Publications
Selected publications
- Asymmetric α-arylation of amino acids (Journal article - 2018)
- Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine (Journal article - 2013)
- Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance (Journal article - 2018)
- Triply Threaded [4]Rotaxanes (Journal article - 2016)
- Synthesis of Stable Thiazole-Linked Covalent Organic Frameworks via a Multicomponent Reaction. (Journal article - 2020)
2024
Autonomous mobile robots for exploratory synthetic chemistry.
Dai, T., Vijayakrishnan, S., Szczypiński, F. T., Ayme, J. -F., Simaei, E., Fellowes, T., . . . Cooper, A. I. (2024). Autonomous mobile robots for exploratory synthetic chemistry.. Nature, 635(8040), 890-897. doi:10.1038/s41586-024-08173-7
2D to 3D Reconstruction of Boron-Linked Covalent-Organic Frameworks.
Wang, X., Fellowes, T., Bahri, M., Qu, H., Li, B., Niu, H., . . . Cooper, A. I. (2024). 2D to 3D Reconstruction of Boron-Linked Covalent-Organic Frameworks.. Journal of the American Chemical Society, 146(20), 14128-14135. doi:10.1021/jacs.4c02673
2023
Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines
Morris, D. T. J., Wales, S. M., Echavarren, J., Zabka, M., Marsico, G., Ward, J. W., . . . Clayden, J. (2023). Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. doi:10.1021/jacs.3c06570
Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework
Shields, C. E., Wang, X., Fellowes, T., Clowes, R., Chen, L., Day, G. M., . . . Cooper, A. I. (2023). Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework. Angewandte Chemie, 135(34). doi:10.1002/ange.202303167
Frontispiece: Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework
Shields, C. E., Wang, X., Fellowes, T., Clowes, R., Chen, L., Day, G. M., . . . Cooper, A. I. (2023). Frontispiece: Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework. Angewandte Chemie International Edition, 62(34). doi:10.1002/anie.202383461
Frontispiz: Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework
Shields, C. E., Wang, X., Fellowes, T., Clowes, R., Chen, L., Day, G. M., . . . Cooper, A. I. (2023). Frontispiz: Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework. Angewandte Chemie, 135(34). doi:10.1002/ange.202383461
Experimental Confirmation of a Predicted Porous Hydrogen-bonded Organic Framework
Cooper, A., Little, M., Slater, A., Ward, J., Shields, C., Wang, X., . . . Clowes, R. (2023). Experimental Confirmation of a Predicted Porous Hydrogen-bonded Organic Framework. Angewandte Chemie International Edition. doi:10.1002/anie.202303167
2022
Discovery of a Covalent Triazine Framework Photocatalyst for Visible-Light-Driven Chemical Synthesis using High-Throughput Screening
Vijayakrishnan, S., Ward, J. W., & Cooper, A. I. (n.d.). Discovery of a Covalent Triazine Framework Photocatalyst for Visible-Light-Driven Chemical Synthesis using High-Throughput Screening. ACS Catalysis, 10057-10064. doi:10.1021/acscatal.2c02743
Accelerated Synthesis and Discovery of Covalent Organic Framework Photocatalysts for Hydrogen Peroxide Production
Zhao, W., Yan, P., Li, B., Bahri, M., Liu, L., Zhou, X., . . . Cooper, A. I. (2022). Accelerated Synthesis and Discovery of Covalent Organic Framework Photocatalysts for Hydrogen Peroxide Production. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 144(22), 9902-9909. doi:10.1021/jacs.2c02666
Accelerated Synthesis and Discovery of Covalent Organic Framework Photocatalysts for Hydrogen Peroxide Production
Using sound to synthesize covalent organic frameworks in water
Zhao, W., Yan, P., Yang, H., Bahri, M., James, A. M., Chen, H., . . . Cooper, A. I. (2022). Using sound to synthesize covalent organic frameworks in water. Nature Synthesis, 1(1), 87-95. doi:10.1038/s44160-021-00005-0
2021
A Cubic 3D Covalent Organic Framework with nbo Topology
Wang, X., Bahri, M., Fu, Z., Little, M. A., Liu, L., Niu, H., . . . Cooper, A. I. (2021). A Cubic 3D Covalent Organic Framework with nbo Topology. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 143(37), 15011-15016. doi:10.1021/jacs.1c08351
A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer.
