Research
Research grants
MECNUT: Impact of dietary exposure to emulsifiers on the intestinal mucosa - implications for inflammatory bowel disease and metabolic syndrome
MEDICAL RESEARCH COUNCIL
November 2017 - September 2021
Investigating bacteria-induced Wnt signalling as a mechanism for malignant development in the gut epithelium.
NORTH WEST CANCER RESEARCH FUND
September 2013 - September 2016
Evaluation of novel therapies targeting adhesive/invasive E.Coli
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
November 2007 - March 2012
Characterization of the endothelial cell surface molecule(s) responsible for galectin-3-induced secretion of metastasis-promoting cytokines
NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)
July 2014 - March 2017
Experiments to characterise the interaction between inflammatory bowel disease-related bacteria and mucosal glycoconjugates.
NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)
October 1999 - September 2002
The potential role of soluble plantain fibre and its components in preventing colonisation and invasion of the intestinal mucosa by S.Typhimurium.
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
October 2009 - December 2012
Prospective registry of inflammatory bowel diseases
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
September 2010 - August 2011
Mucosa-associated bacteria and human colon cancer.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
October 2005 - September 2007
Trial of antibiotics and hydroxychloroquine in Crohn's disease
NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)
October 2013 - March 2020
Bacterial oligomannan as a cause of intramucosal neutrophil dysfunction in Crohn's Disease.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
April 2001 - March 2003
Bacterial oligomannan as a cause of intramucosal neutrophil dysfunction in Chrohn's disease.
DIGESTIVE DISORDERS FOUNDATION
February 2001 - January 2003
Investigation into the mechanisms by which the galactose-binding lectin in mushrooms affects proliferation in colon cancer cells.
WORLD CANCER RESEARCH FUND (UK)
December 1999 - November 2002
Identification and functional characterization of the jacalin-binding cell membrane protein that regulates tyrosine phosphorylation of tumour suppressor PHAPI/pp32.
NORTH WEST CANCER RESEARCH FUND
October 2006 - September 2009
Tumour suppressing activity of Sclerotium rolfsii lectin on colon cancer
UK-INDIA EDUCATION AND RESEARCH INITIATIVE (UK)
January 2009 - December 2012
Cellular Biology of the Gastrointestinal Tract and Pancreas in Health and Disease.
MEDICAL RESEARCH COUNCIL
January 2000 - December 2004
Identifying the molecular mechanisms of interaction between colonic Crohn's disease mucosa-associated Escherichia coli and the intestinal epithelium
NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)
May 2008 - April 2010
Glycobiology: Interactions of Lectins with tumor cell surface molecule.
ASSOCIATION OF COMMONWEALTH UNIVERSITIES (UK)
October 2006 - April 2007
Studies to characterise the intracellular ligands for the anti-proliferative mushroom lectin in colon cancer cells.
NORTH WEST CANCER RESEARCH FUND
June 1999 - June 2002
Characterising the molecular mechanisms of Crohn's disease associated Escherichia coli that enable their survival and replication within the macrophage phagolysosome
MINISTRY OF HIGHER EDUCATION (LIBYA) 🚩
February 2013 - January 2016
Systems medicine of chronic inflammatory bowel disease (SysmedIBD)
EUROPEAN COMMISSION
December 2012 - November 2017
Mucins in the pathophysiology of inflammatory diseases of the bronchial and gastrointestinal epithelia.
MEDICAL RESEARCH COUNCIL
April 1998 - March 2001
Studies in inflammatory bowel disease.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
January 2002 - June 2002
The effects of dietry Gal-GalNAc-binding lectins on intestinal epithelial metabolism and proliferation.
BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL
December 1997 - May 2001
Investigation of IL-8 release by mucosally-adherent E. coli and bacteroides species relevant to pathogensis of inflammatory bowel disease.
NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)
September 2003 - September 2005
Macrophage dysfunction in the pathogenesis of Crohn's disease.
MEDICAL RESEARCH COUNCIL
February 2003 - January 2006
Cellular biology of the gastrointestinal tract and pancreas in health and disease.
MEDICAL RESEARCH COUNCIL
January 2005 - December 2009
The role of Adherent, Invasive Escherichia coli in the pathogenesis of Crohn's disease: Evaluation of new therapeutic approaches targeting E.coli replicating within the macrophage phagolysosome
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
April 2012 - March 2013
Assessment of the functional impact of Crohn's associated genetic polymorphisms
SHIRE PHARMACEUTICAL DEVELOPMENT INC (USA)
February 2012 - March 2013