Publications
Selected publications
- Role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella (Journal article - 2018)
- RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium. (Journal article - 2015)
- An Infection-Relevant Transcriptomic Compendium for <i>Salmonella enterica</i> Serovar Typhimurium (Journal article - 2013)
- An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes (Journal article - 2021)
- Prophages encode phage-defense systems with cognate self-immunity (Journal article - 2021)
- Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica. (Journal article - 2021)
- Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa (Journal article - 2020)
- The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid (Journal article - 2019)
- Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa (Journal article - 2017)
- Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580 (Journal article - 2019)
2024
Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.
Went, S. C., Picton, D. M., Morgan, R. D., Nelson, A., Brady, A., Mariano, G., . . . Blower, T. R. (2024). Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.. Nature communications, 15(1), 7236. doi:10.1038/s41467-024-51629-7
Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection
Singh Chawla, A., Vandereyken, M., Arias, M., Santiago, L., Dikovskaya, D., Nguyen, C., . . . Swamy, M. (2024). Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection. Mucosal Immunology. doi:10.1016/j.mucimm.2024.08.006
Colicin Receptor CirA Enhances<i>Salmonella</i>Typhimurium’s Resistance to Colicin Ib in the Absence of the Cognate Immunity Protein
Modulation of <i>Salmonella</i> virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.
Yu, X. -J., Xie, H., Li, Y., Liu, M., Hou, R., Predeus, A. V., . . . Thurston, T. L. M. (2024). Modulation of <i>Salmonella</i> virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.. mBio, e0112824. doi:10.1128/mbio.01128-24
High-throughput fitness experiments reveal specific vulnerabilities of human-adapted Salmonella during stress and infection.
Wang, B. X., Leshchiner, D., Luo, L., Tuncel, M., Hokamp, K., Hinton, J. C. D., & Monack, D. M. (2024). High-throughput fitness experiments reveal specific vulnerabilities of human-adapted Salmonella during stress and infection.. Nature genetics, 56(6), 1288-1299. doi:10.1038/s41588-024-01779-7
Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization
Succinate utilisation by Salmonella is inhibited by multiple regulatory systems.
Wenner, N., Zhu, X., Rowe, W. P. M., Händler, K., & Hinton, J. C. D. (2024). Succinate utilisation by Salmonella is inhibited by multiple regulatory systems.. PLoS genetics, 20(3), e1011142. doi:10.1371/journal.pgen.1011142
<i>Salmonella enterica</i> serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage.
Kumwenda, B., Canals, R., Predeus, A. V., Zhu, X., Kröger, C., Pulford, C., . . . Hinton, J. C. D. (2024). <i>Salmonella enterica</i> serovar Typhimurium ST313 sublineage 2.2 has emerged in Malawi with a characteristic gene expression signature and a fitness advantage.. microLife, 5, uqae005. doi:10.1093/femsml/uqae005
Protocol for the challenge non-typhoidal <i>Salmonella</i> (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK.
Smith, C., Smith, E., Rydlova, A., Varro, R., Hinton, J. C. D., Gordon, M. A., . . . Gibani, M. M. (2024). Protocol for the challenge non-typhoidal <i>Salmonella</i> (CHANTS) study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the UK.. BMJ open, 14(1), e076477. doi:10.1136/bmjopen-2023-076477
2023
Diverse Durham collection phages demonstrate complex BREX defense responses
Hinton, J. (2023). Diverse Durham collection phages demonstrate complex BREX defense responses. Applied & Environmental Microbiology. doi:10.1128/aem.00623-23
The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK
Smith, C., Smith, E., Chiu, C., Hinton, J., Perez Sepulveda, B., Gordon, M., . . . CHANTS Consortium. (2023). The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK. Wellcome Open Research. doi:10.12688/wellcomeopenres.19012.2
Class 1 integrons in clinical and swine industry isolates of Salmonella Typhimurium from Colombia, dating 1997 to 2017
Florez-Delgado, N. Y., Ubillus, E. N., Perez-Sepulveda, B., Ospina-Rios, E. L., Carrascal-Camacho, A. K., Chamorro-Tobar, I. C., . . . Wiesner, M. (2023). Class 1 integrons in clinical and swine industry isolates of Salmonella Typhimurium from Colombia, dating 1997 to 2017. JOURNAL OF MEDICAL MICROBIOLOGY, 72(6). doi:10.1099/jmm.0.001704
Genome- wide fitness analysis identifies genes required for in vitro growth and macrophage infection by African and global epidemic pathovariants of Salmonella enterica Enteritidis
Fong, W. Y., Canals, R., Predeus, A. V., Perez-Sepulveda, B., Wenner, N., Lora, L. L., . . . Hinton, J. C. D. (2023). Genome- wide fitness analysis identifies genes required for in vitro growth and macrophage infection by African and global epidemic pathovariants of Salmonella enterica Enteritidis. MICROBIAL GENOMICS, 9(5). doi:10.1099/mgen.0.001017
Enhancing Infectious Intestinal Disease diagnosis through metagenomic and metatranscriptomic sequencing of over 1000 human diarrhoeal samples
The Challenge Non-Typhoidal <i>Salmonella</i> (CHANTS) Consortium: Development of a non-typhoidal <i>Salmonella</i> controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK.
Smith, C., Smith, E., Chiu, C., Hinton, J., Perez Sepulveda, B., Gordon, M., . . . CHANTS Consortium. (2023). The Challenge Non-Typhoidal <i>Salmonella</i> (CHANTS) Consortium: Development of a non-typhoidal <i>Salmonella</i> controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK.. Wellcome open research, 8, 111. doi:10.12688/wellcomeopenres.19012.2
The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK
Smith, C., Smith, E., Chiu, C., Hinton, J., Perez Sepulveda, B., Gordon, M., . . . CHANTS Consortium. (2023). The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK. doi:10.12688/wellcomeopenres.19012.1
2022
Multiplex PCR Assay for Clade Typing of <i>Salmonella enterica</i> Serovar Enteritidis
Gallichan, S., Perez-Sepulveda, B. M., Feasey, N. A., Hinton, J. C. D., Thomas, J., & Smith, A. M. (2022). Multiplex PCR Assay for Clade Typing of <i>Salmonella enterica</i> Serovar Enteritidis. MICROBIOLOGY SPECTRUM, 10(6). doi:10.1128/spectrum.03182-22
Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission.
Koolman, L., Prakash, R., Diness, Y., Msefula, C., Nyirenda, T. S., Olgemoeller, F., . . . Gordon, M. A. (2022). Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission.. PLoS neglected tropical diseases, 16(12), e0010982. doi:10.1371/journal.pntd.0010982
Biogenesis of a bacterial metabolosome for propanediol utilization
Yang, M., Wenner, N., Dykes, G., Li, Y., Zhu, X., Sun, Y., . . . Liu, L. -N. (2022). Biogenesis of a bacterial metabolosome for propanediol utilization. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-30608-w
A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands
Picton, D. M., Harling-Lee, J. D., Duffner, S. J., Went, S. C., Morgan, R. D., Hinton, J. C. D., & Blower, T. R. (2022). A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands. NUCLEIC ACIDS RESEARCH, 50(9), 5191-5207. doi:10.1093/nar/gkac334
How to sequence 10,000 bacterial genomes and retain your sanity: an accessible, efficient and global approach
Perez-Sepulveda, B., Heavens, D., Pulford, C., Predeus, A., Low, R., Webster, H., . . . Hall, N. (2022). How to sequence 10,000 bacterial genomes and retain your sanity: an accessible, efficient and global approach. Access Microbiology, 4(5). doi:10.1099/acmi.ac2021.po0349
Genome-wide fitness analysis identifies genes required for <i>in vitro</i> growth and macrophage infection by African and Global Epidemic pathovariants of <i>Salmonella</i> Enteritidis
Fong, W. Y., Canals, R., Predeus, A., Perez-Sepulveda, B., Wenner, N., Lacharme-Lora, L., . . . Hinton, J. (2022). Genome-wide fitness analysis identifies genes required for <i>in vitro</i> growth and macrophage infection by African and Global Epidemic pathovariants of <i>Salmonella</i> Enteritidis. doi:10.1101/2022.04.06.487138
Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission
Koolman, L., Prakash, R., Diness, Y., Msefula, C., Nyirenda, T., Olgemoeller, F., . . . Gordon, M. (2022). Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission. doi:10.1101/2022.01.31.22270114
Impact of the accessory genome upon the biology of African Salmonella enterica serovar Typhimurium ST313
Zhu, X. (2022). Impact of the accessory genome upon the biology of African Salmonella enterica serovar Typhimurium ST313.
2021
An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes
Perez-Sepulveda, B. M., Heavens, D., Pulford, C. V., Predeus, A. V., Low, R., Webster, H., . . . Hall, N. (2021). An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes. GENOME BIOLOGY, 22(1). doi:10.1186/s13059-021-02536-3
Prophages encode phage-defense systems with cognate self-immunity
Owen, S. V., Wenner, N., Dulberger, C. L., Rodwell, E. V., Bowers-Barnard, A., Quinones-Olvera, N., . . . Hinton, J. C. D. (2021). Prophages encode phage-defense systems with cognate self-immunity. CELL HOST & MICROBE, 29(11), 1620-+. doi:10.1016/j.chom.2021.09.002
The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses
Picton, D. M. L., Luyten, Y. A., Morgan, R. D., Nelson, A., Smith, D. L., Dryden, D. T. F., . . . Blower, T. R. (2021). The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses. NUCLEIC ACIDS RESEARCH, 49(19), 11257-11273. doi:10.1093/nar/gkab906
Characteristics of <i>Salmonella</i> Recovered From Stools of Children Enrolled in the Global Enteric Multicenter Study
Kasumba, I. N., Pulford, C. V., Perez-Sepulveda, B. M., Sen, S., Sayed, N., Permala-Booth, J., . . . Tennant, S. M. (2021). Characteristics of <i>Salmonella</i> Recovered From Stools of Children Enrolled in the Global Enteric Multicenter Study. CLINICAL INFECTIOUS DISEASES, 73(4), 631-641. doi:10.1093/cid/ciab051
Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica.
