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Mark Senior

Professor Mark Senior
BVSc PhD SFHEA CertVA DipECVAA MRCVS

Contact

J.M.Senior@liverpool.ac.uk

http://www.liv.ac.uk/vets/departments/clinical/anaesthesia/mark.htm

+44 (0)151 794 6052

+44 (0)151 795 6052

+44 (0)151 795 6241

Publications

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2024

Allogenic platelet-rich plasma and platelet-rich plasma extracellular vesicles alter the proteome of tenocytes in an in vitro equine model of tendon inflammation: A pilot study

DOI
10.1101/2024.08.27.609926
Preprint

2022

2021

2020

2019

Update in advances in pain management for the equine practitioner

Taylor, P. M., & Senior, M. (2019). Update in advances in pain management for the equine practitioner. EQUINE VETERINARY EDUCATION, 31(7), 340-342. doi:10.1111/eve.13009

DOI
10.1111/eve.13009
Journal article

2018

2017

2016

Evaluation of a new handheld point-of-care blood gas analyser using 100 equine blood samples

Bardell, D., West, E., & Senior, J. M. (2017). Evaluation of a new handheld point-of-care blood gas analyser using 100 equine blood samples. VETERINARY ANAESTHESIA AND ANALGESIA, 44(1), 77-85. doi:10.1111/vaa.12392

DOI
10.1111/vaa.12392
Journal article

Suspected vagal reflex bradycardia in a calf undergoing surgical resection of an infected urachus

Scarabelli, S., Holman, A. N., & Senior, M. (2016). Suspected vagal reflex bradycardia in a calf undergoing surgical resection of an infected urachus. Veterinary Record Case Reports, 4(1). doi:10.1136/vetreccr-2015-000288

DOI
10.1136/vetreccr-2015-000288
Journal article

Anaesthesia and drug interactions in dogs and cats

Zoff, A., Thompson, K., & Senior, M. (2016). Anaesthesia and drug interactions in dogs and cats. IN PRACTICE, 38(4), 167-175. doi:10.1136/inp.i1477

DOI
10.1136/inp.i1477
Journal article

2015

Mitigating the risk of airway obstruction during recovery from anaesthesia: The way is far from clear

Senior, J. M. (2015). Mitigating the risk of airway obstruction during recovery from anaesthesia: The way is far from clear. EQUINE VETERINARY EDUCATION, 27(5), 244-246. doi:10.1111/eve.12312

DOI
10.1111/eve.12312
Journal article

Barking up the wrong tree: Would international guidelines improve safety in equine anaesthesia?

Senior, J. M. (2015). Barking up the wrong tree: Would international guidelines improve safety in equine anaesthesia?. EQUINE VETERINARY JOURNAL, 47(1), 14-15. doi:10.1111/evj.12348

DOI
10.1111/evj.12348
Journal article

2014

Factors associated with survival to hospital discharge following endoscopic treatment for synovial sepsis in 214 horses

Milner, P., Bardell, D., Warner, L., Packer, M., Senior, M., Singer, E., & Archer, D. (2014). Factors associated with survival to hospital discharge following endoscopic treatment for synovial sepsis in 214 horses. Equine Veterinary Journal, 46(6), 701-705. doi:10.1111/evj.12212

DOI
10.1111/evj.12212
Journal article

Comparison of the EPOC and i-STAT analysers for canine blood gas and electrolyte analysis

West, E., Bardell, D., & Senior, M. (2014). Comparison of the EPOC and i-STAT analysers for canine blood gas and electrolyte analysis. Journal of Small Animal Practice, 55(03), 139-144. doi:10.1111/jsap.12177

DOI
10.1111/jsap.12177
Journal article

2013

Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis

Zamboulis, D. E., Senior, J. M., Clegg, P. D., & Milner, P. I. (2013). Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis. The Veterinary Journal. doi:10.1016/j.tvjl.2013.08.017

DOI
10.1016/j.tvjl.2013.08.017
Journal article

Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis.

