Publications
2025
Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition.
Daly, J. L., Chen, K. -E., Butkovič, R., Guo, Q., Healy, M. D., Pennink, E., . . . Cullen, P. J. (2025). Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through autoinhibition. . Proceedings of the National Academy of Sciences of the United States of America, 122(27), e2501111122. doi:10.1073/pnas.2501111122
Ritscher-Schinzel syndrome can be characterized as an endosomal recyclinopathy.
Kato, K., Nishio, Y., McMillan, K. J., Al-Maraghi, A., Kroes, H. Y., Abdel-Hamid, M. S., . . . Cullen, P. J. (2025). Ritscher-Schinzel syndrome can be characterized as an endosomal recyclinopathy.. Science translational medicine, 17(805), eadt2426. doi:10.1126/scitranslmed.adt2426
Identification of a VPS29 isoform with restricted association to Retriever and Retromer accessory proteins through auto-inhibition
2022
Using Lentiviral shRNA Delivery to Knock Down Proteins in Cultured Neurons and In Vivo
Wilkinson, K. A., McMillan, K. J., Banks, P. J., Carmichael, R. E., Nakamura, Y., Bashir, Z. I., . . . Henley, J. M. (2022). Using Lentiviral shRNA Delivery to Knock Down Proteins in Cultured Neurons and In Vivo. In Neuromethods (pp. 1-17). Springer US. doi:10.1007/978-1-0716-2569-9_1
2021
Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2.
McMillan, K. J., Banks, P. J., Hellel, F. L., Carmichael, R. E., Clairfeuille, T., Evans, A. J., . . . Cullen, P. J. (2021). Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2.. eLife, 10, e59432. doi:10.7554/elife.59432
2019
Retromer Controls Planar Polarity Protein Levels and Asymmetric Localization at Intercellular Junctions.
Strutt, H., Langton, P. F., Pearson, N., McMillan, K. J., Strutt, D., & Cullen, P. J. (2019). Retromer Controls Planar Polarity Protein Levels and Asymmetric Localization at Intercellular Junctions.. Current biology : CB, 29(3), 484-491.e6. doi:10.1016/j.cub.2018.12.027
2017
Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo.
McMillan, K. J., Murray, T. K., Bengoa-Vergniory, N., Cordero-Llana, O., Cooper, J., Buckley, A., . . . Caldwell, M. A. (2017). Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo.. Molecular therapy : the journal of the American Society of Gene Therapy, 25(10), 2404-2414. doi:10.1016/j.ymthe.2017.08.017
The emerging role of retromer in neuroprotection.
McMillan, K. J., Korswagen, H. C., & Cullen, P. J. (2017). The emerging role of retromer in neuroprotection.. Current opinion in cell biology, 47, 72-82. doi:10.1016/j.ceb.2017.02.004
2016
Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins.
McMillan, K. J., Gallon, M., Jellett, A. P., Clairfeuille, T., Tilley, F. C., McGough, I., . . . Cullen, P. J. (2016). Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins.. The Journal of cell biology, 214(4), 389-399. doi:10.1083/jcb.201604057
2014
Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.
McGough, I. J., Steinberg, F., Jia, D., Barbuti, P. A., McMillan, K. J., Heesom, K. J., . . . Cullen, P. J. (2014). Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.. Current biology : CB, 24(14), 1670-1676. doi:10.1016/j.cub.2014.06.024