Powers, T. R., Haeberle, A. L., Predeus, A. V., Hammarlof, D. L., Cundiff, J. A., Saldana-Ahuactzi, Z., . . . Knodler, L. A. (2021). Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of <i>Salmonella enterica</i>. PLOS PATHOGENS, 17(8). doi:10.1371/journal.ppat.1009280
Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease
Exploring the fitness landscape of gastroenteritis-associated and bloodstream infection-associated Salmonella Enteritidis
Fong, W. Y. (2021). Exploring the fitness landscape of gastroenteritis-associated and bloodstream infection-associated Salmonella Enteritidis.
2020
Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa
Pulford, C., Perez-Sepulveda, B. M., Canals, R., Bevington, J. A., Bengtsson, R. J., Wenner, N., . . . Hinton, J. (2020). Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa. Nature Microbiology. doi:10.1038/s41564-020-00836-1
<i>Salmonella</i> identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets
Wilson, C. N., Pulford, C. V., Akoko, J., Perez Sepulveda, B., Predeus, A. V., Bevington, J., . . . Fevre, E. M. (2020). <i>Salmonella</i> identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets. PLOS NEGLECTED TROPICAL DISEASES, 14(11). doi:10.1371/journal.pntd.0008796
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease
Hinton, J., Zhu, X., Owen, S., Gordon, M., & Canals Alvarez, R. (2020). Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease. Proceedings of the National Academy of Sciences of USA, 117(34), 20717-20728. doi:10.1073/pnas.2007472117
Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive <i>Salmonella</i> isolates from Africa
Honeycutt, J. D., Wenner, N., Li, Y., Brewer, S. M., Massis, L. M., Brubaker, S. W., . . . Monack, D. M. (2020). Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive <i>Salmonella</i> isolates from Africa. PLOS PATHOGENS, 16(8). doi:10.1371/journal.ppat.1008763
Prophage-encoded phage defence proteins with cognate self-immunity
Owen, S., Wenner, N., Dulberger, C., Rodwell, E., Bowers-Barnard, A., Quinones-Olvera, N., . . . Hinton, J. (2020). Prophage-encoded phage defense proteins with cognate self-immunity. doi:10.1101/2020.07.13.199331
Decoding the stoichiometric composition and organisation of bacterial metabolosomes
Yang, M., Simpson, D., Wenner, N., Brownridge, P., Harman, V., Hinton, J., . . . Liu, L. (2020). Decoding the stoichiometric composition and organisation of bacterial metabolosomes. Nature Communications, 11(1). doi:10.1038/s41467-020-15888-4
Increased intracellular survival of Salmonella Typhimurium ST313 in HIV-1-infected primary human macrophages is not associated with Salmonella hijacking the HIV compartment.
Lê-Bury, G., Deschamps, C., Kizilyaprak, C., Blanchard, W., Daraspe, J., Dumas, A., . . . Niedergang, F. (2020). Increased intracellular survival of Salmonella Typhimurium ST313 in HIV-1-infected primary human macrophages is not associated with Salmonella hijacking the HIV compartment.. Biol Cell. doi:10.1111/boc.201900055
A window into lysogeny: revealing temperate phage biology with transcriptomics
Owen, S. V., Canals, R., Wenner, N., Hammarlöf, D. L., Kröger, C., & Hinton, J. C. D. (2020). A window into lysogeny: revealing temperate phage biology with transcriptomics. Microbial genomics, 6(2). doi:10.1099/mgen.0.000330
Functional genomics of the insect-vector symbiont, Sodalis glossinidius
Gordon, L. (2020). Functional genomics of the insect-vector symbiont, Sodalis glossinidius.
The genomic epidemiology of nontyphoidal Salmonella serovars and their association with invasive disease
Pulford, C. (2020). The genomic epidemiology of nontyphoidal Salmonella serovars and their association with invasive disease.
2019
A window into lysogeny: Revealing temperate phage biology with transcriptomics
Owen, S., Canals, R., Wenner, N., Hammarlöf, D., Kröger, C., & Hinton, J. (2019). A window into lysogeny: Revealing temperate phage biology with transcriptomics. doi:10.1101/787010
The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid
Hinton, J. C. D. (2019). The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid. PLoS Pathogens, 15(9). doi:10.1371/journal.ppat.1007948
Salmonella Panama: An understudied serovar responsible for extra-intestinal salmonellosis worldwide.
Pulford, C. V., Perez-Sepulveda, B. M., Rodwell, E. V., Weill, F. -X., Baker, K. S., & Hinton, J. C. D. (2019). <i>Salmonella enterica</i> Serovar Panama, an Understudied Serovar Responsible for Extraintestinal Salmonellosis Worldwide. INFECTION AND IMMUNITY, 87(9). doi:10.1128/IAI.00273-19
The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313
Lacharme-Lora, L., Owen, S. V., Blundell, R., Canals, R., Wenner, N., Perez-Sepulveda, B., . . . Hinton, J. C. D. (2019). The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313. PLOS NEGLECTED TROPICAL DISEASES, 13(7). doi:10.1371/journal.pntd.0007540
The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid
Canals, R., Chaudhuri, R., Steiner, R., Owen, S., Quinones-Olvera, N., Gordon, M., . . . Hinton, J. (2019). The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid. doi:10.1101/689075
The diversity, evolution and ecology of Salmonella in venomous snakes
Hinton, J. C. D. (2019). The diversity, evolution and ecology of Salmonella in venomous snakes. PLoS Neglected Tropical Diseases.
Genomic and phylogenetic analysis ofSalmonellaTyphimurium and its monophasic variants responsible for invasive endemic infections in Colombia
Li, Y., Pulford, C., Díaz, P., Perez-Sepulveda, B., Duarte, C., Predeus, A., . . . Hinton, J. (2019). Genomic and phylogenetic analysis of<i>Salmonella</i>Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia. doi:10.1101/588608
Identification of niche-specific virulence factors via experimental evolution of Streptococcus pneumoniae
Green, A., Neill, D., & Hinton, J. (2019). Identification of niche-specific virulence factors via experimental evolution of Streptococcus pneumoniae. Access Microbiology, 1(1A). doi:10.1099/acmi.ac2019.po0515
The diversity, evolution and ecology of <i>Salmonella</i> in venomous snakes
Pulford, C., Wenner, N., Redway, M., Rodwell, E., Webster, H., Escudero, R., . . . Hinton, J. (2019). The diversity, evolution and ecology of <i>Salmonella</i> in venomous snakes. doi:10.1101/526442
Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580
Canals, R., Hammarlöf, D. L., Kröger, C., Owen, S. V., Fong, W. Y., Lacharme-Lora, L., . . . Hinton, J. C. D. (2019). Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580. PLoS Biology, 17(1). doi:10.1371/journal.pbio.3000059
2018
Functional Transcriptomics for Bacterial Gene Detectives
Perez-Sepulveda, B. M., & Hinton, J. C. D. (n.d.). Functional Transcriptomics for Bacterial Gene Detectives. In Regulating with RNA in Bacteria and Archaea (pp. 547-561). ASM Press. doi:10.1128/9781683670247.ch32
The primary transcriptome, small RNAs and regulation of antimicrobial resistance in <i>Acinetobacter baumannii</i> ATCC 17978
Kroger, C., MacKenzie, K. D., Alshabib, E. Y., Kirzinger, M. W. B., Suchan, D. M., Chao, T. -C., . . . Cameron, A. D. S. (2018). The primary transcriptome, small RNAs and regulation of antimicrobial resistance in <i>Acinetobacter baumannii</i> ATCC 17978. NUCLEIC ACIDS RESEARCH, 46(18), 9684-9698. doi:10.1093/nar/gky603
Functional Transcriptomics for Bacterial Gene Detectives.
