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2024

Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones via aryne chemistry.

Figueroa, L. P. R., de Carvalho, R. L., Almeida, R. G., Paz, E. R. S., Diogo, E. B. T., Araujo, M. H., . . . da Silva Júnior, E. N. (2024). Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones via aryne chemistry.. RSC Med Chem. doi:10.1039/d4md00558a

DOI
10.1039/d4md00558a
Journal article

An Aza-Enolate Strategy Enables Iridium-Catalyzed Enantioselective Hydroalkenylations of Minimally Polarized Alkenes en Route to Complex N-Aryl β<sup>2</sup>-Amino Acids.

Hong, F., Robertson, C. M., & Bower, J. F. (2024). An Aza-Enolate Strategy Enables Iridium-Catalyzed Enantioselective Hydroalkenylations of Minimally Polarized Alkenes en Route to Complex N-Aryl β<sup>2</sup>-Amino Acids.. Journal of the American Chemical Society. doi:10.1021/jacs.4c07519

DOI
10.1021/jacs.4c07519
Journal article

1,3,5,7-Tetramethyl-8-phenyl-2,4,6-trioxa-8-phosphatricyclo[3.3.1.13,7]decane

Adams, R., Pringle, P., & Bower, J. (2024). 1,3,5,7-Tetramethyl-8-phenyl-2,4,6-trioxa-8-phosphatricyclo[3.3.1.13,7]decane. In Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rn02530

DOI
10.1002/047084289X.rn02530
Chapter

2023

C-C Bond Activations of Minimally Activated Cyclopropanes

Sokolova, O. O., Dalling, A. G., & Bower, J. F. (2023). C-C Bond Activations of Minimally Activated Cyclopropanes. SYNLETT, 34(12), 1317-1326. doi:10.1055/s-0042-1753177

DOI
10.1055/s-0042-1753177
Journal article

2022

Atom and step economical synthesis of acyclic quaternary centers <i>via</i> iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes

Cooper, P., Dalling, A. G., Farrar, E. H. E., Aldhous, T. P., Grelaud, S., Lester, E., . . . Bower, J. F. (2022). Atom and step economical synthesis of acyclic quaternary centers <i>via</i> iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes. CHEMICAL SCIENCE, 13(37), 11183-11189. doi:10.1039/d2sc02790a

DOI
10.1039/d2sc02790a
Journal article

2021

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades

Jones, B. T., Garcia-Carceles, J., Caiger, L., Hazelden, I. R., Lewis, R. J., Langer, T., & Bower, J. F. (2021). Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 143(38), 15593-15598. doi:10.1021/jacs.1c08615

DOI
10.1021/jacs.1c08615
Journal article

Naphthoquinones and Derivatives for Chemotherapy: Perspectives and Limitations of their Anti-trypanosomatids Activities

Dantas-Pereira, L., Cunha-Junior, E. F., Andrade-Neto, V. V., Bower, J. F., Jardim, G. A. M., da Silva, E. N. J., . . . Menna-Barreto, R. F. S. (2021). Naphthoquinones and Derivatives for Chemotherapy: Perspectives and Limitations of their Anti-trypanosomatids Activities. CURRENT PHARMACEUTICAL DESIGN, 27(15), 1807-1824. doi:10.2174/1381612826666201109111802

DOI
10.2174/1381612826666201109111802
Journal article

2020

Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi

Wood, J. M., Satam, N. S., Almeida, R. G., Cristani, V. S., de Lima, D. P., Dantas-Pereira, L., . . . da Silva Júnior, E. N. (2020). Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi. Bioorganic and Medicinal Chemistry, 28(15). doi:10.1016/j.bmc.2020.115565

DOI
10.1016/j.bmc.2020.115565
Journal article

Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Henderson, A. S., Bower, J. F., & Galan, M. C. (2020). Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination. ORGANIC & BIOMOLECULAR CHEMISTRY, 18(16), 3012-3016. doi:10.1039/d0ob00155d

DOI
10.1039/d0ob00155d
Journal article

Oxidative Addition of Alkenyl and Alkynyl Iodides to a Au<SUP>I</SUP> Complex

Cadge, J. A., Sparkes, H. A., Bower, J. F., & Russell, C. A. (2020). Oxidative Addition of Alkenyl and Alkynyl Iodides to a Au<SUP>I</SUP> Complex. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(16), 6617-6621. doi:10.1002/anie.202000473

DOI
10.1002/anie.202000473
Journal article

Rhodacyclopentanones as Linchpins for the Atom Economical Assembly of Diverse Polyheterocycles

