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Kristian Daly

Dr Kristian Daly
B.Sc., Ph.D

Contact

Nkd@liverpool.ac.uk

+44 (0)151 794 4259

Publications

Selected publications

  1. Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion (Journal article - 2013)
  2. Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease. (Journal article - 2012)
  3. Microarray analysis of butyrate regulated genes in colonic epithelial cells. (Journal article - 2006)
  4. The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis. (Journal article - 2005)
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2022

Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease

Kelly, J., Al-Rammahi, M., Daly, K., Flanagan, P. K., Urs, A., Cohen, M. C., . . . Shirazi-Beechey, S. P. (2022). Alterations of mucosa-attached microbiome and epithelial cell numbers in the cystic fibrosis small intestine with implications for intestinal disease. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-10328-3

DOI
10.1038/s41598-022-10328-3
Journal article

2021

Non-nutritive sweetener activation of the pig sweet taste receptor T1R2-T1R3 in vitro mirrors sweetener stimulation of the gut- expressed receptor in vivo

Daly, K., Al-Rammahi, M., Moran, A. W., Weatherburn, D., & Shirazi-Beechey, S. (2021). Non-nutritive sweetener activation of the pig sweet taste receptor T1R2-T1R3 in vitro mirrors sweetener stimulation of the gut- expressed receptor in vivo. Biochemical and Biophysical Research Communications. doi:10.1016/j.bbrc.2021.01.032

DOI
10.1016/j.bbrc.2021.01.032
Journal article

Nutrient sensing of gut luminal environment

Moran, A., Daly, K., Al-Rammahi, M., & Shirazi-Beechey, S. (n.d.). Nutrient sensing of gut luminal environment. Proceedings of the Nutrition Society. doi:10.1017/S0029665120007120

DOI
10.1017/S0029665120007120
Journal article

2020

Toll-like receptor 9 expressed in proximal intestinal enteroendocrine cells detects bacteria resulting in secretion of cholecystokinin

Daly, K., Burdyga, G., Al-Rammahi, M., Moran, A. W., Eastwood, C., & Shirazi-Beechey, S. P. (2020). Toll-like receptor 9 expressed in proximal intestinal enteroendocrine cells detects bacteria resulting in secretion of cholecystokinin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 525(4), 936-940. doi:10.1016/j.bbrc.2020.02.163

DOI
10.1016/j.bbrc.2020.02.163
Journal article

Consumption of a Natural High-Intensity Sweetener Enhances Activity and Expression of Rabbit Intestinal Na+/Glucose Cotransporter 1 (SGLT1) and Improves Colibacillosis-Induced Enteric Disorders

Shirazi-Beechey, S. (2020). Consumption of a Natural High-Intensity Sweetener Enhances Activity and Expression of Rabbit Intestinal Na+/Glucose Cotransporter 1 (SGLT1) and Improves Colibacillosis-Induced Enteric Disorders. Journal of Agricultural and Food Chemistry. doi:10.1021/acs.jafc.9b04995

DOI
10.1021/acs.jafc.9b04995
Journal article

2019

The effect of milk replacer composition on the intestinal microbiota of pre-ruminant dairy calves

Badman, J., Daly, K., Kelly, J., Moran, A., Cameron, J., Watson, I., . . . Shirazi-Beechey, S. P. (2019). The effect of milk replacer composition on the intestinal microbiota of pre-ruminant dairy calves. Frontiers in Veterinary Science. doi:10.3389/fvets.2019.00371

DOI
10.3389/fvets.2019.00371
Journal article

Host selectively contributes to shaping intestinal microbiota of carnivorous and omnivorous fish

Daly, K., Kelly, J., Moran, A., Bristow, R., Young, I., Cossins, A., . . . Shirazi-Beechey, S. (2019). Host selectively contributes to shaping intestinal microbiota of carnivorous and omnivorous fish. The Journal of General and Applied Microbiology, 65(3), 129-136. doi:10.2323/jgam.2018.07.003

DOI
10.2323/jgam.2018.07.003
Journal article

2018

Sweet Sensing by Gut Bacteria

Daly, K. P. (2018, July 11). Sweet Sensing by Gut Bacteria [Invited Oral Presentation]. American Society of Animal Sciences Annual Meeting, Vancouver, Canada.

Performance

2017

Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals

Wolnerhanssen, B. K., Moran, A. W., Burdyga, G., Meyer-Gerspach, A. C., Peterli, R., Manz, M., . . . Shirazi-Beechey, S. P. (2017). Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals. Scientific Reports, 7. doi:10.1038/s41598-017-08487-9

DOI
10.1038/s41598-017-08487-9
Journal article

Role of intestinal nutrient sensors in secretion of satiety hormones regulating appetite

Daly, K. P., & Shirazi-Beechey, S. P. (2017, July 10). Role of intestinal nutrient sensors in secretion of satiety hormones regulating appetite [Presentation]. Baltimore, Maryland, USA.