Perez-Sepulveda, B. M., & Hinton, J. C. D. (2018). Functional Transcriptomics for Bacterial Gene Detectives. MICROBIOLOGY SPECTRUM, 6(5). doi:10.1128/microbiolspec.RWR-0033-2018
Methionine biosynthesis and transport are functionally redundant for the growth and virulence of <i>Salmonella</i> Typhimurium
Ul Husna, A., Wang, N., Cobbold, S. A., Newton, H. J., Hocking, D. M., Wilksch, J. J., . . . Strugnell, R. A. (2018). Methionine biosynthesis and transport are functionally redundant for the growth and virulence of <i>Salmonella</i> Typhimurium. JOURNAL OF BIOLOGICAL CHEMISTRY, 293(24), 9506-9519. doi:10.1074/jbc.RA118.002592
Role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella
Hammarlof, D., Kröger, C., Owen, S. V., Canals, R., Lacharme-Lora,, L., Wenner, N., . . . Hinton, J. C. D. (2018). Role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella. Proceedings of the National Academy of Sciences of the United States of America, 115(11), E2614-E2623. doi:10.1073/pnas.1714718115
2017
The primary transcriptome, small RNAs, and regulation of antimicrobial resistance in<i>Acinetobacter baumannii</i>
Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa
Ashton, P. M., Owen, S. V., Kaindama, L., Rowe, W. P. M., Lane, C. R., Larkin, L., . . . Dallman, T. J. (2017). Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa. GENOME MEDICINE, 9. doi:10.1186/s13073-017-0480-7
The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella
Hammarlöf, D., Kröger, C., Owen, S., Canals, R., Lora, L. L., Wenner, N., . . . Hinton, J. (2017). The role of a single non-coding nucleotide in the evolution of an epidemic African clade of<i>Salmonella</i>. doi:10.1101/175265
InvS Coordinates Expression of PrgH and FimZ and Is Required for Invasion of Epithelial Cells by <i>Salmonella enterica</i> serovar Typhimurium
Wang, L., Cai, X., Wu, S., Bomjan, R., Nakayasu, E. S., Haendler, K., . . . Zhou, D. (2017). InvS Coordinates Expression of PrgH and FimZ and Is Required for Invasion of Epithelial Cells by <i>Salmonella enterica</i> serovar Typhimurium. JOURNAL OF BACTERIOLOGY, 199(13). doi:10.1128/JB.00824-16
Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1
Owen, S. V., Wenner, N., Canals, R., Makumi, A., Hammarlof, D. L., Gordon, M. A., . . . Hinton, J. C. D. (2017). Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1. FRONTIERS IN MICROBIOLOGY, 8. doi:10.3389/fmicb.2017.00235
2016
The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium
Colgan, A. M., Kroger, C., Diard, M., Hardt, W. -D., Puente, J. L., Sivasankaran, S. K., . . . Hinton, J. C. D. (2016). The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium. PLOS GENETICS, 12(8). doi:10.1371/journal.pgen.1006258
2015
RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium.
Srikumar, S., Kroger, C., Hébrard, M., Colgan, A., Owen, S., Sivasankaran, S. K., . . . Hinton, J. (2015). RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium.. PLoS Pathogens, 11(11). doi:10.1371/journal.ppat.1005262
A BTP1 prophage gene present in invasive non-typhoidal <i>Salmonella</i> determines composition and length of the O-antigen of the lipopolysaccharide
Kintz, E., Davies, M. R., Hammarloef, D. L., Canals, R., Hinton, J. C. D., & van der Woude, M. W. (2015). A BTP1 prophage gene present in invasive non-typhoidal <i>Salmonella</i> determines composition and length of the O-antigen of the lipopolysaccharide. MOLECULAR MICROBIOLOGY, 96(2), 263-275. doi:10.1111/mmi.12933
Editorial overview: Genomics: The era of genomically-enabled microbiology
Hall, N., & Hinton, J. (2015). Editorial overview: Genomics: The era of genomically-enabled microbiology. CURRENT OPINION IN MICROBIOLOGY, 23, IX-X. doi:10.1016/j.mib.2014.12.001
Exposure of <i>Salmonella enterica</i> Serovar Typhimurium to Three Humectants Used in the Food Industry Induces Different Osmoadaptation Systems
Finn, S., Rogers, L., Haendler, K., McClure, P., Amezquita, A., Hinton, J. C. D., & Fanning, S. (2015). Exposure of <i>Salmonella enterica</i> Serovar Typhimurium to Three Humectants Used in the Food Industry Induces Different Osmoadaptation Systems. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81(19), 6800-6811. doi:10.1128/AEM.01379-15
2014
A Model System for Studying the Transcriptomic and Physiological Changes Associated with Mammalian Host-Adaptation by <i>Leptospira interrogans</i> Serovar Copenhageni
Caimano, M. J., Sivasankaran, S. K., Allard, A., Hurley, D., Hokamp, K., Grassmann, A. A., . . . Nally, J. E. (2014). A Model System for Studying the Transcriptomic and Physiological Changes Associated with Mammalian Host-Adaptation by <i>Leptospira interrogans</i> Serovar Copenhageni. PLOS PATHOGENS, 10(3). doi:10.1371/journal.ppat.1004004
Comparative analysis of <i>Salmonella</i> susceptibility and tolerance to the biocide chlorhexidine identifies a complex cellular defense network
Condell, O., Power, K. A., Haendler, K., Finn, S., Sheridan, A., Sergeant, K., . . . Fanning, S. (2014). Comparative analysis of <i>Salmonella</i> susceptibility and tolerance to the biocide chlorhexidine identifies a complex cellular defense network. FRONTIERS IN MICROBIOLOGY, 5. doi:10.3389/fmicb.2014.00373
2013
An Infection-Relevant Transcriptomic Compendium for <i>Salmonella enterica</i> Serovar Typhimurium
Kroeger, C., Colgan, A., Srikumar, S., Haendler, K., Sivasankaran, S. K., Hammarloef, D. L., . . . Hinton, J. C. D. (2013). An Infection-Relevant Transcriptomic Compendium for <i>Salmonella enterica</i> Serovar Typhimurium. CELL HOST & MICROBE, 14(6), 683-695. doi:10.1016/j.chom.2013.11.010
The FUN of identifying gene function in bacterial pathogens; insights from <i>Salmonella</i> functional genomics
Hammarloef, D. L., Canals, R., & Hinton, J. C. D. (2013). The FUN of identifying gene function in bacterial pathogens; insights from <i>Salmonella</i> functional genomics. CURRENT OPINION IN MICROBIOLOGY, 16(5), 643-651. doi:10.1016/j.mib.2013.07.009
Phenotypic Characterization of <i>Salmonella</i> Isolated from Food Production Environments Associated with Low-Water Activity Foods
Finn, S., Hinton, J. C. D., McClure, P., Amezquita, A., Martins, M., & Fanning, S. (2013). Phenotypic Characterization of <i>Salmonella</i> Isolated from Food Production Environments Associated with Low-Water Activity Foods. JOURNAL OF FOOD PROTECTION, 76(9), 1488-1499. doi:10.4315/0362-028X.JFP-13-088
ProP Is Required for the Survival of Desiccated <i>Salmonella enterica</i> Serovar Typhimurium Cells on a Stainless Steel Surface
Finn, S., Haendler, K., Condell, O., Colgan, A., Cooney, S., McClure, P., . . . Fanninga, S. (2013). ProP Is Required for the Survival of Desiccated <i>Salmonella enterica</i> Serovar Typhimurium Cells on a Stainless Steel Surface. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(14), 4376-4384. doi:10.1128/AEM.00515-13
ChIP-seq and transcriptome analysis of the OmpR regulon of Salmonella enterica serovars Typhi and Typhimurium reveals accessory genes implicated in host colonization
Perkins, T. T., Davies, M. R., Klemm, E. J., Rowley, G., Wileman, T., James, K., . . . Kingsley, R. A. (2013). ChIP-seq and transcriptome analysis of the OmpR regulon of Salmonella enterica serovars Typhi and Typhimurium reveals accessory genes implicated in host colonization. MOLECULAR MICROBIOLOGY, 87(3), 526-538. doi:10.1111/mmi.12111
Invasive Non-Typhoidal <i>Salmonella</i> Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens
Parsons, B. N., Humphrey, S., Salisbury, A. M., Mikoleit, J., Hinton, J. C. D., Gordon, M. A., & Wigley, P. (2013). Invasive Non-Typhoidal <i>Salmonella</i> Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens. PLOS NEGLECTED TROPICAL DISEASES, 7(10). doi:10.1371/journal.pntd.0002487
Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens
Parsons, B. N., Humphrey, S., Salisbury, A. M., Mikoleit, J., Hinton, J. C. D., Gordon, M. A., & Wigley, P. (n.d.). Invasive Non-Typhoidal Salmonella Typhimurium ST313 Are Not Host-Restricted and Have an Invasive Phenotype in Experimentally Infected Chickens. PLoS Neglected Tropical Diseases, 7(10), e2487. doi:10.1371/journal.pntd.0002487
2012
A third mode of surface-associated growth: immobilization of Salmonella enterica serovar Typhimurium modulates the RpoS-directed transcriptional programme
Knudsen, G. M., Nielsen, M. -B., Grassby, T., Danino-Appleton, V., Thomsen, L. E., Colquhoun, I. J., . . . Hinton, J. C. D. (2012). A third mode of surface-associated growth: immobilization of Salmonella enterica serovar Typhimurium modulates the RpoS-directed transcriptional programme. ENVIRONMENTAL MICROBIOLOGY, 14(8), 1855-1875. doi:10.1111/j.1462-2920.2012.02703.x
The transcriptional landscape and small RNAs of <i>Salmonella enterica</i> serovar Typhimurium
Kroeger, C., Dillon, S. C., Cameron, A. D. S., Papenfort, K., Sivasankaran, S. K., Hokamp, K., . . . Hinton, J. C. D. (2012). The transcriptional landscape and small RNAs of <i>Salmonella enterica</i> serovar Typhimurium. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(20), E1277-E1286. doi:10.1073/pnas.1201061109
Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.