Wang, G. -W., Boyd, O., Young, T. A., Bertrand, S. M., & Bower, J. F. (2020). Rhodacyclopentanones as Linchpins for the Atom Economical Assembly of Diverse Polyheterocycles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(4), 1740-1745. doi:10.1021/jacs.9b12421

DOI
10.1021/jacs.9b12421
Journal article

Rh-Catalyzed [2+2+2] Cycloadditions with Benzoquinones: De Novo Access to Naphthoquinones for Lignan and Type II Polyketide Synthesis

Wood, J. M., da Silva Junior, E. N., & Bower, J. F. (2020). Rh-Catalyzed [2+2+2] Cycloadditions with Benzoquinones: De Novo Access to Naphthoquinones for Lignan and Type II Polyketide Synthesis. ORGANIC LETTERS, 22(1), 265-269. doi:10.1021/acs.orglett.9b04266

DOI
10.1021/acs.orglett.9b04266
Journal article

2019

Modular Access to Eight-Membered N-Heterocycles by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes

Boyd, O., Wang, G. -W., Sokolova, O. O., Calow, A. D. J., Bertrand, S. M., & Bower, J. F. (2019). Modular Access to Eight-Membered N-Heterocycles by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(52), 18844-18848. doi:10.1002/anie.201910276

DOI
10.1002/anie.201910276
Journal article

Rhodium(I)‐Catalyzed Reductive Carbon–Carbon Bond Formation

Calow, A. D. J., & Bower, J. F. (2019). Rhodium(I)‐Catalyzed Reductive Carbon–Carbon Bond Formation. In Unknown Book (pp. 133-160). Wiley. doi:10.1002/9783527811908.ch7

DOI
10.1002/9783527811908.ch7
Chapter

Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines

Ma, X., Hazelden, I. R., Langer, T., Munday, R. H., & Bower, J. F. (2019). Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 141(8), 3356-3360. doi:10.1021/jacs.8b12689

DOI
10.1021/jacs.8b12689
Journal article

Carbonylative C-C Bond Activation of Electron-Poor Cyclopropanes: Rhodium-Catalyzed (3+1+2) Cycloadditions of Cyclopropylamides

Dalling, A. G., Yamauchi, T., McCreanor, N. G., Cox, L., & Bower, J. F. (2019). Carbonylative C-C Bond Activation of Electron-Poor Cyclopropanes: Rhodium-Catalyzed (3+1+2) Cycloadditions of Cyclopropylamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(1), 221-225. doi:10.1002/anie.201811460

DOI
10.1002/anie.201811460
Journal article

2018

Stereospecific Alkene Aziridination Using a Bifunctional Amino-Reagent: An Aza-Prilezhaev Reaction

Farndon, J. J., Young, T. A., & Bower, J. F. (2018). Stereospecific Alkene Aziridination Using a Bifunctional Amino-Reagent: An Aza-Prilezhaev Reaction. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(51), 17846-17850. doi:10.1021/jacs.8b10485

DOI
10.1021/jacs.8b10485
Journal article

Iridium-Catalyzed α-Selective Arylation of Styrenes by Dual C-H Functionalization

Cooper, P., Crisenza, G. E. M., Feron, L. J., & Bower, J. F. (2018). Iridium-Catalyzed α-Selective Arylation of Styrenes by Dual C-H Functionalization. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(43), 14198-14202. doi:10.1002/anie.201808299

DOI
10.1002/anie.201808299
Journal article

Synthesis of Nitrogen Heterocycles <i>via</i> Directed Carbonylative C-C Bond Activation of Cyclopropanes

Dalling, A. G., & Bower, J. F. (2018). Synthesis of Nitrogen Heterocycles <i>via</i> Directed Carbonylative C-C Bond Activation of Cyclopropanes. CHIMIA, 72(9), 595-600. doi:10.2533/chimia.2018.595

DOI
10.2533/chimia.2018.595
Journal article

Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C-H Oxidative Addition

Grelaud, S., Cooper, P., Feron, L. J., & Bower, J. F. (2018). Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C-H Oxidative Addition. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(30), 9351-9356. doi:10.1021/jacs.8b04627

DOI
10.1021/jacs.8b04627
Journal article

Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of <i>N</i>-(Pentafluorobenzoyloxy)carbamates

Hazelden, I. R., Carmona, R. C., Langer, T., Pringle, P. G., & Bower, J. F. (2018). Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of <i>N</i>-(Pentafluorobenzoyloxy)carbamates. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(18), 5124-5128. doi:10.1002/anie.201801109

DOI
10.1002/anie.201801109
Journal article

Oxidative Addition, Transmetalation, and Reductive Elimination at a 2,2 '-Bipyridyl-Ligated Gold Center

