Publications
2024
Geographical migration and fitness dynamics of Streptococcus pneumoniae.
Belman, S., Lefrancq, N., Nzenze, S., Downs, S., du Plessis, M., Lo, S. W., . . . Salje, H. (2024). Geographical migration and fitness dynamics of Streptococcus pneumoniae.. Nature, 631(8020), 386-392. doi:10.1038/s41586-024-07626-3
Development and external validation of the ‘Global Surgical-Site Infection’ (GloSSI) predictive model in adult patients undergoing gastrointestinal surgery
KA, M., SR, K., N, C., A, A., A, A., M, A. -A., . . . C, C. (2024). Development and external validation of the ‘Global Surgical-Site Infection’ (GloSSI) predictive model in adult patients undergoing gastrointestinal surgery. British Journal of Surgery, 111(6). doi:10.1093/bjs/znae129
Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.
Heinz, E., Pearse, O., Zuza, A., Bilima, S., Msefula, C., Musicha, P., . . . Feasey, N. A. (2024). Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.. Genome medicine, 16(1), 67. doi:10.1186/s13073-024-01342-3
Azithromycin for Bacterial Watery Diarrhea: A Reanalysis of the AntiBiotics for Children With Severe Diarrhea (ABCD) Trial Incorporating Molecular Diagnostics.
Pavlinac, P. B., Platts-Mills, J. A., Liu, J., Atlas, H. E., Gratz, J., Operario, D., . . . AntiBiotics for Children with severe Diarrhea (ABCD) Study Group. (2024). Azithromycin for Bacterial Watery Diarrhea: A Reanalysis of the AntiBiotics for Children With Severe Diarrhea (ABCD) Trial Incorporating Molecular Diagnostics.. The Journal of infectious diseases, 229(4), 988-998. doi:10.1093/infdis/jiad252
<i>Shigella</i> Detection and Molecular Serotyping With a Customized TaqMan Array Card in the Enterics for Global Health (EFGH): <i>Shigella</i> Surveillance Study.
Liu, J., Garcia Bardales, P. F., Islam, K., Jarju, S., Juma, J., Mhango, C., . . . Houpt, E. R. (2024). <i>Shigella</i> Detection and Molecular Serotyping With a Customized TaqMan Array Card in the Enterics for Global Health (EFGH): <i>Shigella</i> Surveillance Study.. Open forum infectious diseases, 11(Suppl 1), S34-S40. doi:10.1093/ofid/ofad574
Data Management in Multicountry Consortium Studies: The Enterics For Global Health (EFGH) <i>Shigella</i> Surveillance Study Example.
Feutz, E., Biswas, P. K., Ndeketa, L., Ogwel, B., Onwuchekwa, U., Sarwar, G., . . . Galagan, S. R. (2024). Data Management in Multicountry Consortium Studies: The Enterics For Global Health (EFGH) <i>Shigella</i> Surveillance Study Example.. Open forum infectious diseases, 11(Suppl 1), S48-S57. doi:10.1093/ofid/ofad573
Diarrhea Case Surveillance in the Enterics for Global Health <i>Shigella</i> Surveillance Study: Epidemiologic Methods.
Atlas, H. E., Conteh, B., Islam, M. T., Jere, K. C., Omore, R., Sanogo, D., . . . Pavlinac, P. B. (2024). Diarrhea Case Surveillance in the Enterics for Global Health <i>Shigella</i> Surveillance Study: Epidemiologic Methods.. Open forum infectious diseases, 11(Suppl 1), S6-S16. doi:10.1093/ofid/ofad664
Evaluation of Fecal Inflammatory Biomarkers to Identify Bacterial Diarrhea Episodes: Systematic Review and Protocol for the Enterics for Global Health <i>Shigella</i> Surveillance Study.