Performance

2016

2015

Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus

Daly, K., Darby, A., Hall, N., Wilkinson, M., Pongchaikul, P., Bravo, D., & Shirazi-Beechey, S. (2015). Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus. Environmental Microbiology, 18(7), 2159-2171. doi:10.1111/1462-2920.12942

DOI
10.1111/1462-2920.12942
Journal article

2014

Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing.

Shirazi-Beechey, S., Daly, K., Al-Rammahi, M., Moran, A., & Bravo, D. (2014). Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing.. The British journal of nutrition, 111(S1), S8-S15. doi:10.1017/S0007114513002286

DOI
10.1017/S0007114513002286
Journal article

Characterization of the pig sweet taste receptor by heterologous expression

Daly, K., Shirazi-Beechey, S., & Daly, K. (2014). Characterization of the pig sweet taste receptor by heterologous expression [Public Performance].

Performance

Dietary supplementation with lactose or artificial sweetener enhances swine gut Lactobacillus population abundance.

Daly, K., Darby, A., Hall, N., Nau, A., Bravo, D., & Shirazi-Beechey, S. (2014). Dietary supplementation with lactose or artificial sweetener enhances swine gut Lactobacillus population abundance.. The British Journal of Nutrition, 111(S1), S30-S35. doi:10.1017/S0007114513002274

DOI
10.1017/S0007114513002274
Journal article

2013

Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion

Daly, K., Al-Rammahi, M., Moran, A., Marcello, M., Ninomiya, Y., & Shirazi-Beechey, S. P. (2013). Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 304(3), G271-G282. doi:10.1152/ajpgi.00074.2012

DOI
10.1152/ajpgi.00074.2012
Journal article

2012

Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transport

Daly, K., Al-Rammahi, M., Arora, D. K., Moran, A. W., Proudman, C. J., Ninomiya, Y., & Shirazi-Beechey, S. P. (2012). Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transport. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 303(2), R199-R208. doi:10.1152/ajpregu.00031.2012

DOI
10.1152/ajpregu.00031.2012
Journal article

Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease.

Daly, K., Proudman, C. J., Duncan, S. H., Flint, H. J., Dyer, J., & Shirazi-Beechey, S. P. (2012). Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease.. The British journal of nutrition, 107(7), 989-995. doi:10.1017/s0007114511003825

DOI
10.1017/s0007114511003825
Journal article

Sweet sensing by swine gut lactobacilli enhances their growth and population abundance

Daly, K. (2012). Sweet sensing by swine gut lactobacilli enhances their growth and population abundance [Public Performance].

Performance

Sweet sensing by swine gut lactobacillus enhances its growth and population abundance

Daly, K. (2012). Sweet sensing by swine gut lactobacillus enhances its growth and population abundance [Public Performance].

Performance

Sweet sensing by swine gut lactobacillus enhances its growth and population abundance

Daly, K. (2012). Sweet sensing by swine gut lactobacillus enhances its growth and population abundance [Public Performance].

Performance

2011

Glucose sensing and signalling; regulation of intestinal glucose transport

Shirazi-Beechey, S. P., Moran, A. W., Batchelor, D. J., Daly, K., & Al-Rammahi, M. (2011). Glucose sensing and signalling; regulation of intestinal glucose transport. PROCEEDINGS OF THE NUTRITION SOCIETY, 70(2), 185-193. doi:10.1017/S0029665111000103

DOI
10.1017/S0029665111000103
Journal article

Effect of dietary change on equine and swine gut microbiota

Daly, K. (2011). Effect of dietary change on equine and swine gut microbiota [Public Performance].

Performance

2010

Expression of Na<SUP>+</SUP>/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners

Moran, A. W., Al-Rammahi, M. A., Arora, D. K., Batchelor, D. J., Coulter, E. A., Daly, K., . . . Shirazi-Beechey, S. P. (2010). Expression of Na<SUP>+</SUP>/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners. BRITISH JOURNAL OF NUTRITION, 104(5), 637-646. doi:10.1017/S0007114510000917

DOI
10.1017/S0007114510000917
Journal article

Effect of diet on equine gut microbiota

Daly, K. (2010). Effect of diet on equine gut microbiota [Public Performance].

Performance

Nutrient sensing mechanisms underlying CCK release

Daly, K. (2010). Nutrient sensing mechanisms underlying CCK release [Public Performance].