Harper, M. J., Arthur, C. J., Crosby, J., Emmett, E. J., Falconer, R. L., Fensham-Smith, A. J., . . . Russell, C. A. (2018). Oxidative Addition, Transmetalation, and Reductive Elimination at a 2,2 '-Bipyridyl-Ligated Gold Center. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(12), 4440-4445. doi:10.1021/jacs.8b01411

DOI
10.1021/jacs.8b01411
Journal article

Modular Access to Azepines by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes

Wang, G. -W., & Bower, J. F. (2018). Modular Access to Azepines by Directed Carbonylative C-C Bond Activation of Aminocyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(8), 2743-2747. doi:10.1021/jacs.7b13087

DOI
10.1021/jacs.7b13087
Journal article

2017

A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents

Ma, X., Farndon, J. J., Young, T. A., Fey, N., & Bower, J. F. (2017). A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(46), 14531-14535. doi:10.1002/anie.201708176

DOI
10.1002/anie.201708176
Journal article

A Simple and Broadly Applicable C−N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents

Ma, X., Farndon, J. J., Young, T. A., Fey, N., & Bower, J. F. (2017). A Simple and Broadly Applicable C−N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino Reagents. Angewandte Chemie, 129(46), 14723-14727. doi:10.1002/ange.201708176

DOI
10.1002/ange.201708176
Journal article

Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy

Buxton, C. S., Blakemore, D. C., & Bower, J. F. (2017). Reductive Coupling of Acrylates with Ketones and Ketimines by a Nickel-Catalyzed Transfer-Hydrogenative Strategy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(44), 13824-13828. doi:10.1002/anie.201707531

DOI
10.1002/anie.201707531
Journal article

Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent

Farndon, J. J., Ma, X., & Bower, J. F. (2017). Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(40), 14005-14008. doi:10.1021/jacs.7b07830

DOI
10.1021/jacs.7b07830
Journal article

Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation

Harper, M. J., Emmett, E. J., Bower, J. F., & Russell, C. A. (2017). Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(36), 12386-12389. doi:10.1021/jacs.7b06668

DOI
10.1021/jacs.7b06668
Journal article

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-<i>Trypanosoma cruzi</i> activities and electrochemical studies of functionalized quinones

Jardim, G. A. M., Silva, T. L., Goulart, M. O. F., de Simone, C. A., Barbosa, J. M. C., Salomao, K., . . . da Silva Junior, E. N. (2017). Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-<i>Trypanosoma cruzi</i> activities and electrochemical studies of functionalized quinones. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 136, 406-419. doi:10.1016/j.ejmech.2017.05.011

DOI
10.1016/j.ejmech.2017.05.011
Journal article

Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles

Race, N. J., Hazelden, I. R., Faulkner, A., & Bower, J. F. (2017). Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles. CHEMICAL SCIENCE, 8(8), 5248-5260. doi:10.1039/c7sc01480e

DOI
10.1039/c7sc01480e
Journal article

Recent Methodologies That Exploit C-C Single-Bond Cleavage of Strained Ring Systems by Transition Metal Complexes

Fumagalli, G., Stanton, S., & Bower, J. F. (2017). Recent Methodologies That Exploit C-C Single-Bond Cleavage of Strained Ring Systems by Transition Metal Complexes. CHEMICAL REVIEWS, 117(13), 9404-9432. doi:10.1021/acs.chemrev.6b00599

DOI
10.1021/acs.chemrev.6b00599
Journal article

Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters

Race, N. J., Faulkner, A., Fumagalli, G., Yamauchi, T., Scott, J. S., Ryden-Landergren, M., . . . Bower, J. F. (2017). Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters. CHEMICAL SCIENCE, 8(3), 1981-1985. doi:10.1039/c6sc04466b

DOI
10.1039/c6sc04466b
Journal article

2016

New Initiation Modes for Directed Carbonylative C-C Bond Activation: Rhodium-Catalyzed (3+1+2) Cycloadditions of Aminomethylcyclopropanes

Wang, G. -W., McCreanor, N. G., Shaw, M. H., Whittingham, W. G., & Bower, J. F. (2016). New Initiation Modes for Directed Carbonylative C-C Bond Activation: Rhodium-Catalyzed (3+1+2) Cycloadditions of Aminomethylcyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(41), 13501-13504. doi:10.1021/jacs.6b08608

DOI
10.1021/jacs.6b08608
Journal article

Synthesis and applications of rhodacyclopentanones derived from C-C bond activation

Shaw, M. H., & Bower, J. F. (2016). Synthesis and applications of rhodacyclopentanones derived from C-C bond activation. CHEMICAL COMMUNICATIONS, 52(72), 10817-10829. doi:10.1039/c6cc04359c