Babb, C., Badji, H., Bhuiyan, M. T. R., Cornick, J., Qureshi, S., Sonye, C., . . . Rogawski McQuade, E. T. (2024). Evaluation of Fecal Inflammatory Biomarkers to Identify Bacterial Diarrhea Episodes: Systematic Review and Protocol for the Enterics for Global Health <i>Shigella</i> Surveillance Study.. Open forum infectious diseases, 11(Suppl 1), S65-S75. doi:10.1093/ofid/ofad652
Exploring Natural Immune Responses to <i>Shigella</i> Exposure Using Multiplex Bead Assays on Dried Blood Spots in High-Burden Countries: Protocol From a Multisite Diarrhea Surveillance Study.
Benedicto-Matambo, P., Avolio, L. N., Badji, H., Batool, R., Khanam, F., Munga, S., . . . Platts-Mills, J. A. (2024). Exploring Natural Immune Responses to <i>Shigella</i> Exposure Using Multiplex Bead Assays on Dried Blood Spots in High-Burden Countries: Protocol From a Multisite Diarrhea Surveillance Study.. Open forum infectious diseases, 11(Suppl 1), S58-S64. doi:10.1093/ofid/ofad650
Microbiological Methods Used in the Enterics for Global Health <i>Shigella</i> Surveillance Study.
Horne, B., Badji, H., Bhuiyan, M. T. R., Romaina Cachique, L., Cornick, J., Hotwani, A., . . . Tennant, S. M. (2024). Microbiological Methods Used in the Enterics for Global Health <i>Shigella</i> Surveillance Study.. Open forum infectious diseases, 11(Suppl 1), S25-S33. doi:10.1093/ofid/ofad576
The Enterics for Global Health (EFGH) <i>Shigella</i> Surveillance Study in Malawi.
Mategula, D., Ndalama, M., Lefu, C., Chinkhumba, J., Ndeketa, L., Munthali, V., . . . Cornick, J. (2024). The Enterics for Global Health (EFGH) <i>Shigella</i> Surveillance Study in Malawi.. Open forum infectious diseases, 11(Suppl 1), S101-S106. doi:10.1093/ofid/ofae050
2023
The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi.
Obolski, U., Swarthout, T. D., Kalizang'oma, A., Mwalukomo, T. S., Chan, J. M., Weight, C. M., . . . Heyderman, R. S. (2023). The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi.. Nature communications, 14(1), 7477. doi:10.1038/s41467-023-43160-y
Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries.
NIHR Global Health Research Unit on Global Surgery Collaborators. (2023). Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries.. BJA open, 7, 100207. doi:10.1016/j.bjao.2023.100207
Use of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review With Meta-analysis.
NIHR Global Health Research Unit on Global Surgery, GlobalSurg Collaborative. (2023). Use of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review With Meta-analysis.. Annals of surgery, 277(6), e1331-e1347. doi:10.1097/sla.0000000000005506
Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protocol.
Singleton, D., Ibarz-Pavon, A., Swarthout, T. D., Bonomali, F., Cornick, J., Kalizang'oma, A., . . . Heyderman, R. S. (2023). Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protocol.. BMJ Open, 13(5), e069560. doi:10.1136/bmjopen-2022-069560
A global genomic perspective on the multidrug- resistant<i> Streptococcus</i><i> pneumoniae</i> 15A-CC63 sub- lineage following pneumococcal conjugate vaccine introduction
Hawkins, P. A., Chochua, S., Lo, S. W., Belman, S., Antonio, M., Kwambana-Adams, B., . . . McGee, L. (n.d.). A global genomic perspective on the multidrug- resistant<i> Streptococcus</i><i> pneumoniae</i> 15A-CC63 sub- lineage following pneumococcal conjugate vaccine introduction. Microbial Genomics, 9(4). doi:10.1099/mgen.0.000998
Utilizing river and wastewater as a SARS-CoV-2 surveillance tool to predict trends and identify variants of concern in settings with limited formal sewage systems.
Different clinical features in Malawian outpatients presenting with COVID-19 prior to and during Omicron variant dominance: A prospective observational study.