Morris, D. T. J., Wales, S. M., Tilly, D. P., Farrar, E. H. E., Grayson, M. N., Ward, J. W., & Clayden, J. (2021). A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer.. Chem, 7(9), 2460-2472. doi:10.1016/j.chempr.2021.06.022
'Reverse biomimetic' synthesis of l-arogenate and its stabilized analogues from l-tyrosine
Eagling, L., Leonard, D. J., Schwarz, M., Urruzuno, I., Boden, G., Wailes, J. S., . . . Clayden, J. (2021). 'Reverse biomimetic' synthesis of l-arogenate and its stabilized analogues from l-tyrosine. CHEMICAL SCIENCE, 12(34), 11394-11398. doi:10.1039/d1sc03554a
Scalable synthesis and coupling of quaternary α-arylated amino acids: α-aryl substituents are tolerated in α-helical peptides
Leonard, D. J., Zieleniewski, F., Wellhofer, I., Baker, E. G., Ward, J. W., Woolfson, D. N., & Clayden, J. (2021). Scalable synthesis and coupling of quaternary α-arylated amino acids: α-aryl substituents are tolerated in α-helical peptides. CHEMICAL SCIENCE, 12(27), 9386-9390. doi:10.1039/d1sc01378e
Bottom-up wet-chemical synthesis of a two-dimensional porous carbon material with high supercapacitance using a cascade coupling/cyclization route
Xu, Y., Sprick, R. S., Brownbill, N. J., Blanc, F., Li, Q., Ward, J. W., . . . Cooper, A. I. (n.d.). Bottom-up wet-chemical synthesis of a two-dimensional porous carbon material with high supercapacitance using a cascade coupling/cyclization route. Journal of Materials Chemistry A, 9(6), 3303-3308. doi:10.1039/d0ta11649a
2020
Hydantoin-bridged medium ring scaffolds by migratory insertion of urea-tethered nitrile anions into aromatic C-N bonds
Millward, M. J., Ellis, E., Ward, J. W., & Clayden, J. (2021). Hydantoin-bridged medium ring scaffolds by migratory insertion of urea-tethered nitrile anions into aromatic C-N bonds. CHEMICAL SCIENCE, 12(6), 2091-2096. doi:10.1039/d0sc06188c
BIMP‐Catalyzed 1,3‐Prototropic Shift for the Highly Enantioselective Synthesis of Conjugated Cyclohexenones
Golec, J. C., Carter, E. M., Ward, J. W., Whittingham, W. G., Simon, L., Paton, R. S., & Dixon, D. J. (2020). BIMP‐Catalyzed 1,3‐Prototropic Shift for the Highly Enantioselective Synthesis of Conjugated Cyclohexenones. Angewandte Chemie International Edition. doi:10.1002/anie.202006202
Synthesis of Stable Thiazole-Linked Covalent Organic Frameworks via a Multicomponent Reaction.
Wang, K., Jia, Z., Bai, Y., Wang, X., Hodgkiss, S. E., Chen, L., . . . Cooper, A. I. (2020). Synthesis of Stable Thiazole-Linked Covalent Organic Frameworks via a Multicomponent Reaction.. Journal of the American Chemical Society, 142(25), 11131-11138. doi:10.1021/jacs.0c03418
2019
Amino Acid-Derived <i>trans</i>-<i>N</i>-Chloroformylimidazolidinones: Scalable, Stereoselective Synthesis, Structure, and Utility
Amer, M. M., Abas, H., Leonard, D. J., Ward, J. W., & Clayden, J. (2019). Amino Acid-Derived <i>trans</i>-<i>N</i>-Chloroformylimidazolidinones: Scalable, Stereoselective Synthesis, Structure, and Utility. JOURNAL OF ORGANIC CHEMISTRY, 84(11), 7199-7206. doi:10.1021/acs.joc.9b00727
Connective synthesis of 5,5-disubstituted hydantoins by tandem α-amination and α-arylation of silyl ketene acetals
Ward, J. W., Clayden, J., Saunthwal, R., Cornall, M., & Abrams, R. (2019). Connective synthesis of 5,5-disubstituted hydantoins by tandem α-amination and α-arylation of silyl ketene acetals. Chemical Science. doi:10.1039/C8SC05263H
2018
Substituted Dihydroisoquinolinones by Iodide-Promoted Cyclocarbonylation of Aromatic α-Amino Acids
Amer, M. M., Carrasco, A. C., Leonard, D. J., Ward, J. W., & Clayden, J. (2018). Substituted Dihydroisoquinolinones by Iodide-Promoted Cyclocarbonylation of Aromatic α-Amino Acids. ORGANIC LETTERS, 20(24), 7977-7981. doi:10.1021/acs.orglett.8b03551