Zamboulis, D. E., Senior, M., Clegg, P. D., & Milner, P. I. (2013). Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis.. Veterinary journal (London, England : 1997), 198(2), 472-478. doi:10.1016/j.tvjl.2013.08.017

DOI
10.1016/j.tvjl.2013.08.017
Journal article

Not small horses: improving treatments for donkeys

Senior, J. M. (2013). Not small horses: improving treatments for donkeys. VETERINARY RECORD, 173(12), 292-293. doi:10.1136/vr.f5646

DOI
10.1136/vr.f5646
Journal article

Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia

Zamboulis, D. E., Senior, J. M., Clegg, P. D., Gallagher, J. A., Carter, S. D., & Milner, P. I. (2013). Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia. PURINERGIC SIGNALLING, 9(3), 383-393. doi:10.1007/s11302-013-9356-5

DOI
10.1007/s11302-013-9356-5
Journal article

Morbidity, mortality, and risk of general anesthesia in horses.

Senior, J. M. (2013). Morbidity, mortality, and risk of general anesthesia in horses.. The Veterinary clinics of North America. Equine practice, 29(1), 1-18. doi:10.1016/j.cveq.2012.11.007

DOI
10.1016/j.cveq.2012.11.007
Journal article

Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis

Zamboulis, D. E., Senior, M., Clegg, P. D., & Milner, P. I. (2013). Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis. VETERINARY JOURNAL, 198(2), 472-478. doi:10.1016/j.tvjl.2013.08.017

DOI
10.1016/j.tvjl.2013.08.017
Journal article

Retrospective study of the risk factors and prevalence of regurgitation in dogs undergoing anaesthesia

de Miguel-Garcia, C., Dugdale, A., Pinchbeck, G. L., & Senior, J. M. (2013). Retrospective study of the risk factors and prevalence of regurgitation in dogs undergoing anaesthesia. The Open Veterinary Science Journal, 7, 6-11.

Journal article

2011

The prevalence and nature of cardiac arrhythmias in horses following general anaesthesia and surgery

Morgan, R. A., Raftery, A. G., Cripps, P., Senior, J. M., & McGowan, C. M. (2011). The prevalence and nature of cardiac arrhythmias in horses following general anaesthesia and surgery. ACTA VETERINARIA SCANDINAVICA, 53. doi:10.1186/1751-0147-53-62

DOI
10.1186/1751-0147-53-62
Journal article

Plasma endotoxin in horses presented to an equine referral hospital: Correlation to selected clinical parameters and outcomes

Senior, J. M., Proudman, C. J., Leuwer, M., & Carter, S. D. (2011). Plasma endotoxin in horses presented to an equine referral hospital: Correlation to selected clinical parameters and outcomes. EQUINE VETERINARY JOURNAL, 43(5), 585-591. doi:10.1111/j.2042-3306.2010.00328.x

DOI
10.1111/j.2042-3306.2010.00328.x
Journal article

Preliminary evaluation of a new handheld point-of-care blood gas analyser using 50 canine blood samples

West, E., Bardell, D., & Senior, J. M. (2011). Preliminary evaluation of a new handheld point-of-care blood gas analyser using 50 canine blood samples. Proceedings of the Autumn 2011 Association of Veterinary Anaesthetists Congress,, 1, 28.

Journal article

Use of acetaminophen (paracetamol) as a short-term adjunctive analgesic in a laminitic pony

West, E., Bardell, D., Morgan, R., & Senior, M. (2011). Use of acetaminophen (paracetamol) as a short-term adjunctive analgesic in a laminitic pony. VETERINARY ANAESTHESIA AND ANALGESIA, 38(5), 521-522. doi:10.1111/j.1467-2995.2011.00639.x

DOI
10.1111/j.1467-2995.2011.00639.x
Journal article

2010

Pain after injection of a new formulation of propofol in six dogs

Minghella, E., Benmansour, P., Iff, I., Senior, J. M., & Mosing, M. (2010). Pain after injection of a new formulation of propofol in six dogs. VETERINARY RECORD, 167(22), 866-867. doi:10.1136/vr.c5736

DOI
10.1136/vr.c5736
Journal article

A study of the correlation between objective and subjective indices of recovery quality after inhalation anaesthesia in equids