Chibwana, M. G., Thole, H. W., Anscombe, C., Ashton, P. M., Green, E., Barnes, K. G., . . . Jambo, K. C. (2023). Different clinical features in Malawian outpatients presenting with COVID-19 prior to and during Omicron variant dominance: A prospective observational study.. PLOS global public health, 3(3), e0001575. doi:10.1371/journal.pgph.0001575
A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study
Anscombe, C., Lissauer, S., Thole, H., Rylance, J., Dula, D., Menyere, M., . . . Ashton, P. M. (2023). A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study. BMC INFECTIOUS DISEASES, 23(1). doi:10.1186/s12879-022-07941-y
Pan-genome study underlining the extent of genomic variation of invasive<i>Streptococcus pneumoniae</i>in Malawi
2022
Emergence of a multidrug-resistant and virulent <i>Streptococcus pneumoniae</i> lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study
Lo, S. W., Mellor, K., Cohen, R., Alonso, A. R., Belman, S., Kumar, N., . . . Varon, E. (2022). Emergence of a multidrug-resistant and virulent <i>Streptococcus pneumoniae</i> lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study. LANCET MICROBE, 3(10), E735-E743. doi:10.1016/S2666-5247(22)00158-6
Global economic burden of unmet surgical need for appendicitis.
Reuter, A., Rogge, L., Monahan, M., Kachapila, M., Morton, D. G., Davies, J., . . . NIHR Global Surgery Collaboration. (2022). Global economic burden of unmet surgical need for appendicitis.. The British journal of surgery, 109(10), 995-1003. doi:10.1093/bjs/znac195
A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV
Ndlangisa, K. M., du Plessis, M., Lo, S., de Gouveia, L., Chaguza, C., Antonio, M., . . . Con, G. P. S. (2022). A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV. MICROBIAL GENOMICS, 8(4). doi:10.1099/mgen.0.000746
Comparative Genomics of Disease and Carriage Serotype 1 Pneumococci
Chaguza, C., Ebruke, C., Senghore, M., Lo, S. W., Tientcheu, P. -E., Gladstone, R. A., . . . Bentley, S. D. (2022). Comparative Genomics of Disease and Carriage Serotype 1 Pneumococci. GENOME BIOLOGY AND EVOLUTION, 14(4). doi:10.1093/gbe/evac052
International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease.
Gladstone, R. A., Siira, L., Brynildsrud, O. B., Vestrheim, D. F., Turner, P., Clarke, S. C., . . . Global Pneumococcal Sequencing Consortium. (2022). International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease.. Vaccine, 40(7), 1054-1060. doi:10.1016/j.vaccine.2021.10.046
Prevalence of nasopharyngeal <i>Streptococcus pneumoniae</i> carriage and resistance to macrolides in the setting of azithromycin mass drug administration: analysis from a cluster-randomised controlled trial in Malawi, 2015-17
Hart, J. D., Samikwa, L., Meleke, H., Burr, S. E., Cornick, J., Kalua, K., & Bailey, R. L. (2022). Prevalence of nasopharyngeal <i>Streptococcus pneumoniae</i> carriage and resistance to macrolides in the setting of azithromycin mass drug administration: analysis from a cluster-randomised controlled trial in Malawi, 2015-17. LANCET MICROBE, 3(2), E142-E150. doi:10.1016/S2666-5247(21)00279-2
2021
Effect of 3 Days of Oral Azithromycin on Young Children With Acute Diarrhea in Low-Resource Settings A Randomized Clinical Trial
Ahmed, T., Chisti, M. J., Rahman, M. W., Alam, T., Ahmed, D., Parvin, I., . . . Ashorn, P. (2021). Effect of 3 Days of Oral Azithromycin on Young Children With Acute Diarrhea in Low-Resource Settings A Randomized Clinical Trial. JAMA NETWORK OPEN, 4(12). doi:10.1001/jamanetworkopen.2021.36726
Emergence of a multidrug resistant and virulent <i>Streptococcus pneumoniae</i> lineage mediates serotype replacement after PCV13
Genomic investigation of a suspected Klebsiella pneumoniae outbreak in a neonatal care unit in sub- Saharan Africa
Cornick, J., Musicha, P., Peno, C., Seager, E., Tam, P. -Y. I., Bilima, S., . . . Cain, A. K. (2021). Genomic investigation of a suspected Klebsiella pneumoniae outbreak in a neonatal care unit in sub- Saharan Africa. MICROBIAL GENOMICS, 7(11). doi:10.1099/mgen.0.000703
Editorial: Secondary Effects of Antibiotic Exposure
Cain, A. K., Nolan, L. M., Cornick, J., & Hassan, K. A. (2021). Editorial: Secondary Effects of Antibiotic Exposure. FRONTIERS IN MICROBIOLOGY, 12. doi:10.3389/fmicb.2021.737958
The metabolic, virulence and antimicrobial resistance profiles of colonizing <i>Streptococcus pneumoniae</i> shift after pneumococcal vaccine introduction in urban Malawi
Gori, A., Obolski, U., Swarthout, T., Lourenço, J., Weight, C., Cornick, J., . . . Heyderman, R. (2021). The metabolic, virulence and antimicrobial resistance profiles of colonizing <i>Streptococcus pneumoniae</i> shift after pneumococcal vaccine introduction in urban Malawi. doi:10.1101/2021.07.21.21260914
The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci.