Bricio-Moreno, L., Chaguza, C., Yahya, R., Shears, R. K., Cornick, J. E., Hokamp, K., . . . Kadioglu, A. (2012). Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.. mBio, 11(6). doi:10.1093/infdis/jis223
P4-Mediated Antibody Therapy in an Acute Model of Invasive Pneumococcal Disease
Bangert, M., Bricio-Moreno, L., Gore, S., Rajam, G., Ades, E. W., Gordon, S. B., & Kadioglu, A. (2012). P4-Mediated Antibody Therapy in an Acute Model of Invasive Pneumococcal Disease. JOURNAL OF INFECTIOUS DISEASES, 205(9), 1399-1407. doi:10.1093/infdis/jis223
Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA
Corcoran, C. P., Podkaminski, D., Papenfort, K., Urban, J. H., Hinton, J. C. D., & Vogel, J. (2012). Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA. MOLECULAR MICROBIOLOGY, 84(3), 428-445. doi:10.1111/j.1365-2958.2012.08031.x
The ancestral SgrS RNA discriminates horizontally acquired <i>Salmonella</i> mRNAs through a single G-U wobble pair
Papenfort, K., Podkaminski, D., Hinton, J. C. D., & Vogel, J. (2012). The ancestral SgrS RNA discriminates horizontally acquired <i>Salmonella</i> mRNAs through a single G-U wobble pair. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(13), E757-E764. doi:10.1073/pnas.1119414109
Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation
Rolfe, M. D., Rice, C. J., Lucchini, S., Pin, C., Thompson, A., Cameron, A. D. S., . . . Hinton, J. C. D. (2012). Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation. JOURNAL OF BACTERIOLOGY, 194(3), 686-701. doi:10.1128/JB.06112-11
sRNAs and the virulence of <i>Salmonella enterica</i> serovar Typhimurium
Hebrard, M., Kroeger, C., Srikumar, S., Colgan, A., Haendler, K., & Hinton, J. C. D. (2012). sRNAs and the virulence of <i>Salmonella enterica</i> serovar Typhimurium. RNA BIOLOGY, 9(4), 437-445. doi:10.4161/rna.20480
2011
Cellulose mediates attachment of <i>Salmonella enterica</i> Serovar Typhimurium to tomatoes
Shaw, R. K., Lasa, I., Garcia, B. M., Pallen, M. J., Hinton, J. C. D., Berger, C. N., & Frankel, G. (2011). Cellulose mediates attachment of <i>Salmonella enterica</i> Serovar Typhimurium to tomatoes. ENVIRONMENTAL MICROBIOLOGY REPORTS, 3(5), 569-573. doi:10.1111/j.1758-2229.2011.00263.x
Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA
Sharma, C. M., Papenfort, K., Pernitzsch, S. R., Mollenkopf, H. -J., Hinton, J. C. D., & Vogel, J. (2011). Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA. MOLECULAR MICROBIOLOGY, 81(5), 1144-1165. doi:10.1111/j.1365-2958.2011.07751.x
Nucleoid-associated protein HU controls three regulons that coordinate virulence, response to stress and general physiology in <i>Salmonella enterica</i> serovar Typhimurium
Mangan, M. W., Lucchini, S., Croinin, T. O., Fitzgerald, S., Hinton, J. C. D., & Dorman, C. J. (2011). Nucleoid-associated protein HU controls three regulons that coordinate virulence, response to stress and general physiology in <i>Salmonella enterica</i> serovar Typhimurium. MICROBIOLOGY-SGM, 157, 1075-1087. doi:10.1099/mic.0.046359-0
The challenge of relating gene expression to the virulence of <i>Salmonella</i> <i>enterica</i> serovar Typhimurium
Hebrard, M., Kroeger, C., Sivasankaran, S. K., Haendler, K., & Hinton, J. C. D. (2011). The challenge of relating gene expression to the virulence of <i>Salmonella</i> <i>enterica</i> serovar Typhimurium. CURRENT OPINION IN BIOTECHNOLOGY, 22(2), 200-210. doi:10.1016/j.copbio.2011.02.007
2010
An Incomplete TCA Cycle Increases Survival of <i>Salmonella</i> Typhimurium during Infection of Resting and Activated Murine Macrophages
Bowden, S. D., Ramachandran, V. K., Knudsen, G. M., Hinton, J. C. D., & Thompson, A. (2010). An Incomplete TCA Cycle Increases Survival of <i>Salmonella</i> Typhimurium during Infection of Resting and Activated Murine Macrophages. PLOS ONE, 5(11). doi:10.1371/journal.pone.0013871
Transcriptomic Analysis of <i>Escherichia coli</i> O157:H7 and K-12 Cultures Exposed to Inorganic and Organic Acids in Stationary Phase Reveals Acidulant- and Strain-Specific Acid Tolerance Responses
King, T., Lucchini, S., Hinton, J. C. D., & Gobius, K. (2010). Transcriptomic Analysis of <i>Escherichia coli</i> O157:H7 and K-12 Cultures Exposed to Inorganic and Organic Acids in Stationary Phase Reveals Acidulant- and Strain-Specific Acid Tolerance Responses. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(19), 6514-6528. doi:10.1128/AEM.02392-09
Microarray Analysis of Response of <i>Salmonella</i> during Infection of HLA-B27-Transfected Human Macrophage-Like U937 Cells
Ge, S., Danino, V., He, Q., Hinton, J. C. D., & Granfors, K. (2010). Microarray Analysis of Response of <i>Salmonella</i> during Infection of HLA-B27-Transfected Human Macrophage-Like U937 Cells. BMC GENOMICS, 11. doi:10.1186/1471-2164-11-456
Genome-wide analysis of the H-NS and Sfh regulatory networks in <i>Salmonella</i> Typhimurium identifies a plasmid-encoded transcription silencing mechanism
Dillon, S. C., Cameron, A. D. S., Hokamp, K., Lucchini, S., Hinton, J. C. D., & Dorman, C. J. (2010). Genome-wide analysis of the H-NS and Sfh regulatory networks in <i>Salmonella</i> Typhimurium identifies a plasmid-encoded transcription silencing mechanism. MOLECULAR MICROBIOLOGY, 76(5), 1250-1265. doi:10.1111/j.1365-2958.2010.07173.x
BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets
Alston, M. J., Seers, J., Hinton, J. C. D., & Lucchini, S. (2010). BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets. BMC BIOINFORMATICS, 11. doi:10.1186/1471-2105-11-73
Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in <i>Salmonella enterica</i> serovar Typhimurium is associated with iron restriction and can be reversed by free iron
Layton, A. N., Hudson, D. L., Thompson, A., Hinton, J. C. D., Stevens, J. M., Galyov, E. E., & Stevens, M. P. (2010). Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in <i>Salmonella enterica</i> serovar Typhimurium is associated with iron restriction and can be reversed by free iron. FEMS MICROBIOLOGY LETTERS, 302(2), 114-122. doi:10.1111/j.1574-6968.2009.01847.x
Unphosphorylated CsgD controls biofilm formation in <i>Salmonella enterica</i> serovar Typhimurium
Zakikhany, K., Harrington, C. R., Nimtz, M., Hinton, J. C. D., & Roemling, U. (2010). Unphosphorylated CsgD controls biofilm formation in <i>Salmonella enterica</i> serovar Typhimurium. MOLECULAR MICROBIOLOGY, 77(3), 771-786. doi:10.1111/j.1365-2958.2010.07247.x
2009
The transcriptional programme of <i>Salmonella enterica</i> serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms
Hamilton, S., Bongaerts, R. J. M., Mulholland, F., Cochrane, B., Porter, J., Lucchini, S., . . . Hinton, J. C. D. (2009). The transcriptional programme of <i>Salmonella enterica</i> serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms. BMC GENOMICS, 10. doi:10.1186/1471-2164-10-599
The H-NS-like protein StpA represses the RpoS (σ38) regulon during exponential growth of <i>Salmonella</i> Typhimurium
Lucchini, S., McDermott, P., Thompson, A., & Hinton, J. C. D. (2009). The H-NS-like protein StpA represses the RpoS (σ38) regulon during exponential growth of <i>Salmonella</i> Typhimurium. MOLECULAR MICROBIOLOGY, 74(5), 1169-1186. doi:10.1111/j.1365-2958.2009.06929.x
Network analysis of the transcriptional pattern of young and old cells of <i>Escherichia coli</i> during lag phase
Pin, C., Rolfe, M. D., Munoz-Cuevas, M., Hinton, J. C. D., Peck, M. W., Walton, N. J., & Baranyi, J. (2009). Network analysis of the transcriptional pattern of young and old cells of <i>Escherichia coli</i> during lag phase. BMC SYSTEMS BIOLOGY, 3. doi:10.1186/1752-0509-3-108
Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA
Papenfort, K., Said, N., Welsink, T., Lucchini, S., Hinton, J. C. D., & Vogel, J. (2009). Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA. MOLECULAR MICROBIOLOGY, 74(1), 139-158. doi:10.1111/j.1365-2958.2009.06857.x