Performance

2008

Identification of the butyrate/cytokine response element of the monocarboxylate transporter 1 gene

Daly, K. (2008). Identification of the butyrate/cytokine response element of the monocarboxylate transporter 1 gene [Public Performance].

Performance

2007

Intestinal glucose sensing and regulation of intestinal glucose absorption.

Dyer, J., Daly, K., Salmon, K. S. H., Arora, D. K., Kokrashvili, Z., Margolskee, R. F., & Shirazi-Beechey, S. P. (2007). Intestinal glucose sensing and regulation of intestinal glucose absorption.. Biochemical Society transactions, 35(Pt 5), 1191-1194. doi:10.1042/bst0351191

DOI
10.1042/bst0351191
Journal article

Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation

Thibault, R., de Coppet, P., Daly, K., Bourreille, A., Cuff, M. A., Bonnet, C., . . . Segain, J. P. (2007). Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation. Gastroenterolgy, 133, 1916-1927.

Journal article

T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.

Margolskee, R. F., Dyer, J., Kokrashvili, Z., Salmon, K. S. H., Ilgemes, E., Daly, K., . . . Shirazi-Beechey, S. P. (2007). T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.. Proceedings of the National Acadamy of Sciences USA, 104, 15075-15080.

Journal article

2006

Microarray analysis of butyrate regulated genes in colonic epithelial cells.

Daly, K., & Shirazi-Beechey, S. P. (2006). Microarray analysis of butyrate regulated genes in colonic epithelial cells.. DNA and cell biology, 25(1), 49-62. doi:10.1089/dna.2006.25.49

DOI
10.1089/dna.2006.25.49
Journal article

2005

The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis.

Daly, K., Cuff, M. A., Fung, F., & Shirazi-Beechey, S. P. (2005). The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis.. Biochemical Society transactions, 33(Pt 4), 733-735. doi:10.1042/bst0330733

DOI
10.1042/bst0330733
Journal article

2003

Design and evaluation of group-specific oligonucleotide probes for quantitative analysis of intestinal ecosystems: their application to assessment of equine colonic microflora.

Daly, K., & Shirazi-Beechey, S. P. (2003). Design and evaluation of group-specific oligonucleotide probes for quantitative analysis of intestinal ecosystems: their application to assessment of equine colonic microflora.. FEMS microbiology ecology, 44(2), 243-252. doi:10.1016/s0168-6496(03)00032-1

DOI
10.1016/s0168-6496(03)00032-1
Journal article

2001

Bacterial diversity within the equine large intestine as revealed by molecular analysis of cloned 16S rRNA genes

Daly, K. P., Stewart, C. S., Flint, H. J., & Shirazi-Beechey, S. P. (2001). Bacterial diversity within the equine large intestine as revealed by molecular analysis of cloned 16S rRNA genes. FEMS Microbiology Ecology, 38, 141-151. doi:10.1111/j.1574-6941.2001.tb00892

DOI
10.1111/j.1574-6941.2001.tb00892
Journal article

Isolation and characterization of a novel hydrocarbon-degrading, Gram-positive bacterium, isolated from intertidal beach sediment, and description of Planococcus alkanoclasticus sp. nov.

Engelhardt, M. A., Daly, K. P., Swannell, R. P., & Head, I. M. (2001). Isolation and characterization of a novel hydrocarbon-degrading, Gram-positive bacterium, isolated from intertidal beach sediment, and description of Planococcus alkanoclasticus sp. nov.. Journal of Applied Microbiology, 90(2), 237-247. doi:10.1046/j.1365-2672.2001.01241

DOI
10.1046/j.1365-2672.2001.01241
Journal article

2000

Development of oligonucleotide probes and PCR primers for detecting phylogenetic subgroups of sulfate-reducing bacteria.

Daly, K., Sharp, R. J., & McCarthy, A. J. (2000). Development of oligonucleotide probes and PCR primers for detecting phylogenetic subgroups of sulfate-reducing bacteria.. Microbiology (Reading, England), 146 ( Pt 7), 1693-1705. doi:10.1099/00221287-146-7-1693

DOI
10.1099/00221287-146-7-1693
Journal article

1997

Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.

Daly, K. P., Dixon, A. C., Swannell, R. P., Lepo, J. E., & Head, I. M. (1997). Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.. Journal of Applied Microbiology, 83(4), 421-429. doi:10.1046/j.1365-2672.1997.00254

DOI
10.1046/j.1365-2672.1997.00254
Journal article

Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.

Daly, K. P., Dixon, A. C., Swannell, R. P., Lepo, J. E., & Head, I. M. (1997). Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.. Journal of Applied Microbiology, 83(4), 421-429. doi:10.1046/j.1365-2672.1997.00254

DOI
10.1046/j.1365-2672.1997.00254
Journal article