D'Aeth, J. C., van der Linden, M. P., McGee, L., de Lencastre, H., Turner, P., Song, J. -H., . . . GPS Consortium. (2021). The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci.. eLife, 10, e67113. doi:10.7554/elife.67113
Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa
Morton, B., Barnes, K. G., Anscombe, C., Jere, K., Matambo, P., Mandolo, J., . . . Jambo, K. C. (2021). Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-23267-w
Whole genome sequence analysis of<i> Shigella</i> from Malawi identifies fluoroquinolone resistance
Stenhouse, G. E., Jere, K. C., Peno, C., Bengtsson, R. J., Chinyama, E., Mandolo, J., . . . Baker, K. S. (2021). Whole genome sequence analysis of<i> Shigella</i> from Malawi identifies fluoroquinolone resistance. MICROBIAL GENOMICS, 7(5). doi:10.1099/mgen.0.000532
Changes in Invasive Pneumococcal Disease Caused by <i>Streptococcus pneumoniae</i> Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project
Bennett, J. C., Hetrich, M. K., Quesada, M. G., Sinkevitch, J. N., Knoll, M. D., Feikin, D. R., . . . Hayford, K. (2021). Changes in Invasive Pneumococcal Disease Caused by <i>Streptococcus pneumoniae</i> Serotype 1 following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project. MICROORGANISMS, 9(4). doi:10.3390/microorganisms9040696
In depth analysis of patients with severe SARS-CoV-2 in sub-Saharan Africa demonstrates distinct clinical and immunological profiles.
Whole genomic comparative analysis of <i>Streptococcus pneumoniae</i> serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, Morocco
Nzoyikorera, N., Diawara, I., Fresia, P., Maaloum, F., Katfy, K., Nayme, K., . . . Elmdaghri, N. (2021). Whole genomic comparative analysis of <i>Streptococcus pneumoniae</i> serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, Morocco. BMC GENOMICS, 22(1). doi:10.1186/s12864-020-07316-0
2020
Whole genomic comparative analysis of Streptococcus pneumoniae serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, Morocco
Whole genomic comparative analysis of Streptococcus pneumoniae serotype 1 isolates causing invasive and non-invasive infections among children under 5 years in Casablanca, Morocco
Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
Drake, T. M., Pata, F., Ghosh, D., Ademuyiwa, A. O., Arnaud, A., Bhangu, A., . . . Rajan, R. (2020). Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study. BMJ GLOBAL HEALTH, 5(12). doi:10.1136/bmjgh-2020-003429
First case report of a successfully managed severe COVID-19 infection in Malawi
Banda, N. P., Hara, W., Cocker, D., Musasa, S., Burke, R. M., Brown, C., . . . Morton, B. (2020). First case report of a successfully managed severe COVID-19 infection in Malawi. MALAWI MEDICAL JOURNAL, 32(4), 124-126. doi:10.4314/mmj.v32i4.8
First case report of a successfully managed severe COVID-19 infection in Malawi.