Multiple redundant stress resistance mechanisms are induced in <i>Salmonella enterica</i> serovar Typhimurium in response to alteration of the intracellular environment via TLR4 signalling
Wright, J. A., Totemeyer, S. S., Hautefort, I., Appia-Ayme, C., Alston, M., Danino, V., . . . Bryant, C. E. (2009). Multiple redundant stress resistance mechanisms are induced in <i>Salmonella enterica</i> serovar Typhimurium in response to alteration of the intracellular environment via TLR4 signalling. MICROBIOLOGY-SGM, 155, 2919-2929. doi:10.1099/mic.0.030429-0
Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation
Pfeiffer, V., Papenfort, K., Lucchini, S., Hinton, J. C. D., & Vogel, J. (2009). Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 16(8), 840-U63. doi:10.1038/nsmb.1631
Glucose and Glycolysis Are Required for the Successful Infection of Macrophages and Mice by <i>Salmonella enterica</i> Serovar Typhimurium
Bowden, S. D., Rowley, G., Hinton, J. C. D., & Thompson, A. (2009). Glucose and Glycolysis Are Required for the Successful Infection of Macrophages and Mice by <i>Salmonella enterica</i> Serovar Typhimurium. INFECTION AND IMMUNITY, 77(7), 3117-3126. doi:10.1128/IAI.00093-09
The Global Consequence of Disruption of the AcrAB-TolC Efflux Pump in <i>Salmonella enterica</i> Includes Reduced Expression of SPI-1 and Other Attributes Required To Infect the Host
Webber, M. A., Bailey, A. M., Blair, J. M. A., Morgan, E., Stevens, M. P., Hinton, J. C. D., . . . Piddock, L. J. V. (2009). The Global Consequence of Disruption of the AcrAB-TolC Efflux Pump in <i>Salmonella enterica</i> Includes Reduced Expression of SPI-1 and Other Attributes Required To Infect the Host. JOURNAL OF BACTERIOLOGY, 191(13), 4276-4285. doi:10.1128/JB.00363-09
<i>Salmonella</i> Induces Flagellin- and MyD88-Dependent Migration of Bacteria-Capturing Dendritic Cells Into the Gut Lumen
Arques, J. L., Hautefort, I., Ivory, K., Bertelli, E., Regoli, M., Clare, S., . . . Nicoletti, C. (2009). <i>Salmonella</i> Induces Flagellin- and MyD88-Dependent Migration of Bacteria-Capturing Dendritic Cells Into the Gut Lumen. GASTROENTEROLOGY, 137(2), 579-587. doi:10.1053/j.gastro.2009.04.010
All Stressed Out. <i>Salmonella</i> Pathogenesis and Reactive Nitrogen Species
Prior, K., Hautefort, I., Hinton, J. C. D., Richardson, D. J., & Rowley, G. (2009). All Stressed Out. <i>Salmonella</i> Pathogenesis and Reactive Nitrogen Species. In ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 56 (Vol. 56, pp. 1-28). doi:10.1016/S0065-2911(09)05601-X
2008
A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities
Harrington, C. R., Lucchini, S., Ridgway, K. P., Wegmann, U., Eaton, T. J., Hinton, J. C. D., . . . Narbad, A. (2008). A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities. BMC MICROBIOLOGY, 8. doi:10.1186/1471-2180-8-195
Adrenaline modulates the global transcriptional profile of <i>Salmonella</i> revealing a role in the antimicrobial peptide and oxidative stress resistance responses
Karavolos, M. H., Spencer, H., Bulmer, D. M., Thompson, A., Winzer, K., Williams, P., . . . Khan, C. M. A. (2008). Adrenaline modulates the global transcriptional profile of <i>Salmonella</i> revealing a role in the antimicrobial peptide and oxidative stress resistance responses. BMC GENOMICS, 9. doi:10.1186/1471-2164-9-458
Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq
Sittka, A., Lucchini, S., Papenfort, K., Sharma, C. M., Rolle, K., Binnewies, T. T., . . . Vogel, J. (2008). Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq. PLOS GENETICS, 4(8). doi:10.1371/journal.pgen.1000163
Systematic deletion of <i>Salmonella</i> small RNA genes identifies CyaR, a conserved CRP-dependent riboregulator of OmpX synthesis
Papenfort, K., Pfeiffer, V., Lucchini, S., Sonawane, A., Hinton, J. C. D., & Vogel, J. (2008). Systematic deletion of <i>Salmonella</i> small RNA genes identifies CyaR, a conserved CRP-dependent riboregulator of OmpX synthesis. MOLECULAR MICROBIOLOGY, 68(4), 890-906. doi:10.1111/j.1365-2958.2008.06189.x
A combination of cytochrome <i>c</i> nitrite reductase (NrfA) and flavorubredoxin (NorV) protects <i>Salmonella enterica</i> serovar Typhimurium against killing by NO in anoxic environments
Mills, P. C., Rowley, G., Spiro, S., Hinton, J. C. D., & Richardson, D. J. (2008). A combination of cytochrome <i>c</i> nitrite reductase (NrfA) and flavorubredoxin (NorV) protects <i>Salmonella enterica</i> serovar Typhimurium against killing by NO in anoxic environments. MICROBIOLOGY-SGM, 154, 1218-1228. doi:10.1099/mic.0.2007/014290-0
During infection of epithelial cells <i>Salmonella enterica</i> serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems
Hautefort, I., Thompson, A., Eriksson-Ygberg, S., Parker, M. L., Lucchini, S., Danino, V., . . . Hinton, J. C. D. (2008). During infection of epithelial cells <i>Salmonella enterica</i> serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems. CELLULAR MICROBIOLOGY, 10(4), 958-984. doi:10.1111/j.1462-5822.2007.01099.x
Salmonella enterica serovar Typhimurium Induces Rapid Migration of Dendritic Cells into the Gut Lumen
Bertelli, E., Regoli, M., Clare, S., Hautefort, I., Hinton, J., Ivory, K., . . . Arques, J. (2008). Salmonella enterica serovar Typhimurium Induces Rapid Migration of Dendritic Cells into the Gut Lumen. In FASEB JOURNAL Vol. 22. Retrieved from https://www.webofscience.com/
The leucine-responsive regulatory protein, Lrp, activates transcription of the <i>fim</i> operon in <i>Salmonella enterica</i> serovar typhimurium via the <i>fimZ</i> regulatory gene
McFarland, K. A., Lucchini, S., Hinton, J. C. D., & Dorman, C. J. (2008). The leucine-responsive regulatory protein, Lrp, activates transcription of the <i>fim</i> operon in <i>Salmonella enterica</i> serovar typhimurium via the <i>fimZ</i> regulatory gene. JOURNAL OF BACTERIOLOGY, 190(2), 602-612. doi:10.1128/JB.01388-07
<i>Escherichia coli</i> cytochrome <i>c</i> nitrite reductase NrfA
Clarke, T. A., Mills, P. C., Poock, S. R., Butt, J. N., Cheesman, M. R., Cole, J. A., . . . Richardson, D. J. (2008). <i>Escherichia coli</i> cytochrome <i>c</i> nitrite reductase NrfA. GLOBINS AND OTHER NITRIC OXIDE-REACTIVE PROTEINS, PART B, 437, 63-77. doi:10.1016/S0076-6879(07)37004-3
2007
MobilomeFINDER:: web-based tools for <i>in silico</i> and experimental discovery of bacterial genomic islands
Ou, H. -Y., He, X., Harrison, E. M., Kulasekara, B. R., Bin Thani, A., Kadioglu, A., . . . Rajakumar, K. (2007). MobilomeFINDER:: web-based tools for <i>in silico</i> and experimental discovery of bacterial genomic islands. NUCLEIC ACIDS RESEARCH, 35, W97-W104. doi:10.1093/nar/gkm380
H-NS mediates the silencing of laterally acquired genes in bacteria (vol 2, pg 746, 2006)
Lucchini, S., Rowley, G., Goldberg, M. D., Hurd, D., Harrison, M., & Hinton, J. C. D. (2007). H-NS mediates the silencing of laterally acquired genes in bacteria (vol 2, pg 746, 2006). PLOS PATHOGENS, 3(3). doi:10.1371/journal.ppat.0030038
SseL, a <i>Salmonella</i> deubiquitinase required for macrophage killing and virulence
Rytkonen, A., Poh, J., Garmendia, J., Boyle, C., Thompson, A., Liu, M., . . . Holden, D. W. (2007). SseL, a <i>Salmonella</i> deubiquitinase required for macrophage killing and virulence. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(9), 3502-3507. doi:10.1073/pnas.0610095104
Regulation of <i>Salmonella enterica</i> <i>Serovar Enteritidis</i> genes by HLA-B27 during intracellular growth in human monocytic U937 cells
Ge, S., Danino, V., He, Q., Hinton, J. C. D., & Granfors, K. (2007). Regulation of <i>Salmonella enterica</i> <i>Serovar Enteritidis</i> genes by HLA-B27 during intracellular growth in human monocytic U937 cells. In SCANDINAVIAN JOURNAL OF IMMUNOLOGY Vol. 65 (pp. 596-597). Retrieved from https://www.webofscience.com/
2006
Developments and pitfalls of feed acidification in controlling gut pathogens in poultry, with emphasis on Salmonella.