Portier, K. G., Sena, A., Senior, M., & Clutton, R. E. (2010). A study of the correlation between objective and subjective indices of recovery quality after inhalation anaesthesia in equids. VETERINARY ANAESTHESIA AND ANALGESIA, 37(4), 329-336. doi:10.1111/j.1467-2995.2010.00542.x

DOI
10.1111/j.1467-2995.2010.00542.x
Journal article

Identification of P2X1-3 receptors in equine nervous tissue

Zamboulis, D. E., Senior, J. M., Clegg, P. D., Carter, S. D., Gallagher, J., & Milner, P. I. (2010). Identification of P2X1-3 receptors in equine nervous tissue. Proceedings of the UK Purine Club Symposium, Nottingham, 1, 42.

Journal article

Identification of P2X1-3 receptors in equine nervous tissue

Zamboulis, D. E., Senior, J. M., Clegg, P. D., Carter, S. D., Gallagher, J., & Milner, P. I. (2010). Identification of P2X1-3 receptors in equine nervous tissue. In Proceedings of the UK Purine Club Symposium (pp. 42). Nottingham: UK Purine Club.

Conference Paper

equine anaesthesia/ pain

Senior, J. M. (2010). equine anaesthesia/ pain. In A. H. A. Dugdale (Ed.), Veterinary Anaesthesia Principles to practice. Oxford: Wiley-Blackwell.

Chapter

2008

Clinical evaluation of alfaxalone in cyclodextrin for the induction of anaesthesia in rabbits

Grint, N. J., Smith, H. E., & Senior, J. M. (2008). Clinical evaluation of alfaxalone in cyclodextrin for the induction of anaesthesia in rabbits. VETERINARY RECORD, 163(13), 395-396. doi:10.1136/vr.163.13.395

DOI
10.1136/vr.163.13.395
Journal article

The Effects of Anesthesia on Laryngeal Function and Laryngeal/Pharyngeal Trauma in the Horse

Bradbury, L. A., Dugdale, A. H. A., Knottenbelt, D. C., Mackane, S. A., & Senior, J. M. (2008). The Effects of Anesthesia on Laryngeal Function and Laryngeal/Pharyngeal Trauma in the Horse. Journal of Equine Veterinary Science, 28(8), 461-467. doi:10.1016/j.jevs.2008.07.006

DOI
10.1016/j.jevs.2008.07.006
Journal article

2007

Reported morbidities following 861 anaesthetics given at four equine hospitals

Senior, J. M., Pinchbeck, G. L., Allister, R., Dugdale, A. H. A., Clark, L., Clutton, R. E., . . . Clegg, P. D. (2007). Reported morbidities following 861 anaesthetics given at four equine hospitals. VETERINARY RECORD, 160(12), 407-408. doi:10.1136/vr.160.12.407

DOI
10.1136/vr.160.12.407
Journal article

The effect of inotropic and/or vasopressor support on postoperative survival following equine colic surgery

Dugdale, A. H. A., Langford, J., Mark Senior, J., & Proudman, C. J. (2007). The effect of inotropic and/or vasopressor support on postoperative survival following equine colic surgery. VETERINARY ANAESTHESIA AND ANALGESIA, 34(2), 82-88. doi:10.1111/j.1467-2995.2006.00299.x

DOI
10.1111/j.1467-2995.2006.00299.x
Journal article

'Comparison of two doses of alphaxalone in cyclodextrin in rabbits'

Smith, H., Grint, N., & Senior, J. M. (2007). 'Comparison of two doses of alphaxalone in cyclodextrin in rabbits'. ECVA/AVA Autumn conference Leipzig, Germany proceedings, 1, 24.

Journal article

'Laryngeal function during anaesthesia'

Bradbury, L., Bardell, D., Dugdale, A. H. A., Knottenbelt, D. C., McKane, S., & Senior, J. M. (2007). 'Laryngeal function during anaesthesia'. ECVA/ AVA Spring conference proceedings Paris, 1, 46.