Banda, N. P., Hara, W., Cocker, D., Musasa, S., Burke, R. M., Brown, C., . . . Morton, B. (2020). First case report of a successfully managed severe COVID-19 infection in Malawi.. Malawi medical journal : the journal of Medical Association of Malawi, 32(4), 226-228. doi:10.4314/mmj.v32i4.8
Whole genome sequence analysis of <i>Shigella</i> from Malawi identifies fluoroquinolone resistance
Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism
Chaguza, C., Yang, M., Cornick, J. E., du Plessis, M., Gladstone, R. A., Kwambana-Adams, B. A., . . . Bentley, S. D. (2020). Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism. COMMUNICATIONS BIOLOGY, 3(1). doi:10.1038/s42003-020-01290-9
Genomic Characteristics of Invasive Streptococcus pneumoniae Serotype 1 in New Caledonia Prior to the Introduction of PCV13
Hanachi, M., Kiran, A., Cornick, J., Harigua-Souiai, E., Everett, D., Benkahla, A., & Souiai, O. (2020). Genomic Characteristics of Invasive Streptococcus pneumoniae Serotype 1 in New Caledonia Prior to the Introduction of PCV13. Bioinformatics and Biology Insights, 14, 117793222096210. doi:10.1177/1177932220962106
Whole Genomic Comparative Analysis of Streptococcus Pneumoniae Serotype 1 Isolates Causing Invasive and Non-Invasive Infections Among Children Under 5 years in Casablanca, Morocco
Genomic investigation of a suspected multi-drug resistant<i>Klebsiella pneumoniae</i>outbreak in a neonatal care unit in sub-Saharan Africa
Extended effect of short-course azithromycin for the treatment of diarrhoea in children on antimicrobial resistance in nasopharyngeal and intestinal bacteria: Study Protocol for the antimicrobial resistance sub-study of the multicountry AntiBiotics for Children with Diarrhea (ABCD) trial
Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates
Gladstone, R. A., Lo, S. W., Goater, R., Yeats, C., Taylor, B., Hadfield, J., . . . Bentley, S. D. (2020). Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates. MICROBIAL GENOMICS, 6(5). doi:10.1099/mgen.0.000357
Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data
Chaguza, C., Heinsbroek, E., Gladstone, R., Tafatatha, T., Alaerts, M., Peno, C., . . . Bentley, S. (2020). Early Signals of Vaccine-driven Perturbation Seen in Pneumococcal Carriage Population Genomic Data. Clinical Infectious Diseases, 70(7), 1294-1303. doi:10.1093/cid/ciz404
A mosaic tetracycline resistance gene <i>tet</i>(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa
Lo, S. W., Gladstone, R. A., van Tonder, A. J., Du Plessis, M., Cornick, J. E., Hawkins, P. A., . . . von Gottberg, A. (2020). A mosaic tetracycline resistance gene <i>tet</i>(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75(3), 512-520. doi:10.1093/jac/dkz477
2019
A novel mosaic tetracycline resistance gene <i>tet</i>(S/M) detected in a multidrug-resistant pneumococcal CC230 lineage that underwent capsular switching in South Africa
Emerging Resistance to Empiric Antimicrobial Regimens for Pediatric Bloodstream Infections in Malawi (1998–2017)
Iroh Tam, P. -Y., Musicha, P., Kawaza, K., Cornick, J., Denis, B., Freyne, B., . . . Heyderman, R. (2019). Emerging Resistance to Empiric Antimicrobial Regimens for Pediatric Bloodstream Infections in Malawi (1998–2017). Clinical Infectious Diseases, 69(1), 61-68. doi:10.1093/cid/ciy834
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study