Immerseel, F. V., Gantois, I., Bohez, L., Timbermont, L., Boyen, F., Hautefort, I., . . . Ducatelle, R. (2006). Developments and pitfalls of feed acidification in controlling gut pathogens in poultry, with emphasis on Salmonella.. In Avian gut function in health and disease (pp. 275-293). CABI. doi:10.1079/9781845931803.0275
DNA adenine methylation regulates virulence gene expression in <i>Salmonella enterica</i> serovar typhimurium
Balbontin, R., Rowley, G., Pucciarelli, M. G., Lopez-Garrido, J., Wormstone, Y., Lucchini, S., . . . Casadesus, J. (2006). DNA adenine methylation regulates virulence gene expression in <i>Salmonella enterica</i> serovar typhimurium. JOURNAL OF BACTERIOLOGY, 188(23), 8160-8168. doi:10.1128/JB.00847-06
σ<SUP>E</SUP>-dependent small RNAs of <i>Salmonella</i> respond to membrane stress by accelerating global <i>omp</i> mRNA decay
Papenfort, K., Pfeiffer, V., Mika, F., Lucchini, S., Hinton, J. C. D., & Vogel, J. (2006). σ<SUP>E</SUP>-dependent small RNAs of <i>Salmonella</i> respond to membrane stress by accelerating global <i>omp</i> mRNA decay. MOLECULAR MICROBIOLOGY, 62(6), 1674-1688. doi:10.1111/j.1365-2958.2006.05524.x
The bacterial signal molecule, ppGpp, mediates the environmental regulation of both the invasion and intracellular virulence gene programs of <i>Salmonella</i>
Thompson, A., Rolfe, M. D., Lucchini, S., Schwerk, P., Hinton, J. C. D., & Tedin, K. (2006). The bacterial signal molecule, ppGpp, mediates the environmental regulation of both the invasion and intracellular virulence gene programs of <i>Salmonella</i>. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(40), 30112-30121. doi:10.1074/jbc.M605616200
Down-regulation of key virulence factors makes the <i>Salmonella enterica</i> serovar Typhimurium <i>rfaH</i> mutant a promising live-attenuated vaccine candidate
Nagy, G., Danino, V., Dobrindt, U., Pallen, M., Chaudhuri, R., Emody, L., . . . Hacker, J. (2006). Down-regulation of key virulence factors makes the <i>Salmonella enterica</i> serovar Typhimurium <i>rfaH</i> mutant a promising live-attenuated vaccine candidate. INFECTION AND IMMUNITY, 74(10), 5914-5925. doi:10.1128/IAI.00619-06
The lactic acid-induced acid tolerance response in <i>Salmonella enterica</i> serovar typhimurium induces sensitivity to hydrogen peroxide
Greenacre, E. J., Lucchini, S., Hinton, J. C. D., & Brocklehurst, T. F. (2006). The lactic acid-induced acid tolerance response in <i>Salmonella enterica</i> serovar typhimurium induces sensitivity to hydrogen peroxide. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(8), 5623-5625. doi:10.1128/AEM.00538-06
The integration host factor (IHF) integrates stationary-phase and virulence gene expression in <i>Salmonella enterica</i> serovar Typhimurium
Mangan, M. W., Lucchini, S., Danino, V., Cróinín, T. O., Hinton, J. C. D., & Dorman, C. J. (2006). The integration host factor (IHF) integrates stationary-phase and virulence gene expression in <i>Salmonella enterica</i> serovar Typhimurium. MOLECULAR MICROBIOLOGY, 59(6), 1831-1847. doi:10.1111/j.1365-2958.2006.05062.x
<i>Salmonella</i> transcriptomics:: relating regulons, stimulons and regulatory networks to the process of infection
Thompson, A., Rowley, G., Alston, M., Danino, V., & Hinton, J. C. D. (2006). <i>Salmonella</i> transcriptomics:: relating regulons, stimulons and regulatory networks to the process of infection. CURRENT OPINION IN MICROBIOLOGY, 9(1), 109-116. doi:10.1016/j.mib.2005.12.010
Polynucleotide phosphorylase negatively controls <i>spv</i> virulence gene expression in <i>Salmonella enterica</i>
Ygberg, S. E., Clements, M. O., Rytkönen, A., Thompson, A., Holden, D. W., Hinton, J. C. D., & Rhen, M. (2006). Polynucleotide phosphorylase negatively controls <i>spv</i> virulence gene expression in <i>Salmonella enterica</i>. INFECTION AND IMMUNITY, 74(2), 1243-1254. doi:10.1128/IAI.74.2.1243-1254.2006
A novel strategy for the identification of genomic islands by comparative analysis of the contents and contexts of tRNA sites in closely related bacteria
Ou, H. Y., Chen, L. L., Lonnen, J., Chaudhuri, R. R., Thani, A. B., Smith, R., . . . Rajakumar, K. (2006). A novel strategy for the identification of genomic islands by comparative analysis of the contents and contexts of tRNA sites in closely related bacteria. NUCLEIC ACIDS RESEARCH, 34(1). doi:10.1093/nar/gnj005
Butyrate specifically down-regulates <i>Salmonella</i> pathogenicity island 1 gene expression
Gantois, I., Ducatelle, R., Pasmans, F., Haesebrouck, F., Hautefort, I., Thompson, A., . . . Van Immerseel, F. (2006). Butyrate specifically down-regulates <i>Salmonella</i> pathogenicity island 1 gene expression. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(1), 946-949. doi:10.1128/AEM.72.1.946-949.2006
H-NS mediates the silencing of laterally acquired genes in bacteria
Lucchini, S., Rowley, G., Goldberg, M. D., Hurd, D., Harrison, M., & Hinton, J. C. D. (2006). H-NS mediates the silencing of laterally acquired genes in bacteria. PLOS PATHOGENS, 2(8), 746-752. doi:10.1371/journal.ppat.0020081
2005
H-NS is a part of a thermally controlled mechanism for bacterial gene regulation
Ono, S., Goldberg, M. D., Olsson, T., Esposito, D., Hinton, J. C. D., & Ladbury, J. E. (2005). H-NS is a part of a thermally controlled mechanism for bacterial gene regulation. BIOCHEMICAL JOURNAL, 391, 203-213. doi:10.1042/BJ20050453
Bacterial genome size reduction by experimental evolution
Nilsson, A. I., Koskiniemi, S., Eriksson, S., Kugelberg, E., Hinton, J. C. D., & Andersson, D. I. (2005). Bacterial genome size reduction by experimental evolution. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(34), 12112-12116. doi:10.1073/pnas.0503654102
Detoxification of nitric oxide by the flavorubredoxin of <i>Salmonella enterica</i> serovar Typhimurium
Mills, P. C., Richardson, D. J., Hinton, J. C. D., & Spiro, S. (2005). Detoxification of nitric oxide by the flavorubredoxin of <i>Salmonella enterica</i> serovar Typhimurium. BIOCHEMICAL SOCIETY TRANSACTIONS, 33, 198-199. doi:10.1042/BST0330198
ArrayOme: a program for estimating the sizes of microarray-visualized bacterial genomes
Ou, H. Y., Smith, R., Lucchini, S., Hinton, J., Chaudhuri, R. R., Pallen, M., . . . Rajakumar, K. (2005). ArrayOme: a program for estimating the sizes of microarray-visualized bacterial genomes. NUCLEIC ACIDS RESEARCH, 33(1). doi:10.1093/nar/gni005
Comparative imaging of a bacterial surface-located GFP fusion protein by epifluorescence and scanning near-field optical microscopy
Gunning, A. P., Bongaerts, R. J. M., Kirby, A. R., Hinton, J. C. D., & Morris, V. J. (2005). Comparative imaging of a bacterial surface-located GFP fusion protein by epifluorescence and scanning near-field optical microscopy. JOURNAL OF MICROSCOPY, 218, 46-51. doi:10.1111/j.1365-2818.2005.01464.x
Transcriptional adaptation of <i>Shigella flexneri</i> during infection of macrophages and epithelial cells:: Insights into the strategies of a cytosolic bacterial pathogen
Lucchini, S., Liu, H., Jin, Q., Hinton, J. C. D., & Yu, J. (2005). Transcriptional adaptation of <i>Shigella flexneri</i> during infection of macrophages and epithelial cells:: Insights into the strategies of a cytosolic bacterial pathogen. INFECTION AND IMMUNITY, 73(1), 88-102. doi:10.1128/IAI.73.1.88-102.2005
2004
Identification of a new member of the phage shock protein response in <i>Escherichia coli</i>, the phage shock protein g (PspG)
Lloyd, L. J., Jones, S. E., Jovanovic, G., Gyaneshwar, P., Rolfe, M. D., Thompson, A., . . . Buck, M. (2004). Identification of a new member of the phage shock protein response in <i>Escherichia coli</i>, the phage shock protein g (PspG). JOURNAL OF BIOLOGICAL CHEMISTRY, 279(53), 55707-55714. doi:10.1074/jbc.M408994200
Novel phenotypes of <i>Escherichia coli tat</i> mutants revealed by global gene expression and phenotypic analysis
Ize, B., Porcelli, I., Lucchini, S., Hinton, J. C., Berks, B. C., & Palmer, T. (2004). Novel phenotypes of <i>Escherichia coli tat</i> mutants revealed by global gene expression and phenotypic analysis. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(46), 47543-47554. doi:10.1074/jbc.M406910200
A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium
Kelly, A., Goldberg, M. D., Carroll, R. K., Danino, V., Hinton, J. C. D., & Dorman, C. J. (2004). A global role for Fis in the transcriptional control of metabolism and type III secretion in Salmonella enterica serovar Typhimurium. Microbiology, 150(7), 2037-2053. doi:10.1099/mic.0.27209-0