DOI
10.1039/c6cc04359c
Journal article

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation

Jardim, G. A. M., Bower, J. F., & da Silva Junior, E. N. (2016). Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation. ORGANIC LETTERS, 18(18), 4454-4457. doi:10.1021/acs.orglett.6b01586

DOI
10.1021/acs.orglett.6b01586
Journal article

Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones

McCreanor, N. G., Stanton, S., & Bower, J. F. (2016). Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(36), 11465-11468. doi:10.1021/jacs.6b07046

DOI
10.1021/jacs.6b07046
Journal article

Diverse <i>N</i>-Heterocyclic Ring Systems via Aza-Heck Cyclizations of <i>N</i>-(Pentafluorobenzoyloxy)sulfonamides

Hazelden, I. R., Ma, X., Langer, T., & Bower, J. F. (2016). Diverse <i>N</i>-Heterocyclic Ring Systems via Aza-Heck Cyclizations of <i>N</i>-(Pentafluorobenzoyloxy)sulfonamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55(37), 11198-11202. doi:10.1002/anie.201605152

DOI
10.1002/anie.201605152
Journal article

C2-Alkenylation of N-heteroaromatic compounds <i>via</i> Bronsted acid catalysis

Crisenza, G. E. M., Dauncey, E. M., & Bower, J. F. (2016). C2-Alkenylation of N-heteroaromatic compounds <i>via</i> Bronsted acid catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 14(24), 5820-5825. doi:10.1039/c6ob00705h

DOI
10.1039/c6ob00705h
Journal article

Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system

Shaw, M. H., Whittingham, W. G., & Bower, J. E. (2016). Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system. TETRAHEDRON, 72(22), 2731-2741. doi:10.1016/j.tet.2015.08.052

DOI
10.1016/j.tet.2015.08.052
Journal article

Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives

Jardim, G. A. M., da Silva Junior, E. N., & Bower, J. F. (2016). Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives. CHEMICAL SCIENCE, 7(6), 3780-3784. doi:10.1039/c6sc00302h

DOI
10.1039/c6sc00302h
Journal article

Editorial

Bower, J., Hansson, P., & Karton, A. (2016). Editorial. Chemical Data Collections, 2, A1-A2. doi:10.1016/j.cdc.2016.07.002

DOI
10.1016/j.cdc.2016.07.002
Journal article

Carbohydrates as enantioinduction components in stereoselective catalysis

Henderson, A. S., Bower, J. F., & Galan, M. C. (2016). Carbohydrates as enantioinduction components in stereoselective catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 14(17), 4008-4017. doi:10.1039/c6ob00368k

DOI
10.1039/c6ob00368k
Journal article

Dichotomous mechanistic behavior in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals

Race, N. J., Faulkner, A., Shaw, M. H., & Bower, J. F. (2016). Dichotomous mechanistic behavior in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals. CHEMICAL SCIENCE, 7(2), 1508-1513. doi:10.1039/c5sc04037j

DOI
10.1039/c5sc04037j
Journal article

Branch Selective Mural-type Alkene Hydroarylation Reactions

Crisenza, G. E. M., & Bower, J. F. (2016). Branch Selective Mural-type Alkene Hydroarylation Reactions. CHEMISTRY LETTERS, 45(1), 2-9. doi:10.1246/cl.150913

DOI
10.1246/cl.150913
Journal article

Catalytic chirality generation: new strategies for heterocyclic chemistry

Bower, J. (2016). Catalytic chirality generation: new strategies for heterocyclic chemistry. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 252. Retrieved from https://www.webofscience.com/

Conference Paper

2015

Branch-Selective Alkene Hydroarylation by Cooperative Destabilization: Iridium-Catalyzed <i>ortho</i>-Alkylation of Acetanilides

Crisenza, G. E. M., Sokolova, O. O., & Bower, J. F. (2015). Branch-Selective Alkene Hydroarylation by Cooperative Destabilization: Iridium-Catalyzed <i>ortho</i>-Alkylation of Acetanilides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 54(49), 14866-14870. doi:10.1002/anie.201506581

DOI
10.1002/anie.201506581
Journal article

ChemInform Abstract: An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2‐Amino‐Acylation, ‐Carboxylation, ‐Arylation, ‐Vinylation, and ‐Alkynylation.

