. doi:10.1016/S2468-1253(19)30416-9
2018
S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes
Nedjadi, T., Evans, A., Sheikh, A., Barerra, L., Al-Ghamdi, S., Oldfield, L., . . . Costello, E. (2018). S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes. BMC CANCER, 18. doi:10.1186/s12885-018-5161-4
Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker.
Martinez-Bosch, N., Barranco, L. E., Orozco, C. A., Moreno, M., Visa, L., Iglesias, M., . . . Navarro, P. (2018). Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker.. Oncotarget, 9(68), 32984-32996. doi:10.18632/oncotarget.26034
Development of Novel Diagnostic Pancreatic Tumor Biomarkers
Oldfield, L., Rao, R., Barrera, L. N., & Costello, E. (2018). Development of Novel Diagnostic Pancreatic Tumor Biomarkers. In Pancreatic Cancer (pp. 1241-1272). Springer New York. doi:10.1007/978-1-4939-7193-0_86
Pancreatic ductal adenocarcinoma is associated with high prevalence of pancretogenic diabetes mellitus in individuals with potentially resectable disease.
Rao, R. G., Oldfield, L., Evans, A., Greenhalf, W., Halloran, C., & Costello, E. (2018). Pancreatic ductal adenocarcinoma is associated with high prevalence of pancretogenic diabetes mellitus in individuals with potentially resectable disease.. In BRITISH JOURNAL OF SURGERY Vol. 105 (pp. 82). Retrieved from https://www.webofscience.com/
2017
Detecting Pancreatic Cancer Earlier: Identifying Type 3c Diabetes in Individuals Newly Diagnosed With Type 2 Diabetes
Oldfield, L., Rao, R., Purewal, T., Neoptolemos, J. P., Halloran, C. M., Greenhalf, W., & Costello, E. (2017). Detecting Pancreatic Cancer Earlier: Identifying Type 3c Diabetes in Individuals Newly Diagnosed With Type 2 Diabetes. In PANCREAS Vol. 46 (pp. 1425). Retrieved from https://www.webofscience.com/
The Prevalence of Diabetes Mellitus is Significantly Higher for Patients Undergoing Surgery for Pancreatic Ductal Adenocarcinoma Compared to Surgery for Other Pancreatic Pathologies
Rao, R. G., Costello, E., Halloran, C. M., Oldfield, L., Greenhalf, W., Ghaneh, P., . . . Mann, K. (2017). The Prevalence of Diabetes Mellitus is Significantly Higher for Patients Undergoing Surgery for Pancreatic Ductal Adenocarcinoma Compared to Surgery for Other Pancreatic Pathologies. In PANCREAS Vol. 46 (pp. 1403-1404). Retrieved from https://www.webofscience.com/
2016
Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus
Jenkinson, C., Elliott, V., Evans, A., Oldfield, L., Jenkins, R., O'Brien, D., . . . Costello-Goldring, E. (2016). Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clinical Cancer Research, 22(7), 1734-1743. doi:10.1158/1078-0432.ccr-15-0879
Exploring the Protein Profile of Pancreatic Cancer-Associated Diabetes
Oldfield, L., Jenkinson, C., Purewal, T., Sutton, R., Neoptolemos, J. P., Greenhalf, W., & Costello, E. (2016). Exploring the Protein Profile of Pancreatic Cancer-Associated Diabetes. PANCREAS, 45(10), 1531-1532. Retrieved from https://www.webofscience.com/
2015
Potential Biomarkers of Pancreatic Ductal Adenocarcinoma-Associated Diabetes
Oldfield, L., Jenkinson, C., Purewal, T., Sutton, R., Neoptolemos, J. P., Greenhalf, W., & Costello, E. (2015). Potential Biomarkers of Pancreatic Ductal Adenocarcinoma-Associated Diabetes. PANCREAS, 44(8), 1404-1405. Retrieved from https://www.webofscience.com/
2007
Comparative analysis of gamma-hydroxybutyrate and gamma-hydroxyvalerate using GC/MS and HPLC
Mercer, J. W., Oldfield, L. S., Hoffman, K. N., Shakleya, D. M., & Bell, S. C. (2007). Comparative analysis of gamma-hydroxybutyrate and gamma-hydroxyvalerate using GC/MS and HPLC. JOURNAL OF FORENSIC SCIENCES, 52(2), 383-388. doi:10.1111/j.1556-4029.2007.00392.x