Benefits and pitfalls of using microarrays to monitor bacterial gene expression during infection
Hinton, J. C. D., Hautefort, I., Eriksson, S., Thompson, A., & Rhen, M. (2004). Benefits and pitfalls of using microarrays to monitor bacterial gene expression during infection. CURRENT OPINION IN MICROBIOLOGY, 7(3), 277-282. doi:10.1016/j.mib.2004.04.009
H-NS represses <i>Salmonella enterica</i> serovar Typhimurium <i>dsbA</i> expression during exponential growth
Gallant, C. V., Ponnampalam, T., Spencer, H., Hinton, J. C. D., & Martin, N. L. (2004). H-NS represses <i>Salmonella enterica</i> serovar Typhimurium <i>dsbA</i> expression during exponential growth. JOURNAL OF BACTERIOLOGY, 186(4), 910-918. doi:10.1128/JB.186.4.910-918.2004
Transcriptional profiling of colicin-induced cell death of <i>Escherichia coli</i> MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity
Walker, D., Rolfe, M., Thompson, A., Moore, G. R., James, R., Hinton, J. C. D., & Kleanthous, C. (2004). Transcriptional profiling of colicin-induced cell death of <i>Escherichia coli</i> MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity. JOURNAL OF BACTERIOLOGY, 186(3), 866-869. doi:10.1128/JB.186.3.866-869.2004
A global role for Fis in the transcriptional control of metabolism and type III secretion in <i>Salmonella enterica</i> serovar Typhimurium
Kelly, A., Goldberg, M. D., Carroll, R. K., Danino, V., Hinton, J. C. D., & Dorman, C. J. (2004). A global role for Fis in the transcriptional control of metabolism and type III secretion in <i>Salmonella enterica</i> serovar Typhimurium. MICROBIOLOGY-SGM, 150, 2037-2053. doi:10.1099/mic.0.27209-0
2003
Single-copy green fluorescent protein gene fusions allow accurate measurement of <i>Salmonella</i> gene expression in vitro and during infection of mammalian cells
Hautefort, I., Proença, M. J., & Hinton, J. C. D. (2003). Single-copy green fluorescent protein gene fusions allow accurate measurement of <i>Salmonella</i> gene expression in vitro and during infection of mammalian cells. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69(12), 7480-7491. doi:10.1128/AEM.69.12.7480-7491.2003
Comparative genomic indexing reveals the phylogenomics of <i>Escherichia coli</i> pathogens
Anjum, M. F., Lucchini, S., Thompson, A., Hinton, J. C. D., & Woodward, M. J. (2003). Comparative genomic indexing reveals the phylogenomics of <i>Escherichia coli</i> pathogens. INFECTION AND IMMUNITY, 71(8), 4674-4683. doi:10.1128/IAI.71.8.4674-4683.2003
Unravelling the biology of macrophage infection by gene expression profiling of intracellular <i>Salmonella enterica</i>
Eriksson, S., Lucchini, S., Thompson, A., Rhen, M., & Hinton, J. C. D. (2003). Unravelling the biology of macrophage infection by gene expression profiling of intracellular <i>Salmonella enterica</i>. MOLECULAR MICROBIOLOGY, 47(1), 103-118. doi:10.1046/j.1365-2958.2003.03313.x
2002
H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein
Esposito, D., Petrovic, A., Harris, R., Ono, S., Eccleston, J. F., Mbabaali, A., . . . Ladbury, J. E. (2002). H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein. JOURNAL OF MOLECULAR BIOLOGY, 324(4), 841-850. doi:10.1016/S0022-2836(02)01141-5
Polynucleotide phosphorylase is a global regulator of virulence and persistency in <i>Salmonella enterica</i>
Clements, M. O., Eriksson, S., Thompson, A., Lucchini, S., Hinton, J. C. D., Normark, S., & Rhen, M. (2002). Polynucleotide phosphorylase is a global regulator of virulence and persistency in <i>Salmonella enterica</i>. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(13), 8784-8789. doi:10.1073/pnas.132047099
4 Molecular methods for monitoring bacterial gene expression during infection
Hautefort, I., & Hinton, J. C. D. (2002). 4 Molecular methods for monitoring bacterial gene expression during infection (Vol. 31). doi:10.1016/s0580-9517(02)31005-5
Green fluorescent protein as a marker for conditional gene expression in bacterial cells
Bongaerts, R. J. M., Hautefort, I., Sidebotham, J. M., & Hinton, J. C. D. (2002). Green fluorescent protein as a marker for conditional gene expression in bacterial cells. BACTERIAL PATHOGENESIS, PT C, 358, 43-66. Retrieved from https://www.webofscience.com/
Molecular methods for monitoring bacterial gene expression during infection
Hautefort, I., & Hinton, J. C. D. (2002). Molecular methods for monitoring bacterial gene expression during infection. MOLECULAR CELLULAR MICROBIOLOGY, 31, 55-91. doi:10.1016/S0580-9517(02)31005-5
2001
Role of the nucleoid-associated protein Fis in the regulation of virulence properties of enteropathogenic <i>Escherichia coli</i>
Goldberg, M. D., Johnson, M., Hinton, J. C. D., & Williams, P. H. (2001). Role of the nucleoid-associated protein Fis in the regulation of virulence properties of enteropathogenic <i>Escherichia coli</i>. MOLECULAR MICROBIOLOGY, 41(3), 549-559. doi:10.1046/j.1365-2958.2001.02526.x
Microarrays for microbiologists
Lucchini, S., Thompson, A., & Hinton, J. C. D. (2001). Microarrays for microbiologists. MICROBIOLOGY-SGM, 147, 1403-1414. doi:10.1099/00221287-147-6-1403
It's easy to build your own microarrayer!
Thompson, A., Lucchini, S., & Hinton, J. C. D. (2001). It's easy to build your own microarrayer!. TRENDS IN MICROBIOLOGY, 9(4), 154-156. doi:10.1016/S0966-842X(01)01977-1
Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS
Renzoni, D., Esposito, D., Pfuhl, M., Hinton, J. C. D., Higgins, C. F., Driscoll, P. C., & Ladbury, J. E. (2001). Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS. JOURNAL OF MOLECULAR BIOLOGY, 306(5), 1127-1137. doi:10.1006/jmbi.2001.4471
The nucleoid-associated protein StpA binds curved DNA, has a greater DNA-binding affinity than H-NS and is present in significant levels in <i>hns</i> mutants
Sonnenfield, J. M., Burns, C. M., Higgins, C. F., & Hinton, J. C. D. (2001). The nucleoid-associated protein StpA binds curved DNA, has a greater DNA-binding affinity than H-NS and is present in significant levels in <i>hns</i> mutants. BIOCHIMIE, 83(2), 243-249. doi:10.1016/S0300-9084(01)01232-9
Virulence gene regulation in <i>Salmonella enterica</i>
Clements, M., Eriksson, S., Tezcan-Merdol, D., Hinton, J. C. D., & Rhen, M. (2001). Virulence gene regulation in <i>Salmonella enterica</i>. ANNALS OF MEDICINE, 33(3), 178-185. doi:10.3109/07853890109002075
2000
Oligomerization of the chromatin-structuring protein H-NS
Smyth, C. P., Lundbäck, T., Renzoni, D., Siligardi, G., Beavil, R., Layton, M., . . . Ladbury, J. E. (2000). Oligomerization of the chromatin-structuring protein H-NS. MOLECULAR MICROBIOLOGY, 36(4), 962-972. doi:10.1046/j.1365-2958.2000.01917.x
Measurement of bacterial gene expression <i>in vivo</i>
Hautefort, I., & Hinton, J. C. D. (2000). Measurement of bacterial gene expression <i>in vivo</i>. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 355(1397), 601-611. doi:10.1098/rstb.2000.0601
1999
Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria
Dorman, C. J., Hinton, J. C. D., & Free, A. (1999). Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria. TRENDS IN MICROBIOLOGY, 7(3), 124-128. doi:10.1016/S0966-842X(99)01455-9
1998
7.2 Genetic Approaches to the Study of Pathogenic Salmonellae
Hinton, J. C. D. (1998). 7.2 Genetic Approaches to the Study of Pathogenic Salmonellae. Unknown Journal, 349-357. doi:10.1016/s0580-9517(08)70296-4
Genetic approaches to the study of pathogenic <i>Salmonellae</i>
Hinton, J. C. D. (1998). Genetic approaches to the study of pathogenic <i>Salmonellae</i>. METHODS IN MICROBIOLOGY, VOL 27, 27, 349-357. Retrieved from https://www.webofscience.com/
1997
The Escherichia coli genome sequence: the end of an era or the start of the FUN?
Hinton, J. C. D. (1997). The Escherichia coli genome sequence: the end of an era or the start of the FUN?. MOLECULAR MICROBIOLOGY, 26(3), 417-422. doi:10.1046/j.1365-2958.1997.6371988.x
DNA binding is not sufficient for H-NS-mediated repression of proU expression
Jordi, B. J. A. M., Fielder, A. E., Burns, C. M., Hinton, J. C. D., Dover, N., Ussery, D. W., & Higgins, C. F. (1997). DNA binding is not sufficient for H-NS-mediated repression of proU expression. JOURNAL OF BIOLOGICAL CHEMISTRY, 272(18), 12083-12090. doi:10.1074/jbc.272.18.12083
The Escherichia coli genome sequence: the end of an era or the start of the FUN?