Faulkner, A., Scott, J. S., & Bower, J. F. (2015). ChemInform Abstract: An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2‐Amino‐Acylation, ‐Carboxylation, ‐Arylation, ‐Vinylation, and ‐Alkynylation.. ChemInform, 46(46). doi:10.1002/chin.201546136

DOI
10.1002/chin.201546136
Journal article

Nucleophilic Aromatic Substitution (S<sub>N</sub>Ar) as an Approach to Challenging Carbohydrate-Aryl Ethers

Henderson, A. S., Medina, S., Bower, J. F., & Galan, M. C. (2015). Nucleophilic Aromatic Substitution (S<sub>N</sub>Ar) as an Approach to Challenging Carbohydrate-Aryl Ethers. ORGANIC LETTERS, 17(19), 4846-4849. doi:10.1021/acs.orglett.5b02413

DOI
10.1021/acs.orglett.5b02413
Journal article

Modular Access to Substituted Azocanes via a Rhodium-Catalyzed Cycloaddition-Fragmentation Strategy

Shaw, M. H., Croft, R. A., Whittingham, W. G., & Bower, J. F. (2015). Modular Access to Substituted Azocanes via a Rhodium-Catalyzed Cycloaddition-Fragmentation Strategy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(25), 8054-8057. doi:10.1021/jacs.5b05215

DOI
10.1021/jacs.5b05215
Journal article

An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2-Amino-Acylation, -Carboxylation, -Arylation, -Vinylation, and -Alkynylation

Faulkner, A., Scott, J. S., & Bower, J. F. (2015). An Umpolung Approach to Alkene Carboamination: Palladium Catalyzed 1,2-Amino-Acylation, -Carboxylation, -Arylation, -Vinylation, and -Alkynylation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(22), 7224-7230. doi:10.1021/jacs.5b03732

DOI
10.1021/jacs.5b03732
Journal article

Stereoselective synthesis of glycosides using (salen)Co catalysts as promoters

Medina, S., Henderson, A. S., Bower, J. F., & Galan, M. C. (2015). Stereoselective synthesis of glycosides using (salen)Co catalysts as promoters. CHEMICAL COMMUNICATIONS, 51(43), 8939-8941. doi:10.1039/c5cc02552d

DOI
10.1039/c5cc02552d
Journal article

Reversible C-C Bond Activation Enables Stereocontrol in Rh-Catalyzed Carbonylative Cycloadditions of Aminocyclopropanes

Shaw, M. H., McCreanor, N. G., Whittingham, W. G., & Bower, J. F. (2015). Reversible C-C Bond Activation Enables Stereocontrol in Rh-Catalyzed Carbonylative Cycloadditions of Aminocyclopropanes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(1), 463-468. doi:10.1021/ja511335v

DOI
10.1021/ja511335v
Journal article

2014

Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis

Henderson, A. S., Bower, J. F., & Galan, M. C. (2014). Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis. ORGANIC & BIOMOLECULAR CHEMISTRY, 12(45), 9180-9183. doi:10.1039/c4ob02056a

DOI
10.1039/c4ob02056a
Journal article

Branch-Selective, Iridium-Catalyzed Hydroarylation of Monosubstituted Alkenes via a Cooperative Destabilization Strategy

Crisenza, G. E. M., McCreanor, N. G., & Bower, J. F. (2014). Branch-Selective, Iridium-Catalyzed Hydroarylation of Monosubstituted Alkenes via a Cooperative Destabilization Strategy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(29), 10258-10261. doi:10.1021/ja505776m

DOI
10.1021/ja505776m
Journal article

Copper catalyzed Heck-like cyclizations of oxime esters

Faulkner, A., Race, N. J., Scott, J. S., & Bower, J. F. (2014). Copper catalyzed Heck-like cyclizations of oxime esters. CHEMICAL SCIENCE, 5(6), 2416-2421. doi:10.1039/c4sc00652f

DOI
10.1039/c4sc00652f
Journal article

2013

Palladium Catalyzed Cyclizations of Oxime Esters with 1,2-Disubstituted Alkenes: Synthesis of Dihydropyrroles

Race, N. J., & Bower, J. F. (2013). Palladium Catalyzed Cyclizations of Oxime Esters with 1,2-Disubstituted Alkenes: Synthesis of Dihydropyrroles. ORGANIC LETTERS, 15(17), 4616-4619. doi:10.1021/ol4023112

DOI
10.1021/ol4023112
Journal article

Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N-Heterobicyclic Enones

Shaw, M. H., Melikhova, E. Y., Kloer, D. P., Whittingham, W. G., & Bower, J. F. (2013). Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N-Heterobicyclic Enones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135(13), 4992-4995. doi:10.1021/ja401936c

DOI
10.1021/ja401936c
Journal article

A Robust First-Pass Protocol for the Heck-Mizoroki Reaction

Murray, P. M., Bower, J. F., Cox, D. K., Galbraith, E. K., Parker, J. S., & Sweeney, J. B. (2013). A Robust First-Pass Protocol for the Heck-Mizoroki Reaction. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 17(3), 397-405. doi:10.1021/op300364p