Lo, S. W., Gladstone, R. A., van Tonder, A. J., Lees, J. A., du Plessis, M., Benisty, R., . . . Urban, Y. (2019). Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study. LANCET INFECTIOUS DISEASES, 19(7), 759-769. doi:10.1016/S1473-3099(19)30297-X
Putative novel <i>cps</i> loci in a large global collection of pneumococci
van Tonder, A. J., Gladstone, R. A., Lo, S. W., Nahm, M. H., du Plessis, M., Cornick, J., . . . Bentley, S. D. (2019). Putative novel <i>cps</i> loci in a large global collection of pneumococci. MICROBIAL GENOMICS, 5(7). doi:10.1099/mgen.0.000274
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
Bhangu, A. (2019). Global variation in anastomosis and end colostomy formation following left-sided colorectal resection. BJS OPEN, 3(3), 403-414. doi:10.1002/bjs5.50138
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact
Gladstone, R. A., Lo, S. W., Lees, J. A., Croucher, N. J., van Tonder, A. J., Corander, J., . . . Bentley, S. D. (2019). International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact. EBIOMEDICINE, 43, 338-346. doi:10.1016/j.ebiom.2019.04.021
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
Thomas, H. S., Weiser, T. G., Drake, T. M., Knight, S. R., Fairfield, C., Ademuyiwa, A. O., . . . Blanco, R. (2019). Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy. BRITISH JOURNAL OF SURGERY, 106(2), E103-E112. doi:10.1002/bjs.11051
2018
Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data
Chaguza, C., Heinsbroek, E., Gladstone, R., Tafatatha, T., Alaerts, M., Peno, C., . . . Bentley, S. (n.d.). Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data. BioRxiv. doi:10.1101/459693
Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci
Azarian, T., Mitchell, P. K., Georgieva, M., Thompson, C. M., Ghouila, A., Pollard, A. J., . . . Hanage, W. P. (2018). Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci. PLOS PATHOGENS, 14(11). doi:10.1371/journal.ppat.1007438
Epidemiological and Molecula Characterization of an Invasive Group A Streptococcus <i>emm</i>32.2 Outbreak (vol 55, pg 1837, 2017)
Cornick, J. E., Kiran, A. M., Vivancos, R., Van Aartsen, J., Clarke, J., Bevan, E., . . . Everett, D. B. (2018). Epidemiological and Molecula Characterization of an Invasive Group A Streptococcus <i>emm</i>32.2 Outbreak (vol 55, pg 1837, 2017). JOURNAL OF CLINICAL MICROBIOLOGY, 56(9). doi:10.1128/JCM.01001-18
Corrigendum: SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data.
Epping, L., van Tonder, A. J., Gladstone, R. A., Bentley, S. D., Page, A. J., Keane, J. A., & The Global Pneumococcal Sequencing Consortium. (2018). Corrigendum: SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data.. Microbial genomics, 4(8). doi:10.1099/mgen.0.000204
Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine.
Lo, S. W., Gladstone, R. A., van Tonder, A. J., Hawkins, P. A., Kwambana-Adams, B., Cornick, J. E., . . . Bentley, S. D. (2018). Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine.. Journal of clinical microbiology, 56(7), e00228-e00218. doi:10.1128/jcm.00228-18
Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
Bhangu, A., Ademuyiwa, A. O., Aguilera, M. L., Alexander, P., Al-Saqqa, S. W., Borda-Luque, G., . . . Blanco, R. (2018). Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study. LANCET INFECTIOUS DISEASES, 18(5), 516-525. doi:10.1016/S1473-3099(18)30101-4
2017
Comparative genomic analysis and in vivo modelling of Streptococcus pneumoniae ST3081 and ST618 isolates reveal key genetic and phenotypic differences contributing to clonal replacement of serotype 1 in The Gambia.