Hinton, J. C. (1997). The Escherichia coli genome sequence: the end of an era or the start of the FUN?. Molecular microbiology, 26(3), 417-422. doi:10.1046/j.1365-2958.1997.6371988.x
1994
THE CHROMATIN-ASSOCIATED PROTEIN H-NS
USSERY, D. W., HINTON, J. C. D., JORDI, B., GRANUM, P. E., SEIRAFI, A., STEPHEN, R. J., . . . HIGGINS, C. F. (1994). THE CHROMATIN-ASSOCIATED PROTEIN H-NS. BIOCHIMIE, 76(10-11), 968-980. doi:10.1016/0300-9084(94)90022-1
THE CHROMATIN-ASSOCIATED PROTEIN H-NS ALTERS DNA TOPOLOGY IN-VITRO
TUPPER, A. E., OWENHUGHES, T. A., USSERY, D. W., SANTOS, D. S., FERGUSON, D. J. P., SIDEBOTHAM, J. M., . . . HIGGINS, C. F. (1994). THE CHROMATIN-ASSOCIATED PROTEIN H-NS ALTERS DNA TOPOLOGY IN-VITRO. EMBO JOURNAL, 13(1), 258-268. doi:10.1002/j.1460-2075.1994.tb06256.x
1993
A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS
MULHOLLAND, V., HINTON, J. C. D., SIDEBOTHAM, J., TOTH, I. K., HYMAN, L. J., PEROMBELON, M. C. M., . . . SALMOND, G. P. C. (1993). A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS. MOLECULAR MICROBIOLOGY, 9(2), 343-356. doi:10.1111/j.1365-2958.1993.tb01695.x
A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS (VOL 9, PG 343, 1993)
MULHOLLAND, V., HINTON, J. C. D., SIDEBOTHAM, J., TOTH, I. K., HYMAN, L. J., PEROMBELON, M. C. M., . . . SALMOND, G. P. C. (1993). A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS (VOL 9, PG 343, 1993). MOLECULAR MICROBIOLOGY, 10(5), 1154. doi:10.1111/j.1365-2958.1993.tb00986.x
H-NS - A NOVEL DNA-BINDING PROTEIN INVOLVED IN MAINTAINING CHROMATIN STRUCTURE AND REGULATING GENE-EXPRESSION
HINTON, J. C. D., PAVITT, G. D., OWENHUGHES, T. A., SANTOS, D. S., SEIRAFI, A., SIDEBOTHAM, J. M., & HIGGINS, C. F. (1993). H-NS - A NOVEL DNA-BINDING PROTEIN INVOLVED IN MAINTAINING CHROMATIN STRUCTURE AND REGULATING GENE-EXPRESSION. JOURNAL OF CELLULAR BIOCHEMISTRY, 295. Retrieved from https://www.webofscience.com/
1992
THE CHROMATIN-ASSOCIATED PROTEIN H-NS INTERACTS WITH CURVED DNA TO INFLUENCE DNA TOPOLOGY AND GENE-EXPRESSION
OWENHUGHES, T. A., PAVITT, G. D., SANTOS, D. S., SIDEBOTHAM, J. M., HULTON, C. S. J., HINTON, J. C. D., & HIGGINS, C. F. (1992). THE CHROMATIN-ASSOCIATED PROTEIN H-NS INTERACTS WITH CURVED DNA TO INFLUENCE DNA TOPOLOGY AND GENE-EXPRESSION. CELL, 71(2), 255-265. doi:10.1016/0092-8674(92)90354-F
EXPRESSION AND MUTATIONAL ANALYSIS OF THE NUCLEOID-ASSOCIATED PROTEIN H-NS OF SALMONELLA-TYPHIMURIUM
HINTON, J. C. D., SANTOS, D. S., SEIRAFI, A., HULTON, C. S. J., PAVITT, G. D., & HIGGINS, C. F. (1992). EXPRESSION AND MUTATIONAL ANALYSIS OF THE NUCLEOID-ASSOCIATED PROTEIN H-NS OF SALMONELLA-TYPHIMURIUM. MOLECULAR MICROBIOLOGY, 6(16), 2327-2337. doi:10.1111/j.1365-2958.1992.tb01408.x
1991
A SIMPLE AND RAPID METHOD OF DIRECT SEQUENCING USING DYNABEADS
THEIN, S. L., & HINTON, J. (1991). A SIMPLE AND RAPID METHOD OF DIRECT SEQUENCING USING DYNABEADS. BRITISH JOURNAL OF HAEMATOLOGY, 79(1), 113-115. doi:10.1111/j.1365-2141.1991.tb08016.x
1990
HISTONE-LIKE PROTEIN H1 (H-NS), DNA SUPERCOILING, AND GENE-EXPRESSION IN BACTERIA
HULTON, C. S. J., SEIRAFI, A., HINTON, J. C. D., SIDEBOTHAM, J. M., WADDELL, L., PAVITT, G. D., . . . HIGGINS, C. F. (1990). HISTONE-LIKE PROTEIN H1 (H-NS), DNA SUPERCOILING, AND GENE-EXPRESSION IN BACTERIA. CELL, 63(3), 631-642. doi:10.1016/0092-8674(90)90458-Q
PROTEIN-H1 - A ROLE FOR CHROMATIN STRUCTURE IN THE REGULATION OF BACTERIAL GENE-EXPRESSION AND VIRULENCE
HIGGINS, C. F., HINTON, J. C. D., HULTON, C. S. J., OWENHUGHES, T., PAVITT, G. D., & SEIRAFI, A. (1990). PROTEIN-H1 - A ROLE FOR CHROMATIN STRUCTURE IN THE REGULATION OF BACTERIAL GENE-EXPRESSION AND VIRULENCE. MOLECULAR MICROBIOLOGY, 4(12), 2007-2012. doi:10.1111/j.1365-2958.1990.tb00559.x
SEQUENCE OF THE PEH GENE OF ERWINIA-CAROTOVORA - HOMOLOGY BETWEEN ERWINIA AND PLANT ENZYMES
HINTON, J. C. D., GILL, D. R., LALO, D., PLASTOW, G. S., & SALMOND, G. P. C. (1990). SEQUENCE OF THE PEH GENE OF ERWINIA-CAROTOVORA - HOMOLOGY BETWEEN ERWINIA AND PLANT ENZYMES. MOLECULAR MICROBIOLOGY, 4(6), 1029-1036. doi:10.1111/j.1365-2958.1990.tb00675.x
1989
ISOLATION AND CHARACTERIZATION OF TRANSPOSON-INDUCED MUTANTS OF ERWINIA-CAROTOVORA SUBSP ATROSEPTICA EXHIBITING REDUCED VIRULENCE
HINTON, J. C. D., SIDEBOTHAM, J. M., HYMAN, L. J., PEROMBELON, M. C. M., & SALMOND, G. P. C. (1989). ISOLATION AND CHARACTERIZATION OF TRANSPOSON-INDUCED MUTANTS OF ERWINIA-CAROTOVORA SUBSP ATROSEPTICA EXHIBITING REDUCED VIRULENCE. MOLECULAR AND GENERAL GENETICS, 217(1), 141-148. doi:10.1007/BF00330953
EXTRACELLULAR AND PERIPLASMIC ISOENZYMES OF PECTATE LYASE FROM ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA BELONG TO DIFFERENT GENE FAMILIES
HINTON, J. C. D., SIDEBOTHAM, J. M., GILL, D. R., & SALMOND, G. P. C. (1989). EXTRACELLULAR AND PERIPLASMIC ISOENZYMES OF PECTATE LYASE FROM ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA BELONG TO DIFFERENT GENE FAMILIES. MOLECULAR MICROBIOLOGY, 3(12), 1785-1795. doi:10.1111/j.1365-2958.1989.tb00164.x
1987
CLONING OF THE CYSB GENE OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA, AND THE IDENTIFICATION OF ITS PRODUCT
HINTON, J., PEROMBELON, M. C. M., & SALMOND, G. P. C. (1987). CLONING OF THE CYSB GENE OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA, AND THE IDENTIFICATION OF ITS PRODUCT. MOLECULAR & GENERAL GENETICS, 207(2-3), 466-470. doi:10.1007/BF00331616
The Application of Transposons to the Cloning of Genes from Erwinia Carotovora
Hinton, J. C. D., Perombelon, M. C. M., & Salmond, G. P. C. (1987). The Application of Transposons to the Cloning of Genes from Erwinia Carotovora. In Current Plant Science and Biotechnology in Agriculture (pp. 244-248). Springer Netherlands. doi:10.1007/978-94-009-3555-6_37
USE OF TNPHOA TO ENRICH FOR EXTRACELLULAR ENZYME MUTANTS OF ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA
HINTON, J. C. D., & SALMOND, G. P. C. (1987). USE OF TNPHOA TO ENRICH FOR EXTRACELLULAR ENZYME MUTANTS OF ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA. MOLECULAR MICROBIOLOGY, 1(3), 381-386. doi:10.1111/j.1365-2958.1987.tb01946.x
1986
TRANSPOSON MUTAGENESIS OF ERWINIA USING PHAGE-LAMBDA VECTORS
SALMOND, G. P. C., HINTON, J. C. D., GILL, D. R., & PEROMBELON, M. C. M. (1986). TRANSPOSON MUTAGENESIS OF ERWINIA USING PHAGE-LAMBDA VECTORS. MOLECULAR & GENERAL GENETICS, 203(3), 524-528. doi:10.1007/BF00422080
MOLECULAR-CLONING OF PECTINASE GENES FROM ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA (STRAIN SCRI193)
PLASTOW, G. S., BORDER, P. M., HINTON, J. C. D., & SALMOND, G. P. C. (1986). MOLECULAR-CLONING OF PECTINASE GENES FROM ERWINIA-CAROTOVORA SUBSPECIES CAROTOVORA (STRAIN SCRI193). SYMBIOSIS, 2(1-3), 115-122. Retrieved from https://www.webofscience.com/
1985
Nonsense-suppressor mutants of Erwinia carotovora subsp. carotovora
Hinton, J. (1985). Nonsense-suppressor mutants of Erwinia carotovora subsp. carotovora. FEMS Microbiology Letters, 28(1), 103-106. doi:10.1016/0378-1097(85)90226-5
EFFICIENT TRANSFORMATION OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA AND ERWINIA-CAROTOVORA SUBSP ATROSEPTICA
HINTON, J. C. D., PEROMBELON, M. C. M., & SALMOND, G. P. C. (1985). EFFICIENT TRANSFORMATION OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA AND ERWINIA-CAROTOVORA SUBSP ATROSEPTICA. JOURNAL OF BACTERIOLOGY, 161(2), 786-788. doi:10.1128/JB.161.2.786-788.1985
NONSENSE-SUPPRESSOR MUTANTS OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA
HINTON, J. C. D., PEROMBELON, M. C. M., & SALMOND, G. P. C. (1985). NONSENSE-SUPPRESSOR MUTANTS OF ERWINIA-CAROTOVORA SUBSP CAROTOVORA. FEMS MICROBIOLOGY LETTERS, 28(1), 103-106. doi:10.1016/0378-1097(85)90226-5
1983
A GENETIC-STUDY OF ERWINIA-CAROTOVORA
FORBES, K. J., & HINTON, J. C. D. (1983). A GENETIC-STUDY OF ERWINIA-CAROTOVORA. In HEREDITY Vol. 51 (pp. 536). Retrieved from https://www.webofscience.com/