DOI
10.1021/op300364p
Journal article

Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of α,α-disubstituted dihydropyrroles and studies towards an asymmetric protocol

Faulkner, A., Scott, J. S., & Bower, J. F. (2013). Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of α,α-disubstituted dihydropyrroles and studies towards an asymmetric protocol. CHEMICAL COMMUNICATIONS, 49(15), 1521-1523. doi:10.1039/c2cc38944d

DOI
10.1039/c2cc38944d
Journal article

Catalytic chirality generation: new strategies for <i>N</i>-heterocyclic chemistry

Bower, J. F. (2013). Catalytic chirality generation: new strategies for <i>N</i>-heterocyclic chemistry. In JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS Vol. 56 (pp. 55). Retrieved from https://www.webofscience.com/

Conference Paper

2012

Olefin cross-metathesis for the synthesis of heteroaromatic compounds

Donohoe, T. J., Bower, J. F., & Chan, L. K. M. (2012). Olefin cross-metathesis for the synthesis of heteroaromatic compounds. ORGANIC & BIOMOLECULAR CHEMISTRY, 10(7), 1322-1328. doi:10.1039/c2ob06659a

DOI
10.1039/c2ob06659a
Journal article

Highly Efficient Narasaka-Heck Cyclizations Mediated by P(3,5-(CF3)2C6H3)3: Facile Access to N-Heterobicyclic Scaffolds

Faulkner, A., & Bower, J. F. (2012). Highly Efficient Narasaka-Heck Cyclizations Mediated by P(3,5-(CF3)2C6H3)3: Facile Access to N-Heterobicyclic Scaffolds. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(7), 1675-1679. doi:10.1002/anie.201107511

DOI
10.1002/anie.201107511
Journal article

2011

Synthesis of 2,4,6-trisubstituted pyridines <i>via</i> an olefin cross-metathesis/Heck-cyclisation-elimination sequence

Donohoe, T. J., Bower, J. F., Baker, D. B., Basutto, J. A., Chan, L. K. M., & Gallagher, P. (2011). Synthesis of 2,4,6-trisubstituted pyridines <i>via</i> an olefin cross-metathesis/Heck-cyclisation-elimination sequence. CHEMICAL COMMUNICATIONS, 47(38), 10611-10613. doi:10.1039/c1cc14257g

DOI
10.1039/c1cc14257g
Journal article

Heteroaromatic Synthesis <i>via</i> Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines

Donohoe, T. J., Basutto, J. A., Bower, J. F., & Rathi, A. (2011). Heteroaromatic Synthesis <i>via</i> Olefin Cross-Metathesis: Entry to Polysubstituted Pyridines. ORGANIC LETTERS, 13(5), 1036-1039. doi:10.1021/ol103088r

DOI
10.1021/ol103088r
Journal article

Formation of C-C Bonds via Iridium-Catalyzed Hydrogenation and Transfer Hydrogenation

Bower, J. F., & Krische, M. J. (2011). Formation of C-C Bonds via Iridium-Catalyzed Hydrogenation and Transfer Hydrogenation. IRIDIUM CATALYSIS, 34, 107-138. doi:10.1007/978-3-642-15334-1_5

DOI
10.1007/978-3-642-15334-1_5
Journal article

2010

Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants

Donohoe, T. J., Bower, J. F., & Basutto, J. A. (2010). Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants. NATURE PROTOCOLS, 5(12), 2005-2010. doi:10.1038/nprot.2010.147

DOI
10.1038/nprot.2010.147
Journal article

Substituted Pyrroles via Olefin Cross-Metathesis

Donohoe, T. J., Race, N. J., Bower, J. F., & Callens, C. K. A. (2010). Substituted Pyrroles via Olefin Cross-Metathesis. ORGANIC LETTERS, 12(18), 4094-4097. doi:10.1021/ol101681r

DOI
10.1021/ol101681r
Journal article

<i>N</i>-Heterocycle construction <i>via</i> cyclic sulfamidates. Applications in synthesis

Bower, J. F., Rujirawanicha, J., & Gallagher, T. (2010). <i>N</i>-Heterocycle construction <i>via</i> cyclic sulfamidates. Applications in synthesis. ORGANIC & BIOMOLECULAR CHEMISTRY, 8(7), 1505-1519. doi:10.1039/b921842d

DOI
10.1039/b921842d
Journal article

An expedient route to substituted furans via olefin cross-metathesis

Donohoe, T. J., & Bower, J. F. (2010). An expedient route to substituted furans via olefin cross-metathesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(8), 3373-3376. doi:10.1073/pnas.0913466107