Journal article

Prevalence of and risk factors for post-operative colic in horses after non-abdominal surgery

Pinchbeck, G., Allister, R., Dugdale, A., Clegg, P., & Senior, M. (2007). Prevalence of and risk factors for post-operative colic in horses after non-abdominal surgery. In PREVENTIVE VETERINARY MEDICINE Vol. 81 (pp. 220). Retrieved from https://www.webofscience.com/

Conference Paper

Use of rocuronium administered by continuous infusion in dogs

Alderson, B., Senior, J. M., Jones, R. S., & Dugdale, A. H. A. (2007). Use of rocuronium administered by continuous infusion in dogs. VETERINARY ANAESTHESIA AND ANALGESIA, 34(4), 251-256. doi:10.1111/j.1467-2995.2006.00307.x

DOI
10.1111/j.1467-2995.2006.00307.x
Journal article

Use of sodium nitroprusside in the anaesthetic protocol of a patent ductus arteriosus ligation in a dog

Humm, K. R., Senior, J. M., Dugdale, A. H. A., & Surnmerfield, N. J. (2007). Use of sodium nitroprusside in the anaesthetic protocol of a patent ductus arteriosus ligation in a dog. VETERINARY JOURNAL, 173(1), 194-196. doi:10.1016/j.tvjl.2005.09.005

DOI
10.1016/j.tvjl.2005.09.005
Journal article

2006

Tracheal necrosis following tracheal intubation in a dog

Alderson, B., Senior, J. M., & Dugdale, A. H. A. (2006). Tracheal necrosis following tracheal intubation in a dog. JOURNAL OF SMALL ANIMAL PRACTICE, 47(12), 754-756. doi:10.1111/j.1748-5827.2006.00161.x

DOI
10.1111/j.1748-5827.2006.00161.x
Journal article

Prospective evaluation of postoperative pain in cats undergoing ovariohysterectomy by a midline or flank approach

Burrow, R., Wawra, E., Pinchbeck, G., Senior, M., & Dugdale, A. (2006). Prospective evaluation of postoperative pain in cats undergoing ovariohysterectomy by a midline or flank approach. VETERINARY RECORD, 158(19), 657-661. doi:10.1136/vr.158.19.657

DOI
10.1136/vr.158.19.657
Journal article

'My horse needs sedating'

Senior, J. M. (2006). 'My horse needs sedating'. Horse and Rider, 23-25.

Journal article

A comparison of cross-country recovery rates at CCI 2* with and without steeplechase competitions.

Murray, J. K., Senior, J. M., & Singer, E. R. (2006). A comparison of cross-country recovery rates at CCI 2* with and without steeplechase competitions.. Equine veterinary journal. Supplement, (36), 133-138. doi:10.1111/j.2042-3306.2006.tb05529.x

DOI
10.1111/j.2042-3306.2006.tb05529.x
Journal article

Post anaesthetic colic in horses: a preventable complication?

Senior, J. M., Pinchbeck, G. L., Allister, R., Dugdale, A. H. A., Clark, L., Clutton, R. E., . . . Clegg, P. D. (2006). Post anaesthetic colic in horses: a preventable complication?. EQUINE VETERINARY JOURNAL, 38(5), 479-484. doi:10.2746/042516406778400673

DOI
10.2746/042516406778400673
Journal article

Pre-operative and anaesthesia-related risk factors for mortality in equine colic cases

Proudman, C. J., Dugdale, A. H. A., Senior, J. M., Edwards, G. B., Smith, J. E., Leuwer, M. L., & French, N. P. (2006). Pre-operative and anaesthesia-related risk factors for mortality in equine colic cases. PFERDEHEILKUNDE, 22(4), 487. Retrieved from https://www.webofscience.com/

Journal article

Pre-operative and anaesthesia-related risk factors for mortality in equine colic cases

Proudman, C. J., Dugdale, A. H. A., Senior, J. M., Edwards, G. B., Smith, J. E., Leuwer, M. L., & French, N. P. (2006). Pre-operative and anaesthesia-related risk factors for mortality in equine colic cases. VETERINARY JOURNAL, 171(1), 89-97. doi:10.1016/j.tvjl.2004.09.005

DOI
10.1016/j.tvjl.2004.09.005
Journal article

cis-Atracurium in dogs with and without porto-systemic shunts.