Asymmetric α-arylation of amino acids
Leonard, D. J., Ward, J. W., & Clayden, J. (2018). Asymmetric α-arylation of amino acids. NATURE, 562(7725), 105-+. doi:10.1038/s41586-018-0553-9
Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance
Wechsel, R., Zabka, M., Ward, J. W., & Clayden, J. (2018). Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(10), 3528-3531. doi:10.1021/jacs.8b00567
2017
Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine
De Bo, G., Gall, M. A. Y., Kitching, M. O., Kuschel, S., Leigh, D. A., Tetlow, D. J., & Ward, J. W. (2017). Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(31), 10875-10879. doi:10.1021/jacs.7b05850
2016
Triply Threaded [4]Rotaxanes
Danon, J. J., Leigh, D. A., McGonigal, P. R., Ward, J. W., & Wu, J. (2016). Triply Threaded [4]Rotaxanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(38), 12643-12647. doi:10.1021/jacs.6b07733
Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas
Hall, J. E., Matlock, J. V., Ward, J. W., Gray, K. V., & Clayden, J. (2016). Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55(37), 11153-11157. doi:10.1002/anie.201605714
2014
Efficient Assembly of Threaded Molecular Machines for Sequence-Specific Synthesis
De Bo, G., Kuschel, S., Leigh, D. A., Lewandowski, B., Papmeyer, M., & Ward, J. W. (2014). Efficient Assembly of Threaded Molecular Machines for Sequence-Specific Synthesis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(15), 5811-5814. doi:10.1021/ja5022415
2013
Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine
Lewandowski, B., De Bo, G., Ward, J. W., Papmeyer, M., Kuschel, S., Aldegunde, M. J., . . . Leigh, D. A. (2013). Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine. SCIENCE, 339(6116), 189-193. doi:10.1126/science.1229753
2012
Expedient Construction of the [7-5-5] All-Carbon Tricyclic Core of the Daphniphyllum Alkaloids Daphnilongeranin B and Daphniyunnine D
Darses, B., Michaelides, I. N., Sladojevich, F., Ward, J. W., Rzepa, P. R., & Dixon, D. J. (2012). Expedient Construction of the [7-5-5] All-Carbon Tricyclic Core of the Daphniphyllum Alkaloids Daphnilongeranin B and Daphniyunnine D. ORGANIC LETTERS, 14(7), 1684-1687. doi:10.1021/ol3002267
2011
Expedient Route to the Functionalized Calyciphylline A-Type Skeleton via a Michael Addition-RCM Strategy
Sladojevich, F., Michaelides, I. N., Darses, B., Ward, J. W., & Dixon, D. J. (2011). Expedient Route to the Functionalized Calyciphylline A-Type Skeleton via a Michael Addition-RCM Strategy. ORGANIC LETTERS, 13(19), 5132-5135. doi:10.1021/ol202000w
2010
Construction of perhydro indol-2-ones by a methoxide catalyzed deacetylation-Michael-aldol cascade
Ward, J. W., Dodd, K., Rigby, C. L., De Savi, C., & Dixon, D. J. (2010). Construction of perhydro indol-2-ones by a methoxide catalyzed deacetylation-Michael-aldol cascade. CHEMICAL COMMUNICATIONS, 46(10), 1691-1693. doi:10.1039/b924637a
2008
Origin of Diastereocontrol in the Oxy-Michael Reactions of δ-Lactol Anions: A Computational and Experimental Study
Richardson, R. D., Hernandez-Juan, F. A., Ward, J. W., & Dixon, D. J. (2008). Origin of Diastereocontrol in the Oxy-Michael Reactions of δ-Lactol Anions: A Computational and Experimental Study. CHEMISTRY-A EUROPEAN JOURNAL, 14(31), 9607-9612. doi:10.1002/chem.200801368
Highly stereoselective oxy-Michael additions to β,γ-unsaturated α-keto esters:: Rapid enantioselective synthesis of 3-hydroxybutenolides
Xiong, X., Ovens, C., Pilling, A. W., Ward, J. W., & Dixon, D. J. (2008). Highly stereoselective oxy-Michael additions to β,γ-unsaturated α-keto esters:: Rapid enantioselective synthesis of 3-hydroxybutenolides. ORGANIC LETTERS, 10(4), 565-567. doi:10.1021/ol702693m