Bricio-Moreno, L., Ebruke, C., Chaguza, C., Cornick, J., Kwambana-Adams, B., Yang, M., . . . Kadioglu, A. (2017). Comparative genomic analysis and in vivo modelling of Streptococcus pneumoniae ST3081 and ST618 isolates reveal key genetic and phenotypic differences contributing to clonal replacement of serotype 1 in The Gambia.. The Journal of infectious diseases, 216(10), 1318-1327. doi:10.1093/infdis/jix472
Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study
Musicha, P., Cornick, J. E., Bar-Zeev, N., French, N., Masesa, C., Denis, B., . . . Feasey, N. A. (2017). Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study. LANCET INFECTIOUS DISEASES, 17(10), 1042-1052. doi:10.1016/S1473-3099(17)30394-8
Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi
Chaguza, C., Cornick, J. E., Andam, C. P., Gladstone, R. A., Alaerts, M., Musicha, P., . . . Everett, D. B. (2017). Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi. VACCINE, 35(35), 4594-4602. doi:10.1016/j.vaccine.2017.07.009
Determining the worldwide epidemiology of surgical site infections after gastrointestinal resection surgery: protocol for a multicentre, international, prospective cohort study (GlobalSurg 2)
Khatri, C., Mohan, M., Drake, T. M., Glasbey, J., Nepogodiev, D., Shaw, C., . . . Collaborative, G. (2017). Determining the worldwide epidemiology of surgical site infections after gastrointestinal resection surgery: protocol for a multicentre, international, prospective cohort study (GlobalSurg 2). BMJ OPEN, 7(7). doi:10.1136/bmjopen-2016-012150
Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus emm32.2 Outbreak
Cornick, J. E., Kiran, A. M., Vivancos, R., Van Aartsen, J., Clarke, J., Bevan, E., . . . Everett, D. B. (n.d.). Epidemiological and Molecular Characterization of an Invasive Group A Streptococcus emm32.2 Outbreak. Journal of Clinical Microbiology, 55(6), 1837-1846. doi:10.1128/JCM.00191-17
The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1
Cornick, J. E., Bishop, O. T., Yalcin, F., Kiran, A. M., Kumwenda, B., Chaguza, C., . . . Consortium, P. (2017). The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1. VACCINE, 35(6), 972-980. doi:10.1016/j.vaccine.2016.12.037
2016
Understanding pneumococcal serotype 1 biology through population genomic analysis
Chaguza, C., Cornick, J. E., Harris, S. R., Andam, C. P., Bricio-Moreno, L., Yang, M., . . . Bentley, S. D. (2016). Understanding pneumococcal serotype 1 biology through population genomic analysis. BMC INFECTIOUS DISEASES, 16. doi:10.1186/s12879-016-1987-z
Recombination in <i>Streptococcus pneumoniae</i> Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule
Chaguza, C., Andam, C. P., Harris, S. R., Cornick, J. E., Yang, M., Bricio-Moreno, L., . . . Hanage, W. P. (2016). Recombination in <i>Streptococcus pneumoniae</i> Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule. MBIO, 7(5). doi:10.1128/mBio.01053-16
Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013
du Plessis, M., Allam, M., Tempia, S., Wolter, N., de Gouveia, L., von Mollendorf, C., . . . von Gottberg, A. (2016). Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013. JOURNAL OF CLINICAL MICROBIOLOGY, 54(5), 1326-1334. doi:10.1128/JCM.00055-16
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa
Mulder, N. J., Adebiyi, E., Alami, R., Benkahla, A., Brandful, J., Doumbia, S., . . . Ulenga, N. (2016). H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. GENOME RESEARCH, 26(2), 271-277. doi:10.1101/gr.196295.115
2015
Region-specific diversification of the highly virulent serotype 1 <i>Streptococcus pneumoniae</i>
Cornick, J. E., Chaguza, C., Harris, S. R., Yalcin, F., Senghore, M., Kiran, A. M., . . . Everett, D. B. (2015). Region-specific diversification of the highly virulent serotype 1 <i>Streptococcus pneumoniae</i>. MICROBIAL GENOMICS, 1(2). doi:10.1099/mgen.0.000027
High multiple carriage and emergence of <i>Streptococcus pneumoniae</i> vaccine serotype variants in Malawian children