Adams, W. A., Mark Senior, J., Jones, R. S., Williams, J. M., & Gleed, R. D. (2006). cis-Atracurium in dogs with and without porto-systemic shunts.. Veterinary anaesthesia and analgesia, 33(1), 17-23. doi:10.1111/j.1467-2995.2005.00231.x

DOI
10.1111/j.1467-2995.2005.00231.x
Journal article

2005

Post-anaesthetic pulmonary oedema in horses: a review

Senior, M. (2005). Post-anaesthetic pulmonary oedema in horses: a review. VETERINARY ANAESTHESIA AND ANALGESIA, 32(4), 193-200. doi:10.1111/j.1467-2995.2005.00186.x

DOI
10.1111/j.1467-2995.2005.00186.x
Journal article

Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses

Barr, E. D., Clegg, P. D., Senior, J. M., & Singer, E. R. (2005). Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses. VETERINARY SURGERY, 34(2), 159-166. doi:10.1111/j.1532-950X.2005.00026.x

DOI
10.1111/j.1532-950X.2005.00026.x
Journal article

Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.

Barr, E. D., Clegg, P. D., Mark Senior, J., & Singer, E. R. (2005). Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.. Veterinary surgery : VS, 34(2), 159-166. doi:10.1111/j.1532-950x.2005.00026.x

DOI
10.1111/j.1532-950x.2005.00026.x
Journal article

Suspected venous air embolism in a horse.

Bradbury, L. A., Archer, D. C., Dugdale, A. H. A., Senior, J. M., & Edwards, G. B. (2005). Suspected venous air embolism in a horse.. The Veterinary record, 156(4), 109-111. doi:10.1136/vr.156.4.109

DOI
10.1136/vr.156.4.109
Journal article

'Cell structure, Basic tissue types and Composition of body fluids'- In Basic Anatomy and Physiology'

Senior, J. M. (2005). 'Cell structure, Basic tissue types and Composition of body fluids'- In Basic Anatomy and Physiology'. In K. Coumbe (Ed.), 'Equine Veterinary Nursing Manual' (pp. 25-74). Oxford: Blackwell Science Ltd.

Chapter

'The use of the non-depolarising neuromuscular blocking drug rocuronium administered by continuous infusion'

Alderson, B., Senior, J. M., Jones, R. S., & Dugdale, A. H. A. (2005). 'The use of the non-depolarising neuromuscular blocking drug rocuronium administered by continuous infusion'. Veterinary Anaesthesia and Analgesia, 32(3), 376.

Journal article

Intra-operative administration of dobutamine and/or phenylephrine does not increase peri- or post-operative mortality following equine colic surgery.

Langford, J., Dugdale, A. H. A., Senior, J. M., & Proudman, C. J. (2005). Intra-operative administration of dobutamine and/or phenylephrine does not increase peri- or post-operative mortality following equine colic surgery.. In L. Clark (Ed.), Association of Veterinary Anaesthetists Autumn conference 2005 (pp. 42). Suffolk: Animal Health Trust.

Conference Paper

2004

Retrospective study of the risk factors and prevalence of colic in horses after orthopaedic surgery

Senior, J. M., Pinchbeck, G. L., Dugdale, A. H. A., & Clegg, P. D. (2004). Retrospective study of the risk factors and prevalence of colic in horses after orthopaedic surgery. VETERINARY RECORD, 155(11), 321-+. doi:10.1136/vr.155.11.321

DOI
10.1136/vr.155.11.321
Journal article

'Cis-atracurium in dogs with portosystemic shunt'

Adams, W. A., Senior, J. M., Jones, R. S., Williams, J. M., & Gleed, R. D. (2004). 'Cis-atracurium in dogs with portosystemic shunt'. Veterinary Anaesthesia and Analgesia, 31(4), 17.