DOI
10.1073/pnas.0913466107
Journal article

2009

Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines

Donohoe, T. J., Bower, J. F., Basutto, J. A., Fishlock, L. P., Procopiou, P. A., & Callens, C. K. A. (2009). Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines. TETRAHEDRON, 65(44), 8969-8980. doi:10.1016/j.tet.2009.07.076

DOI
10.1016/j.tet.2009.07.076
Journal article

Synthesis of substituted pyridines and pyridazines <i>via</i> ring closing metathesis

Donohoe, T. J., Fishlock, L. P., Basutto, J. A., Bower, J. F., Procopiou, P. A., & Thompson, A. L. (2009). Synthesis of substituted pyridines and pyridazines <i>via</i> ring closing metathesis. CHEMICAL COMMUNICATIONS, (21), 3008-3010. doi:10.1039/b904363b

DOI
10.1039/b904363b
Journal article

Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents

Bower, J. F., Kim, I. S., Patman, R. L., & Krische, M. J. (2009). Catalytic Carbonyl Addition through Transfer Hydrogenation: A Departure from Preformed Organometallic Reagents. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(1), 34-46. doi:10.1002/anie.200802938

DOI
10.1002/anie.200802938
Journal article

2008

Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition

Patman, R. L., Bower, J. F., Kim, I. S., & Krische, M. J. (2008). Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition. ALDRICHIMICA ACTA, 41(4), 95-104. Retrieved from https://www.webofscience.com/

Journal article

Kepner-Tregoe Decision Analysis as a Tool To Aid Route Selection. Part 3. Application to a Back-Up Series of Compounds in the PDK Project

Parker, J. S., Bower, J. F., Murray, P. M., Patel, B., & Talavera, P. (2008). Kepner-Tregoe Decision Analysis as a Tool To Aid Route Selection. Part 3. Application to a Back-Up Series of Compounds in the PDK Project. ORGANIC PROCESS RESEARCH & DEVELOPMENT, 12(6), 1060-1077. doi:10.1021/op8000355

DOI
10.1021/op8000355
Journal article

Diene Hydroacylation from the Alcohol or Aldehyde Oxidation Level via Ruthenium-Catalyzed C-C Bond-Forming Transfer Hydrogenation: Synthesis of β,γ-Unsaturated Ketones

Shibahara, F., Bower, J. F., & Krische, M. J. (2008). Diene Hydroacylation from the Alcohol or Aldehyde Oxidation Level via Ruthenium-Catalyzed C-C Bond-Forming Transfer Hydrogenation: Synthesis of β,γ-Unsaturated Ketones. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(43), 14120-14122. doi:10.1021/ja805356j

DOI
10.1021/ja805356j
Journal article

Carbonyl propargylation from the alcohol or aldehyde oxidation level employing 1,3-enynes as surrogates to preformed allenylmetal reagents: A ruthenium-catalyzed C-C bond-forming transfer hydrogenation

Patman, R. L., Williams, V. M., Bower, J. F., & Krische, M. J. (2008). Carbonyl propargylation from the alcohol or aldehyde oxidation level employing 1,3-enynes as surrogates to preformed allenylmetal reagents: A ruthenium-catalyzed C-C bond-forming transfer hydrogenation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(28), 5220-5223. doi:10.1002/anie.200801359

DOI
10.1002/anie.200801359
Journal article

Ruthenium-catalyzed C-C bond forming transfer hydrogenation: Carbonyl allylation from the alcohol or aldehyde oxidation level employing acyclic 1,3-dienes as surrogates to preformed allyl metal reagents

Shibahara, F., Bower, J. F., & Krische, M. J. (2008). Ruthenium-catalyzed C-C bond forming transfer hydrogenation: Carbonyl allylation from the alcohol or aldehyde oxidation level employing acyclic 1,3-dienes as surrogates to preformed allyl metal reagents. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(20), 6338-+. doi:10.1021/ja801213x

DOI
10.1021/ja801213x
Journal article

Iridium-catalyzed C-C coupling via transfer hydrogenation: Carbonyl addition from the alcohol or aldehyde oxidation level employing 1,3-cyclohexadiene

Bower, J. F., Patman, R. L., & Krische, M. J. (2008). Iridium-catalyzed C-C coupling via transfer hydrogenation: Carbonyl addition from the alcohol or aldehyde oxidation level employing 1,3-cyclohexadiene. ORGANIC LETTERS, 10(5), 1033-1035. doi:10.1021/ol800159w

DOI
10.1021/ol800159w
Journal article

2007

Catalytic C-C coupling via transfer hydrogenation: Reverse prenylation, crotylation, and allylation from the alcohol or aldehyde oxidation level