Kamng'ona, A. W., Hinds, J., Bar-Zeev, N., Gould, K. A., Chaguza, C., Msefula, C., . . . Everett, D. B. (2015). High multiple carriage and emergence of <i>Streptococcus pneumoniae</i> vaccine serotype variants in Malawian children. BMC INFECTIOUS DISEASES, 15. doi:10.1186/s12879-015-0980-2
Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome
Kulohoma, B. W., Cornick, J. E., Chaguza, C., Yalcin, F., Harris, S. R., Gray, K. J., . . . Heyderman, R. S. (2015). Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome. INFECTION AND IMMUNITY, 83(10), 4165-4173. doi:10.1128/IAI.00814-15
Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome (vol 83, pg 4165, 2015)
Kulohoma, B. W., Cornick, J. E., Chaguza, C., Yalcin, F., Harris, S. R., Gray, K. J., . . . Heyderman, R. S. (2015). Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome (vol 83, pg 4165, 2015). INFECTION AND IMMUNITY, 83(12), 4896. doi:10.1128/IAI.01156-15
Mechanisms and impact of genetic recombination in the evolution of <i>Streptococcus pneumoniae</i>
Chaguza, C., Cornick, J. E., & Everett, D. B. (2015). Mechanisms and impact of genetic recombination in the evolution of <i>Streptococcus pneumoniae</i>. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 13, 241-247. doi:10.1016/j.csbj.2015.03.007
2014
Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst <i>Streptococcus pneumoniae</i> in Malawi
Cornick, J. E., Harris, S. R., Parry, C. M., Moore, M. J., Jassi, C., Kamng'ona, A., . . . Everett, D. B. (2014). Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst <i>Streptococcus pneumoniae</i> in Malawi. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69(2), 368-374. doi:10.1093/jac/dkt384
Elucidation of the pathogenesis of pneumococcal meningitis in a nasopharynx-to-meninges translocation mouse model
Yang, M., Engel, H., Clauzier, L., Riley, L., Pottinger, S., Cornick, J., . . . Kadioglu, A. (2014). Elucidation of the pathogenesis of pneumococcal meningitis in a nasopharynx-to-meninges translocation mouse model. IMMUNOLOGY, 143, 165. Retrieved from https://www.webofscience.com/
2013
Piliation of Invasive <i>Streptococcus pneumoniae</i> Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi
Kulohoma, B. W., Gray, K., Kamng'ona, A., Cornick, J., Bentley, S. D., Heyderman, R. S., & Everett, D. B. (2013). Piliation of Invasive <i>Streptococcus pneumoniae</i> Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi. CLINICAL AND VACCINE IMMUNOLOGY, 20(11), 1729-1735. doi:10.1128/CVI.00403-13
Novel approach towards the development of vaccine candidates against pneumococcal meningitis
Yang, M., Engel, H., Chaguza, C., Cornick, J., Hathaway, L., Everett, D., & Kadioglu, A. (2013). Novel approach towards the development of vaccine candidates against pneumococcal meningitis. In IMMUNOLOGY Vol. 140 (pp. 201). Retrieved from https://www.webofscience.com/
2012
Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach
Everett, D. B., Cornick, J., Denis, B., Chewapreecha, C., Croucher, N., Harris, S., . . . Bentley, S. D. (2012). Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach. PLOS ONE, 7(9). doi:10.1371/journal.pone.0044250
Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides.
Cornick, J. E., & Bentley, S. D. (2012). Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides.. Microbes and infection, 14(7-8), 573-583. doi:10.1016/j.micinf.2012.01.012
Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.
Bricio-Moreno, L., Chaguza, C., Yahya, R., Shears, R. K., Cornick, J. E., Hokamp, K., . . . Kadioglu, A. (2012). Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.. mBio, 11(6). doi:10.1093/infdis/jis223
2011
Invasive <i>Streptococcus pneumoniae</i> in Children, Malawi, 2004-2006
Cornick, J. E., Everett, D. B., Broughton, C., Denis, B. B., Banda, D. L., Carrol, E. D., & Parry, C. M. (2011). Invasive <i>Streptococcus pneumoniae</i> in Children, Malawi, 2004-2006. EMERGING INFECTIOUS DISEASES, 17(6), 1107-1109. doi:10.3201/eid1706.101404
Undated
Roadmap to resistance: antimicrobial resistance in Malawian pneumococci
Cornick, J. (n.d.). Roadmap to resistance: antimicrobial resistance in Malawian pneumococci. (PhD Thesis, Institute of Infection and Global Health).