Journal article

2003

'Suspected Venous Air Embolism (VAE) Secondary to Catheter Misadventure'

Bradbury, L. A., Archer, D. C., Dugdale, A. H. A., Senior, J. M., & Edwards, G. B. (2003). 'Suspected Venous Air Embolism (VAE) Secondary to Catheter Misadventure'. Australian Equine Veterinarian, 22(2), 86-87.

Journal article

2002

Subluxation of the left elbow joint in a pony at induction of general anaesthesia

Senior, M., Smith, M., & Clegg, P. (2002). Subluxation of the left elbow joint in a pony at induction of general anaesthesia. VETERINARY RECORD, 151(6), 183-184. doi:10.1136/vr.151.6.183

DOI
10.1136/vr.151.6.183
Journal article

Postanaesthetic cerebral necrosis in five horses

McKay, J. S., Forest, T. W., Senior, M., Kelly, D. F., Jones, R. S., de Lahunta, A., & Summers, B. A. (2002). Postanaesthetic cerebral necrosis in five horses. VETERINARY RECORD, 150(3), 70-+. doi:10.1136/vr.150.3.70

DOI
10.1136/vr.150.3.70
Journal article

'Characterisation of equine C1-inhibitor protein using Western Blotting'

Senior, J. M., Marx, G., Edwards, G. B., Proudman, C. J., & Matthews, J. B. (2002). 'Characterisation of equine C1-inhibitor protein using Western Blotting'. International Colic Symposium Proceedings, 1, 137.

Journal article

Postanaesthetic cerebral necrosis in five horses - Comment

Senior, M., Jones, R. S., McKay, J., Kelly, D., Summers, B., de Lahunta, S., & Forest, T. (2002). Postanaesthetic cerebral necrosis in five horses - Comment. VETERINARY RECORD, 150(12), 388. Retrieved from https://www.webofscience.com/

Journal article

2001

Clinical use of atracurium in horses undergoing ophthalmic surgery.

Senior, J. M., Robinson, K. J., Dugdale, A., Price, C. M., Adams, W. A., & Jones, R. S. (2001). Clinical use of atracurium in horses undergoing ophthalmic surgery.. Veterinary anaesthesia and analgesia, 28(4), 207-208. doi:10.1046/j.1467-2987.2001.00064.x-i7

DOI
10.1046/j.1467-2987.2001.00064.x-i7
Journal article

Anatomy and Physiology

Clegg, P. D., Blake, C. L., Conwell, R. C., Hainisch, E., Newton, A., Post, E. M., . . . Wise, A. J. (2001). Anatomy and Physiology. In Unknown Book (pp. 25-73). Wiley. doi:10.1002/9780470690543.ch2

DOI
10.1002/9780470690543.ch2
Chapter

The use of the nondepolarizing neuromuscular blocking drug cis-atracurium in dogs.

Adams, W. A., Robinson, K. J., Mark Senior, J., & Jones, R. S. (2001). The use of the nondepolarizing neuromuscular blocking drug cis-atracurium in dogs.. Veterinary anaesthesia and analgesia, 28(3), 156-160. doi:10.1046/j.1467-2987.2001.00045.x

DOI
10.1046/j.1467-2987.2001.00045.x
Journal article

2000

'Assessment of atracurium besylate as an adjunct to general anaesthesia for ocular surgery in the horse'

Robinson, K. J., Adams, W. A., Senior, J. M., Dugdale, A. H. A., Laredo-Alvarez, F. L., Jones, R. S., & Knottenbelt, D. C. (2000). 'Assessment of atracurium besylate as an adjunct to general anaesthesia for ocular surgery in the horse'. Handbook of Presentations and Free Communications: 39th British Equine Veterinary Association Congress, 1, 200.

Journal article

'Clinical use of the nondepolarising muscle relaxant rocuronium (ORG 9426) in dogs'

Adams, W. A., Senior, J. M., Dugdale, A. H. A., Tute, A. S., Robinson, K. J., & Jones, R. S. (2000). 'Clinical use of the nondepolarising muscle relaxant rocuronium (ORG 9426) in dogs'. Proceedings of the 7th World Congress of Veterinary Anaesthesia, 1, 86.

Journal article