Bower, J. F., Skucas, E., Patman, R. L., & Krische, M. J. (2007). Catalytic C-C coupling via transfer hydrogenation: Reverse prenylation, crotylation, and allylation from the alcohol or aldehyde oxidation level. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(49), 15134-+. doi:10.1021/ja077389b

DOI
10.1021/ja077389b
Journal article

Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines. ORGANIC LETTERS, 9(23), 4909-4912. doi:10.1021/ol7022104

DOI
10.1021/ol7022104
Journal article

Carbonyl allylation in the absence of preformed allyl metal reagents: Reverse Prenylation via iridium-catalyzed hydrogenative coupling of dimethylallene

Skucas, E., Bower, J. F., & Krische, M. J. (2007). Carbonyl allylation in the absence of preformed allyl metal reagents: Reverse Prenylation via iridium-catalyzed hydrogenative coupling of dimethylallene. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(42), 12678-+. doi:10.1021/ja075971u

DOI
10.1021/ja075971u
Journal article

Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates:: synthesis and applications of α-phosphono lactams

Bower, J. F., Williams, A. J., Woodward, H. L., Szeto, P., Lawrence, R. M., & Gallagher, T. (2007). Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates:: synthesis and applications of α-phosphono lactams. ORGANIC & BIOMOLECULAR CHEMISTRY, 5(16), 2636-2644. doi:10.1039/b706315f

DOI
10.1039/b706315f
Journal article

Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates. Synthesis of levofloxacin

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates. Synthesis of levofloxacin. ORGANIC LETTERS, 9(17), 3283-3286. doi:10.1021/ol0712475

DOI
10.1021/ol0712475
Journal article

Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin

Bower, J. F., Riis-Johannessen, T., Szeto, P., Whitehead, A. J., & Gallagher, T. (2007). Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin. CHEMICAL COMMUNICATIONS, (7), 728-730. doi:10.1039/b617260a

DOI
10.1039/b617260a
Journal article

Cyclic sulfamidates as versatile lactam precursors. An evaluation of synthetic strategies towards (-)-aphanorphine

Bower, J. F., Szeto, P., & Gallagher, T. (2007). Cyclic sulfamidates as versatile lactam precursors. An evaluation of synthetic strategies towards (-)-aphanorphine. ORGANIC & BIOMOLECULAR CHEMISTRY, 5(1), 143-150. doi:10.1039/b614999e

DOI
10.1039/b614999e
Journal article

2006

Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams

Bower, J. F., Chakthong, S., Svenda, J., Williams, A. J., Lawrence, R. M., Szeto, P., & Gallagher, T. (2006). Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams. ORGANIC & BIOMOLECULAR CHEMISTRY, 4(10), 1868-1877. doi:10.1039/b601804a

DOI
10.1039/b601804a
Journal article

2005

Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine

Bower, J. F., Szeto, P., & Gallagher, T. (2005). Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine. CHEMICAL COMMUNICATIONS, (46), 5793-5795. doi:10.1039/b510761j

DOI
10.1039/b510761j
Journal article

2004

Cyclic sulfamidates as vehicles for the synthesis of substituted lactams

Bower, J. F., Svenda, J., Williams, A. J., Charmant, J. P. H., Lawrence, R. M., Szeto, P., & Gallagher, T. (2004). Cyclic sulfamidates as vehicles for the synthesis of substituted lactams. ORGANIC LETTERS, 6(25), 4727-4730. doi:10.1021/ol048036+

DOI
10.1021/ol048036+
Journal article

2003

Praseodymium complexes of 2,2′-bipyridine;: the crystal and molecular structures of Pr(bipy)<sub>3</sub>(NCS)<sub>3</sub>, Pr(bipy)<sub>2</sub>(NO<sub>3</sub>)<sub>3</sub>, Pr(bipy)<sub>2</sub>Cl<sub>3</sub>(OH<sub>2</sub>)•EtOH and Pr(bipy)(S<sub>2</sub>CNEt<sub>2</sub>)<sub>3</sub>

Bower, J. F., Cotton, S. A., Fawcett, J., Hughes, R. S., & Russell, D. R. (2003). Praseodymium complexes of 2,2′-bipyridine;: the crystal and molecular structures of Pr(bipy)<sub>3</sub>(NCS)<sub>3</sub>, Pr(bipy)<sub>2</sub>(NO<sub>3</sub>)<sub>3</sub>, Pr(bipy)<sub>2</sub>Cl<sub>3</sub>(OH<sub>2</sub>)•EtOH and Pr(bipy)(S<sub>2</sub>CNEt<sub>2</sub>)<sub>3</sub>. POLYHEDRON, 22(2), 347-354. doi:10.1016/S0277-5387(02)01359-1

DOI
10.1016/S0277-5387(02)01359-1
Journal article