Publications
2024
Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.
Norman, B. P., Sutherland, H., Wilson, P. J. M., Rutland, D. A., Milan, A. M., Hughes, A. T., . . . Ranganath, L. R. (2024). Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.. Journal of inherited metabolic disease, 47(4), 664-673. doi:10.1002/jimd.12728
Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget's disease of bone.
Phillips, J., Subedi, D., Lewis, S. C., Keerie, C., Cronin, O., Porteous, M., . . . Ralston, S. H. (2024). Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget's disease of bone.. Annals of the rheumatic diseases, 83(4), 529-536. doi:10.1136/ard-2023-224990
Alkaptonuria.
Bernardini, G., Braconi, D., Zatkova, A., Sireau, N., Kujawa, M. J., Introne, W. J., . . . Santucci, A. (2024). Alkaptonuria.. Nature reviews. Disease primers, 10(1), 16. doi:10.1038/s41572-024-00498-x
2022
Identifying joint-specific gait mechanisms causing impaired gait in alkaptonuria patients
Shepherd, H. R., Robinson, M. A., Ranganath, L. R., & Barton, G. J. (2022). Identifying joint-specific gait mechanisms causing impaired gait in alkaptonuria patients. GAIT & POSTURE, 91, 312-317. doi:10.1016/j.gaitpost.2021.10.034
2018
Reduction of frontal plane knee load caused by lateral trunk lean depends on step width
Anderson, J., King, S., Przybyla, A., Ranganath, L., & Barton, G. (2018). Reduction of frontal plane knee load caused by lateral trunk lean depends on step width. GAIT & POSTURE, 61, 483-487. doi:10.1016/j.gaitpost.2018.02.022
2015
Diagnostic tools and strategies for assessing disease progression in Alkaptonuria
Ranganath, L., Psarelli, E., Cox, T., & Gallagher, J. (2015). Diagnostic tools and strategies for assessing disease progression in Alkaptonuria. Expert Opinion in Orphan Drugs, 3(6), 705-717. doi:10.1517/21678707.2015
Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice
Keenan, C. M., Preston, A. J., Sutherland, H., Wilson, P. J., Psarelli, E. E., Cox, T. F., . . . Gallagher, J. A. (2015). Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice. JIMD REPORTS, VOL 24, 24, 45-50. doi:10.1007/8904_2015_437
Relationship Between Serum Concentrations of Nitisinone and Its Effect on Homogentisic Acid and Tyrosine in Patients with Alkaptonuria
Olsson, B., Cox, T. F., Psarelli, E. E., Szamosi, J., Hughes, A. T., Milan, A. M., . . . Ranganath, L. R. (2015). Relationship Between Serum Concentrations of Nitisinone and Its Effect on Homogentisic Acid and Tyrosine in Patients with Alkaptonuria. JIMD REPORTS, VOL 24, 24, 21-27. doi:10.1007/8904_2015_412
2014
Reversible Keratopathy Due to Hypertyrosinaemia Following Intermittent Low-Dose Nitisinone in Alkaptonuria: A Case Report
Stewart, R. M. K., Briggs, M. C., Jarvis, J. C., Gallagher, J. A., & Ranganath, L. (2014). Reversible Keratopathy Due to Hypertyrosinaemia Following Intermittent Low-Dose Nitisinone in Alkaptonuria: A Case Report. JIMD REPORTS, VOL 17, 17, 1-6. doi:10.1007/8904_2014_307
2011
A quantitative assessment of alkaptonuria: testing the reliability of two disease severity scoring systems.
Cox, T. F., & Ranganath, L. (2011). A quantitative assessment of alkaptonuria: testing the reliability of two disease severity scoring systems.. Journal of inherited metabolic disease, 34(6), 1153-1162. doi:10.1007/s10545-011-9367-8
Natural history of alkaptonuria revisited: analyses based on scoring systems.
Ranganath, L. R., & Cox, T. F. (2011). Natural history of alkaptonuria revisited: analyses based on scoring systems.. Journal of inherited metabolic disease, 34(6), 1141-1151. doi:10.1007/s10545-011-9374-9
The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.
Taylor, A., Boyde, A., Wilson, P., Jarvis, J., Davidson, J., Hunt, J., . . . Gallagher, J. (2011). The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.. Arthritis and rheumatism, 63(12), 3887-3896.
2009
Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in healthy normal weight subjects and obese patients with type 2 diabetes
Daousi, C., Wilding, J. P. H., Aditya, S., Durham, B. H., Cleator, J., Pinkney, J. H., & Ranganath, L. R. (2009). Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in healthy normal weight subjects and obese patients with type 2 diabetes. CLINICAL ENDOCRINOLOGY, 71(2), 195-201. doi:10.1111/j.1365-2265.2008.03451.x
2008
Alkaptonuria - a review of surgical and autopsy pathology
Helliwell, T. R., Gallagher, J. A., & Ranganath, L. (2008). Alkaptonuria - a review of surgical and autopsy pathology. HISTOPATHOLOGY, 53(5), 503-512. doi:10.1111/j.1365-2559.2008.03000.x